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Articles 173071 - 173100 of 1826870
Full-Text Articles in Entire DC Network
Product Specification: Distributed Trust Model System (Doe-Psu-0000922-4), Narmada Sonali Fernando, Abdullah Barghouti, Robert B. Bass, John M. Acken
Product Specification: Distributed Trust Model System (Doe-Psu-0000922-4), Narmada Sonali Fernando, Abdullah Barghouti, Robert B. Bass, John M. Acken
Electrical and Computer Engineering Faculty Publications and Presentations
A Distributed Trust Model (DTM) System is a supervisory component within an energy grid of things. The role of a DTM System is to implement the trust aspects of an energy services interface. The DTM System augments existing security measures by monitoring the communication between the various EGoT System actors and quantifying metrics of trust of each actor.
Dukungan Sosial Dari Orang Tua Asuh Kepada Anak Berhadapan Dengan Hukum Dalam Proses Rehabilitasi Sosial, Muhamad Rizky Hidayat, Annisah Annisah, Dwi Amalia Chandra Sekar
Dukungan Sosial Dari Orang Tua Asuh Kepada Anak Berhadapan Dengan Hukum Dalam Proses Rehabilitasi Sosial, Muhamad Rizky Hidayat, Annisah Annisah, Dwi Amalia Chandra Sekar
Jurnal Ilmu Kesejahteraan Sosial
The social rehabilitation process in which children face legal conflict is not easy, especially when they are far from their families. This article aims to examine the forms and benefits of social support from foster parents to Children in Conflict with the Law (ABH) who are undergoing the process of social rehabilitation. Descriptive qualitative research was conducted at the Social Rehabilitation Center for Children who Need Special Protection (BRSAMPK). This research was conducted in March-July 2021. Data collection was carried out through in-depth interviews with 13 informants, consisting of children in conflict with the law, heads of social services and …
Changes In Adult Well-Being And Economic Inequalities: An Exploratory Observational Longitudinal Study (2002–2010) Of Micro-Level Trends Among Tsimane’, A Small-Scale Rural Society Of Indigenous People In The Bolivian Amazon, Ricardo Godoy, Jonathan Bauchet, Jere R. Behrman, Tomás Huanca, William R. Leonard, Victoria Reyes-García, Asher Rosinger, Susan Tanner, Eduardo A. Undurraga, Ariela Zycherman
Changes In Adult Well-Being And Economic Inequalities: An Exploratory Observational Longitudinal Study (2002–2010) Of Micro-Level Trends Among Tsimane’, A Small-Scale Rural Society Of Indigenous People In The Bolivian Amazon, Ricardo Godoy, Jonathan Bauchet, Jere R. Behrman, Tomás Huanca, William R. Leonard, Victoria Reyes-García, Asher Rosinger, Susan Tanner, Eduardo A. Undurraga, Ariela Zycherman
Department of Agricultural Economics Faculty Publications
Knowing what happens over time to the lifeways of people in contemporary small-scale non-industrial societies of the rural Global South matters because it helps assess changes in the quality of life of underrepresented groups. It has been hard to answer the question because longitudinal information is rarely collected in such settings. A longitudinal dataset of nine years (2002–2010) from a horticultural-foraging society of Indigenous People in the Bolivian Amazon (Tsimane’) is used for an exploratory analysis of micro-level trends in indicators of well-being and economic inequalities. We selected 13 Tsimane’ villages (from ∼ 100) that varied in proximity to town …
Blue Whale And Krill Populations Modeling, Li Zhang
Blue Whale And Krill Populations Modeling, Li Zhang
CODEE Journal
We present an intriguing topic in an undergraduate mathematical modeling course where predator-prey models are taught to our students. We describe modeling activities and the use of technology that can be implemented in teaching this topic. Through modeling activities, students are expected to use the numerical and graphical methods to observe the qualitative long-term behavior of predator and prey populations. Although there are other choices of predators and prey, we find that using blue whales and krill as predator and prey, respectively, would be most beneficial in strengthening our students' awareness of protecting endangered species and its impact on climate …
Nonlinear Dynamics Of Mountain Pine Beetle Populations: Discussion Of Forestry Policy, A Survey Of Existing Mathematical Models, And Code Base Demonstration, Scott A. Strong, Maya Maes-Johnson
Nonlinear Dynamics Of Mountain Pine Beetle Populations: Discussion Of Forestry Policy, A Survey Of Existing Mathematical Models, And Code Base Demonstration, Scott A. Strong, Maya Maes-Johnson
CODEE Journal
This article presents existing mathematical models associated with mountain pine beetle populations in lodgepole pine forests, whose reproductive cycle requires the destruction of colonized host trees, decreasing timber availability/quality, and providing fuel sources for wildfires. With the existence of a positive-feedback loop with environmental warming, the need for intervention and management is clear. However, the legislative responses to the focusing events from our 2000-2010 North American epidemics are characterized as under-leveraged. While the reasons for this are multifaceted, increasing the capacity of STEM-informed individuals to take part in quantitative modeling of the underlying ecosystem generates awareness and provides pathways connecting …
Experimental Environmental Profiles And Sloshing Dynamics Aboard Zero-G Aircraft, Pedro J. Llanos, Sathya Gangadharan, Kevin Crosby
Experimental Environmental Profiles And Sloshing Dynamics Aboard Zero-G Aircraft, Pedro J. Llanos, Sathya Gangadharan, Kevin Crosby
Publications
This study presents the results of a parabolic flight experiment to study the sloshing dynamics of the magneto-active propellant management device experiment. This device utilizes a magnetoactive membrane and magnets located external to the tank to effectively damp the liquid free surface motion. This research work establishes a benchmark with sloshing analytical formulation and sensor calibration methods that can be used to characterize future research parabolic flights while providing important environmental profiles measured during flight, such as accelerations, pitch angle, velocity, temperature, total volatile content, carbon dioxide, relative humidity, magnetic field, and radiation. Correlation between these flight variables and the …
Experimental Analysis Of The Integrated High-Lift Propulsor, Robert W. Deters, Byron Ward, Shreyas Narsipur
Experimental Analysis Of The Integrated High-Lift Propulsor, Robert W. Deters, Byron Ward, Shreyas Narsipur
Publications
Wind tunnel testing was conducted to evaluate the performance of the Integrated High Lift Propulsor (IHLP), a novel Distributed Electric Propulsion (DEP) system. The IHLP integrates traditional Krueger flap/slat elements with a Distributed Electric Propulsion design, enhancing high lift performance and cruise efficiency compared to conventional pylon-mounted DEP configurations. Starting from a baseline configuration determined from pretest Computational Fluid Dynamics (CFD) analyses, a parametric study was performed to determine the influence on the aerodynamic characteristics (���� , ����, and ����). The study involved variations in flap settings, slat angles, overlap, propeller tilt, and propeller position. The impact of Reynolds number, …
Identifying Opportunities For Prevention Of Adverse Outcomes Following Female Genital Fistula Repair: Protocol For A Mixed-Methods Study In Uganda, Alison El Ayadi, Susan Obore, Fred Kirya, Suellen Miller, Abner Korn, Hadija Nalubwama, John Neuhaus, Monica Getahun, Patrick Eyul, Robert Twine, Erin Andrew, Justus Barageine
Identifying Opportunities For Prevention Of Adverse Outcomes Following Female Genital Fistula Repair: Protocol For A Mixed-Methods Study In Uganda, Alison El Ayadi, Susan Obore, Fred Kirya, Suellen Miller, Abner Korn, Hadija Nalubwama, John Neuhaus, Monica Getahun, Patrick Eyul, Robert Twine, Erin Andrew, Justus Barageine
Department of Obstetrics and Gynecology Faculty Papers
BACKGROUND: Female genital fistula is a traumatic debilitating injury, frequently caused by prolonged obstructed labor, affecting between 500,000-2 million women in lower-resource settings. Vesicovaginal fistula causes urinary incontinence, and other morbidity may occur during fistula development. Women with fistula are stigmatized, limit social and economic engagement, and experience psychiatric morbidity. Improved surgical access has reduced fistula consequences yet post-repair risks impacting quality of life and well-being include fistula repair breakdown or recurrence and ongoing or changing urine leakage or incontinence. Limited evidence on risk factors contributing to adverse outcomes hinders interventions to mitigate adverse events. This study aims to quantify …
Applying The Sir Model: Can Students Advise The Mayor Of A Small Community?, Carrin Goosen, Mark I. Nelson, Mahime Watanabe
Applying The Sir Model: Can Students Advise The Mayor Of A Small Community?, Carrin Goosen, Mark I. Nelson, Mahime Watanabe
CODEE Journal
This is an account of a modelling scenario that uses the sir epidemic model. It was used in a third year applied mathematics subject. All students were enrolled in a mathematics degree of some type. Students are presented with the results of a test carried out on 100 individuals in a community containing 3000 people. From this they determined the number of infectious and recovered individuals in the population. Given the per capita recovery rate and making a suitable assumption about the number of infectious individuals at the start of the epidemic, they then estimate the infectious contact rate and …
Profess 12 – Project Report Pr3: Briefing Document For Co-Creation Exercise, Una Beagon, Margaret Morgan, Ruchita Jani, Brian Bowe
Profess 12 – Project Report Pr3: Briefing Document For Co-Creation Exercise, Una Beagon, Margaret Morgan, Ruchita Jani, Brian Bowe
Reports
This document was prepared as a guide for co-creation exercises which are carried out with students to help design the PROFESS 12 Summer School. The briefing document has been prepared with information on how the co-creation exercise (in the form of a 2 hour workshop) will be facilitated and also includes background material which can be issued to students to prepare them for the event.
Fluid Flow, Mineralization And Deformation In An Oceanic Detachment Fault: Microtextural, Geochemical And Isotopic Evidence From Pyrite At 13°30′N On The Mid-Atlantic Ridge, Andrew J. Martin, John W. Jamieson, Sven Petersen, Mostafa Fayek, Javier Escartin
Fluid Flow, Mineralization And Deformation In An Oceanic Detachment Fault: Microtextural, Geochemical And Isotopic Evidence From Pyrite At 13°30′N On The Mid-Atlantic Ridge, Andrew J. Martin, John W. Jamieson, Sven Petersen, Mostafa Fayek, Javier Escartin
Geoscience Faculty Research
Hydrothermal fluids in ultramafic-hosted hydrothermal systems associated with oceanic detachment faults can be more oxidizing compared to mafic-hosted vent sites. These fluids form a mineral assemblage of pyrite, magnetite and hematite. At 13°30′N on the Mid-Atlantic Ridge, chlorite-quartz breccias recovered from an exposed fault scarp contain pyrite, with abundant magnetite and hematite, indicating that the redox of the fluids was variable. In primary micron-scale zonations in pyrite, Ni, Co, and Se have a decoupled relationship, recording fluctuations in the chemical composition and temperature of hydrothermal fluid as the grains grew. Secondary zonations that erase and overprint primary zonations are limited …
Implementation Profile: Modeling Environment (Doe-Psu-0000922-3), Sean Keene, Midrar Adham, Robert B. Bass
Implementation Profile: Modeling Environment (Doe-Psu-0000922-3), Sean Keene, Midrar Adham, Robert B. Bass
Electrical and Computer Engineering Faculty Publications and Presentations
This implementation profile provides the scope, background, and requirements necessary to implement a Modeling Environment (ME) to test a Distributed Energy Resource (DER) Management System (DERMS). A DERMS is used by an aggregator to dispatch large numbers of DERs in order to provide grid services to a Grid Operator. The ME addresses scalability issues inherent to Hardware-in-the-Loop DERMS simulation; a large number of assets are needed in order to observe effects on the grid from deployment and dispatch of DERs.
Energy Services Interface (Doe-Psu-0000922-1), Robert B. Bass
Energy Services Interface (Doe-Psu-0000922-1), Robert B. Bass
Electrical and Computer Engineering Faculty Publications and Presentations
This document defines a set of rules known as the Energy Services Interface (ESI), which “establish a bi-directional, service-oriented, logical interface to support secure, trustworthy information exchange between an aggregator and distributed energy resources (DERs). These exchanges facilitate energy interactions between the DERs and the aggregator, thereby allowing the aggregator to provide grid services through dispatch of the DERs.” The ESI serves as an umbrella, ensuring the information exchange between an aggregator and DER owners conforms to expectations: protect privacy, provide security, develop trustworthiness, and ensure interoperability. DERMS developers use the ESI to ensure that information exchange meets these expectations.
Assessing The Need For Pre-Mental Health Competencies In Undergraduate Education: Insights From Graduate Faculty Surveys, Kerstin K. Blomquist, Susan J. Wenze, C.J. Eubanks Fleming, Stephanie M. Ernestus
Assessing The Need For Pre-Mental Health Competencies In Undergraduate Education: Insights From Graduate Faculty Surveys, Kerstin K. Blomquist, Susan J. Wenze, C.J. Eubanks Fleming, Stephanie M. Ernestus
Open Access Fund Publications
Introduction: Despite the value of clinical competencies for masters- and doctoral-level practitioners as well as the tremendous variability in preparedness for graduate school and at graduation from graduate school, there are no competency standards for students pursuing mental healthcare careers prior to graduate study. This study aimed to identify potential pre-mental health competency standards for undergraduates pursuing mental healthcare careers.
Methods: Faculty at masters and doctoral programs in a range of mental healthcare fields were asked to rate their expectations of entry-level competence and the perceived entry-level competence of their first-year, bachelor-level graduate students on 42 sub-competencies derived from the …
To Open Or Not To Open: Developing A Covid-19 Model Specific To Small Residential Campuses, Christina Joy Edholm, Maryann Hohn, Nicole Lee Falicov, Emily Lee, Lily Natasha Wartman, Ami Radunskaya
To Open Or Not To Open: Developing A Covid-19 Model Specific To Small Residential Campuses, Christina Joy Edholm, Maryann Hohn, Nicole Lee Falicov, Emily Lee, Lily Natasha Wartman, Ami Radunskaya
CODEE Journal
In May 2020, administrators of residential colleges struggled with the decision of whether or not to open their campuses in the Fall semester of 2020. To help guide this decision, we formulated an ODE model capturing the dynamics of the spread of COVID-19 on a residential campus. In order to provide as much information as possible for administrators, the model accounts for the different behaviors, susceptibility, and risks in the various sub-populations that make up the campus community. In particular, we start with a traditional SEIR model and add compartments representing relevant variables, such as quarantine compartments and a hospitalized …
Solar Panels, Euler’S Method And Community-Based Projects: Connecting Differential Equations With Climate Change, Victor J. Donnay
Solar Panels, Euler’S Method And Community-Based Projects: Connecting Differential Equations With Climate Change, Victor J. Donnay
CODEE Journal
How does mathematics connect with the search for solutions to the climate emergency? One simple connection, which can be explored in an introductory differential equations course, can be found by analyzing the energy generated by solar panels or wind turbines. The power generated by these devices is typically recorded at standard time intervals producing a data set which gives a discrete approximation to the power function $P(t)$. Using numerical techniques such as Euler’s method, one can determine the energy generated. Here we describe how we introduce the topic of solar power, apply Euler’s method to determine the energy generated, and …
Using A Sand Tank Groundwater Model To Investigate A Groundwater Flow Model, Christopher Evrard, Callie Johnson, Michael A. Karls, Nicole Regnier
Using A Sand Tank Groundwater Model To Investigate A Groundwater Flow Model, Christopher Evrard, Callie Johnson, Michael A. Karls, Nicole Regnier
CODEE Journal
A Sand Tank Groundwater Model is a tabletop physical model constructed of plexiglass and filled with sand that is typically used to illustrate how groundwater water flows through an aquifer, how water wells work, and the effects of contaminants introduced into an aquifer. Mathematically groundwater flow through an aquifer can be modeled with the heat equation. We will show how a Sand Tank Groundwater Model can be used to simulate groundwater flow through an aquifer with a no flow boundary condition.
Comment On 'From Counterportation To Local Wormholes', Justin Dressel, Gregory Reznick, Lev Vaidman
Comment On 'From Counterportation To Local Wormholes', Justin Dressel, Gregory Reznick, Lev Vaidman
Mathematics, Physics, and Computer Science Faculty Articles and Research
Hatim Salih discovered a method for transferring a quantum state with no particles present in the transmission channel, which he named counterportation. Recently (Salih 2023 Quantum Sci. Technol.8 025016), he presented a feasible procedure for its implementation. The modification of the protocol by Aharonov and Vaidman, adopted by Salih, justifies the claim that no photons were present in the transmission channel during counterportation. We argue, however, that there is an error in this paper. The analysis of a simplified protocol, which questions the validity of the two-state vector formalism description of the photon presence in the communication channel, is …
Priority Skills For Engineers On The Island Of Ireland: Key Stakeholder Perceptions, Rosalind M Henry, Margaret Morgan, Una Beagon, Ruchita Jani, Janet Mckennedy, Brian Bowe
Priority Skills For Engineers On The Island Of Ireland: Key Stakeholder Perceptions, Rosalind M Henry, Margaret Morgan, Una Beagon, Ruchita Jani, Janet Mckennedy, Brian Bowe
Reports
Executive Summary
Life on a shared island, in particular the island of Ireland (comprising Ireland and Northern Ireland), presents both challenges and opportunities, including for engineers tasked with addressing problems to help solve the SDGs that are indifferent to boundaries. Research demonstrates that (relative to current engineers) the engineer of the future will require a more diverse range of skills to navigate an increasingly complex work environment. Given this context, identification of relevant priority skills would therefore prove useful in focusing engineering educational initiatives.
Building on a European study (Beagon et al, 2022a) which identified at a European level the …
Smartgrid-Ng: Blockchain Protocol For Secure Transaction Processing In Next Generation Smart Grid, Lokendra Vishwakarma, Debasis Das, Sajal K. Das, Christian Becker
Smartgrid-Ng: Blockchain Protocol For Secure Transaction Processing In Next Generation Smart Grid, Lokendra Vishwakarma, Debasis Das, Sajal K. Das, Christian Becker
Computer Science Faculty Research & Creative Works
With the advent of Blockchain and the Internet of Things (IoT), the Smart Grid is a rapidly growing technology in decentralized energy distribution and trading. However, this advancement came with some serious cyber security challenges and attacks, such as single-point failure due to a centralized architecture of smart grids, slow transaction processing, emerging cybersecurity threats, double-spending, fork, and fault tolerance. We propose a comprehensive framework for the smart grid called SmartGrid-NG to solve all these issues. Instead of using blockchain as a blackbox plugin tool, we also propose a reputation-based blockchain protocol called GridChain to increase the performance of blockchain-based …
Splitfed-Based Patient Severity Prediction And Utility Maximization In Industrial Healthcare 4.0, Himanshu Singh, Biken Moirangthem, Ajay Pratap, Shilpi Kumari, Abhishek Kumar, Sajal K. Das
Splitfed-Based Patient Severity Prediction And Utility Maximization In Industrial Healthcare 4.0, Himanshu Singh, Biken Moirangthem, Ajay Pratap, Shilpi Kumari, Abhishek Kumar, Sajal K. Das
Computer Science Faculty Research & Creative Works
The healthcare industry has transitioned from traditional healthcare 1.0 to AI-powered healthcare 4.0. However, overall cost for patient treatment remains high and challenging to manage due to the absence of a centralized cost evaluation mechanism before hospital visits. Therefore, in this paper, we devise a cloud-based mechanism to calculate hospitals' star rating based on questionnaire with the application of Z-score and K∗clustering algorithm. To evaluate disease severity at cloud, splitfed technique is utilized in coordination with Wireless Body Area Network (WBAN). Finally, the cloud calculates provisional treatment costs and finds a preferable hospital with a low payable treatment cost and …
Soil Carbon And Nitrogen After Eight Years Of Rotational Grazing In The Nebraska Sandhills Meadows, Gandura O. Abagandura, Martha Mamo, W. H. Schacht, Aaron Shropshire, Jerry Volesky
Soil Carbon And Nitrogen After Eight Years Of Rotational Grazing In The Nebraska Sandhills Meadows, Gandura O. Abagandura, Martha Mamo, W. H. Schacht, Aaron Shropshire, Jerry Volesky
Department of Agronomy and Horticulture: Faculty Publications
Grassland provides many ecosystem services; therefore, sustainable management practices of grassland are crucial for maintaining and enhancing its ecosystem health and resilience. Rotational grazing at a high stocking density (a.k.a., ultrahigh stocking density) is purported to sequester greater amounts of carbon (C) in grassland soils than rotational grazing at low stocking densities. This study was conducted in the Nebraska Sandhills meadows for eight years to evaluate how rotational grazing with different stocking densities can affect soil C and total nitrogen (TN) in bulk soils, soil organic matter fractions, and sequestration rate. The grazing management included a high stocking density with …
Unpacking Challenges And Reinforcing Evaluations In Bilateral And Multilateral Development Organizations In Egypt, Fatema Elghonemy
Unpacking Challenges And Reinforcing Evaluations In Bilateral And Multilateral Development Organizations In Egypt, Fatema Elghonemy
Theses and Dissertations
The research examines evaluations conducted in bilateral and multilateral development organizations considering programs that are funded by governments or international organizations. The Egyptian Government partners with development partners to receive technical assistance in various fields, such as industrial development, technical education, environmental protection, health improvement and refugees’ empowerment. The thesis explores the interlinkage between the development goals and the results framework to achieve sustainable development goals (SDGs). It then goes on to examine the evolution of the function of evaluation and its historical development into becoming a standalone field that serves the decision making, extension and expansion of interventions. As …
Audiologic And Vestibular Testing And Interpretation Of Outcome Data: A Case Series, Kelly Sarhage, Antony Joseph
Audiologic And Vestibular Testing And Interpretation Of Outcome Data: A Case Series, Kelly Sarhage, Antony Joseph
AuD Capstone Projects - Communication Sciences and Disorders
Abstract 1- Introduction: Nonorganic hearing loss is not typically associated with a detectable pathology.Both adults and children can present to the clinic with nonorganic hearing loss. It is often the result of psychosocial stressors and is more common in children, specifically 6 to 19 years old. Case Presentation: An 11-year-old child presented to the clinic with bilateral mild to moderate sensorineural hearing loss, but prior exams showed unilateral hearing loss on the left side. Discussion: Audiologists need to obtain a detailed case history, determine any underlying complications, inquire about additional auditory diagnoses, and employ objective testing to ascertain test reliability. …
On Progress In Exploring Controlled Viscous Limit-Cycle Oscillations In Modified Glauert Airfoil, Ethan Deweese, Lap Nguyen, Erik Vataker, William Mackunis, Vladimir Golubev, Ron Efrati, Oksana Stalnov
On Progress In Exploring Controlled Viscous Limit-Cycle Oscillations In Modified Glauert Airfoil, Ethan Deweese, Lap Nguyen, Erik Vataker, William Mackunis, Vladimir Golubev, Ron Efrati, Oksana Stalnov
Publications
The paper reports on the progress in the development of a novel robust, nonlinear flow control technology that employs an array of synthetic-jet actuators (SJAs) embedded in 2-DOF, elastically mounted, optimized Modified Glauert (MG) airfoil design in order to control limit cycle oscillations (LCO) at low subsonic flow regimes. The focus here is on the conceptual design of the wind energy harvesting system that employs, e.g., a piezoelectric device to extract energy from plunging LCO, with the closed-loop controller being capable to sustain the required LCO amplitudes over a wide range of wind speeds. The current high-fidelity studies first include …
Uab Expert Offers Tips On How To Combat Loneliness And Isolation This Year, Anna Jones
Uab Expert Offers Tips On How To Combat Loneliness And Isolation This Year, Anna Jones
Browse All News
No abstract provided.
Faculty Go To Washington For Leadership Roles At Nsf, Matt Windsor
Faculty Go To Washington For Leadership Roles At Nsf, Matt Windsor
Browse All News
No abstract provided.
Designing A Convection-Cloud Chamber For Collision-Coalescence Using Large-Eddy Simulation With Bin Microphysics, Aaron Wang, Mikhail Ovchinnikov, Fan Yang, Silvio Schmalfuss, Raymond A. Shaw
Designing A Convection-Cloud Chamber For Collision-Coalescence Using Large-Eddy Simulation With Bin Microphysics, Aaron Wang, Mikhail Ovchinnikov, Fan Yang, Silvio Schmalfuss, Raymond A. Shaw
Michigan Tech Publications
Collisional growth of cloud droplets is an essential yet uncertain process for drizzle and precipitation formation. To improve the quantitative understanding of this key component of cloud-aerosol-turbulence interactions, observational studies of collision-coalescence in a controlled laboratory environment are needed. In an existing convection-cloud chamber (the Pi Chamber), collisional growth is limited by low liquid water content and short droplet residence times. In this work, we use numerical simulations to explore various configurations of a convection-cloud chamber that may intensify collision-coalescence. We employ a large-eddy simulation (LES) model with a size-resolved (bin) cloud microphysics scheme to explore how cloud properties and …
Integrator-Mediated Clustering Of Poised Rna Polymerase Ii Synchronizes Histone Transcription, Jeremy E Wilusz, David S Gilmour, Ruth Lehmann, Timothée Lionnet
Integrator-Mediated Clustering Of Poised Rna Polymerase Ii Synchronizes Histone Transcription, Jeremy E Wilusz, David S Gilmour, Ruth Lehmann, Timothée Lionnet
Faculty, Staff and Students Publications
Numerous components of the transcription machinery, including RNA polymerase II (Pol II), accumulate in regions of high local concentration known as clusters, which are thought to facilitate transcription. Using the histone locus of Drosophila nurse cells as a model, we find that Pol II forms long-lived, transcriptionally poised clusters distinct from liquid droplets, which contain unbound and paused Pol II. Depletion of the Integrator complex endonuclease module, but not its phosphatase module or Pol II pausing factors disperses these Pol II clusters. Consequently, histone transcription fails to reach peak levels during S-phase and aberrantly continues throughout the cell cycle. We …
Barbara Lucinda Gray
African American Funeral Programs
Funeral program for Brabara Gray. Service held on January 4, 2024 in Savannah, Georgia