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Articles 36031 - 36060 of 1736520

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Remodeling Of The Mouse Liver And Skeletal Muscle Metabolome In Response To Continuous Acute Exercise And Disruption Of Ampk-Glycogen Interactions, Mehdi R. Belhaj, David I. Broadhurst, Thomas Dignan, Jamie Whitfield, Lisa Murray-Segal, Naomi X.Y. Ling, Jonathan S. Oakhill, Bruce E. Kemp, John A. Hawley, Stacey N. Reinke, Nolan J. Hoffman Mar 2026

Remodeling Of The Mouse Liver And Skeletal Muscle Metabolome In Response To Continuous Acute Exercise And Disruption Of Ampk-Glycogen Interactions, Mehdi R. Belhaj, David I. Broadhurst, Thomas Dignan, Jamie Whitfield, Lisa Murray-Segal, Naomi X.Y. Ling, Jonathan S. Oakhill, Bruce E. Kemp, John A. Hawley, Stacey N. Reinke, Nolan J. Hoffman

Research outputs 2022 to 2026

Background/Objectives: Acute exercise remodels many interconnected biochemical pathways in metabolically active tissues. This remodeling involves the activation of the energy-sensing AMP-activated protein kinase (AMPK) to maintain cellular energy homeostasis. Critical energy reserves of glycogen, primarily stored in liver and skeletal muscle and known to interact with AMPK, are utilized to help meet increased energy demands with exercise. However, the breadth of metabolic pathways regulated by acute exercise and AMPK’s interactive roles with glycogen remain incompletely understood. This study therefore aimed to map mouse liver and skeletal muscle metabolite responses to continuous acute exercise and disruption of AMPK-glycogen interactions. Methods: Liquid …

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Seeing Voices: A Dynamic, Interprofessional Approach To Teaching Performing Arts And Speech-Language Pathology Students About Vocal Anatomy And Physiology, Deborah Hersh, Luzita Fereday, Fiona Palmer, David Hall, Pedro Amarante Andrade, Priscilla Cornelius, Charn Nang, Jane White Mar 2026

Seeing Voices: A Dynamic, Interprofessional Approach To Teaching Performing Arts And Speech-Language Pathology Students About Vocal Anatomy And Physiology, Deborah Hersh, Luzita Fereday, Fiona Palmer, David Hall, Pedro Amarante Andrade, Priscilla Cornelius, Charn Nang, Jane White

Research outputs 2022 to 2026

Objectives: Seeing Voices was an interprofessional, technology-enabled, large-scale, teaching and learning event developed to address the need to improve voice students’ knowledge of laryngeal anatomy and physiology toward understanding and maintaining vocal health. Seeing Voices trialed a novel interprofessional educational approach, collected both quantitative and qualitative data about student experiences of laryngostroboscopic examination, and built a databank of laryngeal recordings for future student learning. Methods: Seeing Voices involved two 3-hour seminars in a large, university lecture space, run by an interprofessional team (speech-language pathologists, vocal coach, Ear Nose and Throat consultant) with quality equipment projecting laryngeal images to large screens …

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The Emerging Role Of Tertiary Lymphoid Structures As Predictive And Prognostic Biomarkers Of Immunotherapy In Cancer, Lidia B. Medhin, Rodas Amanuel, Lydia Warburton, Leslie Calapre, Benhur Amanuel, Elin S. Gray Mar 2026

The Emerging Role Of Tertiary Lymphoid Structures As Predictive And Prognostic Biomarkers Of Immunotherapy In Cancer, Lidia B. Medhin, Rodas Amanuel, Lydia Warburton, Leslie Calapre, Benhur Amanuel, Elin S. Gray

Research outputs 2022 to 2026

Background: Immune checkpoint inhibitors (ICIs) have improved outcomes across several cancers, yet many patients do not respond, highlighting the need for robust predictive biomarkers. Tertiary lymphoid structures (TLS), ectopic lymphoid aggregates that support local antigen presentation and adaptive immune activation, have emerged as potential indicators of favourable prognosis and immunotherapy responsiveness. Methods: This review summarises current clinical and translational evidence examining the prognostic and predictive value of TLS in solid malignancies. Studies assessing TLS presence, organisation, and biological function were identified through searches of major scientific databases and evaluated with respect to their association with patient outcomes and responses to …

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Magnetically Driven Engineering Of Magnetic Hydroxyapatite/Ca Ro Membranes: Enhancing Surface Physicochemical Properties For High-Performance Water Desalination, Fariba Oulad, Ali Akbar Zinatizadeh, Sirus Zinadini, Amir Razmjou, Sara Eavani Mar 2026

Magnetically Driven Engineering Of Magnetic Hydroxyapatite/Ca Ro Membranes: Enhancing Surface Physicochemical Properties For High-Performance Water Desalination, Fariba Oulad, Ali Akbar Zinatizadeh, Sirus Zinadini, Amir Razmjou, Sara Eavani

Research outputs 2022 to 2026

This research focuses on the development of innovative hydrophilic reverse osmosis (RO) hydroxyapatite/cellulose acetate (HAP/CA) and magnetic-hydroxyapatite (M-HAP)/CA membranes, utilizing a phase-inversion technique with varying nanoparticles (NPs) concentration. The positioning of magneto-responsive M-HAP NPs within the advanced M-HAP/CA membranes was adeptly controlled using magnetic guidance during immersion- precipitation process in a coagulation bath. This precise control enabled a densely organized arrangement of M-HAP NPs, shifting from the membrane's core to its upper separation layer. Consequently, the barrier properties, mechanical integrity, and surface characteristics of the advanced M-HAP/CA membranes saw significant enhancement due to the uniform distribution of hydrophilic porous NPs …

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A High-Fidelity Multimodal Synthetic Dataset Generation Framework For Off-Road Unstructured Terrain Navigation Training Of Autonomous Robots, Liyana Wijayathunga, Dulitha Dabare, Alexander Rassau, Douglas Chai, Syed Mohammed Shamsul Islam Mar 2026

A High-Fidelity Multimodal Synthetic Dataset Generation Framework For Off-Road Unstructured Terrain Navigation Training Of Autonomous Robots, Liyana Wijayathunga, Dulitha Dabare, Alexander Rassau, Douglas Chai, Syed Mohammed Shamsul Islam

Research outputs 2022 to 2026

The success of deep learning methods in a wide range of application areas has inspired many recent developments in the urban and off-road autonomous navigation domain. In particular, techniques for semantic scene understanding, a key aspect of the navigation pipeline, have been researched extensively, resulting in many real-world and synthetic datasets. However, in comparison to urban semantic segmentation datasets, the availability of datasets for off-road environments remains sparse. In this paper, we aim to overcome this challenge by introducing a methodology capable of efficiently generating photorealistic synthetic datasets for off-road environments with support for multiple sensor modalities. The developed approach …

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An Explainable Transformer-Based Model For Phishing Email Detection: A Large Language Model Approach, Mohammad Amaz Uddin, Md Mahiuddin, Iqbal H. Sarker Mar 2026

An Explainable Transformer-Based Model For Phishing Email Detection: A Large Language Model Approach, Mohammad Amaz Uddin, Md Mahiuddin, Iqbal H. Sarker

Research outputs 2022 to 2026

Phishing email is a serious cyber threat that tries to deceive users by sending false emails with the intention of stealing confidential information or causing financial harm. Attackers, often posing as trustworthy entities, exploit technological advancements and sophistication to make the detection and prevention of phishing more challenging. Despite extensive academic research, phishing detection remains an ongoing and formidable challenge in the cybersecurity landscape. In this research paper, we present a fine-tuned transformer-based masked language model, RoBERTa (Robustly Optimized BERT Pretraining Approach), for phishing email detection. In the detection process, we employ a phishing email dataset and apply the preprocessing …

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Automated Abdominal Aortic Calcification Scores And Atherosclerotic Cardiovascular Disease In The Uk Biobank Imaging Study, Marc Sim, James Webster, Cassandra Smith, Afsah Saleem, Syed Zulqarnain Gilani, Carlos J. Toro-Huamanchumo, David Suter, Gemma Figtree, Anne Karine Lagendijk, Emma L. Duncan, Carl Schultz, Pawel Szulc, Joseph Hung, Wai H. Lim, Parminder Raina, Nicola P. Bondonno, Richard Woodman, Jonathan M. Hodgson, Douglas P. Kiel, Richard L. Prince, William D. Leslie, John P. Kemp, Nicholas C. Harvey, John T. Schousboe, Joshua R. Lewis Mar 2026

Automated Abdominal Aortic Calcification Scores And Atherosclerotic Cardiovascular Disease In The Uk Biobank Imaging Study, Marc Sim, James Webster, Cassandra Smith, Afsah Saleem, Syed Zulqarnain Gilani, Carlos J. Toro-Huamanchumo, David Suter, Gemma Figtree, Anne Karine Lagendijk, Emma L. Duncan, Carl Schultz, Pawel Szulc, Joseph Hung, Wai H. Lim, Parminder Raina, Nicola P. Bondonno, Richard Woodman, Jonathan M. Hodgson, Douglas P. Kiel, Richard L. Prince, William D. Leslie, John P. Kemp, Nicholas C. Harvey, John T. Schousboe, Joshua R. Lewis

Research outputs 2022 to 2026

Background: Abdominal aortic calcification (AAC) is a subclinical measure of atherosclerotic cardiovascular disease (ASCVD). AAC can be captured on lateral spine images obtained from bone density machines during routine osteoporosis screening. Identifying individuals with AAC provides a new opportunity to prevent disease progression. Objectives: The aim of the study was to externally validate a machine learning-derived AAC 24-point algorithm (ML-AAC24) with incident ASCVD. Methods: Middle-aged individuals from the UK Biobank Imaging Study with lateral spine images, obtained via dual-energy x-ray absorptiometry, were included. ML-AAC24 scores were grouped as low (<2), moderate (2 to <6), and high (≥6). Linked health records were used to identify ASCVD-associated events, including hospitalizations and death. Results: Among 53,611 participants (52% female; mean age 65 years), 78.2% had low, 16.4% had moderate, and 5.4% had high ML-AAC24. After excluding people with prevalent ASCVD or missing data, 1,163 (2.3%) of 50,923 people had an incident ASCVD event over a median follow-up of 4.1 [3.0-5.5] years. In age- and sex-adjusted analysis, compared to those with low ML-AAC24, those with moderate (HR: 1.80 [95% CI: 1.57-2.08]) and high ML-AAC24 (HR: 2.87 [95% CI: 2.39-3.44]) had a higher HR for incident ASCVD. Results remained comparable after adjustment for established ASCVD risk factors. Consistent patterns were observed when considering incident coronary artery disease, myocardial infarction, and stroke. Conclusions: Assessing ML-AAC24 on lateral spine images offers a new and promising screening method to identify people with higher risk of incident ASVD events.

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Hospital-Presenting Self-Harm And Suicide Among Justice-Involved Adolescents On Community-Based Orders: A Population-Based Cohort Study, Emaediong I. Akpanekpo, George Karystianis, Jocelyn Jones, Tony Butler Mar 2026

Hospital-Presenting Self-Harm And Suicide Among Justice-Involved Adolescents On Community-Based Orders: A Population-Based Cohort Study, Emaediong I. Akpanekpo, George Karystianis, Jocelyn Jones, Tony Butler

Research outputs 2022 to 2026

Objective To estimate the incidence and identify risk factors for hospital-presenting self-harm and suicide among justice-involved adolescents serving community-based orders in New South Wales, Australia. Method We conducted a population-based retrospective cohort study of 44,887 adolescents aged 10–17 years at first proven offence who received community-based orders between 1994 and 2020. Hospital and emergency department records were linked with mortality, child protection, and justice data. Cox regression estimated hazard ratios (HRs) for self-harm, and Fine-Gray models estimated subdistribution HRs for suicide, accounting for competing risks. Results Over 163,676 person-years, 1901 adolescents had a first self-harm episode (11.6 per 1000 person-years), …

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Numerical Investigation On Enhancing The Performance Of A Parabolic Trough Collector Using A Threaded Absorber Tube, Shayan Pourhemmati, Abdellah M. Shafieian, Hussein A. Mohammed, Barun Kumar Das, Majid Tolouei-Rad Mar 2026

Numerical Investigation On Enhancing The Performance Of A Parabolic Trough Collector Using A Threaded Absorber Tube, Shayan Pourhemmati, Abdellah M. Shafieian, Hussein A. Mohammed, Barun Kumar Das, Majid Tolouei-Rad

Research outputs 2022 to 2026

The growing global demand for energy and heightened environmental concerns have elevated the importance of solar energy harvesting in recent years. Parabolic trough collectors (PTCs) are widely utilized for capturing direct solar radiation; however, conventional PTC efficiency is limited by low convection heat transfer rate in the absorber section, which is then delivered to heat transfer fluid (HTF). This study numerically investigates the use of a threaded tube as a fluid flow disruption technique to enhance heat transfer rate within the absorber, with Reynolds numbers ranging from 4000 to 10,000. Three key geometric parameters of the thread: pitch (300, 150 …

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Participatory Action Research (Par) In Designing A Supplementary Animated Teaching Resource To Support Learning Cervical Assessment, Michelle Gray, Shelley Stuart, Melanie Welfare Mar 2026

Participatory Action Research (Par) In Designing A Supplementary Animated Teaching Resource To Support Learning Cervical Assessment, Michelle Gray, Shelley Stuart, Melanie Welfare

Research outputs 2022 to 2026

Aim: To create an education resource that assists students to understand the movement of the cervix during labour from a posterior retroverted position to a central location, cervical effacement, dilatation of the cervix and descent of the fetal skull. Background: Learning about anatomy and physiology in relation to cervical effacement and dilatation are abstract concepts that are difficult to understand from reading alone. Diagrams are of little assistance however 3D animation has the potential to improve students learning experiences. Design: Participatory Action Research (PAR) using the 7 C's Feekery Framework approach was adopted. Participants became coresearchers in conceptualising the learning …

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Physical Fitness And Executive Functions In Early Childhood: A Systematic Review Of Recent Evidence, Nemanja Lakicevic, Marko Manojlovic, Elena Chichinina, Apollinaria Chursina, Kristina Tarasova, Ewan Thomas, Yuming Zhong, Antonino Bianco, Patrik Drid Mar 2026

Physical Fitness And Executive Functions In Early Childhood: A Systematic Review Of Recent Evidence, Nemanja Lakicevic, Marko Manojlovic, Elena Chichinina, Apollinaria Chursina, Kristina Tarasova, Ewan Thomas, Yuming Zhong, Antonino Bianco, Patrik Drid

Research outputs 2022 to 2026

Background Optimizing physical fitness (PF) and developing executive functions (EFs) is of great importance in preschool children. The link between PF, obtained through repetitive physical activity, and EFs is gaining increasing attention in recent years and we sought to systematically search the literature on the relationship between PF and EFs in preschool children published in the last five years. Methods Web of Science, Scopus, and PubMed were databases searched for the relevant literature. Original studies written in English and published in peer-reviewed journals including healthy children aged 3–6 years who were simultaneously tested for PF and EFs were considered eligible. …

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Preserving Residual Kidney Function In Haemodialysis: Current Practices, Challenges, And Perspectives From Renal Clinicians, Lijun Zhong, Ulrich Steinwandel, Hugh Davies, Sara Bayes, Jagadish Jamboti, Hemant Kulkarni, Doris Chan Mar 2026

Preserving Residual Kidney Function In Haemodialysis: Current Practices, Challenges, And Perspectives From Renal Clinicians, Lijun Zhong, Ulrich Steinwandel, Hugh Davies, Sara Bayes, Jagadish Jamboti, Hemant Kulkarni, Doris Chan

Research outputs 2022 to 2026

Background: Residual kidney function in patients receiving haemodialysis is associated with improved survival, reduced cardiovascular risk and better quality of life. Yet, clinical guidelines on its preservation are limited, and local practices remain unclear. Objectives: To explore current practices, perceptions and challenges related to residual kidney function preservation among renal clinicians. Design: Descriptive cross-sectional survey. Participants: Renal physicians and nurses working in hospital-based haemodialysis units across Western Australia. Measurements: Role-specific questionnaires were administered to renal physicians and nurses. Results: Eighty-four completed responses were received (physicians n = 25; nurses n = 59). Over half of physicians (56%, n = 14) …

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State Of Charge Estimation Of Ev Secondary Battery Pack Using Hybrid Hedge Feedforward Feedback-Based Gated Recurrent Unit To Extend Lifespan, Md Ohirul Qays, Iftekhar Ahmad, Daryoush Habibi, Mohammad A.S. Masoum, Paul Moses Mar 2026

State Of Charge Estimation Of Ev Secondary Battery Pack Using Hybrid Hedge Feedforward Feedback-Based Gated Recurrent Unit To Extend Lifespan, Md Ohirul Qays, Iftekhar Ahmad, Daryoush Habibi, Mohammad A.S. Masoum, Paul Moses

Research outputs 2022 to 2026

Accurate estimation of state of charge (SoC) and maintaining balanced charge levels across secondary battery cells are crucial in battery management systems (BMSs) to extend battery life while improving the performance and thermal stability of Li-ion batteries (LIBs) in electric vehicles (EVs). However, there are still underexplored challenges associated with circulating currents in electrochemical cells during continuous operation which can overheat battery packs, reducing their life span or result in dangerous thermal runaways. This paper investigates SoC estimation using various real-world charging and discharging profiles, along with charge-balancing strategies to enhance the longevity of parallel-connected Li-ion battery cells. A newly …

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User Experience (Ux) Meets Bureaucracy: Lessons From A Government Intranet Prototype, Scott Pelham, Jo Jung, Christopher Kueh Mar 2026

User Experience (Ux) Meets Bureaucracy: Lessons From A Government Intranet Prototype, Scott Pelham, Jo Jung, Christopher Kueh

Research outputs 2022 to 2026

Implementing user experience (UX) methodologies within government settings is both possible and powerful – but fraught with systemic and cultural complexities. This report presents insights from the redesign of a government intranet for a prominent Australian emergency services organisation, using a human-centred design approach grounded in the Double Diamond framework. The research reveals a series of challenges: bureaucracy, opinion bias, overwhelming content volume with minimal organisational value, a governance paradox where design rules are desired but selectively applied, a disconnect in engagement from key stakeholders, and the impact of a design by committee approach. While these challenges were significant, they …

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Widespread Decline In The Abundance Of Sea Cucumber Assemblages In Atolls Of The Protected Rowley Shoals, Northwestern Australia, Inês Leal, Claire L. Ross, Simone Strydom, Richard D. Evans, Thomas H. Holmes, Graham J. Edgar, John K. Keesing Mar 2026

Widespread Decline In The Abundance Of Sea Cucumber Assemblages In Atolls Of The Protected Rowley Shoals, Northwestern Australia, Inês Leal, Claire L. Ross, Simone Strydom, Richard D. Evans, Thomas H. Holmes, Graham J. Edgar, John K. Keesing

Research outputs 2022 to 2026

The Rowley Shoals, off northwestern Australia, are renowned as a biodiversity hotspot. This remote system comprises three atolls, Clerke, Imperieuse and Mermaid, which in recent years have been increasingly targeted by illegal fishing, a pressure rising across the Indo-Pacific. The objective of this study was to quantify recent changes in sea cucumber assemblages across the Rowley Shoals. We surveyed nine sea cucumber species at monitoring sites in 2018 and 2023 to assess changes in their abundance. Total assemblage densities declined significantly across all atolls and habitats. Documented seizures of illegally harvested holothurians by the Australian Fisheries Management Authority over this …

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A Joint Effort: Stakeholders' Perspectives Of Medication Management Reviews In Australian Residential Aged Care, Rajendra Gyawali, Marea O'Donnell, Rachel Jenkins, Amy D. Nguyen, Lalit Yadav, Rosemary Saunders, Fiona J. Clay, Johanna I. Westbrook, Karla Seaman, Magdalena Z. Raban Mar 2026

A Joint Effort: Stakeholders' Perspectives Of Medication Management Reviews In Australian Residential Aged Care, Rajendra Gyawali, Marea O'Donnell, Rachel Jenkins, Amy D. Nguyen, Lalit Yadav, Rosemary Saunders, Fiona J. Clay, Johanna I. Westbrook, Karla Seaman, Magdalena Z. Raban

Research outputs 2022 to 2026

Objective: Residential Medication Management Review (RMMR) is a government-funded pharmacist-led service to address medication-related problems, such as polypharmacy, which are prevalent in aged care. Despite known benefits, concerns remain about the service's effective implementation to benefit residents. We aimed to explore stakeholders' perspectives of the service and identify challenges and improvement opportunities. Method: A qualitative study was conducted using individual interviews and focus groups with 21 stakeholders, including general practitioners (GPs), a nurse practitioner, registered nurses, pharmacists and consumers. Audio transcripts of the discussions were thematically analysed using inductive coding. Results: Seven interconnected themes were identified, highlighting complexities in RMMR …

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Between Conformity And Change: How Institutional Forces Shape, And Are Shaped By, Projects, Masoud Aghajani, Ashkan Memari, Shankar Sankaran Mar 2026

Between Conformity And Change: How Institutional Forces Shape, And Are Shaped By, Projects, Masoud Aghajani, Ashkan Memari, Shankar Sankaran

Research outputs 2022 to 2026

Projects operate within institutional environments that shape their structures, practices, and legitimacy. At the same time, projects may contribute to institutional stabilization, adaptation, or incremental change. A growing body of research has applied institutional theory to examine these interactions; however, the literature remains dispersed across various contexts and levels of analysis, thereby limiting a cumulative understanding of how institutional and project dynamics are interconnected. This paper undertakes an integrative review of 119 publications that apply organizational institutional theory in project management studies. The findings build upon earlier research to consolidate this body of work and clarify how institutional forces shape …

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Comparing Methods For Measuring 210po In Seawater: Fe(Oh)3 Can Extract Less 210po Than Co-Apdc And Thus Overestimate Poc Export Fluxes, Harold Carrasco, J. Kirk Cochran, Beat Gasser, Inés Sanz-Alvarez, Montserrat Roca-Martí, Christina Heilbrun, Nicholas S. Fisher, Jana Friedrich, Pere Masqué Mar 2026

Comparing Methods For Measuring 210po In Seawater: Fe(Oh)3 Can Extract Less 210po Than Co-Apdc And Thus Overestimate Poc Export Fluxes, Harold Carrasco, J. Kirk Cochran, Beat Gasser, Inés Sanz-Alvarez, Montserrat Roca-Martí, Christina Heilbrun, Nicholas S. Fisher, Jana Friedrich, Pere Masqué

Research outputs 2022 to 2026

Over six decades of research, two methods have been used to extract the natural radionuclides 210Pb and 210Po from seawater- the precipitation of iron hydroxide (Fe(OH)3) and coagulation of cobalt ammonium pyrrolidine dithiocarbamate (Co-APDC). Although the two methods had been intercompared for 210Pb and shown to agree, they were never intercompared for 210Po until Roca-Martí et al. (2021) , in which only unfiltered samples were used. Here we document that Fe(OH)3 may be less effective in extracting 210Po from a seawater sample than Co-APDC. We hypothesize that cycling of 210Po through the marine food …

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Dietary Flavonoid Intake And Psychological Well-Being – A Bidirectional Relationship, Alysha S. Thompson, Nicola P. Bondonno, Yan Lydia Liu, Farah Qureshi, Laura D. Kubzansky, Claudia Trudel-Fitzgerald, Julia K. Boehm, Eric B. Rimm, Aedín Cassidy Mar 2026

Dietary Flavonoid Intake And Psychological Well-Being – A Bidirectional Relationship, Alysha S. Thompson, Nicola P. Bondonno, Yan Lydia Liu, Farah Qureshi, Laura D. Kubzansky, Claudia Trudel-Fitzgerald, Julia K. Boehm, Eric B. Rimm, Aedín Cassidy

Research outputs 2022 to 2026

Background and aim: Higher dietary flavonoid intake has been associated with lower risks of mortality and major chronic disease, yet its relationship with psychological well-being (PWB), a key contributor to health and quality of life, remains unclear. This study aimed to investigate bidirectional associations between dietary flavonoid intake and two PWB facets: happiness (positive emotional state) and optimism (generalized expectation of positive outcomes). Specifically, we examined whether (1) overall flavonoid-rich dietary patterns (flavodiet score), (2) intake of specific flavonoid-rich foods, and (3) total flavonoid and subclass intakes were each associated with happiness and optimism over time. Methods: Data were drawn …

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Evaluation Of Sanafoam Vaporooter Ii Stress On Activated Sludge Performance For Carbonaceous Removal And Nitrification, Ensiyeh Taheri, Ali Fatehizadeh, John Nazimek, Mustafa Nabi, Wayne Bagg, Amir Razmjou, Paul Nolan, Ratish Permala, Mehdi Khiadani Mar 2026

Evaluation Of Sanafoam Vaporooter Ii Stress On Activated Sludge Performance For Carbonaceous Removal And Nitrification, Ensiyeh Taheri, Ali Fatehizadeh, John Nazimek, Mustafa Nabi, Wayne Bagg, Amir Razmjou, Paul Nolan, Ratish Permala, Mehdi Khiadani

Research outputs 2022 to 2026

Root intrusion control in sewer pipelines often relies on chemical herbicides, yet their unintended impacts on downstream biological treatment remain underexplored. This study investigated the effects of Sanafoam Vaporooter II (SVII) on carbon removal and nitrification in activated sludge reactors (ASRs) under long-term operation. Two parallel bench-scale ASRs were installed and operated at Subiaco municipal wastewater treatment plant in Perth, Western Australia: one was exposed to incremental SVII concentrations (1–3000 mg/L), while the other served as an unamended control. Stoichiometric analysis revealed stable organic matter removal across all SVII doses. In contrast, nitrification decreased progressively at concentrations exceeding 128 mg/L. …

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Explainable Artificial Intelligence Models For Detecting Suspicious Bank Transactions, Narasimha Kumar Narasapuram, Syed Afaq Ali Shah, Mohd Fairuz Shiratuddin, Ferdous Sohel Mar 2026

Explainable Artificial Intelligence Models For Detecting Suspicious Bank Transactions, Narasimha Kumar Narasapuram, Syed Afaq Ali Shah, Mohd Fairuz Shiratuddin, Ferdous Sohel

Research outputs 2022 to 2026

Detecting financial crime is a complex challenge due to evolving criminal strategies and fragmented detection systems, particularly in the areas of money laundering and fraud. While it is easy to implement, traditional rule-based approaches lack adaptability to new threats, and machine learning models, though more effective, often function as opaque "black boxes," limiting their practical use in regulated domains like banking, where interpretability and accountability are essential. This research presents a novel framework that combines intrinsic and post-hoc XAI techniques to detect suspicious bank transactions. Intrinsic methods provide model-inherent transparency, while post-hoc methods offer behavior-level explanations, enabling robust cross-verification of …

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Green And Charge-Tuned Β-Cyclodextrin Polymers For Efficient Removal Of Pfas And Anionic Dyes From Water, Samira Sadeghi, Ahmad Najafidoust, Mark Mullett, Shayan Karimi, Masoumeh Zargar Mar 2026

Green And Charge-Tuned Β-Cyclodextrin Polymers For Efficient Removal Of Pfas And Anionic Dyes From Water, Samira Sadeghi, Ahmad Najafidoust, Mark Mullett, Shayan Karimi, Masoumeh Zargar

Research outputs 2022 to 2026

Water contamination by per- and polyfluoroalkyl substances (PFAS) poses a major environmental challenge due to their persistence. This study evaluates positively charged, green-synthesized β-cyclodextrin polymers (β-CDP+) for the removal of perfluorobutanoic acid (PFBA) and perfluorooctanoic acid (PFOA) as short- and long-chain PFAS, respectively, from water. Methyl orange (MO) and acid red 1 (AR1), as anionic dyes, were used as proxies to optimize PFAS adsorption conditions. β-CDP+ exhibited high removal efficiencies (>90%) for all pollutants within 15–50 mg/L, reaching equilibrium within 30 min. Maximum adsorption capacities (Qm) were achieved for MO (335 mg/g), AR1 (384 mg/g), PFOA …

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Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire Mar 2026

Mass Cytometry Workflow To Achieve High-Dimensional Immunophenotyping In Resource-Limited Or Decentralized Environments, Natalie Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen Mcguire

Research outputs 2022 to 2026

Globally, regional and remote communities are burdened by both an increased prevalence and worse prognosis of many infectious and chronic diseases. However, largely owing to logistical challenges, these communities are under-represented in clinical trials and research studies. As individuals from rural communities experience unique environmental exposures and risk factors for disease, immune phenotyping data collected from metropolitan populations may not be broadly generalizable. To address this, we present a workflow that enables the inclusion of resource-limited sites in high-parameter mass cytometry studies. In this approach, whole blood (WB) or peripheral blood mononuclear cells (PBMCs) are collected, stained fresh for surface …

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Neutrophil Gelatinase-Associated Lipocalin And Neutrophil-To-Lymphocyte Ratio As Indicators Of Nephropathy In Type 2 Diabetic Mellitus Patients In Ghana: A Case-Control Study, Allwell Adofo Ayirebi, Wina Ivy Ofori Boadu, Stephen Twumasi, Samuel Kwarteng, Benedict Sackey, Lilian Antwi Boateng, Joseph Boachie, Samuel Essien-Baidoo, Daniel Nii Martey Antonio, John Agyemang Sah, Afua Marfowaa, Mayfair Adwapa Mpiani, Joachim Baba Domosie, Abiba Khalifah, Emmanuel Ekow Korsah, Ebenezer Senu, Eugene Arele Ansah, Joseph Yorke, Enoch Odame Anto Mar 2026

Neutrophil Gelatinase-Associated Lipocalin And Neutrophil-To-Lymphocyte Ratio As Indicators Of Nephropathy In Type 2 Diabetic Mellitus Patients In Ghana: A Case-Control Study, Allwell Adofo Ayirebi, Wina Ivy Ofori Boadu, Stephen Twumasi, Samuel Kwarteng, Benedict Sackey, Lilian Antwi Boateng, Joseph Boachie, Samuel Essien-Baidoo, Daniel Nii Martey Antonio, John Agyemang Sah, Afua Marfowaa, Mayfair Adwapa Mpiani, Joachim Baba Domosie, Abiba Khalifah, Emmanuel Ekow Korsah, Ebenezer Senu, Eugene Arele Ansah, Joseph Yorke, Enoch Odame Anto

Research outputs 2022 to 2026

Introduction: Serum neutrophil gelatinase-associated lipocalin (sNGAL), a renal tubular marker, and neutrophil-to-lymphocyte ratio (NLR), a hematological inflammatory marker are two biomarkers that have recently received attention, because of their association with kidney disease. This study examined the diagnostic value sNGAL and NLR in type 2 diabetes mellitus (T2DM) patients with nephropathy. Materials and Methods: In this hospital-based case-control research, 97 T2DM participants and 70 healthy subjects were included. Participants' information was documented using a structured questionnaire and patient case records. Venous blood was drawn from each participant and early morning midstream urine samples were collected for blood and urine measurements …

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Optimizing Agility Training In Team Sport Players—The Role Of Perception-Action Coupling: A Systematic Review With Multi-Level Meta-Analysis, Zhiwei Zhao, Yuhang Liu, Kai Xu Mar 2026

Optimizing Agility Training In Team Sport Players—The Role Of Perception-Action Coupling: A Systematic Review With Multi-Level Meta-Analysis, Zhiwei Zhao, Yuhang Liu, Kai Xu

Research outputs 2022 to 2026

Agility, characterized by rapid whole-body movement in response to external stimuli, is a key performance determinant in team sports owing to its reliance on perception-action coupling. Despite its importance, existing evidence on training effects is disproportionately focused on change-of-direction ability, overlooking the perceptual-cognitive demands of true agility. This systematic review therefore sought to quantify the effects of agility-specific training, examine moderators and establish dose-response model in team-sport players, while accounting for perception-action coupling. Following PRISMA 2020 guidelines, systematic searches were conducted in Web of Science, Scopus and PubMed for peer-reviewed English-language studies. Risk of bias was appraised using a modified …

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Pleural Metastases From Acral Lentiginous Melanoma Diagnosed By Medical Thoracoscopy, Ad Rian Chong, Khai Lip Ng, Nai-Chien Huan, Nur Husna Mohd Aminudin, Fazilah Hassan, Kasuma Mohamed Nordin Mar 2026

Pleural Metastases From Acral Lentiginous Melanoma Diagnosed By Medical Thoracoscopy, Ad Rian Chong, Khai Lip Ng, Nai-Chien Huan, Nur Husna Mohd Aminudin, Fazilah Hassan, Kasuma Mohamed Nordin

Research outputs 2022 to 2026

Acral lentiginous melanoma (ALM) with pleural metastases is rare and under-recognised. We report an 86-year-old woman with progressive dyspnoea and pleuritic chest pain. 18 months ago, she was diagnosed with stage IIC ALM of the right heel, and was treated with wide local excision, but she declined adjuvant therapy. Imaging demonstrated a large left pleural effusion with diffuse pleural thickening, pulmonary mass, and hepatic metastases. Brownish pleural fluid, along with thoracoscopic identification of multiple pigmented nodules, led to a histologically confirmed diagnosis. Talc pleurodesis was performed for symptom control, and best supportive care was pursued. This case highlights the diagnostic …

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Reimagining Peer-Led Support In Doctoral Nursing And Midwifery Education: A Collaborative Autoethnographic Case Study, Gideon U. Johnson, Sachini Thennakoon, Mayumi Kumarage, Emy Toutountzis, Lisa Whitehead Mar 2026

Reimagining Peer-Led Support In Doctoral Nursing And Midwifery Education: A Collaborative Autoethnographic Case Study, Gideon U. Johnson, Sachini Thennakoon, Mayumi Kumarage, Emy Toutountzis, Lisa Whitehead

Research outputs 2022 to 2026

Aim: To explore how peer-led initiatives can enhance connection, belonging and sustainability within higher degree by research (HDR) nursing and midwifery programmes. Background: HDR study can be an isolating experience, often characterised by fragmented support and limited opportunities for structured peer learning. While institutions provide formal mechanisms for supervision and progress, less attention has been given to student-led approaches that cultivate inclusive scholarly communities and sustained peer engagement. Design: Collaborative autoethnographic case study. Methods: HDR student representatives and academic staff at Edith Cowan University, Australia (2022–2024), reflected collaboratively on the design, implementation and impact of peer-led initiatives, including monthly hybrid …

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Synergist Free Solvent Extraction Of Lithium From Alkaline Salt Lake Brines Using Thenoyltrifluoroacetone In Octanol, Shayan Abrishami, Amir Razmjou Mar 2026

Synergist Free Solvent Extraction Of Lithium From Alkaline Salt Lake Brines Using Thenoyltrifluoroacetone In Octanol, Shayan Abrishami, Amir Razmjou

Research outputs 2022 to 2026

The growing demand for lithium in energy storage applications necessitates the development of efficient and selective extraction technologies for recovering lithium from alkaline brines containing high concentrations of competing alkali metals. This study presents an investigation of a thenoyltrifluoroacetone (TTA)-octanol solvent extraction system for selective lithium recovery from high‑sodium brines, utilizing 1-octanol as an environmentally benign diluent without requiring any synergistic co-extractant. Through systematic optimization of key operational parameters including pH, extractant concentration, scrubbing conditions, and stripping agent concentration, the system demonstrated excellent performance with lithium extraction efficiency of 67.5% ± 3.4% and a maximum separation factor of 28.0 ± …

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Vibostolimab Coformulated With Pembrolizumab Versus Pembrolizumab Alone As Adjuvant Therapy For High-Risk Stage Iib–Iv Melanoma (Keyvibe-010): A Randomised, Double-Blind, Phase 3 Study, Reinhard Dummer, Jun Guo, Jason J. Luke, Matteo S. Carlino, Dirk Schadendorf, Muhammad A. Khattak, Axel Hauschild, Paolo A. Ascierto, Yu Chen, Sang Joon Shin, Piotr Rutkowski, Zhiguo Luo, Jing Chen, Gareth Rivalland, Corlia Coetzee, Antoni Ribas, Karmele Mujika, Gal Markel, Rodrigo U. Villarroel, Omer Dizdar, Christian Caglevic, Dmitri Grebennik, Kevin Donovan, Clemens Krepler, Georgina V. Long Mar 2026

Vibostolimab Coformulated With Pembrolizumab Versus Pembrolizumab Alone As Adjuvant Therapy For High-Risk Stage Iib–Iv Melanoma (Keyvibe-010): A Randomised, Double-Blind, Phase 3 Study, Reinhard Dummer, Jun Guo, Jason J. Luke, Matteo S. Carlino, Dirk Schadendorf, Muhammad A. Khattak, Axel Hauschild, Paolo A. Ascierto, Yu Chen, Sang Joon Shin, Piotr Rutkowski, Zhiguo Luo, Jing Chen, Gareth Rivalland, Corlia Coetzee, Antoni Ribas, Karmele Mujika, Gal Markel, Rodrigo U. Villarroel, Omer Dizdar, Christian Caglevic, Dmitri Grebennik, Kevin Donovan, Clemens Krepler, Georgina V. Long

Research outputs 2022 to 2026

Background Combination therapy with vibostolimab plus pembrolizumab has previously shown promising antitumor activity in melanoma. We aimed to evaluate the efficacy and safety of vibostolimab coformulated with pembrolizumab as adjuvant therapy for high-risk resected melanoma. Methods This randomised, double-blind, phase 3 study was done at 205 global sites (hospitals and cancer centres). Participants aged 12 years or older with surgically resected, stage IIB–IV cutaneous melanoma per the American Joint Committee on Cancer Cancer Staging Manual 2017 (8th edition), with no evidence of metastatic disease after resection, were randomly assigned (1:1) to receive vibostolimab 200 mg coformulated with pembrolizumab 200 mg …

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Work Challenges And Cancer-Related Cognitive Impairment: Level Of Education Accounts For Unmet Needs Beyond Cognitive Impairment Severity, Darren Haywood, Susan L. Rossell, Ashley Henneghan, Frank D. Baughman, Jennifer Haywood, Evan Dauer, Annika Hegde, Ahmed A. Moustafa, Nicolas H. Hart Mar 2026

Work Challenges And Cancer-Related Cognitive Impairment: Level Of Education Accounts For Unmet Needs Beyond Cognitive Impairment Severity, Darren Haywood, Susan L. Rossell, Ashley Henneghan, Frank D. Baughman, Jennifer Haywood, Evan Dauer, Annika Hegde, Ahmed A. Moustafa, Nicolas H. Hart

Research outputs 2022 to 2026

Purpose: Cancer-related cognitive impairment (CRCI) can impact cancer survivors’ return to work and occupational functioning for many years following the completion of cancer treatment. Understanding the characteristics of CRCI-related occupational difficulties and unmet supportive care needs is critical for the development of effective interventions. Within occupational roles, a higher level of education is typically associated with greater cognitive load and different demands. The objective of this study was to examine whether the level of education accounted for CRCI-related (a) occupational difficulties and (b) occupational unmet supportive care needs, beyond the contributions of perceived cognitive functioning and employment level. Methods: A …

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