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Extracellular Matrix (Ecm) And Fibrosis In Adipose Tissue: Overview And Perspectives, Kai Sun, Xin Li, Philipp E Scherer Jan 2023

Extracellular Matrix (Ecm) And Fibrosis In Adipose Tissue: Overview And Perspectives, Kai Sun, Xin Li, Philipp E Scherer

Faculty, Staff and Student Publications

Fibrosis in adipose tissue is a major driver of obesity-related metabolic dysregulation. It is characterized by an overaccumulation of extracellular matrix (ECM) during unhealthy expansion of adipose tissue in response to over nutrition. In obese adipose-depots, hypoxia stimulates multiple pro-fibrotic signaling pathways in different cell populations, thereby inducing the overproduction of the ECM components, including collagens, noncollagenous proteins, and additional enzymatic components of ECM synthesis. As a consequence, local fibrosis develops. The result of fibrosis-induced mechanical stress not only triggers cell necrosis and inflammation locally in adipose tissue but also leads to system-wide lipotoxicity and insulin resistance. A better understanding …


Auditing Standards Board (Asb), Meeting Agenda, January 30-31, 2023, Virtual (Times Are Est), American Institute Of Certified Public Accountants. Auditing Standards Board Jan 2023

Auditing Standards Board (Asb), Meeting Agenda, January 30-31, 2023, Virtual (Times Are Est), American Institute Of Certified Public Accountants. Auditing Standards Board

Association Sections, Divisions, Boards, Teams

No abstract provided.


Homeschool Educators’ Perspectives About Student Needs Within Occupational Therapy Scope Of Practice: A Pilot Study, Susan L. Iliff, Mary T. Hill, Rose White, Aubrey Alexander Jan 2023

Homeschool Educators’ Perspectives About Student Needs Within Occupational Therapy Scope Of Practice: A Pilot Study, Susan L. Iliff, Mary T. Hill, Rose White, Aubrey Alexander

Pediatrics Research and Scholarship

Homeschool educators (n = 31) were recruited to complete an electronic survey describing their perspectives. Findings indicated that many students had medical/academic needs, and accessed additional services such as occupational therapy (OT). Data analysis of open-ended questions revealed common categories: (a) curricula met or did not meet student needs (b) participants had experience-based, general or no knowledge of OT and (c) most felt homeschooling was a positive experience and expressed that limited resources were available. Further research is warranted to investigate available resources, specific needs, and how to best support students who homeschool.


A Non-Reference Evaluation Of Underwater Image Enhancement Methods Using A New Underwater Image Dataset, Ashraf Saleem, Sidike Paheding, Nathir Rawashdeh, Ali Awad, Navjot Kaur Jan 2023

A Non-Reference Evaluation Of Underwater Image Enhancement Methods Using A New Underwater Image Dataset, Ashraf Saleem, Sidike Paheding, Nathir Rawashdeh, Ali Awad, Navjot Kaur

Michigan Tech Publications, Part 1

The rise of vision-based environmental, marine, and oceanic exploration research highlights the need for supporting underwater image enhancement techniques to help mitigate water effects on images such as blurriness, low color contrast, and poor quality. This paper presents an evaluation of common underwater image enhancement techniques using a new underwater image dataset. The collected dataset is comprised of 100 images of aquatic plants taken at a shallow depth of up to three meters from three different locations in the Great Lake Superior, USA, via a Remotely Operated Vehicle (ROV) equipped with a high-definition RGB camera. In particular, we use our …


Biogeochemical And Historical Drivers Of Microbial Community Composition And Structure In Sediments From Mercer Subglacial Lake, West Antarctica, Christina Davis, Ryan A. Venturelli, Alexander B. Michaud, Jon R. Hawkings, Amanda M. Achberger, Trista J. Vick-Majors, Et Al. Jan 2023

Biogeochemical And Historical Drivers Of Microbial Community Composition And Structure In Sediments From Mercer Subglacial Lake, West Antarctica, Christina Davis, Ryan A. Venturelli, Alexander B. Michaud, Jon R. Hawkings, Amanda M. Achberger, Trista J. Vick-Majors, Et Al.

Michigan Tech Publications, Part 1

Ice streams that flow into Ross Ice Shelf are underlain by water-saturated sediments, a dynamic hydrological system, and subglacial lakes that intermittently discharge water downstream across grounding zones of West Antarctic Ice Sheet (WAIS). A 2.06 m composite sediment profile was recently recovered from Mercer Subglacial Lake, a 15 m deep water cavity beneath a 1087 m thick portion of the Mercer Ice Stream. We examined microbial abundances, used 16S rRNA gene amplicon sequencing to assess community structures, and characterized extracellular polymeric substances (EPS) associated with distinct lithologic units in the sediments. Bacterial and archaeal communities in the surficial sediments …


Exploration Of The Nuclear Proteomes In The Ciliate Oxytricha Trifallax, Michael W Lu, Leslie Y Beh, V Talya Yerlici, Wenwen Fang, Katarzyna Kulej, Benjamin A Garcia, Laura F Landweber Jan 2023

Exploration Of The Nuclear Proteomes In The Ciliate Oxytricha Trifallax, Michael W Lu, Leslie Y Beh, V Talya Yerlici, Wenwen Fang, Katarzyna Kulej, Benjamin A Garcia, Laura F Landweber

2020-Current year OA Pubs

Nuclear dimorphism is a fundamental feature of ciliated protozoa, which have separate somatic and germline genomes in two distinct organelles within a single cell. The transcriptionally active somatic genome, contained within the physically larger macronucleus, is both structurally and functionally different from the silent germline genome housed in the smaller micronucleus. This difference in genome architecture is particularly exaggerated in


Amazon Web Services, The Lacanian Unconscious, And Digital Life, Marshall N. Armintor Jan 2023

Amazon Web Services, The Lacanian Unconscious, And Digital Life, Marshall N. Armintor

CLCWeb: Comparative Literature and Culture

In late 2011, ex-Amazon developer Steve Yegge’s rant about his former company described Amazon’s rapid transformation from an online bookstore to a web-services entity with a ruthlessly unified platform, all guided by the idea that the company’s effort to streamline its internal efficiency could be monetized, and the resultant software products sold through Amazon Web Services. The media consumerism that fed Amazon’s early years funded a surveilling behemoth, one that everyone feared Microsoft would become. As such, AWS has become a manifestation of the internet’s Lacanian unconscious (even providing the services and hosting for Reddit), structured around the optimization of …


Community Despite Connection: Resisting The Digital Logics Of Optimization And Failure, Irina Kalinka Jan 2023

Community Despite Connection: Resisting The Digital Logics Of Optimization And Failure, Irina Kalinka

CLCWeb: Comparative Literature and Culture

If a certain brand of aspirational tech-utopian discourse is to be believed, those privileged enough to be plugged into digital information technology are living through a golden age of connection. Platforms claim to facilitate sharing and partaking, bring people together, and bestow upon them new and improved spaces to gather and build communities. While reality differs decidedly from such idealized conceptions, it is nonetheless crucial to ask what kind of guiding vision is being instituted through such representational efforts: namely, the figure of community made operational and optimizable. This project will reject such idealized visions of coherent communities drawn together …


The Social Sinthome, Ryan Engley Jan 2023

The Social Sinthome, Ryan Engley

CLCWeb: Comparative Literature and Culture

Much of the critical discourse on social media misidentifies its problematic features as bugs, or problems to solve. Supposed solutions to these problems tend to focus on individual actions. We should delete the apps, own our own data, never click on recommended videos, and realize that we are the product. But if predatory algorithms succeed by individuating people—selling people “choice” and “options” as it harvests user data—then an entire online ecosystem arranged through the logic of that design can neither be meaningfully challenged nor effectively understood at the level of the individual alone. Transformative action addressing social media can only …


#Emotional: Exploitation & Burnout In Creator Culture, Sarah Thorne Jan 2023

#Emotional: Exploitation & Burnout In Creator Culture, Sarah Thorne

CLCWeb: Comparative Literature and Culture

In recent years, a growing list of content creators have published videos announcing that they are leaving YouTube, taking a break, or reducing their upload schedule (Alexander). Many of these young creators state that their decision resulted from burnout, caused by a relentless schedule and obsession with YouTube’s algorithm and analytics— tools essential to success on this highly competitive creative platform (Srnicek). Its opaque algorithm, however, induces anxiety; an affect described as that which “arises when the subject is confronted by the desire of the Other and does not know what object he is for that desire” (Evans 12). Here, …


“There Is No Pandemic”: On Memes, Algorithms And Other Interpassive Forms Of Right-Wing Disbelief, Scott Krzych Jan 2023

“There Is No Pandemic”: On Memes, Algorithms And Other Interpassive Forms Of Right-Wing Disbelief, Scott Krzych

CLCWeb: Comparative Literature and Culture

This essay examines several prominent memes that have circulated on Right-wing social media during the Covid-19 pandemic. The memes coordinate what I describe as a mode of interpassive humor, which positions those who “believe” in the crisis as naïve dupes, infantilizing those subjects who have fallen prey to the idea that they should take the pandemic seriously, and thereby delegating fearfulness to the other so that reactionary Covid-19 denialists may continue with their lives unaffected. The essay thereby seeks to draw suggestive lines of affiliation between studies of digital memes, evolutionary mimetics, and psychoanalytic theory, pointing to the algorithmic …


“Love Thy Social Media!”: Hysteria And The Interpassive Subject, Jack Black Jan 2023

“Love Thy Social Media!”: Hysteria And The Interpassive Subject, Jack Black

CLCWeb: Comparative Literature and Culture

According to the 2020 docudrama, The Social Dilemma, our very addiction to “social media” has, today, become encapsulated in the tensions between its facilitation as a mode of interpersonal communication and as an insidious conduit for machine learning, surveillance capitalism and manipulation. Amidst a variety of interviewees – many of whom are former employees of social media companies – the documentary finishes on a unanimous conclusion: something must change. By using the docudrama as a pertinent example of our “social media malaise,” and while remaining aware of the problems and unethical practices encompassing international digital/social media companies, this paper …


Stalking Oneself: The Fantasmatic Intersubjectivity Of Google, Alois Sieben Jan 2023

Stalking Oneself: The Fantasmatic Intersubjectivity Of Google, Alois Sieben

CLCWeb: Comparative Literature and Culture

This essay reads fictional and non-fictional accounts of digital stalking as signals of larger changes in intersubjectivity itself caused by Google. Most social media platforms trap users in imaginary relations, in which the other is encountered as a complete profile, but Google allows the searcher to locate an absence in the other in the form of a missing search result. As will be shown in an analysis of two contemporary novels whose first-person narrations center around Google-stalking, Caroline Kepnes’s You (2014) and Olivia Sudjic’s Sympathy (2017), Google’s mode of intersubjectivity amounts to an endless tunnel with no light at its …


Practicum & Internship Coordinators’ Experiences Amid Covid-19 Emergency Remote Teaching, Alexander T. Becnel, Sarah Irvin, Theodore Remley Jan 2023

Practicum & Internship Coordinators’ Experiences Amid Covid-19 Emergency Remote Teaching, Alexander T. Becnel, Sarah Irvin, Theodore Remley

Teaching and Supervision in Counseling

Although recent literature addresses online pedagogy and online counselor education, few articles address the challenges faced by counselor educators during emergency remote teaching, an unplanned and unanticipated switch from in-person education to online education. To address this gap, we conducted a phenomenological study of the lived experiences of practicum and internship coordinators (N = 8) during the emergency remote teaching phase of the COVID-19 pandemic. Five themes emerged: (a) uncertainty, (b) adaptation to leadership, (c) changes to student experience, (d) personal support, and (e) readiness. Implications for counselor educators and supervisors are addressed.


Basic Needs Adversities Among Counselors In Training: A Cluster Analysis, Jamie E. Crockett, Nathaniel N. Ivers Jan 2023

Basic Needs Adversities Among Counselors In Training: A Cluster Analysis, Jamie E. Crockett, Nathaniel N. Ivers

Teaching and Supervision in Counseling

During the intersection of COVID-19 with ongoing identity-based injustices in the US, Counselors-in-Training (CITs) experience unprecedented challenges including new or exacerbated basic needs insecurity. In this descriptive study, the authors examined Basic Needs Adversities (BNA) in a national sample of CITs (n = 233) during the first year of the COVID-19 pandemic. The authors used cluster analysis to investigate CITs reported BNAs and identified four subgroups of participants based on similarities and dissimilarities in the number and type of BNAs endorsed. The authors discuss implications for training and supervision with a focus on social justice in counselor education.


The Impact Of Supervisor Servant Leadership On Counselor Supervisee Burnout And Secondary Traumatic Stress, Colleen M. Grunhaus, Thomas J. Ward, Victor E. Tuazon, Kristal James Jan 2023

The Impact Of Supervisor Servant Leadership On Counselor Supervisee Burnout And Secondary Traumatic Stress, Colleen M. Grunhaus, Thomas J. Ward, Victor E. Tuazon, Kristal James

Teaching and Supervision in Counseling

This study investigates the prediction of supervisee burnout and secondary traumatic stress by perceived supervisor servant leadership. Authors hypothesized that the servant leadership of supervisors would predict diminished burnout and secondary traumatic stress of supervisees. A sample of 241 counseling supervisees participated in the cross-sectional study and completed instruments measuring burnout, secondary traumatic stress, and perceived servant leadership of their direct supervisors. Data were analyzed with two simple linear regressions, and a one-way MANOVA was performed to determine if supervisee burnout, supervisee secondary traumatic stress, and perceived servant leadership of supervisors differed significantly according to supervisor type (i.e., clinical, administrative, …


The Degree Of Knowledge Of Teaching Practices Based On Brain-Based Learning Among Faculty Members In The Faculty Of Education At Damascus University. درج ة المعرفة بالممارسات التدريسية القائمة على التعلم المستند إلى الدماغ لدى أعضاء الهيئة التعليمية في كلية التربية بجامعة دمشق, Zeinab Zeioud, Ameen Sheikh Mohammed Jan 2023

The Degree Of Knowledge Of Teaching Practices Based On Brain-Based Learning Among Faculty Members In The Faculty Of Education At Damascus University. درج ة المعرفة بالممارسات التدريسية القائمة على التعلم المستند إلى الدماغ لدى أعضاء الهيئة التعليمية في كلية التربية بجامعة دمشق, Zeinab Zeioud, Ameen Sheikh Mohammed

Association of Arab Universities Journal for Education and Psychology

The research aimed to identify the degree of knowledge of Faculty members in the faculty of Education at Damascus University about teaching practices based on brain-based learning using the descriptive analytical approach, that applied to a sample of Faculty members in the Faculty of Education at Damascus University. The research population consisted of (195) members in the Faculty of Education at Damascus University. The sample consisted of (60) faculty members chosen by the stratified random method from the departments of the Faculty of Education. The research instrument was a cognition test to measure the degree of knowledge of teaching practices …


An Analytical Study Of The Islamic Education Book For The Third Intermediate Grade In The Light Of Soft Skills. دراسة تحليلة لكتاب التربية الإسلامية للصف الثالث المتوسط في ضوء المهارات الناعمة, إبراهيم احمد الشرع, Norah Ibrahim Alanazi Jan 2023

An Analytical Study Of The Islamic Education Book For The Third Intermediate Grade In The Light Of Soft Skills. دراسة تحليلة لكتاب التربية الإسلامية للصف الثالث المتوسط في ضوء المهارات الناعمة, إبراهيم احمد الشرع, Norah Ibrahim Alanazi

Association of Arab Universities Journal for Education and Psychology

This study aimed to know the degree of inclusion of soft skills in the Islamic education book for the third intermediate graders in Saudi Arabia. A descriptive analytical approach was used. The results of the study showed that the skills of “problem solving and decision-making” and “critical and creative thinking” ranked first, and “cooperation and teamwork” skills ranked last in the book. The domain of "problem solving and decision-making" ranked first in the first part, while the domain of "critical and creative thinking" came first in the second part. In light of the results, the researchers recommend the need to …


Effects Of Telehealth On Dropout And Retention In Care Among Treatment-Seeking Individuals With Substance Use Disorder: A Retrospective Cohort Study, Danielle Gainer, Celeste Wong, Jared A. Embree, Nina Sardesh, Amna Amin, Natalie Lester Jan 2023

Effects Of Telehealth On Dropout And Retention In Care Among Treatment-Seeking Individuals With Substance Use Disorder: A Retrospective Cohort Study, Danielle Gainer, Celeste Wong, Jared A. Embree, Nina Sardesh, Amna Amin, Natalie Lester

Psychiatry Faculty Publications

Background: During the COVID-19 pandemic, telehealth became a widely used method of delivering treatment for substance use disorders (SUD), but its impact upon treatment engagement and dropout remains unknown. Methods: We conducted a retrospective analysis of adult SUD patients (n = 544) between October 2020 and June 2022 among a cohort of treatment-seeking patients at a nonprofit community behavioral health center in Southwestern Ohio. We estimated the likelihood of treatment dropout using survival curves and Cox proportional hazard models, comparing patients who used telehealth with video, telephone, or solely in-person services within the first 14 days of diagnosis. We also …


Artificial Intelligence As Clinician: An Argument For Ethical Use Of Future Technology In A Medical Setting, Sara Gaines Jan 2023

Artificial Intelligence As Clinician: An Argument For Ethical Use Of Future Technology In A Medical Setting, Sara Gaines

The International Journal of Ethical Leadership Special Volumes

No abstract provided.


Malum In Se: Starvation Crimes In International Law, Laura K. Graham Jan 2023

Malum In Se: Starvation Crimes In International Law, Laura K. Graham

The International Journal of Ethical Leadership Special Volumes

No abstract provided.


The Virtuous (Human) Soldier: A Macintyrian Approach To Moral Education In The Us Army, Nathan Riehl Jan 2023

The Virtuous (Human) Soldier: A Macintyrian Approach To Moral Education In The Us Army, Nathan Riehl

The International Journal of Ethical Leadership Special Volumes

No abstract provided.


On Video Games And Freedom, Warren Sexson Jan 2023

On Video Games And Freedom, Warren Sexson

Minnesota Journal of Law, Science & Technology

No abstract provided.


Frequency Of Von Willebrand Disease And Its Types: Data From A Tertiary Care Hospital Of Karachi, Pakistan, Jyoti Mohan Lal, Anila Rashid, Natasha Ali Jan 2023

Frequency Of Von Willebrand Disease And Its Types: Data From A Tertiary Care Hospital Of Karachi, Pakistan, Jyoti Mohan Lal, Anila Rashid, Natasha Ali

Department of Pathology and Laboratory Medicine

Introduction: von Willebrand disease is the most common inherited bleeding disorder. It is classified into 3 main types, type I and III are quantitative defects whereas type II is qualitative defect which is further sub-classified in to II-A, II-B, II-M, II-N. The aim of the present study is to see frequency and types of von Willebrand disease in a tertiary care hospital of Karachi, Pakistan.
Materials and methods: This retrospective cross-sectional study was conducted in the section of Hematology and Transfusion Medicine, Department of Pathology and Laboratory Medicine, the Aga Khan University hospital, Karachi, from May 2020 to April 2021 …


Filling In The Gaps: A Multiple Imputation Approach To Estimating Aging Curves In Baseball, Quang Nguyen, Gregory J. Matthews Jan 2023

Filling In The Gaps: A Multiple Imputation Approach To Estimating Aging Curves In Baseball, Quang Nguyen, Gregory J. Matthews

Mathematics and Statistics: Faculty Publications and Other Works

In sports, an aging curve depicts the relationship between average performance and age in athletes' careers. This paper investigates the aging curves for offensive players in the Major League Baseball. We study this problem in a missing data context and account for different types of dropouts of baseball players during their careers. In particular, the performance metric associated with the missing seasons is imputed using a multiple imputation model for multilevel data, and the aging curves are constructed based on the imputed datasets. We first perform a simulation study to evaluate the effects of different dropout mechanisms on the estimation …


Effectiveness Of Telemedicine In Diabetes Management: A Retrospective Study In An Urban Medically Underserved Population Area (Umupa), Lisa Ariellah Ward, Gulzar H. Shah, Jeffery A. Jones, Linda Kimsey, Hani M. Samawi Jan 2023

Effectiveness Of Telemedicine In Diabetes Management: A Retrospective Study In An Urban Medically Underserved Population Area (Umupa), Lisa Ariellah Ward, Gulzar H. Shah, Jeffery A. Jones, Linda Kimsey, Hani M. Samawi

Health Policy & Community Health: Faculty Publications

This paper examines the efficacy of telemedicine (TM) technology compared to traditional face-to-face (F2F) visits as an alternative healthcare delivery service for managing diabetes in populations residing in urban medically underserved areas (UMUPAs). Retrospective electronic patient health records (ePHR) with type 2 diabetes mellitus (T2DM) were examined from 1 January 2019 to 30 June 2021. Multiple linear regression models indicated that T2DM patients with uncontrolled diabetes utilizing TM were similar to traditional visits in lowering hemoglobin (HbA1c) levels. The healthcare service type significantly predicted HbA1c % values, as the regression coefficient for TM (vs. F2F) showed a significant negative association …


The Known And Unknowns Of Aphid Biotypes, And Their Role In Mediating Host Plant Defenses, Neetu Khanal, Christopher Vitek, Rupesh R. Kariyat Jan 2023

The Known And Unknowns Of Aphid Biotypes, And Their Role In Mediating Host Plant Defenses, Neetu Khanal, Christopher Vitek, Rupesh R. Kariyat

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Insect species are subjected to disparate selection pressure due to various biotic and abiotic stresses. Management practices including the heavy use of chemical insecticides and introduction of insect-resistant plant cultivars have been found to accelerate these processes. Clearly, natural selection coupled with human intervention have led to insect adaptations that alter phenotypes and genetic structure over time, producing distinct individuals with specialized traits, within the populations, commonly defined as biotypes. Biotypes are commonly found to have better fitness in the new environment and, in the case of aphids, the most commonly studied system for biotypes, have the ability to successfully …


Building Foundations For Friendship: Preventing Bullying Behavior In Preschool, Kara M. Mcgoey, Allison Aberson, Bridget Green, Seana Bandi Stewart Jan 2023

Building Foundations For Friendship: Preventing Bullying Behavior In Preschool, Kara M. Mcgoey, Allison Aberson, Bridget Green, Seana Bandi Stewart

Perspectives on Early Childhood Psychology and Education

Early childhood is an essential time for social-emotional learning and the development of appropriate peer interactions. Preschool children also begin to use more physical and verbal forms of aggression and bullying within their relationships with peers. The Building Foundations for Friendship (BFF) curriculum was designed to teach preschool-aged children appropriate social skills to prevent bullying. The topics discussed in this curriculum include developing friendship skills, identifying various peer interactions, and learning how to appropriately respond to a peer’s aggressive behavior. It was hypothesized that preschool students’ social skills and social behavior would improve after implementation of the BFF curriculum. The …


Strategies To Promote Positive Mealtime Behavior In Early Childhood, Hailey E. Ripple, Hallie M. Smith, Kayla Bates-Brantley Jan 2023

Strategies To Promote Positive Mealtime Behavior In Early Childhood, Hailey E. Ripple, Hallie M. Smith, Kayla Bates-Brantley

Perspectives on Early Childhood Psychology and Education

Picky eating and problem behavior during meals are commonly reported issues among young children, particularly toddlers (Manikam & Perman, 2000). It is estimated that up to 50% of children under the age of 5 experience difficulties during mealtimes (Benjasuwantep et al., 2013). These difficulties may include tantrums when nonpreferred foods are presented, turning their head away from bites, pushing food away, crying, spitting out bites of nonpreferred food, and holding bites in the mouth. Over time, these behaviors can lead to significant limitations in the variety and amount of foods that children consume, thus compromising their growth and development. While …


The Pod Generation, Dereck Daschke Jan 2023

The Pod Generation, Dereck Daschke

Journal of Religion & Film

This is a film review of The Pod Generation (2023), directed by Sophie Barthes.