Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 40201 - 40230 of 1740687

Full-Text Articles in Entire DC Network

Prevention, Consultation, And Advocacy, Terrance Mcclellan Feb 2026

Prevention, Consultation, And Advocacy, Terrance Mcclellan

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

Goal Statement

My goal is to prevent depression among single mothers ages 20–30 in low-income areas of Southeast Missouri by expanding access to community-based emotional support, parenting resources, and skills training that strengthen coping and resilience.

Significant Findings

Young single mothers in Southeast Missouri, especially those in their twenties, often carry the emotional and financial weight of raising children on their own, which puts them at higher risk for long-term stress and depression when support is limited (Tafet & Nemeroff, 2016; NAMI Missouri, 2025). Many face persistent barriers such as high childcare costs, reduced access to mental health providers, transportation …


Doctrinal Intent Versus Institutional Reality: The Gulf Countries' Antitrust Objectives, Nora Memeti Feb 2026

Doctrinal Intent Versus Institutional Reality: The Gulf Countries' Antitrust Objectives, Nora Memeti

Yearbook of Antitrust and Regulatory Studies

This paper examines the intriguing contrast between the ambitious goals of antitrust laws in the Gulf countries and the reality of their enforcement. While this region seeks to protect competition and curb monopolistic practices, only Kuwait and the Kingdom of Saudi Arabia (KSA) have made significant strides in achieving these ideals.

Through a comparative legal analysis, this paper examines how the statutory objectives of competition law in Qatar, Bahrain, Oman, and the UAE often remain more rhetorical than substantive, with enforcement primarily symbolic. In contrast, Saudi Arabia demonstrates some enforcement activity, although its alignment with legislative objectives remains uncertain. Kuwait's …


The Parthenon, February 04, 2026, Baylee Parsons, Kaitlyn Fleming, Abby Ayes, Ella Hatfield, Davina Synder, Scott Price, Lilli Ross, Trista Honaker Feb 2026

The Parthenon, February 04, 2026, Baylee Parsons, Kaitlyn Fleming, Abby Ayes, Ella Hatfield, Davina Synder, Scott Price, Lilli Ross, Trista Honaker

The Parthenon

No abstract provided.


Protocol For Personalised Prediction Of Persistent Postsurgical Pain, Katherine J Holzer, Harutyun Alaverdyan, Ziqi Xu, Madelyn R Frumkin, Karen A Frey, Stephen H Gregory, Thomas L Rodebaugh, Chenyang Lu, Christopher R King, Denise Head, Thomas Kannampallil, Simon Haroutounian Feb 2026

Protocol For Personalised Prediction Of Persistent Postsurgical Pain, Katherine J Holzer, Harutyun Alaverdyan, Ziqi Xu, Madelyn R Frumkin, Karen A Frey, Stephen H Gregory, Thomas L Rodebaugh, Chenyang Lu, Christopher R King, Denise Head, Thomas Kannampallil, Simon Haroutounian

2020-Current year OA Pubs

INTRODUCTION: Persistent postsurgical pain (PPSP) affects up to 15% of patients after major surgery, impairing physical function, quality of life and increasing risk for long-term opioid use. Current PPSP prediction models rely on static or retrospective data and fail to incorporate dynamic perioperative factors. The Personalised Prediction of Persistent Postsurgical Pain (P5) study aims to develop individualised, multimodal prediction models by integrating preoperative behavioural, psychophysical and neurocognitive assessments and high-frequency symptom monitoring.

METHODS AND ANALYSIS: P5 is a prospective, single-centre cohort study enrolling 2500 adults aged 18-75 undergoing major surgery at a tertiary academic hospital. Participants complete baseline surveys, cognitive …


Multiparent Recombinant Inbred Lines Crossed To A Tester Provide Novel Insights Into Sources Of Cis And Trans Regulation Of Gene Expression, Patricka Williams-Simon, Paul Schmidt, Elizabeth King, Lauren M Mcintyre Feb 2026

Multiparent Recombinant Inbred Lines Crossed To A Tester Provide Novel Insights Into Sources Of Cis And Trans Regulation Of Gene Expression, Patricka Williams-Simon, Paul Schmidt, Elizabeth King, Lauren M Mcintyre

Faculty, Staff and Student Publications

To understand the relative importance of cis and trans effects on regulation, we crossed multi-parent recombinant-inbred lines (RILs) to a common tester and measured allele-specific gene expression in the offspring. Testing the difference of allelic imbalance between two RIL × Tester crosses is a test of cis or trans, depending on the RIL alleles compared. The study design also enables to separation of two sources of trans variation, genetic and environmental, detected via interactions with cis effects. We demonstrate the effectiveness of this approach in a long-read RNA-seq experiment in female abdominal tissue at two time points in Drosophila melanogaster. …


Associations Between Big Five Personality Traits, Facets, And Sexual Fantasies, Emily Cannoot, Amy C. Moors, Wiliam J. Chopik Feb 2026

Associations Between Big Five Personality Traits, Facets, And Sexual Fantasies, Emily Cannoot, Amy C. Moors, Wiliam J. Chopik

Psychology Faculty Articles and Research

The present study investigated associations between Big Five personality traits, their facets, and the frequency and variety of sexual fantasies in a sample of 5,225 adults (M = 58.30 years old; 56.5% men). People high in conscientiousness and agreeableness report fewer sexual fantasies across exploratory, intimate, impersonal, and sadomasochistic domains; these effects were primarily driven by respectfulness and responsibility facets. Negative emotionality, particularly the depression facet, was associated with more frequent sexual fantasizing. Extraversion and open-mindedness showed minimal relationships with sexual fantasy frequency. These results underscore the importance of personality dimensions in understanding sexual thoughts, emphasizing the heterogeneity of …


Infectious Causes Of Acute Febrile Illness In Belize, 2020-2022, Roberto Melendez, Sarah M Gunter, Allison Lino, Joy Mackey, Andres Espinosa-Bode, Beatriz Lopez, Rafael Chacon-Fuentes, Freedom M Green, Oluwadara Okeremi, Sarah Strobel, Daniel P Rehm, Flor M Muñoz, Loren Cadena, Melissa Diaz-Musa, Francis Morey, Emily Zielinski-Gutierrez, Gerhaldine Morazan, Kristy O Murray Feb 2026

Infectious Causes Of Acute Febrile Illness In Belize, 2020-2022, Roberto Melendez, Sarah M Gunter, Allison Lino, Joy Mackey, Andres Espinosa-Bode, Beatriz Lopez, Rafael Chacon-Fuentes, Freedom M Green, Oluwadara Okeremi, Sarah Strobel, Daniel P Rehm, Flor M Muñoz, Loren Cadena, Melissa Diaz-Musa, Francis Morey, Emily Zielinski-Gutierrez, Gerhaldine Morazan, Kristy O Murray

Faculty, Staff and Students Publications

Acute febrile illness (AFI) surveillance networks can play a key role in identifying emerging pathogens and promoting global health security, especially for vulnerable populations in low- and middle-income countries. In January 2020, the Belize AFI Surveillance network was formed, and 5,643 participants were enrolled over the first 3-year period across 11 participating public hospitals. Using real-time polymerase chain reaction testing for vector-borne pathogen detection and BioFire® diagnostic testing for respiratory and gastrointestinal pathogens, the causes of illness were examined in relation to 54 pathogens in these participants. In response to the coronavirus disease 2019 pandemic, surveillance was expanded to detect …


Social, Environmental And Policy Contexts Affecting The Feasibility And Acceptability Of Improving Household Flooring For Better Health In Rural Kenya, Ulrike Fillinger, Victoria A. Ochwal, Hugo Legge, Sharon Muli, Karisa Kazungu, Carlos Mcharo, Jacinta Mwongeli, Charles Mwandawiro, Katherine Halliday, Doris Njomo, Rachel Pullan, Lynne Elson, Stella Kepha Feb 2026

Social, Environmental And Policy Contexts Affecting The Feasibility And Acceptability Of Improving Household Flooring For Better Health In Rural Kenya, Ulrike Fillinger, Victoria A. Ochwal, Hugo Legge, Sharon Muli, Karisa Kazungu, Carlos Mcharo, Jacinta Mwongeli, Charles Mwandawiro, Katherine Halliday, Doris Njomo, Rachel Pullan, Lynne Elson, Stella Kepha

All Peer-Reviewed Publications

BACKGROUND: Homes with unimproved floors (earth, sand, or clay) are associated with increased risks of soil-transmitted parasites and enteric infections, leading to higher morbidity and reduced quality of life. This study explored the enablers and barriers to adopting improved flooring (sealed, washable, and durable) in three culturally diverse regions of Kenya - Narok, Bungoma, and Kwale - to mitigate disease burdens. METHODS: Between August 2021 and July 2022, we conducted 24 focus group discussions with homeowners, stratified by age, gender, and floor type. Additionally, 28 key informant interviews with local government officials, microfinance representatives, and masonry trainers in Kwale and …


Staff Education Project To Improve Hypertension Medication Adherence In An Underserved Clinic, Margaret Mboe Etukeni Feb 2026

Staff Education Project To Improve Hypertension Medication Adherence In An Underserved Clinic, Margaret Mboe Etukeni

Walden Dissertations and Doctoral Studies

Hypertension is one of the most common chronic conditions managed in primary care. The identified practice problem for this staff education project was the lack of structured staff training and inconsistent provider knowledge regarding evidence-based strategies to improve medication adherence among patients with hypertension. Poor medication contributes to preventable complications such as stroke, heart failure, and kidney disease. The purpose was to evaluate if an educational intervention could improve provider knowledge related to medication adherence strategies in an underserved clinical setting. The practice question guiding the project was: In clinical staff working in an underserved clinic, does a staff education …


Multimodal Education To Improve Metabolic Monitoring Knowledge Among Psychiatric Nurse Practitioners, Tania Alfonso Feb 2026

Multimodal Education To Improve Metabolic Monitoring Knowledge Among Psychiatric Nurse Practitioners, Tania Alfonso

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) staff education project was a multimodal educational intervention to improve outpatient psychiatric nurse practitioner (PNP) knowledge of metabolic monitoring guidelines for patients prescribed second-generation antipsychotics (SGAs). The project addressed low adherence to national monitoring standards that contribute to increased cardiometabolic risks associated with SGAs. The project question was: Does staff education regarding metabolic monitoring guidelines improve nursing knowledge as compared pre- to posteducation? The purpose was to enhance PNP knowledge of metabolic monitoring guidelines. Guided by the Johns Hopkins evidence-based practice (JHEBP) model, I conducted a focused literature search and identified 28 peer-reviewed articles …


Key Strategies To Entrepreneurial Sustainability In The Information And Communications Industry, Agabi Godwin Onugba Feb 2026

Key Strategies To Entrepreneurial Sustainability In The Information And Communications Industry, Agabi Godwin Onugba

Walden Dissertations and Doctoral Studies

Many businesses in the information and communications industry fail within the first 5 years, yet the existing empirical research has not sufficiently explained how surviving businesses achieve long-term sustainability. Startup business leaders are concerned about the high failure rate and the lack of evidence-based strategies that support sustained operations beyond 5 years. Grounded in Porter’s five forces theory, the purpose of this qualitative pragmatic inquiry project was to identify and explore successful strategies that information and communications industry startup business leaders use for long-term business sustainability beyond 5 years. Purposeful sampling was employed to select six startup leaders in the …


Staff Education On Implementing Exercise For The Management Of Depression In Adults In A Comprehensive Mental Health Facility, Afolasade Jarrett Feb 2026

Staff Education On Implementing Exercise For The Management Of Depression In Adults In A Comprehensive Mental Health Facility, Afolasade Jarrett

Walden Dissertations and Doctoral Studies

In a comprehensive mental health facility, patients diagnosed with major depression continue to experience depressive symptoms despite treatment. Despite using standard treatment with antidepressants and psychotherapy, facility data showed that 40% of these patients are still experiencing depression symptoms that negatively impact their overall functioning and quality of life. There is evidence supporting exercise as an effective strategy for depression treatment. Therefore, a staff education project was proposed to educate staff about exercise for depression management in adults. A thorough literature search in four databases yielded 12 articles with high quality evidence supporting educating staff to use exercise for depression …


Engaging Clinical Teams Through Leadership, Workplace Culture, And Job Satisfaction, Garidanielle Matsey Feb 2026

Engaging Clinical Teams Through Leadership, Workplace Culture, And Job Satisfaction, Garidanielle Matsey

Walden Dissertations and Doctoral Studies

Current literature does not adequately address the factors that lead to and prevent burnout and poor work performance among inexperienced clinicians and clinical supervisors working in group private practice. Exploring supervision experiences, specifically leadership style, employee engagement, and internal communication, may provide insight into the experiences of novice mental health professionals and their supervisors in addressing burnout and enhancing work performance. Through a qualitative single-case study design informed by interpretative phenomenological principles, data were collected in semistructured interviews with five behavioral health leaders from a two-location group private practice who hold dual roles as clinicians and supervisors. The interview data …


Staff Education On Standardized Appointment Reminder & Follow-Up Protocol, Sambila V. Zangre Congo Feb 2026

Staff Education On Standardized Appointment Reminder & Follow-Up Protocol, Sambila V. Zangre Congo

Walden Dissertations and Doctoral Studies

Inconsistent staff performance in making appointment reminders and follow-up calls contributed to workflow variability and reduced patient engagement in outpatient primary care settings. This DNP Quality Improvement Project intended to enhance staff knowledge, confidence, and consistency in implementing standardized reminder and follow-up call protocols using an evidence-based educational intervention. A quantitative pre/posttest design was used to evaluate changes in staff competency, supported by descriptive and comparative analyses of test scores, percentage changes, and qualitative feedback. Seven clinic staff members attended the PowerPoint education session, and pretest and posttest data were used to address a practice-focused question about standardized communication workflows. …


Staff Education To Clinical Staff Within An Outpatient Psychiatric Practice, Ivy Dzifa Dzivenu Feb 2026

Staff Education To Clinical Staff Within An Outpatient Psychiatric Practice, Ivy Dzifa Dzivenu

Walden Dissertations and Doctoral Studies

No abstract provided.


Relationship Between Perceived Leadership Styles And Millennial Membership Growth In Nonprofit Churches, Larry Latham Feb 2026

Relationship Between Perceived Leadership Styles And Millennial Membership Growth In Nonprofit Churches, Larry Latham

Walden Dissertations and Doctoral Studies

Despite the widespread decline in church membership and attendance among all mainline denominations, there was a particular concern about retaining the millennial generation. Church leaders need to understand this concern as a key indicator of millennial retention in nonprofit churches. The purpose of this quantitative study was to examine the relationship between millennial membership growth and perceived leadership styles, including authoritative, partnership, democratic, team oriented, relationship oriented, serving, people oriented, task oriented, and goal oriented leadership. The social exchange theory and resource-based view theory grounded this study. The archival data from 2011 to 2022 comprised 17,012 Millennial participants from 665 …


Staff Education To Enhance Nursing Knowledge Of Central Line-Associated Bloodstream Infection Prevention Bundles On A Solid Organ Transplant Unit, Amina Cole-Kangbai Feb 2026

Staff Education To Enhance Nursing Knowledge Of Central Line-Associated Bloodstream Infection Prevention Bundles On A Solid Organ Transplant Unit, Amina Cole-Kangbai

Walden Dissertations and Doctoral Studies

I conducted this staff education quality improvement project to develop and implement an education program addressing nurses’ knowledge gaps on evidence-based, central line-associated bloodstream infection (CLABSI) prevention bundles on a solid organ transplant unit. CLABSIs are preventable infections disproportionately affecting immunocompromised transplant patients, increasing morbidity, mortality, and costs. Addressing this issue is critical because nurses provide frontline central line care, and their knowledge directly influences patient safety.


Staff Education On Vital Sign Assessment And Electronic Health Record Documentation For Acute And Critical Care Nurses And Patient Care Technicians, Natalie Brock Feb 2026

Staff Education On Vital Sign Assessment And Electronic Health Record Documentation For Acute And Critical Care Nurses And Patient Care Technicians, Natalie Brock

Walden Dissertations and Doctoral Studies

A staff educational quality improvement initiative aimed at enhancing the knowledge and accuracy of acute care nurses and patient care technicians (PCTs) in vital sign documentation was the focus of the doctoral project. Gaps in vital sign obtainment and electronic health record (EHR) documentation were identified through organizational serious safety event reviews, highlighting risks to patient safety and clinical decision-making. The project addressed the question of whether, in the inpatient hospital setting, a staff educational training program for acute and critical care nurses improves their knowledge of accurate vital sign documentation in the EHR. I analyzed pre- and posttest assessments …


Improving Follow-Up And Continuity Of Care Protocols Through Staff Education In An Outpatient Mental Health Clinic, Bimpe Omobolade Adedo Feb 2026

Improving Follow-Up And Continuity Of Care Protocols Through Staff Education In An Outpatient Mental Health Clinic, Bimpe Omobolade Adedo

Walden Dissertations and Doctoral Studies

In this DNP staff education project, I aimed to solve two main issues which disrupted patient treatment continuity: better documentation and follow-up care practices. The existing gaps in knowledge have led to missing scheduled appointments, missing medical information, and weak communication between hospital staff and clinic staff resulting in disorganized patient care. The main goal of the project was to improve staff understanding of post treatment procedures, maintenance systems, and medical recordkeeping requirements. Ten clinical staff members participated in education. Pre- and post-knowledge assessments were used to evaluate knowledge change. The normalized learning gain formula served to measure the extent …


Education To Nursing Staff On Evidence-Based Lifestyle Interventions For Hypertension, Meagan Deese Feb 2026

Education To Nursing Staff On Evidence-Based Lifestyle Interventions For Hypertension, Meagan Deese

Walden Dissertations and Doctoral Studies

This Doctor of Nursing Practice (DNP) project was a staff education project that addressed a practice gap in a primary care setting related to limited nursing knowledge of evidence-based lifestyle interventions for hypertension management. Hypertension is a prevalent chronic condition and a major contributor to cardiovascular morbidity and mortality. Although clinical guidelines recommend lifestyle modification as first-line management, nurses may receive limited formal training in nonpharmacologic interventions. The practice-focused question was, in a primary care setting, does a nursing education program on evidence-based lifestyle interventions for hypertension improve nursing knowledge as measured pre- to post education? The purpose of the …


Perceptions Of Community College Faculty Regarding Online Student Engagement Challenges And Recommendations, Jana Allen-Bishop Feb 2026

Perceptions Of Community College Faculty Regarding Online Student Engagement Challenges And Recommendations, Jana Allen-Bishop

Walden Dissertations and Doctoral Studies

The problem addressed through this study is that local community college faculty members struggle to develop student engagement in online courses. The purpose of this basic qualitative study was to explore community college faculty perceptions about challenges with student engagement in online courses and recommendations for fostering that engagement. The conceptual frameworks for this study were Knowles’ theory of andragogy and self-directed learning, as well as Mezirow’s transformative learning theory. Data were collected through semistructured interviews with eight community college faculty members teaching online courses. Through open and axial coding the following themes emerged: faculty noted that their own technological …


Passed Down Like Prayer: The Burden And Inheritance Of The Superwoman Schema, Keyishi Shante Peters Feb 2026

Passed Down Like Prayer: The Burden And Inheritance Of The Superwoman Schema, Keyishi Shante Peters

Tennessee State University Alumni Theses and Dissertations

This qualitative phenomenological study examined how Black Baby Boomer and Millennial women perceive and internalize the Superwoman Schema (SWS), a cultural expectation emphasizing strength, emotional restraint, and self-sacrifice. Grounded in Black feminist thought, the analysis explored how the SWS is passed down like prayer, quietly inherited, spiritually charged, and embedded in the everyday practices of survival. Four themes emerged: Being Everything to Everybody, Carrying It All Until It Breaks You, We Were Taught Not to Say No, and Learning to Put the Cape Down. Baby Boomers often described the SWS as a necessary legacy forged through historical struggle, while Millennials …


Time Trends In The Male To Female Ratio For Autism Incidence: Population Based, Prospectively Collected, Birth Cohort Study, Caroline Fyfe, Henric Winell, Joseph Dougherty, David H Gutmann, Alexander Kolevzon, Natasha Marrus, Kristina Tedroff, Tychele N Turner, Lauren A Weiss, Benjamin H K Yip, Weiyao Yin, Sven Sandin Feb 2026

Time Trends In The Male To Female Ratio For Autism Incidence: Population Based, Prospectively Collected, Birth Cohort Study, Caroline Fyfe, Henric Winell, Joseph Dougherty, David H Gutmann, Alexander Kolevzon, Natasha Marrus, Kristina Tedroff, Tychele N Turner, Lauren A Weiss, Benjamin H K Yip, Weiyao Yin, Sven Sandin

2020-Current year OA Pubs

OBJECTIVES: To examine changes in the male to female ratio in diagnoses of autism spectrum disorder (ASD) over a 35 year period, providing temporal trends in diagnosis (incidence rate), the male to female ratio, and the age-cohort specific cumulative male to female ratio (cMFR).

DESIGN: Population based, prospectively collected birth cohort study.

PARTICIPANTS: 2 756 779 liveborn children recorded in the Swedish medical birth register between 1985 and 2020.

SETTING: Sweden.

MAIN OUTCOME MEASURE: Age-period cohort analysis investigating associations between ASD and age at diagnosis, calendar period, birth cohort, and sex, quantified by incidence rate ratios and associated two sided …


Spartan Daily, February 4, 2026, San Jose State University, School Of Journalism And Mass Communications Feb 2026

Spartan Daily, February 4, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 6


Seeing Beyond The Words: What Interdisciplinary Methodologies Reveal About International Law, Matthew S. Erie, Mark Pollack, Wolfgang Alschner, Beth Simmons, Katerina Linos Feb 2026

Seeing Beyond The Words: What Interdisciplinary Methodologies Reveal About International Law, Matthew S. Erie, Mark Pollack, Wolfgang Alschner, Beth Simmons, Katerina Linos

Scholarly Articles in Law Reviews & Journals

INTRODUCTION: On April 24, 2025, the International Law and Social Science Interest Group debuted at the ASIL Annual Meeting with a panel that posed a deceptively simple question: how can social science tools advance the work of international lawyers? Chaired by Chantal Thomas, the session brought together Matthew Erie, Wolfgang Alschner, Beth Simmons, and Katerina Linos— scholars who bridge doctrinal and empirical inquiry—to show how ethnography, computational text analysis, counterfactual inference, and mixed-method design can illuminate legal puzzles that doctrine alone cannot solve. The four short essays in this symposium provide parallel illustrations of this core theme: Erie’s ethnographic approach …


Repurposing Of The Macrolide Antibiotic Clarithromycin For The Prevention Of Lung Cancer, Shanshan Deng, Tabish Hussain, Thais F Bartelli, Manu M Sebastian, Melody Zarghooni, Brandon Somerville, Michelle I Savage, Yurong Song, John L Clifford, Humam Kadara, Florencia Mcallister, Powel H Brown, Seyed Javad Moghaddam, C Marcelo Aldaz Feb 2026

Repurposing Of The Macrolide Antibiotic Clarithromycin For The Prevention Of Lung Cancer, Shanshan Deng, Tabish Hussain, Thais F Bartelli, Manu M Sebastian, Melody Zarghooni, Brandon Somerville, Michelle I Savage, Yurong Song, John L Clifford, Humam Kadara, Florencia Mcallister, Powel H Brown, Seyed Javad Moghaddam, C Marcelo Aldaz

Faculty, Staff and Student Publications

Drug repurposing is the process of reusing existing pharmaceuticals for novel clinical purposes, which offers advantages such as streamlined clinical trial access and reduced drug development costs. Clarithromycin (CAM), a member of the macrolide antibiotics family, is a promising candidate for repurposing in cancer therapy due to its known preclinical and clinical immunomodulatory and anticancer properties. In the current study, we investigated whether CAM could be repurposed as a preventive treatment for KRAS-mutant lung cancer, a subtype of lung adenocarcinoma that is strongly associated with heavy smoking. CCSPCre; LSL-KrasG12D mice at an early stage of tumor development were treated with …


Tumor Radiosensitization With Gold Nanoparticles: Evolving Strategies To Improve Tumoral Gold Uptake And Catalyze Future Clinical Translation, Prapannajeet Biswal, Geraldine V Vijay, Gabrielle Krouse, Phuoc Minh Quan Mai, Bhoomika Muruvekere Lakshmisha, Mahdieh Yousefi Taba, Lydia Wt Cheung, Yuri Mackeyev, Khadijeh Koushki, Sunil Krishnan Feb 2026

Tumor Radiosensitization With Gold Nanoparticles: Evolving Strategies To Improve Tumoral Gold Uptake And Catalyze Future Clinical Translation, Prapannajeet Biswal, Geraldine V Vijay, Gabrielle Krouse, Phuoc Minh Quan Mai, Bhoomika Muruvekere Lakshmisha, Mahdieh Yousefi Taba, Lydia Wt Cheung, Yuri Mackeyev, Khadijeh Koushki, Sunil Krishnan

Faculty, Staff and Student Publications

Radiation therapy is integral to the treatment regimens of over 50% of cancer patients. However, it is not biologically targeted to just the tumor, leading to adverse effects in peritumoral normal tissue. Selective uptake of gold nanoparticles (AuNPs) by tumors realizes tumor-specific radiosensitization via increased secondary electron release from high atomic number gold atoms. Here, we review AuNP-mediated radiosensitization and outline strategies to optimize tumor-targeted AuNP delivery. Modifying the physicochemical characteristics of AuNPs, including size, shape, charge, and surface chemistry, can increase their ability to evade the reticuloendothelial system (RES) and penetrate the dense tumor stromal architecture, thereby promoting tumor …


A Case Of Dislocation And Successful Reduction Of A Right Anterior Shoulder Inside A Space Suit: Considerations For Future Protocols, Brandon Trapp Feb 2026

A Case Of Dislocation And Successful Reduction Of A Right Anterior Shoulder Inside A Space Suit: Considerations For Future Protocols, Brandon Trapp

Faculty, Staff and Student Publications

Shoulder dislocations are prevalent on Earth and pose unique challenges in spaceflight and spaceflight training, particularly during extravehicular activities (EVAs). This case report describes a 50-year-old male who experienced an anterior shoulder dislocation while performing an emergency egress exercise in a SpaceX EVA suit. The report describes the medical thought process, the operational constraints, and the reduction techniques employed to achieve a successful shoulder reduction without fully removing or damaging the suit. NASA estimates a high likelihood of shoulder injuries during long-duration lunar missions, emphasizing the importance of suit designs and rescue protocols. Quick and effective medical intervention is crucial, …


Geochemical Fate Of Lead In Contaminated Residential Soils Following Application Of Amendments For Lead Immobilization, Hadeer Saleh, Washington Braida, Zhiming Zhang, Rupali Datta, Dibyendu Sarkar Feb 2026

Geochemical Fate Of Lead In Contaminated Residential Soils Following Application Of Amendments For Lead Immobilization, Hadeer Saleh, Washington Braida, Zhiming Zhang, Rupali Datta, Dibyendu Sarkar

Michigan Tech Publications

Background: Lead (Pb) persists in urban soils, where its partitioning among geochemical fractions governs mobility, bioavailability, and human health risk. These fractions are strongly controlled by soil physicochemical properties, necessitating site-specific remediation strategies. Methods: This study developed a site-specific Pb immobilization framework linking amendment selection to soil geochemistry and sustainability considerations. Pb-contaminated residential soils from three U.S. cities, San Antonio (alkaline), Baltimore (acidic), and Detroit (near-neutral), were treated with gypsum, biochar + lime, and alum, respectively. Changes in Pb speciation were tracked using sequential extraction over 7, 30, and 90 days. Results: All amendments significantly reduced exchangeable Pb (F1) and …


Competitive Advantage Strategies For Independent Restaurant Owners, Bobby Mccrary Feb 2026

Competitive Advantage Strategies For Independent Restaurant Owners, Bobby Mccrary

Walden Dissertations and Doctoral Studies

Independent restaurant owners often face challenges in achieving a sustainable competitive advantage, resulting in poor business performance and loss of profitability. Identifying practical competitive advantage strategies is essential for independent restaurant owners to surpass five years of business operations. Grounded in resource-based view theory, the purpose of this multiple case study was to explore effective competitive advantage strategies independent restaurant owners used to sustain operations beyond five years. Purposeful sampling was used to select four independent restaurant owners located in Wichita, Kansas, who sustained operations beyond five years through competitive advantage strategies. Data were collected from semistructured interviews and from …