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Therapeutic Frameworks In Integration Sessions In Substance-Assisted Psychotherapy: A Systematised Review, Sascha B. Thal, Paris Baker, Jonathon Marinis, Michelle Wieberneit, Jason M. Sharbanee, Raimundo Bruno, Petra M. Skeffington, Stephen J. Bright Jan 2023

Therapeutic Frameworks In Integration Sessions In Substance-Assisted Psychotherapy: A Systematised Review, Sascha B. Thal, Paris Baker, Jonathon Marinis, Michelle Wieberneit, Jason M. Sharbanee, Raimundo Bruno, Petra M. Skeffington, Stephen J. Bright

Research outputs 2022 to 2026

Serotonergic psychedelics and related substances have been explored as potential adjuncts in substance-assisted psychotherapy (SAPT) for treating various disorders. SAPT can be divided into three phases: preparation, administration and integration. Integration is commonly defined as the comprehension and effective application of insights from psychedelic experiences into everyday life. However, there is limited research regarding the most appropriate therapeutic approach during SAPT. In this article, we discuss the current evidence for different therapeutic frameworks for integration sessions when serotonergic psychedelics and entactogens are used as adjuncts to psychotherapy. We conducted a systematised review of the literature following PRISMA guidelines and searched …


Transformation At The Cultural Interface: Exploring The Experiences Of Aboriginal And Torres Strait Islander University Students, Braden Hill, Caroline Nilson, Bep Uink, Catherine Fetherston Jan 2023

Transformation At The Cultural Interface: Exploring The Experiences Of Aboriginal And Torres Strait Islander University Students, Braden Hill, Caroline Nilson, Bep Uink, Catherine Fetherston

Research outputs 2022 to 2026

Research on transformative learning (Mezirow, 1991), particularly within the context of higher education, has demonstrated the significant impact university learning can have on a wide range of cohorts across diverse learning contexts. However, the extensive body of literature pertaining to transformative learning remains largely silent on the experiences of Aboriginal and Torres Strait Islander university students and the extent to which their engagement with academia can be transformative. Nevertheless, Nakata’s (2007b) cultural interface theory has shaped policy, practice and thought in Indigenous higher education, elucidating the nuances, complexities and challenges that confront Indigenous students in their journey through university. In …


Utilizing Proteomics To Identify And Optimize Microalgae Strains For High-Quality Dietary Protein: A Review, Sara Hamzelou, Damien Belobrajdic, James A. Broadbent, Angéla Juhász, Kim L. Chang, Ian Jameson, Peter Ralph, Michelle L. Colgrave Jan 2023

Utilizing Proteomics To Identify And Optimize Microalgae Strains For High-Quality Dietary Protein: A Review, Sara Hamzelou, Damien Belobrajdic, James A. Broadbent, Angéla Juhász, Kim L. Chang, Ian Jameson, Peter Ralph, Michelle L. Colgrave

Research outputs 2022 to 2026

Algae-derived protein has immense potential to provide high-quality protein foods for the expanding human population. To meet its potential, a broad range of scientific tools are required to identify optimal algal strains from the hundreds of thousands available and identify ideal growing conditions for strains that produce high-quality protein with functional benefits. A research pipeline that includes proteomics can provide a deeper interpretation of microalgal composition and biochemistry in the pursuit of these goals. To date, proteomic investigations have largely focused on pathways that involve lipid production in selected microalgae species. Herein, we report the current state of microalgal proteome …


Detectable Ctdna At The Time Of Treatment Cessation Of Ipilimumab And Nivolumab For Toxicity Predicts Disease Progression In Advanced Melanoma Patients, Lydia Warburton, Anna Reid, Benhur Amanuel, Leslie Calapre, Michael Millward, Elin Gray Jan 2023

Detectable Ctdna At The Time Of Treatment Cessation Of Ipilimumab And Nivolumab For Toxicity Predicts Disease Progression In Advanced Melanoma Patients, Lydia Warburton, Anna Reid, Benhur Amanuel, Leslie Calapre, Michael Millward, Elin Gray

Research outputs 2022 to 2026

Background: Immune checkpoint inhibition (ICI) has led to unprecedented outcomes for melanoma patients but is associated with toxicity. ICI resumption after high grade irAEs poses a significant challenge in the clinical management of melanoma patients and there are no biomarkers that can help identify patients that might benefit from resuming treatment. This study aims to determine if circulating tumor DNA (ctDNA) levels at the time of treatment-limiting irAE could guide treatment decisions in this clinical context. Methods: This is a retrospective exploratory biomarker study from 34 patients treated with combination ICI for stage IV melanoma. Patients had a treatment-limiting toxicity …


Human In Vivo Medial Gastrocnemius Gear During Active And Passive Muscle Lengthening: Effect Of Inconsistent Methods And Nomenclature On Data Interpretation, Matheus Daros Pinto, Kazunori Nosaka, James M. Wakeling, Anthony J. Blazevich Jan 2023

Human In Vivo Medial Gastrocnemius Gear During Active And Passive Muscle Lengthening: Effect Of Inconsistent Methods And Nomenclature On Data Interpretation, Matheus Daros Pinto, Kazunori Nosaka, James M. Wakeling, Anthony J. Blazevich

Research outputs 2022 to 2026

‘Muscle gear’ is calculated as the ratio of fascicle-to-muscle length change, strain, or velocity. Inconsistencies in nomenclature and definitions of gear exist across disciplines partly due to differences in fascicle [curved (Lf) versus linear (Lf,straight)] and muscle [whole-muscle belly (Lb) versus belly segment (Lb,segment)] length calculation methods. We tested whether these differences affect gear magnitude during passive and active muscle lengthening of human medial gastrocnemius of young men (n=13, 26.3±5.0 years) using an isokinetic dynamometer. Lb, Lb,segment, Lf and Lf,straight were measured from motion analysis and ultrasound imaging data. Downshifts in belly gear but not belly segment gear occurred with …


Building For The Future: A Systematic Review Of The Effects Of Eccentric Resistance Training On Measures Of Physical Performance In Youth Athletes, Thomas E. Bright, Matthew J. Handford, Peter Mundy, Jason Lake, Nicola Theis, Jonathan D. Hughes Jan 2023

Building For The Future: A Systematic Review Of The Effects Of Eccentric Resistance Training On Measures Of Physical Performance In Youth Athletes, Thomas E. Bright, Matthew J. Handford, Peter Mundy, Jason Lake, Nicola Theis, Jonathan D. Hughes

Research outputs 2022 to 2026

Background:

Eccentric resistance training is recognised as an effective stimulus for enhancing measures of muscular strength and power in adult populations; however, its value in youth athletes is currently not well understood.

Objective:

The aim of this systematic review was to critically appraise the effects of eccentric resistance training on measures of physical performance (i.e. muscular strength, jump, sprint and change of direction) in youth athletes 18 years of age and under.

Methods:

Original journal articles published between 1950 and June 2022 were retrieved from electronic search engines of PubMed, SPORTDiscus and Google Scholar’s advanced search option. Full journal articles …


Microvascular And Macrovascular Complications Of Type 2 Diabetes Mellitus: Exome Wide Association Analyses, Afnan Mansour, Mira Mousa, Dima Abdelmannan, Guan Tay, Ahmed Hassoun, Habiba Alsafar Jan 2023

Microvascular And Macrovascular Complications Of Type 2 Diabetes Mellitus: Exome Wide Association Analyses, Afnan Mansour, Mira Mousa, Dima Abdelmannan, Guan Tay, Ahmed Hassoun, Habiba Alsafar

Research outputs 2022 to 2026

Background: Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disorder in which concomitant insulin resistance and β-cell impairment lead to hyperglycemia, influenced by genetic and environmental factors. T2DM is associated with long-term complications that have contributed to the burden of morbidity and mortality worldwide. The objective of this manuscript is to conduct an Exome-Wide Association Study (EWAS) on T2DM Emirati individuals to improve our understanding on diabetes-related complications to improve early diagnostic methods and treatment strategies. Methods: This cross-sectional study recruited 310 Emirati participants that were stratified according to their medically diagnosed diabetes-related complications: diabetic retinopathy, diabetic neuropathy, diabetic …


Nurses’ Perception Of Missed Nursing Care In A Western Australian Teaching Hospital: A Cross-Sectional Study, Afia A. Sarpong, Diana Arabiat, Lucy Gent, Ebenezer Afrifa-Yamoah, Mandy Towell-Barnard Phd, Mnursing Jan 2023

Nurses’ Perception Of Missed Nursing Care In A Western Australian Teaching Hospital: A Cross-Sectional Study, Afia A. Sarpong, Diana Arabiat, Lucy Gent, Ebenezer Afrifa-Yamoah, Mandy Towell-Barnard Phd, Mnursing

Research outputs 2022 to 2026

Background

Missed nursing care (MNC) has gained increasing emphasis in nursing literature because of its association with nurse and patient outcomes in healthcare settings. While missed care has been widely studied, little evidence is available on the types and frequency of missed care, reasons for its occurrence, and predictors of missed care in Western Australia.

Aims

To determine nurses’ perceptions of the types of MNC, reasons for missed care and to identify factors predicting missed care occurrence in Western Australian acute care settings.

Methods

A cross-sectional study in medical and surgical wards was performed. The nurse MISSCARE survey tool was …


Beyond The Stomp: The Nobbs Suzuki Praxis As An Australian Variant Of The Suzuki Method Of Actor Training, Antje Diedrich, Frances Barbe Jan 2023

Beyond The Stomp: The Nobbs Suzuki Praxis As An Australian Variant Of The Suzuki Method Of Actor Training, Antje Diedrich, Frances Barbe

Research outputs 2022 to 2026

This article provides a brief overview of the Nobbs Suzuki Praxis (NSP), an Australian variant of the Suzuki Method of Actor Training (SMAT) developed by John Nobbs in collaboration with Jacqui Carroll from the mid-1990s onwards. After a brief introduction to SMAT and the context in which NSP evolved from it, the article outlines NSP’s key differences in exercise practice and design, particularly in the use of signature physical and vocal tools, and the increased use of structured improvisation within NSP formats. It goes on to examine two concepts specific to NSP–‘feeling’ and ‘opposites and paradox’–and outlines how these enable …


Development And Validation Of The Montreal Cognitive Assessment For People With Hearing Impairment (Moca-H), Piers Dawes, David Reeves, Wai Kent Yeung, Fiona Holland, Anna Pavlina Charalambous, Mathieu Côté, Renaud David, Catherine Helmer, Robert Laforce, Ralph N. Martins, Antonis Politis, Annie Pye, Gregor Russell, Saima Sheikh, Marie-Josée Sirois, Hamid R. Sohrabi, Chyrssoula Thodi, Kathleen Gallant, Ziad Nasreddine, Iracema Leroi Jan 2023

Development And Validation Of The Montreal Cognitive Assessment For People With Hearing Impairment (Moca-H), Piers Dawes, David Reeves, Wai Kent Yeung, Fiona Holland, Anna Pavlina Charalambous, Mathieu Côté, Renaud David, Catherine Helmer, Robert Laforce, Ralph N. Martins, Antonis Politis, Annie Pye, Gregor Russell, Saima Sheikh, Marie-Josée Sirois, Hamid R. Sohrabi, Chyrssoula Thodi, Kathleen Gallant, Ziad Nasreddine, Iracema Leroi

Research outputs 2022 to 2026

Background: Hearing impairment is common among older adults and affects cognitive assessments for identification of dementia which rely on good hearing function. We developed and validated a version of the Montreal Cognitive Assessment (MoCA) for people with hearing impairment. Methods: We adapted existing MoCA 8.1 items for people with hearing impairment by presenting instructions and stimuli in written rather than spoken format. One Attention domain and two Language domain items required substitution by alternative items. Three and four candidate items respectively were constructed and field-tested along with the items adapted to written form. We used a combination of individual item …


Feasibility Of Supervised Telehealth Exercise For Patients With Advanced Melanoma Receiving Checkpoint Inhibitor Therapy, Brendan J. Crosby, Robert U. Newton, Daniel A. Galvão, Dennis R. Taaffe, Pedro Lopez Da Cruz, Tarek M. Meniawy, Muhammad A. Khattak, Wei-Sen Lam, Elin S. Gray, Favil Singh Jan 2023

Feasibility Of Supervised Telehealth Exercise For Patients With Advanced Melanoma Receiving Checkpoint Inhibitor Therapy, Brendan J. Crosby, Robert U. Newton, Daniel A. Galvão, Dennis R. Taaffe, Pedro Lopez Da Cruz, Tarek M. Meniawy, Muhammad A. Khattak, Wei-Sen Lam, Elin S. Gray, Favil Singh

Research outputs 2022 to 2026

Purpose: To determine the feasibility, safety and preliminary efficacy of a telehealth supervised exercise programme in patients with advanced melanoma receiving checkpoint inhibitor therapy. Methods: A 8-week non-randomised feasibility pilot trial utilising a telehealth delivered multimodal exercise programme undertaken thrice weekly with assessments at baseline and post-intervention. The study was considered feasible if there were no severe or life-threatening adverse events as a result of exercise, and three or more of the following criteria were met: the recruitment rate was > 50%, completion rate was > 80%, median programme attendance was > 75%, median exercise compliance > 75%, and average tolerance was > 70%. Preliminary …


Normal Redefined: Exploring Decontextualization Of Lorises (Nycticebus & Xanthonycticebus Spp.) On Social Media Platforms, Luke F. Quarles, Kim Feddema, Marco Campera, K. A.I. Nekaris Jan 2023

Normal Redefined: Exploring Decontextualization Of Lorises (Nycticebus & Xanthonycticebus Spp.) On Social Media Platforms, Luke F. Quarles, Kim Feddema, Marco Campera, K. A.I. Nekaris

Research outputs 2022 to 2026

Introduction: Decontextualization is a concept from psychology whereby new words are learned outside of the context of the here-and-now. Decontextualized language is used for discussing abstract concepts and is crucial to the development of academic language. When it comes to images, a dearth of context can lead to a lack of clarity, such as the use of ambiguous decontextualized images in environmental communication, leading to the promotion of greenwashing. Here we refer to decontextualization as the removal of wildlife from their wild ecological context. Images and videos of globally threatened species are increasingly popular on social media. Showing such taxa …


The Role Of Authentic Leadership On Healthcare Street-Level Bureaucrats’ Well-Being During The Pandemic, Nasim Salehi, Yvonne Brunetto, Tom Dick Jan 2023

The Role Of Authentic Leadership On Healthcare Street-Level Bureaucrats’ Well-Being During The Pandemic, Nasim Salehi, Yvonne Brunetto, Tom Dick

Research outputs 2022 to 2026

This study uses Conservation of Resources Theory, to explain Street-Level Bureaucrats’ (SLBs) workplace behavioural responses to threats to their well-being. We examine whether authentic leadership within street-level organisations positively impacts employee well-being by increasing SLBs’ perception of personal resources, and reducing their perceptions of work harassment. The research design comprises a survey that solicited quantitative and qualitative data from 163 healthcare SLBs working in Australian hospitals during the pandemic in April 2020. Analysis of the means indicates low levels of satisfaction with leadership and low levels of well-being for SLBs. The structural equation modelling findings show that poor leadership is …


Using Qpcr And Microscopy To Assess The Impact Of Harvesting And Weather Conditions On The Relationship Between Alternaria Alternata And Alternaria Spp. Spores In Rural And Urban Atmospheres, Godfrey Philliam Apangu, Carl Alexander Frisk, Beverley Adams-Groom, Geoffrey M. Petch, Mary Hanson, Carsten Ambelas Skjøth Jan 2023

Using Qpcr And Microscopy To Assess The Impact Of Harvesting And Weather Conditions On The Relationship Between Alternaria Alternata And Alternaria Spp. Spores In Rural And Urban Atmospheres, Godfrey Philliam Apangu, Carl Alexander Frisk, Beverley Adams-Groom, Geoffrey M. Petch, Mary Hanson, Carsten Ambelas Skjøth

Research outputs 2022 to 2026

Alternaria is a plant pathogen and human allergen. Alternaria alternata is one of the most abundant fungal spores in the air. The purpose of this study was to examine whether Alternaria spp. spore concentrations can be used to predict the abundance and spatio-temporal pattern of A. alternata spores in the air. This was investigated by testing the hypothesis that A. alternata dominates airborne Alternaria spp. spores and varies spatio-temporally. Secondarily, we aimed at investigating the relationship between airborne Alternaria spp. spores and the DNA profile of A. alternata spores between two proximate (~ 7 km apart) sites. These were examined …


Closing The Shell: Gas-Phase Solvation Of Halides By 1,3-Butadiene, Peter D. Watson, Christian T. Haakansson, Hayden T. Robinson, Timothy R. Corkish, James Brookes, Allan J. Mckinley, Duncan A. Wild Jan 2023

Closing The Shell: Gas-Phase Solvation Of Halides By 1,3-Butadiene, Peter D. Watson, Christian T. Haakansson, Hayden T. Robinson, Timothy R. Corkish, James Brookes, Allan J. Mckinley, Duncan A. Wild

Research outputs 2022 to 2026

Gas-phase solvation of halides by 1,3-butadiene has been studied via a combination of photoelectron spectroscopy and density functional theory. Photoelectron spectra for X−⋯(C4H6)n (X=Cl, Br, I where n=1-3, 1–3 and 1–7 respectively) are presented. For all complexes, the calculated structures indicate that butadiene is bound in a bidentate fashion through hydrogen-bonding, with the chloride complex showing the greatest degree of stabilisation of the internal C−C rotation of cis-butadiene. In both Cl− and Br− complexes, the first solvation shell is shown to be at least n = 4 from the vertical detachment energies (VDEs), however for I−, increases in the …


Instantaneous Frequency Estimation Of Fm Signals Under Gaussian And Symmetric Alpha-Stable Noise: Deep Learning Versus Time-Frequency Analysis, Huda Saleem Razzaq, Zahir M. Hussain Jan 2023

Instantaneous Frequency Estimation Of Fm Signals Under Gaussian And Symmetric Alpha-Stable Noise: Deep Learning Versus Time-Frequency Analysis, Huda Saleem Razzaq, Zahir M. Hussain

Research outputs 2022 to 2026

Deep learning (DL) and machine learning (ML) are widely used in many fields but rarely used in the frequency estimation (FE) and slope estimation (SE) of signals. Frequency and slope estimation for frequency-modulated (FM) and single-tone sinusoidal signals are essential in various applications, such as wireless communications, sound navigation and ranging (SONAR), and radio detection and ranging (RADAR) measurements. This work proposed a novel frequency estimation technique for instantaneous linear FM (LFM) sinusoidal wave using deep learning. Deep neural networks (DNN) and convolutional neural networks (CNN) are classes of artificial neural networks (ANNs) used for the frequency and slope estimation …


Women’S Views On Obstetric Fistula Risk Factors And Prevention In North-Central Nigeria: An Interpretive Descriptive Study, Lydia Babatunde Bulndi, Deborah Ireson, Esther Adama, Sara Bayes Jan 2023

Women’S Views On Obstetric Fistula Risk Factors And Prevention In North-Central Nigeria: An Interpretive Descriptive Study, Lydia Babatunde Bulndi, Deborah Ireson, Esther Adama, Sara Bayes

Research outputs 2022 to 2026

Objective: Obstetric fistula, also known as vesicovaginal fistula or rectovaginal fistula, is an abnormal opening between the vagina and rectum caused by prolonged obstructed labour that causes substantial long-term harm to women. It is most prevalent in low resource settings and although preventative measures have been proposed, they have not, to date, taken women’s own views into account. The objective of this study was to explore the views of North Nigerian women on obstetric fistula risk factors and prevention.

Design: This study was conducted using Interpretive Description methodology, which is a qualitative approach underpinned by Symbolic Interactionism. A semistructured questionnaire …


Association Between Micronutrients, Oxidative Stress Biomarkers And Angiogenic Growth Mediators In Early And Late-Onset Preeclamptic Ghanaian Women, Enoch O. Anto, Wina I. O. Boadu, Otchere Addai-Mensah, Yaw A. Wiafe, William K. B. A. Owiredu, Christian Obirikorang, Max E. Annani-Akollor, Eric Adua, Michael Appiah, Stephen Opoku, Emmanuel Acheampong, Evans A. Asamoah, Eddie W. Owiredu, Agartha O. Anto, Augustine Tawiah, Frank Ankobea, Ebenezer Afrifa Yamoah, David A. Coall Jan 2023

Association Between Micronutrients, Oxidative Stress Biomarkers And Angiogenic Growth Mediators In Early And Late-Onset Preeclamptic Ghanaian Women, Enoch O. Anto, Wina I. O. Boadu, Otchere Addai-Mensah, Yaw A. Wiafe, William K. B. A. Owiredu, Christian Obirikorang, Max E. Annani-Akollor, Eric Adua, Michael Appiah, Stephen Opoku, Emmanuel Acheampong, Evans A. Asamoah, Eddie W. Owiredu, Agartha O. Anto, Augustine Tawiah, Frank Ankobea, Ebenezer Afrifa Yamoah, David A. Coall

Research outputs 2022 to 2026

Objectives: Micronutrients, especially calcium (Ca) and magnesium (Mg) are reported to reduce preeclampsia events via several factors such as endothelial cell control, optimal oxidative stress and a balanced angiogenic growth mediator. We evaluated the association of micronutrients with oxidative stress biomarkers, and angiogenic growth mediators in early-onset preeclampsia and late-onset preeclampsia. Methods: This case-control study recruited 197 preeclampsia (early-onset preeclampsia = 70 and late-onset preeclampsia = 127) as cases and 301 normotensive pregnant women as controls from the Komfo Anokye Teaching Hospital, Ghana. Samples were collected after 20 weeks of gestation for both cases and controls and estimated for Ca, …


Development Of A Standardised System To Classify Injury-Inciting Circumstances In Football: The Football Injury Inciting Circumstances Classification System (Fiiccs), Francesco Aiello, Alan Mccall, Susan J. Brown, Andreas Serner, Lauren V. Fortington, Suzanne A. E. Huurman, Colin Lewin, Masashi Nagao, James O’Brien, Anastasia Panossian, Ricard Pruna, Guilherme P. Ramos, Matthew Whalan, Franco M. Impellizzeri Jan 2023

Development Of A Standardised System To Classify Injury-Inciting Circumstances In Football: The Football Injury Inciting Circumstances Classification System (Fiiccs), Francesco Aiello, Alan Mccall, Susan J. Brown, Andreas Serner, Lauren V. Fortington, Suzanne A. E. Huurman, Colin Lewin, Masashi Nagao, James O’Brien, Anastasia Panossian, Ricard Pruna, Guilherme P. Ramos, Matthew Whalan, Franco M. Impellizzeri

Research outputs 2022 to 2026

Background: A comprehensive examination of the sport-specific activities and circumstances being performed at the time of injury is important to hypothesise mechanisms, develop prevention strategies and inform future investigations. Results reported in the literature are inconsistent because inciting activities are reported using different classifications. Hence the aim was to develop a standardised system for the reporting of inciting circumstances. Methods: The system was developed using a modified Nominal Group Technique. The initial panel included 12 sports practitioners and researchers from four continents with respectively ≥ 5 years of experience working in professional football and/or conducting injury research. The process consisted …


Three-Dimensional Food Printing: Its Readiness For A Food And Nutrition Insecure World, Liezhou Zhong, Joshua R. Lewis, Marc Sim, Catherine P. Bondonno, Mark L. Wahlqvist, Amin Mugera, Sharon Purchase, Kadambot H. M. Siddique, Michael J. Considine, Stuart K. Johnson, Amanda Devine, Jonathan M. Hodgson Jan 2023

Three-Dimensional Food Printing: Its Readiness For A Food And Nutrition Insecure World, Liezhou Zhong, Joshua R. Lewis, Marc Sim, Catherine P. Bondonno, Mark L. Wahlqvist, Amin Mugera, Sharon Purchase, Kadambot H. M. Siddique, Michael J. Considine, Stuart K. Johnson, Amanda Devine, Jonathan M. Hodgson

Research outputs 2022 to 2026

Three-dimensional (3D) food printing is a rapidly emerging technology offering unprecedented potential for customised food design and personalised nutrition. Here, we evaluate the technological advances in extrusion-based 3D food printing and its possibilities to promote healthy and sustainable eating. We consider the challenges in implementing the technology in real-world applications. We propose viable applications for 3D food printing in health care, health promotion and food waste upcycling. Finally, we outline future work on 3D food printing in food safety, acceptability and economics, ethics and regulations. . .


Habitual Dietary Nitrate Intake And Cognition In The Australian Imaging, Biomarkers And Lifestyle Study Of Ageing: A Prospective Cohort Study, Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie Rainey-Smith, Samantha Gardener, Lauren Blekkenhorst, David Ames, Paul Maruff, Ralph Martins, Jonathan M. Hodgson, Catherine P. Bondonno, Australian Imaging, Biomarkers And Lifestyle Group Jan 2023

Habitual Dietary Nitrate Intake And Cognition In The Australian Imaging, Biomarkers And Lifestyle Study Of Ageing: A Prospective Cohort Study, Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie Rainey-Smith, Samantha Gardener, Lauren Blekkenhorst, David Ames, Paul Maruff, Ralph Martins, Jonathan M. Hodgson, Catherine P. Bondonno, Australian Imaging, Biomarkers And Lifestyle Group

Research outputs 2022 to 2026

Background & aims

Dietary nitrate improves cardiovascular health via a nitric oxide (NO) pathway. NO is key to both cardiovascular and brain health. There is also a strong association between vascular risk factors and brain health. Dietary nitrate intake could therefore be associated with better cognitive function and reduced risk of cognitive decline. This is yet to be investigated. The aim of this study was to investigate the association between habitual intake of dietary nitrate from sources where nitrate is naturally present, and cognitive function, and cognitive decline, in the presence or absence of the apolipoprotein E (APOE) …


Machine Learning For Abdominal Aortic Calcification Assessment From Bone Density Machine-Derived Lateral Spine Images, Naeha Sharif, Syed Zulqarnain Gilani, David Suter, Siobhan Reid, Pawel Szulc, Douglas Kimelman, Mohammad Jafari Jozani, Jonathan M. Hodgson, Marc Sim, Kun Zhu, Nicholas C. Harvey, Douglas P. Kiel, Richard L. Prince, John T. Schousboe, William D. Leslie, Joshua R. Lewis Jan 2023

Machine Learning For Abdominal Aortic Calcification Assessment From Bone Density Machine-Derived Lateral Spine Images, Naeha Sharif, Syed Zulqarnain Gilani, David Suter, Siobhan Reid, Pawel Szulc, Douglas Kimelman, Mohammad Jafari Jozani, Jonathan M. Hodgson, Marc Sim, Kun Zhu, Nicholas C. Harvey, Douglas P. Kiel, Richard L. Prince, John T. Schousboe, William D. Leslie, Joshua R. Lewis

Research outputs 2022 to 2026

Background

Lateral spine images for vertebral fracture assessment can be easily obtained on modern bone density machines. Abdominal aortic calcification (AAC) can be scored on these images by trained imaging specialists to assess cardiovascular disease risk. However, this process is laborious and requires careful training.

Methods

Training and testing of model performance of the convolutional neural network (CNN) algorithm for automated AAC-24 scoring utilised 5012 lateral spine images (2 manufacturers, 4 models of bone density machines), with trained imaging specialist AAC scores. Validation occurred in a registry-based cohort study of 8565 older men and women with images captured as part …


A Vulnerability Approach To Irregular Migration And Modern Slavery In Australia, Jamal Barnes, Mostafa M. Naser, Joshua Aston Jan 2023

A Vulnerability Approach To Irregular Migration And Modern Slavery In Australia, Jamal Barnes, Mostafa M. Naser, Joshua Aston

Research outputs 2022 to 2026

It is widely recognised that migrants and irregular migrants are at risk of modern slavery and slavery-like practices worldwide. As migrants and irregular migrants make their way across state borders, or reach their destination countries, they have been victim to practices such as forced labour, exploitation, wage theft, torture and inhuman treatment and sexual servitude, among other practices. Australia is no exception, with just under 300 cases of modern slavery reported to the Australian Federal Police between 2021 and 2022. Although Australia has acted to stop slavery and slavery-like practices, it has focused on a law enforcement response, ignoring the …


Ageing Reduces Persistent Inward Current Contribution To Motor Neurone Firing: Potential Mechanisms And The Role Of Exercise, Lucas B. R. Orssatto, Anthony J. Blazevich, Gabriel S. Trajano Jan 2023

Ageing Reduces Persistent Inward Current Contribution To Motor Neurone Firing: Potential Mechanisms And The Role Of Exercise, Lucas B. R. Orssatto, Anthony J. Blazevich, Gabriel S. Trajano

Research outputs 2022 to 2026

Nervous system deterioration is a primary driver of age-related motor impairment. The motor neurones, which act as the interface between the central nervous system and the muscles, play a crucial role in amplifying excitatory synaptic input to produce the desired motor neuronal firing output. For this, they utilise their ability to generate persistent (long-lasting) depolarising currents that increase cell excitability, and both amplify and prolong the output activity of motor neurones for a given synaptic input. Modulation of these persistent inward currents (PICs) contributes to the motor neurones’ capacities to attain the required firing frequencies and rapidly modulate them to …


Economic Evaluation Of The Very Early Rehabilitation In Speech (Verse) Intervention, J. Kim, G. Sookram, Erin Godecke, Emily Louise Brogan, Elizabeth Armstrong, F. Ellery, T. Rai, M. L. Rose, Natalie Ciccone, S. Middleton, A. Holland, G. J. Hankey, J. Bernhardt, D. A. Cadilhac Jan 2023

Economic Evaluation Of The Very Early Rehabilitation In Speech (Verse) Intervention, J. Kim, G. Sookram, Erin Godecke, Emily Louise Brogan, Elizabeth Armstrong, F. Ellery, T. Rai, M. L. Rose, Natalie Ciccone, S. Middleton, A. Holland, G. J. Hankey, J. Bernhardt, D. A. Cadilhac

Research outputs 2022 to 2026

Introduction: There is limited evidence on the costs and outcomes of patients with aphasia after stroke. The aim of this study was to estimate costs in patients with aphasia after stroke according to the aphasia therapies provided.

Methods: A three-arm, prospective, randomized, parallel group, open-label, blinded endpoint assessment trial conducted in Australia and New Zealand. Usual ward-based care (Usual Care) was compared to additional usual ward-based therapy (Usual Care Plus) and a prescribed and structured aphasia therapy program in addition to Usual Care (the VERSE intervention). Information about healthcare utilization and productivity were collected to estimate costs in Australian dollars …


Edna Metabarcoding Of Avocado Flowers: ‘Hass’ It Got Potential To Survey Arthropods In Food Production Systems?, Joshua H. Kestel, Philip W. Bateman, David L. Field, Nicole E. White, Rose Lines, Paul Nevill Jan 2023

Edna Metabarcoding Of Avocado Flowers: ‘Hass’ It Got Potential To Survey Arthropods In Food Production Systems?, Joshua H. Kestel, Philip W. Bateman, David L. Field, Nicole E. White, Rose Lines, Paul Nevill

Research outputs 2022 to 2026

In the face of global biodiversity declines, surveys of beneficial and antagonistic arthropod diversity as well as the ecological services that they provide are increasingly important in both natural and agro-ecosystems. Conventional survey methods used to monitor these communities often require extensive taxonomic expertise and are time-intensive, potentially limiting their application in industries such as agriculture, where arthropods often play a critical role in productivity (e.g. pollinators, pests and predators). Environmental DNA (eDNA) metabarcoding of a novel substrate, crop flowers, may offer an accurate and high throughput alternative to aid in the detection of these managed and unmanaged taxa. Here, …


Effects Of Submaximal And Supramaximal Accentuated Eccentric Loading On Mass And Function, Sergio Maroto-Izquierdo, Fernando Martín-Rivera, Kazunori Nosaka, Marco Beato, Javier González-Gallego, José A. De Paz Jan 2023

Effects Of Submaximal And Supramaximal Accentuated Eccentric Loading On Mass And Function, Sergio Maroto-Izquierdo, Fernando Martín-Rivera, Kazunori Nosaka, Marco Beato, Javier González-Gallego, José A. De Paz

Research outputs 2022 to 2026

Introduction: Eccentric-overload (EO) resistance training emerges as an alternative to more optimally prescribe intensity relative to the force generation capabilities of the eccentric muscle contraction. Given the difficulties to individually prescribe absolute eccentric loads relative to each person’s eccentric ability, setting the load relative to the concentric one-repetition maximum (1-RM) is the most used EO training approach. Therefore, we investigated the effects of submaximal and supramaximal (i.e., eccentric loads above 100% of 1-RM) accentuated eccentric training on changes in lean mass, anabolic hormonal responses and muscle function. Methods: Physically active university students (n = 27) were randomly assigned to two …


Female Athlete Health Domains: A Supplement To The International Olympic Committee Consensus Statement On Methods For Recording And Reporting Epidemiological Data On Injury And Illness In Sport, Isabel S. Moore, Kay M. Crossley, Kari Bo, Margo Mountjoy, Kathryn E. Ackerman, Juliana D. S. Antero, Jorunn S. Borgen, Wendy J. Brown, Caroline S. Bolling, Benjamin Clarsen, Wayne Derman, Paul Dijkstra, Amber Donaldson, Kirsty J. Elliott-Sale, Carolyn A. Emery, Lene Haakstad, Astrid Junge, Nonhlanhla S. Mkumbuzi, Sophia Nimphius, Debbie Palmer, Mireille Van Poppel, Jane S. Thornton, Rita Tomás, Phathokuhle C. Zondi, Evert Verhagen Jan 2023

Female Athlete Health Domains: A Supplement To The International Olympic Committee Consensus Statement On Methods For Recording And Reporting Epidemiological Data On Injury And Illness In Sport, Isabel S. Moore, Kay M. Crossley, Kari Bo, Margo Mountjoy, Kathryn E. Ackerman, Juliana D. S. Antero, Jorunn S. Borgen, Wendy J. Brown, Caroline S. Bolling, Benjamin Clarsen, Wayne Derman, Paul Dijkstra, Amber Donaldson, Kirsty J. Elliott-Sale, Carolyn A. Emery, Lene Haakstad, Astrid Junge, Nonhlanhla S. Mkumbuzi, Sophia Nimphius, Debbie Palmer, Mireille Van Poppel, Jane S. Thornton, Rita Tomás, Phathokuhle C. Zondi, Evert Verhagen

Research outputs 2022 to 2026

The IOC made recommendations for recording and reporting epidemiological data on injuries and illness in sports in 2020, but with little, if any, focus on female athletes. Therefore, the aims of this supplement to the IOC consensus statement are to (i) propose a taxonomy for categorisation of female athlete health problems across the lifespan; (ii) make recommendations for data capture to inform consistent recording and reporting of symptoms, injuries, illnesses and other health outcomes in sports injury epidemiology and (iii) make recommendations for specifications when applying the Strengthening the Reporting of Observational Studies in Epidemiology-Sport Injury and Illness Surveillance (STROBE-SIIS) …


How General Practitioners And Patients Discuss Type 2 Diabetes Mellitus And Cardiovascular Diseases Concerns During Consultations: Implications For Digital Health, Urvashi Rohilla, Jayashanthi P. Ramarao, Jared Lane, Neha N. Khatri, James Smith, Kathleen Yin, Annie Y. S. Lau Jan 2023

How General Practitioners And Patients Discuss Type 2 Diabetes Mellitus And Cardiovascular Diseases Concerns During Consultations: Implications For Digital Health, Urvashi Rohilla, Jayashanthi P. Ramarao, Jared Lane, Neha N. Khatri, James Smith, Kathleen Yin, Annie Y. S. Lau

Research outputs 2022 to 2026

Objective: To analyse general practitioner–patient consultations about type 2 diabetes mellitus or cardiovascular diseases and describe (i) the nature of self-management discussions; (ii) actions required from patients during and after consultation regarding self-management; and (iii) implications for digital health to support patients during (and after) consultation. Method: This study screened 281 general practitioner consultations conducted in 2017 within the UK general practice setting from an existing dataset containing videos and transcripts of consultations between GPs and patients. Secondary analysis was conducted using a multi-method approach, including descriptive, content, and visualisation analysis, to inform the nature of self-management discussions, what actions …


It's Quite Good Fun: A Qualitative Study Of A Singing/Songwriting Programme For People With Parkinson's Disease And Their Spouses, Deborah Hersh, Shi J. Kong, Jessica Smith Jan 2023

It's Quite Good Fun: A Qualitative Study Of A Singing/Songwriting Programme For People With Parkinson's Disease And Their Spouses, Deborah Hersh, Shi J. Kong, Jessica Smith

Research outputs 2022 to 2026

Background: : Group singing for people with Parkinson's disease (PD) is an established intervention not only to improve voice and speech difficulties but also for emotional and social benefit. Less is known about the experiences of group singing on the couple—the person with PD and their spouse or partner together—and studies have not specifically tracked impact through time or in combination with songwriting. Aims: : To understand the impact of group singing/songwriting on couples (participants with PD and their spouses) to unpack whether this broader view might help explain why such interventions are reported as beneficial. Using a trajectory approach, …