Digital Commons Network^™

Aiding Depth Perception In Initial Drone Training: Evidence From Camera-Assisted Distance Estimation, John Murray, Steven Richardson, Keith Joiner, Graham Wild

Research outputs 2022 to 2026

Remotely Piloted Aircraft (RPA) pilots frequently experience difficulties with depth perception, particularly when estimating distances between the drone and environmental obstacles. This study evaluates whether the use of onboard camera imagery can improve exocentric distance estimation accuracy among ab initio drone pilots operating under visual line-of-sight (VLOS) conditions. Two groups of undergraduate students performed distance estimation tasks at 20 and 50 m. One group used direct observation only to estimate the exocentric distance between the drone and an obstacle. The second group, as well as direct observation, had access to a live video feed from the drone’s onboard camera via …

Blue Light Is A Key Factor In Regulating Stomatal Movement, Transpiration Rate And Aba Metabolism Under Varying Vapour Pressure, Sheona Noemi Innes, Sara Brunborg Jakobsen, Rikke Bryn Røsåsen, Haider Ali, Knut Asbjørn Solhaug, Jorunn Elisabeth Olsen, Sissel Torre

Research outputs 2022 to 2026

Vapour pressure deficit (VPD) and blue light (BL) are import signals for stomatal regulation and highly relevant during cultivation of economically important crops such as cucumber in controlled environments. However, the information about combined effects of VPD and BL and the regulation of abscisic acid (ABA) in this respect, is limited and seems to vary between species. This study investigated how moderate (1.12 kPa) or low (0.28 kPa) VPD combined with 5% or 30% BL affect the foliar ABA metabolism, transpiration rate, nutrient uptake, and growth in well-watered cucumber plants (Cucumis sativus ‘Quatro’). Additional BL, regardless of VPD, resulted in …

Evaluating The Influence Of Carbon Quantum Dots On Starch-Based Bioplastics: Toward Potential Food Packaging Applications, Shima Jafarzadeh, Mitra Golgoli, Zeinab Qazanfarzadeh, Mehrdad Forough, Peng Wu, Wendy Timms, Colin J. Barrow, Minoo Naebe, Masoumeh Zargar

Research outputs 2022 to 2026

Developing biodegradable food packaging films is crucial for reducing dependence on petroleum-based plastics. In this study, nitrogen-doped carbon quantum dots (CDs) were synthesized from citric acid and ethylenediamine via hydrothermal treatment and incorporated into sago starch films at concentrations of 0.5 %, 1 %, 3 %, and 4 % w/w of total solids using a solution casting method. The effects of CDs on structural, thermal, antioxidant, optical, and physicochemical properties were systematically investigated. CD addition enhanced the UV-shielding ability of the films. At 4 % CD content, UV transmittance decreased by 56.4 % (UVA), 66.7 % (UVB), and 73.9 % …

Foundations And Strategic Vision Of The Canadian Translational Geroscience Network, Guy Hajj-Boutros, Andréa Faust, John Muscedere, Perry Kim, Gilles Gouspillou, Lea Harrington, James L. Kirkland, George A. Kuchel, Jeremy Van Raamsdonk, R. Jane Rylett, Chantal Autexier, Louis R. Lapierre, Michael Kobor, Mohammad Auais, Ann Beliën, Jeroen Aerssens, George Sutphin, Kenneth Rockwood, Alexandra Papaioannou, Marc Sim, Jamie Justice, Nancy Mayo, Gustavo Duque

Research outputs 2022 to 2026

Geroscience is an emerging interdisciplinary field that explores the biological connections between aging and the development of chronic diseases, with the ultimate goal of identifying interventions to extend healthspan and delay age-related conditions. Recognizing the growing importance of this field, the Canadian Translational Geroscience Network (geroscience.ca) was officially launched during a conference held in Montreal on September 5-6, 2024. Building on the momentum of successful Geroscience meetings in Toronto and Montreal in 2023, this milestone event marked a transformative step forward for geroscience in Canada. This event brought together key stakeholders, including the Canadian Frailty Network (CFN), the Canadian Institutes …

Incorporating Waste Plastics Into Pavement Materials: A Review Of Opportunities, Risks, Environmental Implications, And Monitoring Strategies, Ali Ghodrati, Nuha S. Mashaan, Themelina Paraskeva

Research outputs 2022 to 2026

The integration of waste plastics into pavement materials offers a dual benefit of enhancing road performance and mitigating the environmental burden of plastic waste. This review critically examines the opportunities and challenges associated with incorporating waste plastics in pavement construction, with an emphasis on their impact on the mechanical properties, durability, and life cycle performance of pavements. Special attention is given to the environmental implications, particularly the potential generation and release of micro- and nano-plastics during the pavement life cycle. This paper further evaluates current monitoring and analytical methodologies for detecting plastic emissions from road surfaces and explores emerging approaches …

Models Of Care For Indigenous Children In Rural And Remote Settings: A Global Scoping Review, Joseph Freeman, Thomas Stubbs, Verity Chadwick, Anita Pickard, Tuguy Esgin, Elizabeth J. Elliott, Alexandra Martiniuk

Research outputs 2022 to 2026

Indigenous communities internationally have demonstrated remarkable strength despite significant challenges. Health disparities among Indigenous peoples persist due to historical injustices and ongoing racial discrimination, not inherent vulnerabilities. Disparities are rooted in a legacy of colonisation, systemic exclusion, and socio-economic inequities impacting access to healthcare, education, and employment. Preliminary searches show limited literature on models of care for remote living Indigenous children. This review aimed to identify internationally, effective models of care for Indigenous children in rural and remote areas. A scoping review was conducted, analysing literature on models of care for remote Indigenous children. This study followed the JBI’s Scoping …

Real-World Continuous Smartwatch-Based User Authentication, N. Al-Naffakh, N. Clarke, F. Li, P. Haskell-Dowland

Research outputs 2022 to 2026

User authentication is often regarded as the "gatekeeper"of cyber security. It has, however, long suffered from significant usability issues that have resulted in research focussing upon frictionless and transparent biometric approaches. Activity-based user authentication - a technique that authenticates a user by what they are physically doing at a specific point in time has attracted significant attention, particularly due to the increasing popularity of smartwatches. This research aims to overcome limitations in prior work by exploring the viability of the approach in real-world conditions. The study presents two principal experiments, one focused upon a constrained environment to provide a control …

Rural Cancer Survivors' Perceived Delays In Seeking Medical Attention, Diagnosis And Treatment: Findings From A Large Qualitative Study, Alyssa Taglieri-Sclocchi, Ingrid Bindicsova, Susannah K. Ayre, Michael Ireland, Sonja March, Fiona Crawford-Williams, Suzanne Chambers, Jeff Dunn, Belinda C. Goodwin, Elizabeth A. Johnston

Research outputs 2022 to 2026

Aims: To investigate rural cancer survivors' self-reported reasons for perceived delays in initial cancer detection and treatment. Methods: Within a cohort study, adult cancer survivors who had travelled > 50 km for cancer care, staying at subsidised accommodation lodges in city centres in Queensland, Australia, were invited to complete a structured interview on perceived delays in: (i) seeking medical attention, (ii) receiving their diagnosis and (iii) commencing treatment. Content analysis was used to map self-reported reasons for perceived delays at each step, which were then categorised based on the perceived source: (i) personal, (ii) healthcare professional, (iii) healthcare system or (iv) …

Social Service Inclusion Of Immigrants Through The Lens Of Human Rights In Australia, Obed Adonteng-Kissi, Matthew Mabefam, Nnaemeka Meribe, Frank Darkwa Baffour, Elizabeth Archibong

Research outputs 2022 to 2026

Motivation: A human-centred approach to social service design is necessary to encourage social service inclusion and to offer an avenue for social service action in Australia and globally. Purpose: The purpose of this article is to ascertain the extent to which social service providers design their services to include immigrants. Approach and methods: We draw on literature exploring social service inclusion and the perspectives of 27 social workers and immigrant service users. Semi-structured interviews were conducted with eight social workers and 19 immigrants who were purposefully selected from Brisbane, Townsville, Melbourne and Sydney. We applied the capability theoretical approach of …

The Association Between Sexually Transmitted Infections And Pregnancy Outcomes In The Northern Territory, Australia: A Population-Based Cohort Study, Jennifer Dunne, Gizachew A. Tessema, Matthew Legge, Sylvester Dodzi Nyadanu, Aditi Roy, Amanuel T. Gebremedhin, Jacqueline Hendriks, Tricia Reid-Moore, Gavin Pereira

Research outputs 2022 to 2026

Background: Often asymptomatic in nature, sexually transmitted infections (STIs) are highly prevalent in women of reproductive ages, leading to adverse perinatal outcomes. This study investigated the association between STIs during pregnancy and the risk of adverse perinatal outcomes using comprehensive population-linked data from the Northern Territory (NT), Australia. Methods: This population-based retrospective cohort study examined births (live births and stillbirths) from the NT Perinatal Data Collection and the NT Notifiable Diseases register from 2005 to 2020. All singleton births (N = 59,465) were included, along with infectious disease notifications of four STIs that occurred during pregnancy: chlamydia, gonorrhoea, trichomoniasis, and …

The Response And Recovery Of Carbon And Water Fluxes In Australian Ecosystems Exposed To Severe Drought, C. Stephens, B. Medlyn, L. Williams, J. Knauer, A. Inbar, E. Pendall, S. K. Arndt, J. Beringer, C. M. Ewenz, N. Hinko-Najera, L. B. Hutley, P. Isaac, M. Liddell, W. Meyer, C. E. Moore, J. Cranko Page, R. Silberstein, W. Woodgate

Research outputs 2022 to 2026

Climate change-driven increases in drought risk pose a critical threat to global carbon and water cycles. However, ecosystem-scale responses remain poorly quantified, particularly for severe, multiyear drought events. We addressed this gap by examining ecosystem-scale carbon and water flux sensitivity to the extreme 2018–19 drought in Australia using data from 14 eddy covariance flux sites. The ecosystems span grasslands and semi-arid woodlands to tropical and temperate forests. The driest sites (classed as “grass” and “very dry”) experienced drastic productivity impacts, with a 65% decrease in Gross Primary Productivity (GPP) over 2 years relative to the pre-drought average. However, fluxes in …

The Therapeutic Potential Of Butyrate And Lauric Acid In Modulating Glial And Neuronal Activity In Alzheimer’S Disease, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Lotta E. Oikari, Prashant Bharadwaj, Vijay Jayasena, Ralph N. Martins, Wanakulasuriya Mary Ann Dipika Binosha Fernando

Research outputs 2022 to 2026

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by amyloid-β plaque accumulation, tau tangles, and extensive neuroinflammation. Neuroinflammation, driven by glial cells like microglia and astrocytes, plays a critical role in AD progression. Initially, these cells provide protective functions, such as debris clearance and neurotrophic support. However, as AD progresses, chronic activation of these cells exacerbates inflammation, contributing to synaptic dysfunction, neuronal loss, and cognitive decline. Microglia release pro-inflammatory cytokines and reactive oxygen species (ROS), while astrocytes undergo reactive astrogliosis, further impairing neuronal health. This maladaptive response from glial cells significantly accelerates disease pathology. Current AD treatments primarily aim …

Time Alters Distinct Memories Driven By Sensory Prediction Errors And Task Errors In Sensorimotor Adaptation, Li Ann Leow, Welber Marinovic, Scott Albert, Timothy J. Carroll

Research outputs 2022 to 2026

Prior learning can impair future learning when the requirements of the two memories conflict, a phenomenon termed anterograde interference. In sensorimotor adaptation, the passage of time between initial and future learning can reduce such interference effects, leading to the interpretation that time consolidates motor memories, protecting motor memories from interference. However, we still do not fully understand how time affects learning, as some studies found no effects of time on interference. One possible explanation for such inconclusive findings is that time has distinct effects on the multiple processes underpinning sensorimotor adaptation, and these processes may compensate for each other's effects …

Winds Of Change: Charting A Pathway To Ecosystem Monitoring Using Airborne Environmental Dna, Rachel L. Tulloch, Clare I.M. Adams, Matthew A. Barnes, Elizabeth L. Clare, Henrik C. Van De Ven, Andrew Cridge, Francisco Encinas-Viso, Kristen Fernandes, Dianne M. Gleeson, Erin Hill, Anna J.M. Hopkins, Anna M. Kearns, Gracie C. Kroos, Anna J. Macdonald, Francesco Martoni, Angela Mcgaughran, Todd G.B. Mclay, Linda E. Neaves, Paul Nevill, Andrew Pugh, Kye J. Robinson, Fabian Roger, Tracey V. Steinrucken, Mieke Van Der Heyde, Cecilia Villacorta-Rath, Jenny Vivian

Research outputs 2022 to 2026

Airborne environmental DNA (airborne eDNA) analysis leverages the globally ubiquitous medium of air to deliver broad species distribution data and support ecosystem monitoring across diverse environments. As this emerging technology matures, addressing critical challenges and seizing key opportunities will be essential to fully realize its potentially transformative impact. In June 2024, the Southern eDNA Society convened over 100 researchers, industry leaders, and biodiversity management stakeholders in a landmark workshop to evaluate the current state of airborne eDNA research and chart a course for future development. Participants explored opportunities for integrating airborne eDNA into existing monitoring systems, but they unanimously agreed …

Amyloid Accumulation, Brain Atrophy, And Cognitive Decline In Emergent Alzheimer's Disease, Ying Xia, Pierrick Bourgeat, Vincent Doré, Jurgen Fripp, Yen Ying Lim, Simon M. Laws, Christopher Fowler, Christopher C. Rowe, Colin L. Masters, Elizabeth J. Coulson, Paul Maruff

Research outputs 2022 to 2026

Introduction : Emergent Alzheimer's disease (AD) represents a transitional stage where cognitively unimpaired (CU) individuals exhibit subthreshold but increasing amyloid-β (Aβ) levels. The impact of Aβ accumulation on brain volume loss and cognition during this early stage remains unclear. Methods: This retrospective cohort study analyzed data from 408 CU participants who were initially Aβ− (< 15 Centiloids) and followed for up to 15 years. Changes in basal forebrain and hippocampal volume, along with domain-specific cognitive performance, were compared between those who progressed to Aβ+ (≥20 Centiloids) and those who remained Aβ−. Results: Sixty-five CU participants progressed to Aβ+, indicating emergent AD, and showed faster Aβ accumulation and subtle memory decline. However, no significant differences in rate of BF and hippocampal atrophy were observed between groups. Discussion: The results suggest that during this emergent phase of AD, Aβ accumulation is associated with episodic memory loss, in the absence of detectable accelerated brain atrophy. Highlights: Identified cognitively unimpaired individuals in the emergent stage of Alzheimer's disease (AD). Emergent AD exhibits a greater rate of amyloid-β (Aβ) accumulation. No accelerated volume loss detected in the basal forebrain or hippocampus. Emergent AD is also associated with a subtle decline in memory. Early Aβ accumulation may impair cognitive function before structural atrophy.

Descending Asymmetry In Proximate, Mobile And Digital Care: Chinese Older People Grandparenting Across Distance Within China And Overseas, Catriona Stevens, Rachel Murphy, Yu Huang, Loretta Baldassar

Research outputs 2022 to 2026

This article juxtaposes cases of grandparents who provide care for their grandchildren in two broad types of migrant families: (1) families where some members have migrated from the Chinese countryside to larger cities and (2) families where some members have migrated from China to Australia. By examining the proximate, mobile and digital forms of their grandparenting care labour, this article demonstrates the surprising durability and stability of care repertoires across distance and class. Despite the great differences of their migration geographies and family resources, these families nonetheless all demonstrate remarkably similar repertoires of caregiving articulated with reference to similar cultural …

Human Rights Perspectives In Social Work Practice With African Immigrants In Australia: 'It Starts With Respecting Them And Making Them Feel Like Humans', Obed Adonteng-Kissi, Frank Darkwa Baffour, Matthew Mabefam, Nnaemeka Meribe, Elizabeth Archibong

Research outputs 2022 to 2026

Increasing restrictionism and xenophobic policies in Western host countries curtail and endanger immigrants' civil and political rights as well as socio-economic well-being. This study is guided by the critical race theory (CRT), which provides a very important structure to critique social work practice with immigrants from a human rights lens and unpack the intersections of race, racism, and power. The objective of this study is to explore immigrants' perspectives on social work practices that prioritize human rights in Australia. To achieve this, a total of twenty-seven participants were interviewed, including eight social workers and nineteen immigrants of African background service …

Pre-Registration Student Nurses' Evaluation After Enrolling On To A 4-Week Art Workshop ​, Hazel Cowls, Chloe Weekes-Dyer

School of Nursing and Midwifery

No abstract provided.

Work-Integrated Learning In Business And Management: Gauging Impact And Opportunities For Growth, Denise Jackson

Research outputs 2022 to 2026

Work-Integrated Learning's (WIL) widely heralded role in developing future-capable graduates has boosted growth in diverse WIL offerings in Australia. Yet comparatively low participation among certain student groups and ongoing talent shortages highlight the need for further expansion, particularly in disciplines where WIL is optional. This study explores student engagement in different types of WIL and the impact it has on student employability and graduate labour force outcomes. Survey data were gathered from over 60,000 graduates of bachelor and postgraduate Business and Management degrees across Australia and compared to other disciplines where WIL is traditionally elective. Despite recent rises in student …

Does External Labour Market Activeness Affect Agency Problem?, Yuyun Claudie Huang, Jamie Yixing Tong, Joey W. Yang

Research outputs 2022 to 2026

This study examines the relationship between external labour market and the agency problem. Exploiting the staggered recognition of the Inevitable Disclosure Doctrine (IDD) by US state courts to capture a drop in external labour market activeness, we examine whether and how the activeness of external labour market affects managers' empire building behaviour. We find that in IDD-recognising states, managers are less engaged in empire-building activity, thus reducing agency costs and improving firm performance. The effect is concentrated in managers with heightened career concern where their firms experience higher degrees of financial constraints or operate within an industry of more intense …

Eco-Friendly Additives For Biodegradable Polyesters: Recent Progress In Performance Optimization And Environmental Impact Reduction, Ahmad Fayyazbakhsh, Nima Hajinajaf, Hamed Bakhtiari, Michael Feuchter, Ilaria Improta, Ehsan Salehi, Sara Kamal Shahsavar, Marketa Julinova, Amirehsan Ghasemi, Bita Ghasemi, Reza Afsharnia, Marek Koutný, Young Cheol Chang

Research outputs 2022 to 2026

Biodegradable polymers have emerged as principal alternatives to petroleum-based polymers, which exert a detrimental impact on the environment. Among these, biodegradable polyesters stand out as particularly noteworthy, renowned for their exceptional properties that find application across diverse industries, including food packaging, biomedical devices, and agriculture. This comprehensive analysis delves into the impact of various additives, with a focus on eco-friendly ones, on biodegradable polyesters, as evidenced by recent research endeavors. The additives are systematically categorized to provide a nuanced understanding within distinct industrial contexts. In the exploration of these additives, a meticulous classification is employed, ensuring a focused analysis of …

Postoperative Care Pathways For Patients Following Coronary Artery Bypass Grafting Surgery: An Observational Study, Dima Nasrawi, Sharon Latimer, Debbie Massey, Brigid M. Gillespie

Research outputs 2022 to 2026

Aims: The aim of this study was to describe the postoperative care pathway, with phase 1 cardiac rehabilitation (CR) delivery, for adult patients following coronary artery bypass grafting (CABG) surgery at one large hospital in Queensland, Australia. Design and methods: This observational study involved structured observations, patient electronic medical record audits, and field notes to gather postoperative data. Four continuous hours of patient and healthcare professional (HCP) observations gathered at 30-min intervals occurred on 12 separate days over a 1-month period (February–March 2023). We observed post-CABG patients and HCPs involved in delivering direct care. Data were gathered on the clinical …

Recruitment And Retention Of Intensive Care Unit Survivors In Follow-Up Studies: A Systematic Review, Beverley Ewens, Vivien Kemp, Yvonne Middlewick, Amanda Towell-Barnard, Lisa Whitehead

Research outputs 2022 to 2026

Background: Engaging intensive care unit survivors in research is challenging. Studies have reported recruitment and attrition rates; details are lacking on retention strategies and attrition. Objective: The aim of this study was to explore barriers and enablers to recruitment and retention in research of people post intensive care discharge. Methods: A convergent mixed-method review using the Joanna Briggs Institute (JBI) methodology considered studies that reported on recruitment, retention, and attrition rates of adult post–intensive care survivors in longitudinal studies. CINAHL Ultimate (CINAHL+), PubMed, Excerpta Medica Database (EMBASE), PsycINFO, Scopus, Proquest Health, and Medical Collection were searched in March 2024 using …

A Power Dependence Model Of The Impact Of Leader Impostorism On Supervisor Support And Undermining: The Moderating Role Of Power Distance, Zihan Liu, Zihan Liu, Feng Qiu, Keith Leavitt, Xingyu Wang, Ziyang Tang

Research Collection Lee Kong Chian School Of Business

Leaders, often perceived as possessing exceptional confidence and competence, are not immune to feelings of self-doubt. Leader impostorism describes the experience that one’s attributes, experiences, skills, and abilities fall short of the standards expected in the leadership role, resulting in a sense of deception in fulfilling leadership responsibilities. While existing research has examined the antecedents and individual outcomes of leader impostorism, its implications for leaders’ treatment of subordinates remain largely unexplored. In this research, we investigate the downstream consequences of leader impostorism on behaviors directed toward subordinates. Integrating research on leader impostorism with power dependence theory, we propose that for …

Real-World Continuous Smartwatch-Based User Authentication, N. Al-Naffakh, N. Clarke, F. Li, P. Haskell-Dowland

School of Engineering, Computing and Mathematics

User authentication is often regarded as the “gatekeeper” of cyber security. It has, however, long suffered from significant usability issues that have resulted in research focussing upon frictionless and transparent biometric approaches. Activity-based user authentication—a technique that authenticates a user by what they are physically doing at a specific point in time has attracted significant attention, particularly due to the increasing popularity of smartwatches. This research aims to overcome limitations in prior work by exploring the viability of the approach in real-world conditions. The study presents two principal experiments, one focused upon a constrained environment to provide a control and …

Hadronic Vacuum Polarization For The Muon G-2 From Lattice Qcd: Long-Distance And Full Light-Quark Connected Contribution, Alexei Bazavov, Claude Bernard, David Anthony Clarke, Christine Davies, Carleton Detar, Aida X. El-Khadra, María Elvira Gámiz Sánchez, Steven Gottlieb, Anthony V. Grebe, Leon Hostetler, William Jay, Hwancheol Jeong, Andreas Kronfeld, Shaun Lahert, Jack Laiho, Gerard Lepage, Michael Lynch, Andrew Lytle, Craig Mcneile, Ethan Neil, Curtis Peterson, James Simone, Jacob W Sitison, Ruth S. Van De Water, Alejandro Vaquero Avilés-Casco, Craig Mcneile

School of Engineering, Computing and Mathematics

We present results for the dominant light-quark connected contribution to the long-distance window of the hadronic vacuum polarization (HVP) contribution to the muon g-2 from lattice quantum chromodynamics. Specifically, with a new determination of the lattice scale on MILC's physical-mass HISQ ensembles, using the Ω^{-} baryon mass, we obtain a result of a_{μ}^{ll,LD}(conn)=400.2(2.3)_{stat}(3.7)_{syst}[4.3]_{total}×10^{-10}. Summing this result with our recent determinations of the light-quark connected contributions to the short- and intermediate-distance windows, we obtain a subpercent precision determination of the light-quark-connected contribution to HVP of a_{μ}^{ll}(conn)=655.2(2.3)_{stat}(3.9)_{syst}[4.5]_{total}×10^{-10}. Finally, as a consistency check, we verify that an independent analysis of the full contribution …

Monitoring Morphological Variability Of Gravel Barriers Using 2d Lidar, Robert Jones, Nieves Valiente, Chris Blenkinsopp, Mark Davidson

School of Biological and Marine Sciences

No abstract provided.

Long-Term Cytoreduction Outcomes With Or Without Heated Intraperitoneal Chemotherapy For Colorectal Peritoneal Metastases, Michael G White, Paula Marincola Smith, Neal Bhutiani, Beth Helmink, Norman Galbraith, Scott Kopetz, Michael Overman, Paul Mansfield, Keith Fournier, Abhineet Uppal

Faculty, Staff and Student Publications

Background: Patients with peritoneal metastases from colorectal adenocarcinoma (CRC) benefit from cytoreductive surgery (CRS). However, the role of heated intraperitoneal chemotherapy (HIPEC) remains unclear. We studied associations between HIPEC, peritoneal disease-free survival (PDFS), and overall survival (OS) in patients with CRC undergoing CRS.

Study design: All patients with CRC undergoing CRS between 2008 and 2023 were retrospectively identified at our center. Patient clinicodemographic factors were determined by chart review. OS and PDFS were evaluated using the Kaplan-Meier method. Associations between clinical factors and survival were determined using Cox proportional hazard models.

Results: A total of 147 patients were identified with …

Outcomes And Toxicity Following 3 Or More Definitive Courses Of Thoracic Radiation Therapy For Non-Small Cell Lung Cancer, Abigael Odwuor, Percy Lee, Joe Y Chang, Saumil Gandhi, Zhongxing Liao, Steven H Lin, Aileen Chen, Quynh-Nhu Nguyen, Michael S O'Reilly, Stephen G Chun, Julianna Bronk, David Qian, Matthew S Ning

Faculty, Staff and Student Publications

Purpose: Salvage re-irradiation is increasingly utilized to manage non-small cell lung cancer (NSCLC) locoregional recurrence or new lung primaries in previously treated areas. There is sparse information on efficacy and toxicity profile. We report a large experience of patients treated with multiple courses of definitive radiation for new and recurrent NSCLC.

Methods and materials: Medical records of patients who underwent ≥ 3 definitive thoracic radiation therapy (RT) courses for new or recurrent NSCLC at our cancer center from 2012 through 2021 were retrospectively reviewed following institutional review board approval. Toxicity was graded per Common Terminology Criteria for Adverse Events (CTCAE) …

Incomplete Toxicity Reporting And Use Of Toxicity-Minimizing Language In Phase Iii Oncology Trials, Avital M Miller, Adina H Passy, Alexander D Sherry, Ramez Kouzy, Joseph Abi Jaoude, Timothy A Lin, Gabrielle S Kupferman, Esther J Beck, Pavlos Msaouel, Ethan B Ludmir

Faculty, Staff and Student Publications

Purpose: This study aimed to determine complete toxicity reporting (CTR), and the use of subjective toxicity-minimizing language (TML) among phase III oncology trials.

Methods: Two-arm superiority-design phase III oncology trials published from 2002 to 2020 were reviewed for toxicity data. CTR was defined as reporting total adverse events (TAEs), total serious adverse events (SAEs), total deaths, and study therapy discontinuations because of toxicity. Guideline concordance was defined according to guidelines published in the BMJ (defined as reporting total SAEs, total deaths, and study therapy discontinuations because of toxicity). TML was defined as a set of terms that subjectively downplay the …