Digital Commons Network^™

Expandable Tissue-Engineered Living Surgical Pulmonary Heart Valve For Pediatric Patients, Jacob M. Lautenschlager

All Theses

Cardiovascular disease is the most common cause of mortality in developed countries, with 607.74 million cases globally in 2020.^1,2 Advances in medicine have changed the current demographic suffering from heart valve disease into an aging population suffering from degenerative heart valve disease, creating a growing population treated by surgical or transcatheter intervention.^3-6 Current treatments of valvular heart disease are therefore directed toward valve replacements for the adult population, leaving a treatment gap for pediatric patients suffering from heart valve disease.^7-10

Congenital heart defects are defined as structural abnormalities of the heart or intrathoracic great vessels and are …

Regulation Of Serpina1 Mrna Expression By Environmental Conditions In Hepatocyte Cells, Fnu Jiamutai

All Theses

The SERPINA1 gene encodes the critical protease inhibitor α-1-antitrypsin (A1AT). A1AT represses neutrophil elastase activity to protect lung tissue from inflammatory damage. A deficiency in α-1-antitrypsin can lead to chronic obstructive pulmonary disease (COPD). Pathogenic genetic variants in SERPINA1 are also associated with A1AT protein misfolding and liver cirrhosis. The regulatory mechanisms of SERPINA1 expression are not well understood, but previous studies suggest that alternative polyadenylation in the 3' untranslated region (3'UTR) affects A1AT protein expression. In this study, we used the liver cancer cell line HepG2 to determine how environmental conditions influence SERPINA1 mRNA expression and post-transcriptional regulation. We …

Training Uav Teams With Multi-Agent Reinforcement Learning Towards Fully 3d Autonomous Wildfire Response, Bryce Hopkins

All Theses

As climate-exacerbated wildfires increasingly threaten landscapes and communities, there is an urgent and pressing need for sophisticated fire management technologies. Coordinated teams of Unmanned Aerial Vehicles (UAVs) present a promising solution for detection, assessment, and even incipient-stage suppression – especially when integrated into a multi-layered approach with other recent wildfire management technologies such as geostationary/polar-orbiting satellites and CCTV detection networks. However, there remains significant challenges in developing the necessary sensing, navigation, coordination, and communication subsystems that enable intelligent UAV teams. Further, federal regulations governing UAV deployment and autonomy pose constraints on real-world aerial testing, creating a disconnect between theoretical research …

A Southern War On Predators: How Bounty Laws, Environment, European Thought, And Wolves And Other Predators Influenced Colonial South Carolina, Andrew J. Hubbard

All Theses

During the colonization of South Carolina, the natural landscape was altered significantly by European colonists. Bounty laws targeting the native predatory species were one-way humans facilitated this change. These bounty laws were created and enforced throughout much of the colonial period in South Carolina and permanently removed most of the region’s natural large predators. This thesis contends that South Carolina’s laws tell a story unique among colonial bounty laws provide a unique perspective on Euro-American attitudes toward predators, creating precedents later used in the United States’ westward expansion and war on predators. European bias and stereotypes permeate South Carolina’s culture …

Impact Of Nitrogen Species On Algal Carbon Capture, Lauren J. Todd

All Theses

Increasing global carbon emissions from fossil fuel combustion and the resulting detrimental effects of climate change have created a need for atmospheric carbon drawdown. Biological-based carbon capture not only sequesters carbon dioxide (CO₂) but also provides a sustainable source of biomass for biofuels and biomaterials. Thus, the aim of this research was to examine freshwater green algal growth with total ammoniacal nitrogen (TAN) and nitrate nitrogen (NO₃-N) sources at high pH for improving carbon capture potential. The following objectives were accomplished: nitrogen uptake was identified as simultaneous or sequential, the effect of TAN and NO_{3 …}

Proportioning And Performance Of Ultra-High Performance Concrete (Uhpc) For High Friction Surface Treatment (Hfst) On Pavement And Bridge Decks, Adam R. Biehl

All Theses

High Friction Surface Treatment (HFST) is a roadway remediation technique used to improve pavement’s coefficient of friction, to enhance roadway safety. The application of HFSTs has repeatedly demonstrated the ability to significantly reduce crashes in both wet and dry conditions. Typically, epoxy-resins and calcined bauxite aggregate are used in HFST treatment. However, the high material costs and scarcity of calcined bauxite render this form of HFST an expensive and limited option for roadway rehabilitation. Therefore, the identification of alternative binders and HFST aggregates is needed for broad scale implementation. One potential alternative binder is Ultra-High-Performance Concrete (UHPC), a specialty cementitious …

Hydrogen Isotope Exchange On Diffusion Pump Oils, Carson G. Allen

All Theses

The extent of isotopic exchange of deuterium and tritium with protium atoms in hydrocarbon pump oil was investigated as a means to quantify the chemical stability of a mineral oil, a silicone oil, and a polyphenyl ether oil as candidates for implementation in a diffusion pump. In its target application at a fusion power plant, a chemically stable and radiation hard oil offers substantial reductions in tritium inventory, electrical consumption, and operational pump expenses over alternate solutions for vacuum induction. Select oils were introduced to deuterium and tritium isotopes in a high temperature environment, analogous to an operating vacuum pump. …

Advancing Unmanned Ground Vehicle Path Planning With Quantified Map Uncertainty, Israel Afriyie

All Theses

This thesis addresses the complex challenge of path planning for Unmanned Ground Vehicles (UGVs) in areas where traditional navigation systems are inadequate, such as unstructured or off-road military zones. Recognizing the limitations of current path planning algorithms, which primarily focus on optimizing for the shortest path and often fail to account for variability and risks, this research proposes an enhanced Hyperstar algorithm. This approach not only considers the fastest route but also integrates maximum delays and visibility risks into its computation, ensuring a balance between swift mission completion and concealment from adversaries.

Utilizing terrain maps and incorporating uncertainties in map …

Learning From Burning: Connecting Fire Managers And Fire Scientists, Coleman Lloyd Little

All Theses

The fire community is one of transparency and learning, and embedded in its culture is an openness of sharing successes and failures in order to learn and adapt. United by a shared desire to effectively understand and utilize controlled burns to successfully extinguish wildfires and research their lasting effects, fire managers and fire scientists coexist in partnerships commonly referred to as knowledge exchange networks. This research examines one such network, the Consortium of Appalachian Fire Managers and Scientists (CAFMS), through the experiences of some of its members, serving to develop an understanding of how the consortium functions as a knowledge …

Effects Of The Sea Level Rise And Hurricanes In The Coastal Forest Of South Carolina, Siddhartha Regmi

All Theses

Accessing the mortality of the trees following any disturbances is of great interest to researchers in forestry science. This thesis project assessed topographic factors to explain the patterns of tree mortality after Hurricane Hugo in 1989 and investigated continuous tree mortality in relationship to important covariates using long-term data. Aerial photographs were taken one year after Hurricane Hugo, and long-term monitoring plots were set up five years after the hurricane to collect multi-year data. Analysis and visualization showed higher mortality in concave areas near the marsh at approximately 1-2m elevation and 120-180m far from streams after Hurricane Hugo. A model …

Investigations Of Sulfurized Polymers For Their Use In Lithium-Sulfur Cells, Alan M. Rowland

All Theses

With the invention of the Lithium-Ion cell in the latter half of the 20th century, there has been a continued endeavor for innovation in compact energy-storage. Combined with the ever-growing need to move away from fossil fuels, electrochemical energy storage has seen a myriad of research projects in the pursuit of finding the ‘beyond-lithium’ cell. One of these projects that I personally assisted with was lithium-sulfur cells, which allow for a significantly greater energy storage capacity when compared to lithium-ion cells. In investigating a popular cathode in lithium-sulfur cells, sulfurized polyacrylonitrile (SPAN), it was hinted that there may be more …

Unraveling Wetland Ecology: The Effect Of Abiotic Heterogeneity And Habitat Size On Wetland Plant Diversity In The Piedmont, Gregory T. Gilmore

All Theses

Ecosystems around the world are seeing an unprecedented decline in biodiversity. However, to better prevent this decline we cannot only understand the drivers of biodiversity loss, but also the factors that support diversity. Traditional ecological hypotheses such as the Habitat Heterogeneity Hypothesis (HHH) and the Theory of Island Biogeography (TIB) have provided frameworks for understanding biodiversity drivers. However, recent research suggests a more nuanced relationship between heterogeneity, habitat size, and diversity than previously thought. This study looks to bridge existing research gaps by examining the ecologically and conservational important habitat of wetlands. Specifically, the study focuses on the plant diversity …

A Study On Physical And Digital Art Intergration Workflows, David Miller

All Theses

This MFA thesis explores the intricate interplay between physical and digital realms within the realm of artistic creation. The investigation delves into three distinct tasks, each serving as a unique facet of the overarching theme. Firstly, a physical snake sculpture crafted from clay becomes the focal point of a transition from the tangible to the digital through the innovative process of photo scanning within a light sphere. This transformative journey from the physical to the digital realm unveils the potential for seamless integration between traditional and contemporary artistic mediums. The second task involves the creation of a digital character meticulously …

University Of Tennessee At Chattanooga Faculty Handbook, 2024 August 1, University Of Tennessee At Chattanooga. Office Of Academic Affairs, University Of Tennessee At Chattanooga. Faculty Senate

University of Tennessee at Chattanooga Faculty Handbooks

Governance, policies, guidelines, services, and resources managed by and for the faculty at the University of Tennessee at Chattanooga.

August 2024, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

National Immunization Awareness Month

Each year, thousands of adults in the United States get sick from diseases that could have been prevented by vaccines.

Climate Allocation Compass, A Framework For Real-World Decarbonization (Compass-Frwd), Perrine Toledano, Ajay S. Jagdish, Maria Diez Andres, Ana M. Camelo Vega, Rob Furdak, Christina Bastin, Matt Goldklang, Jane Smyth

Columbia Center on Sustainable Investment

Climate finance currently falls far short of what's required to achieve net-zero targets. In a collaboration with the Man Group, we offer a framework setting out how investors can help to close this gap.

Key takeaways:

1. To address the global climate finance gap,CCSI and Man Group have developed the Climate Allocation Compass, a Framework for Real-World Decarbonization (‘Compass-FRWD’).
2. Compass-FRWD is a six-step asset allocation framework designed to guide strategic capital investment across multiple portfolios. It does so by setting financing targets relative to real-world emission gaps, thereby prioritizing sectors and geographies according to decarbonization needs.
3. Compass-FRWD provides a cyclical, investor-level …

The Confessional Side Of Lennon: Comparing The Lyrics Of John Lennon To The School Of Confessional Poetry, Brandon H. Job

English Theses

Abstract of Thesis

The Confessional Side of Lennon: Comparing the Lyrics of John Lennon to the School of Confessional Poetry

It has been noted by avid listeners, critics, and scholars of Beatles material that John Lennon’s lyrical voice differed from his bandmates. Words such as “somber,” “autobiographical,” “introspective,” “angry,” “dark,” and so on, have all been used to describe his lyrical voice. However, their evaluation ends there without further investigation into his song lyrics’ uniqueness. My study aims to extend the research done on Lennon in order to define the unique voice he used throughout his songwriting career by arguing …

The Health Belief Model And Phishing: Determinants Of Preventative Security Behaviors, Jie Du, Andrew Kalafut, Gregory Schymik

Open Access Publishing Support Funded Articles

Email is frequently the attack vector of choice for hackers and is a large concern for campus IT organizations. This paper attempts to gain insight into what drives the email security behaviors of students, faculty, and staff at one midwestern public, master’s granting university. The survey relies on the health belief model as its theoretical basis and measures eight constructs including email security behavior, perceived barriers to practice, self-efficacy, cues to action, prior security experience, perceived vulnerability, perceived benefits, and perceived severity. Barriers to practice, self-efficacy, vulnerability, benefits, and prior experience variables were found to be significant determinants of self-reported …

Validation Of Scores From A Telephone Administered Multiple Sclerosis Walking Scale-12 In Persons With Multiple Sclerosis, Robert W. Motl, Prudence Plummer, Deborah Backus, Jeffrey R. Hebert, Whitney N. Neal, Alexander V. Ng, John Lowman, Francois Bethoux, Hollie Schmidt, Robert Mcburney, Kevin K. Mccully, Gary R. Cutter

Exercise Science Faculty Research and Publications

Background

The Multiple Sclerosis Walking Scale-12 (MSWS-12) has typically been delivered through paper-and-pencil or computer-based administration.

Purpose

This study examined the validity of inferences from scores derived via a telephone administration of the MSWS-12 applied as part of screening of participants with walking dysfunction into a clinical trial of exercise training in MS.

Method

The MSWS-12 was administered on two occasions separated by approximately 2 weeks through the telephone and then in-person (i.e., computer-based administration). Participants further completed the Patient Determined Disease Steps (PDDS) scale, timed 25-foot walk (T25FW), six-minute walk (6MW), Modified Fatigue Impact Scale (MFIS), and Multiple Sclerosis …

A Brief Values-Based Intervention For Increasing Distress Tolerance In Overcontrol, Katherine Hyde Brott

Graduate Theses and Dissertations

Overcontrol is a transdiagnostic personality syndrome underlying difficult-to-treat psychopathology. Current treatments options are limited, and those that do exist are both cost- and time-prohibitive. Brief interventions are one pathway to improving the care of people with overcontrol. This study had two major aims: (1) evaluate a brief values-based intervention to increase distress tolerance in people with overcontrol and (2) examine the correlates of overcontrol using a novel, theoretically derived transdiagnostic measure of overcontrol. Participants (n = 177) were randomly assigned to one of three conditions: values clarification only, linking values to emotion, or a control condition. They then completed a …

How Supply Chains Respond To Disruptions: Three Essays On Responses To Operational, Geopolitical, And Natural Disaster Disruptions, Travis Kulpa

Graduate Theses and Dissertations

The ability to respond to supply chain disruptions efficiently and effectively is a highly sought after capability, particularly in light of recent events such as the COVID-19 pandemic, geopolitical conflicts, and major natural disasters. These events have led researchers, practitioners, and policymakers to ask: how can we better use our resources to respond to supply chain disruptions? This dissertation examines responses to the three main types of supply chain disruptions: operational disruptions, geopolitical disruptions, and natural disasters. The first study examines how US importers adjust between air and containerized transportation in response to shipment delays and abnormally high demand from …

Proton-Coupled Electron Transfer To Drive Biomass Conversion, Cody Canote

Graduate Theses and Dissertations

Meeting rising demands for commodity chemicals while simultaneously easing reliance on fossil fuels presents one of the most substantial challenges for chemistry to date. Biomass has emerged as a sustainable precursor to commodity chemicals but requires substantial deoxygenation to displace petrochemicals. Development of efficient catalysts to achieve these transformations remains one of the central goals of inorganic and organometallic chemistry. Electrochemical strategies to propel biomass conversion are attractive, providing the driving force for reactivity and insights into catalyst mechanism. This work focuses on proton-coupled electron transfer (PCET) to facilitate redox catalysis in biomass up conversion and homolytic bond cleavage in …

Modeling, Optimization, And Characterization For Choke Horn Antennas, Ibrahim Nasser I Alquaydheb

Graduate Theses and Dissertations

This dissertation presents a comprehensive study focusing on the modeling, optimization, and characterization of choke horn antennas (CHAs). An analytical model designed to capture the parameters of CHA and derive the total radiated fields from the choke and waveguide elements is primarily focused on in this work. Compared to the use of simulation software, such as ANSYS HFSS (High Frequency Structure Simulator) or CST Studio, which employs numerical methods to simulate and calculate antenna performance, numerous advantages are offered by the analytical model. Analytical models provide deeper insight into electromagnetic interactions and the principles governing antenna behavior, leading to a …

Rock Wall Fracturing As A Potential Control On River Valley Width In The Buffalo National River, Arkansas, Kindle Hon

Graduate Theses and Dissertations

Quantifying bedrock properties that control the persistence of fallen rock material (talus) along bedrock walls bounding river valleys may be a key factor in understanding what controls the rate at which these river valleys widen. My work is a component of a collaborative research project focused on the overarching hypothesis that the persistence vs. erodibility of talus that buffers river valley walls can be a first-order control on valley widening rates. I hypothesize that the primary control for creating erodible or persistent talus is the fracture spacing of bedrock valley walls as it sets the maximum block size of collapsed …

Effects Of Measurement Error In Student Pre-Post Test Score On The Recovery Of The Estimates Of Teachers Value-Added Scores, Merlin J. Kamgue

Graduate Theses and Dissertations

Abstract Background: Value-added models (VAMs) are statistical tools used to gauge a teacher’s impact on student performance by analyzing standardized test scores. These models project students’ future performance based on past scores and compare the projection to actual outcomes, accounting for differences in student backgrounds. However, the standard error of measurement (SEM) inherent in all measurement tools is often overlooked in VAMs. Aims and Objectives: This study aims to investigate the impact of test reliability on teacher and school score estimates within a Bayesian framework. We will precisely manipulate the reliability of standardized tests by adjusting the standard error of …

Tissue Engineered Models Of Environmental And Metabolism-Driven Cancer-Nerve Crosstalk, Emory Gregory

Graduate Theses and Dissertations

Purpose: Within the last 30 years, cancer-nerve interactions have garnered attention for causing patient pain, increasing the risk of recurrence, and decreasing patient prognosis. There are 2 key forms cancer-nerve crosstalk takes: perineural invasion (PNI), in which cancer cells infiltrate nerves as a route for metastasis, and tumor innervation (TI), in which neurites penetrate solid tumors to promote tumor progression. Present in vitro models of cancer-nerve crosstalk primarily include Matrigel® mouse matrix and collagen I hydrogels; whereas collagen I hydrogels neglect tumor extracellular matrix (ECM) complexity, Matrigel® is controversial for its batch-to-batch inconsistencies and inclusion of experiment-altering growth factors. Decellularized …

Approaches To Controlling Palmer Amaranth And Its Interference In Furrow-Irrigated Rice, Tanner Austin King

Graduate Theses and Dissertations

Palmer amaranth (Amaranthus palmeri S. Wats) is the most troublesome and problematic weed in most mid-southern U.S. row crop production systems. With the increased adoption of furrow-irrigated rice (Oryza sativa L.), there is a greater occurrence of Palmer amaranth due to sustained moist conditions allowing continual emergence of the weed throughout the growing season. Palmer amaranth has previously been shown to negatively affect crop yields when left unmanaged. Therefore, there is a high potential for rice yield loss due to the weed’s ability to emerge over an extended period and interfere with crop development. However, there is a lack of …

Remodel-Fpga: Reconfigurable Memory-Centric Array Processor Architecture For Deep-Learning Acceleration On Fpga, Md Arafat Kabir

Graduate Theses and Dissertations

Deep-Learning has become a dominant computing paradigm across a broad range of application domains. Different architectures of Deep-Networks like CNN, MLP, and RNN have emerged as the prominent machine-learning approaches for today’s application domains. These architectures are heavily data-dependent, requiring frequent access to memory. As a result, these applications suffer the most from the memory bottleneck of the von Neumann architectures. There is an imminent need for memory-centric architectures for deep-learning and big-data analytic applications that are memory intensive. Modern Field Programmable Gate Arrays (FPGAs) are ideal programmable substrates for creating customized Processor in/near Memory (PIM) accelerators. Modern FPGAs contain …

Environments And Controls Of Erosional Bedforms In Soluble Channels, Ethan W. Oleson

Graduate Theses and Dissertations

Erosional bedforms, such as scallops, preserve valuable information on the paleohydrologic conditions forming soluble channels in karst systems. While these bedforms are commonly used to interpret past conditions, questions about their formation remain. Mathematical models of speleogenesis in turbulent flow predict that the conditions for forming scallops do not occur in natural carbonate systems. However, scallops are readily found in caves throughout the world. This conundrum has several possible resolutions, but each lacks field-based observations. We present a field-based study of the environments and controls of scallops in gypsum, limestone, and dolostone caves. Our results are based on field observation, …

Understanding The Emergence Of Self-Determination In Children With Disabilities Through Family Experiences In Early Childhood: A Qualitative Study, Karen K. Lange

Graduate Theses and Dissertations

Abstract A person’s ability to be self-determined begins to develop through the earliest interactions in life within the context of the family and caregiving environments. This qualitative phenomenological study of the experiences of eight parents representing seven families of young children explored how families promote their children’s early development of the skills, abilities, and attitudes of self-determination. The critical importance of the family context for the promotion of self-determination in young children is seen in the four themes that emerged from the experiences shared by these families. (1) The family context is transformed by a child with a disability, changing …