Digital Commons Network^™

Spontaneous Retroperitoneal Hematoma In Vitamin C Deficiency, Indira Acharya, Ashik Pokharel, David S. Weisman

Journal of Community Hospital Internal Medicine Perspectives

Retroperitoneal hematoma is rare but potentially life-threatening. It is commonly caused by traumatic or iatrogenic vascular injury, retroperitoneal neoplasm, coagulopathy, chronic anticoagulation, or fibrinolytic therapy. However, retroperitoneal hematoma due to vitamin C deficiency is rare. Here, we report a case of 40 years old man who developed retroperitoneal hematoma in context of very low vitamin C. To our knowledge, this is the second described case of retroperitoneal hematoma from vitamin C deficiency.

A Case Of Candida Empyema In A Patient With Esophagopleural Fistula, Ramez Alyacoub

Journal of Community Hospital Internal Medicine Perspectives

Fungal empyema is a rare entity, particularly in immunocompetent patients. It has been noted to occur in a patient with esophageal perforation. Esophageal perforation has a wide range of clinical presentations and associated complications depending on the size and site of perforation. Although the classic presentation of esophageal perforation, also known as Boerhaave syndrome, is often dramatic with hemodynamic instability and mediastinitis. Smaller perforations and esophageopleural fistula can lead to more indolent presentation in the form of complications such as necrotizing pneumonia and pleural effusions. Here we present a 42-year-old patient with alcohol withdrawal and aspiration pneumonia, later found to …

Disseminated Cryptococcosis In An Immunocompromised Patient With Altered Mental Status And A Lung Nodule, Dena H. Tran, Avelino C. Verceles, Ellen T. Marciniak

Journal of Community Hospital Internal Medicine Perspectives

Introduction: Disseminated cryptococcosis is an opportunistic infection that commonly affects the central nervous and respiratory systems and is often fatal in immunocompromised patients. Diagnosing disseminated cryptococcosis is challenging at times due to the nonspecific presentation, resulting in delayed treatment and increased mortality. Case Presentation: A 48-year-old man presented with altered mental status and shortness of breath requiring intubation. Medical history was significant for rheumatoid arthritis, diabetes mellitus, chronic kidney disease, sarcoidosis, and polymyalgia rheumatica. Home medications included prednisone, methotrexate, and tocilizumab. Computed tomography chest revealed multifocal pneumonia with a cavitary nodule with halo sign. One week after extubation, the patient …

Rheumatoid Vasculitis Presenting With Incidental Renal Infarcts: Case Report And Literature Review, Fatima Halilu, Howard Hauptman

Journal of Community Hospital Internal Medicine Perspectives

Rheumatoid vasculitis is a rare and late complication of rheumatoid arthritis, affecting small to medium sized vessels. Inflammation in the vessel wall produces an occlusive vasculopathy with downstream infarction. We present the case of a 70-year-old female with long standing stable RA status post recent COVID-19 vaccination admitted with community acquired Legionnaires disease found to have an incidental renal infarct on chest imaging without a clear etiology. She improved from a respiratory standpoint but then had a fever spike with repeat imaging showing a second renal infarct and CT angiography showing extensive beading with aneurysmal dilation in the bilateral hepatic …

Case Report Of Acute Q Fever With Hepatitis Progressing To Chronic Q Fever With Endocarditis, Abbas B. Jama, Jessica L. Sheehy, Hassan Mohamed, Noura Attallah, Esraa Hassan, Anwar Khedr, Hisham Mushtaq, Omar Y. Mousa, James J. Milavetz, Ali Sadik, Mohamad El Labban, Nitesh Jain, Salim Surani, Eric O. Gomez Urena, Syed Anjum Khan

Journal of Community Hospital Internal Medicine Perspectives

A 35-year-old male greenhouse worker presented with myalgia, fatigue, and fever. Initially, he was thought to have an unspecified viral infection and was treated with conservative therapy. However, the patient’s symptoms persisted, and he reported additional symptoms of mild abdominal pain and headaches. Laboratory evaluation was significant for elevated liver enzymes. Due to concern for acute hepatitis and persistent fever the patient was hospitalized. During his hospital course, no infectious etiology was found to explain his symptoms. After discharge from the hospital, additional testing showed positive serology for Q fever IgG phase II antibody (1:8192) and phase II antibody IgM …

Simultaneous Determination Of 24 Congeners Of 2- And 3‑Monochloropropanediol Esters And 7 Congeners Of Glycidyl Esters Using Direct Multi-Residue Analytical Lc-Ms/Ms Methods In Various Food Matrices, Ching-Chang Lee, Bo-Lun Lin, Yi-Wen Huang, Ning-Syuan Hsu, Wei-Hsiang Chang

Journal of Food and Drug Analysis

Glycidyl esters (GEs) and 2- and 3-monochloropropanediol esters (MCPDEs) are emerging process-generated food contaminants known as possible carcinogens. Herein, a direct method is developed and validated for the first time to simultaneously quantify seven GEs and twenty-four MCPDE congeners of processed foods using liquid chromatography-tandem mass spectrometry in a single sequence without ester cleavage or derivatisation, thereby allowing for the simultaneous analysis of numerous food matrices with high accuracy and precision. Our results show levels of GEs varying from

Erinacine S From Hericium Erinaceus Mycelium Promotes Neuronal Regeneration By Inducing Neurosteroids Accumulation, Chun-Yu Lin, Yi-Ju Chen, Chih-Hsuan Hsu, Yu-Hsuan Lin, Peng-Tzu Chen, Ting-Han Kuo, Chris T. Ho, Hsin-Hua Chen, Sih-Jia Huang, Ho-Chieh Chiu, Chin-Chu Chen, Eric Hwang

Journal of Food and Drug Analysis

Erinacines derived from Hericium erinaceus have been shown to possess various health benefits including neuroprotective effect against neurodegenerative diseases, yet the underlying mechanism remains unknown. Here we found that erinacine S enhances neurite outgrowth in a cell autonomous fashion. It promotes post-injury axon regeneration of PNS neurons and enhances regeneration on inhibitory substrates of CNS neurons. Using RNA-seq and bioinformatic analyses, erinacine S was found to cause the accumulation of neurosteroids in neurons. ELISA and neurosteroidogenesis inhibitor assays were performed to validate this effect. This research uncovers a previously unknown effect of erinacine S on raising the level of neurosteroids.

Recent Developments In Detection And Therapeutic Approaches For Antibiotic-Resistant Bacterial Infections, Kavya Moorthy, Kai-Chih Chang, Hsueh-Hui Yang, Wen-Min Su, Cheng-Kang Chiang, Zhiqin Yuan

Journal of Food and Drug Analysis

Owing to the widespread emergence and proliferation of antibiotic-resistant bacteria, the therapeutic benefits of antibiotics have been reduced. In addition, the ongoing evolution of multidrug-resistant pathogens poses a challenge for the scientific community to develop sensitive analytical methods and innovative antimicrobial agents for the detection and treatment of drug-resistant bacterial infections. In this review, we have described the antibiotic resistance mechanisms that occur in bacteria and summarized the recent developments in detection strategies for monitoring drug resistance using different diagnostic methods in three aspects, including electrostatic attraction, chemical reaction, and probe-free analysis. Additionally, to understand the effective inhibition of drug-resistant …

Elderly Or Disabled Registered Sex Offenders: Are They Experiencing Cruel And Unusual Punishment Under Ohio Sex Offender Classification And Registration Laws?, Susana Tolentino

University of Cincinnati Law Review

No abstract provided.

Taking The American Dream – A Remedy For Home Equity Theft Following The Sixth Circuit's Ruling In Harrison V. Montgomery County, Ohio, Elizabeth Black

University of Cincinnati Law Review

No abstract provided.

A Vision Of The Anti-Racist Public Corporation, Steven A. Ramirez

University of Cincinnati Law Review

No abstract provided.

The Eleventh Amendment And Nondiverse Suits Against States, Collin Hong

University of Cincinnati Law Review

Since Hans v. Louisiana (1890), the Supreme Court has maintained that the Eleventh Amendment protects states from suits by plaintiffs who are citizens of other states and by citizens of that state, despite the text of the Eleventh Amendment specifying that only suits from citizens of other states are barred. Scholars have noted that what therefore protects the states from suits against their own citizens is not the Eleventh Amendment, but rather a common-law immunity that existed between nations at the founding. That immunity applied both to states and to foreign nations. This article argues that just as Congress has …

Markets As Legal Constructions, Gregory Brazeal

University of Cincinnati Law Review

Since at least the late 1970s, popular political and economic debates in the United States have often been framed in terms of a choice between “government” and “the market.” In addition, debates have often assumed that “the market” is associated with freedom while government “regulation” or “interference in the market” constitutes oppression.

This article begins by making the familiar observation that the distinction between “government” and “the market,” at least when taken at face value, makes no sense. Even idealized laissez-faire markets are creatures of the state and its market-structuring laws, including criminal law and the laws of property, contracts, …

Comparison Of Flex Vs. Residential Clinical Education Program Outcomes: Physical Therapy Students’ Self-Efficacy, Confidence, And Clinical Competence, Derrick F. Campbell, Jean-Michel Brismée, Brad S. Allen, Troy Hooper, Manuel A. Domenech, Kathleen Manella

Education Collection

Purpose: Alternative flexible (Flex) path Doctor of Physical Therapy (DPT) programs may have an emerging footprint. The differences between Flex and traditional residential DPT program clinical experience outcomes remain unknown. The purpose of this study was to evaluate Flex and residential DPT students’ clinical reasoning self-efficacy, confidence with treating, and Clinical Performance Instrument (CPI) clinical reasoning and summative scores during clinical experiences.

Methods: A descriptive and exploratory cross-sectional survey was used with a voluntary convenience sample of 211 university DPT students during Fall 2020 full-time clinical experiences. Descriptive and inferential statistics evaluated differences in Flex and residential DPT program …

Water Challenges In Socio-Ecological Systems: Is Human Decision-Making Accounted For In The Analysis Of Climate Change Adaptation Options?, Sara Zanini

Fondazione Eni Enrico Mattei Working Papers

This mixed-method systematic review is motivated by the willingness to identify the efforts of the most recent developments of the literature on the understanding of water challenges in socioecological systems, particularly coastal ones. The attention, in the exercise, is directed at the analysis of individual and collective decision-making processes concerning the use of the environmental good. This is because ultimately, if it is true that water resources are affected by external trends and shocks, it is also relevant how distinct paths of local and regional level responses impact on resource status. The inquiry, departs from a conceptual point of view …

Usa V. George Stoney

2023 Decisions

USDC for the Middle District of Pennsylvania

Comparison Of Flex Vs. Residential Clinical Education Program Outcomes: Physical Therapy Students’ Self-Efficacy, Confidence, And Clinical Competence, Derrick F. Campbell, Jean-Michel Brismee, Brad Allen, Troy L. Hooper, Manuel A. Domenech, Kathleen J. Manella

HPD Articles

Purpose: Alternative flexible (Flex) path Doctor of Physical Therapy (DPT) programs may have an emerging footprint. The differences between Flex and traditional residential DPT program clinical experience outcomes remain unknown. The purpose of this study was to evaluate Flex and residential DPT students’ clinical reasoning self-efficacy, confidence with treating, and Clinical Performance Instrument (CPI) clinical reasoning and summative scores during clinical experiences.

Methods: A descriptive and exploratory cross-sectional survey was used with a voluntary convenience sample of 211 university DPT students during Fall 2020 full-time clinical experiences. Descriptive and inferential statistics evaluated differences in Flex and residential DPT program students’ …

Spine Bracing: When To Utilize-A Narrative Review., John L Cerillo, Alexander N Becsey, Chai P Sanghadia, Kevin T Root, Brandon Lucke-Wold

HPD Articles

Spinal bracing is a common non-surgical technique that allows clinicians to prevent and correct malformations or injuries of a patient's spinal column. This review will explore the current standards of practice on spinal brace utilization. Specifically, it will highlight bracing usage in traumatic injuries, pregnancy, pediatrics, osteoporosis, and hyperkyphosis; address radiological findings concurrent with brace usage; and provide an overview of the braces currently available and advancements in the field. In doing so, we aim to improve clinicians' understanding and knowledge of bracing in common spinal pathologies to promote their appropriate use and improve patient outcomes.

A Dialogue With Professor Ellen Veomett: The Intersections Of Mathematics & Gerrymandering, Ellen Veomett

SMC Community Engagement

No abstract provided.

Can We Explain Machine Learning-Based Prediction For Rupture Status Assessments Of Intracranial Aneurysms?, Nan Mu, M. Rezaeitaleshmahalleh, Z. Lyu, M. Wang, J. Tang, C. M. Strother, J. J. Gemmete, A. S. Pandey, J. Jiang

Michigan Tech Publications, Part 1

Although applying machine learning (ML) algorithms to rupture status assessment of intracranial aneurysms (IA) has yielded promising results, the opaqueness of some ML methods has limited their clinical translation. We presented the first explainability comparison of six commonly used ML algorithms: multivariate logistic regression (LR), support vector machine (SVM), random forest (RF), extreme gradient boosting (XGBoost), multi-layer perceptron neural network (MLPNN), and Bayesian additive regression trees (BART). A total of 112 IAs with known rupture status were selected for this study. The ML-based classification used two anatomical features, nine hemodynamic parameters, and thirteen morphologic variables. We utilized permutation feature importance, …

Gardner-Webb Officials Announce Speaker For 2023 Commencement Ceremony, Office Of University Communications

Gardner-Webb NewsCenter Archive

Business executive and former N.C. Secretary of Commerce, Sharon Decker, will be the guest speaker for the Spring 2023 Commencement program at Gardner-Webb University. The traditional ceremony will take place on Thursday, May 4, at 7 p.m. in Spangler Stadium.

Finite Element Modeling Of Meniscal Tears Using Continuum Damage Mechanics And Digital Image Correlation, Derek Q. Nesbitt, Dylan E. Burruel, Bradley S. Henderson, Trevor J. Lujan

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Meniscal tears are a common, painful, and debilitating knee injury with limited treatment options. Computational models that predict meniscal tears may help advance injury prevention and repair, but first these models must be validated using experimental data. Here we simulated meniscal tears with finite element analysis using continuum damage mechanics (CDM) in a transversely isotropic hyperelastic material. Finite element models were built to recreate the coupon geometry and loading conditions of forty uniaxial tensile experiments of human meniscus that were pulled to failure either parallel or perpendicular to the preferred fiber orientation. Two damage criteria were evaluated for all experiments: …

Breeding Milestones Correspond With Changes To Wheat Rhizosphere Biogeochemistry That Affect P Acquisition, Rebecca Kay Mcgrail, David A. Van Sanford, David H. Mcnear Jr.

Plant and Soil Sciences Faculty Publications

Breeding wheat (Triticum aestivum L.) has resulted in small gains in improved nutrient acquisition and use as numerous traits are involved. In this study, we evaluated the impact of breeding on P-acquisition and identified both plant and soil variables that could be used to inform the selection of germplasm with increased P acquisition efficiency. We previously screened a historic panel of winter wheat cultivars for root system architecture and root tip organic acid content when grown in P-deficient solution/agar and used these characteristics together with breeding history to develop a predicted P extraction potential (PEP). We tested the validity …

Process Automation And Robotics Engineering For Industrial Processing Systems, Drake Stimpson

USF Tampa Graduate Theses and Dissertations

Automation in industrial systems applications has emerged as the fundamental solution for improving quality, production rate, and efficiency of a process. Much of the recent popularity surrounding the transition of processes from manually operated tasks to automated systems can be attributed to the concept of Industry 4.0, which outlines the fundamental guidelines for integrating cyber-physical systems into industrial processes. Due to rapid advancement of technology in robotics and automation as well as the increase in accessibility of resources to this technology, the capability to develop automated systems has become feasible for small-scale enterprise. This work presents a two-part initiative to …

Using Game Theory To Model Tripolar Deterrence And Escalation Dynamics, Grace Farson

Honors Program: Senior Projects (Public)

The study investigated how game theory can been utilized to model multipolar escalation dynamics between Russia, China, and the United States. In addition, the study focused on analyzing various parameters that affected potential conflict outcomes to further new deterrence thought in a tripolar environment.

A preliminary game theoretic model was created to model and analyze escalation dynamics. The model was built upon framework presented by Zagare and Kilgour in their work ‘Perfect Deterrence’. The model is based on assumptions and rules set prior to game play. The model was then analyzed based upon these assumptions using a form of mathematical …

Relative Impact Of Human & Natural Trauma On Psychological Functioning, Javeen Lynette Beard

Doctor of Psychology (PsyD)

Trauma, both natural and human induced, affects numerous people daily, often significantly impairing their quality of life. Human trauma and the subsequent quality of life has been extensively examined, but natural trauma remains largely overlooked. This study compares the quality of life following human and natural trauma. Because no suitable measure could be located, a 12-item Natural Disaster Assessment (NDA) was developed. Reponses were rated on a 7-point continuum from strongly agree to strongly disagree. Participants were recruited using Mechanical Turk. Among 136 participants, 56 were male (41.2%), 79 were female (58.1%), and one identified as other (0.7%). Participants completed …

Relationships Between Burnout, Isolation, Secondary Trauma, And Self-Compassion In Mental Health Providers, Michael Underriner

Doctor of Psychology (PsyD)

Experiencing burnout as a mental health provider is a growing concern with a number of personal and professional issues related to it; organizational and self-directed interventions are often used to combat the issue (Morse et al., 2012). With the onset of coronavirus (COVID-19), mental health providers face more isolation at work due to social distancing measures and more instances of hearing trauma reports from their patients. Self-compassion might be a solution to address the concerns stated above (McCade et al., 2021; Richardson et al, 2018). Participants in this study were members of a state psychological association, many of whom are …

Interactions Of Snps In Folate Metabolism Related Genes On Prostate Cancer Aggressiveness In European Americans And African Americans, Hui Yi Lin, Susan E. Steck, Indrani Sarkar, Elizabeth T.H. Fontham, Alan Diekman, Lora J. Rogers, Calvin T. Ratliff, Jeannette T. Bensen, James L. Mohler, L. Joseph Su

School of Public Health Faculty Publications

Background: Studies showed that folate and related single nucleotide polymorphisms (SNPs) could predict prostate cancer (PCa) risk. However, little is known about the interactions of folate-related SNPs associated with PCa aggressiveness. The study’s objective is to evaluate SNP–SNP interactions among the DHFR 19-bp polymorphism and 10 SNPs in folate metabolism and the one-carbon metabolism pathway associated with PCa aggressiveness. Methods: We evaluated 1294 PCa patients, including 690 European Americans (EAs) and 604 African Americans (AAs). Both individual SNP effects and pairwise SNP–SNP interactions were analyzed. Results: None of the 11 individual polymorphisms were significant for EAs and AAs. Three SNP–SNP …

A Candidate Magnetic Helium-Core White Dwarf In The Globular Cluster Ngc 6397, Manuel Pichardo Marcano, Liliana E. Rivera Sandoval, Thomas J. Maccarone, Rene D. Rohrmann, Craig O. Heinke, Diogo Belloni, Leandro G. Althaus, Arash Bahramian

Physics & Astronomy Faculty Publications

We report a peculiar variable blue star in the globular cluster (GC) NGC 6397, using Hubble Space Telescope optical imaging. Its position in the colour–magnitude diagrams and its spectrum are consistent with this star being a helium-core white dwarf (He WD) in a binary system. The optical light curve shows a periodicity at 18.5 h. We argue that this periodicity is due to the rotation of the WD and possibly due to magnetic spots on the surface of the WD. This would make this object the first candidate magnetic He WD in any GC, and the first candidate magnetic WD …

Sources Of Atmospheric Dust Deposition On Utah Lake, Justin Telfer

Theses and Dissertations

Atmospheric deposition (AD) is a significant source of nutrient loading to waterbodies around the world. However, the sources and loading rates are poorly understood for major waterbodies and even less understood for local waterbodies. Utah Lake is a eutrophic lake located in central Utah, USA, and has high nutrient levels. Recent research has identified AD as significant sources for nutrient loading to the lake to better understand the dust AD sources, we sampled suspected source locations and collected deposition samples around the lake. We analyzed these samples using Inductively Coupled Plasma (ICP) for 25 metals to characterize their elemental fingerprints. …