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Articles 74071 - 74100 of 1737590
Full-Text Articles in Entire DC Network
The King’S Two Bodies: A Study In Mediaeval Political Theology, Ernst H. Kantorowicz
The King’S Two Bodies: A Study In Mediaeval Political Theology, Ernst H. Kantorowicz
Hannah Arendt Marginalia - All
Princeton, N.J., Princeton University Press, 1957
Call #: JC385 .K25
Contains marginalia, underlining, marginal lining, and endnotes
PDF Information: 92 pages – 8 MB
Allocation Of Interest And R&D Under Regs. Sec. 1.861-8(E): Questions From The Entrails, Michael Adler
Allocation Of Interest And R&D Under Regs. Sec. 1.861-8(E): Questions From The Entrails, Michael Adler
Tax Adviser
No abstract provided.
Health-Related Quality Of Life Of Patients With And Without Diabetes On Hemodialysis In China: A Comparative Correlational Study, Ziting Han, Aurawamon Sriyuktasuth, Warunee Phligbua
Health-Related Quality Of Life Of Patients With And Without Diabetes On Hemodialysis In China: A Comparative Correlational Study, Ziting Han, Aurawamon Sriyuktasuth, Warunee Phligbua
Journal of Health Research
Background: Limited evidence exists on differences in health-related quality of life (HRQOL) and its determinants between diabetic and non-diabetic hemodialysis patients in China. This comparative correlational study aimed to compare HRQOL and identify associated determinants among patients with and without diabetes in Xinxiang, China.
Methods: A total of 300 hemodialysis patients (150 diabetic, 150 non-diabetic) were recruited through convenience sampling. Data were collected using a personal information form, the Kidney Disease Quality of Life Short-Form (KDQOL-SF), the Treatment Adherence Scale for Maintenance Hemodialysis, and the Family Support Scale. Independent t-tests compared HRQOL scores between groups, and multiple linear regression identified …
Developing A Participatory Resilience Quotient Program For Village Health Volunteers In Rural Thailand: An Action Research Study In The Post-Covid-19 Era, Orathai Katkhaw, Somkid Juwa, Taweewun Srisookkum, Tienthong Takaew, Sunanta Tangnitipong, Surangkana Chairinkam
Developing A Participatory Resilience Quotient Program For Village Health Volunteers In Rural Thailand: An Action Research Study In The Post-Covid-19 Era, Orathai Katkhaw, Somkid Juwa, Taweewun Srisookkum, Tienthong Takaew, Sunanta Tangnitipong, Surangkana Chairinkam
Journal of Health Research
Background: Village Health Volunteers (VHVs) play a vital role in community health; however, their psychological resilience remains underexplored. This study aimed to assess the resilience levels of VHVs in rural Thailand and evaluate the effectiveness of a resilience enhancement program.
Methods: This action research study was conducted between April and October 2022 with 476 VHVs, selected through stratified random sampling across two sub-districts and five villages per sub-district in Phayao Province. Data collection included interviews and self-report questionnaires. A four-week Resilience Quotient (RQ) program was implemented with 40 VHVs, focusing on five structured activities: self-reflection, stress management, problem-solving, …
Variability Of Immune Response To Coronavac In The Indonesian Population: A Retrospective Cohort Study In Bantaeng, South Sulawesi,Indonesia, Sitti Musafirah Arif, Juliani Ibrahim, Antariksa P. Winarno, Andi Nur Anna, Andi Weri Sompa, Ami Febriza S. Achmad, Nurdiana Nurdiana, Zulkifli Zulkifli, Irwan Ashari
Variability Of Immune Response To Coronavac In The Indonesian Population: A Retrospective Cohort Study In Bantaeng, South Sulawesi,Indonesia, Sitti Musafirah Arif, Juliani Ibrahim, Antariksa P. Winarno, Andi Nur Anna, Andi Weri Sompa, Ami Febriza S. Achmad, Nurdiana Nurdiana, Zulkifli Zulkifli, Irwan Ashari
Journal of Health Research
Background: The COVID-19 vaccine, including CoronaVac, is crucial in reducing severe infections and mortality due to COVID-19. However, variability in antibody responses across different populations remains a subject of investigation. This study aimed to evaluate the impact of age and BMI on Immunoglobulin G (IgG) antibody levels three months post-CoronaVac vaccination in a healthy Indonesian cohort.
Methods: A retrospective cohort study was conducted on 299 healthy individuals aged 18–70 in Bantaeng, South Sulawesi, Indonesia. IgG levels against the SARS-CoV-2 spike protein receptor-binding domain (RBD) were measured using enzyme-linked immunosorbent assay (ELISA). Blood samples were collected about 90 ± 7 days …
Pulse Diagnosis In Thai Traditional Medicine: Comparing Tri-Dhātu Characteristics In Each Innate Body Element Between Experts And Device, Athippat Tantiwongsekunakorn, Suksalin Booranasubkajorn, Thanaphak Chaopeerapong, Angkana Apichartvorakit, Pravit Akarasereenont
Pulse Diagnosis In Thai Traditional Medicine: Comparing Tri-Dhātu Characteristics In Each Innate Body Element Between Experts And Device, Athippat Tantiwongsekunakorn, Suksalin Booranasubkajorn, Thanaphak Chaopeerapong, Angkana Apichartvorakit, Pravit Akarasereenont
Journal of Health Research
Background: Pulse diagnosis in Thai Traditional Medicine (TTM) evaluates the balance of the Tri-Dhātu—Vata, Pitta, and Semha—and their interaction with innate body elements (Dhātu Chao Ruean; DCR). Despite its clinical significance, scientific evidence and quantitative tools remain limited. This study aimed to compare Tri-Dhātu pulse characteristics across different DCR types using expert assessment and the DMP-Life™ pulse diagnostic device.
Method: One-way ANOVA with post hoc analysis was applied to data from 159 participants, each evaluated at six pulse positions for shape, depth, power, and rhythm by Applied Thai Traditional Medicine (ATM) experts and the DMP-Life™ device.
Results: There were no …
Managing Covid-19-Related Stigma In Border Trade Communities: A Qualitative Study In Mae Hong Son, Thailand, Siwaporn Mahathamnuchock
Managing Covid-19-Related Stigma In Border Trade Communities: A Qualitative Study In Mae Hong Son, Thailand, Siwaporn Mahathamnuchock
Journal of Health Research
Background: In the border trade communities of Mae Hong Son Province, Thailand, misinformation and fear surrounding COVID-19 led to increased discrimination.
Method: This study aims to: (1) examine the different forms of stigma, (2) understand how affected individuals manage and cope with stigma, and (3) investigate community-based interventions to reduce stigma in border regions. An interpretative paradigm was used in a qualitative research design. A total of 18 participants—including local traders, housewives facing mobility challenges, a community leader, and healthcare workers were interviewed semi-structurally from August to December 2022. Key data patterns were identified by thematic analysis.
Results: There …
Classification Of Dental Adverse Events Using Iterative Qualitative Analysis, Kiti Siriwatana, Sathirakorn Pongpanich
Classification Of Dental Adverse Events Using Iterative Qualitative Analysis, Kiti Siriwatana, Sathirakorn Pongpanich
Journal of Health Research
Background: Effective incident reporting systems (IRS) are essential in dentistry for identifying and preventing adverse events (AEs), with standardized classifications ensuring consistent incident categorization. This study aimed to develop and validate a classification system for dental patient safety incidents based on a 5-year case study at the Dental Hospital at Chulalongkorn University, Thailand.
Methods: An iterative qualitative approach was used. A literature review explored existing accreditation standards and AE classification systems. Incident reports from 2018–2022 informed a draft classification system aligned with Thailand’s National Reporting and Learning System and accreditation standards. Reports from 2023 were used for validation. An expert …
Identifying Gaps In The Multidrug-Resistant Tuberculosis (Mdr-Tb) Cascade Of Care: Barriers And Improvement Opportunities In North Maluku, Indonesia, Eko Sudarmo Dahad Prihanto, Prayudi Santoso, Elsa Pudji Setiawati, Rovina Ruslami
Identifying Gaps In The Multidrug-Resistant Tuberculosis (Mdr-Tb) Cascade Of Care: Barriers And Improvement Opportunities In North Maluku, Indonesia, Eko Sudarmo Dahad Prihanto, Prayudi Santoso, Elsa Pudji Setiawati, Rovina Ruslami
Journal of Health Research
Background: The Multidrug-Resistant-Tuberculosis (MDR-TB) Cascade of Care includes MDR-TB treatments from suspicion to completion. Implementation gaps can lower treatment success. This study aimed to identify gap causes and opportunities to improve MDR-TB treatment in North Maluku, Indonesia
Methods: To identify gaps, we conducted in-depth interviews and focus group discussions with health workers at Puskesmas (Indonesian government's primary healthcare centers) and hospitals, MDR-TB patients, and patients’ families. Thematic analysis was conducted using the Consolidated Framework for Implementation Research (CFIR) for health workersand the health belief model (HBM) approach for patients and their families.
Results: Significant gaps were found …
Effects Of The Case Management With Community Support Program On Health Behaviors And Outcomes In Thai Buddhist Monks With Type 2 Diabetes And Early-Stage Chronic Kidney Disease, Napawadee Tangtrongvisolkit, Noppawan Piaseu, Porntip Malathum, Basia Belza
Effects Of The Case Management With Community Support Program On Health Behaviors And Outcomes In Thai Buddhist Monks With Type 2 Diabetes And Early-Stage Chronic Kidney Disease, Napawadee Tangtrongvisolkit, Noppawan Piaseu, Porntip Malathum, Basia Belza
Journal of Health Research
Background: Patient engagement and community support are vital for promoting self-care in monks with early-stage chronic kidney disease (CKD). This study investigated the impact of an 18-week Case Management with Community Support Program (CMCSP) on self-care activities and health outcomes (hemoglobin A1c, HbA1c), blood pressure, and estimated glomerular filtration rate (eGFR) in Thai Buddhist monks with type 2 diabetes mellitus (T2DM) and CKD.
Methods: A Randomized Controlled Trial (RCT) with pretest and post-test measures was employed. Eighty-two monks with T2DM and stage 1–2 CKD were recruited from 33 subdistricts in Thailand and randomly assigned into experimental (n = …
Mystical Epistemologies: Understanding Divine Love Through Ibn 'Arabi And Thomas Aquinas, Janai Wright
Mystical Epistemologies: Understanding Divine Love Through Ibn 'Arabi And Thomas Aquinas, Janai Wright
Undergraduate Honors Theses
This paper explores the epistemological role of love in the mystical frameworks of Muhyiddin Ibn ‘Arabi and Thomas Aquinas, two significant figures of medieval philosophy and theology. Though rooted in distinct monotheistic traditions—Islamic mysticism and Christian scholasticism—both thinkers share a foundation in Aristotelian thought, from which they derive skepticism regarding the intellect's capacity to fully comprehend or relate to the divine. Instead, they elevate love as the essential means to attaining knowledge of God. By comparing Ibn ‘Arabi’s concept of the heart with Aquinas’ notion of the will, the paper elucidates how each philosopher positions love as transcending the limitations …
Supporting Participation In Daily Occupations, Quality Of Life, And Well-Being For Individuals With Dementia In Nursing Homes, Julianne M. Sta.Ana
Supporting Participation In Daily Occupations, Quality Of Life, And Well-Being For Individuals With Dementia In Nursing Homes, Julianne M. Sta.Ana
Department of Occupational Therapy Entry-Level Capstone Projects
This capstone project aimed to enhance the quality of life, well-being, and occupational participation of individuals with dementia residing in nursing homes through the implementation of an eight-week occupational therapy-based program. By addressing unmet needs through personalized, meaningful activities such as cognitive stimulation, physical activities, and social engagement, this project seeks to reduce cognitive decline and improve emotional well-being. The SLUMS and GDS were used to evaluate the program’s effectiveness. Ultimately, this project sought to understand occupational therapy’s role in supporting dementia care in nursing homes.
Utilizing Wearable Technology To Improve Pots Diagnostic Testing, Monique Watson, Damen Wilson, Matthew Ward
Utilizing Wearable Technology To Improve Pots Diagnostic Testing, Monique Watson, Damen Wilson, Matthew Ward
Discovery Undergraduate Interdisciplinary Research Internship
Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia characterized by a heart rate (HR) increase ≥30 beats/minute (bpm) within 10 minutes of standing from a supine position, without a significant blood pressure drop. POTS can diminish quality of life with symptoms including tachycardia, headaches, and fatigue. Despite established diagnostic criteria, POTS is often underrecognized or misdiagnosed due to its episodic nature. Symptoms may not consistently be present during diagnostic testing, leading to false negatives during in-office testing. Wearables offer a promising solution through continuous physiological monitoring. Individuals with hypermobile Ehler-Danlos Syndrome (hEDS), a population in which POTS is …
Improving Anxiety Screening In Active-Duty Military: Policy Recommendation For Implementing Ham-A Alongside Gad-7, Alex Judkins
Improving Anxiety Screening In Active-Duty Military: Policy Recommendation For Implementing Ham-A Alongside Gad-7, Alex Judkins
Student Scholarly Projects
Practice Problem: Military personnel appear to be at increased risk for mood and stress-related conditions, such as anxiety and depression. These are frequently associated with traumatic brain injury (TBI), yet existing policies and practices may not fully capture this symptom complexity.
PICOT: For healthcare policymakers and providers (P), how does a policy review and recommendation for implementing the HAM-A screening tool for anxiety (I), compared to continued reliance on GAD-7 (C), impact the early identification and policy alignment for somatic and psychic anxiety management among active-duty military personnel (O)?
Evidence: Investigating psychological illnesses and their physiological manifestations in isolation fails …
Artificial Intelligence-Based Digital Pathology Using H&E-Stained Whole Slide Images In Immuno-Oncology: From Immune Biomarker Detection To Immunotherapy Response Prediction., Jessica Zhang, Horyun Choi, Yeseul Kim, Jonghanne Park, Sukjoo Cho, Eugene Kim, Allen Cho, Ju Young Lee, Jaeyoun Choi, Christmann Low, Chan Mi Jung, Emma J Yu, Jeffrey Chuang, Lee Cooper, Young Kwang Chae
Artificial Intelligence-Based Digital Pathology Using H&E-Stained Whole Slide Images In Immuno-Oncology: From Immune Biomarker Detection To Immunotherapy Response Prediction., Jessica Zhang, Horyun Choi, Yeseul Kim, Jonghanne Park, Sukjoo Cho, Eugene Kim, Allen Cho, Ju Young Lee, Jaeyoun Choi, Christmann Low, Chan Mi Jung, Emma J Yu, Jeffrey Chuang, Lee Cooper, Young Kwang Chae
Faculty Research 2025
Immuno-oncology and the advent of immunotherapies, in particular immune checkpoint inhibitors (ICIs), have fundamentally altered the way we treat cancer. Yet only a small subset of patients actually responds to ICIs, and many face significant adverse effects, making the accurate selection of patients for ICIs essential to the work of immuno-oncology. Immune biomarkers, such as programmed death-ligand 1, microsatellite instability/defective mismatch repair, and tumor mutational burden have been developed for patient selection and stratification for ICIs, though their predictive abilities remain limited. This is due to several challenges: lack of adequate tissue sampling, the time-consuming and subjective nature of manual …
The Impact Of Cell Phones And Social Media On Social And Emotional Development Of High School Students, Laura Nash
The Impact Of Cell Phones And Social Media On Social And Emotional Development Of High School Students, Laura Nash
Masters Projects
Studies suggest that social media can have a negative impact on the social and emotional development of adolescents when overused or abused. This paper examines the benefits of social media and several of the adverse effects of problematic social media use. A few of the adverse effects can carry over into the school setting, resulting in students missing valuable instruction time and not being fully engaged in the learning environment. This project proposal is intended to educate parents and school employees about hazards of problematic social media use and the tools that are readily available to monitor the content that …
Comparative Dosimetric Evaluation Of Single-Beam And Two-Beam Grid Therapy In Head And Neck Cancers, Stephanie Scott Stinson
Comparative Dosimetric Evaluation Of Single-Beam And Two-Beam Grid Therapy In Head And Neck Cancers, Stephanie Scott Stinson
Masters Projects
This study aimed to evaluate whether a single-beam or two-beam configuration in GRID therapy offers superior tumor coverage to the Gross target volume(GTV) and organ-at-risk (OAR) sparing in head and neck cancer patients. Ten patients previously treated with GRID therapy to the left neck were retrospectively selected. For each patient, single-beam and two-beam plans were generated using consistent field size and energy. Dosimetric comparisons were performed using dose-volume histograms (DVHs), focusing on the highest dose received at any single point( dmax) and the average radiation dose delivered across an entire volume (dmean), and the volume covered by the 70% and …
Quality Improvement Project Impacting Healthcare Providers’ Knowledge And Self-Efficacy On Peripheral Artery Disease In An Outpatient Cardiovascular Clinic, Nikki Naphaphone Phanyoraj
Quality Improvement Project Impacting Healthcare Providers’ Knowledge And Self-Efficacy On Peripheral Artery Disease In An Outpatient Cardiovascular Clinic, Nikki Naphaphone Phanyoraj
Doctor of Nursing Practice Projects
Peripheral artery disease (PAD) affects over 200 million people worldwide and contributes to functional limitations, decline in quality of life, and increased risk of cardiovascular morbidity and mortality. Failure to effectively screen patients for PAD can lead to delayed treatment and poorer health outcomes. Early detection and intervention are key to altering the disease progression, reducing complications, and improving health outcomes. The purpose of the quality improvement project is to impact the knowledge and self-efficacy of the healthcare providers working in the outpatient cardiovascular clinic on PAD. A quasi-experimental design with pre- and post-test PAD knowledge exam and a pre- …
The Impact Of The Implementation Of A Code Lavender Stress Management Program On Post-Surgical Critical Care Nurses’ Stress, Solange Ngoundjou
The Impact Of The Implementation Of A Code Lavender Stress Management Program On Post-Surgical Critical Care Nurses’ Stress, Solange Ngoundjou
Student Scholarly Projects
Practice Problem: Post-surgical critical care nurses face a variety of stressful events when providing patient care. And there is a strong relationship between job stress, provision of patient care, patient satisfaction, and the overall well-being of the organization.
PICOT Question: For post-surgical critical nurses who are part of a stressful event (P), do evidence-based stress management strategies (I) compared to the current practice (C), reduce stress (O) within 8 weeks (T)?
Evidence: The evidence that guided this project change is based on John Hopkins’ nursing evidence-based practice model, and Lewin’s Change theory.
Intervention: The Code Lavender …
The Multiband Imaging Survey For High-Alpha Planets (Mishaps). I. Preliminary Constraints On The Occurrence Rate Of Hot Jupiters In 47 Tucanae, Alison L. Crisp, Jonas Klüter, Marz L. Newman, Matthew T. Penny, Thomas G. Beatty, L. Ilsedore Cleeves, Karen A. Collins, Jennifer A. Johnson, Marshall C. Johnson, Michael B. Lund, Clara E. Martínez-Vázquez, Melissa K. Ness, Joseph E. Rodriguez, Robert Siverd, Daniel J. Stevens, Steven Villanueva, Carl Ziegler
The Multiband Imaging Survey For High-Alpha Planets (Mishaps). I. Preliminary Constraints On The Occurrence Rate Of Hot Jupiters In 47 Tucanae, Alison L. Crisp, Jonas Klüter, Marz L. Newman, Matthew T. Penny, Thomas G. Beatty, L. Ilsedore Cleeves, Karen A. Collins, Jennifer A. Johnson, Marshall C. Johnson, Michael B. Lund, Clara E. Martínez-Vázquez, Melissa K. Ness, Joseph E. Rodriguez, Robert Siverd, Daniel J. Stevens, Steven Villanueva, Carl Ziegler
Faculty Publications
The first generation of transiting planet searches in globular clusters yielded no detections, and in hindsight only placed occurrence rate limits slightly higher than the measured occurrence rate in the higher-metallicity Galactic thick disk. To improve these limits, we present the first results of a new wide-field search for transiting hot Jupiters in the globular cluster 47 Tucanae (47 Tuc). We have observed 47 Tuc as part of the Multiband Imaging Survey for High-Alpha PlanetS. Using 24 partial and full nights of observations taken with the Dark Energy Camera on the 4 m Blanco telescope at Cerro-Tololo Interamerican Observatory, we …
Proceedings Of Nordes 2025: Relational Design, Andrew Morrison, Alma Culén, Laurence Habib
Proceedings Of Nordes 2025: Relational Design, Andrew Morrison, Alma Culén, Laurence Habib
DRS Conference Volumes
This volume is the proceedings of the 11th biennial Nordes conference, hosted by OsloMet - Oslo Metropolitan University, 6 – 8 August 2025. All contributions relate in different ways to the overall theme, ‘Relational Design’.
Yo Soy Minnesota: Bridging Health Equity Gaps With Culturally And Linguistically Inclusive Resources For Hispanics In Central Minnesota, Liz Damaris Vincente Berrios
Yo Soy Minnesota: Bridging Health Equity Gaps With Culturally And Linguistically Inclusive Resources For Hispanics In Central Minnesota, Liz Damaris Vincente Berrios
DNP Projects
Health disparities are preventable yet persist due to systemic inequities in social, economic, and healthcare structures. Rooted in historical injustices and social determinants of health, these disparities disproportionately impact minority communities, including Hispanics in Central Minnesota. Barriers such as limited English proficiency (LEP), provider biases, and inadequate health literacy further exacerbate inequitable health outcomes. Culturally and Linguistically Appropriate Services (CLAS) offer a modifiable solution to mitigate these disparities by ensuring healthcare resources align with diverse beliefs, practices, and linguistic needs. This project focuses on CLAS as a modifiable factor affecting Hispanics in Central Minnesota and explores the impact of "Yo …
Artificial Ignorance: Understanding The Role Of Ai In Modern Agnotology, Amit Ray, Michael Nolan
Artificial Ignorance: Understanding The Role Of Ai In Modern Agnotology, Amit Ray, Michael Nolan
Articles
This paper explores the concept of agnotology, the deliberate production of ignorance, within the context of modern scientific endeavors, particularly in the corporate and technological sectors. It examines how industries use various tactics to manipulate public understanding of scientific issues, often to protect profits and limit liability. The rise of private sector funding and the increasing reliance on technologies like AI and machine learning have exacerbated this process by making scientific inquiry more opaque and less accountable. Ultimately, we argue that as knowledge production becomes more entangled with corporate interests and technological systems, traditional methods of oversight and regulation are …
Optimization Of Light Spectrum During The Early Grow-Out Of Caribbean Corals, Liam A. Abrams
Optimization Of Light Spectrum During The Early Grow-Out Of Caribbean Corals, Liam A. Abrams
All HCAS Student Capstones, Theses, and Dissertations
For at least half a century, numerous direct and indirect anthropogenic stressors have led to the decline of coral populations globally. To minimize this decline and preserve genetic diversity, land-based nurseries have been sexually propagating corals to repopulate reefs. While the techniques to induce corals to spawn and rear their larvae are relatively well-established, the grow-out, i.e. rearing from newly settled to a size suitable for outplanting, remains yet to be fully optimized. Specifically, light spectrum, food quantity and quality and algal control require optimization. This study investigated the post-settlement survival and growth of the Caribbean reef building corals Colpophyllia …
Dyadic And Multiparty Turn-Taking In Two Deaf Preschool Classrooms, Savannah Tellander
Dyadic And Multiparty Turn-Taking In Two Deaf Preschool Classrooms, Savannah Tellander
Theses
Conversational turn-taking skills are needed to succeed in most conversational interactions. Timing of turn-taking is crucial for young deaf signers, who need early, accessible, and consistent input in a signed and/or spoken language. For deaf children who acquire a language in either modality, they must acquire appropriate turn-taking skills. Without these abilities, children may miss critical language input, and in a cascading effect–they may miss opportunities both for input (and thus new knowledge) and expressive language. In addition to documenting deaf children’s turn-taking skills across development, it is important to also document timing data for further understanding of cognitive language …
Alternative To The Statistical Mass Confusion Of Testing For "No Effect", Josh L Morgan
Alternative To The Statistical Mass Confusion Of Testing For "No Effect", Josh L Morgan
2020-Current year OA Pubs
In cell biology, statistical analysis means testing the hypothesis that there was no effect. This weak form of hypothesis testing neglects effect size, is universally misinterpreted, and is disastrously prone to error when combined with high-throughput cell biology. The solution is for analysis of measurements to start and end with an interpretation of effect size. In this manuscript, I walk through some of the common critiques of significance testing and how they relate to experimental cell biology. I argue that careful consideration of effect size should be returned to its central position in the planning and discussion of cell biological …
An Ethanol-Induced Loss Of The Lipid Droplet-Associated Segregase Vcp/P97 Leads To Hepatic Steatosis, Sandhya Sen, Shaun Weller, Ryan J Schulze, Donglin Ding, Carol A Casey, Conrad Weihl, Mark A Mcniven
An Ethanol-Induced Loss Of The Lipid Droplet-Associated Segregase Vcp/P97 Leads To Hepatic Steatosis, Sandhya Sen, Shaun Weller, Ryan J Schulze, Donglin Ding, Carol A Casey, Conrad Weihl, Mark A Mcniven
2020-Current year OA Pubs
The liver stores substantial numbers of neutral lipid organelles termed lipid droplets (LDs) that accumulate within hepatocytes in response to chronic ethanol (EtOH) consumption leading to hepatic steatosis. Mass spectrometry analysis of LDs isolated from EtOH-damaged rat livers revealed a substantial reduction in the valosin-containing protein ATPase (VCP/p97) that acts to remove targeted proteins from cellular membranes for degradation. Experimental disruption of VCP function resulted in an increase in LD content in hepatocytes and mouse livers along with a marked increase in LD-associated hydroxysteroid dehydrogenase (HSD17β13) known to contribute to hepatic steatosis. Surprisingly, treatment of hepatocytes with the proteasome inhibitor …
Long-Term Follow-Up Of Left Atrial Appendage Exclusion: Results Of The V-Clip Multi-Center Post-Market Study, Elias Zias, Katherine G Phillips, Marc Gerdisch, Scott Johnson, Ahmed El-Eshmawi, Kenneth Saum, Michael Moront, Michael Kasten, Chanderdeep Singh, Gautam Bhatia, Hiroo Takayama, Ralph Damiano
Long-Term Follow-Up Of Left Atrial Appendage Exclusion: Results Of The V-Clip Multi-Center Post-Market Study, Elias Zias, Katherine G Phillips, Marc Gerdisch, Scott Johnson, Ahmed El-Eshmawi, Kenneth Saum, Michael Moront, Michael Kasten, Chanderdeep Singh, Gautam Bhatia, Hiroo Takayama, Ralph Damiano
2020-Current year OA Pubs
No abstract provided.
How Much Variance Exists Among Published Definitions Of Proximal Junctional Kyphosis? A Retrospective Cohort Study Of Adult Spinal Deformity, Tim T Bui, Karan Joseph, Alexander T Yahanda, Samuel Vogl, Miguel Ruiz-Cardozo, Camilo A Molina
How Much Variance Exists Among Published Definitions Of Proximal Junctional Kyphosis? A Retrospective Cohort Study Of Adult Spinal Deformity, Tim T Bui, Karan Joseph, Alexander T Yahanda, Samuel Vogl, Miguel Ruiz-Cardozo, Camilo A Molina
2020-Current year OA Pubs
No abstract provided.
My A-T Pack: A Qualitative Study Of The Utility, Acceptability, Design, And Content Of A Family-Designed And Owned Information Pack Relevant To The Lives Of Children And Young People Living With Ataxia Telangiectasia, Lisa Bunn, Joanne Paton
My A-T Pack: A Qualitative Study Of The Utility, Acceptability, Design, And Content Of A Family-Designed And Owned Information Pack Relevant To The Lives Of Children And Young People Living With Ataxia Telangiectasia, Lisa Bunn, Joanne Paton
School of Health Professions
BackgroundAtaxia Telangiectasia (A-T) is a rare genetic and progressive condition, primarily affecting the neurological, immunological, and pulmonary systems. In the absence of a cure, people living with A-T require co-ordinated multidisciplinary care to manage their complex needs. This often leads to families working with a range of different professionals and feeling burdened by the amount of information and coordination of care that they manage.With the aim to inform the co-production of a family-owned healthcare pack to promote person-centered care and self-management, this study explored the views of children with A-T and parents of children and young people with A-T about …