Digital Commons Network^™

Midweek Memo, Georgia Southern University

Midweek Memo

• Applaud
• Remember
• Share
• Experience
• Around the Nest

Insights Into Spheroid Formation: Interaction Of Ovarian Cancer Cells With Macrophage Populations In The Tumor Microenvironment, Jing Xiao, Deyarina Gonzalez, Robert Steven Conlan, Bruna Corradetti

Faculty, Staff and Students Publications

Background: Treating advanced ovarian cancer (OC) is challenging due to the immunosuppressive tumor microenvironment. This study investigates tumor-immune cell interactions using organotypic spheroid models that simulate the in vivo microenvironment.

Methods: A dual-model spheroid system was established combining serous adenocarcinoma SKOV-3 cells with monocytes, pro-inflammatory (MΦ1) or anti-inflammatory (MΦ2) macrophages, or their derived exosomes (EXOs). In Model A, immune cells or EXOs were co-seeded with tumor cells to replicate early heterotypic aggregation. In Model B, immune cells or EXOs were introduced 24 h post-spheroid formation to simulate immune infiltration into established spheroids. Spheroid morphology was quantified by diameter and circularity, …

The Influence Of Gender-Based Violence On Women’S Career Development: Perspectives From Higher Education Career Guidance Practitioners In Ireland, Lianne Rooney

Research Outputs: 2025-Present

Women and girls are disproportionately subjected to GBV and the effects for victim-survivors are multiple and long-lasting. An under-considered dimension is the profound influence GBV has on the careers of the women who experience it.This qualitative study aimed to explore this issue from the perspective of career practitioners. The research set out to understand how career practitioners working in Irish Higher Education institutions understand GBV, how they identify this in a career context and the professional competencies they require to support female clients who may be affected by it.

Does Cognitive Frame Affect Clinical Reasoning Among Medical Students? A Cross-Sectional Study, Xiao C. Zhang, Sara A. Belko, Andrew J Monick

Department of Emergency Medicine Faculty Papers

Background Diagnostic errors affect patient safety and lead to high costs. Cognitive bias is a key source of diagnostic error, and the framing effect poses a particular clinical challenge. The extent to which individual factors affect susceptibility to the framing bias is unclear, and the role of expertise in particular is contested across the literature. Objectives This study investigated the effects of framing bias on diagnostic reasoning among medical students. We hypothesised that the effects attributable to framing would be mediated by the number of years of medical education completed. Methods Participants were randomly assigned on an automated basis with …

Development Of Comforturn: A Smart Mattress System For Automated Patient Repositioning Using The 4d Development Model (A Concept Paper), Khin Thandar Aung, Nur Alya Farhana Suhaimi, Nik Nur Aisyah Nik Sukriman, Nurul Ain Zakaria, Nur Adila Zaidi, Khin Thuzar Aung, Rafiza Abdul Razak

Individual Open Access Articles

Pressure ulcers, also known as pressure sores, are a common and preventable complication among mobile patients, resulting from sustained pressure on specific body areas. Manual repositioning is the primary strategy for prevention, but it is physically stressful, time-intensive, and not uniformly performed by care providers. Ripple mattresses provide passive pressure redistribution; however, manual tuning is still necessary and requires an automated approach. This concept paper discusses the design of Comforturn, a smart mattress system capable of automating patient turning with a programmable side tilt and wave-like motion. The goal is to lessen caregivers' work burden and increase patient safety and …

How Social, Behavioral, And Policy Factors Impact Water Satisfaction And Management In Urban Areas, Rafi Haikal, Thoriqi Firdaus, Siti Hilya Nabila, Rizqi Shafira Chairunnisa

Journal of Environmental Science and Sustainable Development

The issue of water management in Indonesia’s specific urban contexts, specifically in Surabaya as an industrial hub and Bali as a tourist destination, is of paramount importance due to its impact on public health and environmental sustainability. This study analyses water management and conservation factors by comparing two distinct urban areas. The research design employs Partial Least Squares Structural Equation Modelling (PLS-SEM), which involves a specialised approach for analysing the complex relationships between variables. The results of the analysis indicate that community attitudes in Surabaya, facilitated by infrastructure and technology, significantly predicts intention to perform (β=0.334, p<0.001) and water management satisfaction (β=0.409, p<0.001). In contrast, collaboration with the government enhances environmental constraints (β=0.285, p<0.003) and water management satisfaction (β=0.140, p<0.044). In Bali, where water management is based on traditional practices, community attitudes do not significantly affect water management satisfaction (β=0.095, p>0.431). Still, perceived …

Short Term Hemodynamic Effects Of Atrial Fibrillation In A Closed-Loop Human Cardiac-Baroreflex System, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, Mayuresh V. Kothare

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Atrial fibrillation (AF) remains the leading cardiac cause of stroke and AF-related death rate in the United States has been increasing for over twenty years. While the effect of standalone AF on heart rate is well established, there is a lack of clarity on its impact on other critical hemodynamic metrics. This is ostensibly due to interaction with other common comorbidities, especially hypertension. In addition, AF has a complex relationship with the state of the baroreflex. Evidence indicates that baroreflex sensitivity (BRS), the ability of the intrinsic cardiac control system to initiate parasympathetic response, is suppressed during AF. Therefore, a …

Transcriptome And Gene Expression Profiling Of Sweetpotato Responses To Nitrogen And Phosphorus Deficiency During Storage Root Formation, Lisa I. Arce

LSU Doctoral Dissertations

Nitrogen (N) and phosphorus (P) are essential macronutrients required by plants for normal growth and development. In sweetpotato [Ipomoea batatas (L.) Lam.], these nutrients are the most limiting factors affecting both yield quality and quantity. While most research focuses on agronomic responses and genomic analyses, limited research has examined transcriptomic responses to nutrient stress in sweetpotato. Here, we employed next-generation sequencing to investigate the molecular mechanisms underlying N and P deficiency responses in cultivar 'Bayou Belle' (BB). We utilized root tip tissue and investigated responses during the critical stage of root development and storage root formation at 5, 10, …

Use Of Growing Degree Days To Model The Dynamics Of Aboveground Biomass And Nitrogen Accumulation Of Winter Cover Crops, M. Pessotto, Trenton Roberts, C. Dos Santos, K. A. Hoegenauer, M. Bertucci, W. J. Ross, M. Savin

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Cover cropping is an important management practice that can benefit the cash crop and the environment. Plant species, weather, and cover crop termination influence biomass production and N fixation potential. This study was conducted to determine optimal termination dates for production systems in Arkansas based on growing degree days (GDD) for eight different cover crop species: Austrian winter pea (AWP) (Pisum sativum), balansa clover (Trifolium michelianum), barley (Hordeum vulgare), black-seeded oats (Avena sativa), common vetch (Vicia sativa var. Cahaba), cereal rye (Secale cereale), crimson clover (Trifolium incarnatum), and hairy vetch (Vicia villosa). Field studies were conducted at three research stations …

Existence, Uniqueness, Stability And Exact Expression Of Periodic Traveling Wave Solutions Of The Higher-Order Cubic-Quintic Nonlinear Schrödinger Equation, Nan Wang, Yuqian Zhou, Zhijun Qiao

School of Mathematical & Statistical Sciences Faculty Publications

In this paper, the high-order cubic-quintic nonlinear Schrödinger equation is considered. By overcoming the difficulties caused by its non-integrability, we completely explore the existence, uniqueness and stability of the limit cycle of the equation. It enables us to accurately give the explicit parameter representation of its periodic wave solution in a special form for the first time. These results provide not only a new idea of obtaining periodic solutions in complex nonlinear systems, but also the important theoretical support for understanding related wave phenomena.

Examining The Evolution Of Coaches Issues In Interscholastic Sport, Tyler J. Ratts, Eric W. Forsyth, Zachary C. T. Evans, James E. Johnson, Michael Fraina, Warren A. Whisenant

Global Sport Business Journal

Central to interscholastic athletic programs are coaches who directly affect the developmental outcomes experienced by student-athletes through their participation (Blanton et al., 2024; Grant, 2024; O’Boyle, 2014). Forsyth et al. (2022) analyzed the key issues perceived by athletic administrators to affect the coaching position, with Coaches Education rated as the single most important issue and Finding Coaches and Retaining Coaches also deemed to be of very high importance. Over time, the coaching role has continued to evolve, as increased role demands (Ratts, 2025), changing stakeholder expectations (Johnson et al., 2019; Stoffer et al., 2021), and growing burnout and turnover (Martin …

The Athlete’S Nil Playbook: The Complete Guide To Owning And Profiting From Your Name, Image, And Likeness, Kelly Brummett

Global Sport Business Journal

This review discusses The Athlete's NIL Playbook: The Complete Guide to Owning and Profiting from Your Name, Image, and Likeness. Though aimed at high school and college students and their parents, the book is a practical guide for anyone interested in learning more about and navigating the Name, Image, and Likeness (NIL) marketplace. With examples from current and former student-athletes' lived experiences, Dosh offers guidance for developing a personal brand, contacting sponsors, and seeking NIL opportunities beyond social media marketing. In addition, Dosh shares her legal experience to highlight potentially one-sided contract terms and key questions to ask before signing …

Stay To Play: Multi-Level Stakeholders And Motivation In Youth Sports Tourism, Brumby Mcleod, Ph.D., John Grady, Ph.D.

Proceedings of the Recreation Experience Community Network Research Symposium

In this study, the stay to play model of hosting elite youth sports events was investigated by exploring the various stakeholder perspectives in staging youth sport events, specifically soccer. This research explored the motivations and gaps among the event organizers, the housing authorities (booking agencies), governing bodies and leagues, as well as the destination marketing organization. This study explored the relationship, unique value proposition, and gaps between the services provided by the stay to play organizers and participants. By exploring these concepts, a better understanding of the stay to play model is achieved, and destination marketers and management associations can …

Sun, Fun, And Structure: What Resort Activity Schedules Reveal, Phileshia Dombroski, Ph.D., Kayla D. Mohney, Ed.D., Rebecca L. Moriarty, Ava Beal, Libby Scanlon, Emily Bailey, Cyan N. Kvacky

Proceedings of the Recreation Experience Community Network Research Symposium

Daily activity schedules are central to the guest experience in resort environments, guiding participation, communicating brand identity, and structuring leisure time. This mixed-method content analysis explored how resorts across the United States design and present these schedules, emphasizing accessibility and program diversity. Eighteen publicly available resort activity schedules were evaluated using accessibility tools (PAC 3, Adobe Acrobat, WCAG 2.2) and coded for 4,166 individual activities across eight categories. Findings revealed moderate adherence to accessibility standards. Most schedules met minimum font size and color contrast guidelines, but only 25% were compatible with screen readers and 80% lacked alternative text or structural …

Perceived Value Of Sport And Recreation In Aruba: Resident Perceptions Of Health, Lifestyle, And Physical Activity, Stephen L. Shapiro, Andy Gillentine, Jo-Anne Croes, John Wardlaw

Proceedings of the Recreation Experience Community Network Research Symposium

Sport and recreation play an important role in shaping community well-being, particularly in small island nations where health and tourism are integrated. This study examines how Aruban residents perceive the value of sport and recreation and how these perceptions vary based on the type of activity and children’s participation in these activities. A mixed-methods design was used across two phases. Phase I employed focus groups with residents, educators, and government stakeholders to explore themes of health, community impact, and education. Findings emphasized concerns over inactivity and identified sport and recreation as essential to promoting healthy lifestyles, sense of community, and …

Drivers Of Policy Support And Political Consumerism Behavior Among Water Recreationists, Mina Kim

Proceedings of the Recreation Experience Community Network Research Symposium

Individuals who engage in water-based recreation share a distinct bond with water quality due to their direct contact with aquatic environments during leisure activities. Increasing concerns about water quality have led to a rise in research exploring how environmental conditions and perceived risks shape environmental attitudes and conservation actions. However, it remains uncertain whether water recreationists extend their conservation efforts beyond those directly tied to their activities. To explore this issue, the present study investigates whether water-based recreationists in South Carolina support more stringent water management policies and engage in political consumerism behaviors, such as boycotting and buycotting. Data were …

From The Field To The Future: How Experiential Learning Supports Student Success, Joshua Carroll, Ph.D.

Proceedings of the Recreation Experience Community Network Research Symposium

Field Experiences are often considered extracurricular, and not always a part of traditional college programs. However, these experiences can provide unique opportunities for learning, increase student confidence, broaden student perspectives of their chosen profession, and connect students with their environments, professors, and classmates. Because these programs often require a deep commitment from faculty, administrators, and the students, it is sometimes difficult to justify the resources required to successfully implement these courses. This project sought to identify several of the impacts that a field course may have on students, and to summarize these findings into sharable data for potential college and …

How Did The Pandemic Change The Role Of Recreational Waters In Bringing Visitors? Analysis Of South Carolina Mobility Big Data, Seonjin Lee, Lori Pennington-Gray, Ph.D.

Proceedings of the Recreation Experience Community Network Research Symposium

The COVID-19 pandemic had a profound impact on nature-based recreational activities. Outdoor recreation became popular as an alternative to international travel with less risk of contagion. However, the question remains whether there was an enduring change in the role of natural resources in driving visitors. This study investigates the relevance of recreational waters, particularly lakes and beaches, to changes in patterns of domestic visitors to South Carolina between 2019 and 2023. All counties showed growth in recreational visitors, as well as diversification of visitors. However, the magnitude of the increase showed a significant difference based on geographical factors. Eight coastal …

Fall 2025 Full Issue, Undergraduate Research

PANDION: The Osprey Journal of Research and Ideas

No abstract provided.

Spiny Orb Weaver, Jasmine M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

This scientific illustration depicts the spiny orb weaver spider (Gasteracantha cancriformis), a distinctive arachnid known for its characteristic hardened, spiny abdomen. Spiny orb weaver spiders enjoy warm, tropical, and subtropical environments and are primarily found in the Southeastern U.S., the Caribbean, and South America. They live in wooded areas, citrus groves, and shrubby gardens. I’ve encountered spiny orb weaver spiders in my food forest where they like to set up their orb-shaped webs and feast on flies, mosquitoes, and moths.

This scientific illustration depicts the spiny orb weaver spider (Gasteracantha cancriformis), a distinctive arachnid known for its characteristic …

Darkling Beetle, Jasmine M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

Darkling beetles (Tenebrio molitor) are holometabolic insects. Darkling beetle is the common name of the large family of beetles Tenebrionidae which has more than 20,000 species. The T. molitor species gets its name from the yellowish appearance of the larvae. During its lifespan, a darkling beetle experiences a complete metamorphosis in four distinct stages: Egg, larva, pupa, and adult. The eggs hatch within 4 to 19 days after the female oviposits. It takes about 3 – 4 months for an egg to develop into an adult, or the beetle stage.

During the adult stage, the beetles are initially whitish and …

Horseshoe Crabs, Jessie M. Roncevic

PANDION: The Osprey Journal of Research and Ideas

Horseshoe crabs (Limulus polyphemus) are fascinating animals known as “living fossils.” Older than dinosaurs, horseshoe crabs are arthropods, closely related to spiders and scorpions. Many shorebirds, including red knot, depend on the eggs of horseshoe crabs during migration. Horseshoe crabs are captured and bled alive for their blue blood. Rich in limulus amebocyte lysate (LAL), their blood is used for the Limulus Amebocyte Lysate (LAL) test, which is used worldwide to detect bacterial toxins in pharmaceuticals and medical devices.

Horseshoe crabs have an intricate anatomy, so I spent a lot of time researching it before I started drawing them. When …

Floridians, Michael Anglim-Lindros

PANDION: The Osprey Journal of Research and Ideas

The purpose of this piece is to explore species present in Florida by depicting native species alongside commonly seen non-native ones. I decided to focus on mammals, specifically those I have personally observed while living in North Florida. By illustrating their unadorned skeletal remains, I hope to inspire viewers to consider the similarities, differences, and relationships among these organisms, as well as the lives they lead on shared land.

The species depicted in this piece are (clockwise from middle) Homo sapiens (human) - non-native; Tadarida brasiliensis (Mexican free-tailed bat); Dasypus novemcinctus (nine-banded armadillo); Sciurus niger shermani (Sherman’s fox squirrel); Odocoileus …

Blue Bottle, Prathna Nirav Patel

PANDION: The Osprey Journal of Research and Ideas

This piece consists of a series of individually shaped bottle forms, connected by a shared base and continuous surface. It is influenced by repetition, using similar forms differing in shape, height, and proportion to create unity and visual balance. The repetition of related shapes creates visual rhythm, while the differences between them add interest. This contrast between balance and variation reflects my interest in exploring how uniformity and difference can exist in a single object. I threw seven individual bottle forms on the wheel and arranged them in a straight line to highlight the contrast between the linear arrangement and …

Papernest Media: A Collaborative Multimedia Research Project, Susie V. Mabry

PANDION: The Osprey Journal of Research and Ideas

Papernest Media is a collaborative multimedia research project that contextualizes the history and contemporary status of insect commodities as traditional food, tourist fare, and natural dye in Oaxaca, Mexico. Our interdisciplinary team of Anne E. Pfister, PhD in Applied Medical Anthropology, Alex Kledzik, BA in Sociology and Susie Mabry, UNF International Studies, came together in 2024 to produce a short film accompanying the exploratory phase of a larger ethnographic investigation. In July 2024, we traveled to Oaxaca during a peak season and the annual Guelaguetza festival to investigate the touted sustainability of edible insects in a region known for its …

Juntos Hacemos El Cambio Por Nuestros Mares, Alanis N. Davila Marquez

PANDION: The Osprey Journal of Research and Ideas

Notas preliminares

Juntos hacemos el cambio por nuestros mares es una obra de teatro escrita colaborativamente por el curso IDS 1932 (FYE) Teatro para la salud, de la profesora Dr. Nuria Ibáñez y representada por la clase el 3 de noviembre de 2024 en Museum of Contemporary Art de Jacksonville, producida por las profesoras Dr. Maureen McCluskey y Dr. Nuria Ibáñez. La obra reflexiona sobre la relación entre nosotros los humanos y el océano, explorando profundamente cómo nuestras acciones afectan la salud de los ecosistemas marinos y, al mismo tiempo, nuestra propia salud. Al escribir la pieza buscábamos traducir las …

Probiotic Intervention In Managing Chronic Stress, Bianca Opdenbosch

PANDION: The Osprey Journal of Research and Ideas

Chronic stress can induce gut dysbiosis which contributes to the dysregulation of the gut-brain axis and leads to anxiety and depressive-like symptoms. The gut-brain axis relies on nervous, immune, and endocrine interactions. Gut dysbiosis, an imbalance within the gut microbiome, disrupts gut-brain communication, impairing gut barrier integrity, inflammation regulation, and hormonal and neurotransmitter production. These gut changes contribute to mood disorders resulting from stress, and thus it is important to implement dietary interventions, like probiotics, to help mitigate these effects. Research highlights the potential of probiotics to act as an intervention to combat stress-induced gut dysbiosis and replenish beneficial bacteria …

Rewilding The Built Environment: Navigating Economic, Political, And Social Barriers To Urban Ecological Restoration, Carly E. Smith

PANDION: The Osprey Journal of Research and Ideas

Urban rewilding offers a nature-based approach to restoring ecological processes in cities while advancing climate resilience, biodiversity, and public well-being. Unlike conventional green infrastructure, rewilding allows ecosystems to develop with minimal intervention, emphasizing succession, complexity, and long-term adaptability. This paper examines the political, economic, and social factors that frame how rewilding is understood and implemented in urban planning. Governmental frameworks often prioritize order, predictability, and short-term results, making it difficult to accommodate the uncertainty and ecological complexity that rewilding requires. Economic models struggle to capture its long-term value, frequently overlooking ecosystem services or reconciling competing land uses. Social perceptions of …

Listening To Wrong Beliefs: Being A Virtuous Agent In Contexts Of Disparity, Madison K. Mendiola

PANDION: The Osprey Journal of Research and Ideas

Using the concept of intellectual humility (IH) described by Whitcomb et al. (2021) and their application of IH in contexts of disparity, I will be furthering the discussion of the importance of IH when engaging with the other side. Although there are intellectual harms associated with being too open-minded, and moral concerns about being a listener to harmful ideas, I argue that epistemic agents risk committing an intellectual error when they don’t try to understand the beliefs of the in-the-wrong party. Even in contexts of disparity, you should be able to understand the other party’s belief-forming methodologies, which is compatible …

Analysis Of Mct-1 Expression In Mouse Neural Retina In Response To Chronic Inflammation, Ian W. Ronson

PANDION: The Osprey Journal of Research and Ideas

Chronic inflammation is a current public health concern as it is linked to the etiology and symptoms of numerous diseases, for example diabetic retinopathy (DR). In the case of DR, inflammation leads to dysregulation of the blood retina barrier causing retinal hemorrhage and macular edema leading ultimately to irreversible vision loss. MCT-1 is critical for the survival of photoreceptor cells because MCT-1 forms protein complexes with Basigin, a cell-cell adhesion protein, that enables Müller glial cells to efficiently provide lactate as a high energy fuel source. Previous studies have shown chronic inflammation reduces Basigin expression in the retina and that …