Digital Commons Network^™

Buffer Vs. Swabs: Efficacy Of Carrier Nucleic Acids In Robotic Extractions, Shawn Cecil

Honors Projects

This study compared the efficiency of two carrier nucleic acid methods, specifically using salmon sperm DNA (spDNA), in robotic solid-phase extractions of cotton swab samples. Robotic extractions reduce processing time and workload but result in substantially lower DNA recovery than manual organic extraction. This research tested 10 µg of spDNA being added to the lysis buffer or pre-treating the swabs with it before DNA was added. Both methods showed a significant increase in recovery compared to extractions with no carrier. In the buffer extractions, recovery ranged from 69.4% to 117.5% and the swabs being pre-treated ranged from 84.2% to 125.8% …

Transforming Shrm; Applying The Kotter Method To Niu Shrm, Hunter J. Egelhoff

Honors Capstones

This capstone project examines how Northern Illinois University’s Society for Human Resource Management transformed its organizational structure and programming to better prepare students for today’s competitive job market. With workforce demands shifting toward practical experience, employer expectations have exceeded what traditional classroom education alone provides, creating a growing gap between student readiness and career requirements. To address this disconnect, NIU SHRM applied Kotter’s Eight-Step Change Model to restructure leadership roles, integrate experience-based learning, and enhance student engagement through workshops, partnerships, and leadership development opportunities. This change initiative resulted in increased visibility, participation, and measurable short-term successes that now serve as …

Housing Burden And Insurance Expenditures, Melanie M. Lytell

Honors Capstones

Housing costs shape the way families spend on protection and security. This study looks at how the share of income devoted to housing, the housing burden, influences household spending on four types of insurance: vehicle, life, personal, and health. Using data from nearly 92,000 households and regression models that account for state differences, I find that even small increases in housing burden shift insurance choices in meaningful ways. A one‑percentage‑point rise in housing burden is linked to a 2.1% increase in vehicle insurance spending and a 0.5% increase in life insurance, but a 0.7% decrease in personal insurance and a …

The Importance Of A Pressure Injury Prevention Program In Acute Hospital Settings, Sarah Orial

Student Scholarly Projects

Practice Problem: The identified practice problem for this project was the lack of a standardized pressure injury prevention program in a 350-bed acute care hospital. The lack of a standard program could be leading to increased hospital-acquired pressure injuries. PICOT: In adult inpatients in a medical/surgical unit (P), does the implementation of a standard unit-based pressure injury prevention program (I) compared to the current practice (C) increase the percentage of nursing skin risk assessment documentation (O) over a 10-week period (T)?

Evidence: The literature supports the development of standard pressure injury prevention programs and continuing education to …

Social Media Classifications: The Impact On Sports Content Consumption, Katie Schmitz

Honors Projects

This study examines how classifications of social media content influence consumer engagement within the context of collegiate athletics. Focusing on the Bowling Green State University football team's official Instagram account, the research analyzes posts from the 2025 football season by exploring how content type, post format, and engagement metrics relate to visibility and reach. Guided by theoretical frameworks including vividness, interactivity, and the Theory of Planned Behavior, the study employs a quantitative analysis using publicly available engagement metrics. This research contributes to growing literature on sport and social media by addressing a gap in classification-based engagement analysis. Findings provide a …

Investigating Factors That Affect Total Ige Antibody Levels Of A Canine Population In Louisville, Ky, Iris N. Gillespie

Undergraduate Theses

Canine atopic dermatitis (CAD) is a genetically predisposed condition that causes inflammatory and pruritic (itchy) skin reactions in response to environmental and food allergens. The main purpose of this study is to determine if there is a correlation between pollen counts and total canine IgE antibody levels of dogs living in Louisville, KY. Additionally, data is analyzed to look for trends documented in previous studies related to the impacts of sex, age, and allergic symptoms on total IgE count. In collaboration with the Downtown Animal Hospital, blood samples were drawn from 16 dogs at one point in February (when pollen …

Optimizing Xo Throughput At Imerys, Derek Beasley, Brennan Chandler, Baris Erarslan, Cynthia Grogin

Senior Design Project For Engineers

This project is conducted in collaboration with Imerys to optimize the performance of the VSI (Vertical Shaft Impactor) system at their Plant 4 facility, focusing on improving the production of XO, a fine material used in products such as textured coatings, acid neutralization, and water filtration systems. The VSI operates continuously, producing several materials at the Marble Hill, Georgia location, including #1 Chip, #2 Chip, OZ, XO, Z, and 30–50. The main focus of this project is to increase the throughput of XO, as it requires both throughput improvement and product quality consistency to meet growing market demand. Imerys’ quality …

Endothelial-Derived Extracellular Vesicles During Exercise In Copd Patients, Samuel C Okpechi, Dorota Wyczechowska, Bennett Deboisblanc, Jessica L Johnson, Mohamed A Ghonim, Natalie Bauer, Hamid A Boulares, Matthew R Lammi

School of Medicine Faculty Publications

Introduction: There are no treatments directly targeting the pulmonary vasculature in chronic obstructive pulmonary disease (COPD), and further characterization of the underlying endothelial cell (EC) abnormalities could be helpful in drug development. Methods: We investigated the influence of exercise and the prostacyclin analog iloprost on extracellular vesicles derived from ECs (eEVs) in 15 moderate–severe COPD patients who were enrolled in a randomized, placebo-controlled crossover trial of iloprost. Results: Active smokers had a profile consistent with inflammatory-derived EVs, while exacerbation-prone COPD subjects had a profile consistent with apoptosis-derived eEVs. There were no significant effects of iloprost on eEV levels. However, there …

Ethical Review Of Discipline-Based Education Research: Ensuring Fair Treatment For All, E. Elias Johnson

Undergraduate Honors Theses

As universities grapple with funding cuts and heightened social and political pressure, the emerging field of Discipline-Based Education Research (DBER) aims to improve student learning outcomes through experimental instruction. While using instruction as an experiment, with hypotheses and experimental tests, DBER research may affect student learning and experience in unintended ways for students involved in these classes. To address this concern, I impose ethical frameworks, namely contractualism, to better understand how the values of each stakeholder, students enrolled in experimental courses and researchers using these courses to test hypotheses, interact. I also identify potential misalignments. Following a contractual ethical framework, …

Early Peripheral Blood Gene Expression Predicts 90-Day Outcomes Following Subarachnoid Hemorrhage, Bodie Knepp, Garreck H Lenz, Frank R Sharp, Fernando Rodriguez, Huimahn Alex Choi, Aaron M Gusdon, Glen Jickling, Lara L Zimmermann, Ryan Martin, Jeffrey Vitt, Ben Waldau, Brandon J Cord, Alan Yee, Kwan Ng, Nerissa U Ko, Heather Hull, Bradley P Ander, Boryana Stamova

Faculty, Staff and Student Publications

BACKGROUND: Previous clinical, radiological and machine learning studies have predicted 90-day outcomes following subarachnoid hemorrhage (SAH). The present study was designed to determine whether early changes in mRNA expression of immune, clotting and other genes expressed in peripheral blood can predict patient outcomes at 90 days after SAH and possibly provide insights into the molecular factors that promote good versus poor outcomes.

METHODS: Peripheral blood was drawn after SAH and from vascular risk factor controls (VRFC) and RNAseq performed to measure mRNA expression. A mixed effects regression model identified potential predictors and machine learning algorithms derived the best predictors of …

Bayesian Learning To Reduce Cardiac Risk Of Patients With Locally Advanced Non-Small Cell Lung Cancer Based On Personalized Radiation Therapy Prescription, Ruitao Lin, Mei Chen, Xiaodong Zhang, Tianlin Xu, Ting Xu, Rachel C Maguire, Kelsey L Corrigan, Efstratios Koutroumpakis, Joe Y Chang, Steven H Lin, Aileen B Chen, Quynh-Nhu Nguyen, Saumil J Gandhi, Matthew S Ning, Julianna Bronk, Stephen Chun, Ali Ajdari, Joshua S Niedzielski, Jinzhong Yang, Xinru Chen, Tinsu Pan, Qing H Meng, Anne S Tsao, Anita Deswal, Radhe Mohan, Zhongxing Liao

Faculty, Staff and Student Publications

Purpose: Radiation-induced heart damage is a significant concern in the treatment of non-small cell lung cancer (NSCLC) that can have debilitating or life-threatening consequences. Current strategies focus on minimizing heart exposure, but individual susceptibility varies. Existing evidence also suggests that a uniform "one-size-fits-all" dosimetric constraint for the heart may not be optimal for all patients.

Methods and materials: We developed a prospective study using Bayesian continuous learning and adaptation to develop a framework for personalized adaptive radiation treatment (PART) to reduce cardiovascular adverse events among patients with locally advanced NSCLC. The trial includes a Bayesian personalized risk prediction model to …

A Review Of Recent And Developing Studies Regarding Percutaneous Coronary Intervention (Pci): A Narrative Review, Bisher Alsabbagh, Azeez Shala, Joshua Rupert, Abdallah Elsayed

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

This comprehensive literature review synthesizes the most recent evidence and evolving clinical guidelines concerning percutaneous coronary intervention (PCI) from 2015 to 2025. The study integrates findings from 42 peer-reviewed trials, meta-analyses, registries, and international guideline statements issued by the American College of Cardiology/American Heart Association (ACC/AHA), European Society of Cardiology (ESC), and related societies. Results reveal a decade-long evolution in PCI practice marked by a shift from anatomy-driven to physiology and imaging-guided decision-making, supported by tools such as fractional flow reserve (FFR), instantaneous wave-free ratio (iFR), intravascular ultrasound (IVUS), and optical coherence tomography (OCT). Modern guidelines emphasize individualized, team-based revascularization …

Improving Communication To Enhance Health Literacy And Self-Management Of Heart Failure: Protocol For A Multimethod Study, Neda Karimi, Francesco De Toni, Walter Abhayaratna, Blake Askelin, Philip Currie, Karol Edge, Christopher Etherton-Beer, Elizabeth Fewster, Liza Goncharov, Nisha Jijo, Susy Macqueen, Nilufeur Mckay, Suzanne Raine, Amineh Rashidi, Christopher Rouen, Rosemary Saunders, Peter Schulz, Rhea Tecson, Diana Slade

Research outputs 2022 to 2026

Introduction Self-care plays a pivotal role in the management of heart failure (HF). Health literacy and empowerment are considered the prerequisites of effective self-care. This project aims to improve self-management in people with HF by describing, analysing and enhancing the communication practices of clinicians and patients to support people with HF to increase their health literacy skills and participate in shared decision-making. Methods and analysis A multimethod research design incorporating an interview component, a concurrent mixed-methods component and a pilot intervention study is used. The study is currently being conducted at two Australian hospitals in metropolitan areas (one public and …

Anticonvulsant Activity Of Simvastatin On Experimentally Induced Epileptic Seizures In Mice, Uday Abdul-Reda Hussein, Nargis Amer Nayef, Baneen Adel Abdul-Hussein, Tamara Hassan Mawazi, Zahraa Kadhim Hussein, Noor Alhuda Ali Saadon, Zainab Mohammed Abd, Fatima Mohammed Alwan, Huda Bassim Latif, Hassanein Mohammed , Razak, Mohammed Rida Majeed, Mohammed Abdul-Elah Abdul-Hamid

Al-Ameed Journal for Medical Research and Health Sciences

Background: Epilepsy is a common neurological disorder characterized by recurrent seizures. Simvastatin was recognized as a new candidate that exhibits a variety of neuroprotective effects, including antioxidant and anti-inflammatory effects that have the ability to inhibit neuronal hyperexcitability and seizure susceptibility.

Aim: The purpose of this study is to assess the possible anticonvulsant action of simvastatin in the mouse seizure model.

Material and Methods: The eighteen adult albino mice (25–30 g) were allotted randomly to three groups (n = 6). Thirty minutes before the induction of convulsion, the groups received different intraperitoneal pretreatments: Group 1: Distilled water (0.1 ml), Group …

Ai Literacy For Nurse Leaders: Advancing Innovation And Transforming Care, Carolyn S. Harmon

Biennial Convention (CONV)

With the rapid integration of artificial intelligence (AI) in healthcare, it is imperative for nurse leaders to develop AI literacy to effectively lead and manage their teams. This presentation explores the significance of AI literacy for nurse leaders, focusing on the benefits of understanding AI technologies and their applications in nursing practice. By equipping nurse leaders with the knowledge and aptitudes to navigate AI systems, healthcare organizations can advance clinical decision-making, streamline administrative workflows, and achieve transformative improvements in care delivery.

The purpose of this presentation is to highlight the critical role of AI literacy in nursing leadership and to …

Economics Of The Olympics: Impact Of Bidding For And Hosting The Olympic Games On International Openness, Adalynn Cherry

Pennsylvania Economic Review

This study investigates how hosting and unsuccessfully bidding to host the Olympic Games impacts total international trade and influences a country’s openness. This relationship is analyzed using the gravity model of trade to perform a regression analysis of total trade levels from 2000 to 2018. The results of this study did not support the idea that hosting the Olympic Games impacts total trade; although, they did show a strong and permanent positive relationship between unsuccessfully bidding to host the Olympic Games and total international trade. These findings highlight the benefits of the Olympic bidding and candidature process as a policy …

Measuring Levels Of Ultrashort-Chain Per- And Polyfluoroalkyl Substances In Blood Collection Tubes, Alina M. Dziembowski

Discovery Undergraduate Interdisciplinary Research Internship

Per- and polyfluoroalkyl substances (PFAS) are highly persistent synthetic chemicals that are now ubiquitous in the environment. Due to PFAS stability leading to its environmental persistence, there is concern regarding potential long-term health effects as PFAS accumulation occurs in humans from dietary and inhalation exposure routes. Chronic exposure may lead to adverse effects such as fertility issues or liver damage. Although a wide range of PFAS have been found in human samples, specifically human serum, there remains data gaps for what PFAS are present in human blood. Recent innovation in detection technology has led to the ability to more accurately …

Examining The Intersectional And Structural Issues Of Routine Healthcare Utilization And Access Inequities For Lgb People With Chronic Diseases, Shiya Cao, Mehreen Mirza, Sophia Silovsky, Nicole Tresvalles, Lucia Qin, Sarah Susnea

Statistical and Data Sciences: Faculty Publications

In the United States, although the gaps in health insurance coverage by sexual orientation have been closing since the implementation of the Affordable Care Act and legalization of same-sex marriage, the LGB group (i.e., lesbian, gay, bisexual) continues to report healthcare utilization and access inequities such as more delayed or unmet care. The extant research has often examined healthcare utilization and access inequities due to affordability (e.g., out-of-pocket costs). However, healthcare utilization and access inequities are only partially explained by cost reasons; there are non-cost reasons that have not been adequately empirically examined. The present study innovatively includes discrimination structural …

The Safety Kuznets Curve: Context In Occupational Safety, Andy Knickerbocker

ASEM Capstones

2025 ASEM 620 Capstone Project

Operationalizing Flourishing In Bsn Nursing Education: A Cipp- Driven Strategy, Kennedy E. Hochstedler, Elizabeth Morse

DNP Projects

Operationalizing Flourishing in BSN Nursing Education: A CIPP- Driven Strategy

Double Burden Stress In Women And The Role Of Psycho-Religious Worship In Alleviating It, Fahmi Mandala Putra, Zata Ismah, Rizky Indah Syahfitri, Citra Cahyati Nasution, Az-Zahra Atika Putri, Fitria Amirah, Tri Amelia Rahmitha Helmi

Folia Medica Indonesiana

It has been recognized that women are twice as likely to experience depression compared to men. In addition to biological vulnerability, there is also a combined effect of bearing the burden of household responsibilities while contributing financially through employment. One coping strategy that helps women endure these challenges is meditation, which in Islam includes the practice of dhikr (remembrance of God). This study aims to analyze the phenomenon of double burden stress in women and how psychoreligious practices can help reduce stress levels. The study employed a prospective cohort design, tracking the respondents' dhikr habits over a 21-day period. On …

Elm: The Case Of Experiential Programming, Matthew Miller, Lynette Campogiani

Faculty and Staff Publications & Presentations

Experiential Programs (EPs) provide immersive, destination-focused experiences within luxury resort settings. However, research has yet to apply the elaboration likelihood model (ELM) to examine how guests evaluate their experiences with EPs, particularly within luxury tourism or resort contexts. Using the ELM framework, this study examined how the experience of luxury resort EPs influences guests’ revisit intentions. Guests’ experiences were categorized into central and peripheral processing cues and qualitative interview responses were analyzed. The findings indicate that elements such as ambient music and scenic views associated with peripheral processing had a significantly stronger positive impact on guests’ intentions to return than …

Tennyson & Contemporary Science: Herschel’S Preliminary Discourse, A Book That Got Away, Patrick Scott

Faculty Publications

Discusses the rediscovery, provenance, and authenticity of the copy of John Herschel's Preliminary Discourse on the Study of Natural Philosophy (1831), with an ownership inscription by Tennyson dated 1843, and marginal markings on multiple pages, that was previously only known from a brief catalogue description for a 1924 auction.

Closeness, Conflict, And Achievement: The Role Of Parent–Child Relationships In Homeschooled And Public-Schooled Children, Celeste Gonçalves Tomaz

Honors Capstones

The parent–child relationship has been found to be a predictor of children’s academic and socio-emotional outcomes, with parent-child closeness linked to motivation and persistence (Mo & Singh, 2008; Silinskas & Kikas, 2022) and parent-child conflict associated with emotional and behavioral difficulties (Dotterer et al., 2008; Pinquart, 2017). The homeschooling context may increase these associations since children spend more time with their parents, who have caregiving and instructional roles (Padilla, 2021; Thomas, 2016). Even with growing research on academic and socio-emotional outcomes, few studies have examined whether the strength of the parent–child relationship is influenced negatively or positively by schooling type. …

State Of Technology Usage In Smaller Public Accounting Firms In 2025, Arun Kumararaj, Candice Hux

Honors Capstones

Prior research gives significant attention to technology usage of large public accounting firms, particularly the Big 4. However, limited evidence exists on the smaller public accounting firms, which constitute a majority of the public accounting field. In this study, we conducted semi-structured interviews with eight highly experienced professionals of smaller accounting firms. Findings reveal that firm size does not necessarily predict technological sophistication. Rather, individual leadership, including a single partner, emerges as a critical driver towards technological advancement. AI was primarily used for administrative tasks and, as of yet, the return on investment has been unclear. Despite this, all interviewees …

Technology, Education, Access, Communities And Healthcare: Teach Toward A Healthy Rural Wisconsin, Kathleen Abrahamson, Debbie Walrath, Shanon Brickner, Christine Davidson, Heidi Hansen, Seon Yoon Chung

Biennial Convention (CONV)

Purpose statement: The purpose of this project is to educate the future nursing workforce on tele-healthcare delivery skills that will reduce barriers to care and improve rural chronic illness outcomes in Wisconsin.

Background: Nearly one-third of Wisconsin citizens reside in rural areas (Wisconsin Policy Forum, 2023). Rural Wisconsinites are disproportionately at risk for adverse health outcomes (Rural Health Information Hub, 2023). A lack of available healthcare services and providers in rural Wisconsin compounds this risk. All non-metropolitan counties in Wisconsin experience a shortage of primary care providers (U.S. Department of Health & Human Services, 2023). Nurse-supported telehealth services provide a …

Changing Opinions: The Supreme Court After Dobbs, Lora E. Judge

Honors Theses

No abstract provided.

The Reception Of Neurodiversity Represented Within Netflix’S Wednesday, Anna Stevens

Graduate Theses & Dissertations

This paper explores how neurodiversity is represented through popular media - particularly Netflix's show Wednesday - and aims to discuss the effects this representation could have in regards to how it's received by the public, as well as those who are neurodiverse.

Proteome-Wide Association Study Of Prostate Cancer Risk Across Populations, Hua Zhong, Jingjing Zhu, Shuai Liu, Chong Wu, Liang Wang, Seamus P. Whelton, Catherine H. Marshall, Michael J. Blaha, Peter Durda, Xiuqing Guo, Craig W. Johnson, Henry J. Lin, Kent D. Taylor, Russell P. Tracy, Ronit I. Yarden, Ani W. Manichaikul, Stephen S. Rich, Jerome I. Rotter, Rajat Deo, Ruth F. Dubin, Peter Ganz, Lang Wu

School of Graduate Studies Faculty Publications

There is insufficient understanding of the molecular basis of prostate cancer (PCa) across different populations. We perform a large-scale proteome-wide association study (PWAS) to identify proteins with genetically regulated expression in plasma to be associated with PCa risk across populations. We develop genetic prediction models for expression of 1578, 1993, 1218, and 1390 proteins for African (n = 450), European (n = 758), Asian (n = 289), and Hispanic/Latino (n = 474) males, respectively, and evaluate associations of genetically regulated protein expression with PCa risk in 19,391 PCa cases and 61,608 controls of African population, 122,188 cases and 604,640 controls …

Strategies For Prolonging Ventricular Action Potential Duration Without Increasing Transmural Dispersion Of Repolarization, Candido Cabo

Publications and Research

Dispersion of repolarization results from a non-homogeneous recovery of excitability in cardiac tissue, and it is an important factor in arrhythmogenesis because it could lead to the initiation and maintenance of a variety of arrhythmias. Antiarrhythmic agents that prolong action potential duration (APD) by selectively blocking specific ion channels (like IKr) often increase dispersion of repolarization, which could result in a pro-arrhythmic risk. In this report, using computer models of the action potential of human epicardial, mid-myocardial, and endocardial myocytes, we have identified strategies to prolong APD without increasing transmural dispersion of repolarization. The first strategy, which involves blocking several …