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Review Of Belle Da Costa Greene: A Librarian's Legacy, Raegan Stearns Mar 2026

Review Of Belle Da Costa Greene: A Librarian's Legacy, Raegan Stearns

LWLC Faculty Research

Belle da Costa Greene: A Librarian’s Legacy is a 303-page catalog for the Morgan Library and Museum’s exhibition of the same name, which ran from October 25, 2024, through May 4, 2025. Both the catalog and exhibition explore the life and professional contributions of Belle da Costa Greene (1879–1950), the museum’s first director upon its establishment as a public institution in 1924.


Ifnγ-Induced Antigen Loss In Chimeric Antigen Receptor-T Cell Therapy, Miao Cao, Jasmine Alvarez, Ramkrishna Mitra, Michael Xu, Trevor R. Baybutt, Zhengyang Sun, Oluwatobiloba Taylor, Allison Doermann, Ross E Staudt, Scott A. Waldman, Adam E. Snook Mar 2026

Ifnγ-Induced Antigen Loss In Chimeric Antigen Receptor-T Cell Therapy, Miao Cao, Jasmine Alvarez, Ramkrishna Mitra, Michael Xu, Trevor R. Baybutt, Zhengyang Sun, Oluwatobiloba Taylor, Allison Doermann, Ross E Staudt, Scott A. Waldman, Adam E. Snook

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

INTRODUCTION: FDA-approved chimeric antigen receptor (CAR)-expressing T cell therapies (CARTs) have revolutionized the treatment of blood cancers. Yet none have been successful for "solid" tumors, such as colorectal cancer (CRC), the 2nd leading cause of cancer deaths. Guanylyl cyclase C (GUCY2C) has emerged as a clinical-stage target for CART and bispecific T-cell engager (BiTE) therapies in CRC. IFNγ has been canonically recognized as beneficial for the effector functions of T cells by enhancing antigen processing and HLA presentation and is essential for CART targeting of solid malignancies by inducing adhesion molecule expression for synapse stabilization.

METHODS: Using

RESULTS: We identified …


Impact Of Urban Roadway Work Zones On Road Users And Other Stakeholders, Lyndsey Renee Harris Mar 2026

Impact Of Urban Roadway Work Zones On Road Users And Other Stakeholders, Lyndsey Renee Harris

Lyles School of Civil Engineering Graduate Student Reports

As urban populations continue to rise at an unprecedented rate, the need for highly maintained infrastructure in cities -- buildings, utilities, and transportation networks -- has become increasingly critical. An urban work zone refers to a designated area within a city where roadway construction, maintenance, or rehabilitation activities are taking place. These zones are typically characterized by high traffic volumes, complex roadway networks, and proximity to residential, institutional, and commercial land uses. Urban work zones often involve lane closures, detours, reduced speed limits, and temporary traffic control measures to ensure safety for road workers and road users. Due to the …


Holographic Photopolymerizable Glass: Enhancing Exposure Sensitivity By Tailoring Photoinitiating Systems Based On Bodipy Dyes, Tatsiana Mikulchyk, Aimee Sheehan, Metodej Dvoracek, Izabela Naydenova, Mikhail Filatov Mar 2026

Holographic Photopolymerizable Glass: Enhancing Exposure Sensitivity By Tailoring Photoinitiating Systems Based On Bodipy Dyes, Tatsiana Mikulchyk, Aimee Sheehan, Metodej Dvoracek, Izabela Naydenova, Mikhail Filatov

Research Outputs: 2025-Present

The photoinitiating system (PIS) is a key component of holographic materials which needs to be carefully selected and optimized to achieve efficient photopolymerization and, as a result, highly efficient holographic structures. Recently, boron dipyrromethene (BODIPY) dyes have been introduced as a new class of photosensitizers for holographic materials, including photopolymerizable glass, which is characterized by excellent environmental stability. Here, we present a study of the holographic recording capability of the photopolymerizable glass, where PIS was optimized using two approaches: 1) adding a second co-initiator, diphenyl iodonium hexafluorophosphate (DPIHFP) and 2) exploring a range of BODIPY structures, such as anthracene- and …


Vision-Language System Using Open-Source Llms For Consent And Instruction Gestures In Medical Interpreter Robots, Thanh Tung Ngo, Emma Murphy, Robert J. Ross Mar 2026

Vision-Language System Using Open-Source Llms For Consent And Instruction Gestures In Medical Interpreter Robots, Thanh Tung Ngo, Emma Murphy, Robert J. Ross

Research Outputs: 2025-Present

Effective communication is vital in healthcare, especially across language barriers, where non-verbal cues and gestures are critical. This paper presents a privacy-preserving vision-language framework for medical interpreter robots that detects specific speech acts (consent and instruction) and generates corresponding robotic gestures. Built on locally deployed open-source models, the system utilizes a Large Language Model (LLM) with few-shot prompting for intent detection. We also introduce a novel dataset of clinical conversations annotated for speech acts and paired with gesture clips. Our identification module achieved 0.90 accuracy, 0.93 weighted precision, and a 0.91 weighted F1-Score. Our approach significantly improves computational efficiency and, …


Involving Interpol: Interpol’S Meddling In International Parental Kidnapping And International Custody Dispute Cases Through Red And Yellow Notices, Chandler Gallucci Mar 2026

Involving Interpol: Interpol’S Meddling In International Parental Kidnapping And International Custody Dispute Cases Through Red And Yellow Notices, Chandler Gallucci

Child and Family Law Journal

As the world grows more interconnected through globalization, the opportunity for international parental kidnapping has increased. International parental kidnapping occurs when a parent or guardian wrongfully removes and retains a child from their habitual residency, even with the existence of a custody agreement. This article examines the role of the International Criminal Police Organization (“Interpol”) and how their use of Red and Yellow Notices can meddle in international custody disputes. Interpol consists of 196 member states, each of which is connected through Interpol’s database. Interpol links local law enforcement agencies in each of the member states. A Red Notice is …


Gender Ideology Curriculum In Florida Schools: Parental Rights And Educator Strain, Kimberly Mack Mar 2026

Gender Ideology Curriculum In Florida Schools: Parental Rights And Educator Strain, Kimberly Mack

Child and Family Law Journal

No abstract provided.


The Irrelevance Of Filing Speed: Evidence From A Regulatory Reporting Discontinuity, Bryson Mumford Mar 2026

The Irrelevance Of Filing Speed: Evidence From A Regulatory Reporting Discontinuity, Bryson Mumford

Undergraduate Honors Theses

Does faster financial reporting increase firm value? I exploit the $700 million public float threshold in SEC Rule 12b-2, which imposes a 60-day Form 10-K filing deadline for large accelerated filers relative to 75 days for accelerated filers. Using a fuzzy regression discontinuity design, I show that crossing the threshold sharply increases the likelihood of Large Accelerated Filer status and reduces filing lags by approximately one week, with no evidence of concurrent changes in mandated audit quality. Despite this exogenous acceleration in information disclosure, I fail to reject the null hypothesis that there are no effects on firm valuation (Tobin’s …


Beyond The Flames: A Comparative Analysis Of Wildfire Preparedness And Relief In California, Ej Smith Mar 2026

Beyond The Flames: A Comparative Analysis Of Wildfire Preparedness And Relief In California, Ej Smith

Undergraduate Honors Theses

Wildfires in California have devastated homes and communities, with the 2024–2025 Los Angeles fires ranking among the deadliest in state history, killing 31 people and burning more than 37,000 acres across densely populated neighborhoods. In response to these fires, fire services, municipal governments, and nongovernmental organizations coordinated immediate relief efforts across multiple jurisdictions. This research uses a multiple-case study approach to examine the Eaton, Palisades, Line, and Bridge fires to identify practices that supported life safety and response effectiveness, as well as challenges that constrained response operations. Findings indicate that when environmental conditions exceeded suppression capacity, response outcomes within responder …


Innovating For Access: Ai-Enhanced Triage & Intake For Legal Services Organizations, Heidi Behnke Mar 2026

Innovating For Access: Ai-Enhanced Triage & Intake For Legal Services Organizations, Heidi Behnke

Duke Center on Law & Technology

Artificial intelligence (AI) offers opportunities to meaningfully narrow the access to justice gap by improving the ability of Legal Services Organizations (LSOs) to connect individuals with pro se resources and more effectively connect with individuals who could not otherwise advocate for themselves. Some LSO early adopters have already developed or are in the process of developing such tools. Others are unsure where or how to start.

The results of semi-structured interviews of LSO staff, technology vendors, and leaders/experts in fall 2025 provide information that may assist LSOs in responsibly integrating AI-tools into their triage and intake systems. This paper includes …


Strategic Parallels: How Historic Military Tactics Inform Modern Business Strategy, Eli S. Nelson Mar 2026

Strategic Parallels: How Historic Military Tactics Inform Modern Business Strategy, Eli S. Nelson

Undergraduate Honors Theses

The field of business strategy emerged out of military strategy during the mid- twentieth century. Despite this shared DNA, the connection between the two fields has been limited to broad conceptual comparisons and abstract motivational framing. No prior research has paired a specific military history case with a specific modern business case to analyze the parallels between these disciplines in detail.

This research addresses that gap by comparing the German Blitzkrieg campaign during the 1940 invasion of France and the transformation of Ryanair in the early 1990s. Despite being separated by fifty years and operating in completely different domains, the …


Improved Efficiencies With Virtual Wound Nurse Consults: An Evidence-Based Practice, Quality Improvement Project, Brooke M. Mock Contreras Mar 2026

Improved Efficiencies With Virtual Wound Nurse Consults: An Evidence-Based Practice, Quality Improvement Project, Brooke M. Mock Contreras

Graduate Theses, Dissertations, and Capstones

Abstract

Background: Completing wound care consultations using digital technology is an uncommon practice in the acute care setting. Evidence suggests that virtual wound care consultations may decrease consultation completion times and improve departmental efficiency; however, evidence specific to the acute care setting remains limited.

Purpose: The purpose of this evidence-based practice, quality improvement project was to evaluate the feasibility and impact of implementing virtual wound care consultation in the acute care setting to improve departmental efficiency. Efficiency was measured by calculating the total time elapsed between the consultation order and consultation completion.

Methods: Guided by the Model for Improvement and …


Examining Undergraduate Nursing Faculty’S Job Satisfaction Related To Workload, Work-Life Balance, And Student Incivility, Melissa Walch Mar 2026

Examining Undergraduate Nursing Faculty’S Job Satisfaction Related To Workload, Work-Life Balance, And Student Incivility, Melissa Walch

Walden Dissertations and Doctoral Studies

Exploring nursing faculty job satisfaction is important for retaining faculty in undergraduate nursing programs because they are vital to training future bedside nurses. There is a nursing faculty shortage in the United States, and retaining faculty is critical to addressing it. The purpose of this study, guided by Herzberg’s motivation-hygiene theory, was to (a) understand the relationship between workload, work-life balance, and nursing faculty job satisfaction and (b) the relationship between student incivility and nursing faculty job satisfaction in undergraduate nursing programs. Undergraduate nursing faculty in Ohio and Florida with at least 2 years of teaching experience were recruited via …


Obesity And Suicide Behavior In Young Latina Adults Of Mexican Heritage: The Mediating Influences Of Sleep Problems, Health Problems, And Dissatisfaction With Personal Appearance, Joseph D. Hovey, Liza Talavera-Garza, Glenn Gray, Isabella A. Cruz, Nadeen Salhadar, Monica E. Ochoa Mar 2026

Obesity And Suicide Behavior In Young Latina Adults Of Mexican Heritage: The Mediating Influences Of Sleep Problems, Health Problems, And Dissatisfaction With Personal Appearance, Joseph D. Hovey, Liza Talavera-Garza, Glenn Gray, Isabella A. Cruz, Nadeen Salhadar, Monica E. Ochoa

Psychological Science Faculty Publications

Although research findings have indicated that obesity is associated with suicide behavior, especially in females, scant research has examined mediators in this relationship. Moreover, although suicides have increased in young Latina adults in the United States, no published studies have examined obesity and suicide risk in young Latina adults. The present study thus examined the relationship of obesity to suicide behavior in young Latina adults and assessed sleep problems, health problems, and dissatisfaction with personal appearance as possible mediators. Participants were 401 female students of Mexican heritage from South Texas who completed the National College Health Assessment II, from which …


Ephemerality As Stigma In Algorithmic Contexts: Moderation And User-Driven Deletion Of Nonsuicidal Self-Injury Content On Tiktok, Valerie Vera Lookingbill, Ehsan Mohammadi Ph.D. Mar 2026

Ephemerality As Stigma In Algorithmic Contexts: Moderation And User-Driven Deletion Of Nonsuicidal Self-Injury Content On Tiktok, Valerie Vera Lookingbill, Ehsan Mohammadi Ph.D.

Faculty Publications

Social media increasingly serves as important spaces for mental health information seeking and peer support, especially for individuals facing barriers to traditional care. Although nonsuicidal self-injury is frequently discussed on social media, there is limited understanding of the factors that influence the visibility of this discourse. We analyzed 973 videos related to nonsuicidal self-injury on TikTok to examine the prevalence and characteristics of posts that become unavailable (i.e., ephemeral) over time, whether due to user deletion or platform removal. Videos that used addiction-related language, included trigger warnings, or depicted scars were significantly associated with ephemerality. These findings highlight how anticipated …


Masthead & Table Of Contents, Vol. 104, No. 3 Mar 2026

Masthead & Table Of Contents, Vol. 104, No. 3

Nebraska Law Review

No abstract provided.


Sticky Science In Court, H. A. Spitzer Mar 2026

Sticky Science In Court, H. A. Spitzer

Nebraska Law Review

Litigation routinely employs scientific evidence to aid judicial fact-finding and decision-making. This is especially important in areas like family law, where legal standards—such as the best interests of the child—often depend in part on scientific findings. Yet the legal system’s gatekeeping doctrines (Frye, Daubert, and Federal Rule of Evidence 702) apply primarily to expert testimony, leaving other pathways through which scientific evidence reaches courts largely unchecked. These other pathways include citations in briefs and opinions to non-peer-reviewed or non-scientific sources such as law reviews, treatises, and self-published materials, which often become outdated and are not well positioned …


Wcu Digital Commons Accessibility Implementation Plan, Julia Doelling Mar 2026

Wcu Digital Commons Accessibility Implementation Plan, Julia Doelling

Policy Library

No abstract provided.


20260316: College Of Education, 1923-1990, College Of Education And Professional Development Mar 2026

20260316: College Of Education, 1923-1990, College Of Education And Professional Development

Guides to University Archives

These items include materials from the College of Education and Professional Development at Marshall University from 1923-1990. Items were received in the 1990s and were processed in 2026 and include notable information from the College of Ed. Items include a Curriculum Analysis Report for various departments on campus; correspondence from various deans and faculty on campus; the Autism Center in 1984; National Council for Accreditation of Teacher Education reports from the 1970s; and information on The Schools of Fayette County, WV. Please download the finding aid for more information.


Multi-Agent Llm For Reducing Unsheltered Homelessness, Shravya Kothapalli, Samhita Juloori, Vishvaas Vasudeva Rao, Joshna Medisetty, Ahmed Hambaba Mar 2026

Multi-Agent Llm For Reducing Unsheltered Homelessness, Shravya Kothapalli, Samhita Juloori, Vishvaas Vasudeva Rao, Joshna Medisetty, Ahmed Hambaba

Faculty Research, Scholarly, and Creative Activity

This project examines how data science and intelligent systems can enhance homelessness prevention efforts by facilitating early identification and optimized service delivery. Using a synthesized dataset reflective of Santa Clara County populations, we developed predictive models to assess risk factors associated with homelessness, such as rent burden, employment instability, eviction notices, and chronic health conditions. These models inform a multi-agent system recommending targeted interventions across medical, food, and job resources. Our system is designed to prioritize individuals most at risk and match them with appropriate services based on availability, proximity, and personal needs. By integrating geographic data and real-time service …


The Dual-Specificity Phosphatase Jsp1 Regulates Neutrophil Adhesion Via Integrin-Src Signaling In Vascular Inflammation, Li Li Mar 2026

The Dual-Specificity Phosphatase Jsp1 Regulates Neutrophil Adhesion Via Integrin-Src Signaling In Vascular Inflammation, Li Li

BCES: Faculty Publications

The c-JUN N-terminal kinase (JNK) signaling pathway plays an important role in regulating the innate immune response. Immune signaling is governed by the coordinated activity of protein kinases counter-balanced by protein phosphatases; however, the importance of the latter family of enzymes is less well understood. c-JUN N-terminal kinase (JNK)-stimulatory phosphatase 1 (JSP1, also known as DUSP22) has been implicated as a positive regulator of JNK signaling, yet its role in innate immunity is not clear. Using a mouse model of the local Shwartzman reaction, we show that JSP1 is essential for LPS-TNF-alpha-induced vascular injury. JSP1-knockout mice exhibited reduced vascular hemorrhage. …


Aelj Panel: Balancing Free Speech And National Security In The Digital Age, Cardozo Arts & Entertainment Law Journal (Aelj) Mar 2026

Aelj Panel: Balancing Free Speech And National Security In The Digital Age, Cardozo Arts & Entertainment Law Journal (Aelj)

2025–2026 Flyers

No abstract provided.


Metadata For Storytelling: Exploring The Collections As Data Model, Emily Baldoni, Angela Yon, Maddi Loiselle Mar 2026

Metadata For Storytelling: Exploring The Collections As Data Model, Emily Baldoni, Angela Yon, Maddi Loiselle

Faculty and Staff Publications – Milner Library

This article describes a case study in which a small metadata team at Illinois State University Milner Library produced a digital humanities project supporting Collections as Data (CAD) and linked data principles. Despite initial sparse descriptive content, the team recognized great potential for experimentation in a significant World War I archival collection to highlight lesser-known stories, including those of the Pioneer Infantry, women, and noncombatants. Discussion focuses on the strategic approaches in creating granular but scalable metadata for the large digital collection, and application of the data with various tools such as ArcGIS and Wikidata to construct interactive data visualizations, …


Ndls Communicator: Week Of 03.16.26, Notre Dame Law School Mar 2026

Ndls Communicator: Week Of 03.16.26, Notre Dame Law School

NDLS Communicator

The Latest News

  • U.S. Supreme Court Justice Clarence Thomas Reflects on Law, Faith, and Judicial Responsibility at Notre Dame Law School
  • Notre Dame Law School Delegation Visits Insper in São Paulo, Brazil for Joint Faculty Workshop and Scholarly Exchange
  • Notre Dame Law School continues exchange partnership with Ukrainian Catholic University

Alumni News

  • Kyle Sommer '09 J.D.

Student News

  • J.S.D. candidate Perla Khattar

Faculty Briefs

  • Ashley Sanchez
  • Derek Muller
  • Emily Bremer
  • Paul Miller
  • Brett Cavanaugh
  • Paolo Carozza
  • Jimmy Gurulé
  • Mary Ellen O'Connell
  • A.J. Bellia
  • Patrick Corrigan
  • Daniel Slate & Paolo Carozza
  • Vincent Phillip Muñoz
  • Lloyd Mayer

ND Law in the News …


The Prospects Of Car T-Cell Therapies In Changing The Therapeutic Algorithm Of Neurologic Autoimmunities, Marinos C. Dalakas Mar 2026

The Prospects Of Car T-Cell Therapies In Changing The Therapeutic Algorithm Of Neurologic Autoimmunities, Marinos C. Dalakas

Department of Neurosurgery Faculty Papers

T cells, genetically modified to express chimeric antigen receptors (CAR T), successfully used in hemato-oncologic malignancies, are showing promising and sustained benefits in refractory autoimmune neurological diseases, including Myasthenia Gravis, stiff-person syndrome, neuromyelitis optica, myositis, autoimmune neuropathies, and multiple sclerosis. Several reported patients with a steadily progressive disease and evolving disability unresponsive to available therapies, including rituximab and new biologics, after 2-3 months of treatment with CARs targeting CD19-positive, antibody-secreting, long-lived plasma cells, and plasmablasts exhibit impressive, long-lasting, and drug-free clinical improvements with the potential for immune reset shifting immunity to a healthy state without the need for continuing more …


Seeds Of Change - Building Community And Resilience With Plant Guilds, Roslynn Mccann, Liliane Dionne, Kevin White Mar 2026

Seeds Of Change - Building Community And Resilience With Plant Guilds, Roslynn Mccann, Liliane Dionne, Kevin White

All Current Publications

The goals of this Grade 6 living systems/biodiversity curriculum are to highlight Indigenous (First Nations, Métis, and Inuit) contributions to science, technology, and sustainable agriculture, with a focus on relational worldviews, permaculture practices, and respect for Mother Earth. Students will conduct plant experiments, learn Indigenous stories, make corn husk dolls, create a recipe, and enjoy eating their soup creation.


Ai Dependency Vs. Doctoral Identity: How Generative Ai Is Challenging The Development Of Independent Scholarly Thinking In Doctoral Students, Valerie A. Storey Mar 2026

Ai Dependency Vs. Doctoral Identity: How Generative Ai Is Challenging The Development Of Independent Scholarly Thinking In Doctoral Students, Valerie A. Storey

All Faculty and Staff Scholarship

The rise of Generative Artificial Intelligence (GenAI) in higher education has altered the conditions under which doctoral students learn, research, and develop as scholars. Although doctoral student use of GenAI has accelerated rapidly, institutional frameworks for responsible and developmentally appropriate use have not kept pace. This paper examines a central paradox in doctoral education: the same tools that enhance research productivity may also weaken intellectual independence when used without guidance. Using a critical review methodology, the study synthesizes 47 sources on doctoral education, GenAI use, policy, and epistemic development. Three interconnected dimensions of risk emerged from the analysis: critical thinking …


Clinical Practice Guideline By The Infectious Diseases Society Of America And The Pediatric Infectious Diseases Society: 2026 Guideline Update On The Management Of Community-Acquired Pneumonia In Infants And Children Older Than 3 Months Of Age, Shawn D St Peter, Krow Ampofo, Thomas Brogan, Michael D Cabana, Claudia Espinosa, Todd A Florin, Jeffrey S Gerber, Michelle Gill, Debra L Palazzi, Mark Sawyer, Angela M Statile, Derek J Williams, Sheena Patel, Mark I Neuman, Samir S Shah Mar 2026

Clinical Practice Guideline By The Infectious Diseases Society Of America And The Pediatric Infectious Diseases Society: 2026 Guideline Update On The Management Of Community-Acquired Pneumonia In Infants And Children Older Than 3 Months Of Age, Shawn D St Peter, Krow Ampofo, Thomas Brogan, Michael D Cabana, Claudia Espinosa, Todd A Florin, Jeffrey S Gerber, Michelle Gill, Debra L Palazzi, Mark Sawyer, Angela M Statile, Derek J Williams, Sheena Patel, Mark I Neuman, Samir S Shah

Faculty, Staff and Students Publications

As the first part of an update to the clinical practice guideline on the management of community-acquired pneumonia in infants and children older than 3 months of age, we present six updated recommendations. The updated recommendations span the characterization and management of pneumonia with parapneumonic effusion. The panel's recommendations are based on evidence derived from systematic literature reviews and adhere to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach.


2026 Clinical Practice Guideline Update By The Infectious Diseases Society Of America And The Pediatric Infectious Diseases Society On The Management Of Community-Acquired Pneumonia In Infants And Children Older Than 3 Months Of Age: The Use Of Pleural Fluid Drainage Versus Observation, Shawn D St Peter, Krow Ampofo, Thomas Brogan, Michael D Cabana, Claudia Espinosa, Todd A Florin, Jeffrey S Gerber, Michelle Gill, Debra L Palazzi, Mark Sawyer, Angela M Statile, Derek J Williams, Sheena Patel, Mark I Neuman, Samir S Shah Mar 2026

2026 Clinical Practice Guideline Update By The Infectious Diseases Society Of America And The Pediatric Infectious Diseases Society On The Management Of Community-Acquired Pneumonia In Infants And Children Older Than 3 Months Of Age: The Use Of Pleural Fluid Drainage Versus Observation, Shawn D St Peter, Krow Ampofo, Thomas Brogan, Michael D Cabana, Claudia Espinosa, Todd A Florin, Jeffrey S Gerber, Michelle Gill, Debra L Palazzi, Mark Sawyer, Angela M Statile, Derek J Williams, Sheena Patel, Mark I Neuman, Samir S Shah

Faculty, Staff and Students Publications

This paper is part of a larger clinical practice guideline on the diagnosis and management of parapneumonic effusion and empyema in children, developed by the Infectious Diseases Society of America. In this paper, the panel provides recommendations for pleural fluid drainage in children (3 months to 18 years) with parapneumonic effusion and empyema. The panel's recommendations are based upon evidence derived from systematic literature reviews and adhere to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach.


2026 Clinical Practice Guideline Update By The Infectious Diseases Society Of America And The Pediatric Infectious Diseases Society On The Management Of Community-Acquired Pneumonia In Infants And Children Older Than 3 Months Of Age: The Use Of Pleural Fluid Drainage Compared To Surgical Debridement, Shawn D St Peter, Krow Ampofo, Thomas Brogan, Michael D Cabana, Claudia Espinosa, Todd A Florin, Jeffrey S Gerber, Michelle Gill, Debra L Palazzi, Mark Sawyer, Angela M Statile, Derek J Williams, Sheena Patel, Samir S Shah, Mark I Neuman Mar 2026

2026 Clinical Practice Guideline Update By The Infectious Diseases Society Of America And The Pediatric Infectious Diseases Society On The Management Of Community-Acquired Pneumonia In Infants And Children Older Than 3 Months Of Age: The Use Of Pleural Fluid Drainage Compared To Surgical Debridement, Shawn D St Peter, Krow Ampofo, Thomas Brogan, Michael D Cabana, Claudia Espinosa, Todd A Florin, Jeffrey S Gerber, Michelle Gill, Debra L Palazzi, Mark Sawyer, Angela M Statile, Derek J Williams, Sheena Patel, Samir S Shah, Mark I Neuman

Faculty, Staff and Students Publications

This paper is part of a larger clinical practice guideline on the diagnosis and management of parapneumonic effusion and empyema in children, developed by the Infectious Diseases Society of America. In this paper, the panel provides recommendations on the choice of pleural fluid drainage by chest tube with fibrinolysis versus mechanical debridement. The panel's recommendations are based upon evidence derived from systematic literature reviews and adhere to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach.