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The Effect Of Teaching Using The (Pror) Strategy On Academic Achievement In Science And Student Perseverance Among Fifth-Grade Students., Salam Dawood Ali Al-Jubouri Jun 2025

The Effect Of Teaching Using The (Pror) Strategy On Academic Achievement In Science And Student Perseverance Among Fifth-Grade Students., Salam Dawood Ali Al-Jubouri

Uruk Journal of Human Sciences

The aim of the research is to identify the effect of teaching using the (PROR) strategy on academic achievement in science and student perseverance among fifth-grade students. There is no statistically significant difference at the (0.05) level between the mean scores of the experimental group (who studied using the PROR strategy) and the control group (who studied using the traditional method) in the achievement test.There is no statistically significant difference at the (0.05) level between the mean scores of the experimental group and the control group in the perseverance scale. The researcher adopted a quasi-experimental design, with a sample of …


Resúmenes, Iajbs Ateneo De Manila University Jun 2025

Resúmenes, Iajbs Ateneo De Manila University

Journal of Management for Global Sustainability

No abstract provided.


Dynamic Model Of Stunting Incidents And Policies In Padang City, Elsa Yuniarti, Yulhendri Yulhendri, Fitra Arya Dwi Nugraha, Nurhasan Syah, Iswandi Umar, Heldi Heldi, Nabila Azzahra Jun 2025

Dynamic Model Of Stunting Incidents And Policies In Padang City, Elsa Yuniarti, Yulhendri Yulhendri, Fitra Arya Dwi Nugraha, Nurhasan Syah, Iswandi Umar, Heldi Heldi, Nabila Azzahra

Media Kesehatan Masyarakat Indonesia

Stunting remains a significant public health challenge with complex, interconnected causative factors. Traditional static approaches fail to capture the dynamic relationships between environmental, health, and socioeconomic determinants. Dynamic modeling is essential for understanding these multifaceted interactions and developing effective prevention policies. Despite declining trends, Padang City's high prevalance of stunting necessitates urgent, targeted interventions to achieve national targets. This study aims to develop a dynamic model analyzing stunting factors in Padang City and formulate effective prevention policies. A quantitative descriptive method with a dynamic systems approach was employed. Primary data were obtained through stakeholder questionnaires, while secondary data were obtained …


Psychosocial Factors And Prevalence Of Stress In Early Pregnancy: A Study In Makassar City, Jumriani Ansar, Asri C Adisasmita, Sudarto Ronoatmodjo, Farid Husin, Muliani Ratnaningsih Jun 2025

Psychosocial Factors And Prevalence Of Stress In Early Pregnancy: A Study In Makassar City, Jumriani Ansar, Asri C Adisasmita, Sudarto Ronoatmodjo, Farid Husin, Muliani Ratnaningsih

Media Kesehatan Masyarakat Indonesia

Stress during pregnancy can negatively impact the health of both the mother and the fetus, especially in the first trimester, which is a period of intense physical and emotional adaptation. This study aims to determine the prevalence and psychosocial factors associated with the occurrence of stress in first-trimester pregnant women in Makassar City. This study uses a cross-sectional design involving 256 first-trimester pregnant women from five public health centers in the suburban areas of Makassar City. Data were collected through interviews using a structured questionnaire. The Edinburgh Postnatal Depression Scale (EPDS10) instrument was used to measure stress levels. Analysis was …


Mapping Trends And Patterns In Tuberculosis And Tobacco Use: Insights From A Bibliometric Analysis Of 25 Years Of Research, Meyi Yanti, Erwani Erwani, Radian Ilmaskal, Masrizal Masrizal, Sohel Rana Jun 2025

Mapping Trends And Patterns In Tuberculosis And Tobacco Use: Insights From A Bibliometric Analysis Of 25 Years Of Research, Meyi Yanti, Erwani Erwani, Radian Ilmaskal, Masrizal Masrizal, Sohel Rana

Media Kesehatan Masyarakat Indonesia

Tuberculosis (TB) and tobacco use represent two of the most pervasive global health challenges, with a particularly profound impact in Low and Middle-Income Countries (LMICs). Although numerous reviews have explored the clinical and epidemiological associations between TB and smoking. A systematic analysis of publication trends is lacking. This study aims to address this gap by providing a comprehensive bibliometric analysis of the intersection between TB and tobacco use, mapping its evolution, key research themes, collaboration networks, and underexplored areas. This study utilized a bibliometric method. Data from 13,876 articles indexed in Scopus were analyzed using RStudio, VOSViewer, and OpenRefine. PLOS …


Lifestyle Activities That Contribute To The Risk Of Stroke In Indonesia: Smoking, Consuming Fatty Foods And Soft Drinks, Janu Purwono, Irwan Budiono, Oktia Woro Kasmini Handayani Jun 2025

Lifestyle Activities That Contribute To The Risk Of Stroke In Indonesia: Smoking, Consuming Fatty Foods And Soft Drinks, Janu Purwono, Irwan Budiono, Oktia Woro Kasmini Handayani

Media Kesehatan Masyarakat Indonesia

Stroke is the leading cause of death and disability in Indonesia, with a high prevalence reported in the Indonesian Health Survey (IHS) 2023. Smoking, consumption of fatty foods, and intake of soft drinks are major risk factors contributing to the increasing incidence of both ischemic and hemorrhagic stroke. This study aims to analyze the effects of smoking habits, fatty food consump-tion, and soft drink intake on stroke incidence in Indonesia using secondary data from IHS 2023. A quantitative design was applied, with chi-square test analysis performed using SPSS. The study population comprised all individuals recorded in the IHS 2023, which …


Determinants Of Food Management Behavior On Food Waste Reduction And Household Food Security Through Expenditure Efficiency And Energy Consumption, Prita Dhyani Swamilaksita, Yayuk Farida Baliwati, Drajat Martianto, Dodik Briawan Jun 2025

Determinants Of Food Management Behavior On Food Waste Reduction And Household Food Security Through Expenditure Efficiency And Energy Consumption, Prita Dhyani Swamilaksita, Yayuk Farida Baliwati, Drajat Martianto, Dodik Briawan

Media Kesehatan Masyarakat Indonesia

Food Waste (FW) in urban households remains a serious issue as it contributes to economic losses, reduced dietary quality, and weakened food security. This study aims to identify the dominant factors influencing food management behavior, FW generation, and their implications for household food security in urban settings. A cross-sectional design was applied with urban households as the study population, and samples were selected using purposive sampling. Data were analyzed using Structural Equation Modeling (SEM) within the framework of the Theory of Planned Behavior (TPB) and Nudge Theory. The results indicate that attitude (β = 0.42; p < 0.01), subjective norm (β = 0.31; p < 0.05), and perceived behavioral control (β = 0.36; p < 0.01) significantly influence intention toward food management. Furthermore, intention strongly predicts actual food management behavior (β = 0.55; p < 0.001), which subsequently reduces FW (β = –0.47; p < 0.001). Reduced FW positively affects both food expenditure efficiency (β = 0.39; p < 0.01) and energy intake adequacy (β = 0.34; p < 0.05), two critical indicators of urban household food security. Behavioral factors play a crucial role in reducing FW and strengthening food security in urban households. Therefore, behavior-based interventions using TPB and Nudge Theory are recommended to be integrated into food education programs, household assistance, and urban food security policies to ensure effectiveness and sustainability.


Risk Analysis Of Pesticide Exposure Associated With Reduced Cholinesterase Levels In Indonesian Farm Workers: A Meta-Analysis, R Azizah, Juliana Jalaludin, Muhammad Addin Rizaldi, Globila Nurika, Mochammad Sholehhudin, Zaneta Aaqilah Salsabila, Zafira Nuha Naura Jun 2025

Risk Analysis Of Pesticide Exposure Associated With Reduced Cholinesterase Levels In Indonesian Farm Workers: A Meta-Analysis, R Azizah, Juliana Jalaludin, Muhammad Addin Rizaldi, Globila Nurika, Mochammad Sholehhudin, Zaneta Aaqilah Salsabila, Zafira Nuha Naura

Media Kesehatan Masyarakat Indonesia

Pesticide exposure remains a major occupational health problem, with the World Health Organization (WHO) reporting between 1 and 5 million cases of pesticide poisoning annually among agricultural workers. This study aimed to analyze the risk factors associated with pesticide poisoning by conducting a meta-analysis of published research. The meta-analysis was performed in four stages: data abstraction, statistical analysis using JASP Version 0.18.3, heterogeneity testing, and publication bias assessment. The random-effects model was applied to the variables of Personal Protective Equipment (PPE) use and length of work, as the heterogeneity test indicated significant variation between studies (p = 0.001). In contrast, …


Validating The Malay Version Of Adolescent Sexual And Reproductive Health Knowledge And Attitudes Questionnaires, Gerraint Gillan Ahi, Md Mizanur Rahman, Rafazila Ramli, Rasitasam Safii, Jacey Lynn Minoi, Stephanie Chua Hui Li, Ahmad Sofian Bin Shminan, Lee Jun Choi Jun 2025

Validating The Malay Version Of Adolescent Sexual And Reproductive Health Knowledge And Attitudes Questionnaires, Gerraint Gillan Ahi, Md Mizanur Rahman, Rafazila Ramli, Rasitasam Safii, Jacey Lynn Minoi, Stephanie Chua Hui Li, Ahmad Sofian Bin Shminan, Lee Jun Choi

Media Kesehatan Masyarakat Indonesia

Adolescent Sexual and Reproductive Health (SRH) knowledge is crucial for informed decision-making, yet cultural barriers in Malaysia limit open discussions, creating significant knowledge gaps. This study validated the Malay version of the Adolescent SRH Knowledge and Attitudes Questionnaire to address this need. The validation process included expert content review (6 panelists), face validity testing (30 respondents), and psychometric analysis among 100 adolescents in Sarawak. The questionnaire demonstrated excellent content validity as rated by the experts and strong face validity among adolescents. The knowledge domain showed high internal consistency (α = 0.935), while the attitude domain had moderate reliability (α = …


Urban School Nutrition: Student And Teacher Perspectives On Creating A Healthier Food Environment, Rahayu Indriasari, Yessy Kurniati, Safrullah Amir, Indra Fajarwati Ibnu, Balqis Balqis Jun 2025

Urban School Nutrition: Student And Teacher Perspectives On Creating A Healthier Food Environment, Rahayu Indriasari, Yessy Kurniati, Safrullah Amir, Indra Fajarwati Ibnu, Balqis Balqis

Media Kesehatan Masyarakat Indonesia

Changes in lifestyle and eating habits can affect food choices for adolescents, impacting their nutritional intake. Schools are pivotal in shaping healthy eating behaviors. This qualitative study explores the perspectives of secondary school students and teachers on strategies to improve the healthy food environment in an urban school. Two focus group discussions with students and one with teachers, along with one in-depth interview with the school principal, were conducted at a junior high school in Makassar city. The audio recordings were transcribed and analyzed thematically to identify key themes. Students appeared to be aware of the importance of healthy eating …


Dampak Covid-19 Terhadap Kecepatan Penyesuaian Struktur Modal: Studi Perbandingan Antara Perusahaan Sharia-Compliant Dan Non-Compliant Di Indonesia, Abdul Karim, Karina Wulandari Jun 2025

Dampak Covid-19 Terhadap Kecepatan Penyesuaian Struktur Modal: Studi Perbandingan Antara Perusahaan Sharia-Compliant Dan Non-Compliant Di Indonesia, Abdul Karim, Karina Wulandari

Jurnal Manajemen dan Usahawan Indonesia

This study aims to examine the impact of the COVID-19 pandemic on capital structure adjustment among firms in Indonesia, with a focus on differences between Sharia-compliant and non-compliant companies. The research utilizes panel data from non-financial firms listed on the Indonesia Stock Exchange (IDX) during the 2017–2022 period. Capital structure adjustment is analyzed using panel regression methods, controlling for variables such as profitability, growth, firm size, tangibility, liquidity, and income volatility. The findings indicate that the pandemic increased leverage and accelerated capital structure adjustment overall. However, Sharia-compliant firms exhibited a slower adjustment speed compared to non-compliant firms, due to constraints …


Peran Gdp Dalam Memoderasi Pengaruh Environmental, Social, Governance (Esg) Terhadap Kinerja Perusahaan Dalam Sektor Jasa Di Negara Asean-5 Periode 2019–2023, Syadinda Azra Rafinka, Mona Ridho Sidjabat Jun 2025

Peran Gdp Dalam Memoderasi Pengaruh Environmental, Social, Governance (Esg) Terhadap Kinerja Perusahaan Dalam Sektor Jasa Di Negara Asean-5 Periode 2019–2023, Syadinda Azra Rafinka, Mona Ridho Sidjabat

Jurnal Manajemen dan Usahawan Indonesia

This study analyze the role of GDP in moderating the influence of environmental, social, governance (ESG) on the performance of service sector companies. The data is collected from Refinitiv Eikon Database including 81 sample companies in the services sector in ASEAN-5 countries for the period 2019–2023 that have complete ESG combined score and individual pillar scores (environmental, social and governance) of each company. This study uses balanced panel data with fixed effect robust model estimation. The results show that environmental score and ESG combined score have a significant negative effect on firm performance. However, there is no significant effect of …


Fun At Work Dari Sudut Pandang Aparatur Sipil Negara (Asn): Studi Kualitatif Pada Instansi Pemerintahan Di Indonesia, Febrian Wibawa, Nayunda Andhika Sari Jun 2025

Fun At Work Dari Sudut Pandang Aparatur Sipil Negara (Asn): Studi Kualitatif Pada Instansi Pemerintahan Di Indonesia, Febrian Wibawa, Nayunda Andhika Sari

Jurnal Manajemen dan Usahawan Indonesia

The concept of fun at work is often discussed in various studies as an activity that supports a positive work climate and provides a variety of positive experiences for employees. However, there is debate in seeing the impact of implementing fun at work in the workplace, especially in the context of public services. To date, research related to fun at work in the context of public services or government institutions is still very limited. By focusing on the civil servants or ASNs in Indonesia, this study aims to explore the perceptions and experiences of fun at work for ASNs.

This …


“Gen Z Malas Dan Gampang Resign?”: Analisis Wacana Kritis Atas Representasi Negatif Dalam Media Massa, Muhammad Gaza Jun 2025

“Gen Z Malas Dan Gampang Resign?”: Analisis Wacana Kritis Atas Representasi Negatif Dalam Media Massa, Muhammad Gaza

Jurnal Manajemen dan Usahawan Indonesia

This study employs Norman Fairclough’s Critical Discourse Analysis to examine how Indonesian online media construct negative stereotypes of Generation Z in the workplace. Based on an analysis of 15 national news articles (January–May 2025), the findings reveal that narratives such as “lazy,” “spoiled,” and “quick to resign” are consistently reproduced through word choice, institutional quotes, and framing aligned with traditional work values. The discourse operates on three levels: micro (biased linguistic structures), meso (digital market logic), and macro (intergenerational value tensions). These representations are not mere reflections of reality but symbolic practices that reinforce dominant work structures. A critical reading …


Perizinan Usaha Wisata Kawasan Karst Gunung Sewu: Diskresi Penataan Ruang Dan Ancaman Lingkungan Hidup, Siti Rahma Novikasari, Aditya Khrisna Murti Jun 2025

Perizinan Usaha Wisata Kawasan Karst Gunung Sewu: Diskresi Penataan Ruang Dan Ancaman Lingkungan Hidup, Siti Rahma Novikasari, Aditya Khrisna Murti

Jurnal Hukum & Pembangunan

The Gunung Sewu Karst Area is located in Gunungkidul, Wonogiri, and Pacitan Regencies. It has a unique geological formation so it was designated as a Global Geopark by the United Nations Education Scientific and Cultural Organization (UNESCO) in 2015. However, the Gunungkidul Regional Government is targeting the regional economy condition by proposing to reduce the number of karst landscape area and granting tourism business permits. These actions had serious impacts on geological, hydrological and ecological conditions. Therefore, this study aims to examine: 1) How is the conformity between tourism business permits and spatial planning provisions for the karst area? 2) …


อำนาจของผู้จัดการมรดกในกฎเกณฑ์ว่าด้วยการขัดกันแห่งกฎหมาย (The Power Of An Estate Administrator In Conflict Of Laws Rules), Arnon Sriboonroj Jun 2025

อำนาจของผู้จัดการมรดกในกฎเกณฑ์ว่าด้วยการขัดกันแห่งกฎหมาย (The Power Of An Estate Administrator In Conflict Of Laws Rules), Arnon Sriboonroj

Chulalongkorn University Law Journal

อำนาจของผู้จัดการมรดกตามกฎเกณฑ์ว่าด้วยการขัดกันแห่งกฎหมายเป็นเรื่องที่มีความสำคัญ โดยเฉพาะอย่างยิ่งในสภาพการณ์ปัจจุบันที่โลกได้ก้าวเข้าสู่ยุคแห่งความไร้พรมแดนจึงอาจทำให้ทรัพย์สินของเจ้ามรดกกระจัดกระจายอยู่ได้ในหลายประเทศ การที่จะพิจารณาว่ากฎหมายของประเทศใดเป็นกฎหมายที่ใช้บังคับกับนิติสัมพันธ์ในเรื่องอำนาจของผู้จัดการมรดกนั้นย่อมเป็นหน้าที่ของกฎเกณฑ์ว่าด้วยการขัดกันแห่งกฎหมาย สำหรับระบบกฎหมายขัดกันว่าด้วยอำนาจของผู้จัดการมรดกนั้นอาจแบ่งได้เป็น 2 ระบบ กล่าวคือ ระบบที่แยกเรื่องผู้จัดการมรดกออกจากเรื่องทรัพย์มรดก และระบบที่ไม่แยกเรื่องผู้จัดการมรดกออกจากเรื่องทรัพย์มรดก ในขณะที่เมื่อพิจารณาถึงกฎเกณฑ์ว่าด้วยการขัดกันแห่งกฎหมายนั้น กฎหมายขัดกันของแต่ละประเทศได้ให้การยอมรับจุดเกาะเกี่ยวในการค้นหากฎหมายที่ใช้บังคับกับเรื่องอำนาจของผู้จัดการมรดกไว้แตกต่างกัน โดยกฎหมายขัดกันของอังกฤษได้อาศัยกฎหมายภายในกำหนดถึงอำนาจของผู้จัดการมรดก ในขณะที่กฎหมายขัดกันของประเทศจีนได้อาศัยกฎหมายแห่งถิ่นที่ทรัพย์นั้นตั้งอยู่เป็นจุดเกาะเกี่ยวส่วนภายใต้ระบบกฎหมายขัดกันของไทยนั้นไม่ได้มีการกำหนดกฎเกณฑ์ในการเลือกกฎหมายเพื่อใช้บังคับกับเรื่องอำนาจของผู้จัดการมรดกไว้เป็นการเฉพาะ จึงต้องใช้กลไกการอุดช่องว่างของกฎหมายตามมาตรา 3 พระราชบัญญัติว่าด้วยการขัดกันแห่งกฎหมาย พุทธศักราช 2481 ซึ่งกำหนดให้ใช้กฎเกณฑ์ทั่วไปแห่งกฎหมายระหว่างประเทศแผนกคดีบุคคลบังคับ


Analysis Of Students' Creative Thinking Skills In Learning Hydrocarbons By Using Daily Life-Based Practicum Method, Yenni Kurniawati, Laras Dyaz Handayani, Dea Ramadani, Nurhikmah Sari Jun 2025

Analysis Of Students' Creative Thinking Skills In Learning Hydrocarbons By Using Daily Life-Based Practicum Method, Yenni Kurniawati, Laras Dyaz Handayani, Dea Ramadani, Nurhikmah Sari

Jurnal Pendidikan Sains

Creative thinking skill is a competence of the 21st century that is needed very much and needs to be increased by utilizing chemistry in life. This research aimed at analyzing student creative thinking skills in experimental and control groups and finding out the effect of the daily life-based practical work learning method on student creative thinking skills. This research was conducted in the eleventh grade at High School 1 Pekanbaru on the hydrocarbon lesson. The quasi-experimental method was used in this research with pretest-posttest and non-equivalent control group designs. The instruments used in this research were essay tests, observation, and …


Exploring Students’ Perceptions Of Science Laboratory Practices: A Comparative Study Between Rural And Urban Schools, Safrida Dwiningsih, Ina Lestari, Roma Ismi, Sri Wahyu Rahmadina, Masdalena Sinaga, M. Rahmad Jun 2025

Exploring Students’ Perceptions Of Science Laboratory Practices: A Comparative Study Between Rural And Urban Schools, Safrida Dwiningsih, Ina Lestari, Roma Ismi, Sri Wahyu Rahmadina, Masdalena Sinaga, M. Rahmad

Jurnal Pendidikan Sains

This study aims to analyze students' perceptions of the implementation of science laboratory practicums at public middle school 020 Pekanbaru and public middle school 7 Pangkalan Kuras, Riau Province. Using a quantitative survey method, this study involved 75 student respondents. The instrument used was a questionnaire consisting of 26 statements, analyzed descriptively. The results show that students' perceptions of the preparation, implementation, and conclusion stages of the practicum fall into the "good" category, with urban schools having a higher percentage. In conclusion, the implementation of practicums in urban schools is better than in rural schools, bringing attention to the need …


Digital Comic Learning Media (E-Comic) To Increase Student Learning Interest In Reaction Rate Material At High School, Berliana Afsohin Nabila, Achmad Lutfi Jun 2025

Digital Comic Learning Media (E-Comic) To Increase Student Learning Interest In Reaction Rate Material At High School, Berliana Afsohin Nabila, Achmad Lutfi

Jurnal Pendidikan Sains

This study aims to develop digital comic learning media that is effective in increasing students' interest in learning about reaction rate material, focusing on the media's validity, practicality, and overall effectiveness. This research utilizes the research and development method with the ADDIE model. Research instruments were used, including validity sheets to assess the media's validity, student activity observations, and student response questionnaires to evaluate the media's practicality, as well as student interest questionnaires and learning outcomes to measure the effectiveness of the learning media. The findings show that validity results showed a mode score of 4, indicating a very valid …


Analysis Of Misconceptions In Learning Biology Mutation Material At High School, Fitri Hayati Kurnia, Tri Wahyu Agustina, Wahyuni Handayani Jun 2025

Analysis Of Misconceptions In Learning Biology Mutation Material At High School, Fitri Hayati Kurnia, Tri Wahyu Agustina, Wahyuni Handayani

Jurnal Pendidikan Sains

This research aims to analyze student misconceptions regarding mutation material in class XII. The research method uses a descriptive approach with mixed methods, which combines qualitative and quantitative methods. Qualitative data was obtained through interviews with biology teachers, while quantitative data was obtained through questionnaires and essay tests on students. The research results indicate that the material that students like is growth and development, while the material they don't like is gene mutation and genetic material. Students' misconceptions occur due to preconception aspects, associative thinking, and a lack of understanding of genetic concepts. It was found that students' understanding of …


The Predictive Ability Of Amh For Positive Pregnancy In Women Undergoing Icsi, Balsam Kahtan Mohammed, Sahar Muhssin Muhammad Jun 2025

The Predictive Ability Of Amh For Positive Pregnancy In Women Undergoing Icsi, Balsam Kahtan Mohammed, Sahar Muhssin Muhammad

Al-Qadisiyah Medical Journal

Background: Anti-Müllerian hormone (AMH) is a member of the transforming growth factor-beta family and is chemical structure is a dimeric glycoprotein. The granulosa cells of the antral follicles are the source of secretion of this hormone. It has been shown that serum level of such hormone can be a marker of the count of ovarian follicles and hence can be used as a marker of ovarian reserve. Aim of study: By examining the clinical pregnancy rate (CPR) in relation to AMH levels in women who had ICSI cycles, this retrospective study sought to ascertain the predictive usefulness of AMH levels …


Evaluating The Efficacy Of Venetoclax-Based Regimens In Relapsed/Refractory Acute Leukemia: A Real-World Study From Three Chinese Oncology Centers, Wei Zhang, Liyang Huang, Ming Zhao, Rui Chen, Huiwen Liu Jun 2025

Evaluating The Efficacy Of Venetoclax-Based Regimens In Relapsed/Refractory Acute Leukemia: A Real-World Study From Three Chinese Oncology Centers, Wei Zhang, Liyang Huang, Ming Zhao, Rui Chen, Huiwen Liu

Muthanna Medical Journal

Background: Relapsed or refractory (R/R) acute leukemia poses a significant therapeutic challenge, with limited options and poor prognosis. Venetoclax, a BCL-2 inhibitor, has shown promise in frontline acute myeloid leukemia (AML), but its real-world utility in R/R settings remains underexplored. Objective: To evaluate the efficacy and safety of venetoclax-based regimens in adult patients with R/R acute leukemia treated in routine clinical practice across three tertiary oncology centers in China. Methods: A retrospective multicenter study was conducted on 70 patients with R/R acute leukemia (AML or ALL) treated between January 2020 and December 2023. Patients received venetoclax combined …


Targeting The Pi3k/Akt/Mtor Pathway In Hormone-Receptor Positive Breast Cancer: A New Frontier In Precision Therapy, Rina Mehra, Arjun Nair, Sneha Iyer, Karthik Raman, Meera Joshi Jun 2025

Targeting The Pi3k/Akt/Mtor Pathway In Hormone-Receptor Positive Breast Cancer: A New Frontier In Precision Therapy, Rina Mehra, Arjun Nair, Sneha Iyer, Karthik Raman, Meera Joshi

Muthanna Medical Journal

Background: Hormone receptor-positive (HR+) breast cancer represents the most common subtype among Indian women and is typically managed with endocrine therapies. However, resistance to such therapies-often driven by activation of the PI3K/AKT/mTOR signaling pathway-poses a significant clinical challenge and necessitates the development of targeted treatment strategies. Objective: This review aims to evaluate the molecular basis, therapeutic efficacy, safety profiles, and real-world applicability of PI3K/AKT/mTOR inhibitors in the management of HR+ breast cancer, with a focus on their relevance within the Indian healthcare landscape. Methods: A comprehensive narrative review was conducted by searching PubMed, Scopus, Web of Science, and Google Scholar …


Integrating Molecular Insights Into Treatment Strategies: The Pi3k/Akt/Mtor Axis In Hr+ Breast Cancer Management In India, Ananya Deshmukh, Raghavendra B. Iyer, Priyanka Nair, Vivek Sharma Jun 2025

Integrating Molecular Insights Into Treatment Strategies: The Pi3k/Akt/Mtor Axis In Hr+ Breast Cancer Management In India, Ananya Deshmukh, Raghavendra B. Iyer, Priyanka Nair, Vivek Sharma

Muthanna Medical Journal

Background: The PI3K/AKT/mTOR pathway plays a pivotal role in endocrine resistance among hormone receptor-positive (HR+) breast cancer patients. Despite growing global access to pathway-targeted therapies, the clinical integration of molecular diagnostics in India remains limited. This study investigates the prevalence and prognostic implications of PI3K/AKT/mTOR pathway activation in HR+ breast cancer using patient-derived tumor tissue. Methods: This prospective observational study analyzed tumor samples from 60 HR+ breast cancer patients treated at a tertiary oncology center in India. PIK3CA mutation status was assessed via PCR-based genomic testing. Protein expression of p-AKT and mTOR was evaluated using immunohistochemistry. Survival data …


Obesity And Smoking Status: Relationships With Specific Pulmonary Functions In University Of Babylon College Of Pharmacy Students, Safa W. Aziz Jun 2025

Obesity And Smoking Status: Relationships With Specific Pulmonary Functions In University Of Babylon College Of Pharmacy Students, Safa W. Aziz

Muthanna Medical Journal

Adult pulmonary function impairment is associated with both smoking and obesity, albeit the consequences vary from person to person. This study aims to evaluate the relationship between smoking and obesity and their relationship to specific pulmonary functions in a selected group of the population (University of Babylon College of Pharmacy students, Iraq). Materials and Methods: The observational study was carried out on 90 male students at the college pharmacy in the University of Babylon, Iraq. Students enrolled in this study were aged between 19-23 years. The control group (30 males) from general students in the college pharmacy without smoking, …


Cross-Section Study Of Iron Deficiency Anemia In A Group Of Adolescents: Frequency And Contributing Factors, Murtaza Hassan Hadi, Mostafa Abdalla Abdelkareem, Nasser Ghaly Yousif Jun 2025

Cross-Section Study Of Iron Deficiency Anemia In A Group Of Adolescents: Frequency And Contributing Factors, Murtaza Hassan Hadi, Mostafa Abdalla Abdelkareem, Nasser Ghaly Yousif

Muthanna Medical Journal

Background: Iron deficiency anemia (IDA) remains a significant global health concern, particularly among adolescents. This study investigated the prevalence and contributing factors of IDA among adolescents at Al Hussain Teaching Hospital, addressing a critical knowledge gap in the Iraqi healthcare context. Methods: A cross-sectional study was conducted on 77 adolescent patients (ages 12-18 years) from October 01, 2024, to January 30, 2025. Data collection included hemoglobin levels, serum ferritin measurements, dietary iron intake assessment, and socioeconomic status evaluation. Statistical analysis employed descriptive statistics, chi-square tests for categorical variables, and multivariate analysis to identify contributing factors. Results: The …


Mono And Polymicrobial Biofilm Formation By Candida Species And Staphylococcus Aureus, Ghadeer Ali Saad, Mohammad Hashim Al-Yasiri Jun 2025

Mono And Polymicrobial Biofilm Formation By Candida Species And Staphylococcus Aureus, Ghadeer Ali Saad, Mohammad Hashim Al-Yasiri

Muthanna Medical Journal

Polymicrobial biofilms, composed of fungi and bacteria such as Candida and Staphylococcus aureus, exhibit interactions dependent on environmental factors and organism type. The objective of this investigation was to evaluate the ability of S. aureus and Candida species to construct mono and polymicrobial biofilms. Candida species and S. aureus were isolated from various clinical sources. The identification of these isolates was based on morphological and biochemical characteristics as well as using Vitek 2 compact. Biofilm formation was evaluated using flat-bottom microtiter plate assay with crystal violet. A total of 41 S. aureus, 15 C. tropicalis, 14 C. …


Therapeutic Potential Of Bone Marrow-Derived Stem Cells In The Treatment Of Ewing Sarcoma: New Approach, Nasser Ghaly Yousif, Fadhil G. Alamran, Ahmed Altimimi Jun 2025

Therapeutic Potential Of Bone Marrow-Derived Stem Cells In The Treatment Of Ewing Sarcoma: New Approach, Nasser Ghaly Yousif, Fadhil G. Alamran, Ahmed Altimimi

Muthanna Medical Journal

Background: Ewing Sarcoma is a challenging pediatric bone cancer with limited treatment options, particularly in advanced stages. Recent research has highlighted the potential of bone marrow-derived stem cells (BMSCs) as a novel therapeutic approach due to their tumor-targeting capabilities and ability to modulate the tumor microenvironment. Objective: This study aims to explore the therapeutic potential of BMSCs in the treatment of Ewing Sarcoma, focusing on innovative strategies that leverage their unique properties to enhance treatment efficacy and patient outcomes. Methods: This study involved a comprehensive review of the literature on BMSCs and their application in cancer therapy, …


Estimation Of Serum Electrolytes And Renal Function In Patients With Kidney Failure In Mosul City, Sumayah Kasim, Abdullah Khaleil Ibrahim, Asmaa Abdulwahab Abdughafoor Jun 2025

Estimation Of Serum Electrolytes And Renal Function In Patients With Kidney Failure In Mosul City, Sumayah Kasim, Abdullah Khaleil Ibrahim, Asmaa Abdulwahab Abdughafoor

Al-Qadisiyah Medical Journal

Background: Renal failure, additionally referred to as kidney failure, is an illness in which the kidneys are unable to filter bodily waste from the circulation. This can cause an accumulation of harmful substances and the electrolytes in the human body, which can result in a variety of unpleasant side effects. Electrolytes are minerals that are essential for proper body function, including maintaining fluid balance, regulating nerve and muscle function, and supporting heart health. Imbalances in electrolyte levels can occur in individuals with kidney failure due to the kidneys' inability to regulate electrolyte levels properly. Objectives:  The purpose of this study …


The Prevalence Of Endothelial Nitric Oxide Gene Polymorphisms In Iraqi Patients With Essential Hypertension, Ghufran K Salman, Bassim I Mohammad Jun 2025

The Prevalence Of Endothelial Nitric Oxide Gene Polymorphisms In Iraqi Patients With Essential Hypertension, Ghufran K Salman, Bassim I Mohammad

Al-Qadisiyah Medical Journal

Background: Due to the polygenic character of hypertension, it is particularly challenging to identify the single nucleotide polymorphisms most likely to be linked with essential hypertension and also the connections between certain genes and treatment responses in various ethnic groups. One of important genes is eNOS gene which encode eNOS enzyme that mediate NO production.  Our study involve rs1799983 (G894T) and rs2070744 (T-786C) of eNOS gene. The objective of this observational cross-sectional descriptive study is to examine frequencies of allele of eNOS3 genes. Methods: ninety hypertensive patients were recruited by specialist cardiologist and conducted at AL-Diwaniyah teaching hospital and department …