Digital Commons Network^™

Increased Dissolution Rate And Decreased Processing Temperature For Immediate Release Fdm 3d Printed Tablet Of Weakly Acidic Drugs By Acid-Base Supersolubilization, Mohammed Irfan Syed

Theses and Dissertations

In recent years, there has been much interest in three-dimensional (3D) printing for the development of personalized and on-demand medications for better therapy. In 3D-printing, materials are deposited layer by layer to form tablets and pellets. Among various 3D-printing technologies, the fused deposition modeling (FDM) 3D printing, where melt-extruded filaments of drug-polymer mixtures are used for 3D printing, is most promising. However, the FDM 3D-printing often produces slow-release tablets that are not suitable for rapid drug action in the body. The present investigation was undertaken to demonstrate how rapidly dissolving 3D-printed tablets of poorly water-soluble acidic drugs could be developed …

Developing Stiripentol Analogs As Potential Ldh Inhibitors For The Treatment Of Glioblastoma, Anshika Y. Jain

Theses and Dissertations

Glioblastoma multiforme (GBM) is a highly proliferative brain tumor that has a 5-year survival rate of ~7 %. Temozolomide (TMZ) is the current standard of care therapeutic for GBM. However, 50% of patients develop resistance to TMZ. Therefore, further investigation for new GBM therapeutics is necessary to overcome this issue of drug resistance. GBM patients are known to overexpress lactate dehydrogenase (LDH), which is inversely correlated with their survival. This key glycolytic enzyme catalyzes the interconversion of pyruvate and lactate and plays an important role in cancer proliferation and invasion. Therefore, we aimed to inhibit LDH for developing therapeutics for …

Modeling Wild Rice Bed Health: A Dual Metric Approach For Bed Strength And Invasive Impact, Seth Sisneros-Martinez

Journal of Earth and Life Science

Wild rice (mannoomin; Zizania palustris) is an aquatic grain that grows in slow-moving rivers and shallow bays throughout northern Minnesota. In Headquarters Bay on Leech Lake, wild rice has served as a cultural staple for Indigenous communities for centuries. However, its population has declined in recent years due to multiple environmental issues. One potential contributor is Eurasian watermilfoil (Myriophyllum spicatum; EWM), an invasive species that forms dense mats capable of outcompeting native aquatic vegetation, including wild rice. EWM was first recorded on the southern shoreline of Leech Lake in 2005 and has since become widespread. This study …

Implementing Rsa Accumulators For Asynchronous And Permissionless Reliable Broadcasting, Eric Webb

CCAC Theses and Dissertations

Asynchronous consensus protocols are essential for decentralized and trustless environments such as decentralized finance (DeFi), supply chain management, and voting systems. These protocols eliminate centralized authority and timing assumptions while improving resilience and security. However, as network sizes increase the communication overhead in these systems becomes a bottleneck that limits scalability and efficiency. One notable example is the Aleph protocol, which stands out as one of the first consensus protocols to be both asynchronous and permissionless while providing Byzantine Fault Tolerance. Unlike many existing asynchronous consensus mechanisms, Aleph is permissionless in nature and does not rely on a trusted dealer …

An Exploration Of Desired Abstinent And Non- Abstinent Recovery Outcomes Among People Who Use Methamphetamine, Alex Elswick, Amanda Fallin-Bennett, Karen L. Roper, Evan Batty, Christopher J. Mclouth, William W. Stoops, Hilary L. Surratt, Carrie B. Oser

UK CARES Faculty Publications

Background In the United States, complete abstinence persists as the standard for demonstrating recovery success from substance use disorders (SUDs), apart from alcohol use disorder (AUD). Although the FDA has recently indicated openness for non-abstinence outcomes as treatment targets, the traditional benchmark of complete abstinence for new medications to treat SUDs remains a hurdle and overshadows other non-abstinent outcomes desired by people with SUDs (e.g., improved sleep, employment, family reunification). This study sought to expand the definition of recovery to include non-abstinent pathways by exploring non-abstinence-based outcomes desired by people who use methamphetamine (PWUM).

Methods Participants (n = 100) were …

Isolated Unilateral Medial Rectus Palsy Due To Acute Pontine Infarction, Miranda Bingham, Shterna Frand, Charley Meadows, Sanjay Sharma

North Texas Research Forum 2025

Isolated unilateral medial rectus palsy is a rare but significant clinical manifestation of acute pontine infarction, often presenting without the typical neurological deficits seen in brainstem strokes. This case report highlights a 61-year-old male with a history of hypertension and diabetes who presented with four days of double vision, with no other significant neurological symptoms such as headache, speech disturbances, or focal weakness. On examination, the patient exhibited an isolated inability to adduct his left eye, without any visual deficits or abnormalities in other cranial nerve functions. Neuroimaging, specifically MRI, confirmed the diagnosis of an acute left pontine infarction. The …

A Swelling Mystery: Hereditary Angioedema In Pregnancy, Karen Valadez-Cuen, Andrea Francis, Alison Rossduetscher, Micheline Tantchou

Central & West Texas and San Antonio GME Research Day 2025

No abstract provided.

Refractory Hydrocephalus Treated With Ventriculo-Cholecystic Shunt In An Adult, Deekshita Valiveti, Munanchu Poudel, Rahul Dadhwal

Gulf Coast Division GME Research Day 2025

No abstract provided.

A Case Of Carcinoma En Cuirasse, Nadeen Gonna, Giancarlo Moscol, Woo Cheal Cho, Constance T. Albarracin, Hung Q. Doan

Gulf Coast Division GME Research Day 2025

No abstract provided.

Duodenorenal Fistula Post-Lithotripsy: A Rare Complication, Anam Zara, Aarohi Parikh, Duyen Quach, Ismail Hader, Georg Elias

Gulf Coast Division GME Research Day 2025

No abstract provided.

Skin Cancer Education For Adolescents: Does Vanity Modify Its Effectiveness?, Erica Ogwumike, Dina Zamil, Harrison Zhu, Shangyi Fu, Emily Powell, Zeena Nawas, Ida Orengo

Gulf Coast Division GME Research Day 2025

No abstract provided.

Todd's Paralysis: Sharpnel-Induce Seizure, Kenny Tran, Alain Folefack

North Texas Research Forum 2025

When evaluating seizure in war veterans, distinguishing new-onset hemiparesis with aphasia from stroke can be challenging due to prior brain injury and anticonvulsant therapy. This case involves a patient with a shrapnel injury displaying stroke-symptoms after a seizure highlights the differences between stroke and seizure-related deficits in this population. Careful consideration of imaging, history and clinical presentation are essential for accurate diagnosis and management.

Gastrografin Enema To The Rescue Of The Glorious Cecal Bascule, Dominique Pean, Bushra Bangash, Guntash Khasria, Ismail Hader

Gulf Coast Division GME Research Day 2025

No abstract provided.

A Rare Case Of Brucellosis Relapse, Rabia Mahfooz, Grant Patterson, Annmary Behanan, Babivigasan Gunasegaran

Gulf Coast Division GME Research Day 2025

No abstract provided.

Recurrent Syncope In A Young Adult With Postural Orthostatictachycardia Syndrome (Pots): A Diagnostic And Therapeutic Challenge, Syed Raza, Shuchita Jhaveri, Neethu George, Julian Nguyen

Gulf Coast Division GME Research Day 2025

No abstract provided.

Fetal Presentation Confirmation On L&D With Ultrasound, Noelle Coen, Aaron Poole

Central & West Texas and San Antonio GME Research Day 2025

No abstract provided.

Incarcerated Gravid Uterus, Adelene Morrow, Aaron Poole

Central & West Texas and San Antonio GME Research Day 2025

No abstract provided.

Media Viability In Resource-Constrained Newsrooms: The Case Of The Observer Newspaper In Uganda, Nakitimbo Amelia Martha

Executive Masters in Media Leadership and Innovation

The Observer newspaper in Uganda has built a solid reputation as an impartial, independent, and analytical publication that adheres to the ethical principles of good journalism. Founded and run by a small team of journalists, the newspaper has weathered many storms, including financial crises, political intimidation, newsroom equipment seizure, and the early death of the vision carrier, Kevin Aliro. This study analyzes and records the approaches used by The Observer's editorial staff to keep the newspaper afloat during two turbulent decades of financial, political, and economic difficulties. In contrast to other newsrooms that are frequently defined by strict hierarchies between …

Evaluating The Viability Of Monetizing Media Content Archives: A Case Of Vision Group, Eva F. Nabagesera Kirunda

Executive Masters in Media Leadership and Innovation

This study examines the viability of a media content archive with a focus on Vision Group. Amid digital transformation, media organizations face mounting pressure to monetize archives of historical, cultural, and journalistic content. This is particularly relevant for legacy media like Vision Group, which confronts external and internal challenges that threaten sustainability. Externally, digital disruption has diminished traditional revenue streams like print advertising and subscriptions, as tech giants dominate digital ad spaces. Younger audiences prefer free, interactive content on social media and podcasts, while inflation and economic pressures shrink advertising budgets and consumer spending. Internally, reliance on outdated business models, …

Employee Engagement In Rebranding, Violet Andoyo Otindo

Executive Masters in Media Leadership and Innovation

Corporate rebranding involves redefining an organization’s mission, vision, and values beyond changes to logos or taglines. Its success depends on active employee engagement, as employees play a critical role as brand ambassadors. The rebranding of the National Syndemic Diseases Control Council (NSDCC), formerly the National AIDS Control Council (NACC), illustrates the complexities of a government organization undergoing a strategic shift. The NSDCC expanded its focus from HIV control to addressing multiple syndemic diseases and related health factors. This study investigates employee engagement during rebranding the National AIDS Control Council (NACC) to the National Syndemic Diseases Control Council (NSDCC). This transition …

Embracing Digital Disruption In Tanzania: Insights From Mwananchi Communications Ltd's Print-To-Digital Multimedia Journey, Absalom Norman Kibanda

Executive Masters in Media Leadership and Innovation

This capstone study investigates the profound impact of digital transformation on print media, employing Mwananchi Communications Ltd (MCL) in Tanzania as a case study, elucidating the intricate fusion of cultural transformation and strategic shifts in response to this disruption. With an in-depth exploration of theoretical frameworks like Networked Communication Theory and Media Convergence Theory, this study underscores the evolution of MCL's culture and the paradigm shift in the mindset of its staff and readers since the company's strategic embrace of multimedia strategies. MCL's transformative journey, characterized by the adoption of innovative multimedia platforms, including a website, paywall approaches, subscription models, …

Investigating The Role Of Data Analytics In News Production And Distribution: A Case Of Nation Media Group, Uganda, Clare Muhindo

Executive Masters in Media Leadership and Innovation

This study investigates the role of data analytics in news production and distribution in Uganda, using a case study of Nation Media Group, Uganda (NMG-U). The study is framed within the context of the gatekeeping theory, particularly the participatory gatekeeping model, which focuses on the creation of processes, or newsroom routines and norms, that are developed as a direct result of audience input interpreted through audience data. The research had three objectives: (1) to examine how data analytics are integrated into editorial workflows at NMG Uganda. (2) to explore how data analytics shape editorial priorities and (3) to identify strategies …

What Do They Love? A Study Of Digital Media Consumption By Young University Audiences In Uganda, Allan Chekwech

Executive Masters in Media Leadership and Innovation

The proliferation of computers, smartphones, the Internet, social media, and streaming platforms has led to a surge in digital media consumption. Young audiences, especially those aged between 18 and 34, are increasingly turning to digital platforms for entertainment, information, and social interaction, much to the disadvantage of traditional media platforms such as the newspaper, radio and television. As a result, many media players are concerned about what young people consume, especially if they follow any news. Consequently, the desire to understand their news consumption habits on these digital platforms is paramount. Using a quantitative approach, this study got responses from …

Army Rotc Annual Program Report, 2024-2025, University Of Arkansas, Fayetteville. Army Rotc

Army ROTC Annual Program Report

No abstract provided.

[In] Transformation President's Impact Report, Bryant University

Bryant University Communications and Press

The 2025 President's Impact Report highlights Bryant University’s continued excellence in higher education, from its top-tier rankings and dynamic campus life to its hands-on learning experiences and strategic partnerships. Strong financial foundations and visionary leadership solidify its position as an innovative and forward-thinking institution. IN the Lead Bryant's international rankings and thought leadership in prestigious publications reinforce its position as a leader in higher education.

Annual Report, 2024-2025, University Of Arkansas, Fayetteville. College Of Education And Health Professions

College of Education and Health Professions Annual Reports

No abstract provided.

Globalization In Context, Ayu Okvitawanli, Wolfgang Friedlmeier, Rachana Bhangaokar

IACCP Proceedings of the Biennial International Conferences

The Proceedings are divided into two parts: Volume I includes the links to the recorded keynotes and the book of abstracts of the XXVII Congress of the International Association for Cross-Cultural Psychology, 2024. Volume II consists of the individual empirical papers.

From Bitcoin To Courtrooms: The Evolution Of Blockchain Technology And Its Applications, Isabelle Cruz

Wyoming Law Review

Blockchain’s tamper-proof, distributed, and decentralized design has gained popularity during a period of rising cybercrime and data vulnerability. People revere blockchain for its potential to revolutionize various industries and criticize it for its association with unethical and illicit activities. Despite challenges and misconceptions surrounding its prior uses, blockchain technology has continued progressing—offering promising solutions for enhancing data security, transparency, and accountability. This Comment examines the evolution of blockchain technology, its applications, and how it can improve efficiency and enhance public trust in the judicial system. After outlining blockchain technology’s modest beginnings, this Comment theorizes several applications for blockchain in the …

The Role Of Leadership In Creating Dei Plans In U.S. Higher Education, Beatriz Desantiago-Fjelstad, Leslie Darmofal, Kelly Meier, Henry Morris, Luis Posas

Educational Leadership Department Publications

This brief discusses the challenges and strategies in creating Diversity, Equity, and Inclusion (DEI) plans in U.S. higher education. It highlights the importance of leadership in this process, particularly the need for courageous leadership to overcome the barriers posed by resistance to DEI plans. This brief illustrates the complexities of creating DEI plans and offers strategies to foster inclusive environments. The discussion emphasizes the need for a long-term commitment and actionable DEI plans beyond performative steps, instilling confidence in the potential for significant institutional evolution.

Force Of Nature (2024) By Ann E. Burg, Maughn Rollins Gregory

Middle Grades Books

Rachel Carson launched the modern environmental movement with books that combined detailed observations of the natural world, scientific research, and philosophical reflection on humanity’s relationship with nature — all conveyed in poetic language. Ann E. Burg’s fictional biography-in-verse Force of Nature shows how these habits of observation, questioning, reflection, and expression began in Carson’s childhood, and invites readers to follow her lines of inquiry. Can we provide for human well-being without sacrificing the well-being of non-human life? Can we provide for the well-being of certain human populations without sacrificing the well-being of others? Can we indulge our wonder about, and …