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Color-Blind Resilience: How Uniform Climate Standards Reproduce Environmental Inequality In The Rockaways, Aaryan M. Nair Jan 2026

Color-Blind Resilience: How Uniform Climate Standards Reproduce Environmental Inequality In The Rockaways, Aaryan M. Nair

Publications and Research

This paper examines how ostensibly uniform climate resilience standards can reproduce environmental inequality in socially uneven landscapes, using the Rockaway Peninsula in New York City as a critical case study. While flood-resistant building codes, zoning regulations, and insurance frameworks are designed to provide equal protection across flood-prone areas, this analysis argues that their “color-blind” application obscures and intensifies underlying disparities in financial capacity, housing conditions, and tenure. Drawing on environmental justice (EJ) theory, the paper identifies two key mechanisms through which inequality is reproduced. First, “code without capacity” demonstrates how uniform technical standards—such as elevation requirements under NYC Building Code …


Resilience For Whom? A Study In Pathways And Production Of Unequal Risk In The Rockaways, Aaryan M. Nair Jan 2026

Resilience For Whom? A Study In Pathways And Production Of Unequal Risk In The Rockaways, Aaryan M. Nair

Publications and Research

This paper investigates how climate adaptation policies in the Rockaway Peninsula of New York City produce unequal outcomes despite their ostensibly neutral design, framing resilience as an environmental and climate justice problem. Situated within a landscape marked by stark socioeconomic disparities, aging housing stock, and high exposure to coastal flooding, the study demonstrates that existing adaptation strategies—centered on uniform technical standards, insurance frameworks, and large-scale coastal infrastructure—systematically advantage actors with greater financial and institutional capacity while leaving low-income residents, particularly renters, disproportionately vulnerable.

The analysis identifies three core dynamics underlying this “unequal-by-design” resilience regime: (1) the stratified feasibility of compliance …


All Games Have Equilibria, M. Ali Khan, Arthur Paul Pedersen, Maxwell B. Stinchcombe Jan 2026

All Games Have Equilibria, M. Ali Khan, Arthur Paul Pedersen, Maxwell B. Stinchcombe

Publications and Research

Research on Nash equilibrium existence for infinite games has grown into a patchwork of technical preconditions and counterexamples. This paper presents a unified program in equilibrium theory by revising the predominant model of mixed strategies based on countable additivity. A game is specified by a nonempty set of players and, for each player, a nonempty action set and a bounded von Neumann-Morgenstern utility function. Every such game is shown to admit a Nash equilibrium in finitely additive mixed strategies. In addition, the equilibrium correspondence for any such game is shown to be nonempty, compact-valued, and upper hemicontinuous, and the same …


Case Series Of Nizon-Isidor Syndrome By Heterozygous Variants In Med12l With Further Evidence Of Mitotic Instability In One Case With Diploid-Triploid Mosaicism, Russell Stewart, Kimberly M Ezell, Deanna S Bell, Brian Corner, Ashley Mcminn, Joy D Cogan, Rizwan Hamid, Lynette Rives, John A Phillips, Nina Paddu, Gitanjali Srivastava, Ronit Marom, Farah A Ladha, Claudia Soler-Alfonso, Rachel Franciskovich, Mary Koziura, Sumit Pruthi, Gabriele Richard, Christina B Sheedy, Undiagnosed Diseases Network, Thomas Cassini Jan 2026

Case Series Of Nizon-Isidor Syndrome By Heterozygous Variants In Med12l With Further Evidence Of Mitotic Instability In One Case With Diploid-Triploid Mosaicism, Russell Stewart, Kimberly M Ezell, Deanna S Bell, Brian Corner, Ashley Mcminn, Joy D Cogan, Rizwan Hamid, Lynette Rives, John A Phillips, Nina Paddu, Gitanjali Srivastava, Ronit Marom, Farah A Ladha, Claudia Soler-Alfonso, Rachel Franciskovich, Mary Koziura, Sumit Pruthi, Gabriele Richard, Christina B Sheedy, Undiagnosed Diseases Network, Thomas Cassini

Faculty, Staff and Students Publications

Nizon-Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7-year-old female who presented with developmental delay, right-leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin pigmentation, sectoral iris hypopigmentation, dysphagia, periventricular nodular heterotopia, seizures, morbid obesity, and a pelvic kidney. Genome sequencing (GS) revealed a MED12L variant, NM_053002.5:c.3559+2T>G. Both computational models and transcriptomic analysis confirmed that this variant induced splice loss of MED12L exon 25. Probands 2 and 3 presented with overlapping phenotypes of developmental delay; sequencing …


Emancipatory Research In Social Work: What Does Critical Realism Offer?, Shajimon Peter, Lynne Soon Chean Park, Liz Beddoe Jan 2026

Emancipatory Research In Social Work: What Does Critical Realism Offer?, Shajimon Peter, Lynne Soon Chean Park, Liz Beddoe

Research outputs 2022 to 2026

Summary: Critical realism offers a promising philosophical framework for emancipatory research in social work. Emancipatory research recognizes that people experience multiple realities and necessitates an inclusive participatory approach. However, these experiences are shaped by powers inherent in objectively existing structures, systems, and processes that must be identified and addressed for true emancipation. This theoretical article suggests a critical realism-informed methodology for emancipatory social work research. Findings: The critical realist framework acknowledges a stratified ontology and relativist epistemology that recognizes both subjective experiences and objective structures, bridging the subject–object binary created by objectivist and constructivist approaches. This allows for a radical …


Young People’S Likelihood Of Intervention To Nonconsensual Touching In Nightlife Settings: Interactions Of Gender, Relationship To The Bystander, And The Recipient’S Reaction, Aimee Rose Wrightson-Hester, Maria M. Allan, Alfred Allan Jan 2026

Young People’S Likelihood Of Intervention To Nonconsensual Touching In Nightlife Settings: Interactions Of Gender, Relationship To The Bystander, And The Recipient’S Reaction, Aimee Rose Wrightson-Hester, Maria M. Allan, Alfred Allan

Research outputs 2022 to 2026

Nonconsensual sexual behaviors that occur in nightlife settings pose unique policy challenges and encouraging bystander behavior (i.e., either to stop the actor or help the recipient; nonemotive words used to avoid priming participants) might be an effective way to prevent these behaviors. Few researchers, none Australian, have undertaken quantitative studies to identify factors that influence bystanders’ behavior in nightlife settings and the interactions between them. Australian participants (n= 332, 56% women) read eight vignettes depicting an incident where an actor grabbed the buttocks of a recipient, in which we manipulated the actor and recipient’s gender; relationship to the bystander; recipient …


School Library Professionals’ Perspectives On Current And Future Workforce Challenges, Margaret Kristin Merga, Saiyidi Mat Roni Jan 2026

School Library Professionals’ Perspectives On Current And Future Workforce Challenges, Margaret Kristin Merga, Saiyidi Mat Roni

Research outputs 2022 to 2026

While school library professionals work across many nations, supporting student learning and wellbeing, there is limited current research capturing shared issues faced by this educational workforce. The International School Library Workforce Survey collected insights from 971 respondents across 63 countries derived from analysis of both quantitative and qualitative data. Findings suggest that in an international context, school library professionals are experiencing notable issues that impact upon their morale and their ability to enact their professional roles. Respondents were more likely to disagree then agree that school library professionals were typically valued in their country. While the vast majority of respondents …


Crisis Planning Intentions Among Hotel Managers: What Have We Learned From The Covid-19 Pandemic?, Feliani Tjong, Edmund Goh, Violetta Wilk Jan 2026

Crisis Planning Intentions Among Hotel Managers: What Have We Learned From The Covid-19 Pandemic?, Feliani Tjong, Edmund Goh, Violetta Wilk

Research outputs 2022 to 2026

This study investigates the motivational factors which influence future crisis planning intentions, by utilising the Theory of Planned Behaviour (TPB) as the underlying theoretical framework. This research focuses on understanding the attitudes, subjective norms, and perceived behavioural control of hotel managers’ intentions regarding future crisis planning. To enhance the TPB model, the study incorporates two additional variables: perceived risk and past behaviour, thereby addressing previous calls to extend the TPB model. Employing a qualitative methodology, semi-structured interviews (n = 21) were conducted with hotel managers who worked at government-appointed quarantine hotels in Australia during the COVID-19 pandemic. Thematic analysis was …


Driving Factors And Spatio-Temporal Evolution Of Tourist Accident Clusters In Chinese Outbound Tourism, Chaowu Xie, Kun Zhang, Jiangchi Zhang, Songshan Huang Jan 2026

Driving Factors And Spatio-Temporal Evolution Of Tourist Accident Clusters In Chinese Outbound Tourism, Chaowu Xie, Kun Zhang, Jiangchi Zhang, Songshan Huang

Research outputs 2022 to 2026

The clustering of tourist accidents is a critical yet underexplored area of research. This study employs cluster theory and safety system theory to develop a comprehensive measurement tool for analysing tourist accident clusters, examining their spatiotemporal evolution patterns, and identifying the driving mechanisms from a holistic destination perspective. By analysing accident records of Chinese outbound tourists across 48 countries from 2011 to 2019, the findings reveal a reduction in disparities among tourist accident clusters (α-convergence effect) and a fluctuating trend over time. Spatial autocorrelation analysis identifies four distinct spatial distribution patterns: low-low (L-L), high-low (H-L), high-high (H-H), and low-high (L-H). …


Nation, Nature And Childhood In Five Curricula: Towards Earthly Education, Zsuzsa Millei, Katarzyna Gawlicz, Lucy Hopkins, Camilla Eline Andersen, Danielle Ekman Ladru Jan 2026

Nation, Nature And Childhood In Five Curricula: Towards Earthly Education, Zsuzsa Millei, Katarzyna Gawlicz, Lucy Hopkins, Camilla Eline Andersen, Danielle Ekman Ladru

Research outputs 2022 to 2026

This article explores the relations between nation, nature and childhood in five early childhood education curricula in the Nordic, post-socialist and settler-colonial states with the focus on the role education plays in the face of the climate crisis. The authors identify three interconnecting themes in which nation, nature and childhood are entangled in these curricula: 1) national nature as an object of learning; 2) nature and home/birth land and Country; and 3) stewardship for national nature. Exploring these themes from the perspective of alternative pedagogies developed to address the child–nature relations during the Anthropocene, the authors argue that these notions …


Managing Human Sources: Identification And Management Of Motivation, Tiffany Mckenzie, Pamela Henry, Nikki Rajakaruna Jan 2026

Managing Human Sources: Identification And Management Of Motivation, Tiffany Mckenzie, Pamela Henry, Nikki Rajakaruna

Research outputs 2022 to 2026

Human Source management is a critical function of intelligence and evidence collection by law enforcement and intelligence agencies across the world. Understanding the motivations of Human Sources is key to gaining high intelligence yields. Yet research which explores Human Source motivation, from a handler’s perspective, is limited. Even more limited is research which considers how motivation is identified and managed by law enforcement agencies across the course of a Human Source’s engagement with an agency. This research explores the experiences and perceptions of Human Source handlers from two Australian law enforcement agencies via semi-structured interviews (N = 17). Handlers highlighted …


Embodying Policy Work: An Exploration Of Contexts, Actions And Meanings Towards New Possibilities For Physical Education Teacher Education (Pete), Victoria Evans, David Aldous, Dawn Penney Jan 2026

Embodying Policy Work: An Exploration Of Contexts, Actions And Meanings Towards New Possibilities For Physical Education Teacher Education (Pete), Victoria Evans, David Aldous, Dawn Penney

Research outputs 2022 to 2026

This theoretical paper presents a heuristic framework that is directed towards transformative thinking and practices in Physical Education Teacher Education (PETE). The research focus and direction, embodying policy work, applies and extends Bernstein’s concepts of the pedagogic and corporeal device to offer new directions for inquiry and explore the considerations these raise for PETE professionals and their practices. The paper affirms the importance of policy work in PETE, while recognising a need for more nuanced and critical understandings of the complex interrelationships between contexts and actions, and the potential meanings generated and ascribed to different forms of policy work and …


Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang Jan 2026

Gastronomy Tourism Destinations: Developing A Scale To Measure Tourists’ Perceived Attributes, Ganghua Chen, Jingmei Xu, Songshan (Sam) Huang

Research outputs 2022 to 2026

Purpose: This study emphasizes the growing significance of destination attributes in shaping the experiences and behaviours of gastronomy and culinary tourists. Understanding both core and complementary attributes of a gastronomy tourism destination is crucial for its sustainable development. However, there is a lack of a reliable measurement for tourists’ perceived attributes of gastronomy tourism destinations (PAGTD). Therefore, the purpose of this study is to develop a scale to measure tourists’ PAGTD. Design/methodology/approach: The study systematically followed the scale development and validation process, using three samples (Sample 1, n = 200; Sample 2, n = 204; and Sample 3, n = …


Australian University Websites As Colonialities Of Gender, Emily M. Gray, Ampersand Pasley, Emma Fishwick, Mindy Blaise, Jacqueline Ullman, Maria Delaney Jan 2026

Australian University Websites As Colonialities Of Gender, Emily M. Gray, Ampersand Pasley, Emma Fishwick, Mindy Blaise, Jacqueline Ullman, Maria Delaney

Research outputs 2022 to 2026

This paper offers analysis of the first phase of a research project, Understanding and Addressing Everyday Sexisms in Australian Universities. This phase involved a critical content analysis of all 39 of Australia’s public university websites, focusing on how they represent gender, absences in relation to gender and the navigability of the websites in relation to gender equity policy. Drawing on Maria Lugones’s colonialities of gender, this paper demonstrates how university websites have the potential to reproduce or renegotiate inherited institutional everyday sexisms and broader gender inequities. Themes of reconfiguring acceptable gendering, conspicuous absences, and in-built obscurity that emerged from this …


The Role Of Games In Hospitality Management Education, Arghavan Hadinejad, Samira Zare Jan 2026

The Role Of Games In Hospitality Management Education, Arghavan Hadinejad, Samira Zare

Research outputs 2022 to 2026

Building upon game-based learning, this study compares hospitality students’ cognition, metacognition, engagement, satisfaction, and performance in a course across two academic terms at an Australian university. One term featured teaching content without any games while the second term incorporated gamification. A quasi-experimental design was used in which surveys, interviews and students’ evaluation reports were utilized. Students demonstrated more favorable cognitive thoughts, and higher levels of engagement and satisfaction in the gamified course. Students’ performance in assessments across the two courses as well as their metacognition were found to be similar. This study presents a game effectiveness matrix with Kahoot as …


Ensuring That Marginalized Young People Feel Welcome, Understood, And Empowered In Health Services: A Qualitative Examination Of The Service Needs Of Aboriginal Lgbtqa+ Young People, Shakara Liddelow-Hunt, Ashleigh Lin, Yael Perry, Braden Hill, Bep Uink Jan 2026

Ensuring That Marginalized Young People Feel Welcome, Understood, And Empowered In Health Services: A Qualitative Examination Of The Service Needs Of Aboriginal Lgbtqa+ Young People, Shakara Liddelow-Hunt, Ashleigh Lin, Yael Perry, Braden Hill, Bep Uink

Research outputs 2022 to 2026

A lack of appropriate care and discrimination in healthcare settings likely compounds the existing risks to mental health and well-being for Aboriginal and Torres Strait Islander lesbian, gay, bisexual, trans, queer/questioning, and asexual (LGBTQA+) young people. The current study contributes findings from Aboriginal LGBTQA+ young people’s perspectives on their health service needs and preferences. Data consists of qualitative interviews and focus groups with N = 14 Aboriginal LGBTQA+ young people aged 14–25 years in Boorloo (Perth), Western Australia. The data was analyzed using reflexive thematic analysis. Analysis identified three major themes: (1) Unmet need for “whole self” care, (2) Communicating …


Antecedents Of Emergency Services’ Street Level Bureaucrats’ (Slbs) Delivery Of Public Value: An Exploratory Study, Yvonne Brunetto, Ben Farr-Wharton, Aglae Hernandez Grande, Fleur Sharafizad, Matthew Richman Jan 2026

Antecedents Of Emergency Services’ Street Level Bureaucrats’ (Slbs) Delivery Of Public Value: An Exploratory Study, Yvonne Brunetto, Ben Farr-Wharton, Aglae Hernandez Grande, Fleur Sharafizad, Matthew Richman

Research outputs 2022 to 2026

Street Level Organisations (SLOs) determine the Psychosocial Safety Climate (PSC) in their workplaces and we examine pathways from SLBs’ PSC and Public Service Motivation (PSM) to discretionary power, work stress, wellbeing and the subsequent delivery of public value. The structural equation modelling results from 195 Australian police, fire, ambulance, and emergency services workers indicate that PSC had a more significant role in explaining SLBs’ delivery of public value compared with PSM. The implication is that SLOs’ management must ensure psychosocially safe and supportive workplaces conducive to building SLBs’ wellbeing, because that is the pathway for delivering public value.


Care-Full Climate Justice Organising, Kylie Wrigley Jan 2026

Care-Full Climate Justice Organising, Kylie Wrigley

Research outputs 2022 to 2026

Feminist, Indigenous, and disability theories and activisms have long called for more attention to care–both as an ethic and practice–in response to environmental and social issues. Although care work is vital for collective survival, it is relatively devalued and trivialised in society and under-examined in climate justice research. Emerging critical research suggests that care work is central to how climate justice communities understand and respond to climate change and interlocking structural violences. Yet, there is limited climate justice scholarship that attends to the intersections of care and climate movements. At this juncture, this article draws on empirical reflections from a …


Christianity As Coping Mechanisms For Migrants With Mental Health Challenges In Australia: Social Work Implications, Obed Adonteng-Kissi, Nnaemeka Meribe, Kathomi Gatwiri, Lillian Mwanri, Agness Tembo, Frank Darkwa Baffour, Edith N. Botchway-Commey, Aunty Kerrie Doyle, David Chisanga, Ahmed A. Moustafa, Uchechukwu Levi Osuagwu Jan 2026

Christianity As Coping Mechanisms For Migrants With Mental Health Challenges In Australia: Social Work Implications, Obed Adonteng-Kissi, Nnaemeka Meribe, Kathomi Gatwiri, Lillian Mwanri, Agness Tembo, Frank Darkwa Baffour, Edith N. Botchway-Commey, Aunty Kerrie Doyle, David Chisanga, Ahmed A. Moustafa, Uchechukwu Levi Osuagwu

Research outputs 2022 to 2026

Christian religion may be a powerful resource that can serve as a coping mechanism to resolve challenges and provide comfort to African migrants confronted with mental health challenges. We aimed to explore the coping strategies among African migrants in Australia. We undertook semi-structured interviews online with 11 participants with African backgrounds, comprising six mental health clinicians and five migrant service users living in Australia for at least the past 12 months. Literature exploring religious coping mechanisms, social support and acculturation was drawn on. The interviews were undertaken online via Teams, WhatsApp call, and zoom with participants whom we recruited through …


Stakeholder Perceptions Of The Feasibility Of E-Portfolio-Based Assessment Of Physical Literacy In Primary Health And Physical Education, Jaxon Hogan, Dawn Penney, Eibhlish O’Hara, Joseph Scott Jan 2026

Stakeholder Perceptions Of The Feasibility Of E-Portfolio-Based Assessment Of Physical Literacy In Primary Health And Physical Education, Jaxon Hogan, Dawn Penney, Eibhlish O’Hara, Joseph Scott

Research outputs 2022 to 2026

Background: Physical literacy (PL) is widely acknowledged as an integral component of high-quality physical education programmes. However, what constitutes appropriate assessment of PL remains a contested issue. This study drew on Whitehead’s conceptualisation of PL as a lifelong journey and investigated how primary school teachers can support students’ PL learning through innovative and engaging assessment methods. The study specifically examined the feasibility of using e-portfolios to facilitate quality PL learning and quality assessment in Physical Education (PE), from different stakeholder perspectives. Methods: This interpretive study employed a qualitative design and methods to investigate aspects of feasibility with three purposive participant …


From Perspectival Myopia To Professional Transformation: An Autoethnographic Retrospection Of A High School Principal From Nepal, Shankar Dhakal, Geoffrey W. Lummis, Andrew Jones Jan 2026

From Perspectival Myopia To Professional Transformation: An Autoethnographic Retrospection Of A High School Principal From Nepal, Shankar Dhakal, Geoffrey W. Lummis, Andrew Jones

Research outputs 2022 to 2026

This paper presents a re-storied account of my (lead author) decade-long (2007–2017) professional journey as a high school principal in diverse educational settings in Nepal. Using an autoethnographic approach, I have theorized my leadership transformation approaches through professional storytelling, employing critical reflexivity to trace intimate leadership experiences where authoritarian approaches to leadership, disparities, and inequalities in schools run rampant. My perspectival myopia, professional vulnerabilities, and the discrepancies between my leadership ideals and behaviors resulted in issues such as perceptions of disengagement, underperformance, and dissatisfaction on the receiving end, prompting me to contemplate professional transformation. While outlining several significant steps and …


Comparative Analysis Of Ev-Charging Converters Using Silicon Carbide Mosfets And Silicon Igbt’S, Muhammad A. Kahn Jan 2026

Comparative Analysis Of Ev-Charging Converters Using Silicon Carbide Mosfets And Silicon Igbt’S, Muhammad A. Kahn

Electrical Engineering Theses

The rapid expansion of electric vehicle (EV) charging infrastructure has increased the demand for efficient and reliable power electronic converters. Semiconductor device selection is critical to system performance, influencing efficiency, power density, and reliability. This thesis presents a comparative analysis of Silicon (Si) Insulated Gate Bipolar Transistors (IGBTs) and Silicon Carbide (SiC) MOSFETs in a representative EV charging converter, with emphasis on electrical performance and thermal behavior under identical operating conditions.

The research employs PLECS (Plexim) and electro-thermal simulation models to accurately characterize device and system interactions. The converter configuration consists of a grid-connected voltage source inverter (VSI) that maintains …


The Manifestation Of Antihaitianismo In Abinader’S Dominican Political Atmosphere, Isabella Alcantara Jan 2026

The Manifestation Of Antihaitianismo In Abinader’S Dominican Political Atmosphere, Isabella Alcantara

FCRH Honors Program Theses

In the past decade, Haitian migration has become central to Dominican political discourse. This shift is particularly evident under President Luis Abinader’s administration, which has overseen a sharp increase in restrictive border enforcement and citizenship measures targeting Haitian migrants fleeing escalating humanitarian crises. While existing scholarship on Dominican nationalism highlights the historical role of antihaitianismo in shaping exclusionary state practices, less attention has been paid to how contemporary elite rhetoric reproduces these dynamics in more indirect, coded ways. Drawing on theories of symbolic politics and securitization, this study examines how state discourse constructs Haitian migrants within national narratives. It asks: …


The Long Life Of Illumination: How Medieval Manuscripts Shaped Modern Print Culture, Malena Sullivan Jan 2026

The Long Life Of Illumination: How Medieval Manuscripts Shaped Modern Print Culture, Malena Sullivan

FCRH Honors Program Theses

Design is everywhere in our lives, from product and book layouts to advertisements and the web. Design packages information into visually appealing formats which grab attention and relate an easily understood message. Through fonts, illustrations, patterns, and color, good design does more than just convey information. Rather, it is an art form in itself that has the power to stay within the viewer’s imagination through impactful visuals. The act of designing is a creative process, but also one that often borrows from the past. Before printing was widely adopted in Europe in the fifteenth century, books were written out and …


Dual Targeting Of Amrc12 And Malassezia Globosa Disrupts Myc Liquid Condensates-Driven Nuclear Pore Complex Biogenesis In Neuroblastoma, Anpei Hu, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Shunchen Zhou, Bosen Zhao, Jiaying Qu, Xiaojing Wang, Liduan Zheng, Qiangsong Tong Jan 2026

Dual Targeting Of Amrc12 And Malassezia Globosa Disrupts Myc Liquid Condensates-Driven Nuclear Pore Complex Biogenesis In Neuroblastoma, Anpei Hu, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Shunchen Zhou, Bosen Zhao, Jiaying Qu, Xiaojing Wang, Liduan Zheng, Qiangsong Tong

Faculty, Staff and Students Publications

Rationale: Neuroblastoma (NB) is a predominant extra-cranial malignancy in childhood, while molecular drivers of its progression and effective treatment strategies have yet to be clarified.

Methods: RNA sequencing was performed to identify transcriptional regulators and corresponding target genes. To explore the biological effects and underlying mechanisms of these regulators, a comprehensive methodology was utilized, encompassing chromatin immunoprecipitation, dual-luciferase reporter assay, qRT-PCR, western blot, alongside gene over-expression and silencing techniques, co-immunoprecipitation, and mass spectrometry. The MTT assay, soft agar colony formation, Matrigel invasion, and nude mouse xenograft models were applied to assess oncogenic properties. Patient survival was analyzed using the log-rank …


Findings And Recommendations From The State Of The Art (Sota) Conference On Nursing Research To Improve Veteran Outcomes, Amelia E Schlak, Sarah Krein, Laura A Petersen, David Atkins, Catherine Battaglia, Elizabeth Burkhart, Renee Colsch, Marguerite Daus, Heather Gilmartin, Nipa Kamdar, Melissa Knox, Ann Kutney-Lee, Christine M Olney, Kathryn Rugen, Tracy Weistreich, Sheila Cox Sullivan, On Behalf The Nursing Sota Planning Committee Jan 2026

Findings And Recommendations From The State Of The Art (Sota) Conference On Nursing Research To Improve Veteran Outcomes, Amelia E Schlak, Sarah Krein, Laura A Petersen, David Atkins, Catherine Battaglia, Elizabeth Burkhart, Renee Colsch, Marguerite Daus, Heather Gilmartin, Nipa Kamdar, Melissa Knox, Ann Kutney-Lee, Christine M Olney, Kathryn Rugen, Tracy Weistreich, Sheila Cox Sullivan, On Behalf The Nursing Sota Planning Committee

Faculty, Staff and Students Publications

The Veterans Health Administration (VHA), the largest employer of nurses in the United States, has more than 120,000 nursing personnel providing care to over 9 million Veterans across diverse settings. Despite nursing's central role in delivering and sustaining care, research on strengthening the nursing workforce and optimizing nursing practice has remained underdeveloped in VHA. To address this gap, VHA's Office of Research and Development, in partnership with the Office of Nursing Services, convened a State of the Art (SOTA) conference in November 2023 focused on nursing. The Nursing SOTA brought together nurses, researchers, operational leaders, and other stakeholders to review …


Assessment Of In-Frame Indel Variants In An Unsolved Cohort Of Inherited Retinal Diseases Using Machine Learning, David E Rauch, Meng Wang, Muhammad Jafar Hussain Hafiz, Daniel C Brock, Yumei Li, Molly Marra, Mark E Pennesi, Paul Yang, Everett Lesley, Irma Lopez, Robert Koenekoop, Edward Ryan Collantes, Joanne Bolinao, Rui Chen Jan 2026

Assessment Of In-Frame Indel Variants In An Unsolved Cohort Of Inherited Retinal Diseases Using Machine Learning, David E Rauch, Meng Wang, Muhammad Jafar Hussain Hafiz, Daniel C Brock, Yumei Li, Molly Marra, Mark E Pennesi, Paul Yang, Everett Lesley, Irma Lopez, Robert Koenekoop, Edward Ryan Collantes, Joanne Bolinao, Rui Chen

Faculty, Staff and Students Publications

The standard for in silico pathogenicity prediction of in-frame insertions and deletions (indels) is less established compared to other types of variations. We aimed to systematically assess the performance of in silico machine learning (ML) tools on a patient cohort with inherited retinal diseases (IRDs). The performance of four ML tools (CADD, FATHMM-indel, VEST4, and MetaRNN-indel) was compared. Among them, MetaRNN-indel showed the best overall results. MetaRNN-indel was then applied to 1013 unsolved IRD patients, identifying two likely pathogenic causal variants in two unrelated IRD patients by confirming clinical phenotypes. Hence, our findings indicate that reliable prediction of the pathogenicity …


Strategies And Challenges For The Recruitment Of Young Healthy Participants In The Dietary Approaches To Longevity And Health (Dial Health) Pilot Trial, Hannah E Cabre, Courtney M Peterson, Gareth R Dutton, Kimberly L Drews, Stephanie T Broyles, Robert Dubin, Laura Q Rogers, Catherine Champagne, Dennis T Villareal, Daniel S Hsia, Leanne M Redman, Corby K Martin Jan 2026

Strategies And Challenges For The Recruitment Of Young Healthy Participants In The Dietary Approaches To Longevity And Health (Dial Health) Pilot Trial, Hannah E Cabre, Courtney M Peterson, Gareth R Dutton, Kimberly L Drews, Stephanie T Broyles, Robert Dubin, Laura Q Rogers, Catherine Champagne, Dennis T Villareal, Daniel S Hsia, Leanne M Redman, Corby K Martin

Faculty, Staff and Students Publications

Background: Understanding the impact of nutrition on human aging requires long-term trials in young, healthy, unmedicated adults. As part of the Dietary Approaches for Longevity and Health (DiAL Health) pilot project, we evaluated strategies for recruiting this population for aging-related dietary intervention studies.

Methods: We analyzed recruitment costs to enroll 70 participants (ages 25-49, BMI 22.0-29.9 kg/m2) across two DiAL Health sites and used NHANES data (2017-March 2020) to estimate the proportion of U.S. adults meeting partial trial eligibility. Additionally, a formative study surveyed 492 U.S. adults (≥18 years) to assess interest in aging-focused dietary trials.

Results: Of 2049 applicants …


Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso Jan 2026

Sewers To Solutions: A Guide To Wastewater Pathogen Monitoring, Justin R Clark, Anthony W Maresso

Faculty, Staff and Students Publications

Wastewater-based epidemiology (WBE) is the analysis of wastewater to detect pathogen levels or activity for public health awareness or action. Pioneered in the 1940s, WBE underwent a resurgence during the COVID-19 pandemic, providing important information about number of cases, outbreaks, and seasonal impact. With advancements in detection technologies and growing interest in environmental surveillance, WBE is poised to become a standard practice in public health monitoring. Here, we provide an overview of the current state of the art of pathogen WBE, including methods of molecular detection, analysis of wastewater data, real-world applications and programs, public health interventions, and benefits and …


Lysine Demethylase 4a Is A Centrosome-Associated Protein Required For Centrosome Integrity And Genomic Stability, Pratim Chowdhury, Xiaoli Wang, Richard I Han, Manga Motrapu, Ashley G Boice, Yuya Nakatani, Sofia Vargas-Hernandez, Julia F Love, Claude Chew, Sandra L Grimm, Dereck Mezquita, Frank M Mason, Elisabeth D Martinez, Cristian Coarfa, Cheryl L Walker, Anna-Karin Gustavsson, Ruhee Dere Jan 2026

Lysine Demethylase 4a Is A Centrosome-Associated Protein Required For Centrosome Integrity And Genomic Stability, Pratim Chowdhury, Xiaoli Wang, Richard I Han, Manga Motrapu, Ashley G Boice, Yuya Nakatani, Sofia Vargas-Hernandez, Julia F Love, Claude Chew, Sandra L Grimm, Dereck Mezquita, Frank M Mason, Elisabeth D Martinez, Cristian Coarfa, Cheryl L Walker, Anna-Karin Gustavsson, Ruhee Dere

Faculty, Staff and Students Publications

Centrosomes play a fundamental role in nucleating and organizing microtubules in the cell and are vital for faithful chromosome segregation and maintenance of genomic stability. Loss of structural or functional integrity of centrosomes causes genomic instability and is a driver of oncogenesis. Here we identify lysine demethylase 4A (KDM4A), an epigenetic 'eraser' of chromatin methyl marks, as a centrosome-localized protein, visualized at the nanometer-scale resolution. We additionally uncovered that KDM4A demethylase enzymatic activity is required to maintain centrosome homeostasis and integrity; a previously unknown functionality unlinked to altered expression of genes regulating centrosome number. We find that KDM4A interacts with …