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Endovascular Thrombectomy For Acute Ischemic Stroke Among Stroke Patients In Jeddah, Saudi Arabia: A Retrospective Cohort Study (2024) Detailing Dual Center Experience, Abdullah M Alkutbi, Omar Abdulhamidayoub, Fawaz Mosaedalshareef, Mohammed M Alwadi, Rawan I Alqurashi, Rayan I Almaghrabi, Naif F Alharbi, Omar M Alhazmi, Ziad H Alzabidi, Nagham S Alsolaimani, Saher F Alqarni Jan 2026

Endovascular Thrombectomy For Acute Ischemic Stroke Among Stroke Patients In Jeddah, Saudi Arabia: A Retrospective Cohort Study (2024) Detailing Dual Center Experience, Abdullah M Alkutbi, Omar Abdulhamidayoub, Fawaz Mosaedalshareef, Mohammed M Alwadi, Rawan I Alqurashi, Rayan I Almaghrabi, Naif F Alharbi, Omar M Alhazmi, Ziad H Alzabidi, Nagham S Alsolaimani, Saher F Alqarni

Saudi Medical Journal

Background: Te evaluate the outcomes of Endovascular thrombectomy (EVT) -treated AIS patients in Jeddah, Saudi Arabia, and explores predictors of functional recovery. Endovascular thrombectomy (EVT) is the standard of care for acute ischemic stroke (AIS), though patient outcomes can vary based on regional and clinical factors. Method: A retrospective cohort study was conducted using medical records from King Abdulaziz University Hospital (KAUH) and King Fahad Hospital Jeddah (KFHJ), including AIS patients treated with EVT between January 2020 and July 2024. Neurological status was assessed using the NIH Stroke Scale (NIHSS), and clinical outcomes were evaluated with the modified Rankin Scale …


Gender Differences In Sociodemographic And Clinical Characteristics Of Methamphetamine Use In Saudi Arabia, Halima M. Adam, Mohamed Abouzed, Ahmed H. Aljadani, Benayan B. Alrasheedy, Muath A. Alarfaj, Salwa R. Alshammari, Mohamed S. Almuqahwi Jan 2026

Gender Differences In Sociodemographic And Clinical Characteristics Of Methamphetamine Use In Saudi Arabia, Halima M. Adam, Mohamed Abouzed, Ahmed H. Aljadani, Benayan B. Alrasheedy, Muath A. Alarfaj, Salwa R. Alshammari, Mohamed S. Almuqahwi

Saudi Medical Journal

Objectives: To explore gender-related variations in sociodemographic factors, clinical presentations, and psychosocial characteristics among methamphetamine users in Saudi Arabia. Methods: A retrospective cross-sectional study was conducted using the electronic health records of 1,181 patients (91% male, 9% female) treated at multiple Erada Mental and Addiction Centers across Saudi Arabia (2020–2024). Data on sociodemographic characteristics, methamphetamine use patterns, psychiatric comorbidities, and psychosocial functioning were collected and analyzed using validated tools, including the Addiction Severity Index, Beck Depression and Anxiety Inventory, and Quality of Life Scale. Results: Female participants were younger than males (mean age 25.3 vs 28.5 years; p < 0.001) and initiated methamphetamine at a later age (21.4 vs 19.2 years; p < 0.001). Females had greater proportion of daily use (65.4% vs. 60%, p = 0.035) but consumed smaller amounts per day (1.5 vs. 1.8 g, p = 0.041). They also exhibited higher rates of psychiatric comorbidities, including depression (50% vs. 30.0%, p < 0.001) and anxiety (40% vs. 20%, p < 0.001), and reported more severe psychosocial impairments, including lower quality of life (54.8 vs. 62.4, p < 0.001), higher unemployment rates (59.8% vs. 30%, p < 0.001), and more family conflicts (65.4% vs. 50%, p < 0.001). In contrast, Legal issues were more common among males (40% vs. 29.9%, p = 0.002). Conclusions: Female methamphetamine users demonstrate greater vulnerability with earlier onset, more psychiatric comorbidities, and worse psychosocial outcomes. Targeted interventions are needed for female methamphetamine users in Saudi Arabia.


Invasive Methicillin-Susceptible And Methicillin-Resistant Staphylococcus Aureus Infections In The Pediatric Population: Prevalence And Management Outcomes, Khalifa M. Binkhamis, Ibrahim A. Alhezam, Hassan A. Alabdullatif, Othman M. Alabdullah, Omar Y. Alkadhi, Nawaf M. Alrefaei, Abdullah S. Almayah, Fatema A. Juma, Sarah S. Alangari Jan 2026

Invasive Methicillin-Susceptible And Methicillin-Resistant Staphylococcus Aureus Infections In The Pediatric Population: Prevalence And Management Outcomes, Khalifa M. Binkhamis, Ibrahim A. Alhezam, Hassan A. Alabdullatif, Othman M. Alabdullah, Omar Y. Alkadhi, Nawaf M. Alrefaei, Abdullah S. Almayah, Fatema A. Juma, Sarah S. Alangari

Saudi Medical Journal

Objectives: Infections by invasive methicillin-resistant Staphylococcus aureus (MRSA) are associated with higher morbidity and mortality compared to methicillin-susceptible Staphylococcus aureus (MSSA) infections, and have increased significantly in both healthy children and children with chronic illnesses. In our study we aimed to estimate the prevalence of invasive MSSA and MRSA among invasive Staphylococcus aureus (S. aureus ) infections in the pediatric population and measure the association between management outcomes and methicillin resistance in these infections. Methods: We conducted an observational, analytical, retrospective cross-sectional, chart-review study of pediatric patients (aged ≤16 years) admitted to King Khalid University Hospital in Riyadh, Saudi Arabia …


Medication Errors Reporting And Analysis: A Comparative Study For Advancing Medication Safety Practices In Ministry Of Health Hospitals In Saudi Arabia, Saleh A. Alghamdi Jan 2026

Medication Errors Reporting And Analysis: A Comparative Study For Advancing Medication Safety Practices In Ministry Of Health Hospitals In Saudi Arabia, Saleh A. Alghamdi

Saudi Medical Journal

Objectives: To analyze and compare these stages, types, frequency, causes, and corrective actions related to medication errors (MEs) reported in Ministry of Health (MOH) hospitals in Saudi Arabia, and thereby enhance medication safety through data driven decisions. Methods: A retrospective cross-sectional study was conducted using ME reports submitted to the Saudi MOH national reporting system from January 2023 to December 2024.Data were collected from nine hospitals, covering medication involved, reporting personnel, level of harm and corrective actions. A novel stratification framework (NSF) was used to visualize emerging risks and protective trends. Statistical analyses were conducted using relative risk (RR), risk …


Sphingosine-1-Phosphate Regulation To Alleviate Sickle Cell Disease Severity: A Promising Therapeutic Approach, Shahanas Chathoth Jan 2026

Sphingosine-1-Phosphate Regulation To Alleviate Sickle Cell Disease Severity: A Promising Therapeutic Approach, Shahanas Chathoth

Saudi Medical Journal

Abstract Sickle cell disease (SCD) is a genetic disorder that affects millions of individuals worldwide. Chronic anemia, hemolysis and vasculopathy are the most common symptoms that arise from hemoglobin (Hb) polymerization, which is the primary event of SCD. The above process can lead to erythrocyte sickling. Therapeutic options for SCD remain limited, and novel therapies are still being evaluated for their effectiveness in particular populations. Sphingosine-1-phosphate (S1P), a significant bioactive sphingolipid, acts as a potent signal mediator, modulating several cellular functions. The potential role of erythrocyte-S1P in enhancing SCD severity has been previously reported by multiple studies. Therefore, the present …


From Text To Test: Pre-Lecture Reading Boosts Medical Students’ Comprehension And Retention, Hamad A. Alfahaad, Mohammed Y. Alasmary, Emad M. Masuadi, Henk G. Schmidt Jan 2026

From Text To Test: Pre-Lecture Reading Boosts Medical Students’ Comprehension And Retention, Hamad A. Alfahaad, Mohammed Y. Alasmary, Emad M. Masuadi, Henk G. Schmidt

Saudi Medical Journal

Objective: Medical students frequently attend lectures without prior review of the related literature when preparing for examinations. It raises the question of whether studying the material in advance could enhance their learning outcomes during lectures. Methods: A total of 102 medical students from a Saudi Arabian university took part in this research. Participants were assigned to one of 2 cohorts: one read a 4-page passage before a 15-minute lecture, while the other attended the lecture before reading the passage. Knowledge acquisition was measured using a test that assessed their ability to recall concepts administered 3 times—prior to the session, post …


National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash Jan 2026

National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash

Saudi Medical Journal

Objectives: To develop an evidence-based clinical guideline for the prevention and management of cardiovascular diseases (CVDs) in Saudi Arabia, tailored to local epidemiology and healthcare needs. Methods: A multidisciplinary task force comprising cardiologists, public health specialists, and epidemiologists from different healthcare sectors in Saudi Arabia developed the guideline. Evidence synthesis was based on a comprehensive literature review and adaptation of international guidelines, particularly the 2021 European Society of Cardiology recommendations, contextualized to the Saudi setting. Results: The guideline provides recommendations for both primary and secondary CVD prevention. Primary prevention emphasizes risk assessment incorporating genetic, lifestyle, and clinical factors, as well …


Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag Jan 2026

Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag

Saudi Medical Journal

No abstract provided.


Required Learning, Voluntary Service: A Critical Look At Mandatory Cle And Pro Bono Options, Rima Sirota Jan 2026

Required Learning, Voluntary Service: A Critical Look At Mandatory Cle And Pro Bono Options, Rima Sirota

Georgetown Law Faculty Publications and Other Works

This chapter critically examines the intersection of mandatory continuing legal education (MCLE) and pro bono service in the United States, focusing on the growing practice of awarding MCLE credits for pro bono work. It argues that MCLE, widely justified as promoting lawyer competence, rests on a striking lack of empirical support and is structured in ways that undermine effective professional learning. A pro bono option for earning MCLE credit, introduced as an incentive to expand access to justice, has similarly failed to demonstrate measurable impacts on pro bono participation. Nonetheless, the pro bono option holds untapped potential because, if properly …


Comparing Strength Testing Measures And The Association Of Strength And Body Composition In Young Children, Abigayle R. Spong Jan 2026

Comparing Strength Testing Measures And The Association Of Strength And Body Composition In Young Children, Abigayle R. Spong

Theses and Dissertations--Kinesiology and Health Promotion

Muscle strength is an important component of physical fitness; however, measuring it with isokinetic dynamometry (IKD) is expensive and requires dedicated space. Handheld dynamometry (HHD) provides a practical alternative for field and clinical settings. Thus, the purpose of this study was to compare peak knee flexion and extension torque measured by IKD and HHD in 37 children (ages 5-11 years) and examine relationships with body composition. Participants completed a RAMPing protocol at 90o knee flexion consisting of two warm-up contractions at 50% and 75% effort followed by three maximal voluntary isometric contractions. Body composition was assessed via DXA scans. …


Perceptions Of Sport Psychology Efforts And Access In Women's Wheelchair Basketball, Lindsay C. Cohen Jan 2026

Perceptions Of Sport Psychology Efforts And Access In Women's Wheelchair Basketball, Lindsay C. Cohen

Theses and Dissertations--Kinesiology and Health Promotion

As the field of sport psychology grows, services and training programs must evolve to properly serve the evolution of athletes seeking care. This could mean discovering new measures, testing different types of interventions, or developing programs that can better accommodate specific populations that are looking for sport psychology services. One such population is para athletes, and although they have expressed interest in learning more about the field of sport psychology and how to implement mental skills efficiently, athletes have reported a lack of access to sport psychology services and sport psychology consultants (SPCs) (Dieffenbach et al., 2009). The purpose of …


Biomechanical Effects Of Exercise-Based Interventions In Chronic Nonspecific Low Back Pain: A Systematic Review And Meta-Analysis, Lara De Vecchi Machado Jan 2026

Biomechanical Effects Of Exercise-Based Interventions In Chronic Nonspecific Low Back Pain: A Systematic Review And Meta-Analysis, Lara De Vecchi Machado

Theses and Dissertations--Kinesiology and Health Promotion

Chronic nonspecific low back pain (CNLBP) is the leading cause of years lived with disability worldwide and represents a complex, multifactorial, and heterogeneous condition. It is characterized by substantial interindividual variability in muscle activation patterns, lumbo-pelvic coordination, and movement strategies. Although exercise is widely recommended as a first-line intervention and its clinical benefits are well established, the biomechanical mechanisms underlying functional improvement remain fragmented in the literature and are rarely synthesized quantitatively.

This dissertation conducted a systematic review with meta-analysis to investigate the biomechanical effects of exercise-based interventions in individuals with CNLBP. A total of 39 studies were included and …


International Law, The Courts, And The Political Branches Of Singapore: Painting A Complete Picture, Benjamin Joshua Ong Jan 2026

International Law, The Courts, And The Political Branches Of Singapore: Painting A Complete Picture, Benjamin Joshua Ong

Research Collection Yong Pung How School Of Law

In line with Singapore's vision of the separation of powers, the courts' duty is primarily to give effect to domestic law; the political branches take the lead in engaging with international law. A study of Singapore's interface with international law would therefore be incomplete were it to consider only the courts' role and not the political branches' model of international law as primarily a guarantor of Singapore's sovereignty and standing as a participant on the international stage. The political branches have been circumspect in engaging with international law in other areas, such as human rights, preferring a specifically Singaporean vision …


Planning A Clinical Practice Guideline Revision For A Core Set Of Outcome Measures In Adults Undergoing Neurologic Physical Therapy, Part 2: Determining Stakeholders' Uptake And Recommendations, Jane E. Sullivan, Kristen Potter, Marghuretta D. Bland, Elizabeth Anderl, Wendy Romney, Zeynep Gulen Erkoc, Jennifer Moore Jan 2026

Planning A Clinical Practice Guideline Revision For A Core Set Of Outcome Measures In Adults Undergoing Neurologic Physical Therapy, Part 2: Determining Stakeholders' Uptake And Recommendations, Jane E. Sullivan, Kristen Potter, Marghuretta D. Bland, Elizabeth Anderl, Wendy Romney, Zeynep Gulen Erkoc, Jennifer Moore

Physical Therapy Faculty Publications

Objective: To determine the uptake and recommendations for revision of the 2018 Clinical Practice Guideline (CPG): Core Set Outcome Measures for Adults with Neurologic Conditions Undergoing Rehabilitation.

Design: Online Survey

Setting: Online with participants from multiple settings.

Participants: Licensed physical therapists (PT) or physical therapist assistants (PTA) or a non-PT supervisor of PTs and/or PTAs.

Interventions: N/A.

Main Outcome Measures:  An online survey was developed to determine respondents' knowledge, perceived benefits, challenges, gaps, and modifications made to the 2018 CPG as well as to ascertain respondents' recommendations for the CPG revision. Data were analyzed descriptively by respondent role (clinician, educator/researcher, …


The Relationship Between Acne Vulgaris And Insulin Resistance, Nora Moawad Erian, Nora Mohamed Darwish, Eman Saber Elhennawy, Fatma Faisal El Dakrory Jan 2026

The Relationship Between Acne Vulgaris And Insulin Resistance, Nora Moawad Erian, Nora Mohamed Darwish, Eman Saber Elhennawy, Fatma Faisal El Dakrory

Mansoura Medical Journal

Background Some have hypothesized that resistance to insulin, a condition in which cells become less responsive to insulin, contributes to the development and worsening of acne vulgaris. The study's primary objective was to identify any associations among resistance to insulin and acne vulgaris severity. Methods Forty patients (range: 18–40 years old) with acne vulgaris and forty healthy controls (range: 18–40 years old, sex: X), were included in this case control study. Height as well as weight were the anthropometric metrics. To determine how bad acne is, doctors utilize the Global Acne Grading System. Laboratory testing for insulin resistance was conducted …


Predictors And Outcome Of Sepsis And Septic Shock Induced Acute Kidney Injury In Diabetic Patients: A Prospective Observational Study, Shrouk Essam, Rehab Shaheen Bahram Shaheen, Rasha Mahmoud Prof., Adel I. Abdelsalam Jan 2026

Predictors And Outcome Of Sepsis And Septic Shock Induced Acute Kidney Injury In Diabetic Patients: A Prospective Observational Study, Shrouk Essam, Rehab Shaheen Bahram Shaheen, Rasha Mahmoud Prof., Adel I. Abdelsalam

Mansoura Medical Journal

Background: One characteristic of sepsis is the dysregulation of the host's reaction to infection, which can result in potentially fatal organ failure.This work aimed to assess predictors and outcome of sepsis and septic shock induced acute kidney injury (AKI) in diabetic patients. Methods: This prospective observational study included diabetic patients aged over 18 years who were admitted with sepsis or septic shock in the Medical Critical Care Unit of the Specialized Medical Hospital, Mansoura University. All patients were divided into 2 groups:AKI Group (N=74): diagnosed with AKI and No AKI Group (N=26): did not develop AKI. Results: Analysis of risk …


Study Of The Relationship Between Insulin Resistance And Osteoporosis In Type 2 Diabetes Mellitus And Diabetic Nephropathy Elderly Patients, Mohamed Zakarya Nooh, Alaa Abdelsalam Dawood, Bassant Samy Hamed Hafez, Moustafa Bakrey Hamed Ata Jan 2026

Study Of The Relationship Between Insulin Resistance And Osteoporosis In Type 2 Diabetes Mellitus And Diabetic Nephropathy Elderly Patients, Mohamed Zakarya Nooh, Alaa Abdelsalam Dawood, Bassant Samy Hamed Hafez, Moustafa Bakrey Hamed Ata

Mansoura Medical Journal

Background Type 2 diabetes mellitus and diabetic kidney disease play a major role in bone deterioration and increased fracture risk because they influence both insulin sensitivity and bone metabolism. Objective The purpose of this study was to investigate the connection between osteoporosis and insulin resistance in older individuals with type 2 diabetes and diabetic kidney disease (DKD). Methods: A total of 105 participants were enrolled in the study and divided equally into three groups: 35 diabetic patients with albuminuria, 35 diabetic patients without albuminuria, and 35 age- and gender-matched healthy controls. The study was conducted at the Endocrinology & DM …


Evaluation Of Neutrophils To Albumin Ratio (Nar) And C-Reactive Protein To Albumin Ratio (Car) As Markers Of Disease Activity In Patients With Ulcerative Colitis, Doaa Salah Abd-El-Fattah, Mohamed Abd El-Maksoud, Salwa M. Abo El-Khair, Ahmed El-Eraky, Amany Hasson Jan 2026

Evaluation Of Neutrophils To Albumin Ratio (Nar) And C-Reactive Protein To Albumin Ratio (Car) As Markers Of Disease Activity In Patients With Ulcerative Colitis, Doaa Salah Abd-El-Fattah, Mohamed Abd El-Maksoud, Salwa M. Abo El-Khair, Ahmed El-Eraky, Amany Hasson

Mansoura Medical Journal

Background Ulcerative colitis (UC) is considered an extensive disease due to the risks of proximal extension, malignant transformation, disability and impaired life quality. This study aimed to explore the role of Neutrophils to Albumin Ratio (NAR) and C - reactive protein to Albumin Ratio (CAR) in evaluation of disease activity in patients with UC. Methods This cross-sectional study included 227subjects classified into two groups; group (I) included 126patients suffering from ulcerative colitis and group (II) included 101 healthy individuals with normal basic laboratory tests matched for age and sex. Estimating disease activity and severity clinically was according to Truelove criteria. …


Impact Of Admission Hyperglycemia On In-Hospital Arrhythmia In Medical Critical Illness, Ebrahim Elsayed Tawfik, Afaf Abdel Hafez, Tarek El-Sayed Gouda, Rehab Shaheen Bahram Shaheen Jan 2026

Impact Of Admission Hyperglycemia On In-Hospital Arrhythmia In Medical Critical Illness, Ebrahim Elsayed Tawfik, Afaf Abdel Hafez, Tarek El-Sayed Gouda, Rehab Shaheen Bahram Shaheen

Mansoura Medical Journal

Background Admission hyperglycemia is frequently encountered in critically ill patients, even in the absence of pre-existing diabetes. Acute stress hyperglycemia triggers autonomic activation, oxidative stress, and electrophysiological disturbances that may predispose to cardiac arrhythmias. Aim of work The present study aimed to explore the frequency and type of arrhythmic events among critically ill patients with admission hyperglycemia in medical intensive care units (MICU). Methods: A prospective study was conducted on 354 critically ill ICU patients . They were divided into group A with admission hyperglycemia (>180 mg/dL) and group B with admission normoglycemia (≤180 mg/dL). All patients were subjected …


Evaluation Of The Frequency Of Subclinical Peripheral Neuropathy Among Children And Adolescents With Type 1 Diabetes Mellitus Using Nerve Conduction Studies, Hadeer Ashraf Abdulwahab, Ann A. Abdelkader, Nanees Salem, Bothina Hasaneen Jan 2026

Evaluation Of The Frequency Of Subclinical Peripheral Neuropathy Among Children And Adolescents With Type 1 Diabetes Mellitus Using Nerve Conduction Studies, Hadeer Ashraf Abdulwahab, Ann A. Abdelkader, Nanees Salem, Bothina Hasaneen

Mansoura Medical Journal

Background: The long-term vascular complications of diabetes mellitus (DM) include nephropathy, retinopathy, neuropathy, and macrovascular diseases, so the aim of this study was to evaluate the frequency of subclinical peripheral neuropathy among children and adolescents with Type 1 DM using nerve conduction studies (NCSs) in relation to diabetesrelated clinical and metabolic parameters. Methods: This cross-sectional study was conducted on 50 children and adolescents with T1D. The patients were divided into 2 groups, symptomatic group who had symptoms or signs of diabetic sensorimotor polyneuropathy (DSPN) and asymptomatic group who had no signs or symptoms of polyneuropathy. NCSs were conducted and sensory …


Readmission And Reoperation Following Transurethral Incision Of The Prostate For Benign Prostatic Obstruction: A 20-Year Retrospective Review And Analysis, Amr Wael Yehia, Mohamed Hegazy, Ahmed Refat Elnahas, Ahmed Mohamed Elshal Jan 2026

Readmission And Reoperation Following Transurethral Incision Of The Prostate For Benign Prostatic Obstruction: A 20-Year Retrospective Review And Analysis, Amr Wael Yehia, Mohamed Hegazy, Ahmed Refat Elnahas, Ahmed Mohamed Elshal

Mansoura Medical Journal

Introduction: Transurethral Incision of the Prostate (TUIP) is a recognized surgical treatment for benign prostatic obstruction (BPO), particularly in patients with smaller glands. While valued for its minimal invasiveness, it is associated with higher medium-term reoperation rates. This study analyzes a 20-year institutional experience to define the rate, timing, causes, and predictors of readmission and reoperation after TUIP. Methods: A retrospective review of 557 patients who underwent TUIP for BPO was conducted. Data collected included demographics, comorbidities, perioperative details and complications graded by the Clavien-Dindo system. Univariate and multivariate logistic regression analyses identified predictors of readmission and reoperation if present. …


Assessment Of Serum Level Of Il-38 In Patients With Non-Segmental Vitiligo And Its Relation To Disease Severity, Zahraa Jafar Ahmed Altaitoon, Al-Shahat Farag Ahmed Sharaf, Hamdy Fouad A. Marzo, Mohammed Samir Sultan Jan 2026

Assessment Of Serum Level Of Il-38 In Patients With Non-Segmental Vitiligo And Its Relation To Disease Severity, Zahraa Jafar Ahmed Altaitoon, Al-Shahat Farag Ahmed Sharaf, Hamdy Fouad A. Marzo, Mohammed Samir Sultan

Mansoura Medical Journal

Background: Vitiligo is a common autoimmune disorder (AID) characterized by extensive loss of melanocytes, causing depigmented skin patches. Interleukin-38 (IL- 38), an anti-inflammatory cytokine, has been linked to several autoimmune conditions, but its involvement in vitiligo hasn’t been confirmed. Aim: To measure serum IL-38 levels in patients with non-segmental vitiligo (NSV) and explores how these levels relate to disease severity and activity. Methods: We conducted a cross-sectional case-control study that included 40 patients with non-segmental vitiligo and 40 healthy individuals matched for age, sex, and BMI. Assessment of disease severity and activity was conducted by using the Vitiligo Area Scoring …


Management Of Seroma After Posterior Lumbar Spine Decompression, Ayman Mohamed Basha, Ahmed Anas Zahra Jan 2026

Management Of Seroma After Posterior Lumbar Spine Decompression, Ayman Mohamed Basha, Ahmed Anas Zahra

Mansoura Medical Journal

Background: Postoperative seroma formation represents a significant complication following posterior lumbar spine decompression (PLSD) that can compress neural structures, cause radiculopathy, and serve as potential infection sources. This study evaluated the clinical characteristics and therapeutic approaches for seroma formation after posterior lumbar decompression procedures.

Methods: An observational study was conducted on 140 patients aged 18 years and older who underwent elective PLSD. Patients were systematically evaluated at predetermined intervals using clinical examination and diagnostic imaging when seroma was suspected. Management protocols were stratified according to seroma size, symptom severity, and clinical progression, ranging from conservative compression dressings to percutaneous aspiration …


Role Of 16s Rrna Gene And Activin-A In Detection Of Neonatal Sepsis, Reem Gomaa, Walaa Othman Elshabrawy, Nada Mohsen, Mohamed Mofreh Jan 2026

Role Of 16s Rrna Gene And Activin-A In Detection Of Neonatal Sepsis, Reem Gomaa, Walaa Othman Elshabrawy, Nada Mohsen, Mohamed Mofreh

Mansoura Medical Journal

Objective: A bloodstream infection in a newborn less than 28 days is referred to as neonatal sepsis (NS). A novel quick and sensitive markers are required for the early detection of bacterial infections in neonates with sepsis, even if blood culture is a great way to diagnose sepsis because the results are delayed. This study was done to estimate the value of activin-A and molecular method (16S rRNA gene) by PCR as new methods for diagnosis of neonatal sepsis.

Methods: Fifity neonates came to the Mansoura University Children Hospital (MUCH) divided into two Groups: Group І (Sepsis group) …


Comparative Study Between Cervical Disc Arthroplasty And Anterior Cervical Discectomy And Fusion, Samer Samy, Ayman Mohamed Basha Jan 2026

Comparative Study Between Cervical Disc Arthroplasty And Anterior Cervical Discectomy And Fusion, Samer Samy, Ayman Mohamed Basha

Mansoura Medical Journal

Background: Cervical disc arthroplasty (CDA) has emerged as an alternative to anterior cervical discectomy and fusion (ACDF), aiming to preserve segmental motion and reduce adjacent segment disease (ASD). However, evidence regarding its superiority remains controversial. This study was designed to relate ACDF and CDA following anterior cervical discectomy with respect to safety, efficacy, and impact on patient lifestyle.

Methods: This retrospective comparative study included 36 patients who underwent anterior cervical discectomy between August 2021 and September 2024. Twenty patients underwent ACDF (Group A), and sixteen patients underwent CDA (Group B). Clinical outcomes were assessed using the Visual Analogue Scale (VAS) …


Could Peri-Coronary Fat Thickness Predict Severity Of Pulmonary Covid 19 And Post Covid-19 Pulmonary Scarring?, Basma A El-Ged, Dalia Fahmy, Mohamed Hamoda, Mohamed Tohlob, Heba M Abou El-Atta Jan 2026

Could Peri-Coronary Fat Thickness Predict Severity Of Pulmonary Covid 19 And Post Covid-19 Pulmonary Scarring?, Basma A El-Ged, Dalia Fahmy, Mohamed Hamoda, Mohamed Tohlob, Heba M Abou El-Atta

Mansoura Medical Journal

Objective: to study the correlation between peri-coronary fat thickness (PCFT) and clinical disease severity in patients with proved COVID-19, as well as post COVID-19 scarring.

Patients and methods: This retrospective comparative study included 202 patients with pulmonary COVID-19 who were referred for Chest High Resolution Computed Tomography (HRCT). Patients were further classified into Group A who had non-severe covid 19 disease and group B who had severe and critical disease according to WHO criteria. CT severity score (CSS), Total fibrosis score (TFS) and peri coronary fat thickness (PCFT) were evaluated and compared for both groups in the CT scans of …


Epidemiology Of Closed Ruptured Tendoachilles, Hesham Mousad Alsakaan, Wael Mansour Wafa, Mohieb Sayed Ahmed, Ahmed El Sayed Magdy Elhawary Jan 2026

Epidemiology Of Closed Ruptured Tendoachilles, Hesham Mousad Alsakaan, Wael Mansour Wafa, Mohieb Sayed Ahmed, Ahmed El Sayed Magdy Elhawary

Mansoura Medical Journal

Background: To restore tendon function and avoid long-term impairment, early diagnosis and adequate treatment are crucial. The purpose of this study was to ascertain the incidence pattern of ATR and to pinpoint possible variables related to presentation and management approach.

Aim  identifying potential risk factors either patient or environmental related and to assess the incidence rate of ATR

Patients and Methods: This retrospective cross-sectional study was performed on 87 achilles tendon rupture patients. All the patients were subjected to full medical history taking. Clinical examination was performed including thompson test and Matles test and radiological investigations.

Results: The median age …


Effect Of Adenotonsillectomy On Nocturnal Enuresis In Children With Obstructive Sleeping Apnea, Ramla Dahir Hersi, Hossam El-Sayed Elsisi, Ahmed Abdoo Elzehzahy Jan 2026

Effect Of Adenotonsillectomy On Nocturnal Enuresis In Children With Obstructive Sleeping Apnea, Ramla Dahir Hersi, Hossam El-Sayed Elsisi, Ahmed Abdoo Elzehzahy

Mansoura Medical Journal

Background: Nocturnal enuresis (NE) is the involuntary passage of urine during sleep and is a common condition in the pediatric population. Obstructive sleep apnea (OSA), characterized by recurrent episodes of upper airway obstruction during sleep, has increasingly been identified as a significant contributing factor to NE. Previous studies indicate that children with OSA have a higher prevalence of bedwetting than their healthy counterparts.

Objective: To assess the impact of adenotonsillectomy (AT) on NE in children diagnosed with obstructive sleep apnea.

Methods: This prospective study enrolled 20 pediatric patients presenting with both NE and OSA secondary to severe adenotonsillar hypertrophy. Tonsillar …


Clinico-Epidemiological Profile Of Iron Deficiency Anemia Among Egyptian Primary School Aged Children: A Hospital Based Study, Rabab Fathy Abdelhamid, Noha Essam, Mona Mohamed Taalab Jan 2026

Clinico-Epidemiological Profile Of Iron Deficiency Anemia Among Egyptian Primary School Aged Children: A Hospital Based Study, Rabab Fathy Abdelhamid, Noha Essam, Mona Mohamed Taalab

Mansoura Medical Journal

Background: Iron deficiency anemia (IDA) is the most prevalent cause of anemia among Egyptian children and is associated with a range of hematologic and non-hematologic complications, some of which may be irreversible. This study aims to evaluate the clinical profile and identify factors associated with severe IDA in primary school–aged children.

Methods: This cross-sectional study included 420 primary school–aged children diagnosed with IDA who attended the outpatient clinic of Salamoun El-Qumash Family Medicine Centre. Data were collected through face-to-face interviews using a structured questionnaire. All participants underwent a thorough clinical examination and laboratory evaluation, including a complete blood count and …


Effect Of Graft Steatosis On The Early Outcome Of Living Donor Liver Transplantation, Kareem Maher Shams Eldeen Hassan, Ahmed Mahmoud Abdelrafee, Ahmed Mohamed Ibrahim Elsabbagh, Mohamed Abd Elwahab Ali Jan 2026

Effect Of Graft Steatosis On The Early Outcome Of Living Donor Liver Transplantation, Kareem Maher Shams Eldeen Hassan, Ahmed Mahmoud Abdelrafee, Ahmed Mohamed Ibrahim Elsabbagh, Mohamed Abd Elwahab Ali

Mansoura Medical Journal

Background

Hepatic steatosis in donor grafts represents a growing challenge in living donor liver transplantation (LDLT) due to the rising prevalence of metabolic syndrome. The impact of varying degrees of graft steatosis on recipient and donor outcomes remains incompletely defined.

Aim

To evaluate the effect of different degrees of graft steatosis on early postoperative outcomes in both recipients and donors following LDLT.

Methods

This retrospective study analyzed 169 LDLT cases performed at Mansoura University between January 2014 and June 2024. Donors aged 18-45 years with BMI≥5% on liver biopsy were included. Grafts were stratified by steatosis degree:20% (n=4). Primary outcome …