Digital Commons Network^™

The Role Of Fibroblast Activation Protein On Left Ventricular Growth And Extracellular Matrix Remodeling As A Function Of Age And Pressure Overload, Amelia Marie Churillo

Theses and Dissertations

Fibroblast activation protein (FAP) is abundantly expressed in cancer associated fibroblasts and contributes to extracellular matrix (ECM) remodeling. Recent studies using imaging techniques have identified increased levels of FAP in the left ventricle (LV) of patients identified as at risk for developing heart failure. However, the role of FAP in regulated LV myocardial structure and function remains unclear. This project tested two hypotheses: First, genetic ablation of FAP would modify LV structure and function and be more pronounced with aging. Second, genetic ablation of FAP would modify LV structure and function with LV pressure overload (LVPO) accompanied by ECM remodeling.

Memories Of Trees Past: Coexistence Implications Of Legacy Conspecific Density Dependence, Lukas J. Magee, Daniel J.B. Smith, David Bauman, Po-Ju Ke, Helene C. Muller-Laudau, Kristina J. Anderson-Teixeira, Jessica Shue, David A. Orwig, Sean M. Mcmahon, Stephanie Bohlman, Raelene M. Crandall, Ben Weinstein, Sergio Marconi, Jeremy W. Lichstein, James F. Gillooly, Robert Bagchi, Joseph A. Lamanna, Daniel J. Johnson

Biological Sciences Faculty Research and Publications

The Janzen-Connell Hypothesis posits that plant species diversity is maintained by a reduction in seedling survival near living conspecific trees relative to heterospecifics–known as negative conspecific density dependence (CDD). CDD facilitates coexistence if stronger than heterospecific density dependence (HDD). However, whether and how long CDD persists after trees die is unknown. In a three-year study across three forests, we monitored seedling survival near living and dead trees, both conspecific and heterospecific, across a seven-year chrono-sequence since tree death. CDD persisted for at least 5 years after tree death (‘legacy CDD’), and most species showed stronger CDD relative to HDD through …

Dynamic Rewiring Of Microrna Networks In The Brainstem Autonomic Control Circuits During Hypertension Development In The Female Spontaneously Hypertensive Rat, Alison Moss, Ankita Srivastava, Lakshmi Kuttippurathu, James S. Schwaber, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

We describe global microRNA (miRNA) changes in the central autonomic control circuits during the development of neurogenic hypertension. Using the female spontaneously hypertensive rat (SHR) and the normotensive Wistar Kyoto (WKY), we analyzed the dynamic miRNA expression changes in three brainstem regions-the nucleus of the solitary tract, caudal ventrolateral medulla, and rostral ventrolateral medulla-as a time series beginning at 8 wk of age before hypertension onset through to extended chronic hypertension. Our analysis yielded nine miRNAs that were significantly differentially regulated in all three regions between SHR and WKY over time. We collated computationally predicted gene targets of these nine …

Combating Obesity: Creating A Comprehensive Wellness Plan For Uninsured & Low-Income Populations, Kayla C. Berrios

Doctor of Nursing Practice Scholarly Projects

Aim: The aim of this project was to research the specific barriers encountered by obese patients that are low-income and uninsured. The goal of this data collection was to inform the stakeholders involved in creating a comprehensive wellness plan for obese patients.

Background: The staff at Good Neighbor Clinic have struggled to support their support their obese patients with weight reduction. Many of the ailments that patients seek care for correlate to their obesity. Health promotion in this community clinic needs a more comprehensive program to support patients during their weight loss experience, providing support and resources to allow for …

Richmond Law Magazine: Autumn 2025

Richmond Law Magazine

Danielle Stokes and the energy discussion

Beyond the page

The mentorship web

Institute For Global Health And Development : Issue 12 - October 2025, Institute For Global Health And Development

IGHD Newsletters

• Dr. Bhutta Awarded the Virchow Prize 2025 For Global Health
• Mapping Climate Vulnerability and Resilience Across the Prepare Pakistan Project – Promoting Climate Resilience, Pakistan’s High-Risk Districts
• Choice Project Dissemination Workshop Held in Accelerating Progress Towards Health and Health-Related SDGS Nairobi
• Farhana Tabassum Attends the Inauguration Of “Imagining Life” At the Climate Action Center, Karachi
• IGHD Participates in the Green Zameen Fellowship on Sustainable Energy Transition
• IGHD Team Leads Systematic Reviews & Meta-Analysis
• Empowering Research in Maternal Health Dr. Khadija Vadsaria Completes Her PhD at Aga Khan University
• Climate Change and Maternal Health Dr. Jai Das Featured in the Economist …

Check Out The Library, 2025 Fall Issue, Cal Poly Humboldt Library

Library Publications

Issue 20

A Modified Fama-Macbeth Model Based On The Single-Index Model, Mariam Jumaah Mousa, Munaf Yousif Hmood

Journal of Economics and Administrative Sciences

The aim of this essay is to use a single-index model in developing and adjusting Fama-MacBeth.  Penalized smoothing spline regression technique (SIMPLS) foresaw this adjustment.  Two generalized cross-validation techniques, Generalized Cross Validation Grid (GGCV) and Generalized Cross Validation Fast (FGCV), anticipated the regular value of smoothing covered under this technique. Due to the two-steps nature of the Fama-MacBeth model, this estimation generated four estimates: SIMPLS(FGCV) - SIMPLS(FGCV), SIMPLS(FGCV) - SIM PLS(GGCV), SIMPLS(GGCV) - SIMPLS(FGCV), SIM PLS(GGCV) - SIM PLS(GGCV). Three-factor Fama-French model—market risk premium, size factor, value factor, and their implication for excess stock returns and portfolio returns—were estimated on …

Unleashing The Research Superpowers Of Ap Students, Lindsey Douglas, Suzanne Rook Schilf, Camille Cooper, Jennifer Groff

Presentations

No abstract provided.

Civil Appeals Mediation Program 2024 Mediation Colloquy: 50 Years Of Building Bridges Through Appellate Mediation

Cardozo Journal of Conflict Resolution

On December 17, 2024, the Second Circuit Court of Appeals and its CAMP program hosted Justice Sotomayor to celebrate the 50th Anniversary of the establishment of CAMP. During the Colloquy, the 50th Anniversary CAMP documentary video was premiered.

Accuracy Of Femoral Head Center Reconstruction Using A Straight Cementless Rectangular Stem: An In-Silico Study Comparing Elderly And Middle-Aged Patients, Hidde D Veldman, Ide C Heyligers, Philip C Noble, Tim A E J Boymans

Faculty, Staff and Student Publications

Introduction: Accurate reconstruction of the femoral head center (FHC) is essential for restoring hip biomechanics in total hip arthroplasty (THA). Previously described age-related morphological changes-such as canal widening and a mediocaudal FHC shift-may complicate anatomical reconstruction in all age-categories using a single non-modular cementless stem. This study assessed the capacity of such implant to achieve adequate FHC reconstruction across age groups and sexes.

Methods: Virtual implantation of a non-modular cementless stem (SL-PLUS™) was performed in CT-based 3D reconstructions of 148 femora from middle-aged (< 80 years) and very elderly (≥80 years) subjects. For each case, the optimal implant size, type (standard or lateral), and modular head (-4 mm, 0 mm or +4 mm) were selected. FHC deviation was measured in three dimensions; reconstructions were considered adequate if < 5 mm in all directions.

Results: Overall, 92.4 % of reconstructions were considered adequate. No significant differences in reconstruction accuracy could …

Sinclair Lewis Society Newsletter, Vol 34, No. 1, The Sinclair Lewis Society

Sinclair Lewis Society Newsletter

“Every Time Something Big and Stupid Happens in America, Lewis Becomes Popular Again”: A Conference Retrospective, with Notes from a First-Time Visitor to Sauk Centre by Shaun F. Richards

Pickerbaugh’s Rhymes: Another Target of Satire in Arrowsmith by George Killough

In Memoriam: Robert E. Fleming, Father of the Sinclair Lewis Society by Sally E. Parry

Arrowsmith 100 years later: Osterholm Links Lewis’s Novel to Modern Society by Shalon Wilber

Becoming A Writer: A Review of Writers Like Us: My Life with Sinclair Lewis, by Barnaby Conrad, with Barnaby Conrad III by Shaun F. Richards

Sinclair Lewis and the Pulitzer …

Signs & Symbols, Fall 2025, Illinois State University, Department Of Sociology And Anthropology

Signs & Symbols

Newsletter of the Illinois State University Department of Sociology and Anthropology. An email newsletter version of this document is available at https://web.archive.org/web/20260223203547/https://news.illinoisstate.edu/newsletters/signs-symbols-fall-25/.

Bipolar Spinal Correction Reduces Transfusion Rate And Hospital Stay Compared With Traditional Posterior Spinal Fusion In Children With Scoliosis Secondary To Cerebral Palsy, Kristopher Lundine, Matthias Lu, Timothy C Borden, Samuel Yoon, Mia Percival, Michael B Johnson

Faculty, Staff and Student Publications

Purpose: Patients with neuromuscular scoliosis due to Cerebral Palsy (CP) are complex due to their curve severity and associated medical comorbidities. Spinal fusion is associated with high risk of peri-operative complications and large blood loss requiring allogenic red blood cell (RBC) transfusion. In June 2017, our tertiary paediatric institution implemented a new minimally-invasive approach for the treatment of neuromuscular scoliosis, Bipolar Spinal Correction (Bipolar), a technique first published by Miladi et al. in 2018. This study represents an analysis of the initial experience of this technique to see if it achieves the goal of minimally invasive surgery by decreasing surgical …

Irf6 Regulates Adherens Junction Proteins And Inflammatory Cytokines In Salivary Acinar Cells And Its Expression Is Elevated In Sjӧgren’S Syndrome, Vi Pham, Antonio Hernandes Chaves Neto, Julia Zheng, Mary Elmeniawi, Krishna Kumar Kookal, Muhammad F Walji, Mary C Farach-Carson, Walid D Fakhouri

Faculty, Staff and Student Publications

Objective: To investigate the mechanism of Interferon Regulatory Factor 6 (IRF6) function in regulating adherens junction proteins and inflammatory cytokines in human salivary acinar cells and Sjögren's syndrome biopsies.

Design: We used mouse model, salivary cell lines, and human salivary gland (SG) biopsies to investigate IRF6 function in SG cellular integrity and immunomodulation.

Results: In Irf6-null mice, we observed myoepithelial cell detachment from acinar cells of major SGs, and the acini were remarkably disorganized compared to wild-type littermates. At the molecular level, the acinar differentiation markers E-cadherin and MIST1 were markedly reduced in Irf6-null embryonic SG, while the proinflammatory cytokines, …

A Comparison Of Return To Sport After Bankart Repair Versus Latarjet For Shoulder Instability: A Systematic Review, Claire E Noyes, Grace E Johnston, Nicholas Vaver, Patrick M Garvin, Jonathan T Bravman, James W Genuario, Braden K Mayer, Thomas J Noonan, Carson Keeter, Eric C Mccarty

Faculty, Staff and Student Publications

Background: Glenohumeral instability can be addressed surgically with repair of the capsulolabral complex, the "Bankart" repair, or bone augmentation with coracoid autograft, the "Latarjet" procedure. Superior return-to-sport (RTS) rates with either Bankart repair or Latarjet have yet to be delineated, and it remains unclear which surgical procedure is optimal.

Purpose: To review the current literature and report on RTS data for patients who received Bankart repair or Latarjet to address glenohumeral instability.

Study design: Systematic review; Level of evidence, 4.

Methods: This systematic review and meta-analysis was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines …

Feasibility And Usage Of A Virtual Assistant Device In Cognitively Impaired Homebound Older Adults, Matthew Nunez, Prisha Patel, Lindsey Ulin, Leslie Kian, Martin Cominsky, Jason Burnett, Jessica L Lee

Faculty, Staff and Student Publications

Social technology in older adults can improve self-rated health; however, there can also be difficulties using it. Our study aimed to evaluate the feasibility and acceptance of virtual assistant device (VAD) use in cognitively impaired homebound older adults. 52 newly referred Meals on Wheels clients aged 60 and older were recruited for a three-phase study: 6 weeks of meals alone (control), followed by 6 weeks of meals+Alexa Echo Show 8 (AES8) basic usage, and lastly 6 weeks of meals+AES8 advanced usage. Technology acceptance with the AES8 was significantly higher by the end of the study and participants anecdotally enjoyed playing …

Dissociation Of Subjective And Objective Measures Of Trust In Vehicle Automation: A Driving Simulator Study, Samuel Petkac, Tetsuya Sato, Kun Xie, Yusuke Yamani

Psychology Faculty Publications

Trust is a crucial factor that influences human-automation interaction in surface transportation. Previous research indicates that participants tend to display higher levels of subjective trust toward lower-level automated systems compared to high-level automated systems. However, administering subjective trust measures via questionnaires can interfere with primary task performance, limiting researchers' ability to measure trust continuously in a real-world manner. In the current driving simulator study, 25 drivers using an advanced driving system (ADS) were randomly assigned to either an active (L2) or passive (L3) automated driving condition. Participants experienced eight near-miss driving scenarios with or without obstructions in a distributed driving …

University Of San Diego Magazine Fall 2025, Publications Department

University of San Diego Magazine (1992- )

Beauty, Goodness and Truth; Dear Toreros; Around Alcalá Park; At The Edge of It All; Faith In Action; Torero Spotlight; Torero Athletics; Toreros Making Waves; In Memoriam; Leading With Love

The Access Assembly: Learning Together, Building Friendships, And Strengthening Our Leadership Capacities, Chandra Turpen, Brianne Gutmann, Robert P. Dalka, Gina M. Quan, Mackenzie Carlson, Joel C. Corbo, Gabrielle Jones-Hall, Megan Marshall Smith, Devyn E. Shafer

Faculty Research, Scholarly, and Creative Activity

Founded in 2014, the Access Network brings together nine student-centered, university-based programs that pursue systemic change towards a vision of a more diverse, equitable, inclusive, and accessible STEM community. Leaders at the Network-level and program-level are either current students (undergraduate or graduate) or young faculty and professional scientists, many of whom started out as student leaders in Access programs. Over the last 9 years, Access has brought people together (virtually or in-person) for an annual event called the "Assembly." Student leaders who attend the Assembly appreciate community-building and networking opportunities that help them build capacity for leading local site programming. …

2025 October, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for October of 2025.

The Role Of Artificial Intelligence In Data-Driven Marketing: Enhancing Marketing Efficiency, Customer Engagement, And Business Performance In Smes, Abdelrehim Awad

Journal of Economics and Administrative Sciences

Marketing applications of Artificial Intelligence (AI) have revolutionized business strategy providing Small and Medium-Sized Enterprises (SMEs) with superior customer engagement tools, strategic segmentation, and performance improvement. This study investigates the impact of marketing practices that are AI-based, like customer segmentation, predictive analytics, and marketing automation, on marketing efficacy, customer engagement, and on overall business performance in Egyptian small and SMEs. Utilizing a mixed-methods design, which means the integration of both quantitative (survey) and qualitative (interview) data analyzed with various methodological paradigms. The study consisted of structured surveys to 100 marketing professionals across several Egyptian SMEs and 30 executive interviews. Quantitative …

Southeast Asia Higher Education Changes And Emerging Futures, Muhammad Hali Aprimadya, Lily Kong, Angel Calderon, Hamish Coates

Research Collection School of Social Sciences

This paper unpacks recent developments and future directions in Southeast Asian higher education. It takes stock of higher education systems in three selected countries, Australia, Indonesia and Singapore. It sketches these systems, distils several changes around 2024, and discusses emerging directions for education, research and universities. The paper concludes by looking at what is required to catalyse transformations likely to impel future progress.

Everyday Norms Have Become More Permissive Over Time And Vary Across Cultures, K. Eriksson, P. Strimling, I. Vartanova, Andree Hartanto

Research Collection School of Social Sciences

Every social situation that people encounter in their daily lives comes with a set of unwritten rules about what behavior is considered appropriate or inappropriate. These everyday norms can vary across societies: some societies may have more permissive norms in general or for certain behaviors, or for certain behaviors in specific situations. In a preregistered survey of 25,422 participants across 90 societies, we map societal differences in 150 everyday norms and show that they can be explained by how societies prioritize individualizing moral foundations such as care and liberty versus binding moral foundations such as purity. Specifically, societies with more …

Law As A Tool Of Empire: A Transhistorical Comparison Of Mandate Palestine And Ancient Rome, Will L. Hisle

Armstrong Undergraduate Journal of History

Through a comparative analysis of Law and Identity in Mandate Palestine by Assaf Likhovski, and A Legal History of Rome by George Mousourakis, this essay demonstrates that law was crucial to the expansion of empire. When read in tandem, these monographs provide a transhistorical framework for viewing law outside of itself, as a mechanism of colonial and imperial domination.

Decoding Influence: Cosmetic Industry Strategies, Media Beauty Standards, And Their Mental Health Impact On Generation Z Consumers, Tatiana Avila Velasquez

Undergraduate Theses and Capstone Projects

This research explores the complex relationship between cosmetic industry marketing strategies, media-driven beauty standards, and the mental health of Generation Z consumers. Utilizing both qualitative and quantitative methods, the study examines how frequent exposure to curated beauty ideals and persuasive advertising shapes self-esteem, confidence, and personal identity among young adults. Through surveys and in-depth interviews, the research highlights the evolving nature of cosmetic use, revealing how early engagement with beauty products often stems from social conditioning and personal insecurities. Participants describe a shift from using cosmetics as a means of concealment to embracing them for creative expression and self-care. However, …

Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf

Arts & Sciences Faculty Publications

Nonmajors (i.e., undergraduate students not majoring in the natural sciences) constitute a majority of United States college graduates and are a large potential audience for courses with ecology content. However, nonmajors may be unmotivated to learn about ecology because they perceive it to be uninteresting and irrelevant to their everyday lives or career goals. Although the Four-Dimensional Ecology Education (4DEE) framework can be adapted for nonmajors courses as a starting point to improve student engagement, we suggest that nonmajors ecology instructors also use ecology hooks as effective gateways to 4DEE that will motivate and deepen student learning. Selecting and developing …

Intelligence As An Instrument Of National Power: Lessons Learned From The Tensions Between Serbia And Kosovo, Vadym Chernysh

Journal of Strategic Security

Intelligence activity is unique; it can be a valuable and powerful tool in the hands of state leaders. Leaders should rely not solely on their perception or intuition to leverage the intelligence instrument of national power but rather on understanding this phenomenon and its inherent qualities. Often, political leadership may confuse the functions of intelligence and law-enforcement agencies, leading to the ineffective or inefficient use of national power instruments to achieve strategic goals. Leveraging the intelligence instrument of national power in prolonged conflicts with a larger adversary is a crucial aspect of statecraft. The role of intelligence can be vital …

Vulnerable State’S Foreign Policy Navigation In A Multipolar World: Discerning Ethiopia’S Security Engagement With Turkey, Henok Getachew

Journal of Strategic Security

Throughout its modern history, the Ethiopian state has operated in space that constraints its strategic autonomy. Since the mid of the twenty-first century, the Ethiopian state has consistently struggled to survive in the face of formidable challenges that manifested in the forms of irredentism, aggression, civil war, and external pressure. To deal with such security conundrums, maintaining strategic partnership for instance is not a new phenomenon in the tradition of Ethiopia’s foreign policy. Over the years, it has employed inter alia alliance, loose partnership, and asymmetric relationships with other states as well as collective security to ameliorate security risks originating …

The I2u2: China’S Increasing Role In The Middle East And Geostrategic Implications On India, Pooja Devi, Jyoti Singh Ph.D.

Journal of Strategic Security

In the present era, the concept of minilateralism has emerged as an essential instrument of the attainment of a country’s strategic interests. Consequently, the global world is shifting from multilateral alliances to minilateral groupings. The article analyzes the emergence of a minilateral construct and the formation of minilateral platform I2U2. The newly established quadrilateral group I2U2, which includes India, Israel, the UAE and the United States, is called ‘the Middle East Quad.’ The economic partnership is aimed at utilizing the different sector capacities of member countries to counter shared challenges that have occurred in the past few years. Six key …