Digital Commons Network^™

Ablation Of Sam50 Is Associated With Fragmentation And Alterations In Metabolism In Murine And Human Myotubes, Bryanna Shao, Mason Killion, Ashton Oliver, Chia Vang, Faben Zeleke, Kit Neikirk, Zer Vue, Edgar Garza‐Lopez, Jian‐Qiang Shao, Margaret Mungai, Jacob Lam, Qiana Williams, Christopher T. Altamura, Aaron Whiteside, Kinuthia Kabugi, Jessica Mckenzie, Maria Ezedimma, Han Le, Alice Koh, Estevão Scudese, Larry Vang, Andrea G. Marshall, Amber Crabtree, Janelle I. Tanghal, Dominique Stephens, Ho‐Jin Koh, Brenita C. Jenkins, Sandra A. Murray, Anthonya T. Cooper, Clintoria Williams, Steven M. Damo10 M. Damo, Melanie R. Mcreynolds, Jennifer A. Gaddy Gaddy, Celestine N. Wanjalla, Heather K. Beasley, Antentor Hinton Jr.

Biology Faculty Research

The sorting and assembly machinery (SAM) Complex is responsible for assembling β‐barrel proteins in the mitochondrial membrane. Comprising three subunits, Sam35, Sam37, and Sam50, the SAM complex connects the inner and outer mitochondrial membranes by interacting with the mitochondrial contact site and cristae organizing system complex. Sam50, in particular, stabilizes the mitochondrial intermembrane space

bridging (MIB) complex, which is crucial for protein transport, respiratory chain complex assembly, and regulation of cristae integrity. While the role of Sam50 in mitochondrial structure and metabolism in skeletal muscle remains unclear, this study aims to investigate its impact. Serial block‐face‐scanning electron microscopy and computer‐assisted …

The Family History Of Jeremy E. Peters, Jeremy E. Peters

Your Family in History: HIST 550/700

Jeremy E. Peters authored this family history as part of the course requirements for HIST 550/700 Family History offered online in Spring 2024 and was submitted to the Pittsburg State University Digital Commons. Please contact the author directly with any questions or comments: [email protected]

Gardner-Webb College Of Education Hires New Faculty Members, Office Of University Communications

Gardner-Webb NewsCenter Archive

The Gardner-Webb University College of Education has announced the hiring of multiple new faculty members. These educators will enhance undergraduate and graduate programs with their knowledge and experience in curriculum and instruction, STEM education, and leadership.

The Insufficiency Of The Causal Mechanisms Of Scientific Naturalism, Aaron R. Crosby

Masters Theses

Chance and physical necessity, serving as the two accepted causal mechanisms of scientific naturalism, are incapable of explaining the origins of gravity, the gravitational constant, and other fine-tuning parameters associated with Big Bang Cosmology. This thesis explores the origins of Scientific Naturalism, the discovery of fine-tuning parameters associated with Big Bang Cosmology, and several theories proposed under the paradigm of scientific naturalism that attempt to explain, through either chance or physical necessity, how the universe originated.

A Contemporary Pauline Apologetic Toolkit, Jayne Bertovich

Masters Theses

This thesis recounts that societal history is repeating itself in modern times whereby there is a pattern of similarity with the Millennials and Generation Z and ancient audiences of the Apostle Paul in terms of paganism and humanism at the forefront of hearts and minds pushing back on Christianity (albeit today’s exposure to post-modernism and digital influences do not present in the ancient world of the Apostle Paul). Similarly, the ancient world was interested in the advances of its day of science and philosophy. The Millennials and Generation Z population, a majority of the population globally, are ripe for the …

Noticing The Brush Strokes: Literary Markers In Hebrew Narratives, Shelbey Hunt

Masters Theses

As the people who set out to write, edit, and form the Bible may have used embellishments to enhance their narratives, could they also have left literary markers to help the reader chart a course between the historical and the enhanced? The purpose of this thesis is to find these literary markers. Exposing any potential grammatical or syntactical signpost can help the reader understand how they should view a given Biblical story and help reveal the messages the authors behind the scripture were sharing. The book of Jonah will be used as a case study to both discover and elaborate …

Imputation Of 3d Genome Structure By Genetic-Epigenetic Interaction Modeling In Mice., Lauren Kuffler, Daniel A Skelly, Anne M Czechanski, Haley J Fortin, Steven C. Munger, Christopher L. Baker, Laura G Reinholdt, Gregory W. Carter

Faculty Research 2024

Gene expression is known to be affected by interactions between local genetic variation and DNA accessibility, with the latter organized into three-dimensional chromatin structures. Analyses of these interactions have previously been limited, obscuring their regulatory context, and the extent to which they occur throughout the genome. Here, we undertake a genome-scale analysis of these interactions in a genetically diverse population to systematically identify global genetic-epigenetic interaction, and reveal constraints imposed by chromatin structure. We establish the extent and structure of genotype-by-epigenotype interaction using embryonic stem cells derived from Diversity Outbred mice. This mouse population segregates millions of variants from eight …

Osint Research Studios: A Flexible Crowdsourcing Framework To Scale Up Open Source Intelligence Investigations, A. Mukhopadhyay, Sukrit Venkatagiri, K. Luther

Computer Science Faculty Works

Open Source Intelligence (OSINT) investigations, which rely entirely on publicly available data such as social media, play an increasingly important role in solving crimes and holding governments accountable. The growing volume of data and complex nature of tasks, however, means there is a pressing need to scale and speed up OSINT investigations. Expert-led crowdsourcing approaches show promise, but tend to either focus on narrow tasks or domains, or require resource-intense, long-term relationships between expert investigators and crowds. We address this gap by providing a flexible framework that enables investigators across domains to enlist crowdsourced support for discovery and verification of …

The Storm In The Barn

Theatre Programs

No abstract provided.

Compliance Design Options For Offline Cbdcs: Balancing Privacy And Aml/Cft, Panagiotis Michalopoulos, Odunayo Emmanuel Olowookere, Nadia Pocher, Johannes Sedlmeir, Andreas Veneris, Poonam Puri

Conference Papers

Many central banks are researching and piloting digital versions of fiat money, specifically retail Central Bank Digital Currencies (CBDCs). Core to these systems’ design is the ability to perform transactions even without network connectivity. Due to the lack of direct involvement of third parties in these offline transfers, various regulatory requirements that are key in the financial space need to be accommodated. This paper deploys a compliance-by-design approach to evaluate technologies that can balance privacy with anti-money laundering and counterterrorism financing (AML/CFT) measures. It classifies privacy design options and corresponding technical building blocks for offline CBDCs, along with their impact …

Volume Cxliii, Number 20, April 26, 2024, Lawrence University

The Lawrentian

No abstract provided.

Multi-Institution Single Geometry Plan Complexity Characteristics Based On Iroc Phantoms, Vimal Desai, Zacariah Labby, Wesley Culberson, Larry Dewerd, Stephen Kry

Department of Radiation Oncology Faculty Papers

BACKGROUND: Clinical intensity modulated radiation therapy plans have been described using various complexity metrics to help identify problematic radiotherapy plans. Most previous studies related to the quantification of plan complexity and their utility have relied on institution-specific plans which can be highly variable depending on the machines, planning techniques, delivery modalities, and measurement devices used. In this work, 1723 plans treating one of only four standardized geometries were simultaneously analyzed to investigate how radiation plan complexity metrics vary across four different sets of common objectives.

PURPOSE: To assess the treatment plan complexity characteristics of plans developed for Imaging and Radiation …

Preparing The Ground To Influence Humanitarian Sector Policies, Guidelines, And Strategies In Uganda: Case Study Two, The Baobab Research Programme Consortium

Humanitarian Task Force

This case study describes the pathway by which the Baobab Research Programme Consortium's efforts have created a platform that is primed for influencing humanitarian sector policies, guidelines, and strategies with evidence and evidence-based approaches.

Proposal: How Does The Total Sugar Intake Impact Cognitive Function In Children 10 Years Of Age?, Andrew O. Laidlaw, Camila Arrieta, Shoshana Yachnes

Department of Nutrition Student Projects

The effects that high sugar intake has on cognitive function is an ongoing topic in research today. Although most studies point to a negative relationship between the variables, the evidence is not conclusive enough to be able to confirm its true effect. While evidence finds an association between high sugar intake and chronic diseases, its impact on cognitive function is yet to be determined. The purpose of this proposed research study is to examine how total sugar intake impacts the cognitive function in children. Fifty children, age 10, will be randomly chosen from schools in South Florida for a cross-sectional …

Piezochromic Behavior Of 2,4,6-Triphenylpyrylium Tetrachloroferrate, Princess Canasa, David King, Petrika Cifligu, Adrian F. Lua Sanchez, Si L. Chen, Haesook Han, Trimaan Malik, Brant Billinghurst, Jianbao Zhao, Changyong Park, George R. Rossman, Michael Pravica, Pradip K. Bhowmik, Egor Evlyukhin

Chemistry and Biochemistry Faculty Research

In advanced photonics, there is a growing interest in piezochromic luminescent materials that exhibit multicolor switching, driven by their potential applications in optical recording, memory, and sensors. Here, the piezochromic behavior of 2,4,6-triphenylpyrylium tetrachloroferrate (Py-FeCl₄) under high pressures from 0 to 9 GPa is reported. The observed multicolor changing properties of Py-FeCl₄ (yellow–orange–red–maroon–black) are found to be fully reversible upon decompression to ambient conditions. The mechanism of Py-FeCl₄ piezochromism is investigated via Raman, infrared, and UV–vis spectroscopy combined with powder X-ray Diffraction. The absence of structural phase transitions as well as the abrupt shifts of bandgap …

Enabling Low-Cost Server Level Power Monitoring In Data Centers Using Conducted Emi, Pranjol Sen Gupta, Zahidur Talukder, Tasnim Azad Abir, Mohammad A. Islam, Phuc Nguyen

Association of Computing Machinery Open Access Agreement Publications-Archive

Server-level power monitoring in data centers can significantly contribute to its efficient management. Nevertheless, due to the cost of a dedicated power meter for each server, most data center power management only focuses on UPS or cluster-level power monitoring. In this paper, we propose a low-cost novel power monitoring approach that uses only one sensor to extract power consumption information of all servers. We utilize the conducted electromagnetic interference (EMI) of server power supplies to measure their power consumption from non-intrusive single-point voltage measurements. We present a theoretical characterization of conducted EMI generation in server power supply and its propagation …

Impact Of Fall Education To Oncology Staff On Oncology Patient Fall Rates, Danni Sloane

Articles, Abstracts, and Reports

Significance & Background

Falls and fall-related injuries impact patients' health outcomes and are the most commonly reported adverse event in hospitals. Patient falls also affect reimbursement rates and can increase length of stay by about 6.3 days and increase undue patient harm. An increase of patients falls on the medical and surgical oncology acute care units have caused undue physical harm, increased moral distress, mental fatigue, and burnout in nurses; as well as placing financial burdens on the healthcare system. Implementing fall education and interventions aligns with national patient safety goals, is a top-priority project, is in alignment with the …

Priming Through Persuasion: Towards Secure Password Behavior, Rizu Paudel, Mahdi Nasrullah Al-Ameen

Computer Science Student Research

Users tend to create weak passwords even for the important accounts. The prior research shed light on user’s insecure password behavior, and why the interventions, including requirement specification (e.g., password composition policies) and feedback systems (e.g., password meters) fail in practice. To this end, we propose and evaluate the concept: priming-through-persuasion in the realm of secure password creation. In particular, we created visual designs, aimed at priming users about the repercussions of weak passwords before their password creation. We base our designs on two forms of persuasion methods: pathos and logos. Pathos appeals to people’s emotion in order to persuade …

Mall Chevrolet Inc V. General Motors Llc

2024 Decisions

USDC for the District of New Jersey

Kathleen Wright-Gottshall V. State Of New Jersey

2024 Decisions

USDC for the District of New Jersey

Student Veterans’ Transition To Nursing Education: Barriers And Facilitators, Bruce P. Hunter, Steven Busby Dr., Jeannie Giese Dr., David Phillippi Dr.

DNP Projects

Student Veterans’ Transition to Nursing Education: Barriers and Facilitators

Abstract

The transition for student veterans from military service to higher education can be a challenging endeavor, especially for those pursuing an education in nursing. While the experiences and perspectives of each student veteran is unique, their successful integration into an academic environment can be influenced by a complex array of barriers and facilitators. This mixed-methods study aims to explore the themes and concepts that can be found in the transition experiences of student veterans in nursing education, with a focus on identifying the barriers they face and the facilitators that …

Promoting Mental Health And Well-Being Among Undergraduate Nursing Students: A Practice Guideline, Armen Mailyan

DNP Projects

Poor mental health and well-being among undergraduate nursing students negatively affects social dynamics, communication, decision making, and stress management, thus compromising the quality of healthcare delivery and patient care outcomes. It is imperative that nursing programs support students to develop positive self-care, resilience, and mental health skills while in school to foster their well-being, enhance their academic success, and to promote high-quality, patient-centered care in their future practice. The purpose of this Doctor of Nurse Practice (DNP) project was to develop a mental health and well-being practice guideline with a comprehensive set of evidence-based interventions for academic nursing programs to …

Charge The Cockpit Or Die: An Anatomy Of Fear-Driven Political Rhetoric In American Conservatism, Daniel Hostetter

Senior Honors Theses

Subthreshold negative emotions have superseded conscious reason as the initial and strongest motivators of political behavior. Political neuroscience uses the concepts of negativity bias and terror management theory to explore why fear-driven rhetoric plays such an outsized role in determining human political actions. These mechanisms of human anthropology are explored by competing explanations from biblical and evolutionary scholars who attempt to understand their contribution to human vulnerabilities to fear. When these mechanisms are observed in fear-driven political rhetoric, three common characteristics emerge: exaggerated threat, tribal combat, and religious apocalypse, which provide a new framework for explaining how modern populist leaders …

Can Time Really Heal: The Long-Term Impacts Of Joint Custody Arrangements, Savannah Mccullough

Senior Honors Theses

Due to a growing diversity of family structures, children grow up in a variety of living arrangements, especially if their parents are separated or divorced. The most common solution for these divorced families is joint custody or dual-residence arrangements, where children spend up to 50% of their time in each parent's household. The current literature on the effects of joint custody arrangements shows mixed results for children's overall adjustment and well-being, which seem to depend more on moderating factors like the child's age, exposure to interparental conflict, and parent-child relationship quality. This thesis reviews the existing literature on the advantages …

"Who Wrote The Epistle, God Only Knows": A Statistical Authorial Analysis Of Hebrews In Comparison With Pauline And Lukan Literature, Benjamin J. Erickson

Senior Honors Theses

The authorship of Hebrews has been a point of contention for scholars for the past two millennia. While the epistle is traditionally attributed to Paul, many scholars assert that it carries thematic, structural, and stylistic differences from the remainder of his extant epistles; therefore, many other possible authors have been proposed. Of these, only Luke has other New Testament writings. Therefore, this project conducts a statistical comparison of Hebrews to the Pauline and Lukan corpora using stylometric authorial analysis methods. This analysis demonstrates that Hebrews is stylistically closer to Lukan literature than Pauline (but not to a significant degree), and …

Normrank Correlations For Testing Associations And For Use In Latent Variable Models, Daniel B. Wright

Educational Psychology, Leadership, and Higher Education Faculty Research

Pearson’s correlation is widely used to test for an association between two variables and also forms the basis of several multivariate statistical procedures including many latent variable models. Spearman’s p is a popular alternative. These procedures are compared with ranking the data and then applying the inverse normal transformation, or for short the normrank transformation. Using the normrank transformation was more powerful than Pearson’s and Spearman’s procedures when the distributions have less than normal kurtosis (platykurtic), when the distributions have greater than normal kurtosis (leptokurtic), and when the distribution is skewed. This is examined for testing if there is an …

“Young In Deed”: Feminine Affect And Agency In Young Adult Shakespeare Adaptations, Juliana Hall

English

Approaching the cultural behemoth that is Shakespeare can be daunting, especially for young audiences; the language is antiquated and can be difficult to understand, and, due in part to the age of these works, the content is often rooted in bigoted ideologies. Young adult (YA) novel adaptations have begun reintroducing readers to Shakespeare, not only significantly enhancing the narratives, but encouraging readers to play with Shakespeare’s language in new, accessible, and exciting ways. By looking at two twenty-first century YA novel adaptations of Shakespeare’s original plays alongside the accompanying source material, I analyze how female protagonists engage with their emotions …

Structural Homology Of Mite Profilins To Plant Profilins Is Not Indicative Of Allergic Cross-Reactivity, Andrea O'Malley, Sahana Sankaran, Avery Carriuolo, Kriti Khatri, Krzysztof Kowal, Maksymilian Chruszcz Ph.D.

Faculty Publications

Structural and allergenic characterization of mite profilins has not been previously pursued to a similar extent as plant profilins. Here, we describe structures of profilins originating from Tyrophagus putrescentiae (registered allergen Tyr p 36.0101) and Dermatophagoides pteronyssinus (here termed Der p profilin), which are the first structures of profilins from Arachnida. Additionally, the thermal stabilities of mite and plant profilins are compared, suggesting that the high number of cysteine residues in mite profilins may play a role in their increased stability. We also examine the cross-reactivity of plant and mite profilins as well as investigate the relevance of these profilins …

Disney's Newsies:The Musical

Taylor Theatre Playbills

The playbill for Taylor University's performance of Disney's Newsies:The Musical. Book by Harvey Fierstein. Music by Alen Menken. Lyrics by Jack Feldman.

Performed April 26-28 & May 3-5, 2024 at the Mitchell Theatre.

Disney's Newsies is a vibrant and inspiring musical based on the 1992 film and inspired by the real-life Newsboys Strike of 1899 in New York City. The story follows Jack Kelly, a charismatic newsboy who dreams of a better life. When newspaper publisher Joseph Pulitzer raises the prices that newsies must pay for papers, Jack and his fellow newsboys form a union and organize a strike to …

Autism And The Body Of Christ: Understanding, Accommodating, And Accepting Autistic Believers In The Church, Kaitlyn Cook

Senior Honors Theses

Autism is a neurotype that causes a different set of strengths and weaknesses and thus should be embraced and accommodated within the church. Not only are autistic believers able to grasp Christian concepts, but they also have different perspectives and skills that can be instrumental in building up the church. Promoting a correct view of autism and accommodating neurodiversity within the church will allow autistic believers to follow God’s command to be part of a body and build up the church. The church can employ several strategies to create an accessible environment for believers on the spectrum, including creating sensory-safe …