Digital Commons Network^™

Editorial: Decoding Vascular Aging: Unraveling The Enigma Of Pathological Conditions And Pre-Mature Vascular Aging, Mitra Esfandiarei, Roshanak Rahimian

Pacific Faculty Work

No abstract provided.

The Colby Echo (2025-10-02), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly during the academic year, 1898-present.

Effect Of Establishing A Separate Outpatient Pharmacy Counter On Reducing Waiting Time In Mayapada Hospital, Hanifan Irham, Masyitoh Basabih

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Pharmacy waiting time is one of the quality indicators that affects patient satisfaction in hospitals. One of the various efforts to reduce drug waiting times is adding outpatient pharmacies. This study aims to see whether the addition of pharmacies based on guarantors can reduce drug waiting times for outpatients. This is an observational study with a cross-sectional design. The sample included 11,703 patients who received prescriptions at Mayapada Hospital Bogor outpatient with insurance and private coverage. Data were collected over four months, two months before and two months after the separation of pharmacies. Waiting time data were obtained from the …

The Role Of The Triage Nurse Deployment In Reducing Triage Time In Emergency Department, Ristanti Karina, Masyitoh Basabih

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Emergency Departments (ED) operate under high-pressure conditions where rapid and accurate triage is essential to ensure optimal patient outcomes. This study aimed to evaluate whether the assignment of dedicated triage nurses could reduce triage procedure time in the ED. The study employed an observational cross-sectional design using secondary data extracted from the Hospital Information System (HIS) at XYZ Private Hospital, Bogor. The intervention involved assigning trained triage nurses for each shift starting in June 2024, replacing the previous practice of ad hoc triage by available nurses. The results showed a significant reduction in median triage time from 4 minutes and …

Determinant Factors Of Completeness Of Medical Resume Filling By Doctors At Pesawaran Regional General Hospital, Achmad Deza Farista, Aila Karyus, Abikusno Djamaluddin

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

A medical resume serves as a vital document that compiles essential information related to a patient’s clinical management. In 2019, the completeness rate of medical resume documentation at Pesawaran Regional General Hospital was only 37.4%. This study aimed to identify factors influencing the completeness of medical resume documentation by doctors through a quantitative, cross-sectional design involving 37 inpatient care doctors. Data were collected via questionnaires and direct observation, then analyzed using univariate, bivariate (Chi-Square), and multivariate (Logistic Regression) methods. Observation showed that 56.8% of medical resumes were incomplete. Questionnaire results indicated that 54.1% of respondents had negative perceptions of Standard …

Structural Insights Into Brain Thyroid Hormone Transport Via Mct8 And Oatp1c1, Gaya P Yadav, Theodore G Wensel, Jiansen Jiang, Pengxiang Huang

Faculty, Staff and Students Publications

Adequate delivery of thyroid hormones to the brain is crucial for normal neurological development. MCT8 and OATP1C1, two solute carrier (SLC) transporters, mediate the passage of thyroid hormones across the blood-brain barrier and into the central nervous system. Mutations in MCT8 result in Allan-Herndon-Dudley syndrome (AHDS), an X-linked birth defect characterized by neurodevelopmental impairments and peripheral hyperthyroidism, whereas OATP1C1 deficiency is linked to brain hypometabolism and progressive neurodegeneration. Here, we report cryoelectron microscopy (cryo-EM) structures of MCT8 and OATP1C1 bound with the active thyroid hormone triiodothyronine (T3) and the prohormone thyroxine (T4) at 2.9 and 2.3 Å resolutions, respectively. Combined …

Spartan Daily, October 2, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 18

Functional Effects Of Heavy Metal Exposures On N6-Methyladenosine (M6a) Methylation And Other Epitranscriptomic Modifications In The Central Nervous System, Niraj Lodhi, Lauren Powell, Jay S. Schneider

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Among different RNA methylations, N6-methyladenosine (m6A) is the most abundant in the brain and determines the fate of RNA through reversible processes using methyltransferases, demethylases, and methyl-binding proteins. The reversibility of m6A is an emerging regulatory mechanism for gene expression, regulating many aspects of RNA metabolism and influencing learning and memory processes. Global m6A profiles are dynamically modified via the activity of various writers, readers, and erasers. However, m6A alterations from exposure to heavy metals, including the metals lead (Pb), cadmium (Cd), cobalt (Co), and manganese (Mn) and the metalloid arsenic (As), and the impact on brain function, are not …

Engagement With And Impact Of An Mhealth App For Childhood Obesity Prevention And Management: Protocol For A Mixed Methods Study, Madison Milne-Ives, Ananya Ananthakrishnan, Sophie R. Homer, Jackie Andrade, Edward Meinert

School of Psychology

Background: Childhood obesity is a serious global health concern that affects approximately 20% of children worldwide. Digital health behavior change interventions have the potential to improve behaviors that can contribute to childhood obesity, such as diet and physical activity, but often lack sufficient user engagement to achieve significant impact. Objective: The aim of this project is to develop evidence to better understand how users engage with digital interventions and how behavior change techniques can be leveraged to support engagement. Specifically, the study will examine the impact of a family-focused app for childhood obesity prevention on health behaviors, health outcomes, and …

The Impact Of Off-Site Manufacturing Technology On The Project Management Triangle In The Saudi Housing Sector, Saad S. Almady, Ahmed M. Alhazmi, Essam S. Almahmoud

Mansoura Engineering Journal

This study examines the impact of Off-Site Manufacturing (OSM) and construction sites on housing projects in the Kingdom of Saudi Arabia. The study aims to strike a balance between achieving the highest quality, lowest cost, and expedited construction of housing units. OSM technology involves the production of construction components outside the site, followed by their transportation and installation on the final site. The study seeks to assess the contribution of OSM’s utilization in enhancing project performance, measured against the project management triangle (quality, cost, and time), and compare it with the traditional construction method. To achieve this objective, a residential …

The World Of Balenciaga: Reconstructing The Spanish Contribution To The 1974 Exhibition [Ponencia] Ii Congreso Internacional Sobre Cristóbal Balenciaga, Daniele Gennaioli, Tomasso Mozzati

Congresos y Conferencias

This publication contains the abstracts of the papers which will be presented at the Second International Cristóbal Balenciaga Conference, to take place at the Cristobal Balenciaga Museum (Getaria) on 2 and 3 October 2025. These papers represent a selection of 24 proposals, from among the 63 received, made by a Scientific Committee of recognized experts in the field according to the double blind method. The objective was to guarantee the presentation of rigorous, quality papers and to place the study of Cristóbal Balenciaga in the field of academic research. Given the importance of Balenciaga, the selected proposals come not only …

Factors Influencing Employee Green Behavior And Employee Green Attitude Among Muslims In Indonesia, Kurnia Sari Kasmiarno, Mahjus Ekananda, Gina Destrianti Karmanto

Journal of Environmental Science and Sustainable Development

In a Muslim majority, developing country like Indonesia, religion shapes employees’ work ethic and professional behavior, embedding spiritual and cultural values into the workplace. Despite the increasing attention to pro-environmental behavior, previous studies have largely examined Green Human Resource Management (GHRM), religiosity, and environmental concern separately, often focusing on a single sector. This leaves employees from various occupational backgrounds underexplored. This study aims to examine the effects of Green Concern (GC), Green Motivation (M), GHRM, and Religiosity (REL) on Employee Green Behavior (EGB) and Employee Green Attitude (EGA) of Muslim employees in Indonesia. Data were collected through a quantitative survey …

Towards The Four-Hour Rule: Impact Of Observation Units And Emergency Medicine Specialists In An Indonesian Tertiary Hospital, Septo Sulistio, Ascobat Gani

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Emergency Department (ED) overcrowding is a global challenge. In response, the government of Indonesia mandates an ED Length of Stay (LOS) of ≤4 hours. This study aims to evaluate the impact of implementing an Emergency Department Observation Unit (EDOU) combined with an Emergency Medicine (EM) specialist-led disposition process on ED LOS at a national referral hospital in Indonesia. This was a retrospective, pre-post analysis comparing all ED visits in 2023 (pre-intervention, n = 26,282) with all visits in 2024 (post-intervention, n = 31,483). The primary outcome was the proportion of patients with an ED LOS ≤4 hours. Secondary outcomes included …

Kenyon Collegian - October 2, 2025

The Kenyon Collegian

No abstract provided.

Revisiting The Spin–Lattice Relaxation Of Homonuclear In-Phase And Antiphase Nmr Magnetization, Lauren M. Kehoe, Zachary G. Mayes, Kelsey E. Brakensiek, Emma L. Ellis, Adam J. Alderfer, Lingyu Chi, Klaus Woelk

Chemistry Faculty Research & Creative Works

Hyperpolarization techniques such as dynamic nuclear polarization (DNP), chemically induced dynamic nuclear polarization (CIDNP), and parahydrogen-induced polarization (PHIP) enhance the sensitivity of NMR spectroscopy and MRI, but the associated antiphase magnetization patterns often relax faster than those of conventional in-phase signals. This study analyzes the spin–lattice relaxation matrix for single-quantum transitions in an isolated, weakly coupled two-spin AX system to identify eigenvectors and eigenvalues that govern the time evolution of in-phase and antiphase longitudinal magnetization. The analysis predicts that AX antiphase magnetization, such as that generated by PHIP hydrogenations in high magnetic field, can relax up to twice as fast …

Implications Of Electric Vehicles Use On Value Co-Creation And Improving Community Welfare, Rastinia Kamila Hanum, Rizal Edy Halim

Journal of Environmental Science and Sustainable Development

Transportation is closely related and to support daily community mobility, 90% of road transportation operates on fossil fuel and it has always been accompanied by new innovations. Electric vehicles are predicted to be the future transportation to reduce greenhouse emissions. This study combines theories on behavioral and technology acceptance to create value co-creation and enhance community well-being. This quantitative study surveyed 210 respondents from the target community especially in Java island, who intend to adopt electric vehicles (EVs) using Google Form. PLS-SEM was used to evaluate research framework which integrates TPB, Technology Acceptance Model (TAM), and Unified Theory of Acceptance …

Green Human Resource Management, Employee Behavior, And Organizational Innovation: A Multi-Theoretic Pathway To Sustainable Competitiveness, Iwan Perwira, Hernita Hernita, Suardi Suardi, Andi Tenry Sose, Muhammad Azizurrohman

Journal of Environmental Science and Sustainable Development

As sustainability imperatives reshape global tourism, this study investigates how Green Human Resource Management (GHRM) practices can serve as strategic levers for driving sustainability performance and competitive advantage within Indonesia’s tourism sector. Amid rising environmental expectations and regulatory mandates, the research integrates Social Learning Theory, the Resource-Based View, and Institutional Theory to construct and test a model that links top management support, green organizational culture, and regulatory pressure to GHRM adoption. Using a cross-sectional survey of 510 employees and managers across eco-certified tourism firms in five Indonesian destinations, the study employed Partial Least Squares Structural Equation Modeling (PLS-SEM) to analyze …

A Multidecadal Analysis Of Groundwater Level And Streamflow Decline In Southern Forest Catchments, Western Australia, Richard J. George, Rose-Anne Bell, W. Lachlan Mccaw, Gregory Paul Raper

Natural Resources Research Articles

Previous analysis of hydrological data in the eucalypt dominated forests of Western Australia’s Darling Ranges show that reduced winter rainfall over the last 50 years has lowered groundwater levels and diminished streamflow by up to 70%. Consequently, climate-independent reverse osmosis seawater desalination and groundwater resources now supply Perth and nearby regional areas, as runoff from forested catchments is no longer sufficient or reliable. In the high rainfall (~1200 mm/yr) mixed forest areas dominated by Eucalyptus diversicolor (karri) and Eucalyptus marginata (jarrah) 200 km to the south of Perth (the ‘Southern Forest’), similar analysis of climate impacts on watertables has not …

October 2, 2025, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

A Mast Cell Receptor Mediates Post-Stroke Brain Inflammation Via A Dural-Brain Axis, Ruchita Kothari, Mostafa W Abdulrahim, Hyun Jong Oh, Daniel H Capuzzi, Collin B Kilgore, Yaowu Zhang, Sarbjit S Saini, Jennifer E Kim, Justin M Caplan, Fernanado L Gonzalez, Christopher M Jackson, Chetan Bettegowda, Judy Huang, Bhanu P Ganesh, Chunfeng Tan, Raymond C Koehler, Rafael J Tamargo, Louise D Mccullough, Risheng Xu, Xinzhong Dong

Faculty, Staff and Student Publications

The immune environment surrounding the brain plays a fundamental role in monitoring signs of injury. Insults, including ischemic stroke, can disrupt this balance and incite an exaggerated inflammatory response, yet the underlying mechanism remains unclear. Here, we show that the mast-cell-specific receptor Mrgprb2 regulates post-stroke brain inflammation from the meninges. Mrgprb2 causes meningeal mast cell degranulation after stroke, releasing immune mediators. This process recruits skull bone marrow neutrophils into the dura and further promotes neutrophil migration from the dura into the brain by cleaving the chemorepellent semaphorin 3a. We demonstrate that the human ortholog, MRGPRX2, is expressed in human meningeal …

A Needed Nomenclature For Nucleosomes, Michael-Christopher Keogh, Genevieve Almouzni, Andrew J Andrews, Karim-Jean Armache, Cheryl H Arrowsmith, Mark T Bedford, Jacques Côté, Yael David, John M Denu, Beat Fierz, Benjamin A Garcia, Karen C Glass, Or Gozani, Kristian Helin, Steven Henikoff, Ole N Jensen, Steven Z Josefowicz, Neil L Kelleher, Tatiana G Kutateladze, Herbert H Lindner, Chao Lu, Karolin Luger, Parag Mallick, Catherine A Musselman, Tom W Muir, Ljiljana Paša-Tolić, Robert Schneider, Xiaobing Shi, Yang Shi, Simone Sidoli, Lloyd M Smith, Jessica K Tyler, Cynthia Wolberger, Jerry L Workman, Brian D Strahl, Nicolas L Young

Faculty, Staff and Student Publications

Histone post-translational modifications (PTMs) are crucial to eukaryotic genome regulation, with a range of reported functions and mechanisms of action. Though often studied individually, it has long been recognized that the modifications function by combinatorial synergy or antagonism. Interplay may involve PTMs on the same histone, within the same nucleosome (containing a histone octamer), or between nucleosomes in higher-order chromatin. Given this, the field must distinguish ever greater complexity, and the context in which it is studied, with brevity and precision. The proteoform was introduced to define individual forms of a protein by sequence and PTMs, followed by the nucleoform …

Long-Term Outcomes In Flt3-Mutated Acute Myeloid Leukemia After Frontline Hypomethylating Agent, Venetoclax And A Flt3 Inhibitor, Nicholas J Short, Sanam Loghavi, Musa Yilmaz, Omer Karrar, Kunhwa Kim, Tapan M Kadia, Gautam Borthakur, Ghayas C Issa, Joseph Jabbour, Betul Oran, Elizabeth J Shpall, Uday Popat, Keyur P Patel, Mark Routbort, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian, Naval Daver

Faculty, Staff and Student Publications

Triplet regimens with a hypomethylating agent, venetoclax and a FLT3 inhibitor yield high rates of response in newly diagnosed FLT3-mutated AML. However, the long-term outcomes and patterns of relapse with these triplet regimens are not well-established. In this retrospective analysis, 73 patients with newly diagnosed FLT3-mutated AML received a frontline FLT3 inhibitor-containing triplet regimen. The composite complete remission (CR) and CR with incomplete hematologic recovery (CRi) rate was 93%. Next-generation sequencing FLT3-ITD MRD negativity (sensitivity: 0.005%) was achieved in 60% of patients after cycle 2 and 90% after cycle 4. The estimated 3-year relapse-free survival (RFS) for FLT3-ITD-mutated and FLT3 …

Rare Variants In Prkci Cause Van Der Woude Syndrome And Other Features Of Peridermopathy, Kelsey Robinson, Sunil K Singh, Rachel B Walkup, Dorelle V Fawwal, Kendra M Vilfort, Amanda Koloskee, Azeez Fashina, Wasiu Lanre Adeyemo, Terri H Beaty, Azeez Butali, Carmen J Buxó, Wendy K Chung, David J Cutler, Michael P Epstein, Brooklynn Gasser, Lord J J Gowans, Jacqueline T Hecht, Anuj Mankad, Lina Moreno Uribe, Daryl A Scott, Gary M Shaw, Mary Ann Thomas, Seth M Weinberg, Eric C Liao, Harrison Brand, Mary L Marazita, Robert J Lipinski, Jeffrey C Murray, Robert A Cornell, Elizabeth J Leslie-Clarkson

Faculty, Staff and Student Publications

Van der Woude syndrome (VWS) is an autosomal dominant disorder characterized by lower lip pits and orofacial clefts (OFCs). With a prevalence of ∼1 in 35,000 live births, it is the most common form of syndromic clefting. Most VWS is attributed to variants in IRF6 (∼70%) or GRHL3 (∼5%), leaving up to 25% of individuals without a molecular diagnosis. Both IRF6 and GRHL3 function in a transcriptional regulatory network (TRN) governing differentiation of periderm, a single epithelial cell layer preventing pathological adhesions during palatogenesis. Periderm disruption can elicit a spectrum of phenotypes, including lip pits and OFCs, pterygia, and severe …

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Louisiana Law Review

No abstract provided.

I Knew You Were Trouble: Deepfakes, Misinformation, And The Threat To Elections, Rachael Youngblood

Louisiana Law Review

No abstract provided.

Frozen Mindset: Relationship Beliefs In Blutch’S Peplum, Mckenna Holz

International Journal of Undergraduate Research and Creative Activities

Blutch’s fictional, peplum style bande dessinée titled Peplum explores the consequences of a relationship influenced by hegemonic masculinity and a desire for the penetrator role. His protagonist Publius experiences three failed relationships because of the delusion of a destiny relationship belief. Publius’ relationship odyssey enlightens him to adopt a growth relationship belief which pushes Blutch’s message of healthy relationship dynamics. Blutch focuses on Publius’ eyes to show this belief transition and uses bande dessinée techniques of rhythm, shading, and mise en page to achieve this visual.

Educating Future Nurse Practitioners And Physician Associates On Pretreatment Of Swallowing In Head And Neck Cancer, Hannah M. Berk, Erin L. O'Bryan, Imran Musaji, Carly A. Thomas, Jamie Harrington

Teaching and Learning in Communication Sciences & Disorders

Head and neck cancer treatment frequently results in long-term severe swallowing deficits, often requiring feeding tube dependency. Patients who have completed swallowing exercise programs before and during cancer treatment experienced more positive swallowing outcomes, but most patients are not referred for swallowing intervention early enough in their care to prevent long-term deficits. This student research project aimed to measure health profession students’ knowledge of swallowing pretreatment for head and neck cancer patients and to investigate the impact of an educational module developed and presented by a Communication Sciences and Disorders graduate student to improve knowledge and awareness of this clinical …

The Role Of Interprofessional Education In Preparing The Next Generation Of Pre-Service Professionals: A Pilot Study, Shannon Wade Salley, Jennifer Cuchna, Tammy M. Hines, Karla Collins, Jennifer Hutchinson

Teaching and Learning in Communication Sciences & Disorders

Interprofessional practice is a growing expectation in health and human services professions, as is collaboration between education professionals, to bring the best care and services to clients and students. Future professionals need to learn about other professions and be taught how to work with others as members of an interprofessional team. This mixed-methods pilot study examined the impact of an interprofessional education experience on future education, health, and human services professionals, including speech language pathologists, teachers, and counselors. Event participants showed an increased understanding of the roles of other professionals and recognition of the benefits of working in an interprofessional …

The Impact Of Year-Long Teaching Symposium On Faculty Implementation Of Evidence-Based Education Approaches, Julie A. Honaker, Joan Besing, Radhika Aravamudhan, Loretta Nunez

Teaching and Learning in Communication Sciences & Disorders

On May 17-28, 2021, the American Speech-Language-Hearing Association (ASHA) launched a two-week teaching symposium on Foundational Communication Sciences and Disorders (CSD) science courses and innovation in teaching and learning: speech, language, and hearing sciences. Participants also joined asynchronous threaded discussions and a series of synchronous peer-based online discussions. Ninety-four participants completed a teaching symposium pre-assessment and two post-assessment surveys, and quantitative and qualitative results were reviewed across all time points. All 94 participants indicated motivation to use evidence-based strategies to improve teaching and students’ learning after participation, reinforcing the need for continued review and faculty engagement in these topics.

Exploring Metacognition And Mindset In Communication Sciences And Disorders Graduate Students, Kelly Rutherford

Teaching and Learning in Communication Sciences & Disorders

Purpose: Embedding metacognition into higher education curricula can be particularly challenging in accredited communication sciences and disorders (CSD) graduate programs. Many faculty aim to promote both metacognitive development and a growth mindset among students. This pilot study explored the use of periodic "mindset check-in" surveys within a neurology course for speech-language pathology (SLP) students to examine changes in student attitudes and learning behaviors over time.

Method: This study examined metacognition and mindset in graduate CSD students through six surveys tracking attitudes, study habits, and mindset. Using varied question formats, data analysis summarized patterns and cohort growth over time.

Results: Students …