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Articles 70771 - 70800 of 1737585
Full-Text Articles in Entire DC Network
Exploring Parameter-Efficient Fine-Tuning Techniques For Code Generation With Large Language Models, Martin Weyssow, Xin Zhou, Kisub Kim, David Lo, Houari A. Sahraoui
Exploring Parameter-Efficient Fine-Tuning Techniques For Code Generation With Large Language Models, Martin Weyssow, Xin Zhou, Kisub Kim, David Lo, Houari A. Sahraoui
Research Collection School Of Computing and Information Systems
Large language models (LLMs) demonstrate impressive capabilities to generate accurate code snippets given natural language intents in a zero-shot manner, i.e., without the need for specific fine-tuning. While prior studies have highlighted the advantages of fine-tuning LLMs, this process incurs high computational costs, making it impractical in resource-scarce environments, particularly for models with billions of parameters. To address these challenges, previous research explored in-context learning (ICL) and retrieval-augmented generation (RAG) as strategies to guide the LLM generative process with task-specific prompt examples. However, ICL and RAG introduce inconveniences, such as the need for designing contextually relevant prompts and the absence …
Ponzilens+: Visualizing Bytecode Actions For Smart Ponzi Scheme Identification, Xiaolin Wen, Tai D. Nguyen, Shaolun Ruan, Qiaomu Shen, Jun Sun, Feida Zhu, Yong Wang
Ponzilens+: Visualizing Bytecode Actions For Smart Ponzi Scheme Identification, Xiaolin Wen, Tai D. Nguyen, Shaolun Ruan, Qiaomu Shen, Jun Sun, Feida Zhu, Yong Wang
Research Collection School Of Computing and Information Systems
With the prevalence of smart contracts, smart Ponzi schemes have become a common fraud on blockchain and have caused significant financial loss to cryptocurrency investors in the past few years. Despite the critical importance of detecting smart Ponzi schemes, a reliable and transparent identification approach adaptive to various smart Ponzi schemes is still missing. To fill the research gap, we first extract semantic-meaningful actions to represent the execution behaviors specified in smart contract bytecodes, which are derived from a literature review and in-depth interviews with domain experts. We then propose PonziLens+, a novel visual analytic approach that provides an intuitive …
Managing Rumors On Electronic Interaction Platforms: How Management Responses Affect Investor Reaction, Runyu Wang, Zili Zhang, Keng Siau, Ziqiong Zhang
Managing Rumors On Electronic Interaction Platforms: How Management Responses Affect Investor Reaction, Runyu Wang, Zili Zhang, Keng Siau, Ziqiong Zhang
Research Collection School Of Computing and Information Systems
This study investigates how listed firms respond to investors’ rumor-related inquiries and examines the impact of these responses on investor reactions, as indicated by subsequent daily abnormal stock returns (ARs). Using a unique dataset of question-and-answer (Q&A) interactions from China’s major e-interaction platforms, established by the stock exchanges, our study provides insights into regulated firm-investor communications in a structured Q&A setting. Unlike informal social media channels, these platforms enable official responses from firm representatives, typically board secretaries, under direct regulatory oversight. By analyzing rumor-related Q&A pairs with regression models and several robustness checks, we find that firms can benefit from …
Shortcuts Everywhere And Nowhere: Exploring Multi-Trigger Backdoor Attacks, Yige Li, Jiabo He, Hanxun Huang, Jun Sun, Xingjun Ma, Yu-Gang Jiang
Shortcuts Everywhere And Nowhere: Exploring Multi-Trigger Backdoor Attacks, Yige Li, Jiabo He, Hanxun Huang, Jun Sun, Xingjun Ma, Yu-Gang Jiang
Research Collection School Of Computing and Information Systems
Backdoor attacks have become a significant threat to the pre-training and deployment of deep neural networks (DNNs). Although numerous methods for detecting and mitigating backdoor attacks have been proposed, most rely on identifying and eliminating the “shortcut” created by the backdoor, which links a specific source class to a target class. However, these approaches can be easily circumvented by designing multiple backdoor triggers that create shortcuts everywhere and therefore nowhere specific. In this study, we explore the concept of Multi-Trigger Backdoor Attacks (MTBAs), where multiple adversaries leverage different types of triggers to poison the same dataset. By proposing and investigating …
Robface: A Test Suite For Efficient Robustness Evaluation Of Face Recognition Systems, Ruihan Zhang, Jun Sun
Robface: A Test Suite For Efficient Robustness Evaluation Of Face Recognition Systems, Ruihan Zhang, Jun Sun
Research Collection School Of Computing and Information Systems
Face recognition is a widely used authentication technology in practice, where robustness is required. It is thus essential to have an efficient and easy-to-use method for evaluating the robustness of (possibly third-party) trained face recognition systems. Existing approaches to evaluating the robustness of face recognition systems are either based on empirical evaluation (e.g., measuring attacking success rate using state-of-the-art attacking methods) or formal analysis (e.g., measuring the Lipschitz constant). While the former demands significant user efforts and expertise, the latter is extremely time-consuming. In pursuit of a comprehensive, efficient, easy-to-use, and scalable estimation of the robustness of face recognition systems, …
Bridging The Digital Skills Gap: A Comparative Study Of Employability Readiness Among Tourism Students And Professionals In Malaysia, Asif Khurshid Mian, Fraz Arshed Butt, Omar Sajid
Bridging The Digital Skills Gap: A Comparative Study Of Employability Readiness Among Tourism Students And Professionals In Malaysia, Asif Khurshid Mian, Fraz Arshed Butt, Omar Sajid
Journal of Global Hospitality and Tourism
The increasing digitalisation of the tourism industry has introduced new expectations for workforce competencies, particularly in developing economies like Malaysia. The present study investigates how three core digital competencies, i.e. digital literacy, platform/tool awareness, and technology readiness, influence employability readiness among two key groups including final-year tourism students and in-service professionals. Drawing on Human Capital Theory and the Technology Readiness Index, the research applies Partial Least Squares Structural Equation Modelling (PLS-SEM) to examine 350 responses collected through purposive sampling. Results confirm that all three competencies positively influence employability readiness, with platform/tool awareness exerting the strongest effect. Multi-group analysis reveals that …
Applying The Synergy Of Experience Accounting And Service Dominant Logic To Rank Customer Experiences In The Mainstream Cruising, Ganna Demydyuk, Mats Carlbäck
Applying The Synergy Of Experience Accounting And Service Dominant Logic To Rank Customer Experiences In The Mainstream Cruising, Ganna Demydyuk, Mats Carlbäck
Journal of Global Hospitality and Tourism
This study analyzes how service-related experiences influence customer satisfaction and perceived value for money in the cruise industry. By integrating Service-Dominant Logic (S-D-L) and Experience Accounting (EA), it aims to support the development of customer-centric performance systems for managerial decision making in the all-inclusive hospitality sector. This is the first empirical study to merge data from three perspectives in service-for-service exchanges: customer review ratings from online platforms, ship-level operational characteristics, and financial metrics from corporate reports. This integrated approach allows for a holistic evaluation of the service ecosystem and cocreation of value onboard cruise ships. A quantitative analysis was conducted …
Nurses’ Knowledge About Assisted Reproductive Methods And Their Awareness About It In Potential Immune-Related Outcomes Of Conceived Children, Salma Abd-Elatty Moawed, Abdallah Ahmed Said
Nurses’ Knowledge About Assisted Reproductive Methods And Their Awareness About It In Potential Immune-Related Outcomes Of Conceived Children, Salma Abd-Elatty Moawed, Abdallah Ahmed Said
Nursing
Abstract A rising worldwide health concern, infertility is impacted by a number of environmental and lifestyle factors. With cutting-edge methods like intrauterine insemination, intracytoplasmic sperm injection, and in vitro fertilization, assisted reproductive technology gives infertile couples hope. Because they provide clinical care, education, and emotional support before, during, and after assisted reproductive technology procedures, nurses are essential to its success. The purpose of this study is to assess nurses’ knowledge and awareness about assisted reproductive methods and the immune outcomes among the resulting children. A structured interview questionnaire will be used to gather data from 130 nurses as part of …
Blending Informing Literacy And Visual Literacy: Instructional Vignettes In Art, Architecture, And Design, Stephanie Beene, Sara Schumacher, Dana Statton Thompson, Mary Wegmann
Blending Informing Literacy And Visual Literacy: Instructional Vignettes In Art, Architecture, And Design, Stephanie Beene, Sara Schumacher, Dana Statton Thompson, Mary Wegmann
University Libraries & Learning Sciences Faculty and Staff Publications
The ACRL Framework for Visual Literacy in Higher Education (Framework for Visual Literacy), based on empirical research into the trends, opportunities, and challenges facing the field of visual literacy in the twenty-first century,1 was codified in April 2022 and is an adaptable document to help learners grow their visual literacy competencies. In this chapter, written by four of the task force members charged with the creation of the Framework for Visual Literacy, we examine the relationship between the four themes in the Framework for Visual Literacy and the six frames of the ACRL Framework for Information Literacy for Higher Education …
Neutrosophic-Based Cephalometric Analysis For Egyptian Population Using Novel Software, Nagham Ahmed Abdelmegeed, Amal F.Abdel-Gawad, Mohamed Alaa Fahmy El-Ghamry
Neutrosophic-Based Cephalometric Analysis For Egyptian Population Using Novel Software, Nagham Ahmed Abdelmegeed, Amal F.Abdel-Gawad, Mohamed Alaa Fahmy El-Ghamry
Neutrosophic Sets and Systems
No abstract provided.
Optimizing Fire Detection In Remote Sensing Imagery For Edge Devices: A Quantization-Enhanced Hybrid Deep Learning Model, Syed Muhammad Salman Bukhari, Nadia Dahmani, Sujan Gyawali, Muhammad Hamza Zafar, Filippo Sanfilippo, Kiran Raja
Optimizing Fire Detection In Remote Sensing Imagery For Edge Devices: A Quantization-Enhanced Hybrid Deep Learning Model, Syed Muhammad Salman Bukhari, Nadia Dahmani, Sujan Gyawali, Muhammad Hamza Zafar, Filippo Sanfilippo, Kiran Raja
All Works
Wildfires are increasing in frequency and severity, presenting critical challenges for timely detection and response, particularly in remote or resource-limited environments. This study introduces the Inception-ResNet Transformer with Quantization (IRTQ), a novel hybrid deep learning (DL) framework that integrates multi-scale feature extraction with global attention and advanced quantization. The proposed model is specifically optimized for edge deployment on platforms such as unmanned aerial vehicles (UAVs), offering a unique combination of high accuracy, low latency, and compact memory footprint. The IRTQ model achieves 98.9% accuracy across diverse datasets and shows strong generalization through cross-dataset validation. Quantization significantly reduces the parameter count …
Development Of The Negative Attitudes Toward Nonbinary Individuals Scale, Jenna Sue Lehmann
Development Of The Negative Attitudes Toward Nonbinary Individuals Scale, Jenna Sue Lehmann
Tennessee State University Alumni Theses and Dissertations
Research within the field of psychology examining the experiences of transgender individuals and prejudice toward transgender individuals has increased in recent history alongside the conscious awareness of transgender individuals within the United States. The research that has been conducted has primarily focused on transgender individuals broadly as a group on binary transgender individuals. As, such measures of prejudice toward these groups have been developed and validated. Although the study of nonbinary experiences and prejudice is developing, there has been no extant measure of prejudice toward nonbinary individuals specifically. A measure of prejudice toward this group is needed to (1) examine …
I Am Scared Too: A Qualitative Study On The Influential Factors On The Fear Of Childbirth In Black Women, Imani Rivers
I Am Scared Too: A Qualitative Study On The Influential Factors On The Fear Of Childbirth In Black Women, Imani Rivers
Tennessee State University Alumni Theses and Dissertations
Pregnancy and childbirth can evoke a range of emotions, including happiness, frustration, and fear. While some worry during pregnancy is expected, heightened and persistent fear can negatively impact a woman’s mental and physical health. Despite this, fear of childbirth remains underexplored, particularly in the context of Black women’s experiences. Existing literature lacks focus on the contextual and systemic factors contributing to this fear, creating a significant research gap (Reissig et al., 2021). Black women in the United States are disproportionately affected by medical mistreatment, often experiencing dismissal and silencing in clinical settings—an issue frequently rooted in implicit bias and racial …
Lung Injury Risk Curves From Behind Armor Blunt Trauma Using A Live Swine Model, Narayan Yoganandan, Lewis Somberg, Danielle Wilson, Alok Shah, Jared Michael Koser, Brian D. Stemper, Valeta Carol Chancey, Joseph Mcentire
Lung Injury Risk Curves From Behind Armor Blunt Trauma Using A Live Swine Model, Narayan Yoganandan, Lewis Somberg, Danielle Wilson, Alok Shah, Jared Michael Koser, Brian D. Stemper, Valeta Carol Chancey, Joseph Mcentire
Biomedical Engineering Faculty Research and Publications
Introduction
From structural, anatomical, and functional perspectives, components of the thoracoabdominal region are heterogeneous and physiologically and functionally different. Although their tolerances to injury are expected to be different, the current Roma Plastilina No. 1 clay penetration criterion for behind armor blunt trauma (BABT) is not specific to the body region. It is important to develop regional injury criteria to ensure its specificity. The objective of the study is to conduct impact tests on the lung region using a live animal model and develop injury risk curves using velocity and deflection metrics via parametric survival analysis.
Materials and Methods
Live …
Categorial Declinations & Democracy, Brenner M. Fissell
Categorial Declinations & Democracy, Brenner M. Fissell
Faculty Publications
The most contentious action taken by reform prosecutors has been the issuance of categorical declination policies. Opponents decry this as bureaucratic nullification of democratically enacted offenses, while the prosecutors themselves counter that they are responding to the will of their local electorate. Democracy claims, it appears, have taken center stage in this debate, and they are deployed by both sides. How should we think about democracy and categorical declinations? The most comprehensive scholarly work on this subject is a 2021 article by Professor Kerrel Murray. In this essay, I hope to continue the work begun by Murray, offering additional insights …
Against Activist Cooperation Agreements, Jennifer O'Hare
Against Activist Cooperation Agreements, Jennifer O'Hare
Faculty Publications
Shareholder activism is at record levels. In a typical campaign, the activist threatens to launch a proxy fight unless the board of directors agrees to take certain actions to increase shareholder value, such as selling off company assets or replacing the CEO. Increasingly, however, there are no proxy fights. Instead, the activist and the board, behind closed doors, quickly agree to settle. The activist withdraws the proxy fight threat, and, in return, the board appoints individuals designated by the activist to sit on the company board. This "Cooperation Agreement" allows the incumbent di- rectors to keep their positions and allows …
Clinical Uptake Of An Antigen-Based Approach To Membranous Nephropathy: A Survey Of General Nephrologists And Glomerular Disease Experts., Eibhlin Goggins, Andrew Delaat, Bryce Barr, Jonathan Taliercio, Ali Mehdi, Georges Nakhoul, Brendan Bowman, Corey Cavanaugh
Clinical Uptake Of An Antigen-Based Approach To Membranous Nephropathy: A Survey Of General Nephrologists And Glomerular Disease Experts., Eibhlin Goggins, Andrew Delaat, Bryce Barr, Jonathan Taliercio, Ali Mehdi, Georges Nakhoul, Brendan Bowman, Corey Cavanaugh
Ambulatory and Primary Care Articles
BACKGROUND: In recent years, there has been an emergence of new antigens discovered in membranous nephropathy (MN). Whether these antigens have impacted the approach to, and management of, MN patients undertaken by nephrologists is still unclear.
METHODS: We conducted a cross-sectional international survey pertaining to 13 antigens recently discovered in MN. The survey was distributed by the National Kidney Foundation, direct emails, and social media.
RESULT: PLA2R, THSD7A, NELL1, and EXT1/2 testing were readily available while the most common response for other antigen testing was 'Not Performed' or 'Unknown'. All respondents had tested for or treated PLA2R-positive MN. Of 79 …
Table Of Contents, Editorial Board, Law School Faculty And Administration, Advisory Board, Advisory Council, Sponsors, Unlv Gaming Law Journal University Of Nevada, Las Vegas -- William S. Boyd School Of Law
Table Of Contents, Editorial Board, Law School Faculty And Administration, Advisory Board, Advisory Council, Sponsors, Unlv Gaming Law Journal University Of Nevada, Las Vegas -- William S. Boyd School Of Law
UNLV Gaming Law Journal
No abstract provided.
Skill Gaming, Pooled Prize Money, And Minor League Professional Tennis, Ryan Rodenberg, Seth Richey
Skill Gaming, Pooled Prize Money, And Minor League Professional Tennis, Ryan Rodenberg, Seth Richey
UNLV Gaming Law Journal
No abstract provided.
Crazy Rich Asians At What Cost? The Role Of Target Marketing In Perpetuating Problem Gambling In Asian Communities, Jana Marquez
Crazy Rich Asians At What Cost? The Role Of Target Marketing In Perpetuating Problem Gambling In Asian Communities, Jana Marquez
UNLV Gaming Law Journal
No abstract provided.
The House Always Learns: Integrating Ai Into Las Vegas Casino Surveillance And The Laws Behind The Lens, Taylor Dixon
The House Always Learns: Integrating Ai Into Las Vegas Casino Surveillance And The Laws Behind The Lens, Taylor Dixon
UNLV Gaming Law Journal
No abstract provided.
Scientific Multimodal Summarization : Integrating Knowledge Across Textual, Visual And Auditory Content, Zusheng Tan
Scientific Multimodal Summarization : Integrating Knowledge Across Textual, Visual And Auditory Content, Zusheng Tan
Lingnan Theses (MPhil & PhD)
As scientific publications increasingly incorporate multimodal content, ranging from textual descriptions to figures, tables, presentation videos, and audio, there is a growing need for summarization systems that can effectively process and integrate information across these diverse modalities.
This work presents a comprehensive exploration of Scientific Multimodal Summarization, introducing a series of novel architectures and datasets aimed at advancing this emerging field. 1): We begin by introducing CMT-Sum, which integrates multimodal scientific source content (i.e., primarily paper text and figures) to generate high-quality textual summaries and identify representative graphical abstracts. We refer to this task as Scientific Multimodal Summarization with …
Wind Turbine Rotor Design Using High-Fidelity Aerostructural Optimization, Marco Mangano, Sicheng He, Yingqian Liao, Denis-Gabriel Caprace, Andrew Ning, Joaquim R. R. A. Martins
Wind Turbine Rotor Design Using High-Fidelity Aerostructural Optimization, Marco Mangano, Sicheng He, Yingqian Liao, Denis-Gabriel Caprace, Andrew Ning, Joaquim R. R. A. Martins
Faculty Publications
Large wind turbines yield more energy but demand careful aeroelastic blade design. Coupled multiphysics design strategies can reduce wind energy costs exploiting fluid-structure interactions. This work presents the first high-fidelity aerostructural optimization study of a large wind turbine rotor.We use blade-resolved fluid dynamics and structural solvers in a monolithic gradient-based optimization framework to explore steady-state torque and blade mass trade-offs. The coupled-adjoint approach computes gradients efficiently, enabling the optimization of over 100 structural and geometric parameters simultaneously. Our optimization study modifies a DTU 10 MW benchmark with a simplified structure and isotropic material properties. The tightly coupled optimizations increase torque …
A Metabolomics Study Of Cardiac Dysfunction In Hyperglycemia: Findings From The Atherosclerosis Risk In Communities (Aric) Study And The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Yilin Yoshida, Ngoc Quynh Nguyen, Eun Hye Moon, Casey Rebholz, Hicham Skali, Victoria Arthur, Justin B Echouffo-Tcheugui, Christie Ballantyne, Elizabeth Selvin, Amil Shah, Robert Kaplan, Carlos J Rodriguez, Qibin Qi, Susan Cheng, Bing Yu
A Metabolomics Study Of Cardiac Dysfunction In Hyperglycemia: Findings From The Atherosclerosis Risk In Communities (Aric) Study And The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Yilin Yoshida, Ngoc Quynh Nguyen, Eun Hye Moon, Casey Rebholz, Hicham Skali, Victoria Arthur, Justin B Echouffo-Tcheugui, Christie Ballantyne, Elizabeth Selvin, Amil Shah, Robert Kaplan, Carlos J Rodriguez, Qibin Qi, Susan Cheng, Bing Yu
Faculty, Staff and Student Publications
Objective: Hyperglycemic states (prediabetes and diabetes) are associated with heart failure (HF) risk. We aimed to identify distinct metabolites for subclinical cardiac dysfunction, a precursor of HF, in hyperglycemic or euglycemic individuals.
Research design and methods: We conducted cross-sectional and prospective analyses of 2,492 HF-free participants from the Atherosclerosis Risk in Communities (ARIC) study visit 5, 2011-2013. A total of 1,297 participants were hyperglycemic (assessed on the basis of hemoglobin A1c >5.7%, fasting glucose >100 mg/dL, use of diabetes medication, or diagnosis), and 1,195 were euglycemic. We used logistic regression for analysis of association between 790 metabolites and cardiac dysfunction, …
A Consensus Guide To Preclinical Indirect Calorimetry Experiments, Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad, Johan Auwerx, Julio E Ayala, Joseph A Baur, Stefania Carobbio, Gary A Churchill, Morten Dall, Rafael De Cabo, Jose Donato, Nathalia R V Dragano, Carol F Elias, Anthony W Ferrante, Brian N Finck, Jose E Galgani, Zachary Gerhart-Hines, Laurie J Goodyear, Justin L Grobe, Rana K Gupta, Kirk M Habegger, Sean M Hartig, Andrea L Hevener, Steven B Heymsfield, Corey D Holman, Martin Hrabě De Angelis, David E James, Lawrence Kazak, Jae Bum Kim, Martin Klingenspor, Xingxing Kong, Sander Kooijman, Louise Lantier, K C Kent Lloyd, James C Lo, Irfan J Lodhi, Paul S Maclean, Owen P Mcguinness, Gema Medina-Gómez, Raghavendra G Mirmira, Christopher D Morrison, Gregory J Morton, Timo D Müller, Yoshihiro Ogawa, David Pajuelo-Reguera, Matthew J Potthoff, Nathan Qi, Marc L Reitman, Patrick C N Rensen, Jan Rozman, Jennifer M Rutkowsky, Kei Sakamoto, Philipp E Scherer, Gary J Schwartz, Radislav Sedlacek, Mohammed Selloum, Saame Raza Shaikh, Shuai Chen, Gerald I Shulman, Vojtěch Škop, Alexander A Soukas, John R Speakman, Bruce M Spiegelman, Gregory R Steinberg, Katrin J Svensson, John P Thyfault, Tony Tiganis, Paul M Titchenell, Nigel Turner, Licio A Velloso, Antonio Vidal-Puig, Christopher S Ward, Ashley S Williams, Christian Wolfrum, Allison W Xu, Ying Xu, Juleen R Zierath, International Indirect Calorimetry Consensus Committee (Iiccc)
A Consensus Guide To Preclinical Indirect Calorimetry Experiments, Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad, Johan Auwerx, Julio E Ayala, Joseph A Baur, Stefania Carobbio, Gary A Churchill, Morten Dall, Rafael De Cabo, Jose Donato, Nathalia R V Dragano, Carol F Elias, Anthony W Ferrante, Brian N Finck, Jose E Galgani, Zachary Gerhart-Hines, Laurie J Goodyear, Justin L Grobe, Rana K Gupta, Kirk M Habegger, Sean M Hartig, Andrea L Hevener, Steven B Heymsfield, Corey D Holman, Martin Hrabě De Angelis, David E James, Lawrence Kazak, Jae Bum Kim, Martin Klingenspor, Xingxing Kong, Sander Kooijman, Louise Lantier, K C Kent Lloyd, James C Lo, Irfan J Lodhi, Paul S Maclean, Owen P Mcguinness, Gema Medina-Gómez, Raghavendra G Mirmira, Christopher D Morrison, Gregory J Morton, Timo D Müller, Yoshihiro Ogawa, David Pajuelo-Reguera, Matthew J Potthoff, Nathan Qi, Marc L Reitman, Patrick C N Rensen, Jan Rozman, Jennifer M Rutkowsky, Kei Sakamoto, Philipp E Scherer, Gary J Schwartz, Radislav Sedlacek, Mohammed Selloum, Saame Raza Shaikh, Shuai Chen, Gerald I Shulman, Vojtěch Škop, Alexander A Soukas, John R Speakman, Bruce M Spiegelman, Gregory R Steinberg, Katrin J Svensson, John P Thyfault, Tony Tiganis, Paul M Titchenell, Nigel Turner, Licio A Velloso, Antonio Vidal-Puig, Christopher S Ward, Ashley S Williams, Christian Wolfrum, Allison W Xu, Ying Xu, Juleen R Zierath, International Indirect Calorimetry Consensus Committee (Iiccc)
Children’s Nutrition Research Center Staff Publications
Understanding the complex factors influencing mammalian metabolism and body weight homeostasis is a long-standing challenge requiring knowledge of energy intake, absorption and expenditure. Using measurements of respiratory gas exchange, indirect calorimetry can provide non-invasive estimates of whole-body energy expenditure. However, inconsistent measurement units and flawed data normalization methods have slowed progress in this field. This guide aims to establish consensus standards to unify indirect calorimetry experiments and their analysis for more consistent, meaningful and reproducible results. By establishing community-driven standards, we hope to facilitate data comparison across research datasets. This advance will allow the creation of an in-depth, machine-readable data …
Folliculin Deletion In The Mouse Kidney Results In Cystogenesis Of The Loops Of Henle Via Aberrant Tfeb Activation, Ola Shalaby, Tomoko Ohmori, Koichiro Miike, Shunsuke Tanigawa, Luh Ade Wilan Krisna, Alessia Calcagnì, Andrea Ballabio, Yoshiaki Kubota, Laura S Schmidt, W Marston Linehan, Takaaki Ito, Masaya Baba, Ryuichi Nishinakamura
Folliculin Deletion In The Mouse Kidney Results In Cystogenesis Of The Loops Of Henle Via Aberrant Tfeb Activation, Ola Shalaby, Tomoko Ohmori, Koichiro Miike, Shunsuke Tanigawa, Luh Ade Wilan Krisna, Alessia Calcagnì, Andrea Ballabio, Yoshiaki Kubota, Laura S Schmidt, W Marston Linehan, Takaaki Ito, Masaya Baba, Ryuichi Nishinakamura
Duncan NRI Faculty and Staff Publications
The mammalian kidney contains numerous nephrons connected to the collecting ducts, and each nephron consists of a glomerulus, a proximal tubule, the loop of Henle (LoH), and a distal tubule. Folliculin (FLCN) is a causative gene for Birt-Hogg-Dubé syndrome, which is characterized by a variety of manifestations, including renal cysts and cancer. Although deletion of Flcn in the mouse collecting duct and distal nephron leads to cyst formation, its precise role in the entire nephron remains unclear. Herein, nephron-specific Flcn knockout mice exhibited cystogenesis along the entire nephron segments, most prominent in the LoH, preceded by an irregularly shaped lumen …
Current Controversies In Prenatal Diagnosis 2: Conventional Postmortem Examination Remains The Gold Standard For The Anatomical Examination Of Fetal Loss, J Ciaran Hutchinson, Lorraine Potocki, Ignatia B Van Den Veyver
Current Controversies In Prenatal Diagnosis 2: Conventional Postmortem Examination Remains The Gold Standard For The Anatomical Examination Of Fetal Loss, J Ciaran Hutchinson, Lorraine Potocki, Ignatia B Van Den Veyver
Duncan NRI Faculty and Staff Publications
A comprehensive postmortem examination is an essential component of a work-up after stillbirth. Its findings can support accurate counseling of parents about causes and risk of recurrence. It also supports providers' decisions about most appropriate testing and management plans for future pregnancy to prevent recurrence. Informing parents about fetal autopsy and obtaining their consent is challenging, and conducting a fetal autopsy requires expertise that is, not universally available. Newer non-invasive or minimally invasive methods such as postmortem MRI and targeted biopsies can replace or supplement autopsies, but one must recognize that expertise in these methods is likewise not broadly available. …
Diagnostic Yield Of Exome Sequencing For Pregnancies With And Without Fetal Anomalies And For Stillbirth, Roni Zemet, Christian M Parobek, April D Adams, Mohamad Ali Maktabi, Lena Shay, Linyan Meng, Pengfei Liu, Hongzheng Dai, Fan Xia, Christine Eng, Ignatia B Van Den Veyver, Liesbeth Vossaert
Diagnostic Yield Of Exome Sequencing For Pregnancies With And Without Fetal Anomalies And For Stillbirth, Roni Zemet, Christian M Parobek, April D Adams, Mohamad Ali Maktabi, Lena Shay, Linyan Meng, Pengfei Liu, Hongzheng Dai, Fan Xia, Christine Eng, Ignatia B Van Den Veyver, Liesbeth Vossaert
Duncan NRI Faculty and Staff Publications
Objective: Exome sequencing (ES) benefits the genetic work-up for fetuses with structural anomalies, but data on its utility for fetuses without anomalies and stillbirths is more limited. We report our experience with prenatal ES for all three indications.
Method: We retrospectively reviewed results from 344 trio-ES performed for fetuses with structural anomalies (N = 262), stillbirths (N = 39), and fetuses without anomalies (N = 43), many of which had a relevant family history. We classified pathogenic variants (P), likely pathogenic variants (LP), or variants of uncertain significance (VUS) favoring pathogenicity in a gene consistent with the fetal phenotype as …
Evaluation Of Achievement Change In Egypt Using Pirls Data, Harry Anthony Patrinos, Maciej Jakubowski, Tomasz Gajderowicz
Evaluation Of Achievement Change In Egypt Using Pirls Data, Harry Anthony Patrinos, Maciej Jakubowski, Tomasz Gajderowicz
Education Reform Faculty and Graduate Students Publications
This study analyzes Egypt's exceptional reading achievement gains during the COVID-19 school closures, a period when most countries experienced declines. Drawing on data from the 2016 and 2021 Progress in International Reading Literacy Study (PIRLS), we find a 48-point improvement-equivalent to two years of learning-with notable gains among boys. Using Ordinary Least Squares (OLS) and projected trend models, we confirm the significance of this rise. Oaxaca-Blinder decomposition attributes only one-third of the improvement to observed factors. The study finds that Egypt's progress likely reflects systemic reforms, but more research is needed to confirm that.
Advancing U.S. Competitiveness In Agentic Gen Ai: A Strategic Framework For Interoperability And Governance, Satyadhar Joshi
Advancing U.S. Competitiveness In Agentic Gen Ai: A Strategic Framework For Interoperability And Governance, Satyadhar Joshi
Harrisburg University Other Works
Abstract : The rapid evolution of artificial intelligence has given rise to agentic AI systems—autonomous entities capable of perceiving their environment, making decisions, and executing actions with minimal human intervention. This work provides a systematic analysis of agentic AI frameworks, governance models, and implementation strategies. Drawing on a comprehensive review of the literature, we examine the current state of agentic AI technologies, highlight key challenges in governance, security, and ethical oversight, and compare architectural frameworks for responsible deployment. Our results, illustrated through detailed framework comparisons and governance analyses, demonstrate that while agentic AI holds transformative potential across multiple sectors, notable …