Digital Commons Network^™

The Role Of The Neurodevelopmental Disorder Gene Myt1l In Mammalian Brain Development, Jiayang Chen

Arts & Sciences Graduate Student Theses and Dissertations

Recent human genetic studies have associated mutations in a gene called Myelin Transcription Factor 1 Like (MYT1L) with neurodevelopmental disorders (NDDs). Patients with MYT1L loss of function (LoF) mutations (MYT1L Syndrome patients) demonstrate shared symptoms such as microcephaly, attention deficit and hyperactivity disorder (ADHD), and obesity. Despite prior studies showing MYT1L overexpression facilitates neuronal differentiation in vitro, its functions in vivo, especially in the mammalian brain, and how its mutation leads to human disease pathology remains poorly understood. Here, I established the first mouse model of MYT1L Syndrome mimicking a patient specific LoF mutation. I found mice with Myt1l heterozygous …

2023 February 7, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, 2023 February 7

Call for Nominations – Spring 2022  Faculty Senate Senator Seats and FS Committees

2023 February 7, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, 2023 February 7

Call for Nominations – Spring 2022  Faculty Senate Senator Seats and FS Committees

Digitalcommons@Uno And Building Your Scholarly Profile, Jennie Tobler-Gaston

Criss Library Faculty Proceedings & Presentations

This workshop presented the details of what the University of Nebraska at Omaha's Institutional Repository, DigitalCommons@UNO, is and how to get work uploaded to the repository. It also covered how to build a scholarly profile using the PINPOINT (Portfolio, Institutional repository, Network, Publishing, Open access, ID, Name, and Tracking) method.

Meeting Minutes 2-7-23, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Ucc Agenda 2-7-23, Angela Brock

UCC Agendas/Minutes

No abstract provided.

A Proposed Meta-Reality Immersive Development Pipeline: Generative Ai Models And Extended Reality (Xr) Content For The Metaverse, Jay Ratican, James Hutson, Andrew Wright

Faculty Scholarship

The realization of an interoperable and scalable virtual platform, currently known as the “metaverse,” is inevitable, but many technological challenges need to be overcome first. With the metaverse still in a nascent phase, research currently indicates that building a new 3D social environment capable of interoperable avatars and digital transactions will represent most of the initial investment in time and capital. The return on investment, however, is worth the financial risk for firms like Meta, Google, and Apple. While the current virtual space of the metaverse is worth $6.30 billion, that is expected to grow to $84.09 billion by the …

A Critical Review On Water Overconsumption In Lignocellulosic Biomass Pretreatment For Ethanol Production Through Enzymic Hydrolysis And Fermentation, Jikai Zhao, Juhee Lee, Donghai Wang

School of Earth, Environmental, & Marine Sciences Faculty Publications

Global demand for renewable and sustainable energy fostered the considerable development of biomass-to-ethanol valorization strategies. Thermochemical pretreatment methods have been proposed to render biomass more amenable to enzymatic and microbial digestion. However, the efforts have not led to its industrial-scale worldwide realization. One of the obstacles to commercialization could be related to water overconsumption, as excessive water washing of the pretreated slurry is often performed to remove inhibitory compounds and residual chemicals after biomass pretreatment. Only increasing solid loading for biomass pretreatment results in ineffective pretreatment performance, more inhibitors formation, and high viscosity, which in turn necessitates the water washing …

Examining The Intentions To Seek Postgraduate Education (Professional Degree) Amongst University Students In China : The Moderating Role Of Chinese Social Network, Ao Liang

Lingnan Theses (Doctoral degree)

Background: In 2020, the Degree Committee of the State Council collaborated with the Ministry of Education in advocating the policy of ‘Postgraduate education of professional degree development plan (2020–2025), to continuously increase postgraduate education (professional degree) enrolment. Policy implementations by the Chinese government on the development of postgraduate educations how that many efforts and inputs have been made previously on the professional degree of the Chinese government (e.g., reducing the corresponding quota number of 5%–10% of academic degree and providing near 1.2 trillion RMB for the development of professional degrees).However, the results of expansion on professional postgraduate degrees have not …

Human Saliency-Driven Patch-Based Matching For Interpretable Post-Mortem Iris Recognition, Aidan Boyd, Daniel Moreira, Andrey Kuehlkamp, Kevin Bowyer, Adam Czajka

Computer Science: Faculty Publications and Other Works

Forensic iris recognition, as opposed to live iris recognition, is an emerging research area that leverages the discriminative power of iris biometrics to aid human examiners in their efforts to identify deceased persons. As a machine learning-based technique in a predominantly human-controlled task, forensic recognition serves as “back-up” to human expertise in the task of post-mortem identification. As such, the machine learning model must be (a) interpretable, and (b) post-mortem-specific, to account for changes in decaying eye tissue. In this work, we propose a method that satisfies both requirements, and that approaches the creation of a post-mortem-specific feature extractor in …

Peer-Led Team Learning Strategies In Engineering Pathways, Kimberly Luthi, Monica Surrency, John Keith Wilson, David Harvie

Publications

Train Peer-Leaders on difference between mentor/tutor and Peer Leader. Focuses on leadership skills. Provides technology resources tutorial. Provided suggested teaching and learning strategies for PLTL activities.

Integrating Virtual Reality Into The Asynchronous Learning Environment, Cheri Marcham, Dave D.C. Delcastillo, David Thirtyacre, Brian Sanders

Publications

• 4 presentations
• Covers a spectrum of subject matter
• Real to virtual and virtual to real
• Want to highlight
• What the goal was
• How it was integrated into effective learning experiences

Gender, Sexual Orientation, Ethnicity And Socioeconomic Factors Influence How Wildland Firefighters Communicate Their Work Experiences, Miranda Ragland, Jennifer Harrell, Molly Ripper, Seth Pearson, Rachel Granberg, Robin M. Verble

Biological Sciences Faculty Research & Creative Works

As Climates Change, Natural Resource Professionals Are Often Working on the Frontlines of Intensifying Environmental Disasters, Acting in Both Scientific and Emergency Response Roles. One Subset of This Group, Wildland Firefighters Often Engage in Multifaceted Careers that Incorporate Elements of Resource Planning, Conservation Management, Community Disaster Relief, and Operational Management. Despite These STEM Roles and Nearly Half (48%) of Them Having Earned at Least a bachelor's degree, usually in a STEM Field, Wildland Firefighters Are Almost Exclusively Lumped with Emergency Responders in the Scientific Literature. We Surveyed 708 Wildland Firefighters with 9 Open Response Questions as Part of a Larger …

Message From The President, Georgia Southern University

Messages from the President

Dear Colleagues

Solidarity And Strife After The Atlanta Spa Shootings: A Mixed Methods Study Characterizing Twitter Discussions By Qualitative Analysis And Machine Learning, Shaniece Criss, Thu T. Nguyen, Eli K. Michaels, Gilbert C. Gee, Mathew V. Kiang, Quynh C. Nguyen, Samantha Norton, Eli Titherington, Leah Nguyen, Isha Yardi, Melanie Kim, Nhung Thai, Ariel Shepherd, Chris J. Kennedy

Open Access Fund Publications

Background: On March 16, 2021, a white man shot and killed eight victims, six of whom were Asian women at Atlanta-area spa and massage parlors. The aims of the study were to: (1) qualitatively summarize themes of tweets related to race, ethnicity, and racism immediately following the Atlanta spa shootings, and (2) examine temporal trends in expressions hate speech and solidarity before and after the Atlanta spa shootings using a new methodology for hate speech analysis.

Methods: A random 1% sample of publicly available tweets was collected from January to April 2021. The analytic sample included 708,933 tweets using race-related …

Comparison Of Cycloplegia At 20- And 30-Minutes Following Proxymetacaine And Cyclopentolate Instillation In White 12-13-Year-Olds, Megan Doyle, Veronica O'Dwyer, Siofra Harrington

Articles

Clinical Relevance

Reducing the time between drop instillation and refraction reduces the time paediatric patients and young adults spend in practice, facilitating more eye examinations daily.

Background

The current procedure for paediatric cycloplegic refraction is to wait for at least 30-minutes post-instillation of a cycloplegic before measuring spherical equivalent refraction. This study compared cycloplegia at 20- and 30-minutes following 0.5% proxymetacaine and 1.0% cyclopentolate in 12-13-year-olds.

Methods

Participants were 99 white 12-13-year-olds. One drop of proxymetacaine hydrochloride (Minims, 0.5% w/v, Bausch & Lomb, UK) followed by one drop of cyclopentolate hydrochloride (Minims, 1.0% w/v, Bausch & Lomb, UK) was instilled …

Final 2021 Unreclaimed Sites Sampling Ur-36 Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Final 2021 Unreclaimed Sites Sampling Ur-05 Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Emerging Technologies For Indigenous Knowledge Management By Public Libraries Of Akwa Ibom State, Daniel Aloysius, Mercy Daniel Ebong Ph.D

Library Philosophy and Practice (e-journal)

This paper examines emerging technologies for indigenous knowledge management by public libraries of Akwa Ibom State. It conceptualise indigenous knowledge, indigenous knowledge management and emerging technologies. The different Indigenous knowledge of Akwa Ibom State were explored. The emerging technologies for management of indigenous knowledge were evaluated. The paper concluded that indigenous knowledge is the identity and prestige of the local people as their cultural heritage over centuries are embedded in it. Hence, it should be adequately managed by public libraries for posterity of the local people and indeed the world over. The paper recommends among others that government should adequately …

When Normal Is Not Normal: A Theory Of The Non-Linear And Discontinuous Process Of Desired Change And Its Managerial Implications, Richard Boyatzis, Udayan Dhar

Faculty Journal Articles

Desirable change may appear chaotic, slow, or not sustainable. We may expect linear, continuous change, but it eludes us. Measurement and statistical analysis about behavior change often requires data showing continuity and having normal (i.e., Gaussian) distributions. When we encounter phenomenon that does not fit this expectation, we seek to transform the data to render it compatible with our method of analysis. We move from actual behavior to perception of it through surveys or transformations of the data. We believe this ignores “naturally” occurring data and what it says. Such techniques are convenient for statistics but may hide important features …

A Comprehensive Framework For The Use Of Sugarcane Bagasse Ash As Cement And Sand Replacement In Concrete Materials, Sujata Subedi

LSU Doctoral Dissertations

Sugarcane bagasse ash (BA), an agricultural byproduct, has been suggested as a sustainable material to partially replace cement and sand in traditional concrete. However, the feasibility of using BA in novel concrete materials, such as engineered cementitious composites (ECC) and fiber-reinforced geopolymer composites (FRGC), has not been investigated. Therefore, the objectives of this study are to: (a) characterize the properties of Louisiana BA produced from different methodologies; (b) quantify the influence of BA as supplementary cementitious material (SCM) on concrete properties; (c) assess the feasibility of developing normal- and high-strength ECCs using BA as SCM and fine aggregate, and (d) …

Fifty Years Of Global Cardiovascular Research In Africa: A Scientometric Analysis, 1971 To 2021, Jean Jacques Noubiap, Dominic Millenaar, Dike Ojji, Q Eileen Wafford, Christian Ukena, Michael Böhm, Karen Sliwa, Mark D Huffman, Felix Mahfoud

2020-Current year OA Pubs

Background To analyze the quantity and impact of cardiovascular research done in Africa or coauthored by researchers based in Africa, their determinants, and the patterns of research collaboration. Methods and Results We retrieved data from Web of Science and additional sources. We analyzed temporal trends from 1971 to 2021 and geographical distribution, research impact using country-level h-index, international research cooperation, and associations of research quantity and quality using linear regression. The annual volume of cardiovascular research from Africa has increased from 4 publications in 1971 to 3867 in 2020 and currently represents ~3% of the global cardiovascular research output. Authors …

Effects Of Neighborhood Disadvantage And Peer Deviance On Conduct Problems: Interactions With Age Of Onset, Courtney Marie Goetz

LSU Master's Theses

Youth with conduct problems (CP) generally fall into two developmental classifications, child-onset and adolescent-onset, which exhibit different causal processes and life course trajectories. Research suggests that child-onset CP is more likely to be related to individual predispositions, while adolescent-onset CP is more associated with social factors, such as peer delinquency. Living in impoverished and disorganized neighborhoods increases the risk for associating with deviant peers. Thus, the current study tested the hypothesis that neighborhood factors would be more strongly associated with adolescent-onset CP than child-onset CP, which would be explained by a greater association with deviant peers. Linear and negative binomial …

Glacial Lake Outburst Floods Threaten Millions Globally, Caroline Taylor, Tom R. Robinson, Stuart Dunning, Carr J Rachel, Matthew Westoby

School of Geography, Earth and Environmental Sciences

AbstractGlacial lake outburst floods (GLOFs) represent a major hazard and can result in significant loss of life. Globally, since 1990, the number and size of glacial lakes has grown rapidly along with downstream population, while socio-economic vulnerability has decreased. Nevertheless, contemporary exposure and vulnerability to GLOFs at the global scale has never been quantified. Here we show that 15 million people globally are exposed to impacts from potential GLOFs. Populations in High Mountains Asia (HMA) are the most exposed and on average live closest to glacial lakes with ~1 million people living within 10 km of a glacial lake. More …

Evaluation Of Apparent Diffusion Coefficient Repeatability And Reproducibility For Preclinical Mris Using Standardized Procedures And A Diffusion-Weighted Imaging Phantom, Dariya Malyarenko, Ghoncheh Amouzandeh, Stephen Pickup, Rong Zhou, Henry Charles Manning, Seth T Gammon, Kooresh I Shoghi, James D Quirk, Renuka Sriram, Peder Larson, Michael T Lewis, Robia G Pautler, Paul E Kinahan, Mark Muzi, Thomas L Chenevert

Faculty, Staff and Students Publications

Relevant to co-clinical trials, the goal of this work was to assess repeatability, reproducibility, and bias of the apparent diffusion coefficient (ADC) for preclinical MRIs using standardized procedures for comparison to performance of clinical MRIs. A temperature-controlled phantom provided an absolute reference standard to measure spatial uniformity of these performance metrics. Seven institutions participated in the study, wherein diffusion-weighted imaging (DWI) data were acquired over multiple days on 10 preclinical scanners, from 3 vendors, at 6 field strengths. Centralized versus site-based analysis was compared to illustrate incremental variance due to processing workflow. At magnet isocenter, short-term (intra-exam) and long-term (multiday) …

The Impacts Of A Changing Climate And Human Activities On The Hydrology In High Mountain Asia, Fadji Z. Maina

Sustainability Seminar Series

High Mountain Asia (HMA), the third pole, encompasses Asia’s most prominent rivers such as the Ganges, the Indus, and the Yangtze. HMA, home to over a billion people, experiences warming at a rate that is double the global average making it one of the most vulnerable water towers on Earth in addition to a significant decline in groundwater due to anthropogenic activities and high vegetation greening rates. Understanding the changes in water budgets in HMA and their drivers is essential for water management and climate change mitigation strategies. We used remotely sensed datasets to represent the hydrology of the region …

Putin’S Ukraine Invasion: Turbocharging Sino-Russian Collaboration In Energy, Maritime Security, And Beyond?, Andrew S. Erickson, Gabriel B. Collins

Naval War College Review

Putin’s war of choice in Ukraine will continue to send shock waves across the shores of maritime Asia for years, with unfolding impacts on ecosystems inhabited by oil barrels, gas pipelines, submarine technologies, jet engines, and basing access, within a context of a China-Russia relationship characterized over the centuries by cycles of fear, temporary bonds, and renewed division.

Nuclear Weapons In Russia’S War Against Ukraine, Stephen Blank

Naval War College Review

Western concern about Russian nuclear weapons’ potential deployment continues to suffuse policy responses to the Ukraine war, inhibiting relief efforts. Russia’s rhetoric and past exercises contribute to the pervasive Western belief that Russia might use nuclear weapons, including in a conflict that begins as a purely conventional war, to force its enemies to accept its terms.

Naval Considerations In The Russo-Ukrainian War, Seth Cropsey

Naval War College Review

Russia’s grand military strategy has a distinct maritime bent, the Ukrainian south coast is Russia’s most tangible strategic prize, and naval forces are crucial to holding it. Since the war’s beginning, Ukraine’s carefully planned strategy has applied stress to key elements of Russia’s maritime strategy, and Ukraine’s theory of victory is shaped by maritime considerations as thoroughly as Russia’s.

Autumn 2022 Full Issue, The U.S. Naval War College

Naval War College Review

No abstract provided.