Digital Commons Network^™

Development Of A Risk Scoring System For Predicting Post-Extraction Medication-Related Osteonecrosis Of Jaws: A Derivation And Validation Cohort Study, Ling-Ying Wei, Ching-Ming Chiu, Sang-Heng Kok, Hung-Ying Lin, Wei-Yih Chiu, Hao-Hong Chang, Shih-Jung Cheng, Jang-Jaer Lee

Journal of Dental Sciences

Background/purpose: Although risk factors for medication-related osteonecrosis of the jaw (MRONJ) are known, clinical assessment prior to dental extraction remains largely subjective. We aimed to develop and externally validate a simple clinical risk scoring system to predict post-extraction MRONJ in osteoporotic patients receiving antiresorptive therapy (ART) and support evidence-based clinical decision-making.

Materials and methods: This retrospective cohort study used a derivation cohort (N = 1,067 extractions, 2003‒2022) to develop a 5- to 16-point risk score system based on five predictors (age ≥ 75, ART duration ≥ 24 months, bisphosphonate use, drug interruption < 3 months, and extraction site). The model was validated in an independent cohort (N = 928 extractions, 2022–2024) using a pre-defined ≥12 cut-off. Performance metrics included the area under the curve (AUC), sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV).

Results: MRONJ prevalence was lower in the validation …

Prevalences Of Vitamin B12 Deficiency, Pernicious Anemia, Macrocytosis, And Hyperhomocysteinemia In 532 Serum Gastric Parietal Cell Antibody-Positive Oral Mucosal Disease Patients, Yu-Hsueh Wu, Yi-Pang Lee, Julia Yu-Fong Chang, Yi-Ping Wang, Andy Sun, Chun-Pin Chiang

Journal of Dental Sciences

Background/purpose: Our previous studies found the serum gastric parietal cell antibody (GPCA) positivity in 12.3% to 26.7% of atrophic glossitis (AG), burning mouth syndrome (BMS), and oral lichen planus (OLP) patients. This study assessed whether GPCA-positive oral mucosal disease (GPCA⁺OMD) patients (including 284 AG, 109 BMS, and 139 OLP patients) had significantly higher frequencies of microcytosis, macrocytosis, anemia, serum iron and vitamin B12 deficiencies, and hyperhomocysteinemia than healthy control subjects (HCSs) or GPCA-negative OMD (GPCAˉOMD) patients.

Materials and methods: The mean corpuscular volume, blood Hb, and serum iron, vitamin B12, homocysteine, and GPCA levels were measured and compared …

Influence Of All-On-4 Implant Angles On Stability And Crestal Bone - A Finite Element Optimization Analysis,, Jing-Jie Chen, Chen-Sheng Chen

Journal of Dental Sciences

No abstract provided.

Poly-Ε-Caprolactone/Multi-Wall Carbon Nanotube Composites As Osteoinductive Scaffolds For Alveolar Bone Regeneration,, Chien-Yang Yeh, Firdiansyah Rasyid

Journal of Dental Sciences

No abstract provided.

Comparative Effects Of Plasma Activation And Monomer Infiltration On The Surface Characteristics And Wettability Of 3d-Printed Permanent Crown Resin,, Pyi Phyo Win, Szu-Yu Lai

Journal of Dental Sciences

No abstract provided.

Optogenetic Control Of Odontoblastic Differentiation In Dental Pulp Stem Cells (Dpsc), Francesco Torelli

Journal of Dental Sciences

No abstract provided.

Craniofacial And Dental Arch Morphological Changes In Pediatric Obstructive Sleep Apnea Syndrome Following Rapid Maxillary Expansion, Yu-Hao Liu, Yu-Shu Huang, Yi-Jing Hwang

Journal of Dental Sciences

No abstract provided.

Integrating Image Processing And Deep Learning Framework For Automatic Supernumerary Tooth Detection On Occlusal Radiographs, Jui-An Fu, Chia-Lin Hsu

Journal of Dental Sciences

No abstract provided.

Deciphering Novel Targets In Salivary Gland Pleomorphic Adenoma By Integrating Plasma Proteomics And Parotid Transcriptomics Analyses, Yuchen Fan, Suning Mao

Journal of Dental Sciences

No abstract provided.

Mesenchymal Stem Cells Derived From Gingiva Normoxic Or Hypoxic-Preconditioning Allogenous Transplantation Affect Orthodontic Tooth Movement In Vivo, Alexander Patera Nugraha, Guang Hong

Journal of Dental Sciences

No abstract provided.

Risk Of Pneumonia And Mortality After Routine Dental Scaling In Patients With Moderate-To-Severe Cerebral Palsy: A Nationwide Cohort Study, Li-Wei Ou-Yang, Ya-Ting Chang

Journal of Dental Sciences

No abstract provided.

Strategy Of Allying General Dentistry Staffs Into Pre-Anesthetic Dental Assessment Reduces Perioperative Dental Injury Risk During General Anesthesia, Cheng Lu, Mei-Chun Chen

Journal of Dental Sciences

No abstract provided.

Oral Health-Related Quality Of Life And Diabetes Outcomes: Evidence From A Nationally Representative U.S. Sample, Hsueh-Fen Chen, Jou-Hsun Lee

Journal of Dental Sciences

No abstract provided.

Osteoclast-Derived Exosomes Promote Medication-Related Osteonecrosis Of The Jaw By Delivering Glycorna To Disrupt The Blood–Lymphatic Vascular Network, Jiankang Zhang, Junming Tao

Journal of Dental Sciences

No abstract provided.

Vanadium-Functionalized Methyl Methacrylate-Based Primer Enhances Self-Curing And Bonding Of Resin Cement To Polyetheretherketone Restorations, Takeru Kondo, Jun Sato

Journal of Dental Sciences

No abstract provided.

A Visualized Ai-Assisted Framework For Pre-Surgical Evaluation Of Implant Pathways On Periapical Radiographs, Yuan-Jin Lin, Chiung-An Chen

Journal of Dental Sciences

No abstract provided.

Comparative In Vivo Study Of 3d-Printed Composite Bioceramic Scaffolds Fabricated By Distinct Pre-Processing Methods, Yu-Ting Li, Ju-Hsuan Yang

Journal of Dental Sciences

No abstract provided.

Fluvastatin Enhances Healing Of Medication−Related Osteonecrosis Of The Jaw (Mronj) Via Macrophage Polarization In A Rat Mronj−Like Model, Moa Tazaki, Koma Sanda

Journal of Dental Sciences

No abstract provided.

Retrospective Accuracy Comparison Of Marker-Based And Marker-Free Registrations Using Dynamic Implant Navigation, Zhiyi Zhu, Shikai Zhao

Journal of Dental Sciences

No abstract provided.

Synergistic Effect Of Combined Cisplatin And Rosmarinic Acid On Apoptosis And Migration Of Head And Neck Cancer Cell Lines, Suppanut Jongjitaree, Paopanga Kokilakanit

Journal of Dental Sciences

No abstract provided.

Effect Of Horizontal Dimensional Malocclusions On Smile Changes In Frontal, Lateral, And Oblique Views Before And After Orthodontic Treatment, Johnson Hsin-Chung Cheng, Sarah Jia-Min Lin

Journal of Dental Sciences

No abstract provided.

Artificial Intelligence-Powered Chatbots’ Responses To Orthodontic Questions From The Dentistry Specialization Examination: Accuracy And Source Evaluation, Berrak Çakmak, Tevhide Sökmen, Burcu Balos‚ Tuncer

Journal of Dental Sciences

No abstract provided.

The Utility Of 3d Nanostructured Polyglycolic Acid Fibers For Novel Bone Regenerative Medicine, Itsuki Hayashi, Sayaka Nakamura-Yamada

Journal of Dental Sciences

No abstract provided.

Dual Effects Of 1Α,25-Dihydroxyvitamin D3 On Inflammation And Osteogenic Differentiation In Lipopolysaccharide-Stimulated Dental Pulp Stem Cells, Seong Eun Song, Giyoung Yun

Journal of Dental Sciences

No abstract provided.

A Novel Method For The Precise Second Mesiobuccal Canal Orifice Location: A Combined Strategy For Enhanced Clinical Practice, Yuhan Wang, Lingyun Li,

Journal of Dental Sciences

No abstract provided.

A Scientometric Study On Research Trends And Characteristics Of Diabetes-Associated Periodontal Disease, Man Yang, Wenxiao Shi, Yan Xiong, Mengjie Chen, Linjun Shi, Huiwen Chen

Journal of Dental Sciences

Background/purpose: Substantial evidence demonstrates that diabetes is associated with periodontal disease. The purpose of this study was to analyze the scientometric characteristics and research trends of diabetes-associated periodontal disease (DAPD).

Materials and methods: All the papers on DAPD were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2019 and after 2019 in the analysis of research trends.

Results: There were 2466 papers on DAPD, with total citations of 73,553 and the h index of 120. The trend of clinical investigations has highlighted periodontal examination, bone development, micro-computed tomography, tooth brushing, cardiovascular …

Sleep Restriction Exacerbates Pulpal Inflammation And Impairs Tissue Repair Following Dental Pulp Capping: An In Vivo Animal Study, Siqi Huang, Qian Wang, Ziyu Chen, Guomiao Zhang, Ying Zheng

Journal of Dental Sciences

As a fundamental physiological process, sleep is essential for maintaining systemic homeostasis. Although sleep restriction (SR) has been shown to trigger a systemic inflammatory response, its specific impact on local pulpal inflammation remains poorly understood. In this preliminary study, we investigated the effects of SR on the inflammatory response and reparative capacity of dental pulp in a rat model. Immunohistochemistry and western blotting revealed that, even in intact pulp tissue, SR upregulated the expression of interleukin-6, increased the infiltration of neutrophils, and activated the nuclear factor-kappa B signaling pathway. Subsequent investigations demonstrated that following dental pulp capping, SR provoked an …

Socket Regeneration Using A Composite Regenerative Matrix: A Simplified Clinical Workflow With A 5-Year Follow-Up, Chi-Shan Tseng, Ming-Ko Li, Cheng-Chia Yu

Journal of Dental Sciences

Alveolar ridge remodeling following tooth extraction remains a clinical challenge in implant dentistry, particularly in the esthetic zone where dimensional stability of hard and soft tissues is critical for subsequent implant placement. This short communication describes a simplified clinical workflow for socket regeneration using a composite regenerative matrix (CRM) composed of concentrated growth factor (CGF), autologous fibrinogen glue (AFG), and freeze-dried bone allograft (FDBA). The technique was applied following atraumatic extraction in a single maxillary esthetic-zone case. Clinical and radiographic observations were documented for up to 5 years. Healing was uneventful, and cone-beam computed tomography performed at 3 months demonstrated …

Negative Pulp Sensibility Responses Do Not Necessarily Indicate Pulp Necrosis In Teeth Associated With Cystic Or Cyst-Like Lesions, Le Lu, Xiang Zhang, Ya Shen, He Liu

Journal of Dental Sciences

No abstract provided.

The Story Of A Taiwanese Female Student Studying Dentistry In Japan During The Japanese Colonial Period: An Oral History By Dr. Yueh-E Wu, Feng-Chou Cheng, Mei-Huei Li, Chien-Chi Chu, Chun-Pin Chiang

Journal of Dental Sciences

No abstract provided.