Digital Commons Network^™

The Effect Of Cyp1a2 Gene Polymorphisms On Caffeine Pharmacokinetics And Exercise Performance In Male Recreational Athletes, Chloe Masters, Ajmol Ali, Claire Badenhorst, Martin Dickens, Kay Rutherfurd-Markwick

Research outputs 2022 to 2026

This study examined the effects of caffeine consumption on endurance exercise performance, and the influence of CYP1A2 gene polymorphisms in caffeine pharmacokinetics and exercise performance. The data sets of two randomised, double blind, placebo-controlled crossover study design experiments have been merged. Thirty-eight recreationally active male participants provided saliva samples for CYP1A2 genotyping (AA homozygotes n = 19; AC heterozygotes n = 19) and completed either a 10-km run or 40-km cycling time trial of 60-min following a single dose of 6 mg·kg⁻¹ caffeine (CAF) or placebo (maltodextrin; PLA) throughout which heart rate (HR) and time to completion (TTC) were …

Muscle–Tumor Crosstalk In Exercise Oncology: Exercise-Induced Myokines And Cancer Cachexia, Amirhossein Ahmadi Hekmatikar, Francesco Bettariga, Álvaro López Llorente, Diego Fernández-Lázaro, Katsuhiko Suzuki, D. Maryama Awang Daud

Research outputs 2022 to 2026

Exercise-induced myokines, such as IL-6, irisin, and myostatin, play crucial roles in mediating systemic adaptations and modulating tumor progression. This narrative review synthesizes evidence on how regular moderate-intensity exercise affects the myokine network within the tumor microenvironment (TME) of solid tumors. Results from the 86 included studies indicate that structured training (aerobic: 45–65% VO2 max; resistance: 45–70% 1RM) enhances the expression of beneficial myokines that support immune surveillance, reduce inflammation, and improve muscle–tumor cross-talk. IL-6 demonstrates a dual modulatory effect on inflammation and immunity; irisin contributes to tumor apoptosis, while myostatin downregulation supports muscle integrity and metabolic balance. Evidence suggests …

The Moderating Effect Of Dietary Fiber And Protein On The Relationship Between Symptoms Of Depression And Anxiety And Cognitive Decline, Samantha L. Gardener, Hilal Salim Said Al Shamsi, Stephanie R. Rainey-Smith, Hamid R. Sohrabi, Kevin Taddei, Colin L. Masters, Ralph N. Martins, W. M.A.D. Binosha Fernando

Research outputs 2022 to 2026

Introduction: Depression and anxiety often co-occur with Alzheimer's disease, exacerbating the associated cognitive impairment. This study examined moderating effects of dietary protein and fiber intake on relationships between depressive and anxiety symptoms, and cognitive decline.

Methods: Cognitively unimpaired (n = 553; 39.4% male, 70.6 ± 9.6 years) provided baseline fiber and protein intake, and had repeated cognitive testing and symptoms of depression/anxiety measured (baseline and up to eight follow-ups over 144 months). Moderation and simple slope analyses were employed in the cohort as a whole and following stratification by sex.

Results: Fiber intake moderated the relationship between change in depressive …

Advancing Dimensional Models Of Psychopathology In Cancer: Insights From Applying The Hierarchical Taxonomy Of Psychopathology (Hitop), Darren Haywood, Jai Carmichael, Miriam K. Forbes, Roman Kotov, Robert F. Krueger, Aidan G.C. Wright, Susan L. Rossell, David Castle, Wendy Lam, Maryam Lustberg, Colin E. Vize, Anna Ugalde, Phyllis Butow, Nicolas H. Hart

Research outputs 2022 to 2026

Objective: Cancer survivors, defined as those living with or beyond a cancer diagnosis, experience more than double the prevalence of psychopathology when compared to the general population. Categorical diagnostic systems, such as the Diagnostic and Statistical Manual of Mental Disorders (DSM), remain dominant in psycho-oncology despite concerns about reliability, validity, and clinical utility for this population. Dimensional frameworks, such as the Hierarchical Taxonomy of Psychopathology (HiTOP), offer a more precise alternative; however, they have not yet been widely applied in cancer survivors. Accordingly, the objective of this research was to examine the applicability of HiTOP to cancer survivors. Methods: Data …

Does Poor Regulation Lead To Pollution? Key Takeaways From A Systematic Review, Vincent Emenyonu, Kat O. Mara, Mark Lund

Research outputs 2022 to 2026

Formal recycling of used lead acid batteries (ULAB) is a multibillion-dollar industry, valued at US$12.12 billion in 2024, and expected to grow to more than $26 billion within eight years. Demand for recycled lead (Pb) for new batteries grows in developing countries where costs limit the uptake of lithium-ion batteries. ULAB recycling in these regions poses significant danger to human health and the environment. Stringent regulatory approaches for ULAB recycling in developing countries, intended to reduce pollution, have thus far been ineffective as they typically do not adequately cover small-scale informal recycling in rural and remote communities. We examine what …

Integrative Oncology For Prostate Cancer: A Narrative Review, Kevin T. Liou, Nicole A. Metri, Robert U. Newton, Divya Ajay, Eleanor M. Walker, Channing J. Paller

Research outputs 2022 to 2026

Prostate cancer is most common malignancy among men in the United States. As men are now living longer with prostate cancer due to advances in treatment, there exists a growing need to manage the long-term physical and psychological sequelae of this disease, which range from genitourinary dysfunction to cardiometabolic and psychosocial consequences. Over half of men with prostate cancer report unmet needs in symptom management. Integrative oncology, a patient-centered, evidence-informed field combining lifestyle, natural product, and mind–body interventions with conventional treatments, offers a promising approach to prostate cancer symptom management. This review summarizes the current landscape of integrative oncology research …

Semantic Context Improvisational Retrieval-Augmented Generation For Empathic Conversational Ai, Sharjeel Tahir, Judith Johnson, Jumana Abu-Khalaf, Syed Afaq Ali Shah

Research outputs 2022 to 2026

A fundamental limitation of modern conversational AI is its limited capacity to demonstrate sustained empathy in long-form interactions. We propose SCIRAG (Semantic Context Improvisational Retrieval-Augmented Generation), a feedback-driven retrieval framework for adaptive empathic dialogue. It employs a dual-loop retrieval framework, iteratively optimizing a static counseling dataset through user metadata and feedback memory refinement. To enhance contextual alignment, we deploy retrieval adaptation, enabling the model to retain and leverage past conversational cues based on user preferences. When integrated with Mixtral-8x7B, SCIRAG improves human-rated empathic understanding by +1.26 points and empathic response by +1.00 point on the RoPE scale, while increasing acceptability …

A Remarkable Diversity Of Syngnathid Fishes In A Highly Modified Large Coastal Embayment In The Southeastern Indian Ocean, Glenn I. Moore, Jenelle A. Ritchie, Georgia M. Nester, Glenn A. Hyndes, Alan J. Kendrick

Research outputs 2022 to 2026

Southern Australia supports a high diversity of fishes in the family Syngnathidae, which is recognised as globally threatened, facing threats from coastal development, over-exploitation and bycatch. In southwestern Australia, Cockburn Sound houses a large industrial port and naval defence assets with plans to substantially expand the port facilities but also sits within a recognised syngnathid ‘hotspot’. Using a broad array of data sources, including historical museum vouchers, published records, historical and contemporary observations from notebooks and diving surveys, historical and contemporary trawl surveys, citizen science observations and environmental DNA, we compiled 4839 records of syngnathid fishes from the embayment. Twenty-one …

Dasyurus Hallucatus Movement Response To Fire In A Complex, Resource Rich Tropical Savanna, Ian J. Radford, Annette Cook, Natasha Harrison, Ben Corey, Roberta Bencini, Harriet R. Mills

Research outputs 2022 to 2026

The northern quoll, Dasyurus hallucatus, is part of a suite of threatened native northern Australian mammals that have inappropriate fire regimes listed as a threatening process. However, fire responses reported for D. hallucatus are inconsistent among different studies. Based on the theory that the fire response of D. hallucatus will depend partially on habitat quality, we postulate that home range in high quality savannas of the north Kimberley will be small, post-breeding male mortality low and prey resources little affected by fire. Based on previous research we hypothesised that male D. hallucatus would respond to fire more than females. By …

Forecast: An Exhibition Inviting Slow Feeling Through Participation In Unstable Weather States, Jo Pollitt, Helena Grehan, Lilly Blue, Peggy Attkinson, Justine Dandy, Naomi Joy Godden, Leanda Mason, Renee Esther Newman, Alexa Taylor, Danielle Gilson

Research outputs 2022 to 2026

This paper presents a series of responses from Western Australian based artists and scholars from a range of disciplines including: meteorology, science, education, social work, psychology, art and performance studies, to a year-long exhibition titled Forecast in Gallery 09 at The Art Gallery of Western Australia (AGWA). Forecast is a collaboration between AGWA's Head of Learning and Creativity Research, Lilly Blue, Edith Cowan University's Centre for People, Place and Planet artist-scholar, Jo Pollitt, together with artists Dianne Jones and Eva Fernández. The exhibition invites audiences to contribute to two participatory works: Weather Patterns, a daily changing installation that makes room …

Healthcare Professionals’ Experiences And Perspectives On Self-Management Education For Breast Cancer Survivors In Australian Primary Care: A Qualitative Study, Meng Yuan Li, Tao Wang, Daniel Terry, Haiying Wang, Isabella Zhao, Jing Yu Tan

Research outputs 2022 to 2026

Purpose: Breast cancer has been recognised as a chronic condition, with survivors experiencing long-term physical and psychosocial effects following treatment. Supporting breast cancer survivors to self-manage their health can optimise health-related quality of life and reduce symptom burden. Self-management education (SME) has been advocated at the policy and programme level in Australian primary care, but its uptake is often limited. This study explores healthcare professionals’ (HCPs) experiences and perceptions of SME in primary care, aiming to identify factors influencing its implementation and to support survivorship care for breast cancer survivors in Australia.

Methods: A qualitative descriptive approach was adopted involving …

Rhetorical Physics And The Laws Of Language: A Comparative Analysis Of President Trump And President Macron At The United Nations 2025, David Edmund Allen

Research outputs 2022 to 2026

The paper features a textual analysis of the UN speeches made by the US President Donald Trump and by France’s President Macron. President Trump’s speech was made in the absence of a teleprompter and lasted almost an hour. President Macron’s speech was representative of a more standard diplomatic speech. Both speeches are analyzed using a variety of models and techniques. The analysis incorporates an exploration of Manin’s link of Zipf’s law to concepts from information theory and algorithmic complexity, Tao’s concepts applied to power laws, ‘E pluribus unum’, out of many, one, plus a completely new application of Villermaux’s universal …

Weathering In-Beyond Hydro(S)Cenes, Bronwyn Bailey-Charteris, Kathryn Mcmahon, Mary Christina Rapp, Natalie Davey

Research outputs 2022 to 2026

This paper examines the cultural, ecological and political dimensions of the contemporary water crisis through a curatorial and environmental humanities lens. Through the watery conceptual epoch of the Hydrocene, it highlights the work of artists and interdisciplinary practitioners whose hydro-Artistic methods propose ways to realign human-water relations. Central to this analysis is the role of curatorial care, here understood as a practice of convening, holding and enabling reciprocal encounters between bodies of water, artists and communities. Bringing these diverse practices into dialogue, the paper proposes water not only as subject matter but as a potential collaborator and leaky agent. It …

Fast Online Inference On Semiparametric Models, Xiaohong Chen, Elie Tamer, Qingsong Yao

Cowles Foundation Discussion Papers

This paper develops a framework for fast online inference on semiparametric models with large sample sizes and possibly many covariates. The computational algorithm itself is the object of statistical study: after a globally consistent warm start in the first phase, the path of averaged online iterates generated in the second phase automatically delivers estimators with optimal convergence rates and valid confidence sets. Both phases require only a single pass over the data stream and are well suited to streaming data or to settings with storage/privacy constraints. For semiparametric monotone index models, the averaged trajectory of the second phase lead to …

[5,5]-Fused Anhydride, Thioanhydride, And Imide Derivatives Of Cyclopentadienyl Complexes, Uttam R. Pokharel, Sean Parkin, John P. Selegue

Chemistry Faculty Publications

A new approach to 5,5-fused heterocyclic derivatives of cyclopentadienylmanganese tricarbonyl and pentamethylruthenocene is presented. 1,2-Dicarbophenoxycyclopentadienyl complexes of manganese and ruthenium were hydrolyzed to 1,2-dicarboxylic acids. Oxalyl chloride converted the acids to chlorocarbonyls, which reacted with bis(trimethylsilyl)sulfide to give the cyclopentadienyl-fused thioanhydrides. Alternatively, dehydration of the diacids with trifluoroacetic anhydride closed the diacids to cyclopentadienyl-fused anhydrides. Treatment of the anhydrides with p-toluidine followed by oxalyl chloride led to cyclopentadienyl-fused carboxylic imides. This approach enables direct comparison of electron-deficient Mn(CO)₃ and electron-rich Ru(Cp*) coordination environments on the 5,5-fused heterocycles. Spectroscopic data reveal systematic downfield NMR shifts and higher infrared carbonyl stretching …

A Long Loop, Dan Wessner

GHEA21 Publications

No abstract provided.

Freewrite: Synchronizing Mind, Hand, And Pen – An Excavation Of A Basic Practice, Ibrahim Marazka

GHEA21 Publications

No abstract provided.

The Study Of How Sensory Marketing Techniques Used By Beauty Brands Influence Engagement And Consumer Perception On Social Media Platforms, Particularly By Evoking Specific Consumer Emotions, Eeshani Juthani

Digital Marketing Theses

This study describes how a consumers' attitude towards beauty products on social media is affected by sensory marketing techniques and cues. This study also examines how sensory marketing tactics and elements such as sight, sound, smell, touch, and taste affects the way a consumer engages with content on social media platforms like Tiktok and Instagram.

Preliminary Findings From Intermountain West County Emergency Manager Survey, Bailey Holdaway, Courtney Flint, Gina Gilson, Richard Rushforth

Environment and Society Student Research

In the Intermountain West, water resources and weather conditions are increasingly plagued by uncertainty. Population growth throughout the region may further intensify many of these water-related hazards. County emergency managers are responsible for managing hazards and coordinating interactions among entities at various management levels. They are important entities in efforts to safely and effectively manage water-related hazards in the region.

Pharmed. System Manual: Hololens Application, Eden Woldeselassie

Systems Manuals - 2026

This document provides the full life cycle of PharmEd HoloLens. PharmEd stands for Pharmacy Education. The overall document will go through the complete system manual by going over requirements, followed by design, how to install the application, how to upload the application to Microsoft store, troubleshooting and source code. The first section will explain the background, the existing problems and why the need to develop PharmEd.  Here techniques of requirement gathering and some statistics will elaborated. The following section discusses about functional requirements. The requirement section includes subtopics: functional and nonfunctional requirements for both -programmer and end user- and the …

Robot Remote Control Utility, Jeremy Cantu, Paul Uhlig

Systems Manuals - 2026

The purpose of this document is to describe the Robot Control Management Utility developed in the course of this graduate project. Information included in this document will include the background of the developed product, as well as the functional requirements, data structures, software modules, interface design, installation guide, and sample and troubleshooting guides.

E Classroom+, Ami B. Jariwala

Systems Manuals - 2026

A software platform that enhances many processes correlated with learning is called a learning management system (LMS). It is also known as a management software package that enables the delivery of learning content, resources and activities and also that handles the correlated administration operations. In classrooms, today, teachers, are being commenced with convenience to remodel learning from a traditional transmission model to a student-centered model where students are mostly responsible for their learning. The research conveys that in order to remodel learning, schools require to support a student-centered approach where students can be supported in finding, analyzing, organizing, evaluating, internalizing, …

Kta System Manual, Cayden Garcia

Systems Manuals - 2026

The purpose of this document is to explain the ins and outs of KTA. This includes but not limited to:

- The problem that colleges face when it comes to data analysis and collection

- The history of data analytics at a collegiate level

- Software and hardware requirements for KTA – Developer and User

- The overall design of KTA, how the software is structured and how the stack interacts with one another

- How to install KTA on your machine

- Sample Sessions – including issues that the user may run into and how to fix them

Smart Atm, Majid Hakeem

Systems Manuals - 2026

The Smart ATM is a new system that goal is to create a new experience for ATMs users by creating a different way of using the ATM. It would protect users from germs and bacteria. Instead of using buttons and touch screens, the main input for this system will be the motion sensor. To specify, the system uses Microsoft Kinect, which is the motion sensor for the Xbox One.

This document is a user guide, which is intended to give assistance to users for using the Smart ATM. This document contains an application overview, list of user requirements, the design …

Idioma Tutor, Oralia Mijares

Systems Manuals - 2026

The Idioma Tutor was developed specifically for individuals who desire to learn English through a non-traditional approach, eLearning. Idioma Tutor is an interactive game designed to strengthen individual’s English language adaptation, using an individual-learner approach. The game uses immediate feedback to provide self-analysis for learners. It captivates users and applies best-practices in eLearning and game development to retain and fully engage learners. This system manual outlines provides detailed information for using the Idioma Tutor. This system will be used as a catalyst to support the success of individuals who desire to learn the English language in a fun and interactive …

Solving Rubik's Cube By Using Artificial Intelligence, Polat Coban, Seth Reed

Systems Manuals - 2026

This document will detail a proposal to build a Rubik’s cube simulator, and a Rubik’s cube solver. It is broken into several sections which in turn are broken into subsections.

Data-Driven Characterization Of Counties In The Prison Industrial Complex Using Clustering Analysis, Riley N. Tuccio

Capstone Projects

This project investigates the complex relationship between counties that house prisons in the United States and the rurality associated with them. The central research question explores how both county characteristics, such as variables corresponding to cost of living and demographics of a county, and prison characteristics, such as programming available to inmates and staffing levels, differ across the census-designated rural-urban distinctions. Furthermore, the study examines whether modern data science methods can more accurately define and distinguish these characteristics, providing a nuanced understanding of the Prison Industrial Complex (PIC) and its manifestation across various American communities. The motivation for this research …

Exact X2 Statistic Critical Values For Dice Fairness Testing, Warren Campbell

SEAS Faculty Publications

Two questions were addressed: 1) What are the exact values of the c² statistic critical values? 2. Does a dice tower offer improved fairness of dice rolls?  Critical values of the statistic asymptotically approach those given by the continuous chi-square distribution, but the exact distribution is discrete.  The exact distributions only asymptotically approach the chi-square distribution, and the convergence is slow (1/number of rolls).  Th exact distributions are a function of the number of rolls, the chi-square distribution is not a function of the number of rolls.  Exact values of c² at the 90, 95, and 99 percent …

Reducing Caregiver Burden In Hospice Care, Aubrey Martin Bsn, Rn

Nurse Residency

In family caregivers of adult hospice patient’s, does a nurse-led support program, compared with usual hospice education, reduce caregiver burden?

Building Community Leadership Capacity Through Extension Partnerships: An Evaluation Case Study, Paul A. Hill, Lendel K. Narine

Journal of Human Sciences and Extension

This evaluation study examines the effectiveness of the Leadership Dixie program in enhancing leadership capacity among participants in Washington County, Utah. As a program partner, Utah State University (USU) Extension conducted the evaluation on the program’s 25th class, comprising 27 participants (N = 27). The program, characterized by 10 monthly “Challenge Day” field tours, was evaluated using two instruments to collect data on participant learning and satisfaction levels, overall program experience, demographics, and impacts on social capital, interpersonal leadership skills, community engagement, and volunteerism. Results indicate strong positive outcomes in social capital, community engagement, and volunteerism while highlighting areas for …