Digital Commons Network^™

Inhibitory Activities Of Phytoconstituents From Azadirachta Indica And Murraya Koenigii As Potential Drugs For Secondary Infection Of Atopic Eczema Disease - In Silico Study, Mikidadi S. Gurisha, Pulapa V. Kanaka Rao, Laxmikanth Cherupally

Tanzania Journal of Science

Atopic Eczema (AE) disease is a chronic inflammatory skin condition that is caused by a person’s inability to repair damage to the skin barrier. Staphylococcus aureus (SA) is a virulent pathogen that plays an important role in the progression of secondary infection in AE patients, thus intensifying the disease's virulence. In this study, the inhibitory activities of phytoconstituents from Azadirachta indica and Murraya koenigii against the SA (Protein Data Bank ID: 7TIO) using an in silico approach are presented. Site-specific docking analysis was carried out on the virulent pathogen with the docking center at X: 1.65044, Y: 1.7980, Z: 3.1878, …

Trust And Reliability Of Information Sources On Facebook For Presidential Candidates: A Study Of Voter Perceptions, Kristina Harrison, Shawn Thelen, Boonghee Yoo

Journal of Applied Marketing Theory

This exploratory research, utilizing both open-ended and likert-type questions, identifies who voters trust on Facebook for information about Presidential candidates as well as the benefits of using Facebook for obtaining this information. In line with Social Identity Theory, results indicate that some sources, especially those that are respected/intimate are far more trusted than others, e.g., local media, national media, and celebrities. Findings indicate that voters, drawn from a national online sample, enjoy the social aspects of connecting with like-minded individuals, use it to source information about candidates, find the platform convenient, but express some concerns over the reliability of information …

Impact Of Pegylated Liposomes On Cytotoxicity Of Tamoxifen And Piperine On Mcf-7 Human Breast Carcinoma Cells, Klaudi K. Vaiphei, A Prabakaran, Singh Snigdha, Satyajit Laxman Murkute, Purusottam Mohapatra, Rakesh Kumar Sahoo, Sanya Batheja, Umesh Gupta, Anu Puri, Upal Roy

Health & Biomedical Sciences Faculty Publications

Tamoxifen (TMF) is an anticancer agent used for managing estrogen receptor-positive breast cancer. It has limited therapeutic efficacy against breast cancer, which could be enhanced by the coadministration of herbal drugs like piperine (PIP). However, the hydrophobic nature of TMF and PIP restricts their therapeutic application. Therefore, the present study focuses on the impact of the anticancer activity of TMF in combination with PIP and after entrapping them into liposomes (TMF-PIP-LPs and TMF-PIP-PEG-LPs). The liposomes were prepared using the thin film hydration method. In addition, the morphology of the prepared liposomes was found spherical after SEM and TEM analyses. Further, …

Smile! You’Re On Camera: Police Use Of Automatic License Plate Readers And The Need For Statewide Legislation, Cailyn Hoang

University of Dayton Law Review

No abstract provided.

“Standing” In The Way Of Equality: Acheson Hotels, Llc, V. Laufer, Hayley R. Mullen

University of Dayton Law Review

No abstract provided.

Public Health Emergencies And The Second Amendment, Amy Swearer, Paul J. Larkin

Denver Law Review

For many decades, gun control advocates, hoping to shift the terms of the debate to more favorable terrain, have argued that gun violence should be viewed primarily through the lens of public health. In September 2023, New Mexico Governor Michelle Lujan Grisham and New Mexico Secretary of Health Patrick Allen pushed that rationale to its extreme and beyond. Under the auspices of the state’s public health emergency laws, they issued an executive order and agency directive that effectively eliminated the right of ordinary citizens to bear arms in public in the state’s most populous county. That attempt to circumvent the …

Victim Impact Statements In Mass Tort Bankruptcy Cases: Balancing Chapter 11'S Proceduralism With Tort Law's Commitment To Nonmonetary Recovery, Julia Boccagno

Denver Law Review

Bankruptcy has evolved into tortfeasors’ choice of law for resolving mass tort litigation. The United States Bankruptcy Code is equipped with procedural devices designed to maximize litigants’ financial recovery and enhance judicial efficiency. Although bankruptcy procedures aim to resolve widespread liability and open the courthouse doors to litigants who may not otherwise recover, they simultaneously overlook the nonmonetary and dignitary objectives underlying tort law. This Note uses the Supreme Court’s recent decision in Harrington v. Purdue Pharma—a high-profile example of mass tort litigation resolved through bankruptcy—to examine the extent to which bankruptcy procedures are unable to fulfill the nonmonetary objectives …

"Recognize Me As Who I Am": Names, Pronouns, And The Intersection Of Title Vii And Title Ix, Ariell Bachman

Denver Law Review

In 2020, the Supreme Court decided Bostock v. Clayton County, a case about Title VII of the Civil Rights Act of 1964. Bostock interpreted Title VII to prohibit employers from using an employee’s sexual orientation or gender identity in adverse employment decisions. Many federal circuit courts and the U.S. Department of Education (DOE) have used Bostock’s reasoning to conclude that Title IX of the Educational Amendments of 1972 prohibits schools from treating a student adversely based on that student’s sexual orientation or gender identity. However, many states and school districts have mandated the intentional use of the incorrect name and …

Competency Model For General Managers Of Chain Independent Clinical Laboratory (Icl) Subsidiaries, Haiyan Wen

Dissertations and Theses Collection (Open Access)

An independent clinical laboratory (ICL) is a medical institution that has received approval from health authorities, holds independent legal status, and specializes in medical testing or pathological diagnostics, assuming responsibility independently. It is also referred to as a third-party medical testing laboratory. During in-depth research on the enterprises, it was found that while the chain ICL industry is rapidly growing, the issues of uncertainty and difficulty in selecting subsidiary general managers have become a common concern and pain point among senior managers.

The study combines theoretical and data analysis to identify distinct and important competency characteristics of general managers of …

Impact Of Project Simulation Shareholding Incentive On Team Performance: Research Based On The Construction Industry, Jian Zhou

Dissertations and Theses Collection (Open Access)

China's construction industry is vast and possesses a wide market; however, it faces challenges such as unclear stratification and low concentration levels. Construction enterprises face significant constraints in key areas such as financial strength, team stability, and technological advancement, while also bearing substantial costs related to supervision and accountability. The project simulation shareholding mode enhances employees' sense of belonging and responsibility through a collaborative approach characterized by joint management, shared risks, and shared benefits. This improves project execution efficiency and quality, ultimately strengthening the core competitiveness of the enterprise. In the construction industry, projects often involve substantial investments and long-term …

Correlation And Causation Analysis For Cross-Sectional And Panel Data, Barry Nuqoba

Dissertations and Theses Collection (Open Access)

This dissertation investigates how data, algorithms, and expert knowledge can be harnessed to better understand human behavior and enhance well-being. It emphasizes the critical importance of interdisciplinary collaboration to bridge knowledge gaps and foster insights that support preventive care, causal theory advancement, and policy development.

The first study, part of the SHINESeniors project, shed light on the potential usefulness of passive, unobtrusive sensors for detecting nocturia and poor sleep quality, symptoms commonly observed in chronic diseases, thereby enabling live-alone older adults to age in place. Utilizing machine learning techniques on sensor-derived features, the study can identify nocturia and poor sleep …

Causality Analysis For Neural Network Security, Bing Sun

Dissertations and Theses Collection (Open Access)

While neural networks are demonstrating excellent performance in a wide range of applications, there has been a growing concern on their reliability and dependability.Similar to traditional decision-making programs, neural networks inevitably have defects that need to be identified and mitigated at times. Neural networks are usually inherently black-boxes and do not provide explanations on how and why decisions are made. As a result, these defects are more ``hidden" and more challenging to eliminate. It is thus crucial to develop systematic approaches to identify and mitigate defects in a neural network in a rigorous way.

In this dissertation, we focus on …

Robust Learning With Probabilistic Relaxation Using Hypothesis-Test-Based Sampling, Zilin Wang

Dissertations and Theses Collection (Open Access)

In recent years, deep learning has been a vital tool in various tasks. The performance of a neural network is usually evaluated by empirical risk minimization. However, robustness issues have gained great concern which can be fatal in safety-critical applications. Adversarial training can mitigate the issue by minimizing the loss of worst-case perturbations of data. It is effective in improving the robustness of the model, but it is too conservative, and the plain performance of the model can be unsatisfying. Probabilistic Robust Learning (PRL) empirically balances the average- and worst-case performance while the robustness of the model is not provable …

Towards Robust, Secure, And Privacy-Aware Large Language Models Of Code, Zhou Yang

Dissertations and Theses Collection (Open Access)

The field of software engineering has witnessed a surge in large language models specifically tailored to understand and process code, which we call large language models for code (LLM4Code). The increasing popularity of LLM4Code is inseparable from three key factors: the availability of extensive datasets compiled from diverse data sources, the advancements in deep learning algorithms and computational power that facilitate the training of these powerful models, and the active engagement and collaboration within the research community fostering innovation and the rapid exchange of ideas and methodologies. As evidenced by a series of studies, LLM4Code has been experiencing rapid development …

Manufacturing Enterprises' Gross Margins And Performance: A Study On The Moderating Effect Of Management Expenses And R&D Expenses, Jiuliu Zhang

Dissertations and Theses Collection (Open Access)

In the context of globalization, manufacturing enterprises are integral to national economies, with their financial stability closely related to increasingly fierce market competition. Among various financial metrics, gross margin stands out as a key indicator of product profitability, significantly impacting production decisions, cost control, and pricing strategies. Understanding the relationship between the gross margins of manufacturing enterprises and their performance is essential for optimizing their financial structures and enhancing their market competitiveness. The study aims to investigate the correlation between gross margin and enterprise performance by developing complex, scientifically sound models and utilizing big data analysis technology. Additionally, it examines …

A General Model For The Ductility Of Intermetallics Applied To Fe-Co Alloys, Wesley Everhart, Joseph Newkirk

Materials Science and Engineering Faculty Research & Creative Works

The mechanical properties, specifically ductility, of high performing soft magnets such as Fe-Co alloys are a limiting factor to their broader use in a number of systems. The understanding of the mechanical robustness in these materials is currently insufficient to be able to support the growing interest in applications such as magnetic shielding or electric motors. Fe-Co alloys provide the highest commercially available magnetic saturation and high magnetic permeability but have very poor ductility. The addition of vanadium to these alloys has allowed for significant commercialization and some ductility improvements, but the fundamental reasons for the observed improvements are not …

They Never Left: Drivers Of Memory Of Dictatorship And Impressions Of Ferdinand E. Marcos As President After February 1986, Jorge V. Tigno, Geoffrey M. Ducanes, Steven Rood, Vladymir Joseph A. Licudine

Economics Department Faculty Publications

Between 1972 and 1986, Ferdinand E. Marcos of the Philippines headed an autocratic system that allowed him to rule with little to no accountability. Some 36 years after FM (as he is popularly called) and family were driven from power into exile in Hawaii, his son, Ferdinand ‘Bongbong’ Marcos, Jr., was overwhelmingly elected President in the May 2022 general elections. This turnaround seemed puzzling to many, but others saw a long-term deliberate process of rehabilitation after the family returned to the Philippines. Our paper explores how Filipinos remembered FM in the years after his ouster. What drives the memory of …

Observation Of Dense Collisional Soliton Complexes In A Two-Component Bose-Einstein Condensate, Sean M. Mossman, Garyfallia C. Katsimiga, Simeon I. Mistakidis, Alejandro Romero-Ros, Thomas M. Bersano, Peter Schmelcher, Panayotis G. Kevrekidis, Peter Engels

Physics Faculty Research & Creative Works

Solitons Are Nonlinear Solitary Waves Which Maintain their Shape over Time and through Collisions, Occurring in a Variety of Nonlinear Media from Plasmas to Optics. We Present an Experimental and Theoretical Study of Hydrodynamic Phenomena in a Two-Component Atomic Bose-Einstein Condensate Where a Soliton Array Emerges from the Imprinting of a Periodic Spin Pattern by a Microwave Pulse-Based Winding Technique. We Observe the Ensuing Dynamics Which Include Shape Deformations, the Emergence of Dark-Antidark Solitons, Apparent Spatial Frequency Tripling, and Decay and Revival of Contrast Related to Soliton Collisions. for the Densest Arrays, We Obtain Soliton Complexes Where Solitons Undergo Continued …

Publisher Correction: Observation Of Dense Collisional Soliton Complexes In A Two-Component Bose-Einstein Condensate (Communications Physics, (2024), 7, 1, (163), 10.1038/S42005-024-01659-W), Sean M. Mossman, Garyfallia C. Katsimiga, Simeon I. Mistakidis, Alejandro Romero-Ros, Thomas M. Bersano, Peter Schmelcher, Panayotis G. Kevrekidis, Peter Engels

Physics Faculty Research & Creative Works

In the first paragraph of the Methods section, the sentence "We begin with an elongated BEC of approximately 9 x 10587Rb atoms…," has erroneously been written without a space between the two superscripts "5" and "87". This has now been corrected in both the HTML and PDF of the article, and the same expression reads: We begin with an elongated BEC of approximately 9 x 105 87Rb atoms…"

Author Correction: Dual Nature Of Magnetism Driven By Momentum Dependent F-D Kondo Hybridization (Communications Physics, (2024), 7, 1, (186), 10.1038/S42005-024-01631-8), Byungkyun Kang, Yongbin Lee, Liqin Ke, Hyunsoo Kim, Myoung Hwan Kim, Chul Hong Park

Physics Faculty Research & Creative Works

Correction to: Communications Physicshttps://doi.org/10.1038/s42005-024-01631-8, published online 12 June 2024 In this article the grant number DE-AC02-07CH11358 relating to Ames National Laboratory was omitted. The original article has been corrected.

Publisher Correction: Observation Of Dense Collisional Soliton Complexes In A Two-Component Bose-Einstein Condensate (Communications Physics, (2024), 7, 1, (163), 10.1038/S42005-024-01659-W), Sean M. Mossman, Garyfallia C. Katsimiga, Simeon I. Mistakidis, Alejandro Romero-Ros, Thomas M. Bersano, Peter Schmelcher, Panayotis G. Kevrekidis, Peter Engels

Physics Faculty Research & Creative Works

In the first paragraph of the Methods section, the sentence "We begin with an elongated BEC of approximately 9 x 10587Rb atoms…," has erroneously been written without a space between the two superscripts "5" and "87". This has now been corrected in both the HTML and PDF of the article, and the same expression reads: We begin with an elongated BEC of approximately 9 x 105 87Rb atoms…"

Density Effects On The Interferometry Of Efimov States By Modulating Magnetic Fields, G. Bougas, S. I. Mistakidis, P. Giannakeas

Physics Faculty Research & Creative Works

Dynamical association of Efimov trimers in thermal gases by means of modulated magnetic fields has proven very fruitful in determining the binding energy of trimers. The latter was extracted from the number of remaining atoms, which featured oscillatory fringes stemming from the superposition of trimers with atom-dimers. Subsequent theoretical investigations utilizing the time-dependent three-body problem revealed additional association mechanisms, manifested as superpositions of the Efimov state with the trap states and the latter with atom-dimers. The three atoms were initialized in a way to emulate a thermal gas with uniform density. Here, this analysis is extended by taking into account …

Multiphoton-Dressed Rydberg Excitations In A Microwave Cavity With Ultracold Rb Atoms, J. D.Massayuki Kondo, Seth T. Rittenhouse, Daniel Varela Magalhaes, Vasil Rokaj, S. I. Mistakidis, H. R. Sadeghpour, Luis Gustavo Marcassa

Physics Faculty Research & Creative Works

We investigate magneto-optical trap-loss spectroscopy of Rydberg excited Rb85 (66≤n≤68S1/2) atoms, placed inside a tailored microwave cavity. The cavity frequency at 13.053 GHz is in resonance with the 67S1/2→66P3/2 transition, inducing a ladder multiphoton microwave Rydberg absorption and emission. The observed spectra are modeled with an extended Jaynes-Cummings formalism that accounts for nonlinear multiphoton absorption from and emission into the cavity, the loss from the trap due to Rydberg excitation, and cavity imperfection. We calculate the average photons in each spectral feature and find evidence for fractional photon emission into the cavity modes within the loss spectra. The microwave cavity …

Nodal Superconductivity In Miassite Rh17s15, Hyunsoo Kim, Makariy A. Tanatar, Marcin Kończykowski, Romain Grasset, Udhara S. Kaluarachchi, Serafim Teknowijoyo, Kyuil Cho, Aashish Sapkota, John M. Wilde, Matthew J. Krogstad, Sergey L. Bud'ko, Philip M.R. Brydon, Paul C. Canfield, Ruslan Prozorov

Physics Faculty Research & Creative Works

Solid state chemistry has produced a plethora of materials with properties not found in nature. For example, high-temperature superconductivity in cuprates is drastically different from the superconductivity of naturally occurring metals and alloys and is frequently referred to as unconventional. Unconventional superconductivity is also found in other synthetic compounds, such as iron-based and heavy-fermion superconductors. Here, we report compelling evidence of unconventional nodal superconductivity in synthetic samples of Rh₁₇S₁₅ (Tc = 5.4 K), which is also found in nature as the mineral miassite. We investigated the temperature-dependent variation of the London penetration depth Δλ(T) and the disorder …

The Provision Of Healthcare For Older Adults In A Massachusetts Jail/House Of Correction: Perspectives From Providers, Laura Driscoll

Graduate Doctoral Dissertations

THE PROVISION OF HEALTHCARE FOR OLDER ADULTS IN A MASSACHUSETTS JAIL/HOUSE OF CORRECTION: PERSPECTIVES FROM PROVIDERS November 2024 Laura C. Driscoll, B.S., Boston University M.S.P.T., Boston University DPT, MGH Institute of Health Professions M.S., University of Massachusetts Boston Ph.D., University of Massachusetts Boston Directed by Professor Jan Mutchler The aging population in U.S. jails is growing rapidly presenting significant challenges for healthcare provision within carceral settings. Older adults in these facilities often experience complex health conditions, including chronic diseases and age-related impairments, that require specialized care. Despite this, limited research has explored the experiences of healthcare providers tasked with caring …

The Application Of High-Resolution Mass Spectrometry For The Analysis Of Biopolymers, Metabolites, And Biologically Relevant Small Molecules, Christ Duc Tran

Graduate Doctoral Dissertations

High-resolution mass spectrometry (HRMS), as its name suggests, possesses high resolving power that enables the separation of ions with very close mass values. This is particularly beneficial for analyzing complex samples where numerous compounds may have similar masses, as it helps prevent signal overlaps and ensures an accurate spectral analysis. The current work explores the diverse applications of high-resolution mass spectrometry in oligonucleotide research, organic synthesis and medicinal chemistry. Oligonucleotide research: Chapters 2-5 present the research results from studies that employed ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-HRMS) to understand the pharmacokinetics of RNA interference (RNAi) therapeutics. The …

Predicting Newborn Low Birth Weight: A Machine Learning Approach Using Maternal Health And Demographic Data, Rayan Elsayed

Theses

Low birth weight (LBW), defined by the World Health Organization as a birth weight under 2500 grams, remains a major global health challenge due to its association with increased risks for adverse neonatal and long-term health outcomes. This study aims to identify maternal health factors that contribute to LBW and to develop predictive models to support early identification of at-risk pregnancies. Two machine learning models, Logistic Regression (LR) and Random Forest (RF), were developed to analyze the relationship between maternal factors and LBW outcomes. The RF model achieved an accuracy of 96.36%, demonstrating robust predictive performance across metrics, making it …

Tehran Is Ours, Hamideh Azimi

Theses

Tehran is Ours is a thesis film, mainly 2D animation, with some experimental and 3D parts. This film dramatizing the movement that is happening in Iran which is about women’s rights. 2D fluid animation represents the movement that never stops.

Recast, Reform, Reshape: Surreal Figurative Painting, Keely Wu

Theses

This thesis explores the use of surreal imagery and the reimagining of historical subjects as a means to discuss complex ideas of identity. In this exploration, I chose to use the human figure as a vessel for expressing my own intimate viewpoints and experiences. Through a series of paintings, I investigate how the juxtaposition of human forms with non-human elements challenges conventional notions of gender and sexuality to empower marginalized perspectives. My Master’s degree started with my transition from commercial illustration to fine art. The study examines my evolution of thematic and stylistic choices, emphasizing the creation of new works …

Smart Credit Card Fraud Detection Using Machine Learning, Aisha Bin Sulaiman, Rowdha Masood Falaknaz

Theses

This thesis addresses the increasing issue of fraud resulting from technological advancements affecting both customers and fraudsters, while law enforcement agencies face challenges of inadequate case prioritization; data overload and slow investigative analysis. The central objective of this thesis revolves around strategies to counter these challenges, emphasizing the urgency of rapid response to major alert cases that can lead to widespread impacts. The authors' experience in financial fraud detection and credit card crime investigation within the police department has inspired this research, guiding the approach toward practical solutions for everyday operational challenges. The significance of this thesis lies in its …