Digital Commons Network^™

Krasg12d Mutation Promotes Pancreatic Tumorigenesis By Suppressing Sirtuin Three Via The Guanine Nucleotide Exchange Factor Rcc1, Taoyi Mai, Mengwen Wang, Ya Qiu, Wenhua Lu, Hongyu Wu, Shuna Chen, Paul J Chiao, Peng Huang

Faculty, Staff and Student Publications

KRASG12D mutation is a prevalent gain-of-function mutation that drives pancreatic cancer tumorigenesis, but the underlying mechanisms that promote KRAS-induced cell proliferation and tumor formation remain elusive. To uncover the molecular pathways that facilitate KRASG12D-driven malignant transformation, we measured the transcriptomic alterations at various time points after induction of KRASG12D expression in human pancreatic normal epithelial cells. KEGG pathway enrichment of the differentially expressed genes (DEGs) showed that the major DEGs were located in pathways that regulate nicotinate/nicotinamide metabolism, TNF signaling, and microRNAs associated with cancer. Among these molecular alterations, the NAD-dependent deacetylase gene SIRT3 was significantly down-regulated by KRASG12D. Conversely, …

Despite Successful Lawsuits And Investigations, Kensington Grocery Stores Still Deny Workers Legal Wages, Tareq Saghie

Capstones

This article looks at three grocery stores in Kensington, Brooklyn that continue to pay immigrant workers below legal wages despite courts and the Department of Labor penalizing them for it repeatedly. The reporting speaks to the ineffectiveness of the law at deterring labor violations, the commonality of wage theft in New York's grocery stores, and the impacts it has on workers.

https://medium.com/@tareqsaghienyc/despite-successful-lawsuits-and-investigations-kensington-grocery-stores-still-deny-workers-legal-a332c980a1cb

What’S That Smell? It’S Climate Change!, Perry Gregory

Capstones

Climate change is going to make New York City smell worse. Reporter Perry Gregory breaks down the process of olfaction and explains how heat affects what we smell. The piece features a collage of voices of New Yorkers describing the current smell profile of the city. The report features insight from several Atmospheric Scientists into why New York City is getting hotter and more humid, and how those climate changes will make the existing smells of the city stronger, and worse. The most economically vulnerable New Yorkers, who cannot afford air conditioning to buffer them from heat, will be the …

San Mateo County’S Digital Jail Mail Sparks Reckoning Over Private Data, Juan A. Lasso

Capstones

This capstone examines privacy and data risks embedded in digital communication systems used in U.S. correctional facilities. As private vendors introduce tablets, kiosks, and mail digitization services, these technologies enable widespread surveillance and data collection of incarcerated people and their loved ones. The project explores how these systems track and analyze digital footprints in ways that challenge established legal and ethical expectations around privacy. It documents the personal impact on loved ones of people currently or formerly incarcerated in San Mateo County. The reporting centers on the California county jail where a civil rights lawsuit is pending over the mail …

A Halloween Decoration’S Scary Implications For Real Bats, Coralie Carlson

Capstones

This investigative article examines the online illegal trade of taxidermied bats and how the sales are threatening one particularly showy species: the painted woolly bat.

My OSINT research shows where the bats are still sold – from Amazon to independent websites offering bulk orders – and tracks the sellers and buyers, while weaving in the scientific and cultural history this little-known colorful bat and the conservationists’ race against time to protect them.

The very existence of the painted woolly bat is threatened by Americans who want to display the dead bats in their homes as spooky decorations. Researchers (including a …

Halt Under Threat Why Legislators Must Demand Compliance Before Change A Playbook For Action, Vanda Seward

Capstones

This playbook examines the implementation of New York State’s Humane Alternatives to Long-Term Solitary Confinement (HALT) Act and presents evidence demonstrating that the law has not been fully or consistently enforced by the New York State Department of Corrections and Community Supervision (NYSDOCCS). Drawing on findings from the New York State Inspector General, the Correctional Association of New York, the Justice Center, court rulings, and community testimony, the analysis documents persistent violations, including excessive and illegal use of solitary confinement, inadequate documentation, failures to protect vulnerable populations, and insufficient accountability for staff misconduct. The playbook critically evaluates the recommendations of …

Security Blanket: An Idea Of "Home" Across The Housing Spectrum, Willa D. Odefey

Capstones

Security Blanket: an idea of "home" across the housing spectrum addresses the logistical and emotional gaps left by policy-makers who prescribe a one-size-fits-all approach of housing to New York City’s houseless crisis. Independent living can be a major adjustment for people who have never lived on their own (eg. lived with parents, were formerly incarcerated, were in long-term hospital care), and shelters do not adequately prepare residents for the life-building steps after move-out. I asked New Yorkers experiencing homelessness where they are now, what home means to them, and what it would or has taken to ground themselves as they …

New Yorkers Training, Mobilizing To Protect Immigrants As Federal Crackdown Intensifies, Cristina Ledra, Andrew Serulneck

Capstones

As the Trump administration escalates deportation efforts nationwide, New York City is bracing for increased enforcement, with advocates warning that fear of deportation raids is already reshaping daily life for immigrant communities. New York protesters have not yet faced the most severe federal charges following high-profile confrontations, as protesters have in other states around the country. And the federal cases are largely falling apart and not resulting in trials or convictions. Despite the legal threat, some advocates see the moment as galvanizing.

https://docs.google.com/document/d/e/2PACX-1vQrUcmMi4XgxnkjMV-h58Cp3RTxfmIEt95H79uo7CDFlYD5lo59QylxoWozHJhBhlxHCzA98XHnwX7-/pub

The Box Office Keeps Disappointing. Indie Movie Theaters Keep Selling Tickets Anyway., Ella Feldman

Capstones

It’s been a tough five years at the box office, which has yet to recover from the impact of COVID-19 and the explosion of streaming options. But across the country, independent movie theaters have managed to buck the trend, according to industry data and interviews with theater operators. This feature story explores how indie cinemas have staged their post-pandemic comebacks.

How Armenia And Azerbaijan Are Lobbying For Influence In D.C., Gibran C. Boyce, Dawn Kikel

Capstones

In the wake of President Trump taking office, foreign government agencies and U.S.-based non-profits serving Armenian and Azerbaijani interests have been hiring lobbyists in Washington, D.C. as part of their concerted efforts to curry favor, gain influence, and seek policy changes that would benefit the rival post-Soviet nations.

Fake News Y Redes Sociales: Cómo El Algoritmo En Torno A La Migración Afecta La Salud Mental, Maria F. Alarcon

Capstones

Las redes sociales son la principal fuente de información para migrantes latinos en Estados Unidos, pero también son un terreno fértil para fake-news que afectan la salud mental y desinforman.

Defiance Through Noise, Tyler Paz

Capstones

Defiance Through Noise analyzes the eviction of Punk HQ from 39 Eldridge Street within the broader history of punk-led, DIY, and squatted spaces in New York City. Using court records, historical context, and firsthand accounts from organizers, former nonprofit workers, and participants, the project examines Punk HQ as both a community space for marginalized youth and a continuation of Lower East Side squatting traditions from the 1970s and 1980s. The reporting situates its closure within intersecting forces of government disinvestment, housing policy, post-pandemic economic pressures, and the nonprofit industrial complex that have contributed to the decline of autonomous cultural spaces. …

Beyond The Model Minority: South Asian New Yorkers Confront Poverty, Mizuki Uchiyama

Capstones

This capstone project examines poverty among South Asian immigrants in New York City, challenging the “model minority” myth that portrays Asian Americans as uniformly successful. Through a reported NY1 television news package and accompanying written narrative, the project highlights how language barriers, economic insecurity and limited access to public benefits shape daily life for many immigrant families in Queens.

Reporting from the South Asian Council for Social Services (SACSS) in Flushing, the story connects individual experiences in workforce and sewing programs to broader data showing that Asian New Yorkers experience poverty at rates comparable to Black and Latino residents, with …

Building Another World, Christopher Edwards

Capstones

"Another World" is a mutual aid hub in Crown Heights, Brooklyn. The space was opened in June 2025 and is ran by the Crown Heights Care Collective, a mutual aid network started in 2022. Another World hosts free events surrounding political education and provides basic needs like food and clothing to residents of the area. In just a few months, the group has made inroads in a diverse community altered by gentrification.

The Remnants Of Nyc's Asylum Shelters, Charles Finnerty

Capstones

Since the spring of 2022, over 200,000 migrants and asylum seekers have arrived in New York City. For three years, the Eric Adams administration’s response shifted constantly, from welcoming new arrivals with open arms, to clashing with the Biden White House over federal support, to collaborating with the Trump administration’s mass deportation regime

Behind all these headlines and political fights, the city’s outer borough neighborhoods have absorbed new arrivals in school systems, gig work economies and over 150 shelters. Local government and corporate news media have largely failed to inform the public about the city's shelter program, allowing confusion and …

2025 Fall Commencement, Harding University

Commencement Programs

Program for the Harding University Commencement on December 13. 
Commencement Speaker: Dr. Susan Kehl

Pen And Punishment: Revenge And Role Reversal In Edith Wharton’S World. A Rewriting Of Gender Roles And The Subversion Of Patriarchy., Shelly Ann Justin

Arts & Sciences Graduate Student Theses and Dissertations

ABSTRACT OF THE DISSERTATION Pen and Punishment: Revenge and Role Reversal in Edith Wharton’s World. A Rewriting of Gender Roles and the Subversion of Patriarchy. by Shelly Ann Justin An unlikely feminist writer sometimes becomes one of the greatest advocates for the feminine movement, and that is exactly what American novelist, Edith Wharton (1862-1937) has done for over 120 years through her essays, short stories, and more specifically, her novels. She is best known for her vivid novels that explore the complexities of American society, especially the upper class which examines the constraints and social expectations of New York’s upper …

Efficacy Of Oil And Gas Production Site Remediation In U.S. Arid/Semi-Arid Regions, Skye Ontiveros

Architecture and Planning ETDs

Oil and gas production (OGP) is expanding, paralleled by its polluting leaks and spills (LS), and outpaced by its waste. This raises the question: Does remediation of LS occur effectively when needed to protect the environment and public, particularly in major producing regions like arid/semi-arid regions (ASAR), which account for approximately 72% of US oil and 42% of gas production? To answer, a review of the eight largest national remedial laws, sourced from the Code of Federal Regulations (CFR), identified 14 OGP exemptions for remedial determinants (RDs): factors affecting remedial frequency and efficacy (e.g. LS monitoring and chemical disclosure). An …

How To Talk To A Seahorse: Communication In Transmasculine Gestational Experiences As Told Through Narrative, Emerson Armstrong

Communication ETDs

Transmasculine experiences before, during, and after pregnancy were evaluated using focus groups and autoethnographic research. As transgender people are more likely to experience inequality in healthcare encounters, this project aims to shed light on, and counter sensationalized accounts of male pregnancy, as transmasculine gestational individuals sought normalization in their experiences of pregnancy. Seven focus groups consisted of 90 minute sessions, with a total of 15 participants. Transcripts were analyzed using a trans narrative approach to find a greater understanding about identity construction, challenges, and changes around trans pregnancy. Asking about communities and healthcare experiences worked to create a complete picture …

From Energy Abundance To Blackouts: Political Explanations For Ecuador’S 2024 Electricity Crisis, Selene V. E. Diaz Martinez

Political Science ETDs

Ecuador’s growing reliance on hydropower has positioned it as a regional leader in renewable energy development. However, recent droughts have exposed the vulnerability of this energy model in the face of climate change. In 2024, widespread blackouts underscored the risks of overdependence on hydroelectricity in the country. The media suggested that the cause of the blackouts was due to an abnormal drought that year. However, climate change alone cannot explain the lack of use of other generation sources to meet demand. suggesting that a review of political choices could provide insight into the sector's failure. This research examines the political …

Dense Temporary Array Investigation Of Jemez Uplift Seismicity, Jillian D. Podmore

Earth and Planetary Sciences ETDs

A protracted multi-stage tectonic and magmatic evolution combined with low regional crustal strain rates make it challenging to characterize active structure that may host earthquakes in the Jemez Mountains of New Mexico. Here, we leverage temporary 1-month deployments of nodal seismometers to gain new insights into seismicity of the Jemez Mountains, which only have continuous seismic monitoring on their eastern flank as a result of the Los Alamos Seismic Network. Our catalog is built using 4 steps: phase picking in continuous seismic data, association of picks to detect unique events, event magnitude estimation, and absolute hypocenter estimation. We detect and …

Guillaume Dustan's Ethico-Politics Of The Body, Noah Mertz

Foreign Languages & Literatures ETDs

In this MA Thesis, I lay out a synthetic overview of polemical French writer Guillaume Dustan's (1965-2005) political philosophy. He is criticized first as irresponsible and dangerous for his defense of barebacking (sex without condoms) in the midst of the AIDS epidemic, and then, after his death, as a neoliberal/anarcho-capitalist for his focus on individual liberty. My overview touches on Dustan's Freudian belief that repression is the root of all social ills, his functional ethics of self-responsibility, the revaluation of heteronormative Judeo-Christian morality towards 'virtusex,' and his social contract that minimizes repression. Dustan’s goal is for you to autonomously subjectify …

Physical Education Through The Lens Of A Transgender Individual, Allison L. Graham

Health, Exercise, and Sports Sciences ETDs

Transgender students face unique challenges in K–12 physical education (PE) that other groups of students do not experience. The purpose of this qualitative study was to explore the life history of a transgender woman, Evergreen, with a focus on her experiences in PE throughout K-12 school. This study was guided by Queer Theory (Jagose, 1996) and Atkinson’s (1998) life history methodology, data was collected through nine semi-structured interviews and participant-selected artifacts. Data was analyzed using Merriam and Tisdell’s (2016) coding procedures to identify themes. Findings revealed distinct experiences across four areas: (1) Elementary School PE—positive memories centered on play …

Predicting The Unpredictable: Advancing Risk Management In Fitness Centers Through Data Science-Driven Judicial Outcome Modeling, Hongyoung Kim

Health, Exercise, and Sports Sciences ETDs

This study developed a prediction model of judicial outcomes in fitness exercise-related injury lawsuits to identify key factors influencing fitness centers’ success in litigation. Using 209 U.S. court cases from Westlaw, Phase One employed text mining and content analysis to identify legal variables. Phase Two applied descriptive statistics and multiple logistic regression to evaluate the combined influence of these variables on judicial outcomes. For the multiple logistic regression analysis, the sample size was reduced to 184 cases after excluding 25 remanded cases.

Results showed that victim behavior, hazardous facility conditions, and enforceable waivers or exculpatory clause defenses significantly predicted judicial …

Modeling Mineral Redistribution In Biological Tissue Using Apple As An In Vitro Analogue, Daler Djuraev, Ali Algemsh, Halima Alazeb, Zeenia Ahmed

Publications and Research

This project aims to model mineral (ion) redistribution that occurs in human soft tissue after injury or mechanical/thermal stress. Because direct, repeatable in vivo measurements are difficult, we use apples as an in vitro analogue: their mineral content is relatively uniform and the tissue can be cut, dried, and repeatedly imaged under controlled conditions. Using X-ray imaging, we tracked how minerals in apple tissue move toward damaged regions immediately after cutting, and how subsequent drying at room temperature drives a redistribution toward the central core. We also observed that biological degradation (decay) alters mineral density over time, indicating that even …

Book Review: Academic Coaching: Coaching College Students For Success, Corinne Bishop

Journal of Graduate Librarianship

Book review: Howlett, M. A., & Rademacher, K. (2023). Academic coaching: Coaching college students for success. Routledge. 196 pp. ISBN: 9781032272214 (paperback), 9781032265711 (hardcover), 9781003291879 (ebook).

Pembuktian Sederhana Dalam Proses Kepailitan Terhadap Perusahaan Pengembang Pasca Surat Edaran Mahkamah Agung Nomor 3 Tahun 2023, Maya Iswandi

Jurnal Hukum & Pembangunan

Abstract

After the issuance of Sema No. 3/2023, there were various pros and cons to its implementation. This is because the sema has limited and in quotes has protected development companies from bankruptcy proceedings. Sema No. 3/2023 provides immunity to development companies from bankruptcy because they are deemed not to meet the simple proof that must be met in the bankruptcy process. This provision seems to deny the judicial system that should determine the evidence in a case. This certainly causes degradation of legal certainty and consumer protection. Therefore, this research will discuss simple proof in development companies after the …

Prevention Of Suicide As Perceived By Educated Adults In Ondo Metropolis, Ondo State, Nigeria, Margaret Kehinde Soetan

Buletin Konseling Inovatif

This study investigated prevention of suicide as perceived by educated adults in Ondo metropolis, Ondo State, Nigeria. Descriptive survey research design was adopted for this study. Population of the study consisted of all educated adults in Ondo metropolis, Ondo State. The sample comprised two hundred (200) educated adults randomly selected from the metropolis. Structured questionnaire was used as instrument to collect data for the study. Data collected was analysed using mean, ranking, t-test and analysis of variance (ANOVA). The results revealed the perception of prevention of suicide as giving people hope for a better life after current problems are resolved, …

Needs Analysis: Ar As An Innovative Learning Media Solution For Elementary School Students, Rosfaniarti Rosfaniarti, Makmum Raharjo, Meilinda Meilinda

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aims to identify the need for the development of Augmented Reality (AR)-based learning media as an innovative solution in elementary school learning. The needs analysis method was conducted using a mixed methods approach through questionnaires and interviews with 103 students and 5 teachers. The data were analyzed descriptively and quantitatively to obtain a comprehensive picture of instructional needs. The results showed that student needs were in the high category, with a percentage of 80.64%-85.30%. The socio-cultural aspect was the highest need (85.30%), followed by the pedagogical and technical aspects, while the cognitive aspect had the lowest value (80.64%). …

Improvising Across Abilities: Pauline Oliveros And The Adaptive Use Musical Instrument [Book Review], Maria A. Souliotis

Disability in LIS (DisLIS)

This book reviews how the AUMI movement has evolved in the years since its inception, with the people involved in it most closely detailing its impact on music education and disability activism. Narratives, case studies, and personal reflections highlight Oliveros’ philosophical and realized contributions to the AUMI movement, which until this book’s publication has received little attention.