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Topical Gels For Cromolyn Sodium Delivery In Atopic Dermatitis: Unveiling The Potential Of Sodium Salts Of Fatty Acids As Permeation Enhancers, Adela Adu Agyemang, Alanis Vang, Akeemat Tijani, Ashana Puri Apr 2024

Topical Gels For Cromolyn Sodium Delivery In Atopic Dermatitis: Unveiling The Potential Of Sodium Salts Of Fatty Acids As Permeation Enhancers, Adela Adu Agyemang, Alanis Vang, Akeemat Tijani, Ashana Puri

Appalachian Student Research Forum

Atopic dermatitis, commonly known as eczema, is a chronic inflammatory disorder caused by an overactive immune system. Atopic dermatitis usually develops in early childhood and is prevalent in people with family history of eczema. Several studies have suggested the use of cromolyn sodium (CS), a mast cell stabilizer, as an effective therapeutic agent for treating atopic dermatitis. This study explored the effect of the use of sodium caprylate and sodium oleate as enhancers on topical delivery of CS from a gel-based formulation. An extemporaneously prepared formulation called the Magic Masto Lotion, MML (0.3% CS), has been making waves in terms …


Prevalence And Risk Factors Of Obesity In Tennessee And Non-Tennessee, Using The Behavior Risk Factor Surveillance System Data From 2014-2022, Nikita Cudjoe, Yan Cao, Sheryl Strasser, Shimin Zheng Apr 2024

Prevalence And Risk Factors Of Obesity In Tennessee And Non-Tennessee, Using The Behavior Risk Factor Surveillance System Data From 2014-2022, Nikita Cudjoe, Yan Cao, Sheryl Strasser, Shimin Zheng

Appalachian Student Research Forum

Overweight and obesity, categorized by the World Health Organization (WHO) as Body Mass Index (BMI) ≥ 25 and ≥ 30 kg/m², respectively, pose substantial threats to both individual health and societal welfare. They elevate the likelihood of chronic ailments like cardiovascular diseases, Type 2 diabetes, and various cancers. Tennessee, mirroring many other U.S. states, grapples with pronounced challenges concerning overweight and obesity, as evidenced by escalating prevalence rates documented by the Centers for Disease Control and Prevention (CDC). This study seeks to discern risk factors by comparing Behavioral Risk Factor Surveillance System (BFRSS) data from Tennessee with data from non-Tennessee …


Investigating Perceptions Of Health In The U.S: The Interplay Of Religion And Sociodemographic Characteristics, Tolulope Adeusi, Kelly Foster Apr 2024

Investigating Perceptions Of Health In The U.S: The Interplay Of Religion And Sociodemographic Characteristics, Tolulope Adeusi, Kelly Foster

Appalachian Student Research Forum

Despite advances in healthcare, health disparities remain globally. This study investigates the complex relationship between religion, income, age, race, and overall health. In particular, I investigated how religious affiliation and practices affect perceptions of overall health while controlling for socio-demographic and economic factors such as gender, race, and income. This study contributes to a better understanding of the multifaceted determinants of health. Existing literature suggests a nuanced interplay between religion and/or spirituality, socio-demographic characteristics, and various health outcomes (Koenig et al., 2013). While some studies highlight the positive contributions of religion and spirituality to mental and/or physical health (Roger & …


The Effects Of Childhood Emotional Maltreatment On Adulthood Relationships Of Minority Women: A Qualitative Study, Suzanne Aguirre, Christine Browning Apr 2024

The Effects Of Childhood Emotional Maltreatment On Adulthood Relationships Of Minority Women: A Qualitative Study, Suzanne Aguirre, Christine Browning

Appalachian Student Research Forum

Childhood Emotional Maltreatment (CEM) , which encompasses both childhood abuse and childhood neglect, exerts various adverse effects on brain development and response to diverse situations, particularly in relationships. Drawing from Bowlby’s attachment theory, this study investigated how relationships may be jeopardized for individuals who endured maltreatment in childhood. The aim of this study is to assess the effect of CEM on adulthood relationships, specifically parental and romantic relationships. Through interviews, we explored the emotion regulation and attachment patterns of four racial/ethnic minority women aged 20 to 27 in Appalachia––all of whom experienced emotional maltreatment during childhood––to discern the roles these …


Exploring The Dynamics Of Depression, Sleep Deprivation, And Self-Esteem: An In-Depth Advanced Statistical Analysis, Muslihat Gaffari, Mostafa Zahed Apr 2024

Exploring The Dynamics Of Depression, Sleep Deprivation, And Self-Esteem: An In-Depth Advanced Statistical Analysis, Muslihat Gaffari, Mostafa Zahed

Appalachian Student Research Forum

Depression, characterized by persistent feelings of sadness and loss of interest or pleasure in activities, is a pervasive mental health disorder affecting millions worldwide. Sleep deprivation, often intertwined with depression, exacerbates its symptoms, and contributes to a vicious cycle of emotional distress and cognitive impairment. Additionally, self-esteem, the subjective evaluation of one's worth and capabilities, plays a crucial role in shaping individuals' mental well-being and resilience against psychological challenges. Understanding how these factors intersect and influence each other is essential for developing targeted interventions and support systems. Understanding the complex interactions between depression, sleep deprivation, and self-esteem is paramount for …


Dried Saliva Spot As An Effective Tool In The Diagnosis And Management Of Chronic Disease., Naveen Chaurasia, Ankit Jain, Nitin Dubey Apr 2024

Dried Saliva Spot As An Effective Tool In The Diagnosis And Management Of Chronic Disease., Naveen Chaurasia, Ankit Jain, Nitin Dubey

The Thai Journal of Pharmaceutical Sciences

In recent decades, there has been significant progress in non-invasive sampling techniques, which serve as effective tools in treating and managing various chronic diseases. Among these techniques, dried saliva spot (DSS) sampling of human saliva has emerged as a prominent alternative to serum for detecting targeted molecules. The diagnostic potential of saliva has been extensively studied, highlighting its applicability across a spectrum of diseases. In addition to DSS, other sampling methods, such as dried plasma spots, dried blood spots, and dried matrix spots, have been explored. Various types of filter papers have been employed in DSS sampling procedures, with notable …


Skin Irritation Of Capsicum Patches By In Vitro Study And Human Repeated Insult Patch Test., Apirada Sucontphunt, Tun Chusut, Thaniya Wannakup, Paninee Chetprayoon, Laksana Charoenchai Apr 2024

Skin Irritation Of Capsicum Patches By In Vitro Study And Human Repeated Insult Patch Test., Apirada Sucontphunt, Tun Chusut, Thaniya Wannakup, Paninee Chetprayoon, Laksana Charoenchai

The Thai Journal of Pharmaceutical Sciences

The use of capsaicin, a natural active compound for pain management, in various health products has continuously increased. Capsaicin has been shown to suppress pain by decreasing substance P; however, the safety information of capsaicin formulations requires support from numerous studies. For that reason, in this research, the skin irritancy of a capsaicin hydrogel transdermal patch was evaluated and compared to that of a commercial relief patch by in-vitro skin irritation and a human repeated insult patch test (HRIPT). In-vitro skin irritation of samples was performed using reconstructed human epidermis. The percentage of tissue viability was evaluated and compared. For …


Additional Control Data Path Into Legacy Pluggable Form Factors, Brandon Dusek, Aj Velarde, Latha Sathappan, Hailing Wang Apr 2024

Additional Control Data Path Into Legacy Pluggable Form Factors, Brandon Dusek, Aj Velarde, Latha Sathappan, Hailing Wang

Defensive Publications Series

Techniques are presented herein that support an additional control data path for a pluggable module that employs the module’s Vcc power pins. Adding a signal modulation path to a pluggable module’s Vcc power delivery and then using the same as a management communication interface provides a form-factor agnostic approach to expand a module’s management channel. Such a data path can operate in addition to the Inter-Integrated Circuit (I2C) interface communication lines to support the sending of larger amounts of data at cumulatively faster speeds. Additionally, the presented techniques provide an approach to backward compatibility that will be tolerable by older …


Dating Apps As An Outlet To Promote Sexual Autonomy Among Disabled Individuals: An Intersectional Approach To Change, Sarah Marrs Apr 2024

Dating Apps As An Outlet To Promote Sexual Autonomy Among Disabled Individuals: An Intersectional Approach To Change, Sarah Marrs

Sexual Ethics

As disabled individuals are forced into the social other and an asexual narrative, dating apps provide an outlet for this demographic to engage in their sexuality in a format that is more easily accessible. In an age of rising technology, the destigmatization and usage of dating apps highlights the self-expressive potential of an underrepresented and misunderstood demographic. This issue is addressed through historical perspectives of “crip sex,” a comparison between the disabled dating experience and the able-bodied dating experience, and a description of the significance of a dating app designed for individuals with disabilities.


Ben Bufford Manuscripts, Arkansas State University - Jonesboro Apr 2024

Ben Bufford Manuscripts, Arkansas State University - Jonesboro

Archival Collection Finding Aids

Ben Bufford was an English teacher at Jonesboro High School in Arkansas and Madera High School in California who wrote numerous poems. He also wrote manuscripts for several short stories and novels. This collection consists of manuscripts of the various literary works of Ben Bufford.


Exploring Attitudes Toward Pre-Exposure Prophylaxis For Hiv Prevention Prior To Implementation Among Female Sex Workers In Malaysia: Results From A Qualitative Study, Shaylen Foley, Danya E. Keene, Roman Shrestha, Shan-Estelle Brown, Kamal Gautam, Ryan A. Sutherland, Francesca Maviglia, Rumana Saifi, Jeffrey A. Wickersham Apr 2024

Exploring Attitudes Toward Pre-Exposure Prophylaxis For Hiv Prevention Prior To Implementation Among Female Sex Workers In Malaysia: Results From A Qualitative Study, Shaylen Foley, Danya E. Keene, Roman Shrestha, Shan-Estelle Brown, Kamal Gautam, Ryan A. Sutherland, Francesca Maviglia, Rumana Saifi, Jeffrey A. Wickersham

Faculty Publications

No abstract provided.


A Qualitative Case Study Of An Ultra-Brief Trait Emotional Intelligence Intervention For University Student Leaders, Britne K. Bacca-Haupt, Melinda R. Dilley, Fletcher J. Ferguson, Lisa C. Gillis-Davis, Jacqueline M. Schneller Apr 2024

A Qualitative Case Study Of An Ultra-Brief Trait Emotional Intelligence Intervention For University Student Leaders, Britne K. Bacca-Haupt, Melinda R. Dilley, Fletcher J. Ferguson, Lisa C. Gillis-Davis, Jacqueline M. Schneller

Dissertations

Emotional intelligence gained interest in the early 1990s from researchers in hopes of assessing how understanding and developing emotions can help individuals be “healthy, rich, successful, loved, and happy” (Mayer et al., 2001, p. xi). Because of the expanded interest, increasing implications began occurring at the postsecondary level of education (Petrides et al., 2018). Trait emotional intelligence focuses on perceptions of oneself and others, illustrating how we regulate our emotions and recognize them in others. This qualitative study aimed to explore the impact of an ultra-brief intervention on the trait emotional intelligence development of university student leaders and how they …


Visual Analytics In Explaining Neural Networks With Neuron Clustering, Gulsum Alicioglu, Bo Sun Apr 2024

Visual Analytics In Explaining Neural Networks With Neuron Clustering, Gulsum Alicioglu, Bo Sun

College of Science & Mathematics Departmental Research

Deep learning (DL) models have achieved state-of-the-art performance in many domains. The interpretation of their working mechanisms and decision-making process is essential because of their complex structure and black-box nature, especially for sensitive domains such as healthcare. Visual analytics (VA) combined with DL methods have been widely used to discover data insights, but they often encounter visual clutter (VC) issues. This study presents a compact neural network (NN) view design to reduce the visual clutter in explaining the DL model components for domain experts and end users. We utilized clustering algorithms to group hidden neurons based on their activation similarities. …


Unlv Mental Health Initiatives: Unifying Through Innovation And Collaboration, The Lincy Institute, Unlv Practice, Behere Nv, Unlv Department Of Psychology Apr 2024

Unlv Mental Health Initiatives: Unifying Through Innovation And Collaboration, The Lincy Institute, Unlv Practice, Behere Nv, Unlv Department Of Psychology

Lincy Institute Events

Nevada persistently ranks at or near the bottom in the country for overall access to mental health services despite the need (Mental Health America, 2015-2023). UNLV faculty are developing initiatives to change this unacceptable situation. The Lincy Institute, in partnership with UNLV PRACTICE, BeHERE Nevada, and researchers from the Department of Psychology, offered a community forum showcasing three mental health initiatives harnessing faculty collaboration and innovation to drive overdue changes in Nevada’s mental-health landscape. Following the presentations policymakers engaged in open discussion with UNLV presenters and the audience. The three main initiatives showcased in this forum …


Liver-Directed Locoregional Therapies For Neuroendocrine Liver Metastases: Recent Advances And Management., Cody R Criss, Mina S Makary Apr 2024

Liver-Directed Locoregional Therapies For Neuroendocrine Liver Metastases: Recent Advances And Management., Cody R Criss, Mina S Makary

Oncology Articles

Neuroendocrine tumors (NETs) are a heterogeneous class of cancers, predominately occurring in the gastroenteropancreatic system, which pose a growing health concern with a significant rise in incidence over the past four decades. Emerging from neuroendocrine cells, these tumors often elicit paraneoplastic syndromes such as carcinoid syndrome, which can manifest as a constellation of symptoms significantly impacting patients' quality of life. The prognosis of NETs is influenced by their tendency for metastasis, especially in cases involving the liver, where the estimated 5-year survival is between 20 and 40%. Although surgical resection remains the preferred curative option, challenges emerge in cases of …


Improved Cardiac Auscultation Competency Interweaving Visual, Auditory, And Tactile Stimuli: A Preliminary Study, Harrison A Patrizio, Riley Phyu, Bum Kim, Nils V Brolis Apr 2024

Improved Cardiac Auscultation Competency Interweaving Visual, Auditory, And Tactile Stimuli: A Preliminary Study, Harrison A Patrizio, Riley Phyu, Bum Kim, Nils V Brolis

Rowan-Virtua School of Osteopathic Medicine Departmental Research

METHODS: A pilot randomized controlled trial was conducted at our institution's simulation center with 32 first year medical students from a single medical institution. Participants were randomly divided into two equal groups and completed an educational module on the identification and pathophysiology of five common cardiac sounds. The control group utilized traditional education methods, while the interventional group incorporated multisensory stimuli. Afterwards, participants listened to randomly selected cardiac sounds and competency data was collected through a multiple-choice post-assessment in both groups. Mann-Whitney U test was used to analyze the data.

Results: Data were analyzed using the Mann-Whitney U test. Diagnostic …


Changes In Reef Tourism’S Adaptive Capacity After Severe Climate Disturbances, Henry Bartelet, Michele Barnes, Lalu Bakti, Graeme S. Cumming Apr 2024

Changes In Reef Tourism’S Adaptive Capacity After Severe Climate Disturbances, Henry Bartelet, Michele Barnes, Lalu Bakti, Graeme S. Cumming

Quantitative Methods and Information Technology Faculty Publications

Knowledge about adaptive capacity and its determinants has increased significantly over the last decade. However, most research on adaptive capacity has been static, not considering how adaptive capacity might change over time, particularly after severe disturbances. We studied the adaptive capacity dynamics of Asian-Pacific reef tourism operators affected by coral bleaching and tropical cyclones compared with a control group with non-affected operators. We found that impacts from tropical cyclones were associated with frequent changes in adaptive capacity. Notably, we found a reduction in tangible attributes (assets and flexibility) of adaptive capacity, whereas intangible attributes (agency and social organization) increased. Our …


The Student Movement Volume 108 Issue 20: Breaking News: Curfew Is Now Sunset: Effective Immediately, Grace No, Reagan Mccain, Savannah Tyler, Madison Vath, Corinna Bevier, Nate Miller, Aiko J. Ayala Rivers, Andrew Francis, Ana K. Zelidon, Jonathan Clough, Abby Shim, Bella Hamann, Anna Rybachek, Melissa Moore, Nicholas Gunn Apr 2024

The Student Movement Volume 108 Issue 20: Breaking News: Curfew Is Now Sunset: Effective Immediately, Grace No, Reagan Mccain, Savannah Tyler, Madison Vath, Corinna Bevier, Nate Miller, Aiko J. Ayala Rivers, Andrew Francis, Ana K. Zelidon, Jonathan Clough, Abby Shim, Bella Hamann, Anna Rybachek, Melissa Moore, Nicholas Gunn

The Student Movement v. 108 (2023-2024)

HUMANS

Chivalry Not Dead: Students Spotted in Shining Armor, Grace No

Interview with the Breakfast Burrito, Interviewed by Regan McCain

VeggieTales Cast: Hot Takes From the Fridge, Interviewed by Savannah Tyler

ARTS & ENTERTAINMENT

Why the 'Daughters of the Revolution' Stay Mad, Madison Vath

Jaws 6: The Jawsical, Corinna Bevier

I UNDERSTAND MARY POPPINS' ESSENCE MORE THAN THE FILM'S WRITERS, Nate Miller

Pitagorical decision: Music Department opens Triangle Performance Major, Aiko J. Ayala Rivers

Sabrina Carpenter Comes to Berrien, Reagan McCain

NEWS

Soccer (Football) Legend Lionel Messi to Visit Berrien County, Andrew Francis

Satire: Severe Weather Stirs Mixed Emotions on …


Brief Of Amicae Curiae Susan Boundy-Sanders And Paula Waters In Support Of Friends Of Sammamish Valley And Futurewise, King County V. Friends Of Sammamish Valley, Washington State Supreme Court Docket No. 102177-1, William Bailey Apr 2024

Brief Of Amicae Curiae Susan Boundy-Sanders And Paula Waters In Support Of Friends Of Sammamish Valley And Futurewise, King County V. Friends Of Sammamish Valley, Washington State Supreme Court Docket No. 102177-1, William Bailey

Court Briefs

No abstract provided.


Predicting The Potential Distribution Of Pseudococcus Longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) In South Korea Using A Climex Model, Su Bin Kim, Soo-Jung Suh Apr 2024

Predicting The Potential Distribution Of Pseudococcus Longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) In South Korea Using A Climex Model, Su Bin Kim, Soo-Jung Suh

Insecta Mundi

Pseudococcus longispinus (Targioni-Tozzetti) (Hemiptera: Pseudococcidae) is a widely-distributed pest that feeds on many economically important hosts, particularly tropical fruits and ornamentals. The potential distribution of this mealybug pest in South Korea remains a primary concern because of its high incidence of interceptions screened during inspection. Hence, this species prompted a modelling effort to assess its potential risk of introduction. Potential risk maps were developed for this pest with a CLIMEX model based on occurrence records under environmental data. The potential distribution of these pests in South Korea in the 2020s, 2050s and 2090s was projected based on the RCP 8.5 …


Integrating Restorative Practices To Create Equitable Disciplinary Process, Vivian Ngo Apr 2024

Integrating Restorative Practices To Create Equitable Disciplinary Process, Vivian Ngo

Doctor of Education (EdD)

The process of punitive disciplinary processes are shifting in K-12 educational institutions. This study explored the implementation of a school-wide disciplinary process that integrates the philosophy of restorative justice and its practices. The goal of the study was to reduce the amount of punitive punishment, address social issues of bullying and discrimination, and improve the overall school climate. During the study, data revealed the overall importance of implementing teacher training so that the staff understands the long-term impact of restorative justice to successfully implement the practices. My dissertation also revealed through the use of mixted methods, the importance of using …


Library Newsletter: April 2024, Iwasaki Library Apr 2024

Library Newsletter: April 2024, Iwasaki Library

Iwasaki Newsletters

This newsletter series includes information about Libray collections, services, spaces, and more!


Evaluation Of Yield And Physicochemical Quality Of Pentadesma Butyracea Butter Obtained By Different Traditional Extraction Methods In Ghana, Josephine Akuba Timtey, Francis Alemawor, William Otoo Ellis, Jacob K. Agbenorhevi, Nana Baah Pepra-Ameyaw Apr 2024

Evaluation Of Yield And Physicochemical Quality Of Pentadesma Butyracea Butter Obtained By Different Traditional Extraction Methods In Ghana, Josephine Akuba Timtey, Francis Alemawor, William Otoo Ellis, Jacob K. Agbenorhevi, Nana Baah Pepra-Ameyaw

Food Science Faculty Articles and Research

Pentadesma butyracea seed butter or fat (PBSB) is a vegetable fat extracted from the seeds of the P. butyracea plant. The butter has potential use in the food, pharmaceutical, and cosmetic industries. The study investigated traditional PBSB processing methods in Ghana and evaluated their effects on yield, physicochemical parameters, and fatty acid composition. Four traditional extraction methods were identified and evaluated, and these methods are direct wet extraction of PBSB from a fresh mixture of the seed paste and water (DEW); wet extraction of PBSB from a 12-hour fermented mixture of the seed paste and water (FWO); direct wet extraction …


Sga 55 Senate 2024-04-05 Agenda, Niu Student Government Association Senate Apr 2024

Sga 55 Senate 2024-04-05 Agenda, Niu Student Government Association Senate

Student Government Association Archives

No abstract provided.


The Monetary Structure Of Economic Activity: A Constitutional Analysis, Christine Desan Apr 2024

The Monetary Structure Of Economic Activity: A Constitutional Analysis, Christine Desan

Law and Contemporary Problems

No abstract provided.


"Just What Is Going On Here?" An Homage, Barak D. Richman Apr 2024

"Just What Is Going On Here?" An Homage, Barak D. Richman

Law and Contemporary Problems

No abstract provided.


Evidence-Based Programs For System-Involved Youths, Karli Baalmann, April Terry Apr 2024

Evidence-Based Programs For System-Involved Youths, Karli Baalmann, April Terry

SACAD: Scholarly Activities

Far too many juveniles are incarcerated in juvenile correctional facilities, and in some cases, waived into the adult criminal legal system. Life course theory helps explain this pathway as many of these youth grow up in poverty-stricken environments, with restricted access and poor quality of schooling, during which they may experience abuse and neglect, leading them into the school-to-prison pipeline. Likewise, youth experiencing Adverse Childhood Experiences (ACEs)—forms of abuse, neglect, and household dysfunction—endure the additional abuse-to-prison pipeline. Once incarcerated, these youth experience reentry issues when attempting to successfully transition back into their homes and communities. However, this issue starts before …


Harnessing Exosomes As A Platform For Drug Delivery In Breast Cancer: A Systematic Review For In Vivo And In Vitro Studies, Abdulwahab Teflischi Gharavi, Saeed Irian, Azadeh Niknejad, Keykavous Parang, Mona Salimi Apr 2024

Harnessing Exosomes As A Platform For Drug Delivery In Breast Cancer: A Systematic Review For In Vivo And In Vitro Studies, Abdulwahab Teflischi Gharavi, Saeed Irian, Azadeh Niknejad, Keykavous Parang, Mona Salimi

Pharmacy Faculty Articles and Research

Breast cancer remains a significant global health concern, emphasizing the critical need for effective treatment strategies, especially targeted therapies. This systematic review summarizes the findings from in vitro and in vivo studies regarding the therapeutic potential of exosomes as drug delivery platforms in the field of breast cancer treatment. A comprehensive search was conducted across bibliographic datasets, including Web of Science, PubMed, and Scopus, using relevant queries from several related published articles and the Medical Subject Headings Database. Then, all morphological, biomechanical, histopathological, and cellular-molecular outcomes were systematically collected. A total of 30 studies were identified based on the Preferred …


J.R. Bronze Corp. V. Watson Apr 2024

J.R. Bronze Corp. V. Watson

All Decisions

In this holdover nuisance proceeding, the landlord failed to prove that the tenant's alleged unsanitary disposal of cat waste affected other tenants or the building. The court found no evidence of ongoing nuisance conduct and dismissed the case, underscoring the need for a consistent pattern of objectionable behavior to substantiate such claims.


Implementing Teach Back Heart Failure Education To Improve Self-Care And Reduce Re-Hospitalization: A Quality Improvement Project, Sweata Patel Apr 2024

Implementing Teach Back Heart Failure Education To Improve Self-Care And Reduce Re-Hospitalization: A Quality Improvement Project, Sweata Patel

DNP Projects

Heart failure (HF) is a major health concern. External evidence supports the use of the teach-back method for patient education to promote self-care behaviors in patients with HF which may also reduce rehospitalizations. Patients with HF at one home health agency in New England participated in the quality improvement project which consisted of delivering 20 minute weekly standardized teach-back educational sessions covering topics of HF self-care over six weeks. The existing patient education materials and two new resources, Medication Tracker and Self-Check Plan for HF management, were reviewed. Three questions from the Self-Care of Heart Failure Index were asked during …