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Advanced Ni-Co And Sn-Based Alloys Electrodeposition From Aqueous And Deep Eutectic Solvents, Narmin M. Hamadamin, Hassan H. Abdallah Dec 2025

Advanced Ni-Co And Sn-Based Alloys Electrodeposition From Aqueous And Deep Eutectic Solvents, Narmin M. Hamadamin, Hassan H. Abdallah

Polytechnic Journal

Electrodeposition is a pivotal technique in materials science, enabling the fabrication of metal and alloy coatings with tailored properties for diverse industrial applications. Traditional aqueous electrolytes, while widely used, present limitations such as narrow electrochemical windows, hydrogen evolution, and environmental concerns. Deep eutectic solvents (DESs) have emerged as promising alternatives, offering broader electrochemical windows, reduced toxicity, and enhanced solubility for metal salts. This review comprehensively examines the principles and advancements in electrodeposition from both aqueous and DES media, focusing on the deposition of Ni-Co and Sn-based alloys, the role of additives, the electrodeposition of metal powders, and surface analysis techniques. …


Exploring The Therapeutic Potential Of Fermented Apple Juice And Sidr Leaves Powder On Gut Microbiota Modulation And Neuropathy Relief In Diabetic Rats, Bakenam Ali Mohamed, Alyae M.S. Gabal, Gehan M. Morsy Dec 2025

Exploring The Therapeutic Potential Of Fermented Apple Juice And Sidr Leaves Powder On Gut Microbiota Modulation And Neuropathy Relief In Diabetic Rats, Bakenam Ali Mohamed, Alyae M.S. Gabal, Gehan M. Morsy

Baghdad Science Journal

Diabetes and its complications, particularly diabetic neuropathy, represent major health risks. This study investigated the potential of natural nutrients and bioactive compounds specifically fresh and fermented apple juice and sidr leaf powder to improve gut microbiota and alleviate neuropathy in diabetic rats. Seventy adult male Sprague–Dawley rats (180 ± 20 g) were assigned to six groups (11 rats each), while the diabetic control group (15 rats). Diabetes was induced by feeding a high-sucrose, high-fat (HSHF) diet and administering streptozotocin (45 mg/kg, intraperitoneally) during the 4th week. The groups included: healthy control; diabetic control; diabetic rats receiving fresh or fermented …


Classifying Glaucoma Disease Images Via Deep Neural Network Technique, Maysoon Jaaffar Rahim, Ali Abid Dawood Al-Zuky, Fatin Ezzat Muhy Al-Dean Al-Obaidi Dec 2025

Classifying Glaucoma Disease Images Via Deep Neural Network Technique, Maysoon Jaaffar Rahim, Ali Abid Dawood Al-Zuky, Fatin Ezzat Muhy Al-Dean Al-Obaidi

Baghdad Science Journal

A class of eye diseases known as glaucoma refers to a category of eye disease which is often associated with increased intraocular pressure, and can damage the eye by destroying nerve cells in the retina in addition to the eye's optic nerve. The accuracy of diagnosing glaucoma eye disease depends on the knowledge and experience of the ophthalmologist. Therefore, the need for automatic feature extraction from the retinal image is crucial for the diagnosis of glaucoma eye disease. The current article introduces a multi-layer deep neural network model with convolution and classification layers. The originality of the current search focuses …


On The Systems Of Distinct Representatives For The Family Of Sets Formed By Neighborhoods Of Vertices, Shahistha Hanif, K Arathi Bhat Dec 2025

On The Systems Of Distinct Representatives For The Family Of Sets Formed By Neighborhoods Of Vertices, Shahistha Hanif, K Arathi Bhat

Baghdad Science Journal

Currently, the theory of systems of distinct representatives is being carefully examined and reworked, often in a more general context. With time, considerable literature has grown, and new theories are proposed that require the system of distinct representatives to possess additional properties. In this article, one such context is considered. A graph is completely defined by the relationship between its vertices, also known as the neighborhood of vertices in graph theoretical context. Several parameters are defined based on the set of all neighborhoods of vertices and are explored. This article delves into the well-known problem of the existence of a …


The Assessment Of Soil Physico-Chemistry And Uptake Of Heavy Metals In Lumbricus Terrestris, Shahzad Anjum, Sidra Kanwal, Rana Manzoor Ahmad, Abdul Majid Khan, Muhammad Imran Dec 2025

The Assessment Of Soil Physico-Chemistry And Uptake Of Heavy Metals In Lumbricus Terrestris, Shahzad Anjum, Sidra Kanwal, Rana Manzoor Ahmad, Abdul Majid Khan, Muhammad Imran

Journal of Bioresource Management

Earthworms are considered ecosystem engineers, playing an essential role in soil fertility. Heavy metals are supposed to remain linked to soil for a very long time and can bio-accumulate swiftly in soil microbes, posing a severe threat to the environment. The current study was designed to investigate the bio-accumulation of heavy metals in Lumbricus terrestris and the impact of soil pH and texture on earthworm morphology and densities near industrial areas of the district of Okara, Punjab, Pakistan. The samples were collected from the locations of different industries using the quadrate method and analyzed for heavy metal accumulation by using …


Psychological Responses To Interval And Continuous Exercise In People Living With Hiv: A Single-Blind, Counterbalanced, Crossover Study., Phelipe Wilde, Victor S. De Queiros, Jason R. Jaggers, Angelo Sabag, Julio M. Alves, Elaine Fernandes, Robert F.C. Rocha, Paulo F. De Almeida-Neto, Ronaldo Vagner Thomatieli-Santos, Paulo Moreira Silva Dantas Dec 2025

Psychological Responses To Interval And Continuous Exercise In People Living With Hiv: A Single-Blind, Counterbalanced, Crossover Study., Phelipe Wilde, Victor S. De Queiros, Jason R. Jaggers, Angelo Sabag, Julio M. Alves, Elaine Fernandes, Robert F.C. Rocha, Paulo F. De Almeida-Neto, Ronaldo Vagner Thomatieli-Santos, Paulo Moreira Silva Dantas

Faculty and Staff Scholarship

Abstract
Aim: This study compared acute psychological responses to a single session of low-volume high-intensity interval exercise (HIIE-LV), high-volume highintensity interval exercise (HIIE-HV), and moderate-intensity continuous exercise (MICE) in people living with HIV, and healthy controls using a randomized, counterbalanced crossover design. Methods: The participants (people living with HIV, and healthy controls) completed three exercise sessions in randomized order: HIIE-HV (4  4 min at 80% of maximal power output [Wmax]), HIIE-LV (10  60 s at 90% Wmax), and MICE (30 min at 60% Wmax). Psychological outcomes included affective response assessed by the Feeling Scale, exercise enjoyment and future exercise intention …


The Impact Of Targeting Traf2 And Nck-Interacting Protein Kinase On Antitumor Effect And Tumor Immune Environment In C-Myc-High Sclc, Azusa Tanimoto, Kavya Ramkumar, C Allison Stewart, Bingnan Zhang, Kyle Concannon, Robert J Cardnell, Li Shen, Qi Wang, Jing Wang, Carl M Gay, Lauren Averett Byers Dec 2025

The Impact Of Targeting Traf2 And Nck-Interacting Protein Kinase On Antitumor Effect And Tumor Immune Environment In C-Myc-High Sclc, Azusa Tanimoto, Kavya Ramkumar, C Allison Stewart, Bingnan Zhang, Kyle Concannon, Robert J Cardnell, Li Shen, Qi Wang, Jing Wang, Carl M Gay, Lauren Averett Byers

Faculty, Staff and Student Publications

Introduction: Wnt/β-catenin signaling pathway activation contributes to tumorigenesis and chemo-resistance in SCLC, yet clinical attempts to target this pathway have been unsuccessful. TRAF2 and NCK-interacting protein kinase (TNIK), an essential nuclear activator of Wnt/β-catenin target genes, has not yet been validated as a viable therapeutic target in SCLC. Here, we validated that TNIK inhibition is a promising approach for personalized anticancer therapy in SCLC.

Methods: We correlated the IC50 values of a TNIK inhibitor, NCB-0846, with proteomic profiling (reverse phase protein array) data across 28 SCLC cell lines. Cytokine array analysis was performed to quantify changes in 105 cytokines after …


Emotive Immersion: Eeg-Driven Ai Art In Immersive Visual Spaces (Full Dome), Yuming Chen, Gianni Corino Dec 2025

Emotive Immersion: Eeg-Driven Ai Art In Immersive Visual Spaces (Full Dome), Yuming Chen, Gianni Corino

School of Art, Design and Architecture

This paper proposes a rethinking of the “Future Screen” through the integration of affective computing, generative AI, and immersive spatial display. As an advanced screen paradigm, the full dome environment transcends flat, passive interfaces and enables dynamic, multisensory, and emotionally adaptive media experiences (Von Chamier-Waite, 2013). Building on this potential, the research presents Coids, an interactive dome installation. In this work, real-time emotional states are captured using EEG-based emotion recognition. These inputs dynamically shape AI-generated visuals within a shared immersive setting.Drawing on theories of immersion, presence, AI generated visuals and affect, the study explores how physiological data, even from low-resolution …


Reduction Of Ground Vibration Dynamic Effects Induced From Mining Blasting On Nearby Structures: Case Study, Ayman M. Ismail, Sherif H. M. Hassnien Dec 2025

Reduction Of Ground Vibration Dynamic Effects Induced From Mining Blasting On Nearby Structures: Case Study, Ayman M. Ismail, Sherif H. M. Hassnien

HBRC Journal

One of the primary challenges confronting the quarrying industry pertains to the ground vibrations resulting from the blasting activities in cement quarries, as these vibrations have the potential to inflict significant damage upon adjacent structures. Within the context of this scholarly article, an examination is conducted on a residential edifice situated in the 15th of May city in Cairo, Egypt, which has been impacted by the proximate mining blasting. The ground velocity at the foundation of this residential building is assessed, mainly from the peak particle’s velocity prospective. Subsequently, a finite element model (FEM) of the building is formulated and …


Carbon Nanotubes Enhanced Tio2/G-C3N4 As A Potential Nanocomposite Material For Impedance-Type Humidity Sensors, Mohamed Morsy Dec 2025

Carbon Nanotubes Enhanced Tio2/G-C3N4 As A Potential Nanocomposite Material For Impedance-Type Humidity Sensors, Mohamed Morsy

HBRC Journal

The development of high-performance humidity sensors based on nanotechnology has become critical for different applications. This work focuses on the fabrication and characterization of impedance-type humidity sensors based on graphitic carbon nitride, titanium dioxide, and carbon nanotubes. The prepared materials comprise g-C3N4, g-C3N4/TiO2, and g-C3N4/TiO2/CNTs, which have been synthesized through the co-precipitation method. The properties of the nanocomposites have been verified through different characterization techniques that confirm the phase composition and morphology. The humidity-sensing response of the prepared materials was tested within a humidity range of 11%–97% RH at different testing frequencies. The unique structure of …


A Proposed Model For Assessing The Impact Of Sustainable Practices On The Affordability Of Affordable Housing In Egypt Using Ahp, Ayman M Zakaria Eraqi, Omnia Nagy Abd El-Hafez, Amany Nagy Abd El-Hafez Dec 2025

A Proposed Model For Assessing The Impact Of Sustainable Practices On The Affordability Of Affordable Housing In Egypt Using Ahp, Ayman M Zakaria Eraqi, Omnia Nagy Abd El-Hafez, Amany Nagy Abd El-Hafez

HBRC Journal

Amid rising inflation and a housing crisis in Egypt, this research develops a model to assess the affordability of sustainable housing for low- and middle-income groups by integrating environmental, social, and economic sustainability criteria. The research methodology used Analytic Hierarchy Process (AHP) to evaluate the relative weights of sustainability criteria in housing projects. Based on their impact on construction costs, these criteria were classified by experts into five main groups: Design Criteria (preliminary studies, initial cost, environmental planning), Neighborhood Criteria (location, design, management), Social and Cultural Criteria (privacy and safety), Natural Resource Sustainability (water, energy), Housing Unit Criteria (design and …


Structural Behavior Of Reinforced Concrete Columns Under Eccentric Loads Strengthened By Steel Jackets Filled With Normal And High-Strength Concrete, Mahmoud Ahmed M. Amin, Mahmoud Mostafa El Hawary, Ahmed Shaheen, Ibrahim M. Mashhour Dec 2025

Structural Behavior Of Reinforced Concrete Columns Under Eccentric Loads Strengthened By Steel Jackets Filled With Normal And High-Strength Concrete, Mahmoud Ahmed M. Amin, Mahmoud Mostafa El Hawary, Ahmed Shaheen, Ibrahim M. Mashhour

HBRC Journal

Reinforced concrete (RC) columns are essential structural components in buildings and infrastructure, providing vertical load support and stability. However, these columns can be degraded over time due to various factors, such as environmental exposure, seismic events, and increased loading demands. As a result, the need for effective and reliable column-strengthening techniques arises to ensure the safety, durability, and longevity of structures. The main objective of this study is to investigate how fully strengthening damaged columns affects load-bearing capacity and overall structural performance. Moreover, this study tested thirteen reinforced concrete columns during the experimental program. The original dimensions of these columns …


Finite Element Analysis Of Double-Skin Steel-Concrete Composite Shear Walls With Portal Frames Under Monotonic Shear Loading, Islam Salama, Mahmoud M. Elnahla, Hasan Maaly, Ibrahim T. Arafa Dec 2025

Finite Element Analysis Of Double-Skin Steel-Concrete Composite Shear Walls With Portal Frames Under Monotonic Shear Loading, Islam Salama, Mahmoud M. Elnahla, Hasan Maaly, Ibrahim T. Arafa

Almaaqal Journal of Sustainability and Emerging Technology

This study investigates the structural performance of double-skin profiled steel-concrete composite shear walls (DSPCW) integrated with portal frames under monotonic shear loading using a validated finite element model. The FE framework, developed in ABAQUS, accurately predicts experimental load-displacement behavior, stress distribution, and failure modes, demonstrating its reliability for parametric exploration. A comprehensive analysis evaluates the effects of steel grade, fastener quantity and distribution, panel openings, and comparative performance against traditional vertical bracing systems. Key findings reveal that DSPCW panels with engineered cementitious composite concrete cores exhibit 1.5–2 times higher shear capacity than conventional braced frames at comparable mass, emphasizing their …


A Generalized Convolutional Autoencoder Framework For Seismic Waveform Compression, Emad B. Helal, Mostafa M. Ibrahim, Ali G. Hafez Dec 2025

A Generalized Convolutional Autoencoder Framework For Seismic Waveform Compression, Emad B. Helal, Mostafa M. Ibrahim, Ali G. Hafez

Almaaqal Journal of Sustainability and Emerging Technology

Effective data compression methods have become crucial as the amounts of seismic data are growing exponentially. Due to extensive surveys and ongoing real-time monitoring, compression not only reduces storage requirements but also optimizes communication bandwidth between remote seismic stations and central processing hubs. In this paper, a generalized autoencoder-based compression framework is proposed.. Its primary innovation is a single, fixed network architecture that delivers robust performance across low, medium, and high compression ratios (CRs). Performance was compared with a dynamic pooling-based model and three wavelet-based methods (db4, sym8, coif3) across CRs from 2 to 100. Experimental results demonstrate that the …


A Review Of Machine Learning Methods In Energy Management System, Mays Sattar Al-Fatllah, Zaipatimah Ali, Aidil Azwin Zainul Abidin Dec 2025

A Review Of Machine Learning Methods In Energy Management System, Mays Sattar Al-Fatllah, Zaipatimah Ali, Aidil Azwin Zainul Abidin

Almaaqal Journal of Sustainability and Emerging Technology

Traditional energy sources are vital for energizing residences and industries. Nonetheless, they meet considerable obstacles, such as deteriorating infrastructure, ecological decline, resource exhaustion, price fluctuations, and a disparity between real-time demand and supply. Conversely, renewable energy sources offer cleaner and more sustainable energy sources. Renewable energy mitigates the pollution caused by carbon and greenhouse gas emissions in traditional power systems. Incorporating renewable energy into a power system needs an efficient management system to keep stability and improve power use. Modern energy management systems (EMS) face a significant challenge in controlling renewable and non-renewable energy sources. The challenges encompass intermittent and …


Multivariate Optimization Of Nonlinear Response Functions Using Central Composite Design, Hussein M. Hussein, Bassma H. Elwakil, Esraa Abdelhamid Moneer, Sara H. Akl, Yahya H. Shahin Dec 2025

Multivariate Optimization Of Nonlinear Response Functions Using Central Composite Design, Hussein M. Hussein, Bassma H. Elwakil, Esraa Abdelhamid Moneer, Sara H. Akl, Yahya H. Shahin

Almaaqal Journal of Sustainability and Emerging Technology

This study addresses critical challenges in multivariate optimization by: (1) developing efficient strategies for optimizing nonlinear response functions in high-dimensional parameter spaces, (2) quantifying comparative performance of traditional versus statistical design methodologies, (3) establishing mathematical frameworks for parameter interactions, and (4) validating results through comprehensive statistical analysis. A dual-phase optimization framework combined One-Variable-At-a-Time (OVAT) screening with Central Composite Design-based Response Surface Methodology (CCD-RSM). Five parameters were evaluated using rotatable CCD (α= 2.378) with 50 design points. Statistical analysis included analysis of variance (ANOVA), regression modeling, interaction quantification, and cross-validation. CCD-RSM demonstrated superior performance with model predictability improving from …


Machine Learning Framework For Automatic Classification Of Nano-Seismic Signals Preceding Earthquakes, Ghada Ali, Ali G. Hafez, Sayed Hasaneen, Hamed Nofel, Nabeel Al-Atwan, Ahmed Mohamed Dec 2025

Machine Learning Framework For Automatic Classification Of Nano-Seismic Signals Preceding Earthquakes, Ghada Ali, Ali G. Hafez, Sayed Hasaneen, Hamed Nofel, Nabeel Al-Atwan, Ahmed Mohamed

Almaaqal Journal of Sustainability and Emerging Technology

Nano-seismicity preceding earthquakes has many applications in fault prediction, in structure health monitoring, and in enhancing fault and source parameter determination. Not all earthquakes are preceded by these precursors; therefore, there is a need to identify P-wave arrivals that are preceded by these nano signals, which will eliminate errors in P-wave arrival timing. The current work introduces topologies capable of automatically categorizing the arrivals with nano-seismic precursors. The proposed methods are trained on datasets extracted from stations belonging to Egyptian National Seismic Network (ENSN). These records contain both P-wave arrivals preceded by such nano precursors and other records without these …


Optimizing Bioethanol Production Using Design Of Experiments For Sustainable Biofuel Development, Hussein M. Hussein, Yahya H. Shahin, Ihab A. Moneam Dec 2025

Optimizing Bioethanol Production Using Design Of Experiments For Sustainable Biofuel Development, Hussein M. Hussein, Yahya H. Shahin, Ihab A. Moneam

Almaaqal Journal of Sustainability and Emerging Technology

This study presents a statistically optimal approach for bioethanol production from sugarcane bagasse (SCB) using alkaline pretreatment, enzymatic hydrolysis, and fermentation processes. To maximize cellulose yield, four extraction parameters—solvent type, concentration, temperature, and time—were optimized using a Taguchi statistical model. The Taguchi-optimized extraction yields 11.3% increased cellulose recovery relative to cellulose recovered via non-optimized extraction methods (i.e., alkaline treatment with 6% NaOH at 90 °C for 3 hours). This yielded 45.20% cellulose (w/w), with 37.80% weight loss (predicted weight loss was 36.94%). Statistical analysis of extraction results verified solvent type (p = 0.0022) and temperature (p = 0.0007) to be …


A Smart City Transformation Survey: Using Intelligent Buildings To Promote Smart Cities, Salma A. Alhashimi, Majid A. Alwan, Ali N. Aliedani Dec 2025

A Smart City Transformation Survey: Using Intelligent Buildings To Promote Smart Cities, Salma A. Alhashimi, Majid A. Alwan, Ali N. Aliedani

Almaaqal Journal of Sustainability and Emerging Technology

The challenges of urbanization have been greatly aided by the integration of cutting-edge technology into smart buildings and cities. In smart cities and buildings, machine learning and the Internet of Things are essential for boosting sustainability, increasing safety, and optimizing resource use. In order to enable more effective, connected, and comfortable living in urban settings, this work has introduced the relationship between creative technology and buildings. It also discusses the regulatory frameworks for smart cities and emphasizes the importance of standardization in this regard.


Braingenebot: A Gpt-Engineered, User-Driven Genetic Data Exploration With Polygenic Risk Scores Ranking In Alzheimer’S Disease, Guan Ou, Zhongming Zhao Dec 2025

Braingenebot: A Gpt-Engineered, User-Driven Genetic Data Exploration With Polygenic Risk Scores Ranking In Alzheimer’S Disease, Guan Ou, Zhongming Zhao

Faculty, Staff and Student Publications

Background

Polygenic risk scores (PGSs) aggregate the effects of multiple genetic variants to attribute to disease susceptibility, and have been applied to numerous complex diseases including Alzheimer's disease (AD). However, as omics and phenotypic data grow exponentially, reconciling findings across studies with differing ancestral backgrounds, study designs, and statistical methodologies remains a pressing issue. Efficiently extracting biologically relevant insights from this expanding body of data is equally challenging, especially for diseases driven by complex interactions among genetic, environmental, and lifestyle factors.

Method

To address these challenges, we introduce BrainGeneBot, an AI‐driven chatbot framework that automates genetic data analysis and bridges …


Cover And Content Dec 2025

Cover And Content

Turkish Journal of Chemistry

No abstract provided.


Novel Spectrophotometric Method For The Determination Of Paclitaxel Through Complex Formation With Osmium, Basima A.A.Saleem, Salim A. Mohammed, Amer Th. Al-Taee Dec 2025

Novel Spectrophotometric Method For The Determination Of Paclitaxel Through Complex Formation With Osmium, Basima A.A.Saleem, Salim A. Mohammed, Amer Th. Al-Taee

Turkish Journal of Chemistry

Paclitaxel (Pac) is an important anticancer bioactive compound, and the availability of an accurate and robust analytical method for its quantification is of utmost importance. In this investigation, a novel, direct, and reliable spectrophotometric method has been proposed for the estimation of Pac via a complex formation reaction with osmium (Os). The method was based on the reaction of Pac with Os tetroxide, which produced a yellowish-brown complex. The resulting complex is soluble in water and displays a maximum absorption peak at 482 nm. The reaction conditions, including reactant concentration, pH, temperature, and reaction time, were optimized to obtain the …


Synthesis, Characterization, Antimicrobial, Antioxidant, And Antiinflammatory Evaluation And Molecular Docking Studies Of N-((2-Hydroxy-3-(2-(Substitutedbenzylidene)Hydrazine-1-Carbonyl)Naphthalen-1-Yl)(3-Nitrophenyl/3,4-Dimethoxyphenyl)Methyl)Acetamide Derivatives, Shikha Kamboj, Alka Yadav, Samridhi Thakral, Rekha Tanwar, Sunil Kumar, Vikramjeet Singh Dec 2025

Synthesis, Characterization, Antimicrobial, Antioxidant, And Antiinflammatory Evaluation And Molecular Docking Studies Of N-((2-Hydroxy-3-(2-(Substitutedbenzylidene)Hydrazine-1-Carbonyl)Naphthalen-1-Yl)(3-Nitrophenyl/3,4-Dimethoxyphenyl)Methyl)Acetamide Derivatives, Shikha Kamboj, Alka Yadav, Samridhi Thakral, Rekha Tanwar, Sunil Kumar, Vikramjeet Singh

Turkish Journal of Chemistry

Hydrazone chemistry has become important and plays a key role in the development of organic compounds. Hydrazones can be useful pharmacophores for creating novel derivatives, owing to their broad range of activities. In this study, a series of N-((2-hydroxy-3-(2-(substitutedbenzylidene)hydrazine-1-carbonyl)naphthalen-1-yl)(3-nitro-phenyl/3,4-dimethoxyphenyl)methyl)acetamide derivatives were prepared, characterized by FTIR, 1H-NMR, 13C-NMR, and mass spectroscopy, and evaluated for their antimicrobial, antiinflammatory, and antioxidant activities along with in silico studies. The substituted derivatives were synthesized by the reaction of acetonitrile, chlorosulphonic acid, and substituted benzaldehyde with the hydrazones. The antimicrobial evaluation showed that compound 3i had more antimicrobial potential than the other tested molecules. Compound 3j …


Enhancing Analytical Performance Of Tyrosinase-Based Sensors With Nanoparticles For Detection Of Isoproterenol, Aysel Oktay, Sevi̇nç Kurbanoğlu, Gülsüm Gündoğdu, Cem Bülent Üstündağ, Frieder W. Scheller, Aysu Yarman Dec 2025

Enhancing Analytical Performance Of Tyrosinase-Based Sensors With Nanoparticles For Detection Of Isoproterenol, Aysel Oktay, Sevi̇nç Kurbanoğlu, Gülsüm Gündoğdu, Cem Bülent Üstündağ, Frieder W. Scheller, Aysu Yarman

Turkish Journal of Chemistry

In this work, electrochemical biosensors utilizing tyrosinase (Tyr) for the detection of the nonselective beta-adrenergic agonist isoproterenol (ISO) are presented. Three different configurations for immobilizing Tyr on a graphite electrode (GE) are compared: (1) GE modified with poly(diallyldimethylammonium chloride) (PDADMAC), PDADMAC/Tyr/GE; (2) PDADMAC combined with iridium nanoparticles (IrNPs) in a stepwise preparation, resulting in PDADMAC/IrNPs/Tyr/GE; and (3) a composite of PDADMAC and IrNPs mixed with Tyr at a 1:1 (v:v), forming PDADMAC/(IrNPs-Tyr)/GE. Surface morphology was characterized using scanning electron microscopy (SEM). Cyclic voltammetry (CV) and amperometry were applied to characterize the biosensor’s performance. Within the linear range of 5 μM …


Synthesis, Characterization, And Theoretical Study Of New Cocrystals And Charge-Transfer Compounds, Zari̇fe Si̇bel Şahi̇n, Zeki̇ Kartal Dec 2025

Synthesis, Characterization, And Theoretical Study Of New Cocrystals And Charge-Transfer Compounds, Zari̇fe Si̇bel Şahi̇n, Zeki̇ Kartal

Turkish Journal of Chemistry

This study used single-crystal X-ray diffraction, elemental analysis, infrared (IR) spectroscopy, theoretical nuclear magnetic resonance (NMR), and theoretical ultraviolet spectroscopy to characterize 3 newly synthesized crystalline compounds. Additionally, the nonlinear optical, highest occupied molecular orbital energies, lowest occupied molecular orbital energies, band gap, molecular electrostatic potential, and thermodynamic parameters of the 3 crystalline compounds were examined. The strong correlation between experimental IR spectra and theoretical NMR chemical shifts confirmed the accuracy of computational predictions. The molecular formulas of the 3 newly synthesized crystalline compounds, each containing different ligand molecules, were: C8H14O4·2(C6H4N2), C5H7N2·NCS, and Ni(CN)4·2(C5H7N2)·2(H2O) for compounds 1, 2, and 3, …


New Bis-Piperazine Derivatives: Synthesis, Characterization (Ir, Nmr), Gamma-Ray Absorption, Antimicrobial Activity, Molecular Docking And Dynamics Study, Yasemi̇n Ünver, Arzu Coşkun, Fati̇h Çeli̇k, Hali̇l İbrahi̇m Güler, Kadri̇ye İnan Bektaş Dec 2025

New Bis-Piperazine Derivatives: Synthesis, Characterization (Ir, Nmr), Gamma-Ray Absorption, Antimicrobial Activity, Molecular Docking And Dynamics Study, Yasemi̇n Ünver, Arzu Coşkun, Fati̇h Çeli̇k, Hali̇l İbrahi̇m Güler, Kadri̇ye İnan Bektaş

Turkish Journal of Chemistry

A series of novel bis-piperazine derivatives (2a–2f) were synthesized and structurally characterized via Fourier transform-infrared and nuclear magnetic resonance spectroscopic techniques. Their gamma-ray shielding efficiencies were investigated through simulations on the Monte Carlo-based Geant4-GATE platform, and the results were benchmarked against data obtained from the XCOM and Phy-X software. A simulation model incorporating an NaI scintillation detector and a point gamma source was developed. Key shielding parameters, including mass attenuation coefficient, linear attenuation coefficient, half-value layer, and mean free path (MFP), were evaluated at gamma energies of 80, 120, 662, 1173, and 1332 keV. Additionally, the energy absorption buildup factor …


Synthesis Of Biogenic Silver Nanoparticles From Apricot Kernel Extracts For The Colorimetric Determination Of Gold, Ayça Gi̇rgi̇n, Hi̇lal Akbiyik, Buse Tuğba Zaman, Omid Nejati, Ayça Bal Öztürk, Gülten Çeti̇n, Sezgi̇n Bakirdere Dec 2025

Synthesis Of Biogenic Silver Nanoparticles From Apricot Kernel Extracts For The Colorimetric Determination Of Gold, Ayça Gi̇rgi̇n, Hi̇lal Akbiyik, Buse Tuğba Zaman, Omid Nejati, Ayça Bal Öztürk, Gülten Çeti̇n, Sezgi̇n Bakirdere

Turkish Journal of Chemistry

Gold is abundant in nature, however, precise and reliable analytical methods for its detection are required stemming from its increasing prevalence in environmental, biological, and industrial systems, as well as the growing interest in understanding its function in living organisms and its effects on human health. This study investigates the use of biogenically synthesized silver nanoparticles (AgNPs) for the preconcentration and determination of gold ions prior to determination by UV-Vis spectrophotometry. AgNPs were synthesized by reducing silver nitrate through the use of an apricot kernel extract as both reducer and stabilizer agent. The colloidal yellowish AgNPs interacted with gold ions, …


Structural Categorization And Identification Of Electrostatic Interactions In Two Proposed Human Serum Albumin Dimerization Patterns And Dipyridamole Interaction, Haluk Çeti̇nok, Veyi̇s Karakoç, Erol Erçağ, Yusuf Meli̇h Şekerer, Hasan Demi̇rci̇ Dec 2025

Structural Categorization And Identification Of Electrostatic Interactions In Two Proposed Human Serum Albumin Dimerization Patterns And Dipyridamole Interaction, Haluk Çeti̇nok, Veyi̇s Karakoç, Erol Erçağ, Yusuf Meli̇h Şekerer, Hasan Demi̇rci̇

Turkish Journal of Chemistry

Human serum albumin (HSA) is a ubiquitous, multifunctional protein responsible for the systemic distribution of both endogenous metabolites and exogenous pharmaceuticals. Its inherent properties, particularly its ability to seep into tissues and its multiple ligand-binding sites, have rendered HSA an attractive vehicle for nanoparticle-based drug delivery systems, particularly for cancer targeting. In this study, we present high-resolution crystallographic data revealing two distinct dimerization patterns of HSA (Protein Data Bank [PDB] ID: 9V61) obtained under high-concentration crystallization conditions, along with results from dipyridamole docking. Both dimer types demonstrate extensive interface areas and a significant number of electrostatic interactions. Comparative analysis with …


Α-Glycosidase Activity Of Novel Coumarin–Triazole–Coumarin Dyads, Ersi̇n Şi̇ri̇n, Esra Sevi̇mli̇, Gökçe Seyhan, Burak Barut, Yunus Kaya, Baybars Köksoy Dec 2025

Α-Glycosidase Activity Of Novel Coumarin–Triazole–Coumarin Dyads, Ersi̇n Şi̇ri̇n, Esra Sevi̇mli̇, Gökçe Seyhan, Burak Barut, Yunus Kaya, Baybars Köksoy

Turkish Journal of Chemistry

Novel coumarin–triazole–coumarin dyads were synthesized and characterized, and their α-glycosidase inhibitory activities were evaluated spectrophotometrically. Compound 4e exhibited the most pronounced inhibitory effect, with an IC50 value of 38.98 ± 0.77 μM. The IC50 values for 4d and 4a were 93.55 ± 1.70 μM and 95.04 ± 3.55 μM, respectively. The Lineweaver–Burk plot showed that 4e inhibited α-glycosidase in a mixed type. In addition, the Ki value obtained from the Dixon plot was 19.95 ± 0.15 μM for α-glycosidase.


Efficient Recovery Of Y3+ From Aqueous Media Using Mdlm Technique:Transport Behavior And Kinetic Modeling, Volkan Demi̇rel, Ramazan Donat, Hacer Şensöz Dec 2025

Efficient Recovery Of Y3+ From Aqueous Media Using Mdlm Technique:Transport Behavior And Kinetic Modeling, Volkan Demi̇rel, Ramazan Donat, Hacer Şensöz

Turkish Journal of Chemistry

This study investigates the extraction behavior of Y³⁺ ions using a Multi-Dropped Liquid Membrane (MDLM) system that employs di(2-ethylhexyl) phosphoric acid (D₂EHPA) as the carrier ligand. The focus is on the system’s ability to transport ions between aqueous phases selectively. The extracted complex was analyzed spectrophotometrically via ultraviolet–visible (UV–Vis) measurements after complexation with 0.05% Arsenazo III. The aim of this study was to determine the influence of the optimum D₂EHPA carrier concentration, together with the pH and temperature conditions of the donor and acceptor phases, on the system’s extraction performance. Accordingly, a series of extraction experiments was performed at different …