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Collections Of Western Wheatgrass And Blue Grama And Associated Nematode Genera In The Western Dakotas, R E. Barker, J D. Berdahl, J M. Krupinsky, E T. Jacobson May 2026

Collections Of Western Wheatgrass And Blue Grama And Associated Nematode Genera In The Western Dakotas, R E. Barker, J D. Berdahl, J M. Krupinsky, E T. Jacobson

IGC Proceedings (1977-2023)

Western wheatgrass (Agropyron smithii Rydb.) and blue grama (Bouteloua gracilis[Willd. ex H.B.K.J Lag. ex Griffiths) are widely distributed throughout the U.S.A. They arc two of the predominant native grasses in rangelands in the northern Great Plains. Because suitable cultivars are not always available for reseeding disturbed areas, we collected plants of the two species and evaluated phenotypic variability to determine potential for breeding improvement. We also sampled the nematode popula­tion associated with the collections. Sampling sites were systematically chosen by establishing a grid pattern 19 .3 km apart in the western halves of North Dakota and South Dakota. …


Neutral Detergent Fiber And Protein Levels In Diploid And Tetraploid Ryegrass Forage, L R. Nelson, F M. Rouquette Jr May 2026

Neutral Detergent Fiber And Protein Levels In Diploid And Tetraploid Ryegrass Forage, L R. Nelson, F M. Rouquette Jr

IGC Proceedings (1977-2023)

Nutritive value of 18 ryegrass (Lolium multifloriumLam.) cultivars was studied at Overton, Te1

0.42-mm screen. Plots were harvested four times during each of the first 2 years and five times in the third year. In 1977-1978 and 1978-1979, NDF and protein analyses were run on samples from 2 replications. All forage samples were analyzed for pro­tein via the micro-Kjeldahl technique. Percentages of NDF were obtained via Van Soest extraction procedures. A seasonal increase in neutral detergent fiber (NDF) content and a decrease in protein percentage was observed. Differences in NDF were observed among cultivars and were most apparent during …


Forage Quality Of Barley Straw As Influenced By Genotype, D W. Meyer, D O. Erickson, A E. Foster May 2026

Forage Quality Of Barley Straw As Influenced By Genotype, D W. Meyer, D O. Erickson, A E. Foster

IGC Proceedings (1977-2023)

Cereal straw is an untapped carbohydrate source for ruminant animal feeds, but little information is available on genotypic differences in the feeding value of barleys (Hordeum vulgare L.) commonly grown in the northern Great Plains of the U.S.A. Our objective was to determine if barley genotypes differ in straw forage quality and if straw-quality parameters are associated with agronomic characters. Straw from 37 and 31 barley genotypes was sampled in 1977 and 1978, respectively. Straw from 10 barley genotypes grown at four locations was sampled in 1979. Standard laboratory procedures were used to determine the quality parameters measured. Correlations …


Alfalfa Breeding For Forage Yield And Low Saponin Content, P Rotili May 2026

Alfalfa Breeding For Forage Yield And Low Saponin Content, P Rotili

IGC Proceedings (1977-2023)

The objective of our breeding program is to build alfalfa (Medicago satia L.) varieties, having good vigor and persistence, high protein level, and low ,aponin content. The: breeding method utilizes a selfing phase combined with selection in competitive conditions. Leaf-saponin content was analyzed by the Tn'choderma viridc bioassay. Parent populations (cv. Leonicena and Cantoni), S0, S1., and S2, families :1 were evaluated 11ndcr competitive and &equcnt culling conditions. In both populations, some S1, families yield more than their respective S1 family. Vuiatioo in yield and mortality increased with the level of selfing, and 1ome S2 families showed lower minimum values …


Productivity Of Forage Legumes On Rice-Paddy Walls In Northeast Thailand, R G. Gutteridge May 2026

Productivity Of Forage Legumes On Rice-Paddy Walls In Northeast Thailand, R G. Gutteridge

IGC Proceedings (1977-2023)

Rice stubble left standing in paddy fields after rice harvest is the major source of forage for livestock in the dry season in northeast Thailand. Although the quantity of thi5 1tubble is generally not limiting, its quality as a forage is very low, and substantial live-weight losses in livestock usually occur by the end of the dry season. A trial was conducted to evaluate a range of forage legumes that could be grown on rice-paddy walls to supplement rice stubble as a dry-season feed. Seven legumes were planted at two sites in villages close to Khon Kaen in northeast Thailand. …


Development Of Gama Medic {Medicago Rugosa Desr.) As An Annual Leguminous Species For Dryland Farming Systems In Southern Australia, E J. Crawford May 2026

Development Of Gama Medic {Medicago Rugosa Desr.) As An Annual Leguminous Species For Dryland Farming Systems In Southern Australia, E J. Crawford

IGC Proceedings (1977-2023)

Annual medics (Medicago spp.) are the basic legume for nitrogen fixation in the alkaline soils of southern Australia. Not all in­dividual species are well adapted to all soil types, one difficult soil being the highly alkaline clay loam where annual rainfall is less than 500 mm. The first gama medic (M. rugosa) cultivar, Paragosa, was well adapted to the clay-loam soil type but proved to be susceptible to germination after summer thunderstorms, and seedlings died in the following drought. Many gama medic accessions were then grown in an attempt to select a genotype capable of maintaining seedcoat impermeability during …


Evolution Of Selection Techniques In Breeding For Bloat-Safe Alfalfa, B P. Goplen, R E. Howarth, G L. Lees, W Majak, J P. Fay, K J. Cheng May 2026

Evolution Of Selection Techniques In Breeding For Bloat-Safe Alfalfa, B P. Goplen, R E. Howarth, G L. Lees, W Majak, J P. Fay, K J. Cheng

IGC Proceedings (1977-2023)

This report summarizes the Canadian breeding program to develop a bloat-safe alfalfa (Medicago sativa L.). This program has experienced an evolution of selection methods in attempting to identify bloat-safe alfalfa genotypes. In chronological order, the methods involved selection for fraction I (18S) protein, soluble proteins, foam volume, tannins (flavolans), saponins, initial rate of digestion (IRD), sonication, purified enzymes, gas production, and leaching. Although soluble herbage protein is correlated with the occurrence of pasture bloat, we have experienced slow progress in a selection program to reduce soluble-protein concentration in alfalfa. We have found that foam volume is not correlated with …


Evaluation Of Within-Half-Sub Family Selection From Leo Birdsfoot Trefoil, D T. Tomes, O U. Onokpise, B E. Twamley May 2026

Evaluation Of Within-Half-Sub Family Selection From Leo Birdsfoot Trefoil, D T. Tomes, O U. Onokpise, B E. Twamley

IGC Proceedings (1977-2023)

This research was undertaken to evaluate the effectiveness of within-half-sib family recurrent selection for seedling vigor, seed yield, and forage yield in birdsfoot trefoil (Lotus comiculatusL. cv. Leo). The effectiveness of selection was measured by comparing progeny performance, genetic variance, and heritability in selected and unselected populations. In addition, cx­perimc.ntal synthetic• (Syn-2 generation) from the selected population were compared to Leo for forage yield and seed yield in several trials. Seedling vigor and yield in 1979, and forage yield in 1980, of polycross progeny in the selected population were significantly higher than those of similar progeny in the unselected …


Breeding Centrosema Pubescens Better Adapted To Acid Infertile Soils Of South America, E M. Hutton May 2026

Breeding Centrosema Pubescens Better Adapted To Acid Infertile Soils Of South America, E M. Hutton

IGC Proceedings (1977-2023)

Centrosema pubescen, Benth. {centro) in tropical South America depends upon the development of lines with increased tolerance to high acidity and aluminum (Al). This study classified levels of acid tolerance among Centrosema introduc­tions and crosses of promising introductions. Initially, greenhouse and field evaluations in Carimagua oxisol (pH 4.5, 90% Al saturation) were used. Introductions of C. schottii and C. pascuorom died, while most C. virginianum and C. Uutifolium and a few C. pubescens had low acid tolerance. Most C. pubescens introductions had medium acid tolerance, whereas C. macrocarpum and C. schiedanum were highly acid tolerant. The degree of acid …


Comparison Of Italian Ryegrass And Meadow Fescue With F2, F3, F4 Hybrids Of Both Grass Species, H Kaltofen, E Wojahn May 2026

Comparison Of Italian Ryegrass And Meadow Fescue With F2, F3, F4 Hybrids Of Both Grass Species, H Kaltofen, E Wojahn

IGC Proceedings (1977-2023)

In forage-grass breeding there is an increasing interest in hybrids of Italian ryegrass (Lolium multiflorum Lam.) and meadow fescue (Festuca pratensis Huds.). The objective of this study was to investigate some agronomic properties of such Festulolium hybrids with special reference to the question of whether these hybrids change from one generation to the next. In a pot experiment with four levels of nitrogen fertilization, Italian ryegrass and meadow fescue as well as F2, F3, and F4 hybrids of the two grass species were examined for 2 years. In each year four cuts were taken. All the F2, F3, …


Effective Selection For Tolerance To Grass-Killing Herbicides In Perennial Ryegrass (Lolium Perenne L.), C E. Wright, J S. Faulkner May 2026

Effective Selection For Tolerance To Grass-Killing Herbicides In Perennial Ryegrass (Lolium Perenne L.), C E. Wright, J S. Faulkner

IGC Proceedings (1977-2023)

The aim of grassland reseeding is to establish a high-quality sward of improved herbage cultivars. To obtain the maximum value from the improved sward, weed invasion should be prevented. Herbicides are the main tool available. There are many herbicides for selectively controlling dicotyledonous, but not graminaceous, weeds. The control of graminaceous weeds would be possible in swards of grass cultivars selected for tolerance to grass-killing herbicides. Two cycles of recurrent selection for glyphosate tolerance in Lolium perenne L. were carried out by spraying large seedling populations with critical dosages in the greenhouse and intercrossing the survivors. It was found that …


Selection For Specific Leaf Weight In Reed Canarygrass And Its Effects On The Plant, I T. Carlson, D K. Christensen, R B. Pearce May 2026

Selection For Specific Leaf Weight In Reed Canarygrass And Its Effects On The Plant, I T. Carlson, D K. Christensen, R B. Pearce

IGC Proceedings (1977-2023)

Specific leaf weight (SL W, dry weight/unit leaf area) may serve as a selection criterion for forage yield through a positive rela• tionship with photosynthesis. Two cycles of phenotypic selection for high and low SLW were conducted in reed canarygrass (Phalaris anmdinacea L.) to investigate direct and correlated responses, particularly those related to yield and quality of forage. In a space-planted test, average direct responses from two cycles of selection for high and low SLW were 23% and 19%, respectively. Significant correlated responses were obtained for ten traits. Compared with the low-SLW cycle-2 population, the high SLW cycle-2 population averaged …


Value Of White Sweet Lupin In Production Of Protein Fodder And Feeding Of Animals, O Saric, I Ramosevac May 2026

Value Of White Sweet Lupin In Production Of Protein Fodder And Feeding Of Animals, O Saric, I Ramosevac

IGC Proceedings (1977-2023)

The potential of white sweet lupin (Lupinus albus L.) as a grain or forage feed for livestock was investigated in a series of ex­periments. Grain yield of lupin was greater than or equal to that of soybeans (Glycine max [L.] Merrill) in most evaluations. The quality of lupin seed compared favorably with that of soybean meal and fishmeal. Lupin is capable of producing large amounts of forage in a short period, making it a good prospect for forage production in regions that have a short growing season.


Genetic Variability For Morphological And Agronomic Characters In Desmodium Uncinatum (Jacq.) D.C. And D. Intortum (Mill.) Urb., E.M P. Oliveira, P S. Martins, A B. Cruz May 2026

Genetic Variability For Morphological And Agronomic Characters In Desmodium Uncinatum (Jacq.) D.C. And D. Intortum (Mill.) Urb., E.M P. Oliveira, P S. Martins, A B. Cruz

IGC Proceedings (1977-2023)

Objectives of this research were to study the performance of eight populations of D. unicinatum and ten populations of D. intortum, with relation to morphological and agronomic characters to estimate the genetic variation between populations and between plants within populations, and to estimate genetic and phenotypic parameters for these characters.


White Clover: An Olde Crop With A Promising Future, P B. Gibson, W E. Knight, G W. Barnett, W A. Cope, J D. Miller May 2026

White Clover: An Olde Crop With A Promising Future, P B. Gibson, W E. Knight, G W. Barnett, W A. Cope, J D. Miller

IGC Proceedings (1977-2023)

White clover (Trifolium repens L.) is a widely adapted, important forage legume for grazing in the U.S. The palatability and quality of the forage, the wide adaptation of the plants to growth in different climates and under various grazing conditions and the role it plays in supplying nitrogen to pastures make white clover our finest pasture legume. The use of adapted white clover cultivars should result in large economic gains to the livestock industry in the U.S .A. Beef and dairy farmers would profit from reduced need for nitrogen fertilizer, an extended grazing season, increased forage pro­duction and quality, better …


Performance And Variability Of Agronomic Characters In Populations Of Stylosanthes Guianensis (Aubl.) Sw., P S. Martins, N A. Vello May 2026

Performance And Variability Of Agronomic Characters In Populations Of Stylosanthes Guianensis (Aubl.) Sw., P S. Martins, N A. Vello

IGC Proceedings (1977-2023)

Stylosanthes guianens-is (Aubl.) Sw. shows wide variations in morphological and physiological characteristics, and basic infor­mation on genetic variability is needed for future breeding programs. The objectives of this paper were to evaluate 25 native Brazilian populations of S. guianensis for forage characteristics · • ;10,d • to estimate genetic and phenotypic parameters for these characters. The experiment was conducted in a duplicated 5 x 5 balanced lattice design with plots that contained 4 individuals spaced on 2-m centers. The following characters were evaluated after the beginning of flowering period: days to flowering (DF), mean diameter (MD), basal area (BA), growth …


Rhizoma Peanut: Perennial Warm-Season Forage Legume, G M. Prine May 2026

Rhizoma Peanut: Perennial Warm-Season Forage Legume, G M. Prine

IGC Proceedings (1977-2023)

Rhizoma peanut is the common name given species in section Rhizomatosae of the genus Arachis. Florigraze rhizoma peanut (A. glabrata Benth.) has been released as a cultivar by the Florida agricultural experiment stations and the USDA Soil Conserva­tion Service. Florigraze is adapted to the well-drained soils of Florida and the warm humid tropics and subtropics around the world. Rhizoma peanuts are propagated by rhizomes, which in Florida are best planted during winter. The slowness of coverage during early establishment is the biggest shortcoming of rhizoma peanuts. If they are established first, rhizoma peanuts will grow well in mixture with bermudagrass …


Hedysarum Mongolicum Turcz.: An Important Protein Resource Legume On Dry Sandy Land, Li Min, A W. Hovin May 2026

Hedysarum Mongolicum Turcz.: An Important Protein Resource Legume On Dry Sandy Land, Li Min, A W. Hovin

IGC Proceedings (1977-2023)

In searching for plants that can both increase the protein production and improve the sandy-soil conservation of the grassland in the arid, windy regions of North China, so far, from among many native plants, we have identified Hedysarum mongolicum Turcz. as the best species to fulfill our dual purposes. We investigated its distribution, planted its native seeds in the Maowusu desert, and studied it under its native and cultivated growing conditions from 1957 to 1964. Chinese farmers call this perennial subbrush legume of the sweetvetcb genus "Yang Cai," meaning "sheep like to eat." It can thrive in the stable or …


Adaptation And Utilization Of Three Legume In China, Huang Wenhui May 2026

Adaptation And Utilization Of Three Legume In China, Huang Wenhui

IGC Proceedings (1977-2023)

China is a vast territory with extremely varied climates, soil, and topography, and it is very rich in pasture grass resources. The main legumes for forage are Alfalfa (Medicago sativa L.), yellow alfalfa (Medicago folcata L.) and shadawang (Astragalis adsurgent Pall.)


Preliminary Evaluation Of Legume Germ Plasm In The Cerrados Of Brazil, D Thomas, R P. De Andrade May 2026

Preliminary Evaluation Of Legume Germ Plasm In The Cerrados Of Brazil, D Thomas, R P. De Andrade

IGC Proceedings (1977-2023)

In 1978 an evaluation program was initiated to select legumes that (1) grow and produce seed on acid soils under aluminum and water stress, (2) persist under grazing, and (3) tolerate pests and diseases. The work is being conducted at the Cerrados Agricultural Research Center, near Brasilia, at lat 15°S and altitude 1,000 to 1, 100 m . Annual rainfall is 1,500 mm, mostly distributed in a 6-month wet season, and mean annual temperature is 21°C. Nine hundred legume accessions from thirteen genera have now been established as spaced plants on the 2 major soil types of the region. The …


Genetics And Utilization Of Apomixis For The Improvement Of Guineagrass (Panicum Maximum Jacq.), Y H. Savidan May 2026

Genetics And Utilization Of Apomixis For The Improvement Of Guineagrass (Panicum Maximum Jacq.), Y H. Savidan

IGC Proceedings (1977-2023)

Natural polymorphism in guineagrass (Panicum maximumjacq.) has been stabilized in tetraploid biotypes by apomixis. Sex­ual diploids were found in East African populations. Our objective was to determine whether apomixis could be related with a simple genetic background and manipulated in an improvement program. Apomicts of guineagrass are characterized by a 4-nucleate embryo sac structure, and this trait was used in genetical analyses to differentiate apomictic from sexual hybrids. Progeny tests were also conducted as controls. Ten different types of progenies were analyzed: tetraploid sexual (from colchicine treatment of diploids) x apomictic F1 hybrids; selfed and backcrossed progenies of sexual F1 …


Breeding Challenges In Apomictic Warm-Season Grasses, E C. Bashaw, P W. Voigt, B L. Burson May 2026

Breeding Challenges In Apomictic Warm-Season Grasses, E C. Bashaw, P W. Voigt, B L. Burson

IGC Proceedings (1977-2023)

Efforts to breed apomictic grasses met with little success in the past, but results of more recent research show significant progress with some species and new prospects for improving apomicts. Early research uncovered the cytological basis for apospory and diplospory, found the common apomictic mechanisms in grasses, and showed that apomixis is transmitted from pannt to offspring. Discovery of sexual or partially sexual (facultative apomicts) plants in several species formerly considered obligate apomicts allowed for hybridization and genetic studies. Results of subsequent research confirmed inheritance of apomixis, and data from the more conclusive studies indicate that method of reproduction …


Extra Omnes: Analyzing The United States’ And Ireland’S Methods Of Quelling The Criminal Clergy Sexual Abuse Scourge, Dana Aprigliano May 2026

Extra Omnes: Analyzing The United States’ And Ireland’S Methods Of Quelling The Criminal Clergy Sexual Abuse Scourge, Dana Aprigliano

Journal of Catholic Legal Studies

(Excerpt)

In late 2008, an Irish businessman was successful in legally preventing sexual assault claims from being brought against him. In explaining why one “victim” should be discredited, the court cited a threat she made against the businessman to make allegations of a sexual nature against him if he did not pay her a sum of money. In particular, she told him that if he did not pay her, she would “have him . . . ’plastered all over the front of the Evening Herald like those p[e]dophile priests.’ ” Although the businessman was not a priest or, as it …


An Underrecognized Mechanism Of Spontaneous Pneumomediastinum: The Macklin Effect Following Valsalva Maneuvers, Ripudaman Singh, Fatimah Bello May 2026

An Underrecognized Mechanism Of Spontaneous Pneumomediastinum: The Macklin Effect Following Valsalva Maneuvers, Ripudaman Singh, Fatimah Bello

Research Symposium

Background: Spontaneous pneumomediastinum (SPM) is a rare clinical condition characterized by the presence of free air in the mediastinum without preceding trauma, surgery, or invasive procedures. It predominantly affects young adults and commonly presents with acute retrosternal chest pain that is pleuritic in nature and may radiate to the neck, shoulders, or arms. Although often idiopathic, SPM is associated with conditions that increase intra-alveolar pressure, including asthma exacerbations, respiratory infections, forceful coughing or vomiting, and less commonly, Valsalva maneuvers related to intense physical activity. We report a case of uncomplicated SPM in a previously healthy young adult associated with Valsalva …


The Role Of Artificial Intelligence In Marine Pollution: A Review, Safaa A. Abdel Ghani, Sahar W. M. Hassan, Aida H. Shobier May 2026

The Role Of Artificial Intelligence In Marine Pollution: A Review, Safaa A. Abdel Ghani, Sahar W. M. Hassan, Aida H. Shobier

Blue Economy

Marine pollution represents a significant threat to the sustainable use of ocean resources and is increasing globally. Consequently, multidimensional and sustainable ocean governance frameworks have placed growing emphasis on the prevention, reduction, and elimination of marine pollution. In recent years, artificial intelligence (AI) has been increasingly adopted as an effective tool for monitoring, assessing, and managing marine pollution. This review aimed to highlight the role of artificial intelligence in addressing marine pollution. The efforts of scientists in employing and leveraging the advantages of AI to tackle the issue of marine pollution were examined. It was found that AI, supported by …


Virtual Workplace And Employee Engagement, Victoria Cox, Alisa Allen May 2026

Virtual Workplace And Employee Engagement, Victoria Cox, Alisa Allen

Journal of Fundamental & Applied Business Research

This article examined virtual workplace employees and employee engagement challenges and solutions. Employees who work remotely often feel disconnected from coworkers, organizational missions, and have a feeling of emotional isolation. This article examined the problems organizations face when not prioritizing virtual socialization for remote workers, leading to employee turnover, disengagement, and loneliness. The systematic review consisted of conducting a review within the Liberty University Jerry Falwell Library, encompassing empirical studies sourced from ProQuest, EBSCO, Emerald, and Gale databases. Studies published in peer reviewed journals, and the BibleGateway online between 2021 and 2026. A total of 33 journals were synthesized to …


Equity's Bruen Moment: Trump V. Casa And Lessons For The Future Of History And Tradition, Jacob D. Charles May 2026

Equity's Bruen Moment: Trump V. Casa And Lessons For The Future Of History And Tradition, Jacob D. Charles

Florida Law Review

In Trump v. CASA, the Supreme Court expounded on and applied a methodological framework that mimics the test the Court has recently begun deploying in Second Amendment and other individual rights cases. That test has three primary components: (1) search for historical analogues; (2) apply historical principles; and (3) abjure contemporary concerns that can be labeled “policy” considerations. Bruen’s echoes in CASA are noticeable and telling. So too are the lessons that CASA can teach about how the Court’s approach to history and tradition is continuing to develop.

This Article analyzes CASA as a window into the Court’s …


Book Reviews, Paul Flowers, Madel Jacobs Morgan May 2026

Book Reviews, Paul Flowers, Madel Jacobs Morgan

Journal of Mississippi History

No abstract provided.


Abiraterone-Induced Resistant Hypokalemia And Hypertension: A Preventable Complication, Ripudaman Singh, Seokwon Choi, Aramide Tijani, Fatimah Bello May 2026

Abiraterone-Induced Resistant Hypokalemia And Hypertension: A Preventable Complication, Ripudaman Singh, Seokwon Choi, Aramide Tijani, Fatimah Bello

Research Symposium

Background: Abiraterone, a cytochrome P17 (17a-hydroxylase/C17,20-lyase) inhibitor used in metastatic castration-resistant prostate cancer (CRPC), suppresses androgen and cortisol synthesis, leading to elevated ACTH and accumulation of mineralocorticoid precursors such as 11-deoxycorticosterone and corticosterone, both possessing potent mineralocorticoid activity1,2,3. Concomitant prednisone is recommended to prevent this cascade, as its omission can lead to clinically significant mineralocorticoid excess manifesting as severe hypokalemia, hypertension, and fluid retention4. This preventable complication remains underrecognized, particularly in elderly patients who are frequently exposed to polypharmacy. Here, we report a patient with metastatic CRPC on abiraterone therapy who presented with acute wrist pain, …


Severe Ldl-C Elevation With Negative Monogenic Familial Hypercholesterolemia Testing: A Case Of Polygenic Hypercholesterolemia, Ripudaman Singh, Daniela Hernandez May 2026

Severe Ldl-C Elevation With Negative Monogenic Familial Hypercholesterolemia Testing: A Case Of Polygenic Hypercholesterolemia, Ripudaman Singh, Daniela Hernandez

Research Symposium

Background: Severe hypercholesterolemia, defined as a low-density lipoprotein cholesterol (LDL-C) level ≥190 mg/dL, is most often attributed to familial hypercholesterolemia (FH), a monogenic autosomal dominant disorder caused by pathogenic variants in genes essential for LDL-C catabolism, including the low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), proprotein convertase subtilisin/kexin type 9 (PCSK9), and LDL receptor adaptor protein 1 (LDLRAP1). Clinically, FH is characterized by markedly elevated LDL-C levels and an increased risk of premature atherosclerotic cardiovascular disease (ASCVD). Homozygous individuals typically present in childhood, while heterozygous individuals are more commonly diagnosed in adulthood. However, a substantial proportion of patients with an …