Digital Commons Network^™

Guidebook For Artificial Intelligence Integration Into The University Environment, Mark J. Uline, Tarek Shazly, Grace Cosby

Reports

Artificial Intelligence (AI) is not a peripheral or speculative technology in the university setting, it is rather a rapidly evolving transformational force that will reshape research, teaching, and administrative operations. Recent systematic reviews conclude that generative AI tools are already being widely used by students and instructors and can positively affect learning outcomes and academic performance when thoughtfully integrated into instruction (Hon, 2025; Qian, 2025).

At the same time, case studies warn that unmanaged or poorly governed AI use can undermine academic integrity, exacerbate inequities, and create new institutional risks (Mangundu, 2025; Şen et al., 2026). AI adoption brings unparalleled …

Scientific Kenyon: Neuroscience Edition (Full Issue)

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

My Brain Didn't Get The Memo That It Was Virtual, Samantha Ofori

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Epigenetic Hangovers: Your Brain On Alcohol, Cindy Chen

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Losing Yourself To Find Yourself: The Neuroscience Ego Dissolution, Mike D'Eletto

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

Smile! Your Brain Is On Camera, Natalie Stone

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

When Empathy Goes Quiet, Miko Warshaw

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

The 400 Millisecond Mind, Adrian Mangine

Scientific Kenyon: The Neuroscience Edition

No abstract provided.

The Heterotopic Horizon In Zora Neale Hurston’S Their Eyes Were Watching God, Emily Norton

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

An Interview With David Nolan, Teri Sopp

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

Norman Berg And The Literary Formation Of Pat Conroy, Jacob Lupfer

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

“Ora’S Deep Lament”: Inspired By Mk Rawlings And My Persevering Pioneer Great-Grandmother, Kathlyne Mcdonald Walkup Sheppard

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

Utility Of Model-Based And Probabilistic Approaches For Rocket Engine Affordability : Exemplified On The Rs-25 Engine, Shreyas Lakshmipuram Raghu

Dissertations

Rocket engine development has historically relied on test–fail–fix (TFF) methodologies to uncover structural and fatigue deficiencies under representative operating conditions. While effective, TFF is inherently costly and schedule-intensive, often revealing life-limiting behavior late in the development lifecycle. The increasing use of additive manufacturing (AM) amplifies this challenge by introducing material property scatter and process-induced variability. Without explicit early treatment of uncertainty, these effects can increase reliance on physical testing and drive additional TFF cycles. This work presents a reliability-driven life-consistent design-bounding framework intended as an early lifecycle decision-support tool to assess and mitigate TFF risk. Although material variability is inherently …

Exploring Pregnancy-Related Empowerment And Person-Centered Prenatal Care In Black Pregnant And Postpartum Women In Alabama, Lauren Milam

Dissertations

Black women in the United States experience disproportionately high rates of maternal morbidity and mortality and often report feeling unheard, dismissed, or excluded from decision-making during pregnancy and childbirth. Understanding how Black women experience prenatal care and how those experiences relate to empowerment during pregnancy is essential for improving care and addressing persistent inequities. This study examined the relationship between person-centered prenatal care and pregnancy-related empowerment and explored Black women’s prenatal care experiences in Alabama using a sequential Quan → QUAL mixed methods design. In the quantitative phase, relationships among person-centered prenatal care, pregnancy-related empowerment, and care-related factors were examined …

We Mourn, We Stir, We Pick Up The Pieces., Sara Menco Arenas

Digressions: Literary & Art Journal

No abstract provided.

Contributor Biographies

Digressions: Literary & Art Journal

No abstract provided.

Rna-Micelles As Self-Assembling Structures For Efficient Co-Delivery Of Synergistic Sirna And Nucleoside Analogues To Treat Crc Lung Metastasis, Kai Jin, Piotr G. Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo

Markey Cancer Center Faculty Publications

SiRNA has been widely studied in cancer gene silencing over the last 25 years. However, few siRNA-based therapeutics have been approved by the FDA. An RNA-micelle platform provides a powerful therapeutic tool through simple one-step, high-yield production that is capable of efficient colorectal cancer lung metastasis treatment, a current lethal condition with a short survival rate post-diagnosis. Here, it is reported that the use of RNA-micelles co-carrying siRNA and nucleoside analogues to completely inhibit lung metastasis of colorectal cancer (CRC). The major advantage of the RNA-micelle is the successful co-delivery of siRNA and chemotherapeutic agent in a single delivery vehicle …

Case Report: Prolonged Response To Cabozantinib And Pembrolizumab In Treatment-Refractory Metastatic Pancreatic Ductal Adenocarcinoma, Anna M. Reagan, Hannah G. Mcdonald, Jaewon Kang, Hoda Saghaeiannejad Esfahani, Caroline G. Wright, Charles J. Bailey, Carleton S. Ellis, Kaylyn R. Collette, Reema A. Patel, Mayte Murillo, Samantha F. Stokley, Michael J. Cavnar, Prakash Pandalai, Mautin T. Barry-Hundeyin, Jessica Moss, Joseph Kim

Markey Cancer Center Faculty Publications

Immunotherapy has yet to demonstrate durable efficacy in pancreatic ductal adenocarcinoma (PDAC) despite the fact that pancreatic cancer cells have higher levels of immune checkpoint expression than other cancer cell types in which immunotherapy efficacy has been well established. We observed effective cytotoxicity with the combination therapy of pembrolizumab (an anti-PD-1 monoclonal antibody, mAb) and cabozantinib (an anti-MET small molecule) in vivo. This served as the basis for an investigator-initiated phase II clinical trial (NCT05052723). The trial was open to patients with treatment-refractory metastatic PDAC with a single-arm treatment protocol of pembrolizumab and cabozantinib. Here, we report the case of …

Assessing The Value Of Sequential Next-Generation Sequencing And Multiple Molecular Tumor Board Reviews For Patients With Solid-Tumor Malignancies, Allison L. Swiecki-Sikora, Lydia Williams, Ning Li, Donglin Yan, Evan Bryon, Derek B. Allison, Rachel W. Miller, Charles S. Dietrich, Jill M. Kolesar

Markey Cancer Center Faculty Publications

Purpose: Multidisciplinary molecular tumor boards (MTBs) have demonstrated improved clinical outcomes in various malignancies. Sequential next-generation sequencing (NGS) is widely performed at the time of recurrence, which may lead to multiple MTB reviews. This study assessed the clinical benefit of multiple MTB reviews for sequential NGS.   Methods: A retrospective cohort review was performed to compare patients reviewed once at a single-institution MTB and those reviewed multiple times for the same diagnosis with sequential NGS between January 2016 and December 2023. Demographics were compared, and regression and survival analysis was performed.   Results: In all, 3,702 patients were included, 3,446 (91.6%) were …

Case Report: Prostate Adenocarcinoma With Peritoneal Carcinomatosis And Elevated Cea Mimicking Colorectal Cancer: A Diagnostic Dilemma, Hala Majeed, Nathan R. Shelman, Jitesh A. Patel, Janeesh S. Veedu, Insija I. Selene, Ashlyn Whitesell, Zin W. Myint

Markey Cancer Center Faculty Publications

This case report describes an exceptionally rare manifestation of prostate adenocarcinoma presenting with peritoneal carcinomatosis, rectal obstruction, and markedly elevated carcinoembryonic antigen (CEA), closely mimicking colorectal cancer. A 65-year-old man with localized high-grade prostate adenocarcinoma (Gleason 4 + 4) underwent robotic prostatectomy in November 2020, followed by salvage radiation and stereotactic body radiation therapy for early biochemical recurrence. He achieved an excellent response to androgen deprivation therapy (ADT) combined with abiraterone and prednisone, maintaining an undetectable prostate-specific antigen (PSA) level for over 2 years. In late 2024, the patient developed hematochezia, narrow stools, and abdominal pain. Imaging revealed a rectal …

Eef2k Promotes Immune Evasion In Melanoma Via Cyclin D1–Mediated Stabilization Of Pd-L1, Yijie Ren, Darby J. Ballard, Anil Kumar, Andy F. Song, Mitiksha Gupta, Xiaofang Xiong, Xingcong Ren, Jugal Kishore Das, Jin-Ming Yang, Jianxun Song

Markey Cancer Center Faculty Publications

Eukaryotic elongation factor 2 kinase (eEF2K) is a stress-responsive regulator of protein synthesis implicated in melanoma progression, but its role in tumor immune evasion remains poorly defined. We investigated how eEF2K influences programmed death ligand 1 (PD-L1) expression through modulation of Cyclin D1. We analyzed gene expression and dependency datasets from The Cancer Genome Atlas and the Cancer Dependency Map. Protein–protein interactions were assessed by co-immunoprecipitation. Cyclin D1 was inhibited pharmacologically with palbociclib. Immune responses were evaluated in murine B16-OVA and human A2058 melanoma models using flow cytometry and immunohistochemistry after genetic or pharmacologic modulation of eEF2K and Cyclin D1. …

Characteristics Of The Health-Associated Oral Microbiome In Young Nonhuman Primates, J. L. Ebersole, O. A. Gonzalez

Markey Cancer Center Faculty Publications

Nonhuman primates have been shown to develop periodontitis with clinical and demographic features similar to humans. This preclinical disease model is well-positioned to advance the elucidation of novel biologic-based preventive and therapeutic approaches to controlling periodontitis, a chronic infection and immunoinflammatory disease. In this analysis, the oral microbiomes of younger (10–19 human years; n = 30) nonhuman primates are compared for matriline (an indicator of heritability), sex, and age variations. A holistic assessment of the microbiome similarities/differences suggested two primary conclusions in this younger group of orally healthy nonhuman primates. First, at the microbiome level of phyla, orders, and families, …

Prognostic Value Of Lung Injury Biomarkers In Patients Hospitalized With Covid-19 Without Respiratory Failure At Admission, Jennifer G. Wilson, Greg A. Grandits, Birgit Grund, Shweta S. Mistry, Carolyn Leroux, Angelika Ringor, Neil R. Aggarwal, Daniel D. Murray, Christina E. Barkauskas, Samuel M. Brown, Elizabeth Higgs, Kathryn Shaw-Saliba, Adam Rupert, Virginia L. Kan, Jeremy R. Beitler, Omar Awan, Jamie L. Sturgill, Halima Dawood, Andre C. Kalil, Ioannis Kalomenidis, Abhijit Duggal, Sarah C. Sasson, Minh Q. Ho, Hien H. Nguyen, Jens D. Lundgren, Adit A. Ginde, Wesley H. Self, H. Clifford Lane, Michael A. Matthay, Angela J. Rogers

Markey Cancer Center Faculty Publications

Objectives: – The COVID-19 pandemic highlighted an urgent need to more efficiently identify patients at highest risk for developing respiratory failure. We investigated whether plasma levels of lung injury biomarkers are associated with progression to respiratory failure among adults hospitalized with COVID-19 pneumonia without respiratory failure at admission. Design: – This was a nested case-control study of COVID-19 patients enrolled in the Accelerating COVID-19 Therapeutic Interventions and Vaccines-3 (ACTIV-3)/Therapeutics for Inpatients with COVID-19 (TICO) platform trial who were on less than 20 L/min supplemental oxygen at enrollment. We compared baseline measurements of lung injury biomarkers between participants who progressed to …

Improving Blood Pressure Control Through Lifestyle Modification In African Americans Adults With Uncontrolled Hypertension, Tasha Leonard

Doctor of Nursing Practice (DNP) Scholarly Projects

African American adults have the highest incidence of uncontrolled hypertension (HTN), leading to premature cardiovascular death in Texas and worldwide. In a South Texas cardiac clinic, over 90% of African American adults with HTN also have obesity, compared with 55% of their Caucasian counterparts. The most prevalent factor affecting this group is poor understanding of blood pressure management, which leads to nonadherence to dietary and exercise recommendations, medication regimens, and blood pressure monitoring. The objective was to determine whether lifestyle modification using a hypertensive bundle would improve blood pressure management among African American adults in the clinical setting. The initiative …

Thermodynamics Of Bubble-Through Liquid-Core Nuclear Thermal Rockets, Dakota John Santana

Dissertations

Liquid-Core Nuclear Thermal Rockets (LNTR) were originally investigated in the 1960s. Exploratory efforts have thus far been relegated to preliminary models that illustrate proof-of- concept or identify theoretical limits. Collectively they would report ranges for 𝐼𝑠𝑝 between 1000 −2000 𝑠 and thrust-to-weights between 0.5 −6. This work expands a model for the Bubbler class of LNTRs into an engineering model suitable for design exploration and system model integration. Bubblers use centrifugal force to trap molten fissile fuel while bubbling propellant radially inward to cool structural members and achieve temperatures >4500 𝐾. The Bubbler model detailed herein, dubbed Fornax, expands the …

Improving Patient Adherence To Telehealth Appointments By Implementing A Bundle Intervention, Steve Erimwioghae

Doctor of Nursing Practice (DNP) Scholarly Projects

Background: Missed appointments undermine the benefits of telepsychiatry. An outpatient psychiatric practice in Texas reported a baseline no-show rate of 30.4%, exceeding national average and disrupting continuity of care, clinic efficiency, and revenue.

Purpose: Implement and evaluate a telepsychiatry adherence bundle—tiered automated reminders, structured pre-visit check-ins, and patient education—to reduce the no-show rate among adults receiving outpatient telepsychiatry care.

Methods: A pre- and post-quality improvement project, guided by the Plan-Do-Study-Act (PDSA) framework, delivered the bundle to all scheduled adult patients over eight weeks. De-identified appointment and demographic data were analyzed in SPSS using descriptive statistics and the …

A Guideline To Address Barriers To Mental Health Treatment Experienced By Law Enforcement Officers, Jacqueline Estrella

Doctor of Nursing Practice (DNP) Scholarly Projects

Problem: Law enforcement officers are exposed to repeated trauma on the job that may negatively affect their mental health. Officers may avoid seeking mental health treatment due to police culture, stigma, and other barriers which may increase risks for suicide, absenteeism, and maladaptive coping.

Objectives: Develop an evidenced-based guideline to address barriers law enforcement officers face in seeking mental health treatment.

Methods: The National Quality Measures Clearinghouse (NQMC) Domain Framework was used to guide a literature review to identify best practices suitable for a guideline. Articles were graded for strength based on the John Hopkins Nursing Evidence Based Practice (JHNEBP) …

Diffusion Of Excitons In Thin Films Of Quantum Dots, Dustin Roberts

Dissertations

Quantum dots are heavily used in modern devices, such as consumer television screens, lasers, medical sensors, solar cells, and quantum computing. Their tunability and photo-stability make them candidates for a variety of applications which formerly required either dyes or significant amounts of band structure engineering. Despite all of the current and active applications, there is a gap in the current literature with regards to how energy is transported through thin films of quantum dots, and what methods may be used to control transport direction and range. The goal of this dissertation is to help fill those gaps, towards the end …

The Global Privacy Frontier: Bridging User Expectations And Ai In Mental Health Technology, Salauddin Ahmed, Mohammad Asaduzzaman

Student Publications

This study examines privacy concerns in AI-driven mental health apps through the lens of Communication Privacy Management (CPM) theory, utilizing qualitative research of consumer opinions on Google Play Store. It explores how global consumers articulate privacy concerns, experience boundary turbulence in online conversations, and exhibit culturally oriented privacy expectations in this high-stakes emerging tech arena. Results indicate that users are most likely to voice concerns about control and transparency of data, with ambiguous privacy policies raising suspicion. Boundary turbulence narratives, e.g., improper use of data, are most directly related to loss of trust and app abandonment, highlighting critical challenges for …

How Wasteful Is Signaling?, Alex Frankel

Cowles Foundation Discussion Papers

Signaling is wasteful. But how wasteful? We study the fraction of surplus dissipated in a separating equilibrium. For isoelastic environments, this waste ratio has a simple formula: β/(β + σ), where β is the benefit elasticity (reward to higher perception) and σ is the elasticity of higher types’ relative cost advantage. The ratio is constant across types and independent of other parameters, including convexity of cost in the signal. A constant waste ratio characterizes the isoelastic class. In winner-take-all signaling tournaments with N candidates, exactly (N − 1)/N of the surplus dissipates—the same as in Tullock contests.