Digital Commons Network^™

Budget Capping Health Care: Its Impact On Health, Susan Chen

Theses and Dissertations

The goal of a budget cap on healthcare is to constrain total healthcare expenditure without compromising quality. This paper examines the impacts of budget capping on health and behavioral health outcomes, exploiting the completed Maryland All-Payer Model and the ongoing, extensional Maryland Total Cost of Care model, both of which capped healthcare budgets in Maryland. I use data from 2011-2021 surveys of the Behavioral Risk Factor Surveillance system and generalized difference-in-difference regression models to find that budget capping improves health and behavioral health outcomes with a greater favorable effect during the Maryland Total Cost of Care model.

Scattered Fragments: Art, Architecture, And Archives In Revolutionary Urban Cairo, Mounira M. Makar

Theses and Dissertations

This thesis analyzes how revolutions impact urban Cairo and its communities, specifically within artistic, architectural and archival practice while acknowledging the central role of public spaces in giving way to such revolutionary practices. Fundamentally, this paper highlights the foundational nature of such practices in developing urban communities.

Lutz Bacher: 1975-2019, Jeremy Gloster

Theses and Dissertations

"Lutz Bacher: 1975-2019" is a monographic study of the artist Lutz Bacher (1943-2019), detailing the artist's trajectory from participant in the Bay Area photography scene of the mid-1970s to an established figure in the art world. Alongside this exposition, the thesis contends theoretically with Bacher's work, turning toward the theorist Peter Osborne's recent writings to examine Bacher's multifarious engagements with the photographic image and her own stagings of contemporaneity.

Stourhead In Arcadia Ego: The English Countryside And The Expanding British Empire In Eighteenth-Century, Rachel C. Sherr

Theses and Dissertations

Stourhead Gardens, an emblematic eighteenth-century landscape, reflects Britain's socio-cultural and imperial changes. Owned by the Hoare family, it melds classical influences and Enlightenment ideals. Existing research deciphers its iconography, but this thesis broadens the perspective, placing Stourhead in its era's socio-cultural context. It's a narrative rich in cultural and historical significance, shedding light on identity, art, and culture, past and present.

Learning From One’S Own Errors Vs From Observing Other People's Errors: Ego Engagement Vs Ego Threat, Viktoriya Andreevskaya

Theses and Dissertations

Do people learn better from their own errors or from observing other people’s errors? A sense of ego-threat may impede learning from negative corrective feedback directed to self. A series of two experiments manipulated the degree of ego-threat between subjects. In the neutral ego-threat condition, results showed better learning from self-generated errors.

Individual Concepts And Personal Identity Judgement, Molly M. Ye

Theses and Dissertations

Previous research into personal identity judgments has yielded conflicting outcomes. This paper introduces an alternative argument, proposing that the concept PERSON and HUMAN BEING provide different ways of thinking about the identity of people. Two experiments in this study provide evidence for this claim.

Macrocephaly And Digital Anomalies Expand The Phenotypic Spectrum Of Pgap2 Variants In Hyperphosphatasia With Impaired Intellectual Development Syndrome 3 (Hpmrs3), Seda Susgun, Afif Ben-Mahmoud, Franz Rüschendorf, Bonsu Ku, Syeda Iqra Hussain, Solveig Schulz, Oliver Puk, Saskia Biskup, Jonathan D.J. Labonne, Dilan Wellalage Don, Vijay Gupta, Tae Ik Choi, Saadullah Khan, Naveed Wasif, Yves Lacassie, Lawrence C. Layman, Sibel Aylin Ugur Iseri, Cheol Hee Kim, Hyung Goo Kim

School of Medicine Faculty Publications

Glycosylphosphatidylinositols (GPIs) anchor over 150 proteins as GPI-anchored proteins (GPI-APs) with crucial roles in diverse biological processes. The highly conserved biosynthesis of GPI-APs involves precise steps with at least 21 genes, categorized as PIG and PGAP genes. Pathogenic variants in these genes are linked to human diseases, highlighting the importance of each biosynthesis step. PGAP2 stands out among these genes due to its association with an expanded clinical spectrum of neurodevelopmental disorder (NDD) phenotypes with biallelic pathogenic variants. We present four patients from two families, one consanguineous and the other nonconsanguineous, each displaying distinct clinical presentations, including intellectual disability, hyperphosphatasia, …

Tillage And Cover Crop Systems Alter Soil Particle Size Distribution In Raised-Bed-And-Furrow Row-Crop Agroecosystems, Alayna A. Jacobs, Rachel Stout Evans, John K. Allison, William L. Kingery, Rebecca L. Mcculley, Kristofor R. Brye

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Conservation alternatives that include no-tillage (NT) and cover crops (CCs) reduce soil erosion in row-crop agroecosystems. However, little information is available about how these alternatives affect soil textural properties responsible for soil fertility. This study evaluated the soil particle size distribution and volumetric water content after three years of consistent management in a raised bed system. There were four treatment systems in a dryland maize/soybean rotation on a silt loam soil (Oxyaquic Fraglossudalfs) that included: NT + CCs, conventional tillage (CT) + CCs, CT + winter weeds, and CT + bare soil in winter in northwest Mississippi. The NT + …

Gwtc-2.1: Deep Extended Catalog Of Compact Binary Coalescences Observed By Ligo And Virgo During The First Half Of The Third Observing Run, R. Abbott, T. D. Abbott, F. Acernese, K. Ackley, Teviet Creighton, Mario C. Diaz, Francisco Llamas, Soma Mukherjee, Volker Quetschke, Wenhui Wang

Physics & Astronomy Faculty Publications

The second Gravitational-Wave Transient Catalog, GWTC-2, reported on 39 compact binary coalescences observed by the Advanced LIGO and Advanced Virgo detectors between 1 April 2019 15∶00 UTC and 1 October 2019 15∶00 UTC. Here, we present GWTC-2.1, which reports on a deeper list of candidate events observed over the same period. We analyze the final version of the strain data over this period with improved calibration and better subtraction of excess noise, which has been publicly released. We employ three matched-filter search pipelines for candidate identification, and estimate the probability of astrophysical origin for each candidate event. While GWTC-2 used …

Use Of Patient Diaries In Paediatric Intensive Care: Update Study. A Constructivist Grounded Theory Study Exploring The Child, Parents, And Healthcare Professionals’ Perspectives., Fiona Lynch

School of Nursing and Midwifery Theses

Use of Patient Diaries in pAediatric inTensive carE: UPDATE Study. A Constructivist Grounded Theory Study exploring the child, parents, and healthcare professionals’ perspectives. Fiona Lynch Paediatric Intensive Care Units (PICU) are essential to paediatric healthcare, providing high medical and nursing care to children who have become critically ill. PICUs offer prompt and appropriate interventions for children who have developed physiological instability, whether following surgery, from infection, trauma, or deterioration of a chronic condition. A stay in a PICU is not without potential psychological consequences for the child and family. Interventions to support recovery from the psychological impact of critical illness …

Exploring Functional Connectivity In Chronic Spinal Cord Injury Patients With Neuropathic Pain Versus Without Neuropathic Pain, Shreya Mandloi, Mashaal Syed, Isaiah Ailes, Omid Shoraka, Benjamin Leiby, J. Miao, Sara Thalheimer, Joshua Pelta-Heller, Feroze Mohamed, Ashwini Sharan, James Harrop, Laura Krisa, M. Alizadeh

Farber Institute for Neuroscience Faculty Papers

The great majority of spinal cord injury (SCI) patients have debilitating chronic pain. Despite decades of research, these pain pathways of neuropathic pain (NP) are unknown. SCI patients have been shown to have abnormal brain pain pathways. We hypothesize that SCI NP patients’ pain matrix is altered compared to SCI patients without NP. This study examines the functional connectivity (FC) in SCI patients with moderate-severe chronic NP compared to SCI patients with mild-no NP. These groups were compared to control subjects. The Neuropathic Pain Questionnaire and neurological evaluation based on the International Standard Neurological Classification of SCI were utilized to …

Synthesizing Physiology With Aquaculture For Olympia Oyster Restoration In Elkhorn Slough, Ca, Jacob Harris

Master's Theses

Conservation aquaculture is an emerging restoration strategy for depleted and low-density foundation species. It was recently applied for Olympia oysters in California. The only native oyster species is at risk of local extinction in much of its range. Conservation aquaculture can support oyster abundance, but long-term restoration success will be constrained by habitat conditions that suppress early growth and reproductive fitness. Following years of reproduction failure in Elkhorn Slough, CA, we examined these two critical life stages: juvenile and brooding. Our aim was to improve restoration by evaluating aquaculture methods and studying their physiology. We tested site parameters, oyster size, …

Critical-Size Defects Reconstruction With Four Different Bone Grafts Associated With E-Ptfe Membrane: A Histomorphometric Experimental In Vivo Study, Gustavo Fernandes, Filipe Castro, Rafael Martins Pereira, Wendel Teixeira, Sergio Gehrke, Julio Cesar Joly, Juan Blanco Carrion, Juliana Campos Hasse Fernandes

MOSDOH Faculty Publications

Objectives: The goal of this study was to assess the newly formed bone and the remnant biomaterial by comparing four different bone grafts used to treat critical-size defects, associated or not with the non-resorbable membrane.

Materials and methods: Two calvaria critical-size bone defects were created in 50 male Wistar rats. They were divided into blood (G1), autogenous (G2), bioglass (G3), hydroxyapatite (G4), and xenograft (G5) groups, associated or not with e-PTFE. The experimental periods were 15 and 45 days. Sections were prepared for histomorphometric assessment. All data were analyzed by the mixed-effects model with multiple comparisons (significance level, p < .05).

Results: …

Upi Guide I, Yoshihiko Ariizumi

Spiritual Proficiency

This book guides you to understand the basic theoretical foundation of this method (UPI or Chigen-iku).

Converting Mass And Energy Balance Chemical Engineering Concepts Into Fundamentals Of Environmental Engineering (Enve 210), Kaycie Lane

UNL Faculty Course Portfolios

This evaluation of teaching examined the Fall 2023 semester of ENVE 210: Fundamentals of Environmental Engineering. The purpose of this study was to change the format of the class from a lecture-based to a flipped classroom approach through the use of pre-lectures, in-class problem sets and group work activities. In addition, this study aimed to better adapt chemical engineering textbook content related to mass and energy balances to environmental engineering by creating new environmental engineering specific and sustainable development problems. The study learning outcomes proved difficult to implement and evaluate in a hybrid distance learning class and will require future …

Are Remote Health Clinics Primary Health Care Focused? Validation Of The Primary Health Care Engagement (Phce) Scale For The Australian Remote Primary Health Care Setting, Kylie Mccullough, Gemma Doleman, Melissa Dunham, Lisa Whitehead, Davina Porock

Research outputs 2022 to 2026

AIM: To test and validate a measure of primary health care (PHC) engagement in the Australian remote health context. BACKGROUND: PHC principles include quality improvement, community participation and orientation of health care, patient-centred continuity of care, accessibility, and interdisciplinary collaboration. Measuring the alignment of services with the principles of PHC provides a method of evaluating the quality of care in community settings. METHODS: A two-stage design of initial content and face validity evaluation by a panel of experts and then pilot-testing the instrument via survey methods was conducted. Twelve experts from clinical, education, management and research roles within the remote …

Access To Urban Leisure: Investigating Mobility Justice For Transgender And Gender Diverse People On Public Transport, Shahin Shakibaei, Oscar Vorobjovas-Pinta

Research outputs 2022 to 2026

Literature on mobility justice suggest that socially disadvantaged people experience uneven access to movement. The theme of diversity in terms of gender and its interplay with mobility and leisure have attracted some scholarly attention. However, research into transgender and gender diverse mobilities and its impact to leisure access remains limited, particularly from non-Western perspectives. This paper endeavors to fill this gap by investigating transgender and gender diverse mobilities in Istanbul, Turkey. Drawing upon 49 qualitative interviews with gender diverse and transgender public transport users in Istanbul, this study contributes to a scholarly discussion exploring the relationship between gender diversity, mobility, …

Stemdriver: A Knowledgebase Of Gene Functions For Hematopoietic Stem Cell Fate Determination, Kexin Huang, Yang Liu, Grant Wang, Ruihan Luo, Ting Niu, Yuzhou Feng, Haixia Xu, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

StemDriver is a comprehensive knowledgebase dedicated to the functional annotation of genes participating in the determination of hematopoietic stem cell fate, available at http://biomedbdc.wchscu.cn/StemDriver/. By utilizing single-cell RNA sequencing data, StemDriver has successfully assembled a comprehensive lineage map of hematopoiesis, capturing the entire continuum from the initial formation of hematopoietic stem cells to the fully developed mature cells. Extensive exploration and characterization were conducted on gene expression features corresponding to each lineage commitment. At the current version, StemDriver integrates data from 42 studies, encompassing a diverse range of 14 tissue types spanning from the embryonic phase to adulthood. In order …

Fusionpdb:: A Knowledgebase Of Human Fusion Proteins

Faculty, Staff and Student Publications

Tumorigenic functions due to the formation of fusion genes have been targeted for cancer therapeutics (i.e. kinase inhibitors). However, many fusion proteins involved in various cellular processes have not been studied for targeted therapeutics. This is because the lack of complete fusion protein sequences and their whole 3D structures has made it challenging to develop new therapeutic strategies. To fill these critical gaps, we developed a computational pipeline and a resource of human fusion proteins named FusionPDB, available at https://compbio.uth.edu/FusionPDB. FusionPDB is organized into four levels: 43K fusion protein sequences (14.7K in-frame fusion genes, Level 1), over 2300 + 1267 …

Ageannomo: A Knowledgebase Of Multi-Omics Annotation For Animal Aging, Haixia Xu, Qingxuan Li, Yuhao Jia, Liyu Huang, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

Aging entails gradual functional decline influenced by interconnected factors. Multiple hallmarks proposed as common and conserved underlying denominators of aging on the molecular, cellular and systemic levels across multiple species. Thus, understanding the function of aging hallmarks and their relationships across species can facilitate the translation of anti-aging drug development from model organisms to humans. Here, we built AgeAnnoMO (https://relab.xidian.edu.cn/AgeAnnoMO/#/), a knowledgebase of multi-omics annotation for animal aging. AgeAnnoMO encompasses an extensive collection of 136 datasets from eight modalities, encompassing 8596 samples from 50 representative species, making it a comprehensive resource for aging and longevity research. AgeAnnoMO characterizes …

Fusionneoantigen: : A Resource Of Fusion Gene-Specific Neoantigens, Xiaobo Zhou, Pora Kim

Faculty, Staff and Student Publications

Among the diverse sources of neoantigens (i.e. single-nucleotide variants (SNVs), insertions or deletions (Indels) and fusion genes), fusion gene-derived neoantigens are generally more immunogenic, have multiple targets per mutation and are more widely distributed across various cancer types. Therefore, fusion gene-derived neoantigens are a potential source of highly immunogenic neoantigens and hold great promise for cancer immunotherapy. However, the lack of fusion protein sequence resources and knowledge prevents this application. We introduce 'FusionNeoAntigen', a dedicated resource for fusion-specific neoantigens, accessible at https://compbio.uth.edu/FusionNeoAntigen. In this resource, we provide fusion gene breakpoint crossing neoantigens focused on ∼43K fusion proteins of ∼16K in-frame …

Cov2var, A Function Annotation Database Of Sars-Cov-2 Genetic Variation, Jianguo Wen, Weiling Zhao, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has resulted in the loss of millions of lives and severe global economic consequences. Every time SARS-CoV-2 replicates, the viruses acquire new mutations in their genomes. Mutations in SARS-CoV-2 genomes led to increased transmissibility, severe disease outcomes, evasion of the immune response, changes in clinical manifestations and reducing the efficacy of vaccines or treatments. To date, the multiple resources provide lists of detected mutations without key functional annotations. There is a lack of research examining the relationship between mutations and various factors such as disease severity, pathogenicity, patient age, patient gender, cross-species …

Drmref: Comprehensive Reference Map Of Drug Resistance Mechanisms In Human Cancer, Kexin Huang, Jiajia Liu, Grant Wang, Pora Kim, Qianqian Song, Xiaobo Zhou

Faculty, Staff and Student Publications

Drug resistance poses a significant challenge in cancer treatment. Despite the initial effectiveness of therapies such as chemotherapy, targeted therapy and immunotherapy, many patients eventually develop resistance. To gain deep insights into the underlying mechanisms, single-cell profiling has been performed to interrogate drug resistance at cell level. Herein, we have built the DRMref database (https://ccsm.uth.edu/DRMref/) to provide comprehensive characterization of drug resistance using single-cell data from drug treatment settings. The current version of DRMref includes 42 single-cell datasets from 30 studies, covering 382 samples, 13 major cancer types, 26 cancer subtypes, 35 treatment regimens and 42 drugs. All datasets in …

Justice Bork, Or, Be Careful Which Supreme Court Nominees You Choose To Fight, Mikel Norris

Political Science

This study uses counterfactual analysis to assess whether a hypothetical Supreme Court with Robert Bork as a member would have decided cases differently than the actual Supreme Court.

I utilize both a qualitative analysis, and a quantitative Bayesian counterfactual model to predict Supreme Court case outcomes from 1988 to 2012.

The results show that several salient cases would have been decided differently, most of the decisions decided over the time frame would have remained unchanged. I also find that a hypothetical Supreme Court with Robert Bork as an associate justice would not have radically shifted rightward. Rather, the results show …

Nuanced Impacts Of The Invasive Aquatic Plant Crassula Helmsii On Northwest European Freshwater Macroinvertebrate Assemblages, Samuel J.L. Tasker, Andrew Foggo, Kevin Scheers, Der Loop J Van, Salvatore Giordano, David T. Bilton

School of Biological and Marine Sciences

Invasive alien species are considered one of the greatest threats to global biodiversity, and are particularly problematic in aquatic systems. Given the foundational role of macrophytes in most freshwaters, alien aquatic plant invasions may drive strong bottom-up impacts on recipient biota. Crassula helmsii (New Zealand pygmyweed) is an Australasian macrophyte, now widespread in northwest Europe. Crassula helmsii rapidly invades small lentic waterbodies, where it is generally considered a serious threat to native biodiversity. The precise ecological impacts of this invasion remain poorly understood, however, particularly with respect to macroinvertebrates, which comprise the bulk of freshwater faunal biodiversity. We conducted a …

Examining The Role Of Mononormative Beliefs, Stigma, And Internalized Consensual Non-Monogamy Negativity For Dehumanization, David L. Rodrigues, Thomas R. Brooks, Rhonda N. Balzarini, Amy C. Moors, Diniz Lopes

Psychology Faculty Articles and Research

Interest in consensually non-monogamous (CNM) relationships has been increasing in the general population in recent years. However, given the cultural dominance of monogamy and the normative expectations often imposed through socialization (i.e., mononormativity), people in CNM relationships may experience negativity, which can become internalized and harm their individual and relationship health. The present study investigated if mononormativity beliefs and CNM relationship stigma were associated with more dehumanization and if internalized CNM negativity was an underlying mechanism for these associations. Results showed that participants who endorsed more mononormative beliefs and CNM relationship stigma also reported more internalized CNM negativity. In turn, …

Irrigation Of Sand-Based Creeping Bentgrass Putting Greens With Nanobubble-Oxygenated Water, Eric J. Deboer, Michael J. Richardson, John Mccalla

Horticulture Faculty Publications and Presentations

ultural and environmental factors can place creeping bentgrass (Agrostis stolonifera) under extreme stress during the summer months. This stress, coupled with the growth adaptation of creeping bentgrass, can result in shallow, poorly rooted stands of turf. To enhance root zone oxygen and rooting of creeping bentgrass, golf courses use methods such as core and solid-tine aerification, and sand topdressing. An additional method of delivering oxygen to the soil could be irrigation with nanobubble-oxygenated water. The properties of nanobubbles (NBs) allow for high gas dissolution rates in water. Irrigating with NB-oxygenated water sources may promote increased rooting of creeping …

Success In The Sciences: How The Library Can Support Student And Faculty Success In Scientific Disciplines, Justin Savage, Perri Moreno, Siobhan Mccarthy

University Libraries Scholarship and Creative Works

No abstract provided.

A Data-Driven Methodology To Comprehensively Assess Bone Drilling Using Radar Plots

Faculty, Staff and Student Publications

BACKGROUND: The study aims to develop a data-driven methodology to assess bone drilling in preparation for future clinical trials in residency training. The existing assessment methods are either subjective or do not consider the interdependence among individual skill factors, such as time and accuracy. This study uses quantitative data and radar plots to visualize the balance of the selected skill factors.

METHODS: In the experiment, straight vertical drilling was assessed across 3 skill levels: expert surgeons (N = 10), intermediate residents (postgraduate year-2-5, N = 5), and novice residents (postgraduate year-1, N = 10). Motion and force were measured for …

Ethnic Differences In Parental Experiences During The First Six Months After Picu Discharge In Singapore: A Qualitative Study, Pei Fen Poh, Matthew C. Carey, Joseph C. Manning, Jan Hau Lee, Jos M. Latour

School of Nursing and Midwifery

Introduction: Literature on parental experiences after childhood critical illness has limited representation from diverse ethnic backgrounds. Parents from global ethnic majority groups have reported worst psychological outcomes and required more social support after childhood critical illness. Aim: To explore the experiences of Chinese, Malay, and Indian parents in the first six months after Pediatric Intensive Care Unit (PICU) discharge of their child in Singapore. Methods: Sequential semi-structured qualitative interviews were conducted to collect data from a convenience sample of 28 parents at one month (n = 28) and at six months (n = 22) after their child's discharge from a …