Digital Commons Network^™

A Phosphorylation Study Of Serine-8 And 26 In Two Fragments Of Amyloid Beta, A Peptide Involved In Alzheimer's Disease And Cancer, Colby J. Merrill

Senior Honors Theses and Projects

Both cancer and Alzheimer’s disease (AD) affect many people in the United States and impact the families of patients suffering from these challenging illnesses. Recently, it has been reported that these two diseases share several key pathophysiological features, and an inverse relationship exists between them. These diseases share several biochemical modulators, most notably the amyloid-beta protein, which affects tissues in both AD and cancer by misfolding and aggregating. Phosphorylation is believed to regulate the aggregation and toxicity of amyloid-beta by altering the protein's shape and charge, thereby changing its interactions with cells. Phosphorylation can also toggle some proteins on and …

The Impact Of Michigan's Public Act 308 On Foster Care Outcomes: A Synthetic Control Analysis, Maruis D. Martello

Senior Honors Theses and Projects

This paper evaluates the impact of Michigan’s 2014 Public Act 308 on foster care adoption outcomes. By converting traditional adoption subsidies into dynamic, redeterminable contracts, the policy aimed to reduce the financial uncertainty associated with adopting children with latent or evolving special needs. Using data from the Adoption and Foster Care Analysis and Reporting System (AFCARS) from 2000 to 2022, we implement a generalized synthetic control method to account for unobserved time-varying heterogeneity. We find that the policy had no statistically significant impact on the aggregate adoption rate. However, it generated significant gains within targeted subpopulations, increasing the probability of …

Food Insecurity In Older Adults With Cancer, Page Laborde

Senior Honors Theses and Projects

Food insecurity is a growing concern among older adults and is associated with poor health outcomes, particularly among those with cancer. Community-based programs such as Meals on Wheels may help address these challenges, but their role in supporting older adults with cancer is not well understood. This study examined the association between recent non-skin cancer diagnosis and food insecurity, as well as relationships with Meals on Wheels participation. A cross-sectional analysis was conducted using secondary data from Rounds 9 through 14 of the National Health and Aging Trends Study (NHATS), a nationally representative sample of U.S. adults aged 65 and …

Headset Chatter, Lynn G. Lower

Senior Honors Theses and Projects

No abstract provided.

Investigating The Effects Of Atg3 On Autophagosome Size And Number, Keeran R. Senthil Kumar

Senior Honors Theses and Projects

Macroautophagy, or autophagy, is a highly conserved catabolic process in all eukaryotes which allows for the degradation of large cytosolic contents. It occurs in two forms: bulk autophagy, which is induced by nutrient deprivation and targets nonspecific cargo, and selective autophagy, which is induced by cellular stress and sequesters specific substrates. The process of autophagosome formation is carried out by a group of Atg (autophagy-related) proteins, one of which is Atg3. Atg3 functions as an E2-like enzyme by conjugating Atg8 — a ubiquitin-like protein — to phosphatidylethanolamine (PE), a step required for autophagosome membrane formation. This lipidation process is catalyzed …

How Candidates Campaign To Sway Minority Voter Bases, Katelyn Karwick

Senior Honors Theses and Projects

Religious groups in the United States are making large partisan switches–decades-long Democrats are questioning their support and often change their vote to another party. This phenomenon contributed to Michigan’s flip to Republican in the 2024 presidential election, as well as divided Jewish support for New York City mayoral candidate Zohran Mamdani. Past research has linked a positive correlation between religious participation and political mobilization, though the tactics used by campaigners to create this connection have gone under research. Looking at Donald Trump’s victory in Dearborn, Michigan in 2024 and Zohran Mamdani’s extensive New York City mayoral campaign, this study focuses …

The Effects Of Nature Exposure On Workplace Engagement, Allison Emmons

Senior Honors Theses and Projects

The idea that nature is beneficial to humans is somewhat unclear in the field of psychology. Many studies have found that exposure to natural elements can improve human emotions and performance on cognitive tasks. However, there are inconsistencies in the literature regarding whether both outcomes can be enhanced at once. There is also limited research on how nature can impact attitudes about the environment and tasks at hand. This study seeks to examine whether or not incorporating natural elements into workplaces improves employee performance and engagement measures, such as decision-making quality, job satisfaction, job motivation, and current emotional state. This …

Examining Weight Related Attitudes And Health Behaviors Among College Students, Alexis C. Denski

Senior Honors Theses and Projects

BACKGROUND: College is a pivotal period for the development of lifelong health behaviors. Factors such as greater personal freedom, poor diet, social norms, and insufficient physical activity (PA) contribute to common weight gain and increase of body image challenges. Although many college students report trying to lose weight, there is limited research examining if their PA and dietary behaviors align with evidence-based health recommendations. PURPOSE: Examine the proportion of college students trying to change their weight and their engagement in weight-related behaviors such as PA, strength training (ST), and dietary factors. METHODS: In Fall 2019, a random sample of 5,000 …

Affirmative Action In The Supreme Court, Arianne K. Dacayo

Senior Honors Theses and Projects

No abstract provided.

Blunt Relief: Cannabis Use As Coping Mechanism For Undergraduate Students With Adverse Healthcare Experiences, Isabella Marie Cafini

Senior Honors Theses and Projects

Negative experiences within the healthcare system can shape how individuals cope with psychological distress, particularly in young adult populations. Coping-motive frameworks suggest that when trust in formal support systems erodes, such as after an adverse healthcare experience, individuals may self-medicate with substances rather than risk another unsupportive interaction. This present study examined how negative experiences within the mental healthcare system influence help-seeking attitudes and cannabis use among college students. We hypothesized that (1) individuals with lower utilization of mental health resources will have higher cannabis use compared to those with higher utilization of mental health resources, and (2) greater amounts …

How Nature Affects Perceptions Oaf Architectural Details In Office Settings, Autumn R. Hurd

Senior Honors Theses and Projects

The importance of nature in our everyday lives has been well documented and researched. Theories such as the Biophilia Hypothesis, Stress Reduction Theory, and Attention Restoration Theory each attempt to explain why nature influences psychological states. The present research examined the influence of nature in office settings, such that offices with real nature would be seen as more appealing. It was hypothesized that participants would view offices with real plants and nature within or near the settings would be seen as more appealing as compared to similar offices with either AI-Generated nature or no nature within or near the office …

Soil Texture Does Not Affect Multi-Mutualist System Benefits In Prairie Legumes, Ambrose O. Cook

Senior Honors Theses and Projects

No abstract provided.

A Comprehensive Overview Of Prison Rape And The Impacts Of The Prison Rape Elimination Act, Kayn L. Bienhold

Senior Honors Theses and Projects

This paper will examine prison rape by exploring sexual abuse rates, the causes of underreporting, the gender-based prison and rape cultures, reasons why victims are targeted, and the impact The Prison Rape Elimination Act (PREA) has had on the issue. It draws on both qualitative research and national surveys. Findings have shown that sexual victimization is much more widespread than indicated by official reports due to high rates of underreporting, fears of retaliation, and flawed implementation and enforcement of PREA’s policies. Culture in male prisons are shaped by hypermasculine hierarchies that discourage reporting, while female prisons experience disproportionately high rates …

Should Citizens Or Politicians Draw The Lines: A Michigan Case Study, Grant M. Clark

Senior Honors Theses and Projects

The American system of government requires that voters be able to choose their politicians, not the other way around. For centuries, politicians of all stripes have utilized the redistricting process to draw electoral districts that benefit themselves and their political party. This practice has triggered calls for redistricting reform at the national and state levels, including in Michigan. This research provides a case study of the Michigan Independent Citizens Redistricting Commission (MICRC). It focuses on the commission’s activities as part of a national conversation about redistricting reform and the use of Independent Redistricting Commissions (IRCs), composed of ordinary citizens, compared …

Do Sleep And Age Concurrently And Longitudinally Predict Children's Frustration Tolerance?, Mavery P. Allen

Senior Honors Theses and Projects

Frustration is experienced when there is interference with one’s goal or progress towards one’s goal. This study sought to examine how age and sleep affect child frustration through the observation of 2 experimental tasks, each a year apart. This study included data from 100 children (boys = 54) ages 3 to 5 years (M = 3.86) at Wave 1. There are 2 waves, occurring a year apart. The first task in Wave 1 consisted of giving a child keys to a locked, clear box with intriguing toys, but unbeknownst to them, the keys did not work. The second task consisted …

Integrating Computational Modeling And Experimental Analysis To Characterize Autophagosome Size And Number., Rakan A. Alnsour

Senior Honors Theses and Projects

Autophagy is a key cellular recycling process that helps cells maintain homeostasis and survive stress by breaking down damaged organelles and misfolded proteins. When autophagy is disrupted, it contributes to diseases such as cancer, Parkinson’s disease, and Alzheimer’s disease, so getting accurate measurements of autophagosome size and number is important for understanding how this pathway works. In this project, we are working on improving a computational model in CompuCell3D that simulates how autophagic bodies clump inside the yeast vacuole, which we later compare to real transmission electron microscopy images. We generated starting files with defined body numbers and sizes, simulated …

The Confidence-Man Goes To The Moving Panorama: Herman Melville’S Confidence Narrator And United States Imperialism, Bradley J. Lee

Graduate Theses/Dissertations

This thesis argues that Herman Melville fashioned his novel The Confidence-Man; His Masquerade (1857) after the moving panorama, a popular entertainment technology contemporary with the novel. More specifically, the thesis argues that the novel recalls Banvard’s Mississippi Panorama (1846). Using Jay Leyda’s The Melville Log and John Hanners’ record of Banvard’s performances, I establish beyond reasonable doubt the possibility that Melville saw this painting, or, at the very least, was aware of it, its content, and its social position. Tracing the novel’s engagement with this panorama reveals what seems at first to be its imperialist, Manifest Destinarian undertones. The novel’s …

Small Mammal Communities Within And Land Coverage Around Southwestern Missouri Prairies, Kaitlyn J. Bebensee

Graduate Theses/Dissertations

Land alterations can reduce the amount of suitable habitat necessary for persistence of an associated species. Within such constrained habitats, limited resources may elicit competition, which could cause shifts in abundance and occurrence of species. Missouri prairies have been declining in size, making it imperative to collect reference data on mammal populations within and land use types around remnants. For this study, I trapped small mammals in Southwestern Missouri prairies because they can be indicators of environmental health and can vary in abundance between prairies. I focus on the diet of two dominant small mammals, Peromyscus maniculatus and Microtus ochrogaster …

¡Salud! Sacrificing The Sacred Sip: A Critical Analysis Of The Impact Of The Spiritual Conquest On Alcohol Traditions In Central México, Elizabeth Vilchis

Graduate Theses/Dissertations

By thoroughly investigating the available primary sources, this thesis will convey the importance of the Mesoamerican inebriating drink pulque in both the ethos and mythos of ancient Nahua society, examining how the ritual use of pulque became problematic in the eyes of the Spaniards, by investigating the cultural and ideological contradictions or double standards that enabled the tensions, struggles, and violence with which the Spanish colonial regime repressed the ritual use of pulque. This thesis compares the Nahua ethos and mythos of pulque to the Christian ethos and mythos of wine, highlighting the parallels perceived by Spaniards in Central México …

Inherited Sins: Essays, Claire Ellerman

Graduate Theses/Dissertations

Joan Didion said of her book, The Year of Magical Thinking, that, “the reason I had to write it down, is that no one had ever told me what it was like.” She was trying to make sense of her grief following the death of her husband, and in doing so, wrote a piece of creative nonfiction (CNF) that explores her own life in and around the larger ideas of mourning, connection, and moving forward. This is the ultimate aim of creative nonfiction: writing to make sense of our lives in relation to the world around us. In this …

Gene Editing And The Accessibility Of Bioterrorism: Rethinking Global Biosecurity In The Post-Covid-19 Era, Nicholas Morales

Graduate Theses/Dissertations

COVID‑19 demonstrated how a single biological event can strain health systems, disrupt supply chains, undermine national security, and erode public trust. This shock occurred as biotechnology became dramatically more accessible: gene editing and synthetic biology tools once limited to specialized laboratories are now widely available through inexpensive equipment, open‑source data, and decentralized expertise.

This expanded access accelerates innovation but also broadens the threat landscape. The ability to reconstruct pathogens using publicly available sequences and mail‑order DNA shows that complex biological synthesis is no longer confined to state programs. These risks are amplified by opaque biotechnology activities in China, Russia, and …

Using 1:1 Behavior-Analytic Instruction To Enhance Outcomes Of A Social-Emotional Learning Curriculum: A Retrospective Single-Case Clinical Evaluation, Cierra Vandermeer

Graduate Theses/Dissertations

Social-Emotional Learning (SEL) is the process through which people acquire and apply skills to manage emotions, form relationships, make responsible decisions, and pursue personal and shared goals, and these competencies shape identity development and daily functioning (Collaborative for Academic, Social, and Emotional Learning [CASEL], 2020). While there are many SEL programs and curricula that exist for school-aged children, there are few curricula that a) have a focus on 1:1 instruction for preschool to primary-aged children, and b) integrate and incorporate Applied Behavior Analysis (ABA) principles. This thesis reviewed a retrospective case study of a six-year-old female-identifying student who participated in …

Scaling Private Remedies To Public Problems: A Resilient Property Theory Analysis, Marc L. Roark

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.

Near-Field Scan Method For Radiated Susceptibility Analysis And The Design And Optimization Of A Miniaturized Spiral Antenna For Ultra-Wideband Applications, Mckennan Edward Starkey

Masters Theses

"The work presented in this thesis consists of two separate topics. The first topic is a new method for the characterization of radiated susceptibility of electronic devices, while the second topic is on antenna design. The first topic proposes an approach to experimentally determine locations within an electronic system that are well coupled to external far-field radiators. This method is performed by using a differential magnetic field probe to sweep across the target device while measuring the total radiated power (TRP) produced by the device in a mode stirred tent. Scan locations where the TRP is larger than the background …

Castrip Process Technology: Non-Grain Oriented (Ngo) Si Steels Extension And Carbide-Free Bainitic (Cfb) For Flat Products, Naram Naidu Meesala

Masters Theses

"This research explores the development of advanced steel grades manufactured through Castrip® twin-roll thin strip casting technology, with particular attention to non-grain-oriented electrical Si-Steels (NGOES) and carbide-free bainitic (CFB) steels. The Castrip® process offers a near-net-shape route for producing thin steel strips, which greatly decreases the number of processing stages, lowers energy demand, and reduces carbon dioxide emissions when compared with traditional steel production methods.

In the NGOES part of the study, several industrial Fe–Si steel compositions were cold rolled to final thicknesses ranging from 0.35 mm to 0.15 mm. These materials were then exposed to short-duration continuous annealing at …

Validating A Low-Cost Radio Frequency Characterization Framework For Development-Grade Software-Defined Radios In Short-Duration Cubesat Missions, Thomas Wayne Francois

Masters Theses

Software-defined radios (SDRs) and CubeSat platforms have reduced the cost and complexity of space-based communication systems, enabling broader participation in satellite missions. While low-cost radio hardware is increasingly accessible, the ability to characterize and validate its performance remains constrained by the high cost and limited access to traditional RF test equipment. This disparity creates a challenge for small satellite development teams, which must characterize communication-system technical performance with limited access to laboratory-grade instrumentation.

This thesis presents a low-cost RF characterization framework for assessing key radio-frequency performance metrics using readily available hardware and measurement techniques. The approach integrates frequency translation, SDR-based …

When Speech Speaks Louder Than Truth: Language Variation And Credibility In The Courtroom, Melanie E. Spinnie

Graduate Theses/Dissertations

This study aims to investigate how linguistic variation affects perceptions of credibility in courtroom settings. It focuses on how jurors, judges, and other individuals in the legal system may exhibit bias (consciously or unconsciously) based on how a defendant or witness speaks-- this could include speech disorders as well as differences in dialect, accent, and speech style. Through review of relevant literature, review of a relevant historical case, conducting a survey, and conducting a semi-structured interview, this study explores whether certain speech patterns or characteristics are disproportionately associated with negative judgments during legal proceedings, such as reduced credibility and trustworthiness. …

Experimental Diegetic Thresholds: A Study Of Adapted Carceral Narratives [The] Nickel Boys And Sing Sing, Leslie D. Muench

Graduate Theses/Dissertations

The diegesis is the storyworld of a film, including all the characters, settings, events, and other elements. At certain times, though, that threshold is permeable, particularly when the fictional source material involves lived experiences. Two carceral films model an experimentation with adapted material and the palimpsestuous layering effect that is a result of real-life narratives being transposed into fictional ones. Nickel Boys, directed by RaMell Ross (2024), and Sing Sing, directed by Greg Kwedar (2023), endeavor to humanize a stereotypically ostracized community: Black boys and men who are incarcerated. Through the screenwriting, casting, producing, filming, and sharing of their films …

Europe In The Indo-Pacific - Implications For The United States, Joshua G. Zinicola

Graduate Theses/Dissertations

Within the last five years the Indo-Pacific has become a region of increasing interest to European NATO members. In particular, the United Kingdom, France, and Italy have assigned strategic importance for their national security to the region, signing cooperative agreements with regional allies of the United States and deploying significant forces to the region. These agreements include commitments to jointly develop new technologies and combat systems for employment in both Europe and the Indo-Pacific, such as the Global Combat Air Programme (GCAP), and the Trilateral security partnership between Australia, the United Kingdom, and the United States (AUKUS). They also include …

The Ones Who Watched: Technology, Proxy Warfare, And The Testing Ground Hypothesis, Sean J. Oliver

Graduate Theses/Dissertations

Great powers need laboratories for war. This thesis argues that great powers find these laboratories in proxy forces. Proxy warfare is not just a tool for strategic influence. It is a machine for experimentation. This study posits a central testing-ground hypothesis. It contends that great powers deliberately use surrogates to vet emerging technologies, doctrines, and mobilization schemes under the pressure of real combat. The analytical methodology is historical. It traces patterns from the ancient world's proxy forces and the innovations of the Crusades to the Cold War and the digital age. The thesis examines enduring patterns, including the tension between …