Digital Commons Network^™

Implanting Microelectrode Arrays In The Bottom Of The Central Sulcus Targeting Somatosensory Area 3a For Restoration Of Proprioception

Faculty, Staff and Student Publications

Objective: The long-term goal of this work is to develop a sensorimotor brain-machine interface (BMI) in which intended movements are decoded from the motor cortex and proprioceptive feedback is delivered via intracortical microstimulation of Brodmann's area 3a. A vital step toward this goal is to demonstrate in rhesus macaques a novel surgical approach for the precise and safe implantation of custom-length microelectrode arrays into area 3a at the bottom of the central sulcus.

Methods: Preoperative planning combined high-resolution 7-T MR and CT imaging to generate 3D models of the cortices of 2 subjects. These models were used to fabricate 3D-printed …

2026 February, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for February of 2026.

Design And Implementation Of An Aapm Volunteer Database For Advancing Global Medical Physics Initiatives., Teh Lin, Minsun Kim, Courtney Morrison, Jiahan Zhang, Kevin Little, Yan-Hong Xin, Michael Woodward, Peter Sandwall, Eun Young Han

Oncology Articles

PURPOSE: The purpose of this study is to assess American Association of Physicists in Medicine (AAPM) members' availability to volunteer, share their expertise, and promote global collaboration in medical physics by partnering with international colleagues who seek support in strengthening their medical physics practice.

METHODS: The questionnaire was administered to AAPM members to assess their willingness to volunteer, preferred engagement modalities, and availability for different types of volunteer activities. The questionnaire was integrated into the AAPM member profile and covered therapy, diagnostic, and nuclear medicine disciplines, capturing participants' visiting preferences and expertise in teaching and training. Respondents were categorized based …

Acute Otitis Media: Antibiotic Length, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Optical Fiber Sensors Using Vernier Effect In Cascaded Fiber Interferometers, Zhouchen Wang

Dissertations

The optical Vernier effect has emerged as a powerful tool to enhance the sensitivity of optical fiber interferometer-based sensors, opening new opportunities for developing highly sensitive fiber sensing systems. Optical fiber interferometric sensors based on the Vernier effect are widely used for various applications due to their ultra-compact size, high sensitivity, immunity to electromagnetic interference, electrical isolation, resistance to harsh environments, flexibility, multiplexing capability, and remote operation. The aim of this doctoral thesis was to gain a deeper fundamental understanding of the Vernier effect in optical fiber structures and to develop and investigate a series of novel Vernier effect optical …

Stimuli-Responsive Chemotherapy For Glioblastoma: Sequence-Dependent Synergy Of Cold Atmospheric Plasma And Ultrasound With Cationic Lipo-Doxo, Alessandro Cazzolla

Theses

Glioblastoma (GBM) is an aggressive, infiltrative astrocytic tumour in which pharmacotherapy remains constrained by the blood-brain barrier (BBB) and the heterogeneously altered blood brain tumour barrier, with additional limitations imposed by active efflux and the complexity of the tumour microenvironment. In this setting, externally addressable strategies that modulate transport and uptake at the site of disease are required. A stimuli-responsive chemotherapy platform was developed in which Lipo-DOXO was combined with two non-invasive physical modalities, low-frequency ultrasound (US) and cold atmospheric plasma (CAP), to enhance intratumoural delivery while limiting off-target effects. Liposomes were produced by thin-film hydration followed by a controlled, …

Market Culture And Innovation Acceptance In Fire Safety Products: The Moderating Role Of Perceived Market Regulation, Xu Zhang

Dissertations and Theses Collection (Open Access)

Against the backdrop of continuously rising global fire safety standards and ongoing technological iteration in fire protection products, whether innovative fire protection products can be effectively accepted by the market has become a critical issue influencing the returns on firms’ innovation investments and the high-quality development of the industry. Existing studies have predominantly explored innovation diffusion mechanisms from the perspectives of technological attributes or organizational factors, while paying relatively limited attention to market culture as a contextual factor, as well as to the differentiated role that government regulation may play in this process. Based on this, this study takes institutional …

Thermodynamic Analysis Of Metal Segregation In Two Metal Boride-Carbide Ceramics Containing V With Cr, Hf, Ti, Or Zr, Ana C. Feltrin, Simon Divilov, Gregory E. Hilmas, Stefano Curtarolo, William G. Fahrenholtz

Materials Science and Engineering Faculty Research & Creative Works

Dual-phase carbide-boride ceramics in different vanadium-Me (Me = Cr, Hf, Ti, and Zr) binary systems were synthesized by boro/carbothermal reduction under stoichiometric and carbon-deficient conditions and densified by spark plasma sintering. Thermodynamic analysis was used to evaluate the influence of composition on the phase stability and metal segregation between phases, along with the resulting effects on microstructure and hardness. Pairing vanadium with Group IV elements (Hf, Ti, and Zr) consistently formed one boride and one carbide phase, while the Cr-V system formed a monoboride phase and a carbon-deficient carbide. Metal segregation trends depended on composition. Vanadium preferentially segregated to the …

Are Cities Losing Innovation Advantages? Online Versus Face-To-Face Interactions, Ruben Gaetani, Naqun Huang, Jing Li, Yanmin Yang

Research Collection School Of Economics

How did COVID-19 affect the innovation advantages of dense locations? Using data on the universe of U.S. patent applications, we find that the density premium in the production of novel inventions declined by 18.5%-22.9% in 2020-2021 relative to its pre-pandemic level. Smartphone data on local mobility suggest that the drop in the frequency of local interactions can explain a significant portion of this effect. While COVID-19 resulted in a temporary setback in the innovation advantages of dense locations, the role of urban density in facilitating the exchange and recombination of ideas is unlikely to be persistently replaced by online communication.

Removed: When Taxi Drivers Meet Dynamic Pricing: A Lesson From Singapore's Justgrab Program, Shih-Fen Cheng, Wen-Tai Hsu, Jing Li

Research Collection School Of Economics

This paper studies how dynamic pricing influences taxi drivers’ behaviors using a unique event, the inception of the JustGrab program in Singapore in 2017, which introduces dynamic pricing to some, but not all, taxi drivers. This is the first time in history that traditional taxi drivers have access to dynamic pricing. Using data covering the universe of taxi trips before and after the inception of JustGrab, we find that there is spatial reallocation that directs more taxi drivers to the previously less-served areas, that there is also a temporal reallocation that directs more taxi drivers to rush hours, as well …

Final 2022 Unreclaimed Sites Sampling: Ur-20 Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

G-Trac: Graph-Textual Representations Alignment For Cold-Start Recommendations, Li Yang Chang, Yuan Fang, Ming Feng Tsai, Chuan Ju Wang

Research Collection School Of Computing and Information Systems

The cold-start problem remains a significant challenge in recommendation systems, particularly for new users or unseen items with little to no historical data. Existing methods, including graph neural networks, often struggle in such scenarios. Inspired by the success of transformer models in natural language processing, we propose G-TRAC (Graph-Textual Representations Alignment for Cold-start Recommendations), a novel approach that integrates transformer-based textual modeling with graph neural networks. By effectively leveraging both textual and structural information, G-TRAC addresses cold-start challenges more effectively. Extensive experiments demonstrate its ability to enhance recommendation quality and generalize well across diverse scenarios.

Sit, Stay, And Teach: Exploring Teachers' Perceptions Of Facility Dogs' Impact On Stress And Retention, Dennis Powers

Graduate Student Dissertations, Theses, Capstones, and Portfolios

The teaching profession remains at a high level of workplace stress, a factor contributing to teacher burnout and turnover. The study examines how teachers in K-12 public education perceived that facility dogs might reduce stress, increase job satisfaction, and aid in teacher retention in public schools of a southeastern state. The study employed a qualitative, cross-sectional survey that was emailed to 112,546 educators from a LISTSERV request. A total of 1,242 individuals provided informed consent and completed the survey, which consisted of Likert-scale measurement items, open-ended questions, and an informational video inserted to achieve a common understanding of the facility …

The Comparator Argument In Trans-Healthcare Ban Cases, Craig Konnoth

UC Law Journal

As states have increasingly restricted gender affirming care for minors across the nation (reinforced by a recent Executive Order by President Trump), and though the Supreme Court ruled on one such state ban, a powerful argument has largely been overlooked. This argument emphasizes the fact that transgender minors are not alone in receiving gender affirming care. Cisgender minors also receive such care for precisely the same reasons as transgender minors— unwanted breast tissue development, undesired hair growth, unusual vocal development, and puberty onset. Indeed, cisgender children receive such care at higher numbers than trans children, and many of the medications …

Systemic Jurisdictional Ambiguity, Norman W. Spaulding

UC Law Journal

The purpose of jurisdictional rules is to provide reasonably clear signals about when a court does and does not have power over a case. Judging from the modern Supreme Court’s rules for determining jurisdiction, however, one would think jurisdictional rules need neither be clear nor consistent. From rules for determining standing, federal question jurisdiction, and personal jurisdiction to Erie doctrine and the power of Congress to create non-Article III courts—rules that affect the administration of justice in millions of cases every year—modern jurisdictional rules are notorious for their inconsistency and ambiguity. This level of ambiguity is remarkable given the zeal …

A Case Against Mass Deportation: The Japanese American Internment Camps And Recent Treatment Of Korematsu, Isaac Bloch

UC Law Journal

The large-scale deportation of non-citizens has become a preeminent policy issue. Unfortunately, executive curtailment of immigrant communities’ liberty is not without historical parallels. During World War II, federal officials sent individuals of Japanese descent to internment camps through a series of executive orders and military proclamations. Although attorneys in the Department of Justice believed aspects of these actions were unconstitutional at the time, the administration prevailed at the nation’s highest court. Can recognition of this past wrong aid challenges to contemporary immigration enforcement regimes? How do our courts formally account for the most egregious jurisprudential errors of the past, and …

Modernising Wills For A Smart Nation, Hang Wu Tang, Edward Ti

Research Collection Yong Pung How School Of Law

In a commentary, SMU Lee Kong Chian Professor of Law Tang Hang Wu and SMU Associate Dean (Undergraduate Curriculum and Teaching) and Associate Professor of Law Edward Ti highlighted that Singapore has digitalised almost everything around the will, but not the will itself. Prof Tang and Assoc Prof Ti noted that the current legislation insists that the will itself remains a paper ritual, which is not just an inconvenience but also risks Singapore’s competitiveness. They argued that Singapore should modernise without compromising on steps to prevent fraud and undue influence. They highlighted that the law should be modernised so that …

How Consistent Friendlike Conversation With Ai Companions Influences Our Attitudes And Perceptions Toward Ai: An Exploratory Experiment, Qi Hui Jerlyn Ho, Meilan Hu, Adalia Yin Hui Goh, Emma Jane Pragasam, Andree Hartanto

Research Collection School of Social Sciences

Despite skepticism and distrust in artificial intelligence (AI), it is increasingly integrated into daily life, with its potential benefits drawing interest. Yet little is known about the attitudinal and psychological effects of human–AI interactions, and whether consistent interactions with AI chatbots can change users’ attitudes and perceptions. Our within-subjects experiment (N = 52) investigated how five days of socially oriented, friendlike interactions with an AI chatbot, versus a journaling control, influenced changes in attitudes and perceptions of AI. Participants’ attitudes towards AI, trust, perceived empathy, anthropomorphism, animacy, likeability, perceived intelligence and safety, dependency, and exploratory well-being indicators were recorded. Results …

The Gains Do Not Make Up For The Losses: A Comprehensive Evaluation For Safety Alignment Of Large Language Models Via Machine Unlearning, Weixiang Zhao, Yulin Hu, Xingyu Sui, Zhuojun Li, Yang Deng, Yanyan Zhao, Bing Qin, Wanxiang Che

Research Collection School Of Computing and Information Systems

Machine Unlearning (MU) has emerged as a promising technique for aligning large language models (LLMs) with safety requirements to steer them forgetting specific harmful contents. Despite the significant progress in previous studies, we argue that the current evaluation criteria, which solely focus on safety evaluation, are actually impractical and biased, leading to concerns about the true effectiveness of MU techniques. To address this, we propose to comprehensively evaluate LLMs after MU from three aspects: safety, over-safety, and general utility. Specifically, a novel benchmark MuBench with 18 related datasets is first constructed, where the safety is measured with both vanilla harmful …

Recurrent Miller Fisher Syndrome: A Case Report, Larry Vernier, Griffin B. Gilmore, Kelsey Van Housen, Xiao C. Zhang

Department of Emergency Medicine Faculty Papers

INTRODUCTION: Guillain-Barré syndrome can manifest with progressive paralysis, requiring careful monitoring and treatment with steroids or intravenous (IV) immunoglobin. While this disease can be devastating and require intensive care unit level of care, there are few incidences of relapses.

CASE REPORT: A 67-year-old man with a past medical history of Miller Fisher syndrome variant of Guillain-Barré syndrome, with complete recovery, presented to the emergency department (ED) with ataxia, ophthalmoplegia, dysphonia, and ambulatory dysfunction. The patient noticed his neurologic symptoms after waking up, and he presented to the ED with physical examination positive for difficulty with upward gaze, mild right lower …

A Social Norm Perspective On Distorted Information In China, Zhe Li, Massimo Massa, Nianhang Xu, Hong Zhang

Research Collection Lee Kong Chian School Of Business

Can social norms give rise to distorted information in China? We observe that China’s leading social norm related to alcohol consumption and social drinking enhance earnings management. An analysis of toxic alcohol scandals supports a causal interpretation. Further evidence suggests that the influence of alcohol may come from the negative externality that it creates, which is propagated by corporate leaders and cannot be attenuated by market-oriented institutions. Our results reveal a social norm externality that may have important normative implications.

Are Less Hierarchical Firms Organized Around Stronger Cultures? Evidence From Big Data, Arianna Marchetti, Phanish Puranam

Research Collection Lee Kong Chian School Of Business

Research Summary: Are less hierarchical firms organized around stronger cultures instead? We analyze 1.5 million employee reviews on Glassdoor.com from 23,000 US-based firms, alongside data on managerial hierarchy estimated from 42 million professional social media profiles. Our findings confirm a negative association between managerial hierarchy and organizational culture strength. We explore two potential explanations for this association: Functional equivalence between the two, and culture fragmentation caused by managerial hierarchy. Multiple correlational tests show support for functional equivalence as a plausible explanation for the observed negative correlation. Our findings enhance our understanding of the complex relationships between organizational structure and culture …

The Distinctiveness Effect: How Cross-Country Dissimilarities Influence Governance Decisions, Ilya Cuypers, Gokhan Ertug, Niels G. Noorderhaven, Korcan Kavusan

Research Collection Lee Kong Chian School Of Business

Transaction cost theory is one of the most commonly used theories to explain how firms govern their economic activities. In the context of cross-border collaborations, transaction cost theory proposes that dissimilarities between the partners’ home countries, which constitute a key source of behavioral uncertainty, affect how collaborations are governed (i.e. whether firms opt for equity joint ventures or non-equity alliances). Although many firms are likely to face more than one dimension of dissimilarity—for example, in terms language and religion, as well as culture—studies in transaction cost theory typically focus on how each source of dissimilarity impacts governance choices independently, in …

New Asymptotics Applied To Functional Coefficient Regression And Climate Sensitivity Analysis, Qiying Wang, Peter C. B. Phillips, Ying Wang

Research Collection School Of Economics

A general asymptotic theory is established for sample cross moments of nonstationary time series, allowing for long-range dependence and local unit roots. The theory provides a substantial extension of earlier results on nonparametric regression that include near-cointegrated nonparametric regression as well as spurious nonparametric regression. Many new models are covered by the limit theory, among which are functional coefficient regressions in which both regressors and the functional covariate are nonstationary. Simulations show finite sample performance matching well with the asymptotic theory and having broad relevance to applications, while revealing how dual nonstationarity in regressors and covariates raises sensitivity to bandwidth …

Corrigendum To “Interim Rationalizable Implementation Of Functions” (Kunimoto T, Saran R, Serrano R (2024) Mathematics Of Operations Research 49(3):1791–1824), Takashi Kunimoto, Rene Saran, Roberto Serrano

Research Collection School Of Economics

This is the brief corrigendum to “Interim rationalizable implementation of functions” [Kunimoto T, Saran R, Serrano R (2024) Interim rationalizable implementation of functions. Math. Oper Res. 49(3):1791–1824].

Hyperglycemia, Receptor For Advanced Glycation End Products, And Small Airways Dysfunction In Asthma, Amrit Koirala, Cristian Coarfa, Meredith C Mccormack, Nicola A Hanania, Tianshi David Wu

Faculty, Staff and Students Publications

Background: Diabetes and insulin resistance are associated with higher risk of asthma exacerbation and preserved ratio impaired spirometry (PRISm), but the pathophysiology is unclear. These conditions may cause small airways dysfunction (SAD), which is an under-recognized cause of PRISm.

Objective: To determine whether insulin resistance and poor glucose control associate with SAD and to explore whether proteins prognostic of diabetes end-organ complications predict lung function abnormalities.

Methods: We recruited a prospective cohort of adults with physician-diagnosed asthma. Fasting insulin, glucose, hemoglobin A1c, and concentrations of 13 proteins prognostic of diabetes end-organ complications were measured. Static insulin resistance was calculated by …

Impact Of Iron-Bearing Fillers On The Mechanical Strength And Chemical Stability Of Magnesium Potassium Phosphate Matrices Incorporating Rhenium, Sergey Sayenko, Volodymyr Shkuropatenko, Hans Conrad Zur Loye, Petr Vecernik, Monika Kiselova, Vlastislav Kašpar, Vlastimil Miller, Petr Bezdicka, Jan Šubrt, Petra Ecorchard, Natalija Murafa, Iva Milisavljevic, Scott T. Misture

Faculty Publications

We report on the study of the immobilization process of non-radioactive rhenium (Re), a chemical analogue of technetium-99 (⁹⁹Tc), in compounds based on magnesium potassium phosphate (MKP), as well as the possibility of enhancing their properties with iron-bearing additives/fillers. Powdered Re2O7 was used as the initial Re-containing source. Because of the solubility and high leachability of Tc (VII), which is also volatile at high temperatures, its immobilization for long-term storage and disposal poses a serious challenge to researchers. Taking this into account, low-temperature stabilization technology based on MKP, a cementitious material, is currently considered promising. We prepared experimental …

Numerical Investigation Of A Dual-Mode Shape Memory Alloy Stent Enabling Secondary Expansion Via Focused Ultrasound: A Potential Strategy For Correcting In-Stent Restenosis, Stephen Asare, Lucinda Duncan, Josiah Owusu-Danquah, Brian L. Davis

Civil and Environmental Engineering Faculty Publications

Coronary stent implantation is an invasive procedure performed to correct atherosclerosis. The aftermath of this procedure is identified with neointimal hyperplasia, which contributes to in-stent restenosis (ISR), and thus remains a significant clinical challenge. This study introduces a novel, noninvasive conceptual approach for addressing ISR through the thermal activation of shape memory alloy (SMA) stent using focused ultrasound (FU) in a controlled manner to restore luminal patency. COMSOL Multiphysics and ABAQUS finite element software were employed to perform the numerical modeling to simulate the thermal and mechanical responses of the SMA stent integrated into the arterial wall. After 15 s …

The Effects Of A Viniyoga-Based Practice On Mental Health Clinicians' Perceived Stress, Burnout, And Quality Of Life, Julie Pate

Dissertations

Psychotherapists often experience stress when treating distressed or emotionally troubled patients due to the emotionally taxing nature of their work, which can lead to burnout and other negative consequences (Bell et al., 2023; Maslach & Leiter, 2016; Simionato & Simpson, 2018) Therapists find it challenging to maintain regular self-care routines (Driscoll, 2023; Baker & Gabriel, 2021; Posluns & Gall, 2020). With the constant demand for counselors (Bureau of Labor Statistics, U.S. Department of Labor, 2024), there is a critical need for effective stress management strategies to mitigate burnout risks (Substance Abuse and Mental Health Services Administration [SAMHSA], 2022; Sibitz, Pils, …

Meeting Nurses Where We're At, Michal Brown, Kayley Mclaughlin, Lauren Damm

Nurse Residency

PICOT Question: For night shift nurses, how does implementing flexible shift-friendly educational strategies, such as reordered or alternatively scheduled sessions, compare with traditional morning in person education classes affect their ability to positively participate and engage in required education throughout the nurse residency program?