Digital Commons Network^™

Genomic And Metabolic Network Characterization Of Fusarium Species, Hend Hussain Mueenuddin

Theses

Fusarium covers the wide genus of fungi with over 400 species that are key in agricultural and medical practice. The purpose of the current study was to perform a comprehensive genomic profiling of the 19 Fusarium species that were captured in the National Centre of Biotechnology Information (NCBI) database. The study was made to make a comparison of the data, based on the descriptive statistics of every species, with graphical representation images enabling clear demonstration of the numbers. The study indicated that the chromosomal numbers were in the range of 0-15, the gene count was roughly 11000 -19000, while that …

The Simulation Of Hyperspectral Observations By The Upcoming Spacecraft "Arab Satellite 813", With The Radiative Transfer Model Sciatran, Sara Maher Alhasan

Theses

The Arab Satellite 813, which is scheduled to be launched in 2025/2026 by the UAE Space Agency, is set to increase earth observation and monitor the climate across the middle East and North Africa (MENA) region. This study uses the SCIATRAN radiative transfer model which was originally developed for the Envisat mission to simulate the hyperspectral observation specifically tailored for the satellite's payload. Using calibrations that were used by the previous research in their SCIATRAN V4.6 study and adjusting parameters like the Leaf Area Index (LAI), a simulation which agreed robustly with the benchmarks set by the previous research was …

Microstrip Antenna Design Based On Ai And Machine Learning, Waleed Mohamed Sha Moulavi

Theses

Microstrip patch antennas (MPAs) rely on precise impedance matching for efficient power transfer between the antenna and feed line. This is often achieved using a number of different techniques, one of which is the quarter-wavelength transformer (QWT). While commercial electromagnetic (EM) solvers offer robust optimization capabilities, they often operate as "black boxes" without providing physical insights into parameter interdependencies. Furthermore, this thesis focuses on the specific scenario where the antenna input impedance is purely real. To address the lack of explicit design relationships for these specific conditions, this thesis develops and comparatively evaluates artificial intelligence (AI) models for QWT width …

It’S A Balancing Act: Analyzing The First Fair Use Factor, Taylor Gluckman

Fordham Law Review

Fair use has always been an important element of copyright law. The first fair use factor, “the purpose and character of the use,” has become especially important after the U.S. Supreme Court’s decision in Andy Warhol Foundation for the Visual Arts, Inc. v. Goldsmith. The “purpose and character” is typically analyzed by determining if a secondary work is “transformative,” but lower courts do not agree on what it means to be transformative. There is also disagreement on how to balance a secondary work’s transformative nature with its commercial nature when deciding whether the first factor favors fair use.

This …

Rank-Based Learning: A Novel High-Throughput Algorithm Resilient To Missing Data And Effective For Datasets With Small Sample Size, Lulu Song, Hamid Khoshfekr Rudsari, Johannes F Fahrmann, Jody Vykoukal, Sam Hanash, James P Long, Kim-Anh Do, Ehsan Irajizad

Faculty, Staff and Student Publications

High-throughput omics data present challenges for binary classification due to platform variability, batch effects, missing values, and high dimensionality. This study presents a novel Rank-Based Learning (RBL) method that leverages relative feature rankings to improve robustness and generalizability. We evaluated RBL against established methods like Logistic Regression (LR) and Random Forest (RF) using simulated data and two real-world plasma proteomics datasets: early-stage small cell lung cancer (SCLC) and duodenopancreatic neuroendocrine tumors (dpNET) in patients with Multiple Endocrine Neoplasia type 1 (MEN1). In simulation experiments, RBL outperformed LR under conditions involving batch effects, missing data, and varying numbers of true differential …

Phase 2 Study Of Monotherapy With Pembrolizumab For Advanced Adrenocortical Carcinoma, Brenda Chahla, Bettzy Stephen, Juhee Song, Vania Balderrama-Brondani, Feyza Yaylaci, Matthew T Campbell, Aung Naing, Mouhammed Amir Habra

Faculty, Staff and Student Publications

Introduction: Adrenocortical carcinoma (ACC) is a rare cancer with suboptimal response to chemotherapy. The role of immunotherapy in ACC management is evolving.

Methods: An investigator-initiated, open-label, phase 2 clinical trial was performed to ascertain the activity and safety of monotherapy with pembrolizumab (a humanized monoclonal anti-programmed cell death protein 1 antibody) in patients with advanced ACC. This study was part of a basket clinical trial (ClinicalTrials.gov ID: NCT02721732). Study participants were enrolled from August 15, 2016, until December 7, 2020. Pembrolizumab (200 mg) was administered intravenously every 3 weeks. All other lines of therapy, including mitotane, were stopped before …

Replication-Competent, Tumor-Specific Immuno-Gene Vectors Allow For Exchange Of Transgenes And Lead To Viral Persistence Following Iv Administration, Lee S Rosen, Christian Ottensmeier, Maria Hawkins, Aung Naing, Guru Sonpavde, Brian A Van Tine, Eileen E Parkes, Sean M O'Cathail, Rui-Ru Ji, Matthew Thomas, Andrea Stacey, Maria Stella Sasso, Oliver Rosen

Faculty, Staff and Student Publications

Introduction: Enadenotucirev (EnAd) and successor transgene-armed Tumor-Specific Immuno-Gene (T-SIGn) vectors are replication-competent, blood-stable viral vectors that traffic to tumor sites following intravenous (IV) administration. Following initial proof of mechanism for this immunotherapy modality, there is a need to identify a safe dosing approach, understand whether transgenes affect tolerability, and determine how to measure exposure and pharmacodynamic effects.

Methods: Safety data from multiple phase 1 trials were aggregated to assess various dosing regimens and toxicities, including those that may be associated with transgene arming. Viral delivery to tumors, peripheral viral persistence, transgene expression, and cytokine responses were also assessed and compared …

Testing If Vitamin K1 Reduces The Progression Of Non-Severe Calcific Aortic Stenosis: Design And Rationale Of The Prevention Of Aortic Stenosis Progression Phylloquinone Ossification Reduction Trial (Passport), William A. Courtney, Jarryd Walker, Aindreas Dorai-Raj, Tom Gilbert, Adil Rajwani, Jamie W. Bellinge, Jonathan M. Hodgson, Graham S. Hillis, Carl J. Schultz

Research outputs 2022 to 2026

Aims Calcific aortic stenosis (CAS) is the most common heart valvulopathy in high-income countries. There is no known treatment for CAS other than replacement of the valve in severe, symptomatic disease. Observational studies and a small openlabel randomized trial have reported that vitamin K1 supplementation may reduce the progression rate of calcification and obstruction in CAS. Methods and results 3PASSPORT(ACTRN12622000447752) will be a prospective, randomized, double-blind, placebo-controlled clinical trial investigating if nutritional supplementation with 10 mg of vitamin K1 can reduce the rate of valvular calcification and haemodynamic progression in CAS. Patients identified to have mild or moderate CAS based …

More Alike Than Not: The Open Access Preferences Of Humanities Scholars, Rachel E. Scott, Ana Dubnjakovic

Faculty and Staff Publications – Milner Library

Several studies have noted that humanists have not been as quick or enthusiastic in their adoption of Open Access (OA) as their colleagues in other disciplines. This article leverages the Ithaka S+R US 2021 Faculty Survey to provide contextualized analysis of the OA and Open Education Resources (OER) preferences of humanities scholars, as well as some practices related to OA and OER, relative to their colleagues in other disciplines. Findings suggest that although humanists do stand apart in many OA preferences, the small effect sizes render these differences less important than previously suspected. The implications of these findings are considered …

Sailing Into And Against The Wind: Principled Opposition To And Acceptance Of Transformative Agreements, Rachel Scott, Mitchell Scott, Ben Rawlins, Lindsey Skaggs

Faculty and Staff Publications – Milner Library

This session explores different approaches to transformative agreements (TAs) at a Carnegie R1 University and a Carnegie R2 University, offering a comparative look at how these agreements shape faculty publishing experiences and the management of article processing charges (APCs). The R2 has adopted TAs to expand read access and support open access (OA) publishing, while the R1 has taken a principled stance against TAs, citing concerns about their role in perpetuating the serials crisis and questions of long-term sustainability.

Presenters from both institutions will share institutional and library motivations, as well as faculty feedback, highlighting real-world challenges related to APC …

Skin Soft Tissue Infection: Antibiotics For Abscesses, Children's Mercy Kansas City

Clinical Critically Appraised Topics

No abstract provided.

Research Review: "Structure In Transition: The Role Of Structure In Facilitating Workplace Efficacy And Belonging For Military Veterans", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

Employment transitions necessitate a degree of uncertainty and lack of control, which may present a challenge to succeeding and belonging at a new organization. The present research tests ideas derived from compensatory control theory which posits that people may seek external structure to help exert control over their lives when they experience a lack of control in an important life domain – and that this can aid in their goal pursuit. Across three studies, we explore whether the perception of a higher degree of organizational structure can help employees compensate for uncertainty and lack of control and facilitate transitioning employees’ …

Systemic Racism In Canadian Healthcare: A Policy And Equity Analysis, Kola Adegoke, Abimbola Adegoke, Deborah Dawodu, Temitope Kayode

Health & Biomedical Sciences Faculty Publications

Background: In Canadian healthcare, systemic racism subverts commitment to universal coverage by building inequities into the system of governance, regulation, and clinical practice. Although racial disparities have been documented, little attention has been paid to how institutional structures perpetuate these inequities.

Objective: This study critically examines the organizational aspects of racism in the Canadian healthcare system. It aims to identify structural obstacles faced by racialized patients and foreign-trained physicians and to provide policy recommendations grounded in evidence.

Methods: The authors employed a narrative review framework for qualitative analysis of documents. Public inquiries (eg, Truth and Reconciliation Commission and Viens Report), …

An Analysis Of Renewable Energy Capture Utilization For Mpulungu Harbour, Dorica Nayame

World Maritime University Dissertations

No abstract provided.

Feasibility Of Onshore Power Supply For Port Electrification : A Business Case For Ports, Atti Abbas Shah

World Maritime University Dissertations

No abstract provided.

E-Counseling Platform For Seafarers’ Sound Mental Health : Prospects And Challenges To Implement Globally On-Board Ships, Farzana Yasmin

World Maritime University Dissertations

No abstract provided.

Green Shipping Corridors In West Africa : Overcoming Barriers And Unlocking Opportunities For Maritime Decarbonization, Bismark Owoahene Acheampong

World Maritime University Dissertations

No abstract provided.

Emerging Policies On Marine Biodiversity Beyond National Jurisdiction Governance, Jessie Neta Jeffrey

World Maritime University Dissertations

No abstract provided.

Access To Justice For Seafarers In Tanzania : Legal And Institutional Barriers, Sadath Khalipha Kibwana

World Maritime University Dissertations

No abstract provided.

The Ratification And Implementation Of The International Maritime Organisation (Imo) Instruments : A Social And Policy Persepctive On Maritime Governance In Fiji, Miriama Latianara

World Maritime University Dissertations

No abstract provided.

Precarity At Sea : Legal Challenges And Protection Of Maritime Workers, Wenjuan Li

World Maritime University Dissertations

No abstract provided.

The Multidoor Courthouse System In Commercial Maritime Disputes : Enhancing Access To Justice And Dispute Resolution Efficiency In Nigeria, Adetola Aderonke Oduwole

World Maritime University Dissertations

No abstract provided.

An Analysis Of The Legal And Policy Challenges For Developing Countries In Implementing The Imo’S 2023 Ghg Strategy : A Case Study Of South Africa And Indonesia, Mduduzi Godson Qwabe

World Maritime University Dissertations

No abstract provided.

Preparedness And Response To Oil And Biofuel Spills : A Case Study Of The Western Indian Ocean, Soifoine Abdillah

World Maritime University Dissertations

No abstract provided.

Scaling Up Cooperative Multi-Agent Reinforcement Learning, Minghong Geng

Dissertations and Theses Collection (Open Access)

Multi-agent systems (MAS) involve multiple autonomous agents that coordinate their actions to achieve shared or competing objectives in dynamic environments. Over the past decade, multi-agent reinforcement learning (MARL) has emerged as a powerful paradigm for enabling collaborative behaviors among autonomous agents within MAS to solve complex tasks. This dissertation discusses a critical scalability gap that exists between current MARL capabilities and real-world deployment requirements. Most existing MARL research focuses on small-scale laboratory problems, often struggling to coordinate large agent populations and facing challenges with extended decision-making horizons. In contrast, many real-world applications demand coordination among hundreds or thousands of agents …

Inventory Assortment Model For Retailers With Multi-Level Substitution Of Products, Gian Paolo G. Guiao, Gabriel John L. De Leon, John Kenneth P. Punongbayan, Kathleen L. Baldoz, Ven-Rem Bill A. Pasion, Angelo C. Ani

Journal Article

Ensuring a sufficient inventory level at the retail stage of the supply chain is essential to meet customer demand. However, determining the ideal quantity of products to be ordered by a retailer is challenging when there is a substitution of products. This study addresses the occurrence of customers substituting products in the store in case of product unavailability by developing a two- phase stochastic optimization model. The first phase created a discretized demand profile, one of the novelties of this study, that allows customers to substitute up to two attempts. The second phase developed a mixed-integer program (MIP) model that …

Perceived Courier Service Quality On Online Sellers’ Intentions To Reduce Overpackaging, Freya Jiana T. Arellano, Marc Immanuel G. Isip

Journal Article

This study focused on understanding the intentions of Filipino online sellers to reduce overpackaging, recognizing their pivotal role in addressing packaging waste. Specifically, the study employed Ajzen’s Theory of Planned Behavior (TPB) and extended it by integrating Perceived Courier Service Quality (PCSQ) to explain Filipino online sellers’ intentions to reduce overpackaging. Additionally, the study examined the mediating role of TPB constructs in the relationship between PCSQ and these intentions. Quantitative data collected from 182 Filipino online sellers revealed positive intentions among these sellers to reduce overpackaging. Results from the Partial Least Squares – Structural Equation Modeling (PLS-SEM) identified Attitude and …

Strengthening Maritime Administration Via Blue Economy In Nigeria : For Sustainable Shipping And Ocean Governance, Ibrahim Adamu Badamasi

World Maritime University Dissertations

No abstract provided.

Port State Control In The Philippines : Addressing Challenges And Recommending Pathways For Enhancing Qualification And Operational Effectiveness, Kethlynn Mae Nadal

World Maritime University Dissertations

No abstract provided.

The Role Of Marine Spatial Planning (Msp) In Managing Conflicts Between Marine Resource Users In Tanzania, Ramadhani Juma Shausi

World Maritime University Dissertations

No abstract provided.