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Letter From The Department Chair, William Munro Jan 2026

Letter From The Department Chair, William Munro

Res Publica - Journal of Undergraduate Research

No abstract provided.


The 2025 Michigan Supreme Court Ruling On Lwop Protections: Morally Justifiable?, Asa Smith Jan 2026

The 2025 Michigan Supreme Court Ruling On Lwop Protections: Morally Justifiable?, Asa Smith

Res Publica - Journal of Undergraduate Research

This paper examines the moral permissibility of the 2025 Michigan Supreme Court ruling that found life-without-parole (LWOP) sentences for 19- and 20-year-olds to be unconstitutional under Michigan state law. The paper supports its argument on whether the ruling was morally permissible by drawing on neuroscientific data as well as moral frameworks such as a rehabilitative theory of punishment and John Rawls’s ‘veil of ignorance’ thought experiment for the application of justified principles in society. The paper considers and replies to potential objections to its argument and to alternative interpretations of the moral frameworks it deploys. It concludes by contending that …


Ideological Narratives In Literacy Reform, Maya Mcgrew Jan 2026

Ideological Narratives In Literacy Reform, Maya Mcgrew

Res Publica - Journal of Undergraduate Research

This paper assumes a discourse analysis approach to examining if partisan control has influenced why red states have demonstrated faster gains in early literacy than blue states. This is done by investigating whether ideological presence in political framing, and particularly crisis-oriented rhetoric, drives reform adoption as much as policy design. Recognizing the ongoing discourse surrounding the continual improvement of pedagogy and programming, especially in areas of foundational skills such as reading, writing, comprehension, and oral communication. The research employs a systematic coding methodology, and the analysis combines a qualitative review of media narratives and state reform histories with a small-sample …


Between Motherhood And The Motherland: Navigating Challenges To Rank Advancement Of Women In The U.S. Army, Valeria Suarez Jan 2026

Between Motherhood And The Motherland: Navigating Challenges To Rank Advancement Of Women In The U.S. Army, Valeria Suarez

Res Publica - Journal of Undergraduate Research

Female officers remain a minority in the U.S. Army. Motherhood, dependent care, and sexual assault are some of the reasons why they decide to give up on their Army careers. The following study intends to examine how the impact of policy changes to accommodate female Army officers’ increased retention and consequently promoted the rank advancement of women to the rank of major, or O4 and above. Through conversations with 14 armed forces officers, both men and women, it is evident that the gender neutral culture of the Army proves to be detrimental to women’s rank advancement. For them to be …


Ranked Choice Voting At The State And Local Level, Khel Gordhan Jan 2026

Ranked Choice Voting At The State And Local Level, Khel Gordhan

Res Publica - Journal of Undergraduate Research

Many people across the political spectrum are frustrated with many of the problems that come with simple plurality voting, also known as first-past-the-post, which is implemented in the lion’s share of elections across the United States. To solve many of these problems, some activists and other political organizations advocate for cities and states to adopt Ranked Choice Voting (RCV) as a viable alternative. However, many people, both Republicans and Democrats, claim that implementing this system would be too complicated for people to understand. Due to this, there would be high rates of ballot exhaustion, which would disenfranchise vulnerable minorities who …


Little Saigon Vote: The Mobilization Of Vietnamese Voters Through Ethnic News Media, Vân Lê Jan 2026

Little Saigon Vote: The Mobilization Of Vietnamese Voters Through Ethnic News Media, Vân Lê

Res Publica - Journal of Undergraduate Research

Informed inspectors suspect Vietnamese Americans associate with the Republican Party because of the model minority mindset and their bond over the anti-Communist attitude. These two components created a sense of Vietnamese American nationalism in the refugee community. A way this Vietnamese American nationalism sustains is through ethnic media, which comes in many forms. The most prominent one is YouTube, where many Vietnamese voters (specifically the older generation) gain their political information from. This research seeks to explore how Vietnamese voters make their voting decisions based on the information that they consume by analyzing the content of the four most popular …


Are Ocular Markers Of Sun Exposure Associated With Skin Cancer? A Cross-Sectional Analysis Of The Busselton Healthy Ageing Study, Gareth Lingham, Vinay Kumar Nilagiri, Holly Brown, Chrianna Bharat, Samantha S.Y. Lee, Maria Franchina, Michael Hunter, Kevin Murray, David Alonso-Caneiro, Catherine M. Olsen, David C. Whiteman, David A. Mackey Jan 2026

Are Ocular Markers Of Sun Exposure Associated With Skin Cancer? A Cross-Sectional Analysis Of The Busselton Healthy Ageing Study, Gareth Lingham, Vinay Kumar Nilagiri, Holly Brown, Chrianna Bharat, Samantha S.Y. Lee, Maria Franchina, Michael Hunter, Kevin Murray, David Alonso-Caneiro, Catherine M. Olsen, David C. Whiteman, David A. Mackey

Research Outputs: 2025-Present

Background: Higher past sun or ultraviolet radiation exposure increases the risk of skin cancer and three common ocular findings: pterygium, conjunctival ultraviolet autofluorescence (CUVAF) and myopia. We investigated whether ocular markers of past sun exposure are associated with a history of skin cancer. Methods: A cross-sectional study of participants who attended the Phase 2 examination of the Busselton Healthy Ageing Study in Western Australia (2016–2022). Myopia was determined from autorefraction and pterygium and CUVAF from photographs of the anterior eye. Past diagnosis of a skin cancer was obtained from linked hospitalisation and cancer registry data (melanoma) or combining linked and …


Human Capability Development In Irish Tech Smes, Anna Zherdeva Jan 2026

Human Capability Development In Irish Tech Smes, Anna Zherdeva

Doctoral

Purpose: SMEs are the backbone of the European economic model and represent 99.8% of all businesses, highlighting the importance of research that assesses challenges and opportunities faced by SMEs. The reviewed literature revealed a significant lack of research on how SMEs can develop management, teamwork, and team-building skills in the context of the twin transition (i.e., digital and green transitions), particularly regarding digital transformation and its impact on economic development and business cooperation. Researchers have presented evidence of the difficulties SMEs face in competing with corporations due to numerous constraints, including a lack of investment and qualified human resources. To …


Motivation System Evoked By High Performance Work System In Chinese Universities And Colleges - An Examination Of The Relationship Between Human Resource Practices, Basic Psychological Needs, And Job Performance, Juan Chen Jan 2026

Motivation System Evoked By High Performance Work System In Chinese Universities And Colleges - An Examination Of The Relationship Between Human Resource Practices, Basic Psychological Needs, And Job Performance, Juan Chen

Doctoral

High Performance Work Systems (HPWS) are strategic, integrated Human Resource Practices (HRPS) designed to enhance employee abilities, motivation, and opportunities for participation, driving sustained organisational performance. While early research emphasized commitment HRPS, recent studies recognise that control and commitment HRPS are complementary rather than mutually exclusive, with neither holding an absolute advantage. Their success depends on contextual factors such as country, industry,organisation, economic environment, and workforce. In Chinese higher education institutions, transitioning from a high-commitment “iron rice bowl” system to a more control-oriented HR model has created tensions between efficiency and academic freedom. Based on the resource-based view, social exchange …


When Survival Becomes Politics: Necessity Activism And Identity Work Under Precarity, Lucia Garcia-Lorenzo, Lucia Sell-Trujillo, Paul Donnelly Jan 2026

When Survival Becomes Politics: Necessity Activism And Identity Work Under Precarity, Lucia Garcia-Lorenzo, Lucia Sell-Trujillo, Paul Donnelly

Research Outputs: 2025-Present

Collective action is essential for tackling social, institutional, and environmental challenges, often fueled by shared identities, common norms, and a belief in the possibility of change. However, the impact of participating in collective action on individual identities, and how this knowledge can shape future efforts to maintain engagement and promote positive change, remains underexplored. This study uses a liminal and identity work approach to examine how precarious Spanish activists, involved in long-term struggles against precarity, develop and negotiate their identities as activists through protest participation. Based on a qualitative study spanning over 9 years, this research focuses on the experiences …


Leveraging Natural Language Processing Methods For Next Generation Customer Service In Telecommunications Industry, Hesham Abdelmotaleb Jan 2026

Leveraging Natural Language Processing Methods For Next Generation Customer Service In Telecommunications Industry, Hesham Abdelmotaleb

School of Engineering, Computing and Mathematics Theses

This research explores application of Natural Language Processing (NLP) methods to better understand and improve customer service feedback in telecom industry. We collect novel reallife datasets of customer reviews and social media comments within British telecommunication industry over one year. Then, we apply three main modelling approaches. First, we study topic modelling for short text: we propose a new evaluation metric for GSDMM model and demonstrate that our metric helps to choose meaningful topics when texts are very brief. Second, we perform an extensive comparative study of word embedding models for text classification: we test nine word embedding and feature …


A Psychosocial And Psychometric Exploration Of Hikikomori In The Uk, Gregory Gorman Jan 2026

A Psychosocial And Psychometric Exploration Of Hikikomori In The Uk, Gregory Gorman

School of Psychology Theses

Hikikomori - originally identified in Japan as a severe form of social withdrawal - has evolved into a global phenomenon mirroring broader transformations in labour, technology, and identity. Once deemed a culture-bound syndrome, it is increasingly understood as a “society-bound” expression of psychosocial strain, existential unease, and retreat from normative life scripts. This thesis advances understanding of hikikomori by developing and validating psychometric tools, identifying subtypes of withdrawal, and situating the phenomenon within wider socio-cultural, digital, and philosophical frameworks.Empirical chapters detail the development of two novel tools: the Hikikomori Risk Inventory-13 (HRI-13) and the expanded Hikikomori Syndrome Behaviour Scale (HSBS). …


Modern Day Saints And The Production Of A Contemporary Pilgrimage Site: Comparative Analysis Of St. Pio Of San Giovanni Rotondo, Italy And Sai Baba Of Shirdi, India, Kiran Shinde, Anna Trono Prof Jan 2026

Modern Day Saints And The Production Of A Contemporary Pilgrimage Site: Comparative Analysis Of St. Pio Of San Giovanni Rotondo, Italy And Sai Baba Of Shirdi, India, Kiran Shinde, Anna Trono Prof

International Journal of Religious Tourism and Pilgrimage

Places valorised by saints have attracted pilgrimage for a long time as devotion to saints is a way to achieve both material wellbeing and spiritual growth. Yet, the cult following of modern-day saints in contemporary societies has become a topic for exploration only in recent years (Di Giovine, 2010; Shinde & Pinkney; 2013, Srinivas, 2008). A few excellent hagiographies discuss the material and non-material world created around charismatic modern-day saints with global followership (Waghorne, 2004; Weiss, 2005; Shepherd, 1986). Given the immense popularity of modern-day saints many questions arise- what kind of pilgrimage landscape is created around them? Are they …


Systematic Review Of Early Childhood And Pre-Primary Education, Anna Dabrowski, Yung Nietschke, Syeda Kashfee Ahmed, Michelle Hsien, Dan Cloney, Tim Friedman Jan 2026

Systematic Review Of Early Childhood And Pre-Primary Education, Anna Dabrowski, Yung Nietschke, Syeda Kashfee Ahmed, Michelle Hsien, Dan Cloney, Tim Friedman

Early Childhood Education

This systematic review synthesises global evidence from academic and grey literature published between 2015 and 2025, examining effective policies and interventions aimed at increasing ECCE participation across diverse country contexts, with a focus on equity dimensions such as gender, disability, socio-economic status and geographic location. The multifaceted nature of increasing ECCE participation is highlighted, exploring institutional, interventionist, preventative, and compensatory policies as per the GEM policy typology, while emphasising equity, quality, and contextual factors. These categories reflect the different levels and areas within which policies operate, noting that in practice, approaches to increase ECCE participation often are combined or overlap.


Generation Of Wave Turbulence In Dipolar Gases Driven Across Their Phase Transitions, Georgios A. Bougas, Koushik Mukherjee, Simeon Mistakidis Jan 2026

Generation Of Wave Turbulence In Dipolar Gases Driven Across Their Phase Transitions, Georgios A. Bougas, Koushik Mukherjee, Simeon Mistakidis

Physics Faculty Research & Creative Works

Ultracold quantum gases with long-range anisotropic interactions host novel exotic phases of matter, such as super solids, exhibiting both rigid and superfluid characteristics. The impact of this interplay on the out-of-equilibrium dynamics of dipolar gases, and in particular its connection with universal turbulent behavior, remains highly unexplored. Here, upon considering a dipolar Bose-Einstein condensate of dysprosium atoms being dynamically driven across the super solid-superfluid phase transition and vice versa, we unveil the emergence of a robust nonequilibrium quasi-steady state. This state displays self-similar momentum distributions exhibiting algebraic decay at large momenta, with scaling exponents supporting the existence of wave turbulence. …


Insights Into The Petrogenesis Of Alkalic, Shonkinitic Magmas From The Adel Hill Volcanic Field, Montana, Kenneth L. Brown, C. L. Mcleod, M. L. Lytle, T. J. Cracas, B. J. Shaulis, M. Loocke Jan 2026

Insights Into The Petrogenesis Of Alkalic, Shonkinitic Magmas From The Adel Hill Volcanic Field, Montana, Kenneth L. Brown, C. L. Mcleod, M. L. Lytle, T. J. Cracas, B. J. Shaulis, M. Loocke

Geology and Environmental Geoscience Faculty Publications

Shonkinites are rare alkali-rich igneous rocks found in the geological record from the Precambrian to the Eocene. This study investigates the Upper Cretaceous shonkinites from the Adel Hills Volcanic Field (AHVF), central Montana. The AHVF shonkinites are porphyritic with large, euhedral to subhedral phenocrysts of diopside that exhibit sector zoning. Other major mineral phases include plagioclase, sanidine, and secondary zeolites. Minor and accessory phases identified with SEM-EDS include magnetite, apatite, rare ilmenite and pyrite, and secondary calcite. Bulk rock SiO2 ranges from 47 to 49 wt% with Na2O + K2O varying from 5.50 to 7.34 wt% within that silica range. …


Perspectives Of Rural Educators On The Dependencies And Drawbacks Of Chat Gpt In Nigerian Higher Education Practices, Adedayo Olayinka Theodorio Dr, Francisca Jumoke Theodorio, Olumide Gbenga Olugbodi, Peter Adebowale Samson, Olusegun Olawale Olakotan Jan 2026

Perspectives Of Rural Educators On The Dependencies And Drawbacks Of Chat Gpt In Nigerian Higher Education Practices, Adedayo Olayinka Theodorio Dr, Francisca Jumoke Theodorio, Olumide Gbenga Olugbodi, Peter Adebowale Samson, Olusegun Olawale Olakotan

Journal of Educational Technology Development and Exchange (JETDE)

ChatGPT remains a valuable tool for transforming teaching strategies and supporting students’ comprehension of subject matter. However, its adoption and research remain uneven within the context of higher education in Nigeria. Specifically, there is limited empirical research that exemplifies real-world experiences regarding the dependencies and drawbacks in rural educational settings. This qualitative single-case study explored this phenomenon at a southwestern institution in Nigeria, involving a purposively selected group of educators. Data were gathered through participatory observation and focus group interviews, which were thematically analysed. The results indicated that the effective use of ChatGPT in rural higher education heavily depends on …


Governing By Fragments: Soviet Ruins And The Architecture Of Unaccountability In Kazakhstan, Robert A. Kopack, Magdalena E. Stawkoski Jan 2026

Governing By Fragments: Soviet Ruins And The Architecture Of Unaccountability In Kazakhstan, Robert A. Kopack, Magdalena E. Stawkoski

Faculty Publications

This article examines two case studies in Kazakhstan with research into how Soviet institutional legacies underwrite extractive economies that render toxic costs invisible in post-Soviet setting. Through ethnographic work in Stepnogorsk (uranium processing) and the Semipalatinsk Test Site (nuclear weapons testing), we extend Gabrielle Hecht’s residual governance framework to demonstrate how inherited bureaucratic compartmentalization now serves market rather than state interests. We introduce the concept of functional nonreform to describe how distributed actors maintain Soviet-era boundaries that prevent accountability: Agencies monitor but don’t enforce, health authorities lack jurisdiction over contaminated sites, and environmental agencies measure radiation but cannot restrict land …


Barriers To Mental Healthcare In Rural Agricultural Communities, Monica Salonga Jan 2026

Barriers To Mental Healthcare In Rural Agricultural Communities, Monica Salonga

Research Honors

Mental health diagnoses have become increasingly concerning in the United States (US). In 2024, 60 million adults in the United States experienced a mental illness, and over 14 million adults stated they had suicidal thoughts (Reinert et al., 2025). The Center for Disease Control (CDC) reports around 4,000 suicide-related deaths in the United States every year (CDC, 2025). One population that suffers from disproportionate rates of suicide is farmers and farm families. Farmers are ranked #4 in the United States regarding suicide rates (Miller & Rudolphi, 2022). Between 2003 and 2018, there were 1,935 suicide-related deaths committed by farmers (Miller …


Dari Ottawa Hingga Jenewa: Refleksi Perjalanan Promosi Kesehatan, Dien Anshari Jan 2026

Dari Ottawa Hingga Jenewa: Refleksi Perjalanan Promosi Kesehatan, Dien Anshari

Perilaku dan Promosi Kesehatan: Indonesian Journal of Health Promotion and Behavior

No abstract provided.


Front Matter, Editors Of Osgoode Hall Law Journal Jan 2026

Front Matter, Editors Of Osgoode Hall Law Journal

Osgoode Hall Law Journal

Front Matter


Missionary Body Politics: Physical Education In West China, 1905-1950, Cory Willmott Jan 2026

Missionary Body Politics: Physical Education In West China, 1905-1950, Cory Willmott

Asia Pacific Perspectives

Republican Era China saw a radical transformation in Chinese physical culture as it aimed to compete in the global geopolitics of nation-states. Employing an historical ethnographic approach, this paper outlines how the unique conditions of Sichuanese warlordism and secret societies affected missionary relations with the Guomindang (GMD) as they implemented increasingly militarized physical education programs. Before the 1928 GMD consolidation of power, missionaries and GMD educators aligned with the YM/ WCA in physical education programs. After the GMD moved their headquarters to Chongqing in 1938, relations soured between the GMD and the Sichuan missionaries. Although the latter had been the …


Pilot Study On The Use Of Multimorbidity Index In Patients Receiving Home Parenteral Nutrition, Michael M. Rothkopf, Mohan Pant, Zachary Rothkopf, Rebecca Brown Rdn, Jaime Haselhorst Rdn, Debbie L. Stevenson Rdn, Andrew Depalma Mba, Michael Saracco Jan 2026

Pilot Study On The Use Of Multimorbidity Index In Patients Receiving Home Parenteral Nutrition, Michael M. Rothkopf, Mohan Pant, Zachary Rothkopf, Rebecca Brown Rdn, Jaime Haselhorst Rdn, Debbie L. Stevenson Rdn, Andrew Depalma Mba, Michael Saracco

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background

Home parenteral nutrition (HPN) patients often have multiple comorbidities. A validated multimorbidity index (MMI) could help determine resource needs and risks with HPN. We evaluated MMI scoring to determine if it predicted HPN resource use and outcomes.

Methods

We performed a secondary analysis of 60 HPN patients from a previous study based on Cumulative Illness Rating Scale (CIRS) scoring. We examined three variables: PN formula changes, hospitalizations, and hospital length of stay (LOS). Density plots were produced to select a CIRS score cutoff value. Spearman correlations among the three variables of interest were computed. The data were then subjected …


A Critical Perspective On The Society Of Environmental Toxicology And Chemistry's Adherence To Founding Principles— Opportunities For The Future, Barnett A. Rattner, Annegaaike Leopold, Carys L. Mitchelmore, Glenn W. Suter, Mark S. Johnson, Adriana C. Bejarano, Lawrence A. Kapustka, Niranjana Krishnan, Derek C. G. Muir, Beatrice O. Opeolu, Martha Georgina Orozco-Medina, April Reed, Bruce W. Vigon, Adam R. Wronski Jan 2026

A Critical Perspective On The Society Of Environmental Toxicology And Chemistry's Adherence To Founding Principles— Opportunities For The Future, Barnett A. Rattner, Annegaaike Leopold, Carys L. Mitchelmore, Glenn W. Suter, Mark S. Johnson, Adriana C. Bejarano, Lawrence A. Kapustka, Niranjana Krishnan, Derek C. G. Muir, Beatrice O. Opeolu, Martha Georgina Orozco-Medina, April Reed, Bruce W. Vigon, Adam R. Wronski

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

The Society of Environmental Toxicology and Chemistry (SETAC) is a global organization whose mission is the advancement of environmental science and management through collaboration, leadership, communication and education. On SETAC's 45th anniversary, the following question was raised: Are the 1979 founding principles of SETAC, multidisciplinary approaches to solving environmental problems, multisector engagement and scientific objectivity, still useful, adequate and effective in fulfilling its mission? In a special session held at the 45th Annual Meeting in Fort Worth, Texas, United States, a critical evaluation of the founding principles was initiated by reviewing SETAC's history and ongoing activities, and recommendations were made …


The Crucial Role Of Machine Learning Models In Predicting Current Childhood Asthma: Model Comparison, Calibration, And Shap-Based Interpretation, Aditya Chakraborty, A. K.M. Raquibul Bashar Jan 2026

The Crucial Role Of Machine Learning Models In Predicting Current Childhood Asthma: Model Comparison, Calibration, And Shap-Based Interpretation, Aditya Chakraborty, A. K.M. Raquibul Bashar

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background: Asthma is one of the most prominent chronic diseases in children and one of the most challenging ailments to diagnose in infants and preschoolers in the United States. Predictive models can be instrumental in improving early diagnosis, personalized treatment strategies, and disease progression. By utilizing nationalized data, this study focuses on building and comparing high-performing analytical predictive models based on the relevant risk factors and identifying the most influential predictors.

Methods: We analyzed cross-sectional BRFSS Asthma Call-Back Survey data (2011-2020; N = 9,813) and randomly split participants into training and testing sets. An XGBoost model (hyperparameters tuned via grid …


Mary Elizabeth Frayser Papers - Accession 1739, Mary Elizabeth Frayser Jan 2026

Mary Elizabeth Frayser Papers - Accession 1739, Mary Elizabeth Frayser

Manuscript Collection

The Mary Elizabeth Frayser Papers document the professional career, civic engagement, and reform work of Mary E. Frayser, an educator, home economist, social worker, and prominent women’s club leader in South Carolina during the twentieth century. The collection reflects Frayser’s long-standing commitment to education, social welfare, women’s rights, and public policy, as well as her involvement in numerous state and regional organizations dedicated to social and economic reform.

Materials in the collection include newspaper clippings, correspondence, speeches, reports, articles, pamphlets, meeting-related documents, publications, and other printed materials. These records document Frayser’s work with the South Carolina Extension Service (1912–1940), Winthrop …


Rev. William Cummins Davis Collection - Accession 1782, William Cummins Davis Jan 2026

Rev. William Cummins Davis Collection - Accession 1782, William Cummins Davis

Manuscript Collection

The Rev. William Cummins Davis Collection consists primarily of a bound 1823 volume titled Lectures on the New Testament: In Which the Four Evangelists Are Harmonized, and the Work Interspersed with Critical Notes and Observations on Several Passages. Published posthumously by Davis’s eldest son, the Rev. Robert M. Davis (1793–1824), this volume is one of eight issued in a projected series originally intended to comprise only two volumes. The work compiles sermons, theological lectures, and critical annotations reflecting Davis’s distinctive interpretations of the New Testament.

William Cummins Davis (1760–1831) was a prominent and controversial Presbyterian minister in the Carolinas …


Dcmm-Transformer: Degree-Corrected Mixed-Membership Attention For Medical Imaging, Huimin Cheng, Xiaowei Yu, Shushan Wu, Luyang Fang, Chao Cao, Jing Zhang, Tianming Liu, Dajiang Zhu, Wenxuan Zhong, Ping Ma Jan 2026

Dcmm-Transformer: Degree-Corrected Mixed-Membership Attention For Medical Imaging, Huimin Cheng, Xiaowei Yu, Shushan Wu, Luyang Fang, Chao Cao, Jing Zhang, Tianming Liu, Dajiang Zhu, Wenxuan Zhong, Ping Ma

Computer Science Faculty Research & Creative Works

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures through stochastic binary masking, they suffer from non-differentiability, training instability, and the inability to model complex community structure. We present DCMM-Transformer, a novel ViT architecture for medical image analysis that incorporates a Degree-Corrected Mixed-Membership (DCMM) model as an additive bias in self-attention. Unlike prior approaches that rely on multiplicative masking and binary sampling, our method introduces community structure and degree heterogeneity in a fully differentiable and interpretable manner. Comprehensive …


Surgical Treatment Of Osteoradionecrosis Of The Jaw Following Radiotherapy For Oropharyngeal Cancer: A Retrospective Clinical Analysis In A Single-Center, Yu Nakai, Ken-Ichiro Sakata, Kazuhito Yoshikawa, Taku Maeda, Tougo Tanabe, Masayuki Shinohara, Kenji Imamachi, Hiroshi Hikasa, Jun Sato, Ikuya Miyamoto Jan 2026

Surgical Treatment Of Osteoradionecrosis Of The Jaw Following Radiotherapy For Oropharyngeal Cancer: A Retrospective Clinical Analysis In A Single-Center, Yu Nakai, Ken-Ichiro Sakata, Kazuhito Yoshikawa, Taku Maeda, Tougo Tanabe, Masayuki Shinohara, Kenji Imamachi, Hiroshi Hikasa, Jun Sato, Ikuya Miyamoto

Journal of Dental Sciences

Background/purpose: Osteoradionecrosis of the jaw (ORNJ) is an intractable disease that develops within the radiation field in patients with head and neck cancer. This study aimed to investigate differences in healing rates among surgical treatments for mandibular ORN that developed after radiotherapy for oropharyngeal cancer.

Materials and methods: We retrospectively evaluated 318 patients who underwent radiotherapy or chemoradiotherapy for oropharyngeal cancer at our institution to determine the incidence of ORNJ. Furthermore, 16 patients (15 males and 1 female) with a mean age of 63.3 years were included in the surgical analysis. Healing was defined as the absence of …


N-Acetylcysteine Restores Osteogenesis In Human Periodontal Ligament Stem Cells By Attenuating Hif-1Α-Driven Oxidative Stress And Glycolytic Reprogramming, Xiaochi Chang, Yanghao Zhao, Yang Wang, Chang Shu, Yi Feng, Yichong Sun, Guangxun Zhu, Jianxia Hou Jan 2026

N-Acetylcysteine Restores Osteogenesis In Human Periodontal Ligament Stem Cells By Attenuating Hif-1Α-Driven Oxidative Stress And Glycolytic Reprogramming, Xiaochi Chang, Yanghao Zhao, Yang Wang, Chang Shu, Yi Feng, Yichong Sun, Guangxun Zhu, Jianxia Hou

Journal of Dental Sciences

Background/purpose: Periodontitis-associated hypoxia signaling and oxidative stress severely impair the regenerative capacity of human periodontal ligament stem cells (hPDLSCs). This study investigated whether antioxidant intervention rescues hPDLSC osteogenesis under CoCl₂-induced HIF-1α stabilization by modulating PI3K/Akt/HIF-1α/HO-1 signaling and glycolytic reprogramming.

Materials and methods: Primary hPDLSCs isolated from healthy premolars were characterized by flow cytometry and multilineage differentiation. To simulate periodontitis-associated stress, a CoCl₂-induced HIF-1α-stabilizing condition was established. Cells were treated with the antioxidant N-acetylcysteine (NAC), the glycolysis inhibitor 2-deoxy-D-glucose (2-DG), or the PI3K inhibitor LY294002. Redox balance (DCFH-DA, MDA, GPX activity), glycolysis-related markers (HK2, GLUT1, lactate), and osteogenic-related markers …