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Change Management Strategies For Successfully Managing The Lack Of Critical National Infrastructure In The Nigerian Telecommunication Industry, Adedoyin Adeola Jan 2024

Change Management Strategies For Successfully Managing The Lack Of Critical National Infrastructure In The Nigerian Telecommunication Industry, Adedoyin Adeola

Walden Dissertations and Doctoral Studies

No abstract provided.


Phenomenology Of Incels With Aggrieved Entitlement Who Participate In Online Communities, Catherine Patterson-Sterling Jan 2024

Phenomenology Of Incels With Aggrieved Entitlement Who Participate In Online Communities, Catherine Patterson-Sterling

Walden Dissertations and Doctoral Studies

No abstract provided.


Peer Recovery Support Effects On Substance Abuse In Rural Outpatient Community Behavioral Health, Melissa Bruce Jan 2024

Peer Recovery Support Effects On Substance Abuse In Rural Outpatient Community Behavioral Health, Melissa Bruce

Walden Dissertations and Doctoral Studies

No abstract provided.


Fire Department Personnel Perspectives On Avoidable Emergency Medical Services Calls And Emergency Department Visits, Nathanial Render Jan 2024

Fire Department Personnel Perspectives On Avoidable Emergency Medical Services Calls And Emergency Department Visits, Nathanial Render

Walden Dissertations and Doctoral Studies

No abstract provided.


The Perceptions Of Single Parents Raising A Child Diagnosed With Attention Deficit Hyperactivity Disorder With Behavioral And Emotional Concerns, Peterann Marie Blackstock Jan 2024

The Perceptions Of Single Parents Raising A Child Diagnosed With Attention Deficit Hyperactivity Disorder With Behavioral And Emotional Concerns, Peterann Marie Blackstock

Walden Dissertations and Doctoral Studies

No abstract provided.


The Lived Experiences Of Military Contractors And Impact Of Stress On Their Perceived Productivity And Job Satisfaction During Covid-19 Mandated Telework, Laury Hales Jan 2024

The Lived Experiences Of Military Contractors And Impact Of Stress On Their Perceived Productivity And Job Satisfaction During Covid-19 Mandated Telework, Laury Hales

Walden Dissertations and Doctoral Studies

No abstract provided.


Minority Small Business Owner Perceptions Of Coronavirus Policies In Metropolitan Washington, Dc, Amara Omar Kuyateh Jan 2024

Minority Small Business Owner Perceptions Of Coronavirus Policies In Metropolitan Washington, Dc, Amara Omar Kuyateh

Walden Dissertations and Doctoral Studies

No abstract provided.


Teachers’ Perceptions On The Use Of Behavior Management Software Programs To Encourage Positive Student Behavior, Carla Christine White Jan 2024

Teachers’ Perceptions On The Use Of Behavior Management Software Programs To Encourage Positive Student Behavior, Carla Christine White

Walden Dissertations and Doctoral Studies

No abstract provided.


Molecular And Clinical Effects Of Aromatase Inhibitor Therapy On Skeletal Muscle Function In Early-Stage Breast Cancer, Tara A Seibert, Lei Shi, Sandra Althouse, Richard Hoffman, Bryan P Schneider, Cody A Altherr, Theresa A Guise, Andrew R Coggan, Tarah J Ballinger Jan 2024

Molecular And Clinical Effects Of Aromatase Inhibitor Therapy On Skeletal Muscle Function In Early-Stage Breast Cancer, Tara A Seibert, Lei Shi, Sandra Althouse, Richard Hoffman, Bryan P Schneider, Cody A Altherr, Theresa A Guise, Andrew R Coggan, Tarah J Ballinger

Faculty, Staff and Student Publications

We evaluated biochemical changes in skeletal muscle of women with breast cancer initiating aromatase inhibitors (AI), including oxidation of ryanodine receptor RyR1 and loss of stabilizing protein calstabin1, and detailed measures of muscle function. Fifteen postmenopausal women with stage I-III breast cancer planning to initiate AI enrolled. Quadriceps muscle biopsy, dual-energy x-ray absorptiometry, isokinetic dynamometry, Short Physical Performance Battery, grip strength, 6-min walk, patient-reported outcomes, and serologic measures of bone turnover were assessed before and after 6 months of AI. Post-AI exposure, oxidation of RyR1 significantly increased (0.23 ± 0.37 vs. 0.88 ± 0.80, p <  0.001) and RyR1-bound calstabin1 significantly decreased (1.69 ± 1.53 vs. 0.74 ± 0.85, p <  0.001), consistent with dysfunctional calcium channels in skeletal muscle. Grip strength significantly decreased at 6 months. No significant differences were seen in isokinetic dynamometry measures of muscle contractility, fatigue resistance, or muscle recovery post-AI exposure. However, there was significant correlation between oxidation of RyR1 with muscle power (r = 0.60, p = 0.02) and muscle fatigue (r = 0.57, p = 0.03). Estrogen deprivation therapy for breast cancer resulted in maladaptive changes in skeletal muscle, consistent with the biochemical signature of dysfunctional RyR1 calcium channels. Future studies will evaluate longer trajectories of muscle function change and include other high bone turnover states, such as bone metastases.


China Maritime Report No. 34: Plan Submarine Training In The "New Era", Christopher Sharman, Terry Hess Jan 2024

China Maritime Report No. 34: Plan Submarine Training In The "New Era", Christopher Sharman, Terry Hess

CMSI China Maritime Reports

Since 2018, there have been significant changes to People’s Liberation Army Navy (PLAN) submarine force training, and these changes have been driven by important revisions to strategic guidance and subsequent directives that focused PLA efforts to enhance its capabilities to operate in the maritime domain. While this guidance is applicable to all services, improving PLAN submarine force capabilities appears to have been of particular interest to senior Chinese leadership. This guidance expanded the PLA’s maritime domain requirements, which demanded that China’s submarine force improve its capabilities to operate independently or along with other PLAN assets at greater distances from coast …


Assessing The Coherence In Biological And Environmental Drivers Of Young Sea Bass Abundance Across Important Estuarine Nursery Areas Of The Northern European Sea Bass Stock, Joseph W. Watson, Zachary Radford, Hayley Bannister, Robin Bradley, Mary Brown, Benjamin J. Ciotti, Derek Goodwin, Jennifer A. Graham, Richard D.M. Nash, William K. Roche, Ciara Wogerbauer, Kieran Hyder Jan 2024

Assessing The Coherence In Biological And Environmental Drivers Of Young Sea Bass Abundance Across Important Estuarine Nursery Areas Of The Northern European Sea Bass Stock, Joseph W. Watson, Zachary Radford, Hayley Bannister, Robin Bradley, Mary Brown, Benjamin J. Ciotti, Derek Goodwin, Jennifer A. Graham, Richard D.M. Nash, William K. Roche, Ciara Wogerbauer, Kieran Hyder

School of Biological and Marine Sciences

Year class strength is an important determinant of fish population size, but the drivers are often unknown. The northern stock of European sea bass (Dicentrarchus labrax) is an important target species for both commercial and recreational fisheries. Scientific assessments showed a rapid decline in spawning stock biomass from 2010-18 attributed to a combination of fishing mortality and poor year class strength. Recruitment to the adult stock is linked to the abundance and temporal dynamics of young bass in estuarine nursery areas, but little is known about the relative importance of environmental and biological drivers on the survival of these young …


On Quantifying Global Carbon Emission From Oil Contaminated Lands Over Centuries, Kaveh Sookhak Lari, Greg B. Davis, Trevor Bastow, John L. Rayner Jan 2024

On Quantifying Global Carbon Emission From Oil Contaminated Lands Over Centuries, Kaveh Sookhak Lari, Greg B. Davis, Trevor Bastow, John L. Rayner

Research outputs 2022 to 2026

Petroleum releases into the subsurface contribute to global soil carbon emissions. Quantifying releases and changes in releases of carbon from soils over the lifetime of a spill is complex. Natural source zone depletion (NSZD) of light non-aqueous phase liquids (LNAPLs) embodies all key mechanisms for transformation to carbon gases and their release from soils including partitioning, transport and degradation of petroleum components. Quantification of the interconnected behaviours of the soil microbiome, fluid flow, multi-component transport, partitioning, and biodegradation is crucial for understanding NSZD. Volatilization from LNAPL, aerobic biodegradation, methanogenesis, and heat production all lead to release of greenhouse gases to …


Brain-Based Classification Of Youth With Anxiety Disorders: Transdiagnostic Examinations Within The Enigma-Anxiety Database Using Machine Learning, Willem B. Bruin, Paul Zhutovsky, Guido A. Van Wingen, Janna Marie Bas-Hoogendam, Nynke A. Groenewold, Kevin Hilbert, Anderson M. Winkler, André Zugman, Federica Agosta, Fredrik Åhs Jan 2024

Brain-Based Classification Of Youth With Anxiety Disorders: Transdiagnostic Examinations Within The Enigma-Anxiety Database Using Machine Learning, Willem B. Bruin, Paul Zhutovsky, Guido A. Van Wingen, Janna Marie Bas-Hoogendam, Nynke A. Groenewold, Kevin Hilbert, Anderson M. Winkler, André Zugman, Federica Agosta, Fredrik Åhs

School of Medicine Publications

Neuroanatomical findings on youth anxiety disorders are notoriously difficult to replicate, small in effect size and have limited clinical relevance. These concerns have prompted a paradigm shift toward highly powered (that is, big data) individual-level inferences, which are data driven, transdiagnostic and neurobiologically informed. Here we built and validated supervised neuroanatomical machine learning models for individual-level inferences, using a case–control design and the largest known neuroimaging database on youth anxiety disorders: the ENIGMA-Anxiety Consortium (N = 3,343; age = 10–25 years; global sites = 32). Modest, yet robust, brain-based classifications were achieved for specific anxiety disorders (panic disorder), but …


Genome-Wide Study Investigating Effector Genes And Polygenic Prediction For Kidney Function In Persons With Ancestry From Africa And The Americas, Francois Aguet, Xiaoguang Xu, Girish Nadkarni, Quan Sun, Bridget M Lin, Thomas Gilliland, Mariah C Meyer, Jiawen Du, Laura M Raffield, Holly Kramer, Robert W Morton, Mateus H Gouveia, Elizabeth G Atkinson, Adan Valladares-Salgado, Niels Wacher-Rodarte, Nicole D Dueker, Xiuqing Guo, Yang Hai, Adebowale Adeyemo, Lyle G Best, Jianwen Cai, Guanjie Chen, Michael Chong, Ayo Doumatey, James Eales, Mark O Goodarzi, Eli Ipp, Marguerite Ryan Irvin, Minzhi Jiang, Alana C Jones, Charles Kooperberg, Jose E Krieger, Ethan M Lange, Matthew B Lanktree, James P Lash, Paulo A Lotufo, Ruth J F Loos, Vy Thi Ha My, Jesús Peralta-Romero, Lihong Qi, Leslie J Raffel, Stephen S Rich, Erik J Rodriquez, Eduardo Tarazona-Santos, Kent D Taylor, Jason G Umans, Jia Wen, Bessie A Young, Zhi Yu, Ying Zhang, Yii-Der Ida Chen, Tanja Rundek, Jerome I Rotter, Miguel Cruz, Myriam Fornage, Maria Fernanda Lima-Costa, Alexandre C Pereira, Guillaume Paré, Pradeep Natarajan, Shelley A Cole, April P Carson, Leslie A Lange, Yun Li, Eliseo J Perez-Stable, Ron Do, Fadi J Charchar, Maciej Tomaszewski, Josyf C Mychaleckyj, Charles Rotimi, Andrew P Morris, Nora Franceschini Jan 2024

Genome-Wide Study Investigating Effector Genes And Polygenic Prediction For Kidney Function In Persons With Ancestry From Africa And The Americas, Francois Aguet, Xiaoguang Xu, Girish Nadkarni, Quan Sun, Bridget M Lin, Thomas Gilliland, Mariah C Meyer, Jiawen Du, Laura M Raffield, Holly Kramer, Robert W Morton, Mateus H Gouveia, Elizabeth G Atkinson, Adan Valladares-Salgado, Niels Wacher-Rodarte, Nicole D Dueker, Xiuqing Guo, Yang Hai, Adebowale Adeyemo, Lyle G Best, Jianwen Cai, Guanjie Chen, Michael Chong, Ayo Doumatey, James Eales, Mark O Goodarzi, Eli Ipp, Marguerite Ryan Irvin, Minzhi Jiang, Alana C Jones, Charles Kooperberg, Jose E Krieger, Ethan M Lange, Matthew B Lanktree, James P Lash, Paulo A Lotufo, Ruth J F Loos, Vy Thi Ha My, Jesús Peralta-Romero, Lihong Qi, Leslie J Raffel, Stephen S Rich, Erik J Rodriquez, Eduardo Tarazona-Santos, Kent D Taylor, Jason G Umans, Jia Wen, Bessie A Young, Zhi Yu, Ying Zhang, Yii-Der Ida Chen, Tanja Rundek, Jerome I Rotter, Miguel Cruz, Myriam Fornage, Maria Fernanda Lima-Costa, Alexandre C Pereira, Guillaume Paré, Pradeep Natarajan, Shelley A Cole, April P Carson, Leslie A Lange, Yun Li, Eliseo J Perez-Stable, Ron Do, Fadi J Charchar, Maciej Tomaszewski, Josyf C Mychaleckyj, Charles Rotimi, Andrew P Morris, Nora Franceschini

Faculty, Staff and Students Publications

Chronic kidney disease is a leading cause of death and disability globally and impacts individuals of African ancestry (AFR) or with ancestry in the Americas (AMS) who are under-represented in genome-wide association studies (GWASs) of kidney function. To address this bias, we conducted a large meta-analysis of GWASs of estimated glomerular filtration rate (eGFR) in 145,732 AFR and AMS individuals. We identified 41 loci at genome-wide significance (p < 5 × 10−8), of which two have not been previously reported in any ancestry group. We integrated fine-mapped loci with epigenomic and transcriptomic resources to highlight potential effector genes relevant to kidney physiology and disease, and reveal key regulatory elements and pathways involved in renal function and development. We demonstrate the varying but increased predictive power offered by a multi-ancestry polygenic score for eGFR and highlight the importance of population diversity in GWASs and multi-omics resources to enhance opportunities for clinical translation for all.


Language And Material: The Life-World Of Ah-Q, Qinghua Cao Jan 2024

Language And Material: The Life-World Of Ah-Q, Qinghua Cao

Theoretical Studies in Literature and Art

The image of Ah-Q in Lu Xun's writing is not a carrier of any specific “characteristics”—be it national character or revolutionary spirit—but rather embodies a unique life-world. On the one hand, the individual living being of Ah-Q, who comes from the lowest social class, has been constructed and disciplined by the dominant language system of representation, of which he is also a maintainer and practitioner. On the other hand, he is also shaped by this system into a complete “other”, and is ultimately expelled and even eliminated by the system. As an “other”, Ah-Q's basic desires, rights and social positions …


Meet Scite, “Chatgpt For Research”, A New Artificial Intelligence (Ai) Tool Available Via Clemson Libraries, Jennifer Groff, Shelby Carroll Jan 2024

Meet Scite, “Chatgpt For Research”, A New Artificial Intelligence (Ai) Tool Available Via Clemson Libraries, Jennifer Groff, Shelby Carroll

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Hiccups And Hallucinations: Critically Engaging Ai In The Design Classroom, Drew Sisk Jan 2024

Hiccups And Hallucinations: Critically Engaging Ai In The Design Classroom, Drew Sisk

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


The Use And Misuse Of Generative Ai For Photos And Imagery, Erica B. Walker Jan 2024

The Use And Misuse Of Generative Ai For Photos And Imagery, Erica B. Walker

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Academic Ethics In Ai-Assisted Writing: A Writing Center-Informed Approach, John Falter Jan 2024

Academic Ethics In Ai-Assisted Writing: A Writing Center-Informed Approach, John Falter

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Navigating Anxiety And Activity: Generative Ai And Writing Support, Chelsea J. Murdock Jan 2024

Navigating Anxiety And Activity: Generative Ai And Writing Support, Chelsea J. Murdock

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Using Generative Artificial Intelligence For Engaged Student Learning, Janice G. Lanham, Charlotte Branyon Jan 2024

Using Generative Artificial Intelligence For Engaged Student Learning, Janice G. Lanham, Charlotte Branyon

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Ghostwriter To Co-Author: Helping Students Leverage Ai In The Classroom, Ishani Banerji Jan 2024

Ghostwriter To Co-Author: Helping Students Leverage Ai In The Classroom, Ishani Banerji

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Optimizing Ideation And Digital Prepress Workflows With Ai Integration, Carl N. Blue Jan 2024

Optimizing Ideation And Digital Prepress Workflows With Ai Integration, Carl N. Blue

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Requiring Students To Integrate Chatgptinto Course Assignments, Mark Small, Venera Balidemaj Jan 2024

Requiring Students To Integrate Chatgptinto Course Assignments, Mark Small, Venera Balidemaj

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Using Ai In The Teacher Preparation Programs And Social Studies Classrooms, Brandon Beck Jan 2024

Using Ai In The Teacher Preparation Programs And Social Studies Classrooms, Brandon Beck

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Language Portraits: A Space To Explore Identities In A Graduate Course, Hazel Vega Jan 2024

Language Portraits: A Space To Explore Identities In A Graduate Course, Hazel Vega

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Ai-Enhanced Education: Fostering Creativity, Efficiency, And Future-Ready Skills, Rodger Eugene Bishop Jan 2024

Ai-Enhanced Education: Fostering Creativity, Efficiency, And Future-Ready Skills, Rodger Eugene Bishop

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


Critical Ai Engagement: Crafting Assignments That Encourage Productive Engagement With Ai, Carl Ehrett Jan 2024

Critical Ai Engagement: Crafting Assignments That Encourage Productive Engagement With Ai, Carl Ehrett

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.


What Does It Mean To Talk About Tolkien And Diversity? A Look Within And Without The Legendarium, Yvette Kisor Jan 2024

What Does It Mean To Talk About Tolkien And Diversity? A Look Within And Without The Legendarium, Yvette Kisor

Journal of Tolkien Research

“What Does It Mean to Talk about Tolkien and Diversity? A Look within and without the Legendarium” considers racial diversity by focusing on the structure of Tolkien’s universe, both how it is modelled on ancient and medieval concepts like the Great Chain of Being and the Declining Ages of Man, but also remakes those models. In addition, it considers responses to racial structures perceived in Tolkien’s work.


Distress Alerting System, Tony England Visa, Nikhil Patil Visa Jan 2024

Distress Alerting System, Tony England Visa, Nikhil Patil Visa

Defensive Publications Series

The present disclosure provides a system and method for an automated, secure and reliable distress alerting system using which a user can alert their family/emergency contacts about their location and call for help. The proposed system uses a network to make available a facility/feature where the individual can tap a virtual card or a physical card on an electronic device (e.g., a Point of Sale (POS) device) such that the network identifies and differentiate this tap from a regular card transaction and route the request to a special section of the network where user has created an emergency contact. This …