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Articles 140671 - 140700 of 1826529
Full-Text Articles in Entire DC Network
Research On General Drawing Design Technologies For Cover Culverts In Hunan Province, Peng Xiaoming, Li Yukun, Hu Qiong, Xia Yutao
Research On General Drawing Design Technologies For Cover Culverts In Hunan Province, Peng Xiaoming, Li Yukun, Hu Qiong, Xia Yutao
Journal of China & Foreign Highway
As one of the main structures of highways,a culvert has the characteristics of large quantity and wide range.Affected by design and construction factors,engineering diseases of culverts have been prominent for a long time.With the extensive promotion of the green highway construction concept and the continuous updating of technical standards and design specifications,the original general drawing of culverts fails to meet the needs of the sustainable and healthy development of highway construction under the new situation.Hunan Provincial Communications Planning,Survey & Design Institute has conducted extensive and in-depth investigation and research on the key technologies of highway culvert design and prepared a …
Protection Design Of Middle Piers Of Overpass Bridges Based On Double Protection Concept, Lyu Sizhong, Wang Xin, Guo Jianmin, Liu Siyuan, Li Yuxin, Yang Fuyu
Protection Design Of Middle Piers Of Overpass Bridges Based On Double Protection Concept, Lyu Sizhong, Wang Xin, Guo Jianmin, Liu Siyuan, Li Yuxin, Yang Fuyu
Journal of China & Foreign Highway
The collision accident types of middle piers of overpass bridges were summarized and analyzed,and it was proven that anti-collision and anti-scratching were two important requirements of pier protection.Then,the new concept of double protection and corresponding technical schemes were put forward.The first protection adopted the way of setting concrete barriers or ship-shaped elevating members on the periphery of the pier to prevent vehicles from impacting the pier,and the second protection used the self-wrapped steel plate or aluminum foam plate to prevent vehicles from scratching the pier.The safety of the pier protection structure schemes was verified by computer simulation and unit test,and …
Research On Yolov 5‑Ganomaly Joint Algorithm For High‑Strength Bolt Detection, Xie Haibo, Zhu Weijun, Zhang Bi2, Zhang Dahai
Research On Yolov 5‑Ganomaly Joint Algorithm For High‑Strength Bolt Detection, Xie Haibo, Zhu Weijun, Zhang Bi2, Zhang Dahai
Journal of China & Foreign Highway
High-strength bolt loosening detection of bridges faces problems such as heavy workload,small targets,many anomalies,and difficult collection.Therefore,this paper proposed a semi-supervised deep learning model,which could obtain the bolt loosening detection model even with a small number of negative samples and solve the problem of unbalanced model training samples.The accuracy of the YOLOv 5-CT model for bolt target detection reached 98.33%.By preprocessing bolt data,the reconstruction ability of bolt images by the Ganomaly model was improved.When the hidden space vector value was 100,the model had the highest SAUC and the best discriminant performance.In the model test stage,the threshold of abnormal fraction was set …
Force Analysis Of Open Web Triangular Area Of Ganxi Super Bridge During Construction, Sun Keqiang, Li Baifu, Xue Qilin
Force Analysis Of Open Web Triangular Area Of Ganxi Super Bridge During Construction, Sun Keqiang, Li Baifu, Xue Qilin
Journal of China & Foreign Highway
Ganxi Super Bridge is an open web continuous rigid frame bridge with a main span of 300 m,and the upper chord box girder in the open web triangular area adopts the post support of a few telescopic columns with the hanging basket for suspension casting.The lower chord box girder adopts the full cable-stayed buckle method with a hanging basket for suspension casting.To analyze the force characteristics of the temporary structural system in the triangular area during the construction process using this method,the force variation law during the construction process of the temporary structural system in the triangular area was summarized …
Value Of Effective Length Coefficient Of Pier Of Long‑Span Continuous Rigid Frame Bridge, Tang Like, Song Suidi, Zhang Yang
Value Of Effective Length Coefficient Of Pier Of Long‑Span Continuous Rigid Frame Bridge, Tang Like, Song Suidi, Zhang Yang
Journal of China & Foreign Highway
The effective length coefficient of a pier is a controlling factor affecting the safety and economic index of bridge structures.The values of the effective length coefficient of compression members in Chinese and foreign codes are basically similar,and they are only applicable to ideal boundary conditions.In practical application,it is necessary to make appropriate adjustments according to the specific structural form.In order to get the value closer to the actual situation of the structure,this paper analyzed the overall stability of the structure and investigated the influence laws of different factors on the effective length coefficient of the continuous rigid frame bridge in …
Transverse Deformation And Countermeasures Of Cantilever Assembly Of Super‑Wide Steel Box Girder Of Zhongshan Bridge Over Shenzhen‑Zhongshan Link, Zhou Yu
Journal of China & Foreign Highway
In view of the transverse deformation of super-wide steel box girders of cable-stayed bridges during the cantilever assembly,the construction characteristics of the two-way eight-lane super-wide steel box girder of Zhongshan Bridge over Shenzhen-Zhongshan Link were analyzed,and the main causes of the transverse deformation during the cantilever assembly of the super-wide steel box girder were investigated.According to the matching height difference adjustment technology in the cantilever assembly construction of the wide box girder in China and abroad,this paper innovatively proposed a matching process of straight beam locking + initial tension of hanging cables,which better solved the problem of poor transverse deformation …
Calculation Of Slag Weight In Shield Construction Based On Compound Continuous Belt Conveyor, Zhou Biao, Ding Xiaobin, Sun Wenjian, Ren Xufeng
Calculation Of Slag Weight In Shield Construction Based On Compound Continuous Belt Conveyor, Zhou Biao, Ding Xiaobin, Sun Wenjian, Ren Xufeng
Journal of China & Foreign Highway
Based on the construction data of continuous belt conveyors in shield construction,this paper evaluates two common calculation methods of slag weight (slag weight calculation based on loosening coefficient and slag weight calculation based on external additives ) to accurately manage slag in shield construction.According to the law of slag discharged from each ring in shield construction,an improved slag weight estimation method in shield construction was proposed.The results show that there is a big error in the slag weight calculation based on the loosening coefficient.When slag weight calculation based on external additives is used,the calculated value is always smaller than the …
Fume Emission And Environmental Impact Assessment In Fresh Asphalt Tunnel Construction Site, Deng Wenti, Zou Guilian, Zhang Yuan, Yu Liang, Xie Huiduan
Fume Emission And Environmental Impact Assessment In Fresh Asphalt Tunnel Construction Site, Deng Wenti, Zou Guilian, Zhang Yuan, Yu Liang, Xie Huiduan
Journal of China & Foreign Highway
In view of the random monitori ng of fum e emission in asphalt pavement construction sites,combined with the engineering application of fresh asphalt in the construction of hot-mixed and hot-spread asphalt pavement in large and long tunnels for fume emission reduction,the fume collection and evaluation method of asphalt pavement construction sites were studied,and the emission reduction effect of fresh asphalt was evaluated.The Summa tanks were used to collect the asphalt fume at different positions of the paver,and the asphalt fume was quantitatively analyzed by gas chromatograph-mass spectrometer (GC-MS).The results show that compared with the non-fresh asphalt from the same source,the …
Temperature And Strain Development Characteristics Of Tunnel Concrete Based On Double Grating Sensors, Fang Jianping, Zhang Mengxi, Yao Xiaonan
Temperature And Strain Development Characteristics Of Tunnel Concrete Based On Double Grating Sensors, Fang Jianping, Zhang Mengxi, Yao Xiaonan
Journal of China & Foreign Highway
In order to better prevent tunnel concrete from cracking,the development law of concrete temperature and strain was studied.Based on the connection project of Sanjiang Middle Road in the Smart New City of Quzhou,a data acquisition system was established to monitor concrete temperature and strain on site.The defects of the traditional method that the temperature and strain monitoring are insensitive,and the monitoring data is discontinuous were overcome.In addition,the high-performance double grating temperature-strain sensor was used to simultaneously monitor the temperature and strain at the same position,and the temperature compensation method was used to overcome the influence of the ambient temperature on …
Comparative Study On Dynamic Effect Of Basic Longitudinal Section Alignment, Du Yongping, Wang Peng
Comparative Study On Dynamic Effect Of Basic Longitudinal Section Alignment, Du Yongping, Wang Peng
Journal of China & Foreign Highway
To improve the alignment in the old road reconstruction project,stress analysis was carried out,and the alignment and smoothness parameters were used as the major variables in the dynamic equation.A “human-vehicle-road ” dynamic analysis model was established,and alignment comparison groups were set,with only one group set with easing vertical curves.The Newmark- β method was used for programming and calculating the dynamic effects generated by the basic alignment with a radius of 7 000 m.The vibration indicators such as peak acceleration,root mean square of acceleration,vibration period,and frequency were used to analyze the dynamic effects of the basic alignment group.By analyzing the causes …
Mechanism Of Anti‑Collision Guardrails To Snow Drift Disasters On Highways, Peng Guodong, Xi Jianfeng, Zhang Siyuan, Li Min, Liu Ziwei, Xing Ruimin
Mechanism Of Anti‑Collision Guardrails To Snow Drift Disasters On Highways, Peng Guodong, Xi Jianfeng, Zhang Siyuan, Li Min, Liu Ziwei, Xing Ruimin
Journal of China & Foreign Highway
With the continuous promotion of China ’s strategy of building the country with a strong transportation network,the proportion of high-grade highways in the road network continues to increase,and the number of traffic safety facilities is increasing.Xilingol League in the Inner Mongolia Autonomous Region has a long winter and strong wind,which is one of the typical areas in China deeply affected by snow drift disasters.Through field investigation,it is found that “road snow resistance ” “visual range obstacle ” and other snow drift disasters caused by traffic safety facilities are also increasingly prominent,which seriously restricts the effective play of road transportation functions …
Innovative Exploration For Green Construction Of Highway Bridges In Dense Urban Areas, Liu Xuexin, Zeng Lei, Meng Yuanying, Hao Guojun, Chen Yao
Innovative Exploration For Green Construction Of Highway Bridges In Dense Urban Areas, Liu Xuexin, Zeng Lei, Meng Yuanying, Hao Guojun, Chen Yao
Journal of China & Foreign Highway
In order to improve the green construction level of highways in dense urban areas,the project characteristics and engineering requirements of the Nansha-Zhongshan Expressway were analyzed,and the concept of green development was implemented in the whole life cycle of highway design,construction,operation,maintenance,and management.The research and development of ten innovative technologies in four categories were highlighted,including industrial intelligent construction of highway bridges,comprehensive utilization of highway resources,environmental protection of highways in coastal wet areas,and integrated design of transportation and tourism in the Guangdong-Hong Kong-Marco Greater Bay Area.Among them,the prefabricated beam annular production line and non-standard eight-lane were the unprecedented technologies first used in the …
Construction Of Carbon Emission Monitoring And Management System For Commercial Vehicles, Chang Zheng, Song Yan, Ji Meichen, Liu Yuqing, Wang Jing
Construction Of Carbon Emission Monitoring And Management System For Commercial Vehicles, Chang Zheng, Song Yan, Ji Meichen, Liu Yuqing, Wang Jing
Journal of China & Foreign Highway
To construct a comprehensive carbon emission monitoring and management system for commercial vehicles,firstly,this article described the background and significance of carbon emission monitoring and management of commercial vehicles and summarized the research in relevant fields in China and abroad.Then,this article expounded on the carbon emission monitoring system for commercial vehicles,which covered three major levels:monitoring target layer,monitoring implementation layer,and monitoring summary layer,so as to achieve comprehensive and accurate carbon emission monitoring.Finally,combined with the carbon emission monitoring data of commercial vehicles,this article put forward a carbon emission management system for commercial vehicles based on data information,including carbon emission data sharing and opening,data …
Comparison Of Chinese , Ame Rican, And Bangladeshi Criteria For Liquefaction Judgment O F Fine‑Grained Soil, Wu Zi
Journal of China & Foreign Highway
The criteria for liquefaction judgment of fi ne-grained soil in current seismic design codes of China,the United States,and Bangladesh are quite different.In order to propose the judgment criteria for engineering application and Chinese code revision,this paper compared the judgment processes and criteria of the three countries.After analyzing the formation process,based on the application of the criteria for liquefaction judgment of 168 fine-grained soil samples collected in Dhaka,Bangladesh and surrounding cities,the rationality of each judgment process and criteria was evaluated comprehensively.Finally,a set of judgment processes and result criteria for fine-grained soil liquefaction integrating all criteria were put forward.
Verlorene Heimat, Gefundene Leere - Michael Hanekes Trilogie Der Emotionalen Vergletscherung Und Die Nicht-Orte Des Alltags, Amber Lane
Foreign Languages & Literatures ETDs
This work examines the incorporation of the concept of non-place in Michael Haneke's Trilogy of Emotional Glaciation (1989-1994) and its connection to elements of the Heimatfilm. The trilogy introduces the concept of non-place in urban or domestic settings while exploring the decay of human relationships and societal alienation. Despite individual stories, the films share a dark atmosphere and question human existence in an alienated world. Haneke's unique film style, characterized by long takes and minimalist aesthetics, is used to examine human behavior with emotional distance. This work sheds light on Haneke's contribution to the Austrian film tradition and contributes to …
Geospatial Analysis Of Environmental, Tick, And Host Interactions With Rocky Mountain Spotted Fever In The Southwestern United States, Al Ekram Elahee Hridoy
Geospatial Analysis Of Environmental, Tick, And Host Interactions With Rocky Mountain Spotted Fever In The Southwestern United States, Al Ekram Elahee Hridoy
Geography ETDs
This study examines the spatiotemporal distribution and determinants of Rocky Mountain Spotted Fever (RMSF) incidence in Arizona from 2006 to 2021. Utilizing climate variables, land cover types, and socio-economic indicators, we employed Negative Binomial Regression, Spatial autocorrelation, and Random Forest-based classification to identify key predictors and patterns of RMSF spread. Results indicate positive correlations between RMSF incidence and precipitation and shrub cover, while veterinary access, forest cover, and relative humidity show negative associations. Spatial analysis revealed significant case clustering, with limited veterinary access associated with higher RMSF incidence. A Random Forest-based predictive model was developed to identify potential tick-host interactions, …
Evaluation Of A Peer Mentoring Program In Baccalaureate Nursing Students: A Quality Improvement Project, Leigh E. Swartzendruber
Evaluation Of A Peer Mentoring Program In Baccalaureate Nursing Students: A Quality Improvement Project, Leigh E. Swartzendruber
Doctor of Nursing Practice Projects
Nursing school can be rigorous, stressful, and anxiety-producing for students trying to progress to graduation, with students leaving the program if they encounter barriers. Academia must consider strategies to support students; peer mentoring is an evidence-based approach. The project evaluated an existing peer mentoring program to understand the benefits and barriers entry-level sophomore students experience with the program, comparing survey results from 2022 and 2024 cohorts—a mixed-methods descriptive statistical study was conducted with the spring 2024 peer mentoring program. Using a PDSA cycle, the program was transformed from an in-person to a hybrid format. At the end of the program, …
Examining Food Access Equity By Integrating Grocery Store Pricing Into Spatial Accessibility Measures, Subham Kharel, Seyedsoheil Sharifiasl, Qisheng Pan
Examining Food Access Equity By Integrating Grocery Store Pricing Into Spatial Accessibility Measures, Subham Kharel, Seyedsoheil Sharifiasl, Qisheng Pan
SAGE Open Access Agreement Publications-Archive
Accessibility to food stores offering nutritious and affordable options is critical to ensure urban residents lead healthy lives. However, the uneven distribution of diverse food options in U.S. cities has raised concerns about marginalized communities’ ability to obtain affordable and nutritious food. Transportation-related issues, like car-oriented urban form and sprawl, have created food deserts in cities, making it hard for marginalized communities to access affordable and healthy food. This lack of access has recently drawn the attention of urban planners to address food access-related equity issues. Spatial interaction models can help measure food access by examining how grocery store supply, …
New Empirical Formulae For Some (P,Γ) Reactions Of Astrophysical S-Factor And Thermonuclear Reaction Rates, Mohammed Issa Hussein
New Empirical Formulae For Some (P,Γ) Reactions Of Astrophysical S-Factor And Thermonuclear Reaction Rates, Mohammed Issa Hussein
Polytechnic Journal
The study utilized weighted averages of cross sections in millibarn for (p,γ) reactions of 74Ge, 88Sr, 89Y, 90Zr, and 107Ag medium target elements from the EXFOR nuclear data library and compares them with evaluated from TALYS 1.95 nuclear model code. These averages were employed to develop empirical formulas for the astrophysical S-factor, covering proton energies up to 5 MeV, and thermonuclear reaction rates up to 20×109 K T9 (T9 is the temperature in units of 109K). Polynomial formulas have been utilized to accurately model the calculated astrophysical S-factor and thermonuclear …
Diversity, Equity And Inclusion In Simulation-Based Education: Experiences From Multiple Academic Health Centers, Jesika Samuelson Gavilanes
Diversity, Equity And Inclusion In Simulation-Based Education: Experiences From Multiple Academic Health Centers, Jesika Samuelson Gavilanes
Dissertations and Theses
The integration of Diversity, Equity and Inclusion (DEI) into healthcare professional training is critical in order to ensure positive patient outcomes and help combat healthcare disparities, leading towards health equity. There is not currently a standard specific to DEI awareness in healthcare education and training. One area of healthcare training is simulation-based education (SBE), which is training that is set up to be as close to a real environment as possible for healthcare professional training. There is little in the literature that addresses DEI within SBE, yet SBE is one area with the potential for making an impact in healthcare …
Cross-Correlation Increases Sampling In Diffusion-Based Super-Resolution Optical Fluctuation Imaging, Jeanpun Antarasen, Benjamin Wellnitz, Stephanie N. Kramer, Surajit Chatterjee, Lydia Kisley
Cross-Correlation Increases Sampling In Diffusion-Based Super-Resolution Optical Fluctuation Imaging, Jeanpun Antarasen, Benjamin Wellnitz, Stephanie N. Kramer, Surajit Chatterjee, Lydia Kisley
Faculty Scholarship
Correlation signal processing of optical three-dimensional (x, y, t) data can produce super-resolution images. The second-order cross-correlation function XC2 has been documented to produce super-resolution imaging with static and blinking emitters but not for diffusing emitters. Here, we both analytically and numerically demonstrate cross-correlation analysis for diffusing particles. We then expand our fluorescence correlation spectroscopy super-resolution optical fluctuation imaging (fcsSOFI) analysis to use cross-correlation as a postprocessing computational technique to extract both dynamic and structural information on particle diffusion in nanoscale structures simultaneously. Cross-correlation maintains the same super-resolution as auto-correlation while also increasing the sampling rates to reduce aliasing for …
The Negative Impacts Of Parentification On Adolescents: A Systematic Review, Reilly Reid Hawkins
The Negative Impacts Of Parentification On Adolescents: A Systematic Review, Reilly Reid Hawkins
Theses and Dissertations
While child abuse, maltreatment, and neglect are clear examples of the most maladaptive types of parent-child interactions (Borchet et al., 2022), there is considerable evidence for the damaging nature of parentification in terms of youth outcomes and parental/familial dysfunction. The research literature contains numerous studies related to parentification, but there is little research overtly demonstrating the systemic effects of parentification (Peris et al., 2008). It is imperative that researchers and clinicians learn more about the mechanisms involved in the parentification process. Therefore, this systematic review analyzed the research literature centered on both parentification and adolescent populations. This study assessed various …
Associations Between Coping Style And Perceptions Of Web-Delivered Physical Activity Messages Among Women In Midlife With Cardiovascular Health Risks, Kristen Pasko
Theses and Dissertations
Midlife women are at unique risk for cardiovascular disease (CVD) and benefit from increasing physical activity (PA). Many PA interventions involve social support, though fail to address related processes such as social comparison. Desire for specific types of social support and comparison may represent emotion-focused versus problem-solving coping, though little is known about women’s preferences for/responses to these coping opportunities. The present study examined women’s selections of PA content in a digital environment. Over 7 days, women in midlife ≥1 CVD risk factor (N = 60, MAge = 50.70, SD = 5.89) wore a PA monitor and visited a proprietary …
A Retrospective Analysis Of Primary Breast Cancer Surgical Procedures (Mastectomy Versus Breast Conserving Surgery) Performed On Women Living In Rural And Urban Counties In South Carolina, Talitha M. Massaquoi
A Retrospective Analysis Of Primary Breast Cancer Surgical Procedures (Mastectomy Versus Breast Conserving Surgery) Performed On Women Living In Rural And Urban Counties In South Carolina, Talitha M. Massaquoi
MUSC Theses and Dissertations
Women dealing with a diagnosis of breast cancer may be challenged when attempting to seek and obtain medical care while living in a rural community. It is not known whether geography impacts the decision-making process for women considering elective breast cancer surgery (mastectomy versus breast conserving surgery (BCS)) in South Carolina. We performed a retrospective analysis of breast cancer surgical options offered to women to examine if a difference exists in both rural and urban settings. Although there was a higher proportion of women in South Carolina who elected to undergo a mastectomy instead of BCS (4,416 [79.5%] vs. 1,139 …
Industria 4.0. Internet De Las Cosas: Ciberseguridad Y Aplicaciones, Jairo Eduardo Márquez Díaz, Arles Prieto Moreno, Luz Jaddy Castañeda Rodríguez, Luis Gonzalo Benavides Ramírez
Industria 4.0. Internet De Las Cosas: Ciberseguridad Y Aplicaciones, Jairo Eduardo Márquez Díaz, Arles Prieto Moreno, Luz Jaddy Castañeda Rodríguez, Luis Gonzalo Benavides Ramírez
Ingeniería
Este libro explora cómo la Cuarta Revolución Industrial, también conocida como Industria 4.0, está transformando sectores industriales mediante tecnologías disruptivas como el internet de las cosas (IoT), la inteligencia artificial, el big data y la realidad aumentada, lo que ofrece una mayor eficiencia, productividad y seguridad. Aborda los riesgos de ciberseguridad asociados y propone soluciones basadas en la inteligencia artificial y el blockchain. Además, analiza el uso de drones y tecnologías como el LiDAR en la minería, lo que mejora la exploración, la seguridad y la sostenibilidad de operaciones complejas. Con un enfoque en la minería del carbón en Colombia, …
Aplicación De La Serie De Fourier En La Eliminación De Armónicos Musicales Para Obtener Un Tono Puro, Kelly Johana Infante Beltrán, Néstor Orlando Forero Díaz, Adalberto Pardo Rodríguez
Aplicación De La Serie De Fourier En La Eliminación De Armónicos Musicales Para Obtener Un Tono Puro, Kelly Johana Infante Beltrán, Néstor Orlando Forero Díaz, Adalberto Pardo Rodríguez
Educación
Este libro explora la relación entre las matemáticas y la música a través de la aplicación de la serie de Fourier para eliminar armónicos y obtener tonos puros, fundamentales tanto en la audiometría médica como en la afinación de instrumentos musicales. Utilizando herramientas como Matlab y Sonic Visualiser, se analiza la pureza de las cuerdas de la guitarra clásica, destacando la importancia de esta técnica en diversos campos, desde la acústica hasta la medicina. El estudio incluye un simulador en Matlab para eliminar armónicos y una comparación de frecuencias específicas, mostrando cómo la comprensión de la serie de Fourier enriquece …
Identification Of Physical And Social Potential For Ecotourism Development In Neglasari Village, Sukabumi Regency Using Remote Sensing And Geographical Information Systems, Tjiong Giok Pin, Adi Wibowo, Haura Hazema Alya, Afifa Ayu Nastiti
Identification Of Physical And Social Potential For Ecotourism Development In Neglasari Village, Sukabumi Regency Using Remote Sensing And Geographical Information Systems, Tjiong Giok Pin, Adi Wibowo, Haura Hazema Alya, Afifa Ayu Nastiti
Jurnal Geografi Lingkungan Tropik (Journal of Geography of Tropical Environments)
Identification of physical and social potential needs to be done so that it can be developed as an ecotourism object that has a role in improving the economy of a region. Physical and social potential data can be obtained and interpreted from satellite imagery using remote sensing which is then verified through surveys and direct measurements in the field using GPS and digital maps. Data analysis was performed using the overlay method in GIS. Remote sensing methods using satellite imagery have proven to be superior for obtaining information on an area effectively and sustainably. Landsat imagery 8 and 9 are …
Quality Improvement Project: Evaluating The Impact Of An Intrapreneurial Skill Enhancement Program On Enhancing Innovation Perspectives And Overcoming Obstacles Among Nurse Practitioners At A Midwestern Academic Medical Center, Michael Thorn
Doctor of Nursing Practice Projects
Nurse practitioners (NPs) face barriers to being innovative in healthcare because of a need for more resources, education, and cultural inclusion compared to physicians and researchers (Joseph et al., 2019). NPs are often disregarded from involvement in the innovation ecosystem and seen as solely end-users of new products and services (Davis & Glasgow, 2020). This Doctor of Nursing Practice project aimed to assess the impact of a 5-week innovation and intrapreneurship course on NPs' perceptions of their ability to innovate at a Midwest academic hospital. The aim was to address the known innovation education gap that NPs rarely receive. Using …
3d Printed Mounts For Liquid Microdroplet Resonators, Parker A. Awerkamp
3d Printed Mounts For Liquid Microdroplet Resonators, Parker A. Awerkamp
Theses and Dissertations
Liquid microdroplet resonators provide an excellent tool for optical studies due to their innate smoothness and high quality factors, but they can be difficult to control. By using 3D printed mounts to support the droplets, we can obtain precise control over the droplet geometries and positions. We here present our work with oil, water, and ice microdroplets, as well as tools required to enable their study. We first present methods for creating 3D printed mounts for oil microdroplet resonators. The mounts enable precise positioning of the droplets relative to a tapered optical fiber. The oil microdroplet resonators exhibited quality factors …
Potential Targeting Mechanisms For Bone-Directed Therapies, Betul Celik, Andrés Leal, Shunji Tomatsu
Potential Targeting Mechanisms For Bone-Directed Therapies, Betul Celik, Andrés Leal, Shunji Tomatsu
Department of Pediatrics Faculty Papers
Bone development is characterized by complex regulation mechanisms, including signal transduction and transcription factor-related pathways, glycobiological processes, cellular interactions, transportation mechanisms, and, importantly, chemical formation resulting from hydroxyapatite. Any abnormal regulation in the bone development processes causes skeletal system-related problems. To some extent, the avascularity of cartilage and bone makes drug delivery more challenging than that of soft tissues. Recent studies have implemented many novel bone-targeting approaches to overcome drawbacks. However, none of these strategies fully corrects skeletal dysfunction, particularly in growth plate-related ones. Although direct recombinant enzymes (e.g., Vimizim for Morquio, Cerezyme for Gaucher, Elaprase for Hunter, Mepsevii for …