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Capacity Of Gum Arabic As Immunomodulator And Antibacterial Agent Against Oral Cavity Periodontopathogen In Diabetes Mellitus Rats With Periodontitis, Tantin Ermawati, Suhartini, Tecky Indriana, Zahreni Hamzah

Journal of Dentomaxillofacial Science

Objective: This study aims to determine the benefits of gum arabic as an immunomodulatory and antibacterial drug therapy in the oral cavity of diabetic mellitus rats.

Material and Methods: Male wistar rats induced by diabetes mellitus accompanied by periodontitis and Gum Arabic therapy.  This study was divided into 5 treatment groups, namely group I (control), group II (diabetes mellitus) and group III (diabetes mellitus and periodontitis with P. gingivalis injection), group IV (diabetes mellitus treated with gum arabic), group V (diabetes mellitus with periodontitis and treated with gum arabic). The parameters studied were TNF-α anti-inflammatory mediators and the number of …

Series Reports From Professor Wei’S Group Of Chongqing University: Advancements In Electrochemical Energy Conversions (2/4): Report 2: High-Performance Water Splitting Electrocatalysts, Ling Zhang, Wang-Yang Wu, Qiu-Yue Hu, Shi-Dan Yang, Li Li, Rui-Jin Liao, Zi-Dong Wei

Journal of Electrochemistry

The unavailability of high-performance and cost-effective electrocatalysts has impeded the large-scale deployment of alkaline water electrolyzers. Professor Zidong Wei’s group has focused on resolving critical challenges in industrial alkaline electrolysis, particularly elucidating hydrogen and oxygen evolution reaction (HER/OER) mechanisms while addressing the persistent activity-stability trade-off. This review summarizes their decade-long progress in developing advanced electrodes, analyzing the origins of sluggish alkaline HER kinetics and OER stability limitations. Professor Wei proposes a unifying “12345 Principle” as an optimization framework. For HER electrocatalysts, they have identified that metal/metal oxide interfaces create synergistic “chimney effect” and “local electric field enhancement effect”, enhancing selective …

Local Electric Fields Coupled With Cl− Fixation Strategy For Improving Seawater Oxygen Reduction Reaction Performance, Yu-Rong Liu, Miao Zhang, Yan-Hui Yu, Ya-Lin Liu, Jing Li, Xiao-Dong Shi, Zhen-Ye Kang, Dao-Xiong Wu, Peng Rao, Ying Liang, Xin-Long Tian

Journal of Electrochemistry

Development of robust electrocatalyst for oxygen reduction reaction (ORR) in a seawater electrolyte is the key to realize seawater electrolyte-based zinc-air batteries (SZABs). Herein, constructing a local electric field coupled with chloride ions (Cl⁻) fixation strategy in dual single-atom catalysts (DSACs) was proposed, and the resultant catalyst delivered considerable ORR performance in a seawater electrolyte, with a high half-wave potential (E_1/2) of 0.868 V and a good maximum power density (Pmax) of 182 mW·cm⁻² in the assembled SZABs, much higher than those of the Pt/C catalyst (E_1/2: 0.846 V; Pmax: 150 mW·cm^{−2 …}

Comparative Assessment Of Malocclusion In The Sagittal Plane Based On Clinical Dental And Skeletal Characteristics, Vyzhenko Yevhenii, Kuroiedova Vira, Halych Liudmila, Makarova Oleksandra

Journal of Dentomaxillofacial Science

ABSTRACT

Objective: The aim of this study was to provide a comparative assessment of sagittal malocclusion based on clinical dental and skeletal characteristics in a sample of the Ukrainian population and to identify cephalometric variables that are contributing factors in the formation of malocclusion in the sagittal plane.

Material and methods: The study included 200 subjects with malocclusion, aged 9–20 years. Clinical sagittal molar occlusion was determined according to Angle’s classification. Skeletal characteristics were classified based on the ANB angle. Cephalometric analysis was performed using cone-beam computed tomography. Statistical analysis was conducted using the Shapiro-Wilk hypothesis test with …

Microtia

Faculty, Staff and Students Publications

No abstract provided.

Scaling Symmetry Of The Hodgkin-Huxley Mathematical Model, Vladimir Valerievich Galanin

Progress in Scale Modeling, an International Journal

A computational method based on the application of a scaling transformation to the Hodgkin-Huxley mathematical model of the biological neuron and its generalizations to the case of various neural systems is proposed. The method makes it possible: 1) to obtain invariants of the scaling transformation of the Hodgkin-Huxley model; 2) to find self-similarity regions corresponding to the modes of neural activity; 3) to determine the conditions for the similarity of models of various types of biological neurons; 4) to reduce the order of the system of differential equations of the Hodgkin-Huxley model for neural systems with synchronous activity. The capabilities …

Collective Dominance Under Scrutiny: Closing The Enforcement Gap Or Complicating Eu Competition Policy?, Miroslava Marinova

Yearbook of Antitrust and Regulatory Studies

This paper examines the European Commission’s Draft Guidelines on Article 102 TFEU, focusing on their treatment of collective dominance in oligopolistic markets. While the Guidelines adopt a structured framework derived from merger control, they fail to address a key challenge specific to Article 102: the need for clear evidentiary standards in retrospective enforcement. The paper argues that parallel conduct by independent firms can, in certain cases, serve as evidence of collective dominance where such behaviour is not rational absent joint market power. However, the Draft Guidelines offer little guidance on how to integrate such conduct into the dominance analysis. This …

Llm-Gaode: Large-Language-Model Augmented Neural Ordinary Differential Equation Network For Video Nystagmography Classification, Shuo Li

Faculty Scholarship

Benign paroxysmal positional vertigo (BPPV), a common type of vertigo with complex etiologies, is traditionally diagnosed using video nystagmography (VNG). Current automated methods lack diagnostic precision owing to subjective interpretation of eye movement characteristics. To address these challenges, we introduce a large language model-augmented Gram-based attentive neural ordinary differential equation (LLM-GAODE), an innovative and data-driven framework integrating eye-tracking technology with a Gram-based attention mechanism and a neural ordinary differential equation network to improve BPPV classification. Furthermore, when the neural network exhibits low confidence in its predictions, an LLM can supplement the process with advanced reasoning in natural language. LLM-GAODE was …

Proceedings Of The Ursinus Colloquium On Liberal Education: Liberal Arts On Offense, Stephanie Mackler, Allison E. Carey, Matt Kozusko, Mark Schneider

Ursinus Colloquium on Liberal Education

About • Liberal Arts on Offense: Introductory Remarks • Questions Posed to the Alumni Panel • Panel Remarks from Session One: Offensive Liberal Arts • List of Participants

Genomic Prediction And Association Mapping Of Early Season Flood Tolerance In Soybean, Caio Canella Vieira, Chengjun Wu, Derrick Harrison, Rafael Marmo, Liliana Florez-Palacios, Andrea Acuna, Daniel Rogers, Samuel B. Fernandes, Igor Fernandes, Grover Shannon, Heng Ye, Henry T. Nguyen

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Flooding has become a major threat to soybean [Glycine max (L.) Merr.] production as the frequency and intensity of extreme precipitations have been increasing due to climate change. While advances have been made in identifying soybean genetic resources and genomic regions associated with mid-season flood tolerance, there is limited understanding of early season flood tolerance at the vegetative growth stages V2/V4. This study aimed to identify genomic regions associated with early season flood tolerance using a diverse panel of 254 soybean accessions, as well as investigate the viability of implementing genomic prediction models for flood tolerance. Field trials were conducted …

Optimal Estimation In A Multicointegrated System, Igor Kheifets, Peter C.B. Phillips

Cowles Foundation Discussion Papers

Optimal estimation is explored in long run relations that are modeled within a semiparametric triangular multicointegrated system. In nonsingular cointegrated systems, where there is no multicointegration, optimal estimation is well understood (Phillips, 1991a). This paper establishes corresponding optimal results for singular systems, thereby accommodating a wide class of multicointegrated nonstationary time series with nonparametric transient dynamics. The optimality and sub-optimality of existing estimators are considered and new optimal estimators of both the cointegrating and multicointegrating coefficients are introduced that are based on spectral regression.

Covid-19 Vaccination Coverage In Al-Qassim District, Iraq: Epidemiological Analysis (2021-2022), Murtadha K. Ibrahiem, Ghanim Aboud Jaber Al-Mola, Rafah Hady Lateef

Hilla University College Journal For Medical Science

Background: Vaccines against COVID-19 have been instrumental in preventing the spread and severity of the disease in the world. In Iraq, coverage and distribution of vaccines across regions have differed.

Objectives: The objective of this study was to assess the coverage of three types of COVID-19 vaccines in Al-Qasim District, Babil Governorate, Iraq, in the years 2021 and 2022.

Materials and Methods: In a retrospective observational study, local health authority vaccination data were utilized. The study population was approximately 310,000 residents of three sub-districts. Monthly data for 2021 and 2022 were included for the quantity of vaccine doses (first and …

Converse Of Ptolemy’S Theorem, Hidefumi Katsuura

Faculty Research, Scholarly, and Creative Activity

In The Almagest, we found the original Ptolemy’s theorem and its proof, and we compared it to “Ptolemy’s theorem” written in two modern geometry textbooks. They are different in that the new ones include the “converse” of the original one. We noticed the hypothesis of the “converse” can be interpreted in two ways. Using this as our motivation, we establish a new theorem related to Ptolemy’s theorem in this note as follows: If four distinct points A, B, C, D are given in the three-dimensional space so that ABC is a triangle, and if |AB||CD|+|AD||BC|=|AC||BD|, then the points A, B, …

Comparison Of Authentic Urine N-Ethylpentedrone Metabolites To Predicted In Silico And In Vitro Human Hepatocyte Metabolism, Gloria Daziani, Omayema Taoussi, Diletta Berardinelli, Giulia Bambagiotti, Marilyn A. Huestis, Francesco P. Busardò, Jeremy Carlier

Institute of Emerging Health Professions Faculty Papers

Synthetic cathinones are the second most common class of substances belonging to the category of new psychoactive substances (NPS). N-ethylpentedrone (NEPD) self-administration was reported, making it important to elucidate its metabolic pathway to improve its detection. NEPD is often taken together with other substances; confidently identifying its intake is important for accurate toxicological analysis and understanding its toxicity. NEPD metabolism was studied following incubation with human hepatocytes and analysis by liquid chromatography-high-resolution mass spectrometry paired with Compound Discoverer software (Thermo Fisher Scientific). Prediction of possible metabolites was performed with the online software GLORYx. In vivo NEPD metabolism was evaluated by …

Prevalence And Distribution Of Neonatal Congenital Malformations In Al-Najaf, Iraq: A Cross-Sectional Analysis Of 2022 Birth Registry Data, Sahar Hassan

Hilla University College Journal For Medical Science

Background: Congenital malformations are among the primary causes of neonatal morbidity and mortality worldwide, imposing significant challenges in regions with limited healthcare resources and high birth rates.

Objectives: The goal of this study is to find out how common and spread-out congenital malformations are among newborns in Al-Najaf, Iraq. The results could have a big effect on how healthcare is provided and improve the health of newborns.

Methods: This descriptive cross-sectional study analyzed birth registry data from five major hospitals in Al-Najaf, Iraq, in 2022. We identified neonates diagnosed with congenital malformations from a total cohort of 37,904 live births. …

Investigation Of Growth Differentiation Factor-15, And Lipid-Based Indices In Assessing Cardiovascular Risk In Overt And Subclinical Hypothyroidism, Arkan Hamed Hatroosh, Mohammed Abdulateef Mohammed Ali, Jalal Abid Ali

Hilla University College Journal For Medical Science

Background: Hypothyroidism, both overt and subclinical, has emerged as a notable contributor to increased cardiovascular disease (CVD) risk. This association is mediated by multifactorial mechanisms, including significant dyslipidemia, heightened oxidative stress, and vascular endothelial dysfunction.

Materials and Methods: A case-control study was conducted at the Specialized Center for Diabetic Endocrinology, Baghdad/Russafa, between October 2024 and January 2025. The study included 130 participants: 35 patients with overt hypothyroidism, 35 with subclinical hypothyroidism, and 60 age-, sex-, and BMI-matched euthyroid controls. Blood samples were collected and processed for analysis of serum GDF-15, and lipid profiles. CRI-I, CRII-I, AIP, and AC were calculated. …

The Function Of Di-Methyl Fumarate In Immunobiochemical And Hematological Changes In Individuals Infected With Entamoeba Histolytica, Saif Mohammed Algebory, Zainab Ali Hussein, Sarah Suliman Mohammed, Alaa Ihsan Saymeh, Hayder Kareem Algabri

Hilla University College Journal For Medical Science

Background: Amebiasis can cause a number of symptoms, from infections that are passed on when someone touches something infected to serious illness.

Objectives: role of DMF on reducing Entamoeba histolytica (E. histolytica) infection.

Materials and Methods: The study involved patients supplying E. histolytica-related symptoms. Diagnoses were confirmed using stool samples, and 10 mL of venous blood was obtained for antioxidant and immunological investigation. Groups: Control (uninfected patients), Normal medication (infected patients on normal medication), and Combination (infected patients getting standard treatment with DMF).

Results: Group 2 and 3 had lower red blood cell and haemoglobin levels than group …

Analyze The Mechanistic Role Of Lox-1 In Cardiovascular Diseases: A Review, Mohammed Algebory, Zainab Ali Hussein, Amira Shamseldin Mohamed Khalafalla, Emaan Mohammed Zina

Hilla University College Journal For Medical Science

Cardiovascular disease (CVD) is a major global health concern that leads to illness and death. One of the primary risk factors for CVD is dyslipidemia, which can cause an elevation of oxidized LDL. Recently, the lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1 receptor), a transmembrane protein found in endothelial cells, platelets, cardiomyocytes, and other cells, has gained attention. LOX- 1 receptors are responsible for recognizing oxLDL, and overactivation can trigger pathways that cause tissue damage, including endothelial dysfunction and apoptosis, process under investigation involves the following: promotion of platelet activation and adhesion to endothelial cells; ADP-mediated aggregation; and the development …

The Concept Of Preeclampsia In Biochemistry: Molecular Mechanisms, Oxidative Stress, And Emerging Biomarkers, Dunia Abbas Khudhair, Ammar Hatem Abdullateef, Abbas Hamza Khudhair

Hilla University College Journal For Medical Science

Preeclampsia is a complex, pregnancy-related hypertension condition that significantly endangers mother and fetal health. While its clinical diagnosis is based on hypertension and proteinuria, its origins lie in a cascade of biochemical and molecular disturbances. This review highlights the central concept of preeclampsia from a biochemical perspective, with emphasis on abnormal placental development, oxidative stress, and endothelial dysfunction. Placental hypoxia and an excess of reactive oxygen species (ROS) are caused by inadequate spiral artery remodeling, which also leads to lipid peroxidation and systemic inflammation. A critical biochemical characteristic is the disparity between anti-antigenic (sFlt-1, sENG) and pro-antigenic (PlGF, VEGF) molecules, …

Age-Dependent Associations Of Etanercept And Methotrexate In Stage Ii And Iii Rheumatoid Arthritis Patients, Saif M. Hassan, Zainab Ali Hussein

Hilla University College Journal For Medical Science

Background: Rheumatoid arthritis (BC) is a complex disease that involves molecular and cellular alterations mediated by endogenous and exogenous factors.

Objectives: This study aimed to determine the osteoblastic and osteoclastic activities at baseline and three months after therapy in RA patients treated with methotrexate (MTX) and Etanercept (ETN).

Methods: investigated the relationship between Etanercept 1 (ETN1) and Methotrexate levels in Rheumatoid arthritis patients positive for cancer antigen 15–3 (CA15-3). This study included 90 patients with stage II and III BC divided into two age groups (25–44 and 45–60 years) and 90 age-matched healthy controls. Serum concentrations of ETN1 and …

Acute Care Of Patients With Moderate Respiratory Distress: Recommendations From An American College Of Emergency Physicians Expert Panel., Christopher W Baugh, Jim F Neuenschwander, Jesslyn Lenox, Jennifer Hoh, Kara Ward, Sara Muramoto, John Casey, Antonio Anzueto, Hajirah Ishaq, Jared Mount, Peter M Deblieux

Ambulatory and Primary Care Articles

INTRODUCTION: Patients with respiratory distress are frequently encountered in the emergency department (ED). Efforts to assess, initiate treatments, and stabilize these patients require a systematic and rapid response. Emergency physicians need a comprehensive and efficient approach for evaluating, treating, and managing patients presenting to the ED with moderate respiratory distress.

METHODS: The American College of Emergency Physicians convened an expert panel of academic and community emergency physicians, critical care specialists, respiratory therapists, hospitalists, and pharmacists to develop and subsequently disseminate consensus recommendations regarding the diagnosis and treatment of patients with moderate respiratory distress presenting to the ED.

RESULTS: A digital …

Digital Color And Aesthetics: A Numerical Performance That Speaks To Presentness, Valeria Federici

Contemporary Aesthetics (Journal Archive)

This article is concerned with digital color’s presentness and ubiquity and the implications of these aspects as reflected in contemporary artistic practices and aesthetics. Taking into consideration the history of color theory, the article explores premises and findings relevant to digital color and its differences with natural color as derived by optical vision. Further, it investigates the relationship between computer and artists, between appearance and experience in the digital realm, and highlights how digital color lies in the very nature of the medium: a numerical language hiding behind a mimetic two-dimensional surface or interface. These aspects are discussed through the …

Early-Life Exposure To Organic Chemical Pollutants As Assessed In Primary Teeth And Cardiometabolic Risk In Mexican American Children: A Pilot Study, Vidya S. Farook, Feroz Akhtar, Rector Arya, Alice Yau, Srinivas Mummidi, Juan Lopez Alvarenga, Alvaro Diaz-Badillo, Roy G. Resendez, John Blangero

Human Genetics Publications

Early-life exposure to organic chemicals (OCs) may influence childhood obesity and associated cardiometabolic risk. These conditions have been shown to disproportionately affect minority populations such as Mexican Americans (MAs). However, information on the impact of organic chemicals on cardiometabolic risk in MA children is limited. Therefore, we conducted a pilot study to assess the extent to which exposure to organic chemicals influences cardiometabolic traits (CMTs) in MA children. We recalled 25 children from a previous study and collected 25 primary teeth from them. Chemical analyses of the teeth were performed using established protocols. Target analytes included acetaminophen (APAP); 3,5,6-trichloro-2-pyridinol (TCPy), …

Growth Plate Skeletal Stem Cells And Their Actions Within The Stem Cell Niche

Faculty, Staff and Student Publications

The growth plate is a specialized cartilage structure near the ends of long bones that orchestrates longitudinal bone growth during fetal and postnatal stages. Within this region reside a dynamic population of growth plate skeletal stem cells (gpSSCs), primarily located in the resting zone, which possess self-renewal and multilineage differentiation capacity. Recent advances in cell-lineage tracing, single-cell transcriptomics, and in vivo functional studies have revealed distinct subpopulations of gpSSCs, which are defined by markers such as parathyroid hormone-related protein (PTHrP), CD73, axis inhibition protein 2 (Axin2), forkhead box protein A2 (FoxA2), and apolipoprotein E (ApoE). These stem cells interact intricately …

"Our River Is Full Of Trash And Many Fish Die" Children's Voices From Pasuruan, Indonesia: Discursive Strategies In Positive Discourse Analysis For Sustainability, Bambang Prastio, Ahsani Maulidina, Agung Rinaldy Malik, Achmad Tantowi Azis

The Qualitative Report

Addressing river pollution and understanding the role of children in environmental conservation are essential for maintaining ecosystem health and sustainability. This study used positive discourse analysis to explore children's discourse about river pollution in Pasuruan, East Java, Indonesia. Data were collected using walk-and talk ethnographic interviews with 15 children aged 7 to 11 years. The findings reveal that these children employed five discursive strategies: (1) nomination: metaphor, comparison, and cultural practices; (2) predication: positive attitude in the forms of disposition and behavior; (3) argumentation: contrast and parallelism; (4) perspectivisation, involving a type of religious representation that includes references to the …

A Not-Quite-Assessment Of Assessing Autoethnography: Ekphrastic Compositions On Quality, Clarity, And (Un)Certainty In Autoethnography, Aaron Hoy

The Qualitative Report

Taking an ekphrastic approach, this essay responds to and reflects on my reading of Assessing Autoethnography: Notes on Analysis, Evaluation, and Craft by Andrew F. Herrmann and Tony E. Adams. It has three parts. First, I summarize the book’s central chapters and discuss their practical uses, especially as prompts for in-progress autoethnographies. Second, using clarity as a point of entry, I explore a tension I felt while reading the book—between the comforting utility of specific criteria and the marginalizing power of criteria themselves. Finally, I share a found poem composed in response to the book and reflect on the impermanent …

Emotion Labor As A Catalyst For Language Teacher Identity Renewal And Well-Being: An Autoethnography, Yasser Aminifard

The Qualitative Report

In this autoethnographic study, I explore how my temporary engagement in emotion labor, triggered by teaching and assessment demands imposed by my university, prompted a renewal of my teaching style and enhanced my well-being. Personal journals supplemented by semi-structured interviews with the university’s vice-chancellor, whose expectations precipitated my emotion labor, served as the primary data sources. Drawing on Engeström’s (2015) activity theory, I analyze the contradictions within my university’s activity system that gave rise to my emotion labor, understood here as the management of the negative emotions and tensions arising from discrepancies between teachers’ professional beliefs and workplace demands (Benesch, …

Airway Abnormalities In Children Operated For Congenital Heart Disease: Clinical Characteristics And Risk Factors From A Case-Control Study, Fatma Al Kindi, Rand Al Harthy, Saif A. Thani, Hamood Al Kindi, Hussain Mohsin

Sultan Qaboos University Medical Journal

Objectives: Congenital heart disease (CHD) is the most common congenital defect, with airway abnormalities (AAs) representing significant comorbidities that contribute to increased morbidity and clinical complexity. This study aimed to identify the most common AAs, associated risk factors, and clinical outcomes in children with CHD. Methods: This case-control study included children aged under 13 years with CHD who underwent cardiothoracic surgery between 1 January 2016 and 31 December 2018 at the National Genetic Centre in Oman. Cases were children with concurrent AAs, while controls were age- and gender-matched children with CHD but without AAs. Results: The prevalence …

A Few Millimeters Of Bone: How Male Supremacists Leverage Scientific Sexism To Reinforce Misogynistic Ideologies, Robin O'Hanlon

Publications and Research

In recent years, male supremacist actors have reinforced their misogynistic worldviews by using narrative strategies centered on authoritative “common sense” and scientific “fact.” This paper presents a thematic narrative analysis of The Incel Wiki and the Wiki4Men, representing the first formal analysis of the wiki for the men’s rights organization A Voice for Men. The analysis indicates male supremacists use techniques including misappropriation of scientific information, manipulation of statistics, and leveraging pseudoscientific information to develop their narrative strategies of supremacy. The most consistent narrative strategies of scientific sexism on the wikis are male victimhood, denial of inequality between men and …

Concrete Material Bank In Japan Toward Co2 Recycling, Masaki Tamura, Takafumi Noguchi

C3 Symposium 2025

Providing excellent performance as a structural material, concrete has long been essential for modern civilization and recognized as a material that will continue to maintain and support the development of human society. Now that recycling of concrete in a completely closed loop has become technically feasible, concrete is being seen in a new light. On the other hands, the huge issues regarding carbon dioxide emissions all of the world are a concern in the construction field as well as in society. To solve this problem, a concept for new Calcium Carbonate Concrete (CCC) is proposed. This paper is focused on …