Digital Commons Network^™

Chronicles Of Film Tourism: An Integrative Review And Future Research Directions, Sangkyun Kim, Anton Klarin, Stijn Reijnders, Qijie Xiao, Nicky Van Es

Research outputs 2022 to 2026

This study triangulates historiographical and scientometric reviews to provide a systems perspective on film tourism. The three phases of historiographical analysis (exploration, growth, and maturity) correspond to the three clusters of scientometric analysis: (i) initial research exploring film tourism development and management, (ii) growing the field through studies on film tourists’ perceptions and practices, and (iii) reaching maturity through extending research into different cultural contexts and meaning-making processes. Based on the analysis, we offer a set of directions for future research, including the need to integrate sustainability research and film tourism studies in developing country contexts, as well as intertextuality …

Reflections From A Community Capacity Building Forum To Support People Bereaved By Suicide, Colleen Carlon, Jacquie Tarrant, Marie Eckersley, Priscilla Vindin

Research outputs 2022 to 2026

An estimated half the population may be impacted by suicide loss. The combination of grief and trauma makes the experience particularly complex. Recognised as the most stigmatised of all sudden losses people bereaved by suicide are in sociocultural contexts that disrupt constructive grief processes and create barriers for help seeking and supportive responses. Effecting change in this context poses a significant health promotion challenge. Social workers in the South West Region of Western Australia sought to develop and deliver a unique postvention approach aimed at strengthening the self-support capacity of people bereaved by suicide while building broader community capacity for …

Uncovering The Intervening Mechanisms In The Relationship Between Technological Stressors And Individual And Work-Related Consequences, Saeid Nosrati, Seongseop Kim, Dori Davari, Jaehee Gim, Antony King Fung Wong

Research outputs 2022 to 2026

This study examined how workplace telepressure and cyber incivility, as work-related stressors, affect individual and work-related outcomes in hospitality employees, using a mixed-methods approach. After developing a draft, following a thorough literature review and interviews with hotel staff, the drafted questions were refined through a pre-test and a pilot test. Finally, the main survey was conducted with 792 hotel staff in China. Structural equation modeling was performed using Mplus (Version 8.3) to test both direct and serial mediating effects. It was found that workplace telepressure and cyber incivility, through the serial mediating effect of technostress and poor mental health, had …

Women In The Australian Mining Industry, Michelle Gander, Fleur Sharafizad, Aglae Hernandez Grande, Heidi Vivian, Mahan Poorhosseinzadeh, Kate Blackwood

Research outputs 2022 to 2026

This report synthesises existing research on women’s participation in the Australian mining industry to identify the structural and cultural factors shaping gender inequality across the sector.

Drawing on research conducted over the past four decades, the report brings together what is currently known about how mining workplaces operate and how organisational practices, work arrangements, and site cultures shape the experiences of women across the sector. While many companies have introduced diversity and inclusion initiatives aimed at improving gender balance, the evidence suggests that challenges persist in areas such as operational roles, leadership pathways, and workplace culture.

Specifically, the report examines …

A Social And Cognitive Psychological Perspective On The Assumptions Underlying The Rorschach Inkblot Test, Igor Areh, Fanny Verkampt, Alfred Allan, Christian N.L. Olivers

Research outputs 2022 to 2026

Introduction/literature findings: The century-old Rorschach test is as controversial as it is well-known, and the subject of an ongoing, but still inconclusive debate about its validity and reliability. This debate is not inconsequential, as the test is still frequently used in clinical and forensic work. In addition to the psychometric aspects, there are social and cognitive psychological assumptions that underlie the test and that have hitherto been underexposed. We identify some of these assumptions and examine them with reference to contemporary social and cognitive psychological research. Discussion: Despite empirical evidence for some of the assumptions underlying the Rorschach test, most …

Aerobic Exercise Increases Brain-Derived Neurotrophic Factor (Bdnf) In Sub-Acute Stroke: A Randomized Controlled Trial, Christopher P. Mackay, Suzanne Kuys, Mia Schaumberg, Li Ann Leow, Sandy Brauer

Research outputs 2022 to 2026

Background: Brain-derived neurotrophic factor (BDNF) is a key neurotrophin due to its role in neuron process outgrowth, plasticity, and neuronal survival. Aerobic exercise can induce BDNF release and may ultimately maximize post-stroke recovery. Objectives: This study aimed to determine if a program of moderate-to-high-intensity aerobic exercise increased concentrations of BDNF in subacute stroke survivors compared to usual care. Methods: A parallel-group, RCT was undertaken in people with subacute stroke undergoing rehabilitation. Participants were randomly allocated to usual care (control group) or usual care plus an 8-week program of moderate-high intensity treadmill walking (3 x 30 min sessions per week) (experimental …

And Then Covid Happened: The Impact Of The Pandemic On Transition Temporalities For Mobile Youth, Anita Harris, Giulia Marchetti, Loretta Baldassar

Research outputs 2022 to 2026

This article explores how the COVID-19 pandemic affected mobile young people’s experiences of the temporality of transitions to adulthood. Young people are today the most mobile population globally, and mobility has necessarily become integral to youth-to-adulthood transitions. By adopting transition temporalities as an analytical key, we consider the impact of pandemic immobility on the transition experiences of young movers who, when the pandemic hit, found themselves stuck not only in place but also in time. Drawing on in-depth interviews undertaken during the pandemic with transnationally mobile young people (aged 18–30) who left Australia for abroad or moved to Australia from …

Developing Consumer Consensus On Remote Assessment And Management Of Physical Function In Older Adults (Ramp): International Modified Delphi Process, Elsa Dent, Christopher Hurst, Jack Dalla Via, Jackson J. Fyfe, Paul Jansons, Eleanor J. Hayes, Gary Skinner, Marc Sim, Mylene Aubertin-Leheudre, Sabine Britting, Fanny Buckinx, Gavin Connolly, Lora Giangregorio, Jennifer R.A. Jones, Pauline Kelly, Robert Kob, Suzanne N. Morin, Girish Nandakumar, Lucas B.R. Orssatto, Maria Pearson, Daniel Pinto, Esmee M. Reijnierse, Catherine M. Said, Mohamed Salem, Vina P.S. Tan, Rosanna Tran

Research outputs 2022 to 2026

Background: Remote health care delivery, including the use of digital health interventions, is emerging as a tool for assessing and managing physical function, but its design and implementation often overlook the needs and preferences of older adult end users. Objective: The primary aim of this modified Delphi process was to develop consumer consensus on preferences for remote assessment and management of physical function in older adults. Methods: Research and consumer experts of the Remote Assessment and Management of Physical Function in Older Adults (RAMP) Working Group co-developed the Round 1 Delphi survey, which was advertised to consumers (adults aged ≥60 …

Do Combined Resistance And Aerobic Exercise Programs Cause An Interference Effect In Women With Breast Cancer? A Systematic Review And Network Meta-Analysis, Pedro Lopez, Anderson Rech, Maria Petropoulou, Caroline B. Silveira, Talita Molinari, Cindranne Torres Muller, Priscila Casara, Francesco Bettariga, Favil Singh, Régis Radaelli

Research outputs 2022 to 2026

Background: Exercise medicine has gained significant recognition owing to its demonstrated benefits throughout the breast cancer treatment continuum. While resistance exercise (RE) promotes improvements in lean mass and muscle strength, aerobic exercise (AE) enhances cardiorespiratory fitness, with several studies investigating both exercise modes in patients with breast cancer. However, because of an effect often referred to as interference effect, it is hypothesised that combining resistance and aerobic exercise (COMB) may compromise gains in lean mass and muscle strength and other outcomes in cancer populations. Objective: This study aims to investigate the presence of an interference effect from prescribing COMB compared …

Energy Poverty, Economic Growth And Environmental Degradation In South Asia: Do Energy Resources Matter?, Memona Rasheed, Hooi Hooi Lean, Nam Foo

Research outputs 2022 to 2026

Developing countries can combat energy poverty by enhancing renewable energy and economic growth with minimal adverse environmental effects. In this paper, we present a comprehensive analysis of energy poverty, renewable energy, economic growth, carbon dioxide emissions, and urbanization (URB) in South Asian countries from 1990 to 2021, focusing on Pakistan, India, Bangladesh, and Sri Lanka. We employed econometric analysis techniques like Panel Pooled Mean Group (PMG)-Autoregressive Distributed Lag (ARDL), Fully Modified Ordinary Least Squares (FMOLS), and Dynamic Ordinary Least Squares (DOLS) to provide empirical results, as they enable panel data and control for endogeneity. The findings suggested that the fight …

Examining Links Between Somatosensation And Cognition In Children With Hemiplegic Cerebral Palsy, Kassandra M. Hewitt, Donna M. Bayliss, Belinda A. Mclean, Ashleigh L. Thornton, Jonson J. Moyle

Research outputs 2022 to 2026

Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While somatosensation may relate to cognitive functioning in CP, this relationship has not previously been investigated. This cross-sectional study examined the relationship between somatosensation and cognition in children with hemiplegic CP, and whether the pattern of brain injury, classified using an established MRI classification system, moderates this relationship. Forty-seven children (26 females) with hemiplegic CP participated (mean age = 11.0 years; SD = 3.6; range: 6–16 years). Parent questionnaires provided demographic, educational, …

Feeling Giggity: Ambiguous Emojis In Teaching And Learning Communications, Mary Kynn, Nicole Reinke, Eva Hatje

Research outputs 2022 to 2026

There is an increase in the number of digital platforms used in higher education classrooms that promote using emojis to capture students’ emotions. However, there is little evidence to suggest that interpretation of emojis is reliable in this context. This pilot project explored if emojis can reliably signify the emotions expressed by first-year university students. Students were asked to record their emotions by selecting a representative emoji and using free text to describe its meaning. A total of 72 responses were recorded in an anonymous online survey. Happy face emojis were used more frequently than emojis representing neutral or unpleasant …

Fostering Sustainable Business Performance: The Synergistic Role Of Entrepreneurial Leadership And Green Organizational Support In The Hotel Industry, Kwame Owusu Boakye, Michael Kyei-Frimpong, Aaron Makafui Ametorwo, Linda Quagraine, Richard Sam-Mensah

Research outputs 2022 to 2026

This study investigated the moderating role of green organizational support in the nexus between entrepreneurial leadership and sustainable business performance. The study adopted the explanatory research design, where data were collected from 208 employees working in star-rated hotels in Ghana and analyzed using descriptive and inferential statistics. The result revealed that entrepreneurial leadership significantly relates to sustainable social and environmental performance but not to sustainable economic performance. More so, green organizational support moderated the relationship between entrepreneurial leadership and sustainable economic and social performance but did not moderate the relationship between entrepreneurial leadership and sustainable environmental performance. Theoretical and practical …

Importance Of Strength Training To Prevent Secondary Lower Limb Musculoskeletal Injury In Military Personnel, Peter Ladlow, Russell J. Coppack, Robyn P. Cassidy, Rachel Rodgers, Robert Barker-Davies, Paul Comfort, Nicholas J. Ripley, Christopher Bramah, Colin Suffield, Debra Hayhurst, Marina De Vecchis, Samual R. Higgins, Alexander N. Bennett, Oliver O’Sullivan

Research outputs 2022 to 2026

Considerable operational and financial costs are associated with musculoskeletal injury (MSKI) across military organisations. Following an MSKI, reaching ‘medically fully deployable’ status is often contingent on meeting physical employment standards. Strength training has a critical role to play in military physical preparation, injury mitigation and guiding rehabilitation practice. Low levels of muscle strength are associated with increased MSKI risk, and previous MSKI is a leading risk factor for re-injury. When an MSKI does occur, it is essential that all attempts to mitigate the risk of secondary MSKI are met. Maximal force (muscle strength) and rapid force (rate of force development …

Influence Of Prior Alkalosis Or Acidosis On Physiological Responses During Passive Hyperthermia, Jacky Soo, Shernise Ng, Chris Abbiss, Olivier Girard, Mohammed Ihsan

Research outputs 2022 to 2026

This study manipulated the blood pH of participants to be mildly acidic or basic prior to passive hyperthermia to examine its effects on thermoregulatory and chemo-regulatory responses, including ventilatory parameters, rectal temperature (Tre) and thermal perception. Twelve healthy males attended three experimental sessions in a double-blind, randomised, counterbalanced design. Passive hyperthermia was induced by hot water immersion at 40°C following the consumption of corn starch (placebo; PLA), ammonium chloride (AC) or sodium bicarbonate (SB). Compared with PLA, SB consumption increased blood pH and HCO3⁻, whilst AC decreased both blood pH and HCO3⁻ (all P <  0.001). Specifically, minute ventilation was unchanged following SB (11.0 ± 3.7 L min⁻¹) but …

International Cardiac Advanced Life Support Course: A Cross-Sectional Descriptive Analysis, Nilufeur Mckay, Jody Ede, Jessica Stokes-Parish, Adrian Levine, Helen Walthall, Debbie Massey

Research outputs 2022 to 2026

Background: Recognising and responding to cardiac surgical deterioration requires a systematic, structured approach that encompasses monitoring, identifying and managing signs and symptoms of post-surgical complications. Cardiac Advanced Life Support (CALS) was originally developed in recognition of this educational requirement and consists of a series of protocols aimed at supporting clinicians’ recognition and response to the deteriorating cardiac surgical patient. Aim: The aim of this analysis was to evaluate participant perceptions of a CALS course using a descriptive online survey. Design: A cross-sectional analysis of post-course online survey responses assessing participant’ perceptions of the CALS course. Results: 331 surveys were returned …

Intravenous Infusion Of Nicotinamide Adenine Dinucleotide (Nad+) Versus Nicotinamide Riboside (Nr): A Retrospective Tolerability Pilot Study In A Real-World Setting, Kirsten Reyna, Greer Heinzen, Nikita Patel, Marie Ritter, Alexandra Siojo, Henry Legere, Rachele Pojednic

Research outputs 2022 to 2026

Background: Nicotinamide adenine dinucleotide (NAD⁺) is a cofactor for NAD⁺-dependent enzymes that regulate DNA repair, cellular metabolism, and immune function. Supplementation with NAD⁺ and its precursors is commonly used to prevent age-related disease and extend healthspan. Commercial clinical and wellness settings increasingly provide intravenous (IV) NAD⁺ and nicotinamide riboside (NR) despite limited evaluation of safety and effectiveness. These considerations are important, as NAD⁺ and its precursors differ in reported side effects, cellular uptake, and metabolism. This study sought to compare commercially administered NAD⁺ IV and NR IV in humans by evaluating infusion …

Numerically Evaluating The Effect Of Extrusion Angle On Material Flow And Thermal Behaviour During Additive Friction Extrusion Deposition (Afed), Numan Habib, Ferdinando Guzzomi, Ana Vafadar

Research outputs 2022 to 2026

Additive Friction Extrusion Deposition (AFED), also known as “SoftTouch”, is an emerging friction-based Additive Manufacturing (AM) technology allowing material to soften before the deposition, increasing the printing speed and reducing cost [1]. However, high power is required during the process, as excessive force is needed to extrude enough material through the printing head. This study investigates how extrusion angle and tool rotational speed affect thermal distribution and material flow in AFED to minimise power consumption. A three-dimensional computational fluid dynamics (CFD) model is proposed, and ANSYS ^® Workbench CFD code (Fluent) is used to discretise the CFD model. A User-Defined …

Perceived Realism, Place Attachment, And Residents' Support And Involvement: Towards Resident-Centric Film Tourism Development, Deborah Castro, Sangkyun Kim, S. Mostafa Rasoolimanesh, Songshan Huang

Research outputs 2022 to 2026

This study introduces the concept of perceived realism to (film) tourism studies and examines its effect in combination with place attachment on residents' support for and involvement in film tourism development. Partial least squares structural equation modelling (PLS-SEM) and fuzzy-set Qualitative Comparative Analysis (fsQCA) were applied to a sample of 401 Barcelona residents to explore both symmetrical and asymmetrical relationships among the research constructs. The PLS-SEM revealed that events-focused external realism affects residents' support for film tourism development, while narrative realism affects their involvement in film tourism development. In addition, place attachment directly affects residents' support for and involvement in …

Personal Family-Centred Care For Lgbtq+ Individuals In Acute Hospital Settings: A Scoping Review, Gideon U. Johnson, Bianca Ysabelle Esmeralda, Stephen Pearson, Beverley Ewens, Louise Rose

Research outputs 2022 to 2026

Aim: To identify and synthesise existing evidence on family-centred care for Lesbian, Gay, Bisexual, Transgender, Queer and other diverse identities (LGBTQ+) people in acute hospital settings, including hospital-based palliative care, oncology, general in-patient and intensive care. Design: A scoping review guided by the JBI methodology. Methods: Nine databases and grey literature sources were searched. Inclusion criteria focused on LGBTQ+ adults and family-related care experiences in hospital-based acute settings. After screening, qualitative, quantitative, and narrative data were extracted. Thematic analysis synthesised findings, with quantitative data narratively integrated. Data Sources: Searches were conducted across nine databases and grey literature up to April …

Sales Prediction In Omnichannel Distribution Systems Based On Consumer Behavior Using Process Mining And Arimax, Ferra Arik Tridalestari, Mustafid Mustafid, Ferry Jie, Hanung Nindito Prasetyo

Research outputs 2022 to 2026

Omnichannel distribution integrates multiple sales channels into a single management platform to enhance customer experience. However, the complexity of consumer behavior data across channels often prevents business owners from effectively analyzing and predicting sales. This study proposes a sales prediction model in omnichannel distribution systems based on consumer behavior using a collaborative approach that integrates process mining and autoregressive integrated moving average with exogenous variables (ARIMAX). Event log data from an omnichannel service provider were used to extract consumer activity patterns, which were then analyzed through process discovery algorithms to identify dominant behavioral processes. The resulting behavioral indicators served as …

Schools, Space And Atmospheres: The Value Of Student Videos In Negotiating Contested Spaces In New Urban Vertical Schools, Prue Miles, Kylie Boltin, Stuart Poyntz, Jill Willis

Research outputs 2022 to 2026

Voices of young people are essential in civic discourse about thriving futures. Yet dialogue can be complicated when the experiences of adults and young people are vastly different, for example in school spaces designed by adults in cities designed for adults. Vertical, highrise inner city schools represent this intersection. A new genre of school in Australia, vertical schools symbolise aspirations for young people and livable cities as designed by adults. This paper draws from data collected in the Thriving in Vertical Schools project to explore the importance of affective learning atmospheres for students, and the value of digital stories to …

Situating Australian Youth Work Within The Professions, John Sutcliffe

Research outputs 2022 to 2026

Youth work in Australia has moved towards greater professionalisation marked by the establishment and strengthening of state and national associations. This evolution is crucial for the development of youth work, although it has not been without its complexities. Historically, debates over the professionalisation of the field have been contested. Proponents have emphasised benefits including standardisation and increased accountability, while critics have expressed concern that bureaucratic processes could undermine the relational, practitioner-led core of youth work. This article moves beyond the ‘should we’ debate to focus on how youth work’s professional identity is evolving and how it fits within the broader …

Sugar Consumption In Aboriginal Children Explored From A Social Practice Perspective, Amy Budrikis, Angela Durey, Dan Mcaullay, Paul Ward, Hanny Calache, Thierry Ng, Roma Winmar, Linda Slack-Smith

Research outputs 2022 to 2026

Australian Aboriginal children have higher sugar intake and are disproportionately affected by sugar-related diseases such as obesity, diabetes and dental caries than non-Aboriginal children. The intention of this paper was to highlight the need for approaches that can capture the complexity of health practices without reducing them to either individual choice or structural determination. We explore sugar consumption in Aboriginal children from a social practice perspective. Here, the unit of analysis is the practice, not the individual, where the elements of a social practice (competence, materials and meanings) are integrated into its performance. We conducted qualitative research using elements of …

Sustainable Healthcare In Action: Six Practice Changes That Make A Difference, Christine Catling, Carol Crevacore, Melisa Young, Wayne Varndell, Jack Cornish, Sue Sheppard-Law, Elaine Correia Moll

Research outputs 2022 to 2026

Problem: Planetary health, linking the well-being of human populations with the stability of Earth's natural systems, is increasingly recognised as essential for all organisations. Healthcare is a major contributor to environmental harm, responsible for an estimated 4.4% of global net emissions. As a result, healthcare workers have an important role in driving sustainable, low-waste practices within clinical settings. Aim: This paper outlines six practical, evidence-informed changes that can be introduced within healthcare organisations: adopting reusable tourniquets, reducing unnecessary glove use, recycling medication blister packs, promoting reusable nappies, using reusable or compostable blueys, and reintroducing stainless steel holloware. Discussion: These examples …

Sustaining Caring Mobilities In Immobility Regimes: Adaptive Strategies Of Vietnamese Migrant (Grand)Parents In Australia, Hien Thi Nguyen, Catriona Turnbull, Loretta Baldassar

Research outputs 2022 to 2026

(Grand)parents are increasingly traveling internationally to visit and spend time with their transnational families. This mobility is essential to provide informal, unpaid care, driven by globalisation as family members relocate for study and work. However, governments in receiving countries like Australia are implementing restrictive measures, defined in the literature as ‘immobility regimes’, to control the movement of older migrants into their territories, including overseas (grand)parents. Drawing on the lived experiences of 22 Vietnamese migrants (11 (grand)parent visitors and 11 adult migrants who host their (grand)parent visitors), this paper explores the relationship between transnational mobility and institutional migration policies in the …

Systematic Literature Mapping: Integrated System Of Logistic Distribution For Island, Eka Suswaini, Mochammad Agung Wibowo, Ferry Jie

Research outputs 2022 to 2026

Purpose: The study aims to identify and compare various methods used to optimize supply chain distribution, with a focus on uncovering novel approaches. It particularly addresses the gap in logistics distribution models tailored for island environments, proposing the development of an integrated information system using genetic and memetic algorithms to handle uncertainties like weather and vessel availability. Design/methodology/approach: A Systematic Literature Mapping (SLM) approach was adopted. The K-Chart method was applied to categorize conceptual strategies and identify research gaps. A case study was also included to analyze logistical challenges in island settings, incorporating real data variables like transportation schedules and …

The Nexus Between Local Food Tourism Events And Social Sustainability: Future Prospects And Priorities, Alicia Orea-Giner, Francesc Fusté-Forné, Louise Todd, Eerang Park

Research outputs 2022 to 2026

Food has increasingly taken a central role in events and festivals, and its significance in tourism has been well documented through various social and cultural perspectives. However, our understanding and the available research evidence regarding the substantial roles, contributions, and challenges of food tourism events, particularly in relation to social sustainability, remain limited. To accurately assess the development of research on food tourism events and those through the lens of social sustainability, a bibliometric analysis was conducted on studies published from 1983 to 2025, followed by a systematic literature review. The findings reveal five evolving research themes in the field: …

What Is Resistance Exercise? A Review Of Current Uses And Potential Ways Forward, Lars H. Lohmann, José Afonso, David G. Behm, Stanislaw D. Siegel, Michael Keiner, Klaus Wirth, Anthony J. Blazevich, Eric R. Helms, Alyssa Joy Spence, Konstantin Warneke

Research outputs 2022 to 2026

The resistance exercise (RE) literature highlights the importance and impact of RE in sports performance, daily life, and clinical outcomes. While RE research dates back to the 19th century, current definitions of what constitutes RE are varied and give rise to questions about the requisites of RE. For example, some definitions refer to movements or muscle contractions against external resistance whereas others consider all repeated actions against one’s bodyweight. Taken to the limit, this could introduce confusion between RE and endurance exercise, for example. Without a clear definition, systematic reviews (with meta-analysis) discuss outcomes of studies examining the effects of …

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes At Aβ-Pet Centiloid 15, Mean Age Of 66 Years, Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey-Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph Martins, Colin L. Masters, James Doecke

Research outputs 2022 to 2026

Objective: Sporadic late-onset Alzheimer's disease (AD) is characterized by a long pre-clinical phase where amyloid-beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ-PET) and plasma Aβ42/40 become abnormal. Methods: Two high performance immunoprecipitation-mass spectrometry (IP-MS) assays (WashU/C2N and Shimadzu) were tested on samples from 1,450 participants who were diagnosed as cognitively unimpaired (CU), mild cognitive impairment (MCI), or AD-dementia across 4 international cohorts. Natural history modeling and trajectory analyses of the combined Aβ-PET …