Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 119401 - 119430 of 1826819

Full-Text Articles in Entire DC Network

Construction Site Planning And Logistical Operations: Site-Focused Management For Builders, Second Edition, Randy R. Rapp, Bradley L. Benhart Dec 2024

Construction Site Planning And Logistical Operations: Site-Focused Management For Builders, Second Edition, Randy R. Rapp, Bradley L. Benhart

Purdue Handbooks in Building Construction

Organizing and administering a construction site so that the right resources get to the right place in a timely fashion demands strong leadership and a well-defined, disciplined process. Good logistical operations enable profitability, and this book is the essential, muddy boots guide to such management. Written by experienced educator–practitioners, Construction Site Planning and Logistical Operations is a popular guide to the knowledge, skills, and abilities needed by project superintendents, especially, but useful to all constructors. This second edition is updated to include new technologies, resources, and details of operational planning. Leadership imperatives and management techniques remain integrated throughout. The book …


Testing Vivo-Morpholino Mediated Gene Knockdown Of Stat6, Spi1b, And Hnf4Α In Adult Threespine Stickleback, Stella Dipippo Dec 2024

Testing Vivo-Morpholino Mediated Gene Knockdown Of Stat6, Spi1b, And Hnf4Α In Adult Threespine Stickleback, Stella Dipippo

Honors Scholar Theses

The fibrotic immune response to the cestode parasite, Schistocephalus solidus, varies among threespine stickleback populations. Fibrosis suppresses parasite growth but has costly effects on the fish. Previous genomic studies in stickleback have suggested potential roles of Spi1b, STAT6, and HNF4α in modulating fibrosis severity, but there is presently no evidence for this in-vivo. We used antisense vivo-morpholino oligonucleotides (MOs) to attempt to knockdown the expression of each gene in the liver, spleen, and intestine of adult stickleback. Vivo-MOs have been proven effective in other species of teleost fish, as well as in mice and humans, but …


Non-Conformity As Queerness: The Phenomenology Of Gender Identity Beyond The Binary, Gretl Josselyn Dec 2024

Non-Conformity As Queerness: The Phenomenology Of Gender Identity Beyond The Binary, Gretl Josselyn

Honors Scholar Theses

Gender non-conformity is a defiance of fixed binary ideas of gender identity and expression which are enforced within societies. The phenomenological concept of breaking free from expectations based on one’s gender assigned at birth allows freedom of expression and an acceptance of non-conformity. Building on the works of Judith Butler, Sara Ahmed, María Lugones, and Iria Marion Young, among others, the act of performance and queering one’s identity and actions are explored. Gender identity is constantly evolving, and each expectation of what one’s gender expression should look like is a performance put on to conform. Individuals are not born with …


Converting Lignocellulosic Biomass Into Valuable End Products For Decentralized Energy Solutions: A Comprehensive Overview, Ahmed Aboulmagd Dr., Ahmad Mustafa, Shah Faisal, Jaswinder Singh, Boutaina Rezki, Karan Kumar, Vijayanand Moholkar, Ozben Kutlu, Hamdy Thabet, Zeinhom El-Bahy, Oguzhan Der, Cassamo Mussagy, Luigi Di Bitonto, Mushtaq Ahmad, Carlo Pastore Dec 2024

Converting Lignocellulosic Biomass Into Valuable End Products For Decentralized Energy Solutions: A Comprehensive Overview, Ahmed Aboulmagd Dr., Ahmad Mustafa, Shah Faisal, Jaswinder Singh, Boutaina Rezki, Karan Kumar, Vijayanand Moholkar, Ozben Kutlu, Hamdy Thabet, Zeinhom El-Bahy, Oguzhan Der, Cassamo Mussagy, Luigi Di Bitonto, Mushtaq Ahmad, Carlo Pastore

Renewable Mechanical Energy

This review manuscript delves into lignocellulosic biomass (LCB) as a sustainable energy source, addressing the global demand for renewable alternatives amidst increasing oil and gas consumption and solid waste production. LCB, consisting of lignin, cellulose, and hemicellulose, is versatile for biochemical and thermochemical conversions like anaerobic digestion, fermentation, gasification, and pyrolysis. Recent advancements have led to a 25 % increase in bioethanol yields through alkali pre-treatment and optimized fermentation, a 20 % enhancement in microbial delignification efficiency, and a 35 % improvement in enzyme efficiency via nanobiotechnology. These innovations enhance biofuel production sustainability and cost-effectiveness. Decentralized energy systems utilizing locally …


Mechanical Engineering Insights : Highlights From Final Year Projects 2024 Dec 2024

Mechanical Engineering Insights : Highlights From Final Year Projects 2024

Research Publications (2021 to 2025)

Mechanical Engineering Insights: Highlights from Final Year Project 2024” features a carefully curated collection of outstanding Final Year Projects from the graduating students from the Mechanical Engineering Department, Faculty of Engineering, Universiti Malaya. These projects showcase what the students can achieve after four years of hard work and learning. Each project reflects their creativity and technical skills, showing how they can solve real world problems with practical and sustainable solutions. This compilation is divided into three fundamental themes: Mechanical, Manufacturing, and Materials, representing the core domains of mechanical engineering. The Mechanical theme showcases our students' prowess in applying theoretical knowledge …


The Role Of Nutrient Solutions On Phosphate-Solubilizing Bacteria Population, Phosphorus Availability, Phosphorus Uptake, Growth And Yield Of Red Chili (Capsicum Annuum L.), Betty Natalie Fitriatin, Raden Faqih Hilmiy Ghifari, Emma Trinurani Sofyan, Fitri Widiantini, Hanif Fakhrurroja, Tualar Simarmata Dec 2024

The Role Of Nutrient Solutions On Phosphate-Solubilizing Bacteria Population, Phosphorus Availability, Phosphorus Uptake, Growth And Yield Of Red Chili (Capsicum Annuum L.), Betty Natalie Fitriatin, Raden Faqih Hilmiy Ghifari, Emma Trinurani Sofyan, Fitri Widiantini, Hanif Fakhrurroja, Tualar Simarmata

Jurnal Kultivasi

Red chili consumption in Indonesia has increased every year. However, with large chili production to meet large consumption, land conversion for various purposes has reduced the harvested area. The efforts to increase the harvested area of chili using Inceptisols soil by providing nutrient solutions to overcome the infertility of the soil using its nutrients. This experiment aims to determine the effect of nutrient solution application on the population of phosphate-solubilizing bacteria, phosphorus availability, phosphorus uptake, growth, and yield of Red Chili (Capsicum annuum L.) in Inceptisols. The experiment was conducted from August 2023 to February 2024 at Ciparanje Experimental Field, …


Impacts Of Gibberellin Application On Citrus: An Overview From Seed Germination To Fruit Quality Enhancement, Siti Auliya Rahma, Rahmat Budiarto, Syariful Mubarok, Supatida Abdullakasim Dec 2024

Impacts Of Gibberellin Application On Citrus: An Overview From Seed Germination To Fruit Quality Enhancement, Siti Auliya Rahma, Rahmat Budiarto, Syariful Mubarok, Supatida Abdullakasim

Jurnal Kultivasi

Gibberellins are key plant hormones, and their application in citrus plants is frequently reported. This review aims to provide an overview of the application of gibberellic acid (GA3) in citrus cultivation, emphasizing their effects on growth, flowering, fruit quality, and ripening. Citrus fruits often face challenges like irregular fruit set, size inconsistency, and environmental stress, impacting yield and profitability, with exogenous gibberellin application as a potential solution. Applying gibberellins can accelerate citrus seed germination and seedling growth, enhance vegetative growth, inhibit flowering, delay fruit ripening, and improve fruit quality. However, the efficacy of gibberellins varies across species and conditions, highlighting …


Working Paper No. 92, Karl Polanyi, Human Labor, And The Working Class, Niccolo Cellini Dec 2024

Working Paper No. 92, Karl Polanyi, Human Labor, And The Working Class, Niccolo Cellini

Working Papers in Economics

This inquiry seeks to establish that Karl Polanyi advanced ideas regarding human labor that we could judge as both seminal and enduring. Through examining his famous book, The Great Transformation, we could draw out three interconnected theses central to his critique of market-oriented economies. Firstly, we could emphasize that Polanyi judges labor as a fictitious commodity, emphasizing distinct aspects associable with labor’s emergence during the industrialization of England. In developing his ideas Polanyi draws upon the historical examples of the Speenhamland System and Frederick Engels' accounts of industrial labor that highlighted the destabilizing effects of embedding labor within …


Going Generic: A Linguistics Approach To Genericide In Trademark Law, James A. Heilpern, William G. Eggington, Earl Kjar Brown, Zachary D. Smith Dec 2024

Going Generic: A Linguistics Approach To Genericide In Trademark Law, James A. Heilpern, William G. Eggington, Earl Kjar Brown, Zachary D. Smith

BYU Law Review

This Article examines the phenomenon of trademark genericide—the process by which once-protected brand names like “escalator” and “trampoline” lose their legal status by becoming synonymous with entire product categories. Traditional methods used by courts to assess genericide, such as consumer surveys and dictionary definitions, are often criticized for their subjectivity and lack of scientific rigor. In response, this Article introduces corpus linguistics as a more reliable, data-driven alternative for determining whether a trademark has become generic.

By analyzing real-world language usage through large corpora, corpus linguistics can track the public’s shifting perceptions of a trademark over time. Using case studies …


Corpus Linguistics At The U.S. Patent And Trademark Office, Tabrez Y. Ebrahim Dec 2024

Corpus Linguistics At The U.S. Patent And Trademark Office, Tabrez Y. Ebrahim

BYU Law Review

This Article examines the intersection of corpus linguistics and patent law. It introduces the foundations of corpus linguistics and its application to the law and advances the potential for its application to patent examination at the United States Patent and Trademark Office (USPTO). Historically, the disciplines of corpus linguistics and patent law did not intersect until scholars began to consider the application of corpus linguistics to patent litigation for interpretation of terms in patent claims. Interpretation of legal language provided by corpus linguistics and applied to patent examination at the USPTO has yet to be addressed and is a novel …


Simulation Studies Of Mvdc Power Cable For All Electric Aircrafts, Aban Samimi Motlagh Dec 2024

Simulation Studies Of Mvdc Power Cable For All Electric Aircrafts, Aban Samimi Motlagh

Electrical and Computer Engineering ETDs

MVCD power cable has a vital task in future commercial electric aircraft, which is power delivery. The temperature of the cable during the cable’s operation under low pressure is higher than the atmospheric pressure, which increases the cable losses. In this paper, the temperature and electric field across the insulator of the 5 kV DC Southwire cable is simulated up to 10 hours of cable operation. Furthermore, the temperature of the cable is shown with and without the presence of the chamber box. The other issue of the MVDC power cable is the cable joints and terminations. The electric field …


Gpu-Accelerated Community Detection: Performance Comparison Of Networkx And Cugraph, Venkata Satyanarayana Pulaparthi Dec 2024

Gpu-Accelerated Community Detection: Performance Comparison Of Networkx And Cugraph, Venkata Satyanarayana Pulaparthi

Masters Projects

Community detection in complex networks is an essential process in the field of network science, offering insights into the underlying structure and functionality of interconnected systems. As the scale and complexity of networks grows, traditional CPU-based methods for community detection struggle to keep pace, leading to the exploration of GPU-accelerated solutions.

This project investigates the implementation of the Louvain algorithm for community detection using GPU-accelerated computing via the CuGraph library. By comparing it too traditional CPU based methods implemented with NetworkX, this study examines performance improvements, scalability, and applicability across real-world datasets. Two networks were used for experimentation: Zachary’s Karate …


3d Game: Enhancing Game Ai With Machine Learning, Nicholas William English Dec 2024

3d Game: Enhancing Game Ai With Machine Learning, Nicholas William English

Masters Projects

Machine learning (ML) and artificial intelligence (AI) are terms that are often used synonymously, but they are ever-so slightly different. Machine learning is really a subset of artificial intelligence and involves creating an algorithm so that a computer can learn patterns. Artificial intelligence extends machine learning with the goal to go beyond pattern recognition by having a computer that is capable of mimicking human intelligence. Video games often use the term AI in reference to the bots or non-playable characters (NPCs) that players may interact with. Generally, these bots do not actually implement AI, nor do they use ML, but …


Theory And Algorithms To Learn, Propagate, And Exploit Uncertainty For Stochastic Optimal Control Of Dynamical Systems, Vignesh Sivaramakrishnan Dec 2024

Theory And Algorithms To Learn, Propagate, And Exploit Uncertainty For Stochastic Optimal Control Of Dynamical Systems, Vignesh Sivaramakrishnan

Electrical and Computer Engineering ETDs

Non-Gaussian uncertainty frequently arises in learning and control problems involving stochastic dynamical systems, particularly in autonomous vehicles, UAVs, satellites, and robotics. In this dissertation, we propose a new framework that leverages characteristic functions that provides a frequency-domain representation of random variables. The dissertation is structured into three key areas. First, we address model-based stochastic optimal control for linear systems with non-Gaussian noise, demonstrating that characteristic functions can be used to enforce chance constraints and control systems toward desired distributions. Second, we explore data-driven stochastic control, utilizing empirical characteristic functions to handle systems with unknown disturbances. In addition, we derive several …


A Personal Journey Of Self-Reflection, Brooke Heil Dec 2024

A Personal Journey Of Self-Reflection, Brooke Heil

Dissertations, Theses, and Projects

Abstract

In this analysis, I investigate the different layers that make up who I am, exploring my personal experiences, relationships, academic pursuits, career path, mental and physical health, cultural background, coping mechanisms, strengths, and aspirations. Coming from a family deeply impacted by alcoholism, mental health struggles, and loss, I navigate through life's challenges, drawing insights from various psychological theories to understand my own journey. Through self-reflection and insights from those around me, I explore themes of resilience, independence, and how my past shapes my present. This analysis was constructed with personal stories, reflections, and observations, providing a holistic view of …


Effects Of Modification In Limonene And Geraniol On The Properties Of Thermal Cured Polyurethane Films, Sauravkumar Rajeshbhai Patel Dec 2024

Effects Of Modification In Limonene And Geraniol On The Properties Of Thermal Cured Polyurethane Films, Sauravkumar Rajeshbhai Patel

Electronic Theses & Dissertations

The increasing demand for green materials has inspired in-depth research into biobased polymers; among these polymers, polyurethanes stand out because of their widest range of applications: coatings, adhesives, and biomedical devices. The subject of this paper is the preparation of bio-based polyurethane films based on the polyols synthesized from renewable feedstocks such as limonene, geraniol, and soybean oil. Limonene and geraniol were chemically modified from natural sources such as citrus fruits and essential oils to high-functionality polyols. Characterization of such polyols showed that geraniol had the highest hydroxyl (OH) value and thus geraniol-based polyurethane films were highly influencing in reactivity …


Targeting Myeloid Cell Iron Metabolism In Salmonella-Induced Colitis, Mariella Arcos Padilla Dec 2024

Targeting Myeloid Cell Iron Metabolism In Salmonella-Induced Colitis, Mariella Arcos Padilla

Biomedical Engineering ETDs

Salmonellosis is a severe infection caused by Salmonella enterica serovar Typhimurium, leading to significant global morbidity and mortality.

Previous studies have shown that mice lacking the iron storage protein ferritin heavy chain (FTH1) in myeloid cells exhibit worsened Salmonella infection. Nuclear receptor co-activator 4 (NCOA4) directs FTH1 autophagic degradation to release iron from storage during conditions of low iron. However, the role of myeloid NCOA4 in regulating bacterial infections remains unclear.

Here, we found that myeloid NCOA4 deficiency augments spleen iron levels and increases cellular iron accumulation, oxidative stress, and ferroptosis in bone marrow-derived macrophages (BMDM) cells. This deficiency also …


Modern Agricultural Servitude: The Modern Farm Worker Experience In The Salinas Valley, Jesus E. Tavarez Dec 2024

Modern Agricultural Servitude: The Modern Farm Worker Experience In The Salinas Valley, Jesus E. Tavarez

Chicana and Chicano Studies ETDs

The prevailing narrative in Chicanx studies focuses on the historical labor activism of the United Farm Workers (UFW) in the 1960s and ‘70s. I am particularly interested in examining the contemporary campesino experience in the Salinas Valley by discussing the history behind Mexican cheap labor, low wages, exploitive work conditions with inadequate healthcare, agrochemical exposure, and historical consciousness of farm workers. I will argue that farm workers are in dire need of a migratory reform as an approach to improve the working conditions of farm workers throughout California. This research aims to shed light on how the multi-billion-dollar agribusiness industry …


Evaluation Of Electrode Configurations For (0,2) Piezoelectric Ultrasound Transducers, Abdul Qayoum Popal Dec 2024

Evaluation Of Electrode Configurations For (0,2) Piezoelectric Ultrasound Transducers, Abdul Qayoum Popal

Mechanical Engineering ETDs

Piezoelectric micro ultrasound transducers (PMUT array) are pivotal in MEMS applications. They typically operate in the fundamental (0,1) acoustic mode and are not significantly researched for higher modes (0,2) and (0,3). Similarly, vibrating mesh atomizers (VMAs) demand the second (0,2) mode and third mode (0,3) for effective aerosol generation, highlighting the need for optimized electrode configurations—a relatively unexplored area. This study presents the first comprehensive analysis of how electrode designs influence PMUT performance in the (0,2) mode for VMA applications.

Utilizing COMSOL multiphysics finite element modeling (FEM) with residual stress considerations alongside experimental validation, we demonstrate that optimized electrode configurations …


Operations On Submodules With The Multiplicative And Quotient Properties, Jiekai Pang Dec 2024

Operations On Submodules With The Multiplicative And Quotient Properties, Jiekai Pang

Mathematics & Statistics ETDs

Inspired by the works of Petro, Epstein, Vassilev, and Morre, this thesis aims to study the generalized definitions of the semiprime operation, weakly prime operation, and standard closure operation on rings, that is, the multiplicative operation, weakly multiplicative operation, and standardly multiplicative operation on submodules. Then, we will use Matlis duality to induce the dual notions of these definitions on submodules of Matlis-dualizable Artinian modules. In order to understand the dual notion of the standardly multiplicative operation, that is, the standardly quotient operation, we will classify the operations on the injective hull of residue field of the ring K[[x,y]]/(xy) which …


Conceptualization, Measurement, And Contributors To Participation Among People Living With Parkinson’S Disease, Moon Young Kim Dec 2024

Conceptualization, Measurement, And Contributors To Participation Among People Living With Parkinson’S Disease, Moon Young Kim

WUSM Theses and Dissertations – All Programs

Participation is a key outcome of rehabilitation and key to successful aging. Individuals with Parkinson’s disease (PD) often experience significant challenges in maintaining participation in meaningful activities and roles. This dissertation examines the influence of living with PD on participation by integrating findings from three studies: a systematic review, a cross-sectional study, and a longitudinal study.

The systematic review synthesized the existing quantitative research on participation in people with PD, revealing inconsistencies in the conceptualization of participation. While the evaluation tools aimed at assessing participation in PD showed acceptable coverage of domains of participation, the assessment of the aspects of …


Modelling V-Band Atmospheric Loss With Deep Learning, Ralph Lyndon Gesner Dec 2024

Modelling V-Band Atmospheric Loss With Deep Learning, Ralph Lyndon Gesner

Electrical and Computer Engineering ETDs

Modelling atmospheric loss is fundamental to implementation of future mm-wave terrestrial and earth space communication links. Atmospheric losses have traditionally been estimated by calculating the contributions of individual weather phenomena through in-situ meteorological measurements and statistically derived models for estimating localized atmospheric water content. Collecting data for all points along the propagation path and calculating the physical effects of gases, clouds, and precipitation individually is both time consuming and impractical for large-scale use cases.

In response to these present limitations, this work proposes the use of novel deep learning models for estimating atmospheric losses from tabular meteorological sensor data and …


Trastuzumab Deruxtecan With Nivolumab In Her2-Expressing Metastatic Breast Or Urothelial Cancer: Analysis Of The Phase Ib Ds8201-A-U105 Study., E Hamilton, Galsky Md, S Ochsenreither, Conte G Del, M Martín, De Miguel Mj, Yu Ey, Anja Williams, M Gion, Tan Ar, L Agrawal, A Rutten, Machiels Jp, S Hurvitz, Philip Debruyne Dec 2024

Trastuzumab Deruxtecan With Nivolumab In Her2-Expressing Metastatic Breast Or Urothelial Cancer: Analysis Of The Phase Ib Ds8201-A-U105 Study., E Hamilton, Galsky Md, S Ochsenreither, Conte G Del, M Martín, De Miguel Mj, Yu Ey, Anja Williams, M Gion, Tan Ar, L Agrawal, A Rutten, Machiels Jp, S Hurvitz, Philip Debruyne

School of Nursing and Midwifery

Purpose:This multicenter phase Ib study investigated trastuzumab deruxtecan (T-DXd) plus nivolumab in patients with HER2-expressing metastatic breast cancer (mBC) and metastatic urothelial cancer (mUC).Patients and Methods:Part 1 determined the recommended dose for expansion of T-DXd plus nivolumab. Part 2 evaluated efficacy and safety; the primary endpoint was confirmed objective response rate by independent central review.Results:In part 1, seven patients with mBC were enrolled and received T-DXd 3.2 mg/kg (four patients) or 5.4 mg/kg (three patients) plus nivolumab. The recommended dose for expansion for T-DXd was 5.4 mg/kg plus nivolumab 360 mg intravenously every 3 weeks. In part 2, 32 patients …


Top Ten Epilepsy Research Priorities: A Uk Priority Setting Partnership, Rohit Shankar Dec 2024

Top Ten Epilepsy Research Priorities: A Uk Priority Setting Partnership, Rohit Shankar

Peninsula Medical School

Purpose: Research into epilepsy has experienced decades of chronic underfunding compared to other neurological conditions despite its prevalence and seriousness. To evidence the need for greater investment, the Epilepsy Research Institute (formerly Epilepsy Research UK) funded, led and managed a James Lind Alliance (JLA) Priority Setting Partnership (PSP). This “industry standard” methodology brings together healthcare professionals, patients, carers and patient group representatives to identify and prioritise research uncertainties within a defined area of health or care.Methods: The UK Epilepsy PSP is a once-in-a-generation, national consensus that collated and ranked the research priorities of the UK epilepsy and associated condition community. …


An Energy Resource Management For Cluster Based Iohv Supported By Fog Computing, Ahmed Jawad Kadhim Dec 2024

An Energy Resource Management For Cluster Based Iohv Supported By Fog Computing, Ahmed Jawad Kadhim

Karbala International Journal of Modern Science

Internet of Hybrid Vehicle Networks (IoHV) is a network generated by merging the Internet with a Hybrid Vehicular Ad-Hoc Network (H-VANET). In IoHV, various types of electric and fuel vehicles create tasks. However, executing several tasks by electric vehicles affects their lifetime because they suffer from energy limitation issues which is one of the IoHV challenges. On the other hand, fuel vehicles and fog nodes have unlimited energy and can be used to execute most tasks of electric vehicles quickly. In this paper, we produce a new Energy Resource management Technique for IoHV called ERTH that aims to offload the …


Effect Of Temperature And Rhenium Content In Precipitates On Dispersion Hardening Of Tungsten, Yulia R. Sharapova, Arseny M. Kazakov, Elena A. Korznikova, Alexandr Zinovev, Dmitry Terentyev, Sergey V. Dmitriev Dec 2024

Effect Of Temperature And Rhenium Content In Precipitates On Dispersion Hardening Of Tungsten, Yulia R. Sharapova, Arseny M. Kazakov, Elena A. Korznikova, Alexandr Zinovev, Dmitry Terentyev, Sergey V. Dmitriev

Karbala International Journal of Modern Science

Tungsten (W) is being developed as a plasma-facing material for fusion reactors, where it is subjected to MeV neutron irradiation, low-energy helium isotope particles, and high temperatures. These conditions lead to the formation of point defects, dislocation loops, voids, and transmutation into rhenium (Re) and osmium (Os), which form precipitates that significantly impact dislocation motion and increase hardness. This study uses molecular dynamics modeling to examine the interaction between an edge dislocation and Re-rich particles of various stoichiometries, specifically coherent bcc-phase particles and noncoherent σ-phase precipitates. Results show that shear stress increases by approximately 20-40% with larger particle size (3-5 …


Gauss-Lobatto Method For Nuclear Reactivity Calculation, Daniel Suescún-Díaz, Luis E. Cardoso-Páez, Diego Peña-Lara Dec 2024

Gauss-Lobatto Method For Nuclear Reactivity Calculation, Daniel Suescún-Díaz, Luis E. Cardoso-Páez, Diego Peña-Lara

Karbala International Journal of Modern Science

In this paper, we introduce a novel approach to numerical solving for nuclear reactivity using the inverse equation of point kinetics as a model. Our method leverages the Gauss-Lobatto quadrature, incorporating multiple time steps and nodes derived from Legendre polynomials of varying orders. To enhance the accuracy of the differential component of the inverse equation, we employed a differential scheme based on the Gauss-Lobatto quadrature nodes. To address fluctuations in neutron population density, we implemented a second-order low-pass Butterworth filter with a minimal window length of M = 3 samples. Through extensive numerical simulations, we assessed the precision of our …


Aromatic Compounds And Organic Acids Identified From Ganoderma Formosanum Exhibit Synergistic Anti-Melanogenic Effects, Chen-Che Hsieh, Chih-Yao Hou, Hsiao-Yun Lei, Darin Khumsupan, Huey-Jine Chai, Pek-Kui Lim, Cheng-Chih Hsu, Sz-Jie Wu, Kai-Wen Cheng, Yi-Chen Chen, Kuan-Chen Cheng Dec 2024

Aromatic Compounds And Organic Acids Identified From Ganoderma Formosanum Exhibit Synergistic Anti-Melanogenic Effects, Chen-Che Hsieh, Chih-Yao Hou, Hsiao-Yun Lei, Darin Khumsupan, Huey-Jine Chai, Pek-Kui Lim, Cheng-Chih Hsu, Sz-Jie Wu, Kai-Wen Cheng, Yi-Chen Chen, Kuan-Chen Cheng

Journal of Food and Drug Analysis

This study reveals the anti-tyrosinase activity of Ganoderma formosanum extracts, pinpointing compounds including gluconic acid, mesalamine, L-pyroglutamic acid, esculetin, 5-hydroxyindole, and salicylic acid, as effective melanin production inhibitors in melanoma cells and zebrafish embryos. Furthermore, multiple molecular docking simulations provided insights into interactions between the identified compounds and tyrosinase, increasing binding affinity up to -16.36 kcal/mol. The enhanced binding of identified compounds to tyrosinase facilitated synergistic inhibitory effects on melanin production. This study highlights the potential of GFE-EA as a source of natural tyrosinase inhibitors and contributes to understanding the role of active compounds extracted from G. formosanum.


Herbal Nanoemulsions In Cosmetic Science: A Comprehensive Review Of Design, Preparation, Formulation, And Characterization, Benni Iskandar, Ta-Wei Liu, Hui-Ching Mei, I-Chih Kuo, Meircurius Dwi Condro Surboyo, Hsiu-Mei Lin, Ching-Kuo Lee Dec 2024

Herbal Nanoemulsions In Cosmetic Science: A Comprehensive Review Of Design, Preparation, Formulation, And Characterization, Benni Iskandar, Ta-Wei Liu, Hui-Ching Mei, I-Chih Kuo, Meircurius Dwi Condro Surboyo, Hsiu-Mei Lin, Ching-Kuo Lee

Journal of Food and Drug Analysis

The rapid development of delivery systems for cosmetics has revealed two critical challenges in the field: enhancing the solubility of active ingredients and ensuring the stability of natural materials used in cosmetics. Nanoemulsion technology has emerged as an indispensable solution for addressing these challenges, not only enhancing the stability of cosmetics but also improving the solubility of pharmaceuticals and active ingredients with poor solubility. Nanoemulsion formulations have reinforced stability and amended the bioavailability of hydrophobic drugs. Moreover, nanoemulsion exhibit excellent skin penetration and long-lasting effects, making them particularly appealing to consumers, especially in the cosmetic industry. This article aims to …


Therapeutic Approach Of Carbon Nanotube: Revolutionize Nanomaterial In Biomedical And Pharmaceutical Sector, Shovan Ghosh, Vivek Dave, Pranay Wal Dec 2024

Therapeutic Approach Of Carbon Nanotube: Revolutionize Nanomaterial In Biomedical And Pharmaceutical Sector, Shovan Ghosh, Vivek Dave, Pranay Wal

Journal of Food and Drug Analysis

Carbon nanotubes (CNTs) has emerged as a promising nanomaterial with a wide range of potential applications due to their unique structural, mechanical, electrical, and thermal properties. However, numerous obstacles must be overcome for CNTs to be used successfully, including low solubility, aggregation, and a lack of specialized functions. Diverse techniques have been developed for the manufacture, purification, and functionalization of CNTs in order to overcome these issues. The main aim of this review article is to provide brief knowledge about CNTs and strategies to use this revolutionized nanomaterial in drug delivery. Prepare CNTs cannot be directly used as drug carrier …