Digital Commons Network^™

Student Perceptions Of Satisfactory Academic Progress Practices In Higher Education, Christopher Giovanni Rodriguez

Walden Dissertations and Doctoral Studies

No abstract provided.

Kinase-Impaired Btk Mutations Are Susceptible To Clinical-Stage Btk And Ikzf1/3 Degrader Nx-2127, Meghan C Thompson, Stefan Gajewski, Ying Siow May Tan, Stephanie Yung, Aleksandra Urban, Eric Wang, Cuijuan Han, Xiaoli Mi, Won Jun Kim, Quinlan Sievers, Paul Auger, Hugo Bousquet, Nivetha Brathaban, Brandon Bravo, Melissa Gessner, Cristiana Guiducci, James N Iuliano, Tim Kane, Ratul Mukerji, Panga Jaipal Reddy, Janine Powers, Mateo Sanchez Garcia De Los Rios, Jordan Ye, Carla Barrientos Risso, Daniel Tsai, Gabriel Pardo, Ryan Q Notti, Alejandro Pardo, Maurizio Affer, Vindhya Nawaratne, Tulasigeri M Totiger, Camila Pena-Velasquez, Joanna M Rhodes, Andrew D Zelenetz, Alvaro Alencar, Lindsey E Roeker, Sanjoy Mehta, Ralph Garippa, Adam Linley, Rajesh Kumar Soni, Sigrid S Skånland, Robert J Brown, Anthony R Mato, Gwenn M Hansen, Omar Abdel-Wahab, Justin Taylor

Faculty, Staff and Student Publications

INTRODUCTION:

Bruton’s tyrosine kinase (BTK) is a nonreceptor kinase in the B cell receptor (BCR) signaling cascade critical for B cell survival. As such, chronic lymphocytic leukemia (CLL) and other B cell cancers are sensitive to inhibition of BTK. Covalent and noncovalent inhibitors of BTK have revolutionized the treatment of these cancers. Therefore, understanding mechanisms by which acquired mutation in BTK confer drug resistance and developing new therapies to overcome resistance are critically important.

RATIONALE:

We recently discovered BTK mutations that confer resistance across covalent and noncovalent BTK inhibitors. In this study, we found that a group of these mutants …

Prenatal Exposure To Maternal Disadvantage-Related Inflammatory Biomarkers: Associations With Neonatal White Matter Microstructure, Ashley F P Sanders, Brian Tirado, Nicole A Seider, Regina L Triplett, Rachel E Lean, Jeffrey J Neil, J Philip Miller, Rebecca Tillman, Tara A Smyser, Deanna M Barch, Joan L Luby, Cynthia E Rogers, Christopher D Smyser, Barbara B Warner, Et Al.

2020-Current year OA Pubs

Prenatal exposure to heightened maternal inflammation has been associated with adverse neurodevelopmental outcomes, including atypical brain maturation and psychiatric illness. In mothers experiencing socioeconomic disadvantage, immune activation can be a product of the chronic stress inherent to such environmental hardship. While growing preclinical and clinical evidence has shown links between altered neonatal brain development and increased inflammatory states in utero, the potential mechanism by which socioeconomic disadvantage differentially impacts neural-immune crosstalk remains unclear. In the current study, we investigated associations between socioeconomic disadvantage, gestational inflammation, and neonatal white matter microstructure in 320 mother-infant dyads over-sampled for poverty. We analyzed maternal …

Exosome-Based Smart Drug Delivery For Cancer Treatment, Shabnam Malik, Mohammed Sikander, Sheema Khan, Daniel Zubieta, Murali M. Yallapu, Subhash C. Chauhan

School of Medicine Publications

Advances in nanoscale materials have become indispensable for targeted drug delivery, early detection, and personalized approaches for cancer treatment. Among various nanoscale materials investigated, exosomes hold significant promise in drug delivery. Exosomes are nanoscale vesicles that are usually 30–150 nm in size and produced by cells for intercellular communication. Due to their unique composition and inherent tumor-targeting capacity, these particles are well suited for tumor-specific delivery systems. This chapter discusses exosome isolation, therapeutic loading methods, key roles of exosomes in the tumor microenvironment, current applications of exosomes in drug delivery, and possible clinical implications.

Assessing Suboptimal Health Status In The Saudi Population: Translation And Validation Of The Shsq-25 Questionnaire, Mohamed A. Alzain, Collins O. Asweto, Sehar-Un-Nisa Hassan, Mohammed E. Saeed, Ahmed Kassar, Kamal E. M. Ali, Mouna Ghorbel, Rafat Zrieq, Bandar Alsaif, Wei Wang

Research outputs 2022 to 2026

Background: Suboptimal Health Status (SHS) is realised as a vital feature for improving global health. However, the Arabian world does not have a validated instrument for screening SHS in their population. Therefore, the study aimed to evaluate the psychometric properties of Arabic-translated SHS (ASHSQ-25) in the Saudi Arabian population. Methods: We conducted a cross-sectional study among the conveniently sampled 1590 participants from the Saudi population (with a 97.4% response rate). The data was gathered through an online survey and then exported into SPSS and AMOS version 26.0 for analysis. Mann-Whitney and Kruskal-Wallis tests were used to identify the median difference …

Covid-19 National Football League (Nfl) Injury Analysis: Follow-Up Study, Troy B. Puga, Joshua Schafer, Grace Thiel, Nicholas Scigliano, Tiffany Ruan, Andres Toledo, Prince N. Agbedanu, Kevin Treffer

Student Publications

Background:

In 2020, COVID-19 spread across the world and brought normal daily life to a halt, causing the shutdown of nearly everything in order to prevent its spread. The National Football League (NFL) similarly experienced shutdowns and the resulting effects, leaving athletes unable to train in some of the most advanced facilities with many of the best trainers in the world. A previous study, titled COVID-19 Return to Sport: NFL Injury Prevalence Analysis, determined that there was increased injury prevalence during the 2020 season, likely due to decreased physiological adaptations within athletes’ bodies as a result of facility shutdowns. …

Analysis Of The Impact Of Water Treatment By Liming Sedimentation And Dredging On The Content Of Heavy Metals In Fish Intended For Consumption, Asfie Maidie, Ismail Fahmy Almadi, Muchlis Efendi, Rekha Yusdha Nilawardhani, Komsanah Sukarti, Henny Pagoray

Journal of Sustainable Mining

The present study sought to determine the presence of metals and arsenic, a metalloid, among the fish of a coal mine reservoir, where the water was treated regularly through liming sedimentation combined with dredging, and the fish living in an adjoining river. The potential hazard of metals in fish as human food was analyzed. Except for selenium (an important metal to the human body), which was higher among the river fish than in the reservoir fish (P < 0.01), there were no particular patterns of other studied metals found in either habitat (P > 0.05), and apparently not related to the fish family that consumed by local people. Measurements of bioaccumulation factor (BAF) yielded scattered values from …

Antes Muerta Que Sencilla: Language And The Construction Of Feminine Beauty In The Spanish-Speaking World, Eva Michelle Wheeler

International Journal of the Linguistic Association of the Southwest

Much has been written on the topic of feminine beauty, and existing studies suggest that ideas about beauty are a powerful cultural mirror that reveal what we value as a society and how we are valued by society (e.g., Etcoff 1999; Rhodes 2006; Whitefield-Madrano 2016; Wolf 2002). Despite critical advances made in beauty research, few existing studies in this area explicitly examine the lexicon of beauty as a critical site of analysis (e.g., Démuth et al. 2022; Gladkova 2021; Gladkova & Romero-Trillo 2021; Miller & Stevens 2021; Tayebi 2021; Wong & Or 2021). In the context of Spanish, no existing …

Discursive Variation In Texas Spanish: A Dialectometric Approach, James Ramsburg

International Journal of the Linguistic Association of the Southwest

Texas Spanish has been characterized from a variety of perspectives, whether that be descriptively (Cardenas 1970), historically (Lipski 1988), and/or sociolinguistically (Chaston 1996, Martínez 2003, Bayley et al. 2012, Carter and Wolford 2016). However, to date, no study has sought to produce a dialectological account of Spanish discourse in Texas. By combining methods of quantitative and corpus linguistics, the present study seeks to investigate the dynamics of how Spanish discourse features, namely discourse markers and fillers, vary across multiple regions in Texas. To do so, this study utilizes a corpus of contemporary Texas Spanish (Bullock and Toribio 2013) and evaluates …

A 10-Year Retrospective Case Study Of The Relation Between Four Summative Assessment Measures In A Graduate Speech-Language Pathology Program, Lynne Cameron, Laurel Teller, Rebecca Throneburg, Nichole Mulvey, Jill Fahy

Teaching and Learning in Communication Sciences & Disorders

Assessment is essential to ensure that quality levels of teaching and learning are maintained in graduate programs in Communication Sciences and Disorders (CSD). In this article, we present a ten-year retrospective case study of one CSD master’s program approach to address speech-language pathology program-level summative assessment. We evaluated the strength of the relation between three departmental summative measures (i.e., Grand Rounds [Capstone Course] final grade percentages, Written Comprehensive examinations, Oral Comprehensive examinations) and the national Praxis Examination in Speech-Language Pathology (5331). The strongest correlations were between the Grand Rounds final grade percentages, Written Comprehensive examinations, and the Praxis. The weakest …

The Minority Student Mentoring Group (Msmg) For Csd Students: Perspectives, Goals, And Outcomes Six Years After Inception, Iona Ringgold, Diana C. Emanuel

Teaching and Learning in Communication Sciences & Disorders

Students from historically marginalized racial and ethnic (HMRE) groups often face challenges within the university environment due to implicit biases, microaggressions, and systemic racism. To help counteract these challenges, the Minority Student Mentoring Group (MSMG) at Towson University was launched in 2016 to provide mentoring, support, and a sense of community for students from HMRE groups who are enrolled in speech-language pathology and audiology programs. Rapid growth of the program and anecdotal evidence suggested MSMG participation was impactful; as a result, this study was designed to examine program outcomes more formally using a mixed-methods approach. Eleven participants completed an on-line …

Development Of Interprofessional Socialization In A Multifaceted Live Action Clinical Role-Play Simulation For Speech-Language Pathology And Social Work Students, Cody Marie Busch, Jennifer Anderson, Lynn Gilbertson, Sarah Hessenauer

Teaching and Learning in Communication Sciences & Disorders

Live action clinical role-plays are one of many types of simulated learning experiences that can be crafted for undergraduate and graduate students alike when learning to collaborate interprofessionally. This mixed methods exploratory research project partnered four academic instructors from the disciplines of speech-language pathology and social work, with several additional community members adding their expertise to enrich the experience of a live-action clinical role-play. Students (N = 32) participated in a two-part multifaceted interprofessional education (IPE) experience with the first part consisting of eight hours of online asynchronous training and the second part consisting of eight hours of a multifaceted …

Boosting Confidence In Hearing Loss Services Through An Interprofessional Simulation Led By Peer Instructors, Amanda Stead, Jordan Tinsley, Trent Westrick, Elizabeth Olson, Alexandra Alfieri, Lauren Sams

Teaching and Learning in Communication Sciences & Disorders

Speech-language pathologists have an ethical responsibility to work with clients with hearing loss. Therefore, speech-language pathology (SLP) students must receive specific education and training in working with this population. SLP students may have low self-efficacy about their ability to work with clients with hearing loss if they haven’t participated in specific training. Interprofessional education utilizing peer teaching by doctor of audiology (AuD) students is one method for helping SLP students learn specific skills to address hearing loss in a clinical setting. The purpose of this study was to investigate SLP graduate students' self-efficacy with working with individuals with hearing loss; …

Fostering Empathy In Communication Sciences And Disorders Through Interprofessional Simulation: Bridging The Gap Between Lecture And Practice, Cynthia A. Hovland, Carol Spears, Melissa Volk

Teaching and Learning in Communication Sciences & Disorders

This exploratory study sought to understand the experiences of CSD students participating in an interprofessional simulation focused on empathy development and how it could inform their future practice. This study used a non-random, purposive sample of 29 CSD students from one United States university who attended one of three Team STEPPS seminar training days that were offered during three separate semesters. Post-seminar surveys were completed, and conventional content analysis used to analyze data. Three primary themes, and corresponding subthemes emerged: (a) establish trust (build rapport; identify patient care goals; and encourage active participation; (b) facilitate collaborative plan of care (provide …

Addressing Bias In Slp Problem-Based Tutorials Through Critical Reflexivity, Curriculum Development And Instructor Training, Harmonie Chan, Courtney Tidd, Justine Hamilton, Deidre Sperry, Michelle Phoenix

Teaching and Learning in Communication Sciences & Disorders

Racism is prevalent in the fields of healthcare and education in North America and speech-language pathology and audiology are no exception. Systemic and individual racism in educational, training, and clinical settings creates barriers for student entry and success, and negatively impacts client care. Although the ability to serve clients of diverse backgrounds is a crucial skill for students and clinicians, current educational curricula appears insufficient in supporting culturally diverse students and preparing all students to work with culturally diverse populations. This is, in part, due to a lack of diverse representation in education and clinical settings, bias experienced by SLP …

What Think Ye Of Man?, Earl Clement Davis

Sermons, 1905-1919

A concise statement of the divinity of man -- that Christ was a man and divine, as all men are divine and that it is through experience that each person learns the value of life.

Date refers to Date Given and The primary downloadable document contains the original document followed by the transcription.

The bottom of each item page also features the primary document as an embedded pdf for browsing.

Transcription by Davis Baird.Item description based off writing and context provided by Davis Baird.

Online Orientation Course: A Predictor Of New Student Persistence And Academic Success, Manicone A. Hailey Ed.D., Dwayne Melton D.B.A., Brian Yates Ed.D.

Journal of Access, Retention, and Inclusion in Higher Education

No abstract provided.

The Urgency In Legal Protection Of The Internment In Non-International Armed Conflict Between The Ethiopian Government And The Tigray People’S Liberation Front, Ika Ningtyas, Maheswari Trinanda Putri, Yasniar Rachmawati, Fransiska A. Susanto, Patricia Audrey Ruslijanto

Indonesian Journal of International Law

The issue of a legal vacuum in international humanitarian law related to administrative internment in non-international armed conflicts has been a concern addressed in Article 3 of the Geneva Convention and Articles 5-6 of Additional Protocol II. Due to this deficiency, many countries establish their domestic laws. One such example is the non-international armed conflict between the Ethiopian government and a non-state armed group, the Tigray People’s Liberation Front. The issue in this case began with the government's emergency statement for a six-month period, granting broad authority to arrest individuals based on “impossible judgment” and cooperation with a “terrorist group” …

Goldpinch Multi Dimensional Scrolling

Defensive Publications Series

The present disclosure generally relates to accessing digital content and, more particularly, selecting digital content via a user interface in a social media platform.

International Tribunals Approach Toward Maritime Boundaries Delimitation Of An Archipelagic State, Gulardi Nurbintoro

Indonesian Journal of International Law

One of the most prominent features of the United Nations Convention on the Law of the Sea (UNCLOS) is the recognition of the archipelagic State concept, embodied under Part IV of the Convention. Since the entry into force of the Convention, more than 20 countries have claimed archipelagic State status, all of which are developing countries. Despite the considerable number of archipelagic States and a universal recognition of the concept, judicial jurisprudence remains very limited, if not non-existent, with respect to practices of archipelagic States pertaining to maritime boundaries delimitation. Up to the writing of this abstract, only two maritime …

Conceptions Of Legitimacy Under International Human Rights Law And Islamic Rights Law, Raas Nabeel

Indonesian Journal of International Law

Islamic law, or the shariah, is a rich body of legal rules and obligations that aims to protect individuals from wrongs committed to each other and wrongs committed to God. However, Islamic law is often considered to be at odds with international human rights law, particularly in certain domains such as gender rights, the freedom of expression, the freedom of religion, and the right to dignity. Muslim-majority States have criticized the Universal Declaration of Human Rights, the International Bill of Rights, as well as other international human rights conventions for the seeming incompatibility of their obligations with the rules, practices, …

Today’S Mathematics Student: Take Two, Carmen M. Latterell

The Mathematics Enthusiast

Current mathematics students are members of Generation Z, a generation proving to be quite different than previous ones. Generation Z has never known a time without Google, nor a time of safety. Generation Z has a declining tendency to even attend college. If they do attend college, their expectations need to be met to keep them engaged in mathematics. Professors will need to adjust pedagogy.

Analyzing Global Utilization And Missed Opportunities In Debt-For-Nature Swaps With Generative Ai, Nataliya Tkachenko, Simon Frieder, Ryan-Rhys Griffiths, Christoph Nedopil

Sim Kee Boon Institute for Financial Economics

We deploy a prompt-augmented GPT-4 model to distill comprehensive datasets on the global application of debt-for-nature swaps (DNS), a pivotal financial tool for environmental conservation. Our analysis includes 195 nations and identifies 21 countries that have not yet used DNS before as prime candidates for DNS. A significant proportion demonstrates consistent commitments to conservation finance (0.86 accuracy as compared to historical swaps records). Conversely, 35 countries previously active in DNS before 2010 have since been identified as unsuitable. Notably, Argentina, grappling with soaring inflation and a substantial sovereign debt crisis, and Poland, which has achieved economic stability and gained access …

Reefer Madness

Theatre and Performance Studies Programs

Full program for Reefer Madness.

Conic Challenge: Pushing The Frontiers Of Nuclear Detection, Segmentation, Classification And Counting, Simon Graham, Quoc Dang Vu, Mostafa Jahanifar, Martin Weigert, Uwe Schmidt, Wenhua Zhang, Jun Zhang, Sen Yang, Jinxi Xiang, Xiyue Wang, Josef Lorenz Rumberger, Elias Baumann, Peter Hirsch, Lihao Liu, Chenyang Hong, Angelica I. Aviles-Rivero, Ayushi Jain, Heeyoung Ahn, Yiyu Hong, Hussam Azzuni, Min Xu

Computer Vision Faculty Publications

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using the largest available dataset of its kind to assess nuclear segmentation and cellular composition. Our challenge, named CoNIC, stimulated the development of reproducible algorithms for cellular recognition with real-time result inspection on public leaderboards. We conducted an extensive post-challenge analysis based on the top-performing models using 1,658 whole-slide images of colon tissue. With around 700 million detected nuclei per model, associated features were used for dysplasia grading and …

Using Natural Language Processing And Patient Journey Clustering For Temporal Phenotyping Of Antimicrobial Therapies For Cat Bite Abscesses, Brian Hur, Karin M. Verspoor, Timothy Baldwin, Laura Y. Hardefeldt, Caitlin Pfeiffer, Caroline Mansfield, Riati Scarborough, James R. Gilkerson

Natural Language Processing Faculty Publications

Background: Temporal phenotyping of patient journeys, which capture the common sequence patterns of interventions in the treatment of a specific condition, is useful to support understanding of antimicrobial usage in veterinary patients. Identifying and describing these phenotypes can inform antimicrobial stewardship programs designed to fight antimicrobial resistance, a major health crisis affecting both humans and animals, in which veterinarians have an important role to play. Objective: This research proposes a framework for extracting temporal phenotypes of patient journeys from clinical practice data through the application of natural language processing (NLP) and unsupervised machine learning (ML) techniques, using cat bite abscesses …

"I Live My Best Life In The Garden": Project Dig Summary Report, Tracy Boehm Barrett, University Of Montana Rural Institute

Health and Wellness

People with intellectual and developmental disabilities (IDD) are commonly overlooked in society because of a combination of social, economic, political, and cultural barriers. Due to such constraints, they also experience a wide range of health and community disparities that result in negative impact on their quality of life and well-being (Mpofu et al., 2020; Akyurek & Bumin, 2017). While many community-based organizations provide a variety of supports for people with disabilities, far less common are those providing therapeutic horticulture (TH) programs within the scope of their services. This report provides information about and recommendations for TH as an increased practice …

Field Assessment Form Evaluation Focusing On Updating For Student Success, Jenni Harding, Michelle Holmes, Brian C. Rose, Jody Lawrence, Hannah J. Kang, Kimberly A. Mahovsky

Assessment Mini Grant Reports

The purpose of this assessment mini grant was to evaluate and modify the Field Assessment Form (FAF) allowing us to better serve a diverse student population with integrity. The FAF was created and implemented a decade ago and thanks to this mini grant has been updated taking diversity, equity, and the progressive change of education into account.

The FAF is completed during practicum and student teaching experiences for students in the Early Childhood, undergraduate Professional Teacher Education, and graduate Professional Teacher Education programs. The FAF is a School of Teacher Education evaluation tool. The FAF is a rubric evaluation that …

An Active Learning Activity For The Construction Of A Finite-Field Slide Rule For Undergraduate Students, Marco Abrate

The Mathematics Enthusiast

Math manipulatives and physical math activities offer numerous benefits in the learning process in all educational levels: they provide concrete representations of abstract concepts, thus helping more students to understand them, and they are an opportunity for students to explore and test their understanding of mathematical concepts. Moreover, in active learning activities conducted with tangible objects, students are physically engaged in the lessons, and are given a fun way to practice their math skills, which contributes with retention and positive feeling.

In this article, an active teaching activity aimed at first-year college students is presented, designed to deepen the understanding …

Nymc Synapse Issue 42, School Of Medicine Student Senate, New York Medical College

The Synapse

No abstract provided.