Digital Commons Network^™

Cv: Robert Sweet (Physical Therapy), Robert Sweet

Rehabilitation Sciences Department Curricula Vitae

No abstract provided.

Masthead

New England Classical Journal

No abstract provided.

Full Issue (52.2, Fall 2025)

New England Classical Journal

No abstract provided.

Research Progress In Enrichment Of Trace Elements Zinc And Selenium In Pleurotus Spp., Jing Zhang, Mengmeng Xu, Liting Zhao, Cui Li, Lei Chen, Song Ming, Zhongyang Ding

Journal of Food Science and Biotechnology

Zinc and selenium are essential trace elements for maintaining human normal physiological function.Deficiency of zinc or selenium can result in immune dysfunction,chronic diseases such as cardiovascular diseases and hyperlipidemia,and even increase the risk of cancer.The human body cannot independently synthesize these trace elements,which can only be obtained from the daily diet.However,natural food sources have low content of zinc and selenium,which is insufficient to meet the bod y’s needs.Therefore,developing fortified foods with trace nutrients is an important approach to meeting residents ’ requirements.Edible fungi serve as natural carriers for enriching trace elements and ideal dietary supplements.Pleurotus spp.,as a typical example,not only …

Construction And Optimization Of An Efficient Tyrosol Biosynthesis System In Escherichia Coli, Yizhe Xiong, Shougang Wang, Zhiming Rao, Meijuan Xu

Journal of Food Science and Biotechnology

[Objective ] An efficient biosynthetic system was constructed in Escherichia coli to achieve high-yield production of tyramine and its key derivative tyrosol.[Method ] Through the analysis of protein expression,enzymatic properties,and whole-cell catalysis results,tyrosine decarboxylase (TDC ) derived from Enterococcus faecalis was selected as the key enzyme for tyramine synthesis.Subsequently,tyramine oxidase (TYO ) was introduced to construct the TDC-TYO pathway for tyrosol production.Meanwhile,the LAAD-PDC pathway for tyrosol synthesis was established.A dual-enzyme co-expression system was established,and the effects of tandem enzyme order,production pathways,and key enzyme sources on tyrosol yield were analyzed.The recombinant strain B 1,carrying the plasmid pET 28a-EfTDC-TYO,was obtained through whole-cell …

Promoting The Synthesis Of Salicylic Acid In Escherichia Coli Based On Metabolic Engineering And Multi-Enzyme Cascade Strategy, Kai Wang, Xuewei Pan, Taowei Yang, Zhiming Rao

Journal of Food Science and Biotechnology

[Objective ] The production of the aromatic compound salicylic acid (SA) is limited by its inhibitory effects on enzymes related to cellular energy metabolism.This study aims to develop a strategy for avoiding the impact of SA on enzymes related to cellular energy metabolism and increase the yield of SA.[Method ] A highly efficient Escherichia coli strain was designed to improve SA production by optimizing metabolic pathways and enzyme systems.[Result ] The genome-scale metabolic model GEMS 1515 was employed to predict the key bottle necks in the phosphoenolpyruvic acid (PEP) pathway and SA biosynthesis pathways.The SA yield was successfully increased from …

Fermentation Technology Of L-Lysine Production By Immobilized Corynebacterium Glutamicum, Qingguo Liu, Hanjie Ying, Wenjun Sun

Journal of Food Science and Biotechnology

[Objective ] This study aimed to investigate the feasibility of the fermentation process for L-lysine production by immobilized Corynebacterium glutamicum.[Method ] Firstly,the effects of different volume fractions of seed medium on the fermentation stability of immobilized Corynebacterium glutamicum were examined.Subsequently,the impacts of immobilization carriers with different specifications on the fermentation performance were analyzed.Finally,a comparative analysis was conducted on the differences between the fermentation processes with free and immobilized Corynebacterium glutamicum.[Result ] The addition of 5% volume fraction of seed medium adequately sustained the growth and metabolic activities of Corynebacterium glutamicum.Higher volume fractions diverted carbon sources towards bacterial growth,thereby limiting product …

Reduction Of Methanol Content By Protoplast Fusion In Fruit Wine Yeast, Huixiang Zhang, Nan Lin, Jiaru Wu, Xin Cheng, Weiwu Liang, Shijun Yang

Journal of Food Science and Biotechnology

[Objective ] This study aims to breed a fruit wine yeast strain with low methanol production by protoplast fusion.[Method ] With yeast strains LAB and XR as parents,protoplast fusion was employed to breed the yeast strains for fruit wine fermentation with a low mass concentration methanol and a high volume fraction ethanol.The process of yeast protoplast preparation was optimized by single factor and orthogonal experiments with the formation rate,regeneration rate,and preparation rate of protoplasts as indicators.The parental protoplasts were inactivated by ultraviolet radiation and heating,and 35 g/dL PEG- 6000 was used for chemical fusion after inactivation.[Result ] The optimum conditions …

Effects Of Metschnikowia Pulcherrima And 24-Epibrassinolide On Postharvest Preservation Of Grapes, Jiayan Qu, Huiping Niu, Bowen Li, Xiao Wang, Lujun Wang, Zhumei Xi, Xuefei Wang

Journal of Food Science and Biotechnology

[Objective ] This study aims to investigate the effects of different treatments on the postharvest preservation of grapes.[Method ] The impacts of 0.4 mg/L 24-epibrassinolide (EBR ),1×109 CFU/mL Metschnikowia pulcherrima,and their combination (YBR ) on postharvest storage of ‘Shine Muscat ’ grapes were evaluated.[Result ] Compared with the control (CK) group,EBR,Metschnikowia pulcherrima,and YBR treatments effectively reduced the water loss rate,maintained the firmness,and delayed the declines in protopectin and stem chlorophyll content of grape.In the later storage stage,YBR treatment delayed the decrease in flavonoid mass fraction,which was 12.95% higher than that of CK group.At the same time,YBR treatment reduced the mass …

Application Of A Rapid Test Strip Method In Quantitative Detection Of Microorganisms In Chilled Meat, Yanzhen Zhang, Ning Liu, Wei Wang, Xianqi Yao, Laixue Ni, Yunguo Liu

Journal of Food Science and Biotechnology

[Objective ] This study aims to evaluate the feasibility of using the rapid test strip method for detecting key microbial quality control indicators in chilled meat,specifically the total plate count and Escherichia coli /coliforms.[Method ] The performance of the rapid test strip method was assessed through repeatability tests,and the national standard plate count method was used as the reference for method comparison.Statistical significance of the quantification results was analyzed by a t-test,and linear regression was adopted to analyze the correlation.[Result ] The repeatability deviation of the rapid test strip method (r≤0.25) met the requirements of ISO 4833—1:2013.No significant difference was …

Effects Of Single And Mixed Fermentation On Flavor , Composition , And Antioxidant Activity Of Soybean Whey, Taotao Wei, Qian Chen, Xiangjie Tao, Bin Tang, Fusheng Ren, Ping Hu

Journal of Food Science and Biotechnology

[Objective ] This study aims to explore the impacts of single strain fermentation and mixed fermentation on the flavor,composition,and antioxidant activity of soybean whey.[Method ] Gas chromatography-ion mobility spectrometry (GC-IMS ) was coupled with E-nose and high-performance liquid chromatography (HPLC ) to a nalyze the flavor and function of soybean whey fermented by the single and mixed strains.[Result ] Compared with single-strain fermentation by Limosilactobacillus fermentum HJS- 1 or Kluyveromyces marxianus HJS- 2,mixed fermentation (Limosilactobacillus fermentum HJS- 1 + Kluyveromyces marxianus HJS- 2) effectively improved the levels of functional substances and antioxidant activity of soybean whey.Compared with non-fermented soybean whey,mixed …

Efficient Catalytic Synthesis Of 5-Methylpyrazine- 2-Carboxylic Acid By Recombinant Escherichia Coli, Luxi Gan, Heng Gong

Journal of Food Science and Biotechnology

[Objective ] This study aimed to improve the yield and conversion rate of 5-methylpyrazine- 2-carboxylic acid (MPCA ) through biocatalysis.[Method ] Escherichia coli (E.coli）was used as the model organism to construct an MPCA synthesis system,and the whole-cell catalytic reaction conditions of recombinant E.coli were optimized.In addition,the parental host strain was subjected to ultraviolet mutagenesis for the screening of host strains tolerant to high mass concentrations of 2,5-dimethylpyrazine (DMP ).[Result ] The recombinant mutagenized strain could completely convert 10 g/L DMP to MPCA within 12 h in a 10 mL reaction system,achieving a yield of 12.9 g/L and a corresponding molar …

Goat Milk Formula Powder Ameliorates Lipopolysaccharide-Induced Intestinal Inflammation, Yi Shan, Xiaoling Liu, Shumei Wang

Journal of Food Science and Biotechnology

[Objective ] This study aimed to investigate the effects of goat milk formula powder on lipopolysaccharide (LPS)-induced intestinal inflammation and barrier impairment in mice.[Method ] Histopathological observation,real-time quantitative PCR,and enzyme-linked immunosorbent assay were used to assess changes in intestinal inflammation levels and barrier function-related indicators in mice following intervention with goat milk formula powder.Additionally,the composition of the gut microbiota was analyzed to elucidate its potential mechanisms of action.[Result ] Goat milk formula powder alleviated intestinal histopathology and increased the number of goblet cells.Compared with the model group,the goat milk formula powder intervention reduced the mass fractions of pro-inflammatory cytokines TNF- …

Design , Expression , And Stability Evaluation Of A Superoxide Dismutase-Catalase Fusion Protein, Zhuo Jiang, Weina Lu, Qi Lin, Zhan Luo, Zhengbin Lyu, Zuoming Nie

Journal of Food Science and Biotechnology

[Objective ] This study aims to design a fusion protein with high activities and high stability of superoxide dismutase (SOD ) and catalase (CAT ).[Method ] Using AcSOD 11 and FeCAT proteins as the research subjects,three fusion proteins of SOD and CAT were designed:AcSOD 11-(GGGGS )*3-FeCAT,FeCAT-(GGGGS )*3-AcSOD 11,and FeCAT- (EAAAK )*3-AcSOD 11,which were named AcSOD 11-G3-FeCAT,FeCAT-G3-AcSOD 11,and FeCAT-E 3-AcSOD 11,respectively.Soluble expression of these three fusion proteins was achieved in Escherichia coli BL21(DE3).The thermal stability and pH stability of the three fusion proteins were then assessed.[Result ] The three fusion proteins showed no significant difference in the specific activity of SOD,while …

Pathways To Better Sleep, Mairead E. Moloney, Emily Slade, Joon Chung, Kory Heier, Daniela C. Moga

Sociology Faculty Publications

Background: Rural Appalachia has some the highest rates of sleep and health disparities in the United States. This study investigates the relationship between social support and insomnia severity in rural Appalachian adults, with specific attention to the potential mediating roles of depression, anxiety, and stress. Methods: Participants from 12 rural Eastern Kentucky counties completed validated measures of insomnia severity, social support, depression, anxiety, and perceived stress. Using R, we calculated descriptive statistics and fit mediation models for depressive symptoms, anxiety symptoms, and stress, with social support as the exposure and insomnia severity as the outcome. Results: Aligning with regional demographics, …

Effects Of Proactive Interference On Adults With Adhd: A Sex-Based Study, Julia Switzer

Honors Theses

ADHD is a widespread phenomenon that affects individuals in a variety of ways. Many individuals exhibit strong proactive interference, in which past memories interfere with the memorization and recall of new information. One of the ways symptoms differ is through the biological sex of individuals, although differences in proactive interference have not been studied in relation to sex. This study hypothesized that women with ADHD are better at resisting proactive interference than males with ADHD. The study involved a digital activity in which a series of colored shapes was shown to participants, who identified whether the previously displayed shapes or …

Table Of Contents

New England Classical Journal

No abstract provided.

Sticker Or No Sticker, That Is The Question: A Test Of Two Competing Hypotheses, Dongdong Yang, Yi Luo, Marylou Naumoff

College of Communication and Media Scholarship and Creative Works

Stickers, as an important nonverbal communication affordance on social media, have been understudied in Western contexts. This study employed an online survey (N = 300) to test two competing hypotheses—the social compensation and withdrawal hypotheses—to examine how personality traits influenced sticker use for emotional expression and self-presentation among U.S. college students. Results demonstrated that when communicating with a new friend on their mobile messenger, participants used stickers more frequently for self-presentation than emotional expression. Moreover, loneliness was positively related to neuroticism and negatively related to agreeableness and extraversion. Neuroticism was negatively related to sticker use for both emotional expression and …

Analyzing Intellectual Alternatives To Student Academic Output ``A Specialized Study Of Academic Design Ideas And Alternatives'', Riyam Rajab Fanjan, Armin Sarkis Khosrof

Journal of King Abdulaziz University: Engineering Sciences

The design idea is the foundation on which the architectural design process. It is the basis for creating a distinguished architectural product that reflects the designer's thoughts, orientations, and way of thinking, whether within the black box or the glass box. Generating and selecting alternatives is one of the most important stages, followed by translating the alternative formally and functionally according to the design methodology followed by the designer and according to the design specifications represented by the type of project and its contextual constraints. In the context of architectural work, the research focuses on defining the design idea, the …

Multi-Criteria Decision-Making For Bid Evaluation And Selection In Water Resource Management Projects, Abdulaziz Alkabaa, Salah Omar Ammari, Abdul Z. Hameed

Journal of King Abdulaziz University: Engineering Sciences

We propose an enhanced multi-criteria decision-making (MCDM) framework using the Analytic Hierarchy Process (AHP) tailored for bid evaluation in water resource management projects. This approach addresses the persistent challenges of transparency, inconsistency, and technical-financial weighting observed in competitive bidding systems. By incorporating structured criteria across qualitative and quantitative dimensions, our model offers a more systematic, equitable, and operationally robust alternative to traditional evaluation practices. Case study applications demonstrate the framework's ability to yield clear differentiation among bids, improve decision traceability, and support procurement efficiency. These findings offer practical implications for policymakers and project stakeholders seeking to modernize bidding practices within …

Leveraging Deep Learning Models To Predict The Impact Of Project Changes On Timelines, Costs, And Quality For Enhanced Project Management, Ahmed Alkhard

Journal of King Abdulaziz University: Engineering Sciences

Managing projects in the modern world seems to be growing in dimness as it incorporates risks from multiple advancements which cut across technology, interrelationships between regions and developing societal expectations. Typical project management systems do not have the necessary accuracy or flexibility to include the possible impact of change in key components, such as scope change, resource changes, and external factors changes on the end values of performance metrics such as time, cost and quality. Such constraints are overcome in this work by implementing Deep Learning models such as FNN, LSTM networks, Attention Mechanisms or Ensemble models as the predictive …

Technical And Economic Study For Applying Solar Energy Systems To Government Buildings, Saeed Alghamdi

Journal of King Abdulaziz University: Engineering Sciences

Abstract: This paper presents a comprehensive feasibility study for integrating solar energy systems into three government buildings in the Kingdom of Saudi Arabia and connecting them to the public electricity grid. The study evaluates the project's economic viability by analyzing three years of electricity consumption data from these buildings. This analysis highlights the potential cost savings and environmental benefits of adopting solar power. Key factors such as average solar energy production, site-specific geographical conditions, and seasonal variations in sunlight were considered. The study utilized PVsyst software to simulate and optimize the solar photovoltaic (PV) systems, determining the number of solar …

Design And Optimization Of A Geothermal Thermoelectric Generator System (Gteg) In Saudi Arabia, Hassan Fagehi

Journal of King Abdulaziz University: Engineering Sciences

The demand for renewable energy is growing rapidly, driven by climate change and the need for sustainable solutions. This study focuses on designing and optimizing a geothermal thermoelectric generator (GTEG) system in Saudi Arabia, leveraging the country's geothermal potential. The optimization process investigated key parameters such as substrate materials, thermoelectric leg length, and dimensionless thermal and electrical conductance. The results reveal that using AlN as a substrate material, combined with a reduced leg length of 0.1 mm, significantly enhances power output, achieving 8.5 W per module. Dimensionless analysis further identified optimal dimensionless thermal conductance (N_k = 0.291) and dimensionless …

Techno-Economic Feasibility Study Of Rooftop Photovoltaic System For Soba Industrial Area, Khartoum State, Sudan, Ibrahim Ahmed Ibrahim Ali

Journal of King Abdulaziz University: Engineering Sciences

This study presents a detailed techno-economic assessment of a rooftop grid-connected photovoltaic system for Soba Industrial Area in Khartoum State, Sudan. Utilizing advanced modeling tools, namely the System Advisor Model and RETScreen Expert, critical technical parameters such as capacity factor, yield factor, and performance ratio, alongside key economic indicators including levelized cost of energy, payback period, and net present value are evaluated. The investigation also explores optimal panel orientation and conducts a sensitivity analysis of a two-axis tracking system, revealing its' potential for enhanced energy production. Findings indicate that the optimal tilt angle for the photovoltaic systems is 19 degrees, …

Impact Of Staff Education To Clinical Documentation Integrity Team, Leyna Belcher

Walden Dissertations and Doctoral Studies

The doctoral project investigates the impact of education on Clinical Documentation Integrity (CDI) nurses in enhancing the accuracy and quality of clinical documentation within healthcare organizations. Clinical documentation plays a crucial role in accurately reflecting patient care and is essential for capturing proper diagnoses, coding, and reimbursement. In contrast, inaccurate or incomplete documentation can lead to misdiagnoses, poor patient outcomes, and financial deficits. Due to frequent updates in clinical guidelines and coding standards, CDI professionals require continuous, specialized training to stay informed with ever-changing medical terminology, disease processes, and coding regulations. By enhancing the CDI education, the aim is to …

Transition-To-Practice Program For Aprn Msn Graduates, Jennifer Nneoma Nwosu

Walden Dissertations and Doctoral Studies

The transition from graduate education to clinical practice marks a pivotal point in the professional journey of advanced practice registered nurses (APRNs). Despite rigorous preparation, many APRN MSN graduates struggle to adapt to the complex expectations of autonomous practice. The lack of structured mentorship, inconsistent orientation processes, and unclear performance expectations contribute to high stress, role confusion, and early turnover. This Doctor of Nursing Practice Executive Leadership project addressed this critical issue by evaluating whether an interprofessional team could achieve consensus on developing a best practice program to guide APRN MSN graduates’ transition to independent clinical practice. This initiative was …

Staff Education To Improve Knowledge Of Probiotic Use And Benefits For Best Patient Outcomes, Rebecca M. Hoover

Walden Dissertations and Doctoral Studies

Abstract The staff education project to improve knowledge of probiotic use and benefits with antibiotic use, has shown to improve patient recovery and outcome. The post-implementation impact of the project is increased awareness of probiotic use and their benefits to prevent Antibiotic. Associated Diarrhea at the project site organization. I identified no limitations in the project. Staff education can be used worldwide to prevent digestive diseases with the use of probiotics supplements or probiotic food. Probiotics use is to improve patient outcomes by maintaining gut microbiome and digestive health. The evidence-based practice solution of a staff education on probiotic use …

Windkessel Parameter Estimation For Cardiovascular Feature Identification In Photoplethysmography Data, Calvin Boyce

Undergraduate Honors Theses

Features of cardiovascular health such as blood pressure, cardiac output, arterial compliance, and blood viscosity are important in evaluating heart health and disease risk, but are currently largely measured invasively and therefore only in critical settings. Here we explore the potential for Windkessel models to extract cardiovascular features from photoplethysmography (PPG) data in an attempt to evaluate heart health non-invasively. We show the capacity of a constrained Newton's method optimization scheme to estimate parameters and explore the tractability of the resulting parameters. While Newton's method is able to produce parameters that closely approximate PPG data, we found that using a …

Listening To Life In A Noisy World: The Pitfalls And Promise Of Urban Acoustic Ecology, Leah O'Barr

Undergraduate Honors Theses

This thesis examines the application of soundscape ecology principles to urban settings. Soundscape ecology is the study of the entire sonic makeup of a community, composed of biophony (biological sound), geophony (environmental sound), and anthrophony (human-generated sound). By examining the changes in and qualities of the soundscape, researchers can gain information about the biological makeup and ecological quality of an area, and the temporal and spatial distribution of resident species. Recent technological advances in recording equipment and machine learning methods are making soundscape ecology an increasingly relevant and practical tool.

Applying soundscape ecology methods to urban ecosystems introduces unique challenges, …

Introduction - The Crown, Vol. 2, The Crown

The Crown: Syracuse Honors Research Journal

No abstract provided.