Orthogonal Comparison Of Nuclear And Mitochondrial Clonal Architectures In Hematologic Malignancies, Nehali Shah

Dissertations and Theses (Open Access)

Acute myeloid leukemia (AML) is a hematologic malignancy characterized by accumulation of mutations that disrupt hematopoietic differentiation and promote clonal expansion. Understanding how these mutations arise and evolve is essential for improving diagnosis, prognosis, and treatment stratification. Current methods are limited by either restricted genomic coverage (targeted panels) or low throughput and high cost (in single-cell whole genome sequencing, scWGS). An emerging alternative is the use of mitochondrial DNA (mtDNA) mutations as clonal markers.

This study aims to determine whether mitochondrial-derived clonal architectures correlate with nuclear-derived clonal architectures in AML, thereby evaluating mtDNA as a scalable orthogonal tool for lineage …

Ai: It's Not Going Away! Harnessing Ai To Enhance Learning In Nursing Education, D'Ann Wilson Somerall, Chris Hickman, William E. Somerall Jr.

Biennial Convention (CONV)

Artificial Intelligence (AI) has transformed learning, but to what extent? Is AI preventing students from using their creativity and knowledge? Is AI negating the development of scholarly writing skills? Do students understand the academic use of AI and the possibility of generating inaccurate information they may share with others, thinking it “came from the internet,” so it must be correct?

ChatGPT, an AI tool used extensively by college students, was released in November 2022. Multiple other programs have been released in the past two years, and more tools are launched daily. Sadly, many academicians have not embraced AI or developed …

Intersecting Civic Engagement Among Nurses With Service-Learning In Nursing Education, Carrie Rewakowski

Biennial Convention (CONV)

Following the timely declaration by the World Health Organization that 2020 was the “Year of the Nurse and the Midwife” (Howard, 2019), the profession of nursing was thrust into the national spotlight. Nurses can leverage this spotlight by using their voices to advance the health of those they serve through civic engagement. Civic engagement refers to involvement in significant activities that influence and shape society (Organization for Economic Cooperation and Development, 2024). Healthy People 2030 identified civic participation as a crucial element in Social Determinants of Health that includes both voting and volunteering (Pronk et al., 2023). With over 5.2 …

Nurses’ Role In Using Prayer As A Complementary And Alternative Spiritual Care Tool, Sonia H. Wisdom

Biennial Convention (CONV)

Praying is a spiritual and religious ritual that patients may use to support healing and cope with stress. Illness may challenge the patients’ ability to pray and nursing assistance is needed (Gad et al., 2022). Nurses are uncertain of their role in responding to patients’ prayer needs, as the use of prayer remains controversial (Nilsson, 2022).

This quantitative study explored nurses’ attitudes and perceptions of their role in praying. Data were collected from a self-selected sample of 2,688 RNs in the Florida Board of Nursing, using a 33-item 5-point Likert-scale questionnaire. Factor analysis extracted four subscales labeled as attitudes to …

Aligning Strategic Goals & Personal Growth: Innovative En-Renc Teaching Strategies At Raffles Hospital, Lilian S. M. Yew, Dira D. Haridas, Jai Vaishnavi D. Jayakumar, Hui Wen Ten, Nur Shida Binte Zainal Abidin

Biennial Convention (CONV)

The Enrolled Nurse Role Expansion Nursing Nurse Course (EN-RENC) at Raffles Hospital(RH) aligns training with strategic goals & individual development. It enhances patient care, operational efficiency, and financial viability while supporting career advancement & job satisfaction for enrolled nurses (ENs).

Purpose: Demonstrates alignment of strategic objectives and individual development via innovative teaching in EN-RENC.

Program Overview: EN-RENC equips ENs with advanced skills like intramuscular injections, wound dressing, venepuncture, & diabetic foot care, improving patient care & satisfaction^1,2. Upskilling ENs reduces dependency on agency staff & overtime, lowering labor costs & optimizing workflow.

Efficiency and Cost Savings: Enhanced EN …

Palliative Ventilator Withdrawal Algorithm: A Feasibility Quality Improvement (Qi) Project, Al-Zada Aguilar, Olivia Nicastro

Biennial Convention (CONV)

Managing respiratory distress during end-of-life (EOL) ventilator withdrawal poses significant challenges, particularly without structured algorithms or validated, reliable tools. This quality improvement (QI) project addressed these challenges by implementing Campbell’s ventilator withdrawal algorithm and the Respiratory Distress Observation Scale (RDOS), a validated, reliable tool for objective dyspnea assessment. This project sought to enhance care quality by evaluating process feasibility while addressing implementation barriers.

Dyspnea is a complex, subjective symptom frequently encountered during EOL ventilator withdrawal. Campbell’s algorithm provides a structured, individualized approach emphasizing prevention, early intervention, reassessment, and treatment while considering patient-specific factors such as illness severity and level of …

Governing Complexity: A Comparative Assessment Of Four Governance Models With Applications To Climate Change Mitigation And Adaptation, J. B. Ruhl, Niko Soininen, Barbara Cosens, Lance Gunderson

Vanderbilt Law School Faculty Publications

Responses to ongoing global climate change include economy-wide mitigation efforts and large-scale societal adaptation that demand novel approaches to governance. An array of innovative governance models has been proposed since the late 1900s and early 2000s as scholars observed inadequacies of government-centric and formal legal approaches to natural resource management, complexity and uncertainty, failures of neoliberal economic reforms, and cross-scale institutional arrangements. Four such models have come to dominate the solution-oriented discourse on climate change governance: adaptive governance, transition governance, transformation governance, and anticipatory governance. We compare these models in terms of their origin and applicability to deal with the …

Metabolic Dysfunction Caused By Dietary Oxylipins And The Environmental Toxicant Pfos, Jazmine Alexis Eccles-Miller

All Dissertations

Disruption of fat metabolism is a hallmark of metabolic disease. A liver enzyme, Cytochrome P450 2B6 (CYP2B6) is an anti-obesity enzyme that produced several omega-3 and omega-6 fatty acid metabolites that could contribute to metabolic diseases such as fatty liver disease. Two of these metabolites, 9-HODE and 9-HOTrE, may be associated with fatty liver. Mice were exposed to 9-HODE and 9-HOTrE to investigate whether they contribute to fatty liver disease under fasting conditions. A transgenic mice model expressing the human enzyme CYP2B6 was also fasted to determine if CYP2B6 leads to increased fatty liver under fasting conditions compared to a …

School Discipline Bylaws In Egypt: An Analysis Of The Framing Of Children’S Rights In Education (2014–2024), Noha Ekram Hassan

All Dissertations

This study investigates how Egypt’s School Discipline Bylaws (SDB), issued between 2014 and 2024, construct the language of discipline, children’s rights, and school governance. Using a Corpus-Assisted Critical Discourse Analysis (CADA) combined with interpretive Critical Discourse Analysis (CDA), the research identifies child-rights terminology within the five Bylaw versions, examines its relationship to the principles of the Convention on the Rights of the Child (CRC), and traces how these linguistic patterns change over time. The analysis also explores the discursive framing of discipline, sanctions, and agency, alongside a rubric-based evaluation of the SDB’s alignment with CRC principles of protection, participation, and …

The Influence Of Using Bibliotherapy And Cinematherapy Interventions On The Social-Emotional Competencies Of Middle School Students Identified As Gifted, Debra P. Wallace

All Dissertations

ABSTRACT

Adolescents encounter many stressors in their lives and need resources to help them navigate their challenges. Access to books and movies may help gifted middle school students find ways to cope with various stressors characteristic of gifted students. Bibliotherapy and cinematherapy interventions effectively offer gifted students emotional support for their mental, social, and academic struggles, since gifted students tend to avoid asking for help. In a rural southeastern town, a 2-month improvement science study included a Plan-Do-Study-Act cycle with gifted eighth graders. From December 2024 to January 2025, gifted students participated in an intervention program using bibliotherapy and cinematherapy …

Adoption Of The 4-H Thriving Model Of Positive Youth Development:A Case-Centered Examination Of 4-H Agents, Patricia Whitener

All Dissertations

ABSTRACT

Youth development professionals working in non-formal educational settings face the persistent challenge of translating evidence-based frameworks into effective practice. This explanatory sequential mixed-methods study examines how South Carolina 4-H agent/educators perceive and adopt the 4-H Thriving Model following mandatory statewide training. The study investigates the roles of professional identity, change readiness, and organizational factors in shaping innovation adoption decisions among Extension professionals who work with considerable autonomy within diverse community contexts.

The 4-H Thriving Model represents a comprehensive theory of change that connects program practices to the developmental processes that influence youth outcomes (Arnold and Gagnon, 2019). The model …

Advancing Life Cycle Assessment Of Mass Timber: Environmental Performance, Circular Design And End-Of-Life Strategies, Muzan Williams Ijeoma

All Dissertations

Mass timber has emerged as a leading candidate for low-carbon construction, offering the dual benefits of reduced embodied emissions and biogenic carbon storage. Yet, fully realizing its sustainability potential requires a comprehensive and context-specific understanding of its environmental performance across the entire life cycle, from raw material production to building operation and beyond end-of-life (EoL). This dissertation advances life cycle assessment (LCA) practices for mass timber by addressing critical challenges across multiple phases of its life cycle. This dissertation is comprised of three published papers, and two submitted manuscripts. First, I conducted a critical review and meta-analysis of mass …

Redefining The Script: Autonomy, Agency And Advocacy Among Black Women Educators, Racquel Plummer

All Dissertations

ABSTRACT

This qualitative study examines how Black women educators working with scripted curricula exercise autonomy, agency, and advocacy in elementary school contexts. Guided by interpretive phenomenology, the inquiry centers on lived experience and meaning-making. Data were collected through semi-structured interviews with ten educators, supplemented by reflexive journaling, member checking, and peer debriefing to enhance the trustworthiness of the findings. Analysis used iterative, thematic methods within a hermeneutic circle.

Two questions shaped the design. What beliefs and perceptions do Black women educators hold about autonomy, agency, and advocacy in scripted classrooms? How do they negotiate professional identity and role within mandates? …

Breeding For Disease Resistance In Melon And Watermelon, Venkata Rao Ganaparthi

All Dissertations

Watermelon and cantaloupe are two widely consumed cucurbits, but their acreage in the United States reduced by nearly 50% in last two decades. Fusarium wilt caused by a soil borne pathogen Fusarium oxysporum f. sp. niveum(Fon) race 2 is a major limiting factor in watermelon production as it reduces yields by 80%. Grafting watermelon plants onto the root stock of wild, disease-resistant varieties like ‘Carolina Strongback’ is the best strategy to manage Fon race 2. Though effective, this approach increases production costs.

Part of this dissertation focused on finding more sustainable, cost-effective solutions to control Fusarium wilt …

Cv: Sarah Drake Brown (Secondary Education, Elementary Education/Special Education), Sarah Drake Brown

Education Department Faculty Curricula Vitae

No abstract provided.

Motion Picture Reviews As Determinants Of Box Office Revenue In The Post-Covid Environment, Fernando Comiran, Velitchka D. Kaltcheva, Anthony Patino

Journal of Applied Marketing Theory

The decline in motion picture box office receipts and shortened release windows following the COVID-19 pandemic have placed heightened pressure on early performance as a critical determinant of commercial viability. Building upon earlier research suggesting that, as moviegoing frequency decreases, consumers are more likely to rely on audience reviews than critics’ reviews when making a decision to see a movie (Chakravarty et al., 2010), we examine which source of early reviews—professional critics reviews or audience reviews (WOM)—has an impact on early performance following the COVID-19 pandemic. We estimate a linear regression model using actual behavioral data—namely, eight years of motion …

When Environmental Provisions Acquire Primacy Over The Economic Interests – Case Comment Of The Preliminary Ruling In Case C-626/22 C.Z. And Others V Ilva, Katarzyna Błaszczak, Michał Krzaczek

Yearbook of Antitrust and Regulatory Studies

This case note analyses the Court of Justice of the European Union’s (CJEU) preliminary ruling in case C-626/22 (C. Z. and Others v Ilva). The Court interpreted the Industrial Emissions Directive (IED), ruling that Member States cannot derogate from minimum EU environmental requirements. The ruling established that environmental permits must consider all scientifically known harmful substances that could be emitted by installations. The Court also ruled that national regulations permitting repeated extensions to deadlines for installation operations, despite the identification of serious environmental and health risks, were incompatible with the IED. The CJEU’s interpretation confirms the primacy of environmental and …

Social Expectancies To Be Constantly Available And Productive As Antecedents And Consequences Of Burnout: A Longitudinal Bidirectional Investigation, Andree Hartanto, Meilan Hu, Adalia Y. H. Goh, Eddie M. W. Tong

Research Collection School of Social Sciences

Burnout has become increasingly prevalent in contemporary society, affecting not only those in the workplace but also students across various educational settings. The current study investigates whether the pervasive social expectancies to be constantly available and productive contribute to the onset and maintenance of academic burnout among university students. Using a 13-week longitudinal design and a random-intercept cross-lagged panel model, we examined the bidirectional association between social expectancies to be constantly available and productive and academic burnout. Our findings indicate that heightened social expectancies predict increases in emotional exhaustion and feelings of inadequacy in the following week. Furthermore, emotional exhaustion, …

Effectiveness Of Cognitive And Behavioral Interventions In The Treatment Of Schizophrenia: An Umbrella Review Of Meta-Analyses, Gabriel Xing Da Tan, Andree Hartanto, Zoey Khai Yee Eun, Meilan Hu, Kean J. Hsu, Nadyanna M. Majeed

Research Collection School of Social Sciences

Background: Cognitive and behavioral interventions have risen in popularity both as an adjunctive treatment to antipsychotic medication and as an alternative treatment for schizophrenia. With the growing number of such interventions, we performed an umbrella review to provide a comprehensive summary comparing the effectiveness of the different interventions among populations with schizophrenia. Methods: This umbrella review included meta-analyses evaluating cognitive and behavioral interventions for schizophrenia. Following PRISMA guidelines, the initial search yielded 4888 records, and after a three-stage screening procedure, 33 meta-analyses met the inclusion criteria for the final analysis. Results: Our findings from the 33 meta-analyses support the efficacy …

Contextual Stress Profiles And Trajectories Of Internalizing Symptoms Among Adolescents In Mexican Immigrant Families, Su Yeong Kim, Wen Wen, Kiera M. Coulter, Wei Xiang Sim, Tianlu Zhang, Jingyi Shen, Yang Hou, Yishan Shen, Ka I. Ip

Research Collection School of Social Sciences

Contextual stress experiences in early adolescents may predict distinct trajectories of depressive symptoms and anxiety across the course of adolescence. Data from 604 Mexican-origin adolescents collected from 2012 to 2020 (54% female; Mage = 12.92, SD = 0.92) showed that youth with high stress levels in multiple domains (Broadly Stressed) and those with high stress in language brokering domain only (Language Brokering Stressed) had similar levels of internalizing symptoms in early adolescence, and both groups reported higher stress than youth experiencing occasional levels of stress across domains (Occasionally Environmentally Stressed). However, youth in the Language Brokering Stressed group experienced slightly …

How Is South Africa's Black Economic Empowerment Policy (Bee) Addressing Historical Inequalities And Promoting Inclusive Development As Of 2024?, Nasim Uz Zaman

Southern African Journal of Policy and Development

South Africa’s Black Economic Empowerment (BEE) policy was introduced to dismantle apartheid-era economic disparities; however, its corporate-driven model has fostered symbolic compliance rather than substantive transformation. This study critically examines BEE’s structural limitations, specifically its failure to generate mass employment, its susceptibility to elite capture, and the prevalence of "fronting" practices. By juxtaposing BEE with affirmative action frameworks in Malaysia, India, and the United States, this research elucidates why ownership redistribution alone has failed to translate into inclusive economic mobility. Employing a qualitative policy analysis, this study synthesizes unemployment trajectories, implementation distortions, and systemic governance inefficiencies to highlight the constraints …

Vol. 8, No. 2 Cover

Southern African Journal of Policy and Development

No abstract provided.

Teaching Methods That Promote Medical Student Attendance: A Scoping Review, Jenny Mills, Sarah Keil, Pat W. Whitworth, Jamie Wiesmueller, Jeff L. Jackson

Library Faculty Scholarship

Background 

Medical student class attendance, especially traditional lectures, is on the decline. As faculty explore a variety of pedagogical approaches, understanding how to encourage attendance and engagement is critical. The purpose of this scoping review is to explore the literature to better understand the teaching methods that promote attendance.

Methods 

This scoping review was conducted as advised in the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis. Five databases were systematically searched for primary studies on teaching methods that motivated undergraduate medical students to attend or not attend in-person or online synchronous class sessions. A total of 1,313 articles were …

Mir-181a-5p Mediates The Effects Of Bmp4 On Intestinal Cell Proliferation And Differentiation, Chang Li, Yuning Zhou, Zhijie Yin, Yinping Jiang, Jinpeng Liu, Heidi L. Weiss, Qingding Wang, B. Mark Evers

Surgery Faculty Publications

The intestinal mucosa undergoes a dynamic process of continual proliferation, differentiation, and apoptosis. Delineating the mechanisms involved in intestinal epithelial cell (IEC) differentiation is crucial to our understanding of not only normal gut adaptation but also aberrant intestinal growth. Bone morphogenetic protein (BMP) signaling is a pivotal regulator of intestinal proliferation and differentiation. However, the molecular underpinnings of the BMP pathway in this context are not entirely known. Here, we show a key role for the BMP4/microRNA (miR)-181/glycolysis signaling pathway in the maintenance of intestinal epithelial cell proliferation and differentiation. Treatment with BMP4 increased the expression of enterocyte markers and …

Between Hard And Soft Power: A Historical Analysis Of U.S. Defense Diplomacy, Shuhei Takahashi

War, Diplomacy, and Society (MA) Theses

In recent years, countries around the world—those of Europe but also Japan, China, and Russia—have accelerated their efforts to use military assets as instruments of diplomacy. This trend has contributed to the rising prevalence of the term “defense diplomacy” in national security discourse. The United States is no exception. Its abundant military assets and its global network of bases clearly demonstrate that it is the world’s leading practitioner of defense diplomacy. Yet the United States lacks a clear strategic document outlining the concept. Moreover, because existing definitions remain theoretically ambiguous and methods for assessing the effectiveness of defense diplomacy initiatives …

Testing Microscopic Approaches For Cementochronology In The 21st Century Identified Skeletal Collection, Portugal, Amando Luis Montalvo Jr.

Theses and Dissertations

Age-at-death estimation is a key component to the creation of a biological profile in forensic anthropology. Acellular extrinsic fiber cementum annulations have been shown to correlate with chronological age. Cementochronology examines this correlation through the sum of the alternating translucent bands and opaque annuli, and the age of eruption of a tooth. While several microscopy techniques have been used, there is no consensus on the most optimal. This study will assess the reliability, precision and accuracy of three microscopy techniques: Brightfield (BF), Phase Contrast (PC) and Differential Interference Contrast (DIC). PC was the most reliable (rTEM= 10.4%), the most precise …

When Textures Trim Drag: Micro-Structures For Adaptive Drag Reduction And Flow Authority, Miguel Angel Olvera

Theses and Dissertations

Turbulent boundary layers are a major source of drag and performance loss. This thesis investigates Triangular Porous Texturing (TPT), apex-forward microstructures with optional bleed channels, as a passive concept for simultaneously reducing skin friction and strengthening boundary layer momentum near separation. Low-speed wind tunnel tests are conducted over tripped turbulent boundary layers on flat plates with three surfaces: a smooth baseline, a solid-crest TPT array isolating the knife-edge “slip-cut” effect, and a porous-bleed TPT array whose paired micro-channels vent a small fraction of the free stream. Time-resolved PIV provides wall-normal velocity fields; skin friction is inferred from near-wall shear, and …

Aged 539 Graduate Internship Report- Mount Whitney High School, Matthew C. Medeiros

Agricultural Education: Graduate Internship Reports

This project reviews the Mount Whitney High School Agricultural Education Program. Through evaluation of our program's needs, there was a lack of chapter promotion outside of social media. A chapter website was created to highlight Classroom, FFA, and SAE opportunities available to students in our program.

Alexander Asboth: Hungarian Separatist And Union Civil War General, Paul T. Brueske

Graduate Theses and Dissertations (2019 - present)

This thesis reveals the experiences of a Hungarian Separatist, Alexander Asboth, and how he applied those experiences in the American Civil War. It examines Asboth’s biography, his expansive view of the Union, and how he differed from many commanding officers in the Western theater. Moreover, this thesis illuminates Asboth’s military service, including his leadership of a diverse force at Barrancas, Florida, and adds to the understudied collaboration of foreign-born officers and Black soldiers in Gulf Coast Civil War history.

During the 1848 Hungarian separatist movement, Asboth served as an Army staff officer under the leader Lajos Kossuth. However, the separatists …

Application Of Graph Neural Networks On Phase Space Graphs For Cybersecurity, Parker H. Cole

Graduate Theses and Dissertations (2019 - present)

Non-linear phase space analysis may be used to represent time-series data as graph data with transitions between states in the time domain. By studying these transitions, we can predict anomalies within the system. Previous research has demonstrated success in learning from phase graphs for malware and seizure detection. These solutions either require extracting global features or converting the graph into an image for convolutional neural networks (CNNs), which adds a layer of complexity and limits the size and potential expressiveness of a graph. To sidestep current limitations, this study proposed Graph Neural Networks (GNNs) for analyzing phase graphs. GNNs do …