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Articles 36631 - 36660 of 1826823
Full-Text Articles in Entire DC Network
February 12, 2026, James Madison University
February 12, 2026, James Madison University
The Breeze, 2020-
The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.
Charge Acceleration Without Radiation, Yakir Aharonov, D. Collins, S. Popescu
Charge Acceleration Without Radiation, Yakir Aharonov, D. Collins, S. Popescu
Mathematics, Physics, and Computer Science Faculty Articles and Research
The existence of electromagnetic radiation—radio waves, microwaves, light, X-rays, and so on—is one of the most important physical phenomena, and our ability to manipulate them is one of the most significant technological achievement of humankind. Underlying this ability is our understanding of how radiation is produced: Whenever an electric charge is accelerated, it radiates. Or, at least, this is how it has been hitherto universally thought. Here, we prove that quantum mechanically electric charges can be accelerated without radiating. The physical setup leading to this behavior is relatively simple (once one knows what to do), but its reasons are deep: …
Tumor-Immune-Neural Circuit Disrupts Energy Homeostasis In Cancer Cachexia, Xiuhui Shi, Alex X Arreola, Zhijun Zhou, Jingxuan Yang, Mingyang Liu, Yu Ren, Qun Chen, Xinjie Chen, Xinyu Yang, Yimei Meng, Jingyi Wang, Wenyi Luo, Michael C Rudolph, Rohan Varshney, Kar-Ming Fung, Chao Xu, Wei R Chen, Michael S Bronze, Lei Zheng, Yi-Ping Li, Courtney W Houchen, Yuqing Zhang, Min Li
Tumor-Immune-Neural Circuit Disrupts Energy Homeostasis In Cancer Cachexia, Xiuhui Shi, Alex X Arreola, Zhijun Zhou, Jingxuan Yang, Mingyang Liu, Yu Ren, Qun Chen, Xinjie Chen, Xinyu Yang, Yimei Meng, Jingyi Wang, Wenyi Luo, Michael C Rudolph, Rohan Varshney, Kar-Ming Fung, Chao Xu, Wei R Chen, Michael S Bronze, Lei Zheng, Yi-Ping Li, Courtney W Houchen, Yuqing Zhang, Min Li
Faculty, Staff and Student Publications
Cancer-induced cachexia and anorexia are debilitating complications across many cancers, yet effective treatments remain limited due to a poor understanding of the underlying mechanisms. Here, we identify an uncharacterized tumor-immune-neural circuit driving these syndromes, centered on growth and differentiation factor 15 (GDF15). Using genetically engineered mouse models, we find that loss of GDF15 protects against appetite loss, muscle wasting, and fat loss in pancreatic, lung, and skin cancers. Single-cell RNA sequencing reveals macrophages as a major source of GDF15, induced by tumor-derived colony-stimulating factor 1 (CSF1). GDF15 acts via the central nervous system to enhance β-adrenergic signaling in the tumor …
Solar Backscatter Ultraviolet (Buv) Retrievals Of Mid-Stratospheric Aerosols From The 2022 Hunga Eruption, Robert J.D. Spurr, Matt Christi, Nickolay A. Krotkov, Won Ei Choi, Simon Carn, Can Li, Et Al.
Solar Backscatter Ultraviolet (Buv) Retrievals Of Mid-Stratospheric Aerosols From The 2022 Hunga Eruption, Robert J.D. Spurr, Matt Christi, Nickolay A. Krotkov, Won Ei Choi, Simon Carn, Can Li, Et Al.
Michigan Tech Publications
On 15 January 2022, a highly explosive eruption of the submarine Hunga volcano (Kingdom of Tonga) generated the largest stratospheric hydration event ever observed and the largest aerosol perturbation since the 1991 Pinatubo eruption. Here, we develop a novel method for satellite retrieval of stratospheric aerosol optical depth (AOD) and layer peak height (zp) using solar backscattered ultraviolet (BUV) radiation; this is made possible by the exceptional mid-stratospheric altitude of the Hunga aerosols. We analyze BUV observations of the Hunga stratospheric aerosol cloud on 17 January 2022 (47 h after the eruption), using BUV band 1 measurements from the TROPOspheric …
Menopause 101, Stephanie Carlson, Emma Parkhurst, Ashley Yaugher, Cris Meier
Menopause 101, Stephanie Carlson, Emma Parkhurst, Ashley Yaugher, Cris Meier
All Current Publications
This fact sheet provides women with basic information about perimenopause, menopause, and postmenopause, along with helpful tips and resources to better prepare for or manage these phases of life.
Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte
Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte
Faculty Publications
Therapeutic proteins face a critical pharmacokinetic challenge: rapid clearance from circulation limits their clinical efficacy. Albumin-binding domains (ABDs) offer an elegant solution by enabling therapeutic proteins to “hitchhike” on serum albumin’s favorable 19-day half-life through FcRn-mediated recycling. Clinical validation through approved therapeutics like ozoralizumab demonstrates the success of this approach, with preclinical studies showing fusion to an ABD extended half-life to 18 days. This review provides an analysis of ABD-fusion protein design, integrating structural biology, computational prediction, and rational engineering principles. We catalog the major classes of albumin-binding modalities, including bacterial three-helix bundle domains, engineered peptides, antibody-derived binders, and alternative …
Colonisation, Globalisation And A Pandemic: Developing Understandings Of Inclusive Education In Malaysia, Vicky Bamsey, Yee Ling Lee, Moses Samuel
Colonisation, Globalisation And A Pandemic: Developing Understandings Of Inclusive Education In Malaysia, Vicky Bamsey, Yee Ling Lee, Moses Samuel
School of Law, Humanities and Social Sciences
This is a theoretical paper that examines how colonisation, globalisation and a crisis such as the Covid-19 pandemic have had a significant influence on the development of inclusive education policy and practice in Malaysia. Drawing on the ideas of dependency from Farid Alatas, and Carol Bacchi’s focus on the identification of the underlying problem within policies, as well as Stephen Ball’s policy cycle, we highlight how global events have repercussions at a policy level now and into the future. This paper contributes to the wider inclusive education debate through the innovative use of these three different theoretical lenses, informed by …
Teaching Peace, Stopping Bullying: The Transformative Power Of Kh Ahmad Dahlan’S Psychoeducation, Wahyu Nanda Eka Saputra, Anya Ahda Mahira, Salsa Puspita Dwi Djajuli
Teaching Peace, Stopping Bullying: The Transformative Power Of Kh Ahmad Dahlan’S Psychoeducation, Wahyu Nanda Eka Saputra, Anya Ahda Mahira, Salsa Puspita Dwi Djajuli
Buletin Konseling Inovatif
Bullying in schools remains a serious problem that negatively impacts students' academic and psychological development. A safe and violence-free learning environment is crucial to supporting the achievement of national education goals, thus requiring effective interventions to reduce bullying behavior. This study aims to test the effectiveness of group counseling services using psychoeducational techniques based on the teachings of KH. Ahmad Dahlan in reducing bullying behavior. The scope of the study focuses on the application of peaceful values in junior high schools as a prevention strategy and as a positive character development strategy for students. This study used a quantitative approach …
Tell Me Again Who Are You?, Heather Sellers
Tell Me Again Who Are You?, Heather Sellers
Creative Nonfiction Magazine
No abstract provided.
What Is The Future Of Diagnostic Medicine?, Michael Rosenwald
What Is The Future Of Diagnostic Medicine?, Michael Rosenwald
Creative Nonfiction Magazine
No abstract provided.
North Pole, South Pole, The Sea Of Carcinoma, Dev Hathaway
North Pole, South Pole, The Sea Of Carcinoma, Dev Hathaway
Creative Nonfiction Magazine
No abstract provided.
Trapeze Lessons, Marie Carter
Notes On Frey, Daniel Nester
The Truth About Cops And Dogs, Rebecca Skloot
The Truth About Cops And Dogs, Rebecca Skloot
Creative Nonfiction Magazine
No abstract provided.
The Pain Scale, Eula Biss
Badlands: Portrait Of A Competitive Eater, John O'Connor
Badlands: Portrait Of A Competitive Eater, John O'Connor
Creative Nonfiction Magazine
No abstract provided.
The Library As Storyplace, Rebecca T. Miller
The Library As Storyplace, Rebecca T. Miller
Creative Nonfiction Magazine
No abstract provided.
Mama, Che Cosa Vuoi Che Faccio?, James Vescovi
Mama, Che Cosa Vuoi Che Faccio?, James Vescovi
Creative Nonfiction Magazine
No abstract provided.
Daughters Of Monggrassano, Jeanna Lucci Canapari
Daughters Of Monggrassano, Jeanna Lucci Canapari
Creative Nonfiction Magazine
No abstract provided.
The Walls Of Gela, Edvige Giunta
Notes On Frey, Daniel Nester
Mountaineer, Craig Bernier
Then You'll Be Straight, Margaret Price
Then You'll Be Straight, Margaret Price
Creative Nonfiction Magazine
No abstract provided.
Ghost Children, D. Winston Brown
Fourteen Years In The Making, Megan Foss
Fourteen Years In The Making, Megan Foss
Creative Nonfiction Magazine
No abstract provided.
From "A Writer's Life", Gay Talese
A Pilot Study Evaluating Child Resistant Closures In Pharmaceuticals In The Developing Nation Of Ghana: Informing Global Paediatric Safety And Usability Standards, Samuel Ofosu, Kojo Agyapong Afrifah, Laura Bix
A Pilot Study Evaluating Child Resistant Closures In Pharmaceuticals In The Developing Nation Of Ghana: Informing Global Paediatric Safety And Usability Standards, Samuel Ofosu, Kojo Agyapong Afrifah, Laura Bix
Journal of Applied Packaging Research
Despite their proven effectiveness in preventing unintentional paediatric medication poisoning in high-income countries, the performance and usability of Child Resistant Closures (CRCs) remain underexplored in low and middle-income countries (LMICs).
To provide pilot data regarding the potential efficacy of using CRCs in LMICs, we conducted a study of the approach in a low-resourced region (Ghana, West Africa) by adapting testing protocols utilized in the United States (16 CFR Part 1700.20). The study utilized a convenience sample of children (n=50; 42-51 months) and adults (n=50; 50-70 years) to develop preliminary data related to the efficacy of a single design of CRC …