Digital Commons Network^™

An Application Of An In-Depth Advanced Statistical Analysis In Exploring The Dynamics Of Depression, Sleep Deprivation, And Self-Esteem, Muslihat Gaffari

Electronic Theses and Dissertations

Depression, intertwined with sleep deprivation and self-esteem, presents a significant challenge to mental health worldwide. The research shown in this paper employs advanced statistical methodologies to unravel the complex interactions among these factors. Through log-linear homogeneous association, multinomial logistic regression, and generalized linear models, the study scrutinizes large datasets to uncover nuanced patterns and relationships. By elucidating how depression, sleep disturbances, and self-esteem intersect, the research aims to deepen understanding of mental health phenomena. The study clarifies the relationship between these variables and explores reasons for prioritizing depression research. It evaluates how statistical models, such as log-linear, multinomial logistic regression, …

Informed Consent Document Delivery: Effects On Appalachian Caregivers' Comprehension, Trust In Researchers, And Willingness To Participate, Tess A. Simpson

Electronic Theses and Dissertations

The purpose of the present study was to investigate whether altering an informed consent document (ICD), in ways that either promote or inhibit accessibility, would affect potential participants’ willingness to participate in a child development laboratory-based study. Specifically, I was interested in assessing the willingness to participate of historically underrepresented groups, especially Appalachian caregiver-child dyads. I altered three parameters of a previously approved and employed ICD to explore whether these parameters impacted Appalachian caregivers’ comprehension of the study, willingness to participate, and trust in the researchers. The manipulated parameters included reading level, utilization of illustrative pictures, and inclusion of text-to-speech …

A Comparison Of Maxent Models For Aedes Aegypti Species Distribution In South America Utilizing Different Bioclimatic And Environmental Variables, Matthew Beer

Electronic Theses and Dissertations

Aedes aegypti is the principal vector for dengue transmission across large areas of the world. Understanding where this critically important vector lives is paramount to preventing the continued expansion of dengue globally. Using 1981-2010 bioclimatic (bioclim) variables, as well as additional environmental variables and elevation data, multiple MaxEnt models were constructed for Ae. aegypti within the South American continent to identify ecologically important variables and areas of persistent high suitability. All models had acceptable AUC scores (> 0.70), indicating accurate model fitting. Annual mean precipitation and temperature were found to be important model variables; however, when added, humidity became the …

Student Achievement In The State Of Tennessee Through Virtual Learning In Asynchronous, Bisynchronous, And Hybrid Approaches, Lindsey Weeden

Electronic Theses and Dissertations

This study was used to investigate the differences in asynchronous, bisynchronous, and hybrid learning environments in student achievement in online schools. Utilizing quantitative data analysis, the research examines student growth data, chronic absenteeism, graduation rates, and ACT scores across these modalities. The research holds significant implications for educators, policymakers, and stakeholders in enhancing the quality of online education. The results may contribute to the ongoing dialogue surrounding effective pedagogical practices in the digital age by providing evidence-based insights into the strengths and weaknesses of each instructional mode. By addressing the challenges of the digital divide, the results may be used …

An Examination Of The Physical And Technical Demands Of The Competitive Season For Ncaa Division I Male Soccer Players, Emmanuel Espinoza

Electronic Theses and Dissertations

The purposes of this dissertation were to examine the physical and technical demands of collegiate NCAA D-I male soccer players over the course of a competitive season. The following are the major findings of the dissertation:

Study 1 – GPS normative data was calculated by position using data from 5 seasons (2017, 2018, 2019, 2021, 2022). GPS data was compared by position for 5 different GPS-derived metrics. No statistically significant differences were found in any field or lab testing data by position. Statistically significant relationships were found between physical match performance variables of TD and SPR with both YYIRT-1 and …

Food Insecurity And Self-Rated Health Of Older Adults In Appalachia, Sarah Kelley

Electronic Theses and Dissertations

Food insecurity is prevalent in the United States. Although older adults experience food insecurity at lower-than-average rates, this population is vulnerable to the nutrition and health related implications. Food insecurity is tied to both a diminishment of diet quantity and quality, and is associated with incidence of chronic disease, loss of functional status, and quality of life. This survey seeks to fill a gap in research by looking into the prevalence of food insecurity among older adults in Northeast Tennessee, associations between food insecurity and self-rated health, and associations between food insecurity and geographical limitations.

Pilz Domain-Containing Proteins Regulate Motility In Acinetobacter Baumannii, Gabriel Smith

Electronic Theses and Dissertations

Acinetobacter baumannii is an increasingly multidrug-resistant pathogen contributing to hospital-acquired infections, necessitating a greater understanding of how it interacts with its surroundings. Many bacteria utilize different methods of bacterial motility to move about and interact with these surroundings. A bacterial second messenger, cyclic diguanosine monophosphate (c-di-GMP), can regulate various motility factors that are potentially advantageous for survival in and adaptation to their environment. Concentrations of c-di-GMP are regulated by specific synthesizing and degrading enzymes. Controlled levels of c-di-GMP allow interaction between the c-di-GMP and its binding effectors that induce changes in bacterial phenotypes such as biofilm formation and motility. A …

Outside The Box: Examining The School Experience From The Perspectives Of Early Leavers, Caitlin Armstrong

Electronic Theses and Dissertations

Public schools in America are experiencing a massive decline in student enrollment, resulting in school consolidations and closures across the nation. (Dee, 2023). This decline has many implications, particularly in rural areas, such as Northeast Tennessee. These implications and the public pressure to maintain high graduation rates and academic outcomes, require school leaders and policymakers to reflect on who is leaving public schools and why. This phenomenological study explored the school experiences and perceptions of individuals who left the traditional high school prior to graduation. In-depth interviews were conducted one-on-one with 13 participants via an online video conferencing platform who …

Molecular And Physiological Changes In The Spacex Inspiration4 Civilian Crew, Adrian J Ecker, Cem Meydan, Krista Ryon, Braden Tierney, Namita Damle, Matthew Mackay, Evan E Afshin, Jonathan Foox, Jiwoon Park, Theodore M Nelson, Mir Suhail Mohamad, Syed Gufran Ahmad Byhaqui, Burhan Aslam, Ummer Akbar Tali, Liaqun Nisa, Priya V Menon, Chintan O Patel, Sharib A Khan, Doug J Ebert, Aaron Everson, Michael C Schubert, Nabila N Ali, Mallika S Sarma, Jangkeun Kim, Nadia Houerbi, Kirill Grigorev, J Sebastian Garcia Medina, Alexander J Summers, Jian Gu, John A Altin, Ali Fattahi, Mohammad I Hirzallah, Jimmy H Wu, Alexander C Stahn, Afshin Beheshti, Remi Klotz, Veronica Ortiz, Min Yu, Laura Patras, Irina Matei, David Lyden, Ari Melnick, Neil Banerjee, Sean Mullane, Ashley S Kleinman, Michael Loesche, Anil S Menon, Dorit B Donoviel, Emmanuel Urquieta, Jaime Mateus, Ashot E Sargsyan, Mark Shelhamer, Frederic Zenhausern, Eric M Bershad, Mathias Basner, Christopher E Mason

Faculty, Staff and Students Publications

Human spaceflight has historically been managed by government agencies, such as in the NASA Twins Study1, but new commercial spaceflight opportunities have opened spaceflight to a broader population. In 2021, the SpaceX Inspiration4 mission launched the first all-civilian crew to low Earth orbit, which included the youngest American astronaut (aged 29), new in-flight experimental technologies (handheld ultrasound imaging, smartwatch wearables and immune profiling), ocular alignment measurements and new protocols for in-depth, multi-omic molecular and cellular profiling. Here we report the primary findings from the 3-day spaceflight mission, which induced a broad range of physiological and stress responses, neurovestibular …

Linking Physiology, Epidemiology, And Demography: Understanding How Lianas Outcompete Trees In A Changing World, Hannes De Deurwaerder, Matteo Detto, Marco Visser, Stefan A. Schnitzer, Stephen W. Pacala

Biological Sciences Faculty Research and Publications

Extending and safeguarding tropical forest ecosystems is critical for combating climate change and biodiversity loss. One of its constituents, lianas, is spreading and increasing in abundance on a global scale. This is particularly concerning as lianas negatively impact forests’ carbon fluxes, dynamics, and overall resilience, potentially exacerbating both crises. While possibly linked to climate-change-induced atmospheric CO₂ elevation and drought intensification, the reasons behind their increasing abundance remain elusive. Prior research shows distinct physiological differences between lianas and trees, but it is unclear whether these differences confer a demographic advantage to lianas with climate change. Guided by extensive datasets collected …

Stigma Reduction And Resiliency Training For First Responders (Srrt-Fr): A Feasibility And Initial Efficacy Evaluation, Thalia P. Nicholson

Electronic Theses and Dissertations

First responders, especially law enforcement, frequently encounter individuals experiencing substance use concerns. Previous research has documented that a greater understanding of substance use disorders promotes a decrease in stigmatizing perspectives. We present a novel approach to training law enforcement officers to improve their interactions with community members exhibiting substance use disorders, while also promoting their professional well-being. The present study sought to evaluate the feasibility and acceptability of the Stigma Reduction and Resiliency Training for First Responders (SRRT-FR) in a sample of law enforcement officers, as well as its efficacy in decreasing stigmatizing perspectives towards substance use disorders and increasing …

Staying Fresh: Unconventional Approaches Towards Advancing Energy Sustainability, Water Resources, And Community Resiliency In The Southwestern United States, Judith Hoyt

Open Access Theses & Dissertations

This dissertation addresses critical challenges in urban heat management, sustainable energy resource utilization, and water quality communication through three studies. Study 1 investigates the impact of roof color on urban heat islands in Tucson, Arizona where approximately 70% of roofs display high albedo (i.e., light) colors. Energy consumption simulations conducted indicate that converting dark- to light-colored roofs could save Tucson approximately $1,400,000 annually in energy costs, highlighting the potential of cool roofs for energy savings and improved thermal comfort. Study 2 assesses the sources of lithium in subsurface waters in West Texas and South Central New Mexico. Water chemistry data …

Exploring Lower Extremity Kinematics In Adolescent Baseball Players: Inside Vs. Outside Pitches From A Tee Stand, Alyssa Gabrielle Moreno

Open Access Theses & Dissertations

No abstract provided.

Neural Networks For Decisions Under Uncertainty, Edwin Tomy George

Open Access Theses & Dissertations

Neural networks are used in many real-world applications, ranging from classification tasks to medical diagnostics. For each task, a neural network is typically able to make predictions due to its ability to extract meaningful patterns from processing large amounts of data. Thus, given the increases in available data in recent decades, the performance of neural networks in making accurate predictions has greatly increased. However, this data often comes with ingrained uncertainties due to measurement errors or the inherent variability of individual data points. Neural networks can learn despite the errors in the overall data, but what if we want them …

Border Soundscapes: Latinidad, Belonging, And Sense Of Place In The Paso Del Norte Region., Josã© Manuel Flores Fuentes

Open Access Theses & Dissertations

This dissertation explores the acoustic ecologies of the Juárez-El Paso border, investigating how soundscapes shape and reflect the cultural identity, sense of belonging, and sense of place within this unique transnational region. Guided by the theoretical lenses of belonging (Kohut, Tajfel, Turner, Hooks), sense of place (Feld & Basso), and habitus (Bourdieu), the research takes a phenomenological approach, informed by Merleau-Ponty's concepts of perception and Ceraso's notion of embodied listening. The study analyzes soundscape samples through Krause's categories of biophonies, geophonies, and anthropophonies, uncovering how these sounds contribute to the development of Latino identity and cultural cohesion in the borderlands.Focusing …

Mental Health Calls For Service During The Covid-19 Pandemic: Examining The Geographic Distribution And Correlates Of Service Requests In Little Rock, Arkansas, Mckayla Bishop

Graduate Theses and Dissertations

In response to the Covid-19 global crisis, the United States implemented social interaction restrictions to curb the infection rate amongst citizens, affecting residents' mental health by adding strain from daily routine change. This study examines how mental health has changed during the pandemic by focusing on geospatial differences of volume and concentration within 311 calls in Little Rock, Arkansas in 2018 and 2020. Our data comes from the City of Little Rock’s open database to construct geospatial maps (n= 155 block groups), along with Census survey data logistic regression models to show differences in community characteristics. Overall, mental health worsened …

Experimental And Theoretical Investigation Of The Coordination Of 8-Hydroxquinoline Inhibitors To Biomimetic Zinc Complexes And Histone Deacetylase 8 (Hdac8), Anthony M. Baudino, Harris F. Ciaccio, Michael J. Turski, Xavier A. Akins, Phoebus Sun Cao, Elisa Morales, Roger D. Sommer, Adam R. Johnson, Donald J. Wink, Kyle A. Grice, Kari Stone

Chemistry Department Faculty Articles

Zinc is integral to diverse biological functions, acting catalytically, structurally, and supportively in essential enzyme cycles, despite its limited amounts in the body. Targeting zinc enzymes with potent drugs, such as Vorinostat, demonstrates the therapeutic efficacy of zinc-binding ligands, notably in cutaneous T-cell lymphoma treatments. Our study merges experimental and theoretical approaches to analyze the coordination of 8-hydroxylquinoline (8HQ) inhibitors with biomimetic zinc complexes and human histone deacetylase 8 (HDAC8), a monozinc hydrolase enzyme. Assessing 10 8HQ derivatives for structural and electronic characteristics against these models, we observe minimal inhibition efficacy, corroborated through protein–ligand docking analyses, highlighting the complexities of …

Development Of 3d Human Cardiovascular And Cancer Tissue Model Within A Self-Driven Microfluidic Platform For Preclinical Drug Screening, Aibhlin Alexis Esparza

Open Access Theses & Dissertations

According to the American Heart Association and World Health Organization, cardiovascular diseases (CVDs) are the leading cause of death worldwide. Monolayer cell culture (2D) and animal models are conventional methods to study CVDs, however, they limit researcherâ??s ability to simulate the human cardiovascular cellular microenvironments and accurate predication of pharmaceutical drug responses. Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs), biomaterials, and microfluidic technologies can be combined to create a controlled, reproducible 3D platform to study physiologically-relevant cellular responses to biochemical and physical changes in the microenvironment. My dissertation work demonstrates the development of novel self-driven microfluidic devices designed with …

La Viuda Del Panamá -- A Sixteenth-Century Novel, Maria Cecilia Herrera Astua

Open Access Theses & Dissertations

La Viuda del Panamá es una novela histórica acerca de Sir Francis Drake y su amante, María Isabel Domínguez--una viuda mestiza de quien él se enamora cuando ella lo salva de una muerte segura. Isabel oculta su ascendencia india porque, en el pueblito Nombre de Dios, esa circunstancia es un pecado social. Mas al corregidor don Pedro—un viudo quien ha tenido un matrimonio infernal—no le interesa la pureza de sangre. Nacido en un hogar judeo-musulmán, don Pedro se enamora de Isabel desde el día en que ella lo atiende en la posada La Costeña y decide ofrecerle un futuro impensable …

Don't Get Too Close, It Hurts: Inclusion-Of-Other-In-The-Self And Biased Evaluations Of Romantic Partners And Their Behaviors, Jacqueline Lechuga

Open Access Theses & Dissertations

This investigation tested how inclusion-of-other-in-the-self (IOS) – the experience of closeness as overlapping selves – increases maladaptive biases toward romantic partners and their behaviors. Study 1 tested how the level of IOS is associated with disregarding signs that indicate that a romantic partner might be unhealthy for one’s emotional and physical well-being. Participants who were single (N = 77) reviewed four online dating profiles. Each profile was created to elicit high or low IOS and reveal a transgression committed by the potential romantic partner. Then, participants evaluated the potential romantic partner in suitability and the transgression on negativity. Study 2 …

Thieves Like Us: The Effectiveness Of A Positive Psychology Intervention On Compassion Fatigue, Burnout, And The Loss Of Compassion Satisfaction Among Peer Support Specialists, Eugene Lopez

Open Access Theses & Dissertations

Two common phenomena of helping professions are compassion fatigue (CF), and decreased compassion satisfaction (CS). Literature on CF and decreased CS focuses on professionals with extensive education, training, and higher compensation. Peer Support Specialists (PSS) are helping professionals providing comparable support to clients while in recovery, and may be more susceptible to CF, decreased CS, and a return to substance use. Methods to impact these outcomes, including positive psychology interventions (PPIs), are worth investigating as they are generally inexpensive, can be tailored, and may reduce turnover and absences. The current study used the PPI, Using Signature Strengths in a New …

The Additive Effect Of Neuromuscular Electrical Stimulation On Resistance Training Induced Adaptations In Glycemic Control, Muscle Mass And Muscular Strength, Gabriel Narvaez

Open Access Theses & Dissertations

Background: Most adults do not reach the physical activity guidelines set by ACSM (>75%). Resistance training is well known to improve muscle mass, strength, and glycemic control. Neuromuscular electrical stimulation (NMES) is a mode of inducing involuntary muscle contractions. Previously, we have shown neuromuscular electrical stimulation is able to improve glycemic control. However, the effects of superimposing NMES while resistance training on glycemic control, substrate utilization and resting energy expenditure (REE) is unknown. Purpose: To investigate the effects of 8 weeks of superimposed NMES on resistance training compared to resistance training for glycemic control, substrate utilization, REE, muscle mass …

Semantic Linguistic User Profiles For Automatic Computational Narrative Creation For Scientific Models, Angel Uriel Ortega Castillo

Open Access Theses & Dissertations

The outcomes of scientific models can be hard to understand given the need for context, domain knowledge, and many variables and data being used. This research aims to provide users of scientific models with understandable information that can be automatically generated. For the context of this research, understandable is defined as being correctly interpreted (i.e., with respect to the original intent of the data). Scientific information can be conveyed to users in the form of a narrative or visualizations, and these are not necessarily separate from each other, but rather complimentary. One of the objectives of this research is to …

Random Forest For High-Dimensional Data, George Ekow Quaye

Open Access Theses & Dissertations

The exponential growth of data has led to a rapid increase in high-dimensional datasets across various domains, presenting significant challenges in data analysis, particularly in predictive modeling tasks. Traditional Random Forest (RF), while robust, often struggles with datasets filled with numerous noisy or non-informative features, compromising both performance and accuracy. This study introduces an advanced algorithm, High-Dimensional Random Forests (HDRF), designed to address these challenges by integrating robust multivariate feature selection techniques directly into the decision tree construction process. Unlike standard RF, HDRF incorporates ridge regression-based variable screening at each decision split, enhancing its ability to identify and utilize the …

Integrating Machine Learning And Simulation For Resource Planning Of Hospital Systems Based On Predicted Length Of Stay, S M Atikur Rahman

Open Access Theses & Dissertations

Recently Hospital Systems faced a high invasion of patients generated by several events such as health crisis related epidemic (COVID, FLU) or seasonal flows. Hence, managing hospital bed availability and efficiency with proper care is obligatory for addressing the challenges associated with the overburden of patients. However, the Length of stay (LOS) is often increased due to the high patient influx and overcrowding problem occurs within the Hospital. It resolves these issues, it is essential for hospital authority to predict the Patients LOS which is the crucial indicator for the use of medical resources (allocation, utilization of providers and resource) …

Quantum Circuit Optimization Leveraging Multi-Qubit Exchange Interactions In Spin Qubits, Miguel Gonzalo Rodriguez

Open Access Theses & Dissertations

This thesis looks into how multi-qubit exchange interactions can be used to improve quantumcircuits in semiconductor quantum devices. Pairwise interactions between qubits are a common tenet of traditional quantum computing paradigms, although they can impose complexity and depth constraints on circuits. In order to improve the efficiency and scalability of quantum circuits, this research explores the theoretical underpinnings and practical uses of multi-qubit interactions. A thorough theoretical framework is formulated, outlining the mathematical equivalence of a unitary matrix representing interactions between multiple qubits. We obtain the timeevolution operator by analyzing the Hamiltonian of three spin-1/2 particles. A number of quantum …

Seismic Imaging Of Mcmurdo Ice Shelf Near Williams Airfield, Yeshey Seldon

Open Access Theses & Dissertations

Seismic exploration has played a crucial role in understanding the Earth's interior and has been successfully employed in various regions, including Antarctica. This research focuses on analyzing a 1000-m seismic line on McMurdo Ice Shelf near Williams Airfield, as part of the Thwaites Interdisciplinary Margin Evolution (TIME) project. The McMurdo Ice Shelf, covering an expansive area within the Ross Ice Shelf, has undergone significant changes due to evolving oceanic and atmospheric conditions. The presence of Circumpolar Deep Water (CDW) has recently impacted the ice shelf, with warmer ocean waters causing basal melting and changes in wind patterns affecting ice flow …

Ecological, Climatic, And Geomorphic Controls Of The Transport And Fate Of Co2 In Coastal Arctic Aquatic Ecosystems, Alina Spera

Open Access Theses & Dissertations

Due to the ecological and physical responses of arctic tundra to warming, organic carbon (C) stored in frozen permafrost soils is increasingly at risk of mineralization and export to aquatic systems, the coast, and atmosphere. Although many coastal aquatic systems in the Arctic are likely net sources of CO2 to the atmosphere, little is known about the drivers of inorganic C flux and how these systems contribute to regional C budgets. This dissertation addresses several lapses in our understanding of coastal inorganic C dynamics in arctic Alaska via three data chapters. In chapter 2, I examine seasonal and regional variability …

Home Care Work Of Caregivers For Mexican American Adults With Dementia: A Culturally Informed Model Integrating Work System Analyses And Health Disparities Research Framework, Laura Cristina Tovar Felix

Open Access Theses & Dissertations

Dementia is an umbrella term for different diseases such as Alzheimer's, vascular dementia, Lewy body, frontotemporal, and mixed dementias. Dementia is caused by a variety of diseases that cause damage to brain cells interfering with the ability of brain cells to communicate between each other. Dementia is associated with different types of brain cell damage in a specific region of the brain (What Is Dementia?, 2024).Dementia affects 55 million people worldwide, where the most affected population is the low-income and the middle-income countries. (Greenblat, 2023). Every 20 years the number almost double, and by 2039 is estimated to reach 78 …

Investigating Styles Of Contraction And Overprinting By Rio Grande Rift Extension In The Southern Indio Mountains, Western Texas, David W. West

Open Access Theses & Dissertations

Laramide-style intracontinental deformation occurred throughout a large area in the western United States from the late Cretaceous through the Eocene. This event is largely investigated and viewed from classic exposures in Colorado and Wyoming, extending south to southern New Mexico. In this region the Laramide orogen merges with the Mexican fold and thrust belt (MFTB) and the northern limits of the Mexican orogen along a blurry boundary. In the Indio Mountain range in western Texas, Cretaceous sediments were deposited in the Jurassic-Cretaceous Chihuahua trough. They were inverted due to contraction and emplaced adjacent to the Diablo Plateau. This region lies …