Digital Commons Network^™

Synthesis And Characterization Of Polymeric Nanoparticles To Enhance Celleullar Drug Delivery, Rahma Aly

Chemistry Theses

Medicines in the form of nanoparticles called nanomedicines, stand at the forefront of revolutionary advancements in healthcare, offering precise drug delivery and diagnostic capabilities. A recent example of nanomedicine in the clinic is the COVID-19 vaccine, which helped prevent death during the pandemic. While the potential benefits are immense, a myriad of challenges complicate their seamless integration into clinical practice. The design and fabrication of nanoparticles demand meticulous attention to biocompatibility and toxicity. Interactions with biological systems are complex, requiring a delicate balance between therapeutic efficacy and safety. The reticuloendothelial system's rapid clearance of nanoparticles, their instability in physiological environments, …

Rethinking Legislative Facts, Haley N. Proctor

Notre Dame Law Review

As the factual nature of legal inquiry has become increasingly apparent over the past century, courts and commentators have fallen into the habit of labeling the facts behind the law “legislative facts.” Loosely, legislative facts are general facts courts rely upon to formulate law or policy, but that definition is as contested as it is vague. Most agree that legislative facts exist in some form or another, but few agree on what that form is, on who should find them, and how. This Article seeks to account for and resolve that confusion. Theories of legislative fact focus on the role …

Intellectual Property And The Myth Of Nonrivalry, James Y. Stern

Notre Dame Law Review

The concept of rivalry is central to modern accounts of property. When one per-son’s use of a resource is incompatible with another’s, a system of rights to determine its use may be necessary. It is commonly asserted, however, that informational goods like inventions and expressive works are nonrivalrous and that intellectual property rights must therefore be subject to special limitation, if they should even exist at all. This Article examines the idea of rivalry more closely and makes a series of claims about the analysis of rivalrousness for purposes of such arguments. Within that frame-work, it argues that rivalry should …

Who Is A Minister? Originalist Deference Expands The Ministerial Exception, Jared C. Huber

Notre Dame Law Review

The ministerial exception is a doctrine born out of the Religion Clauses of the First Amendment that shields many religious institutions’ employment decisions from review. While the ministerial exception does not extend to all employment decisions by, or employees of, religious institutions, it does confer broad—and absolute—protection. While less controversy surrounds whether the Constitution shields religious institutions’ employment decisions to at least some extent, much more debate surrounds the exception’s scope, and perhaps most critically, which employees fall under it. In other words, who is a "minister" for purposes of the ministerial exception?

Imsaloquium 2024 Event Booklet, Student Inquiry And Research (Sir)

IMSAloquium Event Booklets

Cover design by Harish Chandar '26

Welcome to IMSAloquium 2024. This is IMSA’s 37th year of leading in educational innovation, and the 36th year of the IMSA Student Inquiry and Research (SIR) Program.

Detection Of Endocrine-Disrupting Chemicals In Personal Care Products Using A Polyhedral Oligomeric Silsesquioxane-Based Hybrid Material, Aarthi K

Theses and Dissertations

Personal care products (cosmetics) are a diverse group of goods, that includes all the essential routines including the personal hygiene products used in our day-to-day life. It contains a variety of ingredients in its formulation, including preservatives, flavor, UV filters, and other additives. Few of the chemicals utilized are found to impair human health and have serious environmental impacts. The major chemicals include parabens, triclosan, oxybenzone, phthalates, heavy metals, fragrances, etc, Though the Scientific Committee on Consumer Safety (SCCS) has set the usage limits for the chemicals used, exposure to these chemicals from multiple products may exceed the exposure limit. …

An Exploration Of The Effectiveness Of Xanthorrhiza Simplicissima And Its Secondary Alkaloids As Antibiotics Against Staphylococcus Aureus With The Use Of Reserpine, Donald Bothe, Savita Chaurasia

Undergraduate Theses

Xanthorhiza simplicissima is a plant that is steeped in medical history. It has been used for hundreds of years by the Native Americans, and later by the Europeans, of Appalachia for its medicinal properties. One of the most useful medical applications of this plant are its antibiotic properties, as typified by its use as a tea that was consumed to treat mouth sores. These antibiotic properties can be attributed to some of its secondary alkaloids such as berberine, liriodenine, oxyacanthine, and magnoflorine. These compounds have been studied in other systems; however, oxyacanthine and magnoflorine have not been researched in tandem …

Acetaminophen Influences Musculoskeletal Signaling But Not Adaptations To Endurance Exercise Training, Brandon Roberts, Alyssa Geddis, Alexandra Ciuciu, Marinaliz Reynoso, Nikhil Mehta, Alyssa Varanoske, Alyssa Kelley, Raymond Walker, Rigoberto Munoz, Alexander Kolb, Jeffery Staab, Marshall Naimo, Ryan Tomlinson

Department of Orthopaedic Surgery Faculty Papers

Acetaminophen (ACE) is a widely used analgesic and antipyretic drug with various applications, from pain relief to fever reduction. Recent studies have reported equivocal effects of habitual ACE intake on exercise performance, muscle growth, and risks to bone health. Thus, this study aimed to assess the impact of a 6-week, low-dose ACE regimen on muscle and bone adaptations in exercising and non-exercising rats. Nine-week-old Wistar rats (n = 40) were randomized to an exercise or control (no exercise) condition with ACE or without (placebo). For the exercise condition, rats ran 5 days per week for 6 weeks at a 5% …

New University Architect Contributes To 1,000 Projects And Counting, Erin Garrett

University of Mississippi News

OXFORD, Miss. – Some of Chad Hunter's fondest memories of childhood involve sitting at a table with his grandfather and drawing. Not drawing as one typically does as a kid, but drawing house and building plans.

The Daily Gamecock: April 2024, University Of South Carolina, Office Of Student Media

April

No abstract provided.

Implementing Directed Security Rounding With The Brøset Violence Checklist: A Quality Improvement Project, Jacqueline Ortiz

DNP Projects

Significance and Background: Violence against healthcare workers is an international issue. The rates of workplace violence (WPV) have been steadily increasing over the last few years. The practice setting implemented the use of the Brøset Violence Checklist (BVC) system-wide in July 2022, following the Joint Commission’s new standards for WPV prevention. The BVC is a checklist of six behaviors (confusion, irritability, boisterousness, physical threats, verbal threats, and attacking objects) that the nurses score as a 1 (present) or 0 (absent), and the higher the sum of the scores the greater the risk of violence. A score of three or greater …

On Learning Your Gender: A Comprehensive View, Audra M. Hazelwood

Theses

This essay provides a metaphysical and epistemological account of gender. The metaphysics involves a ‘non-reductionist view of gender’, which is to say that gender cannot be reduced to a single factor. On this view gender begins with one’s innate gender inclinations (in the vein of Julia Serano). These inclinations pick out a specific range of gender possibilities from the gender spectrum that apply to a person. At the same time we live in communities and cultures with certain gender norms. This is where epistemology comes into play since our gender inclinations are filtered through gender norms and some people are …

A Reputation System For Provably-Robust Decision Making In Iot Blockchain Networks, Charles C. Rawlins, Sarangapani Jagannathan, Venkata Sriram Siddhardh Nadendla

Electrical and Computer Engineering Faculty Research & Creative Works

Blockchain systems have been successful in discerning truthful information from interagent interaction amidst possible attackers or conflicts, which is crucial for the completion of nontrivial tasks in distributed networking. However, the state-of-the-art blockchain protocols are limited to resource-rich applications where reliably connected nodes within the network are equipped with significant computing power to run lottery-based proof-of-work (pow) consensus. The purpose of this work is to address these challenges for implementation in a severely resource-constrained distributed network with internet of things (iot) devices. The contribution of this work is a novel lightweight alternative, called weight-based reputation (wbr) scheme, to classify new …

2024 Forces, Collin College

Forces

No abstract provided.

The Grandchildren And The Memories, Viona A. Diorga

Forces

No abstract provided.

Professional Development Strategies For Treating People With Idd And Mental Health Needs, Jennifer L. Mclaren, Elizabeth Grosso, Karen L. Weigle

Faculty Publications

People with intellectual and developmental disabilities (IDD) experience significant health and mental health inequities and difficulties accessing care. There are few initiatives that train mental health professionals to care and advocate for the health and mental health care needs of people with intellectual and developmental disabilities.

Development Of A Discrete Element Model For Artificial Turf, Justin Rittenhouse

Dissertations

NFL data exhibits a distinct correlation between an elevated lower extremity injury rate and synthetic surfaces. These ubiquitous injuries frequently relate to excessive foot traction (i.e., failure to release causing fracture or soft tissue damage). Consequently, a discrete element model was developed using open-source software to analyze stud traction. First, laboratory data was collected via bench level experiments covering seventeen different testing scenarios. A minimum of twenty-five samples were collected per scenario. Total work, average torque, and maximum torque were used as indicators of stud grip. And the latter two were statistically analyzed for outliers and significant differences. Next, an …

Quantum Search Algorithms For Constraint Satisfaction And Optimization Problems Using Grover's Search And Quantum Walk Algorithms With Advanced Oracle Design, Abdirahman Sheikh Hassan Alasow

Dissertations and Theses

The field of quantum computing has emerged as a powerful tool for solving and optimizing combinatorial optimization problems. To solve many real-world problems with many variables and possible solutions for constraint satisfaction and optimization problems, the required number of qubits of scalable hardware for quantum computing is the bottleneck in the current generation of quantum computers. In this dissertation, we will demonstrate advanced, scalable building blocks for the quantum search algorithms that have been implemented in Grover's search algorithm and the quantum walk algorithm. The scalable building blocks are used to reduce the required number of qubits in the design. …

Cas Connections- 2024 Spring Term - April, Dean's Office College Of Arts And Science

CAS Connections

No abstract provided.

General Non-Destructive Evaluation For Friction Stir Welding, Johnathon Bryce Hunt

Theses and Dissertations

Friction stir welding (FSW) is an advantageous solid state joining method for many different engineering designs. It was invented in 1991 by TWI and since that time a tremendous amount of research has been executed to understand and implement FSW in a myriad of materials in numerous industries such as aerospace, ship building, train, automotive, energy, agriculture and others. Most industries have strict weld inspection processes to validate a weld before it is put into service. One of the main weld characteristics that is measured is the size of any subsurface volumetric voids. The current standard to test friction stir …

Community-Level Post-Hazard Functionality Methodology For Buildings Exposed To Floods, Omar Nofal, Nathanael Rosenheim, Sabarethinam Kameshwar, Jayant Patil, Xiangnan Zhou, John W. Van De Lindt, Leonardo Duenas-Osorio, Eun Jeong Cha, Amin Endrami, Elaina Sutley, Harvey Cutler, Tao Lu, Chen Wang, Hwayoung Jeon

Faculty Publications

This paper presents a building-level post-hazard functionality model for communities exposed to flood hazards including the interdependencies between the population, buildings, and infrastructure. An existing portfolio of building archetypes is used to model the post-hazard physical flood functionality of different building typologies within the community with the goal of supporting resilience-informed decision-making. Specific fragility-based flood functionality curves were developed for this portfolio to quantify the exceedance probability of a prescribed set of functionality states. While the physical functionality of buildings is significant to the total functionality of a building and community resilience assessment, the functionality of utilities such as power …

Unh’S Easton White Named To Un’S World Ocean Assessment Working Group, Nicholas Gosling

UNH Today Archive

No abstract provided.

04.15.2024 Orsp Connect, Liz Williamson

ORED Newsletter

DMP Tool, Jeff Neal, new training module: Budget Basics, new policy Maligned Foreign Talent Recruitment

A Dnp Project: Improving Clinical Alarm Management Through An Alarm Management Bundle: A Quality Improvement Project, Mary I. Alejo

Doctor of Nursing Practice Final Project Abstract

The purpose is to increase nurses' perception toward clinical alarm management by implementing an alarm management bundle and educational skills in a Cardiovascular Intensive Care Unit (CVICU). The project was implemented in a 31- bed CVICU at a teaching facility in the Texas Medical Center. The Plan-Do-Study-Act was the chosen quality improvement model for the DNP project. Paper-based surveys were used to assess baseline data on competency and confidence levels of alarm management on the Philips monitor with the Healthcare Technology Foundation (HTF) Survey and the Nurse Competence on Philips Physiologic Monitors Use Survey. Active rounds were conducted to ensure …

Enhancing Library And Information Centres: Efficient Methods For Texts And Images Recognition In Digital Era, Oladotun Ayowumi Osunkentan, Peace Caleb Morakinyo

Library Philosophy and Practice (e-journal)

This study explores the latest advancements in efficient text and image recognition methods, highlighting their significance and potential applications in libraries and information centers. This study delve into cutting-edge technologies, such as deep learning and computer vision, which have revolutionized how text and images are recognized and interpreted. In the ever-evolving digital landscape, the need for efficient methods for text and image recognition has become paramount. With the proliferation of digital content across various platforms and the exponential growth of data, the ability to accurately and rapidly identify, process, and understand text and images has significant implications for numerous fields, …

The Echo: April 15, 2024, Taylor University

2023-2024 (Volume 111)

No abstract provided.

An Exploration Of Pediatric Occupational Therapist's Perspectives On Functional And Assistive Mobility, Jennifer Allison, Amy Lyons-Brown

Spring 2024 Virtual OTD Capstone Symposium

Background: Occupational therapists (OTs) are highly skilled in assessing context, environment, and sensory-motor needs which are critical in addressing functional mobility and implementing assistive mobility devices. There is limited research on pediatric OT’s role in functional mobility. This study aims to explore pediatric OT's roles and perceptions of functional mobility and the implementation and use of assistive mobility devices.

Methods: Data was collected via an online survey with an option to participate in a follow-up interview. Descriptive statistics and thematic analysis were used to summarize trends and differences in the data.

Results: Twenty licensed OTs working in a variety of …

A Republic Of Pawprints: The Rise And Reign Of The Alaskan Sled Dog, 1870-1970, Christopher David Adkins

USF Tampa Graduate Theses and Dissertations

This dissertation charts the career of the Alaskan sled dog: how it was used as an engine of development, how it became a symbol for early American Alaska, and how it fell victim to obsolescence as newer and faster means of conveyance became available. The figure of the sled dog in the Arctic is complex. Because it was closer to the wolf in phenotype both it, and Alaska, were buffeted by the same White settler expectations and Darwinian chauvinism which afflicted its Indigenous peoples. This would intensify during the baptisms by fire of the gold rushes. Dog abuse – overwork, …

Research On Cross-Domain Unmanned Swarm Cooperative Anti-Submarine Search Method, Ning Wang, Xiaolong Liang, Jiaqiang Zhang, Yueqi Hou, Aiwu Yang

Journal of System Simulation

Abstract: For the maritime ASW search, a cross-domain unmanned swarm cooperative search method is proposed in which USVs are used as the communication relay of UAVs. The digital grid map is used to characterize the mission area and the kinematic model of cross-domain platform is constructed. The cooperative method of cross-domain unmanned systems is proposed, and the distributed information fusion mechanism of unmanned systems is designed. The search objective function for heterogeneous platforms is designed to guide the unmanned systems to make real-time decisions in search task. The simulation results show that the proposed method can be effective to the …

Simulation Verification And Decision-Making Key Technologies Of Unmanned Swarm Game Confrontation: A Survey, Xiaolong Liang, Aiwu Yang, Jiaqiang Zhang, Yueqi Hou, Ning Wang, Xiao Huang, Junbin Gong

Journal of System Simulation

Abstract: Unmanned swarm game confrontation is a new combat mode and plays a crucial role in intelligent warfare. Its core is the autonomous generation of a series of game confrontation decision sequences to "empower" the swarm. The progress of system simulation verification for the unmanned swarm game confrontation is analyzed. The key technologies of the autonomous decision-making are discussed from three aspects, technology based on expert systems and game theory, technology based on swarm intelligence and optimization theory, and technology based on neural networks and reinforcement learning. The key technology research conducted by the author's team on the autonomous decisionmaking …