Digital Commons Network^™

Managing Acute Myocardial Infarction In Remote Oman: Real-World Data From Al Wusta Governorate, Thuraiya Malik Abdullah Al Harthi, Ibrahim Al Mahrouqi, Amin Elbanna, Karema Hamed, Mohammed Abushilla, Venkatesh Kumar, Maryam Al Nabhani, Hasina Al Harthi, Abdulmunim Al Farsi, Adil Al Mahrouqi

Sultan Qaboos University Medical Journal

Objectives: Acute ST-segment elevation myocardial infarction (STEMI) is a time-sensitive cardiac emergency requiring prompt reperfusion therapy. Management and outcomes in remote areas are underexplored. This study explored the STEMI reperfusion network in Al Wusta governorate in Oman and evaluated the effectiveness of pharmacological thrombolysis in general practitioner (GP)-led, resource-limited hospitals. Methods: This retrospective study reviewed administrative health registries and medical records of patients presenting with STEMI to hospitals in the Al Wusta governorate between June 2017 and December 2024. Response to thrombolysis was defined as 50% resolution of ST-segment on electrocardiogram. Outcomes post-thrombolysis were prespecified. Multivariate logistic regression was used …

Financial Stability Success Strategies For Nursing Homes, Jennifer Helene Garrison

Walden Dissertations and Doctoral Studies

Ineffective regulatory strategies can lead to reduced financial stability. Nursing home leaders who wrestle to improve regulatory practices may find their business facing reduced financial sustainability. Grounded in management by objectives theory, the purpose of this qualitative pragmatic inquiry research project was to identify and explore the effective strategies nursing home leaders used to implement regulatory compliance practices that increase financial sustainability. The participants were nine nursing home leaders who had successfully implemented regulatory compliance strategies within their organizations. Data was collected through semistructured interviews, public websites, and current and archival public documents. Through thematic analysis, three themes were identified: …

Syndecan-1-Targeted Therapeutic Antibody Impairs Macropinocytosis And Elicits Antitumor Immunity In Pancreatic Cancer, Zecheng Yang, Madelaine S Theardy, Shuaitong Chen, Yongkun Wei, Mitsunobu Takeda, Yue Zeng, Xiaofei Wang, Jun Yao, Jennifer Li, Prapassorn Thirasastr, Jangho Park, Yangxi Zheng, Long T Vien, Khalida M Wani, Huamin Wang, Sisi Gao, Tim Heffernan, Lawrence Kwong, Ignacio I Wistuba, Laura Bover, Giulio F Draetta, Haoqiang Ying, Wantong Yao

Faculty, Staff and Student Publications

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies, with a 5-year survival rate of just 13%. While the development and early clinical use of small molecules targeting oncogenic KRAS mutations, key drivers of PDAC, have shown promise, resistance to these targeted therapies remains a significant challenge. We recently identified Syndecan-1 (SDC1), a highly expressed heparan sulfate proteoglycan, as a critical KRAS effector protein that promotes nutrient salvage and tumor growth. Here, we report the development of a human-specific monoclonal antibody (anti-SDC1 mAb) that inhibits PDAC cell proliferation in vitro and suppresses PDAC tumor growth in vivo. Mechanistically, …

Exploring K–12 Teacher Motivation To Engage With Ai In Education, Ethel Tshukudu, Katharine Childs, Gaokgakala Alogeng, Emma R. Dodoo, Douglas R. Case, Tebogo Videlmah Molebatsi

Faculty Research, Scholarly, and Creative Activity

While global interest in K–12 AI and ML education grows, many African education systems lack foundational computing education beyond basic computer literacy. This creates unique challenges for AI integration in countries where computer science isn’t part of the K–12 curriculum. Teachers are central to this effort, but little is known about what motivates them to engage with these technologies or how they use them. This study examined what motivates K–12 teachers to engage with AI and ML in Botswana. Using a mixed-methods approach, we surveyed 59 teachers using an adapted version of the Motivation to Teach Computer Science (MTCS) scale …

Satellites, Urban Heat, And Environmental Justice: Community As The Bridge Between Analysis And Action, Joshua B. Fisher, Ambar Rivera, Ava Cison, Ashley Agatep, Kainani Tacazon, Sophia Spiegleman, Alison Mckenery, Rio E. Fisher, Reginald Archer, Jason A. Douglas

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Heat waves are increasing in frequency, intensity, magnitude, and duration, causing a disproportionate impact on marginalized communities exposed to urban heat islands. Newly emerging spaceborne thermal sensing instruments, such as ECOSTRESS and Hydrosat, now have the capabilities to measure urban surface temperatures accurately at the block level (< 100 m) and with enough frequency to capture transient heat waves (daily to subweekly). Such data are critical for monitoring and informing policy and mitigation efforts, such as resurfacing, green space, cooling stations, and medical mobilization. These serve to advance environmental justice and reduce health risks—and deaths—among the most vulnerable: minority, low-income, elderly, those with physical- and mental-health preconditions, unhoused, children, and outdoor workers. While scientists have increasingly used satellite data to quantify urban heat islands and risks to communities, there remains a significant gap in action resulting from such analyses—a figurative and literal “valley of death.” Reviewing over 500 scientific publications, we identify a critical lack of engagement with the communities being analyzed (10.9%; n = 58); yet, community engagement is key to bridging such analysis with subsequent action. Here, we demonstrate how participatory community engagement directly with data and analysis leads to increased policy changes and mitigation efforts. Our framework has immediate implications for how scientists may augment their work and thought processes to achieve …

A Photosynthetic–Respiratory Electron Transport Chain Chimera Based On Photosystem I And Cytochrome C Oxidase On Graphene Oxide, Xiaoping Zhu, Matthew J. Kummer, Carolyn E. Lubner, Vasily Kurashov, William Carr, John H. Golbeck, Robert A. Niederman, Lev G. Mourokh, Shelley D. Minteer, Paul G. Falkowski, Michele Vittadello

Chemistry Faculty Research & Creative Works

Te self-assembly of enzyme proteins on 2D nanomaterials has enabled the construction and functional control of viable biochemical pathways. However, enzymatic cascades, which combine essential components of the photosynthetic and respiratory electron transport chains in tandem, have thus-far remained elusive. Herein, we have investigated a galvanic biohybrid nano system coupling photosystem I and cytochrome c oxidase on the surface of graphene oxide nanosheets in colloidal suspension. Te oriented immobilization of the enzymes was facilitated by Ni-coordination sites tethered to the carbon basal plane, with negligible parasitic O2 consumption. Transient absorption and electrochemical measurements provided evidence of electron transfer between donors …

General Anesthesia Versus Conscious Sedation For Mechanical Thrombectomy In Patients With Acute Ischemic Stroke In The Most Trial, Umeshkumar Athiraman, Akash Roy, Andrew Barreto, Joseph Broderick, Colin Derdeyn, Jordan Elm, James C Grotta, James Ingles, Achala Vagal, Max Wintermark, Opeolu Adeoye

2020-Current year OA Pubs

BACKGROUND: Several observational studies have supported the use of conscious sedation (CS) for endovascular thrombectomy in patients with acute ischemic stroke and associated general anesthesia (GA) with poor functional outcomes. Recently, few randomized controlled trials have shown no difference in the functional outcomes between GA and CS. The aim of this paper is to compare the outcomes of GA versus CS in patients with acute ischemic stroke undergoing mechanical thrombectomy in the MOST (Multi-arm Optimization of Stroke Thrombolysis) trial.

METHODS: Patients who underwent mechanical thrombectomy for acute ischemic stroke under GA or CS in the MOST trial were included. The …

Contemporary Philosophical Proposals For The University, Seth Vanetta

Dewey Studies

No abstract provided.

John Dewey Studies In Central Europe: Eli Kramer Interviews Emil Visnovsky, Emil Visnovsky, Eli Kramer

Dewey Studies

No abstract provided.

Evaluating Public Philosophy In Higher Education: Lessons Learned Baking Philosophical Bread, Anthony Cashio, Eric Thomas Weber

Dewey Studies

No abstract provided.

Taking It To The People: Translating Empirical Findings About Black Men And Black Families Through A Black Public Philosophy, Tommy J. Curry, Gwenetta D. Curry

Dewey Studies

No abstract provided.

Philosopher-As-Laison? Lessons From Sustainable Knowledge And American Philosophy, Danielle Lake, Paul Thompson

Dewey Studies

No abstract provided.

Editor's Introduction, Leonard J. Waks

Dewey Studies

No abstract provided.

Front Matter And Table Of Contents, Dewey Studies

Dewey Studies

No abstract provided.

The Relationship Between Mindful Awareness And Acculturative Stress For International Undergraduate Students In America, Nandini Narula Bajpai, Mary Stone

International Journal of Undergraduate Research and Creative Activities

This study examines mindful awareness and its role in acculturative stress experienced by international undergraduate students in American colleges. Data from 101 students from 37 countries attending 35 colleges revealed a significant negative correlation between mindful awareness and acculturative stress (r[99] = -0.51, p < 0.001). Higher mindful awareness predicted lower general acculturative stress and specific subdomains. These findings aim to refine cultural adaptation frameworks and inform evidence-based support systems for international students.

Research Note: Understanding Dewey's Connection To China--A Bibliography On Selected Works, James Zhi Yang

Dewey Studies

No abstract provided.

The Problem Of Nihilism: A Personal Journey From Nietzsche To Dewey, Jim Garrison

Dewey Studies

No abstract provided.

Pragmatizing Critical Theory's Province, Roberto Frega

Dewey Studies

No abstract provided.

Editor's Introduction, Leonard J. Waks

Dewey Studies

No abstract provided.

Front Matter And Table Of Contents, Dewey Studies

Dewey Studies

No abstract provided.

The Mind Is Not The Brain: John Dewey, Neuroscience, And Avoiding The Mereological Fallacy, Deron Boyles

Dewey Studies

No abstract provided.

The "Dewey Lippman Debate" And The Role Of Democratic Communication On The Trump Age, Lance E. Mason

Dewey Studies

No abstract provided.

The Nature Philosophy Of John Dewey, John R. Shook

Dewey Studies

No abstract provided.

Editor's Introduction, Leonard Waks

Dewey Studies

No abstract provided.

Introduction To Dewey Studies, Jim Garrison

Dewey Studies

No abstract provided.

Front Matter And Table Of Contents, Dewey Studies

Dewey Studies

No abstract provided.

An Analysis Of Gregorio’S Vox Article: Bridging The Gap Between Scientists And The Public, Nicole Gregorio

Fresh Voices: Composition at Cal Poly

No abstract provided.

Talking About Science Could Be The Key To A Brighter Future, Nicole Gregorio

Fresh Voices: Composition at Cal Poly

No abstract provided.

The Poisoning Of Flint’S People, Vanessa Lamoureux

Fresh Voices: Composition at Cal Poly

No abstract provided.

Women In Stem Fields, Jenna Riegel

Fresh Voices: Composition at Cal Poly

No abstract provided.