Digital Commons Network^™

Modelling The Spatial Risk Pattern Of Dementia In Denmark Using Residential Location Data: A Registry-Based National Cohort, Prince M. Amegbor, Clive E. Sabel, Laust H. Mortensen, Amar J. Mehta

School of Geography, Earth and Environmental Sciences

Dementia is a major global public health concern that is increasingly leading to morbidity and mortality among older adults. While studies have focused on the risk factors and care provision, there is currently limited knowledge about the spatial risk pattern of the disease. In this study, we employ Bayesian spatial modelling with a stochastic partial differential equation (SPDE) approach to model the spatial risk using complete residential history data from the Danish population and health registers. The study cohort consisted of 1.6 million people aged 65 years and above from 2005 to 2018. The results of the spatial risk map …

Cheating And The Effect Of Promises In Indian And German Children, Patricia Kanngiesser, Jahnavi Sunderarajan, Jan K. Woike

School of Psychology

Cheating is harmful to others and society at large. Promises have been shown to increase honesty in children, but their effectiveness has not been compared between different cultural contexts. In a study (2019) with 7- to 12-year-olds (N = 406, 48% female, middle-class), voluntary promises reduced cheating in Indian, but not in German children. Children in both contexts cheated, but cheating rates were lower in Germany than in India. In both contexts, cheating decreased with age in the (no-promise) control condition and was unaffected by age in the promise condition. These findings suggest that there may exist a threshold beyond …

“We’Ve All Come Together”: A Board Game Intervention For Children And Adults With Autism And Other Developmental Disabilities, Gray Atherton, Emily Dawson, Liam Cross

School of Psychology

The authors discuss how board games offer individuals with autism (whooften struggle with social settings and require structured outlets for building relationships) an affordable, naturalistic, collaborative environmentthat is stimulating, engaging, and educational. Board games, they assert,provide opportunities to practice social skills, including cooperation andsocial deduction, essential skills for both neurotypical and atypical people.The authors include recommendations for introducing board games intospecial educational settings. K

Tackling Loneliness Together: A Three-Tier Social Identity Framework For Social Prescribing, S. Alexander Haslam, Catherine Haslam, Tegan Cruwys, Leah S. Sharman, Shaun Hayes, Zoe Walter, Jolanda Jetten, Niklas K. Steffens, Magnolia Cardona, Crystal J. La Rue, Niamh Mcnamara, Blerina Këllezi, Juliet R.H. Wakefield, Clifford Stevenson, Mhairi Bowe, Peter Mcevoy, Alysia M. Robertson, Mark Tarrant, Genevieve Dingle, Tarli Young

School of Psychology

In recent years, there has been growing recognition of the threats to health posed by loneliness. One of the main strategies that has been recommended to address this is social prescribing (SP). This typically involves general practitioners (GPs) and other health practitioners directing clients who are experiencing loneliness and related conditions to take part in social activities—typically in recreational and community contexts. However, evidence for the effectiveness of SP is mixed—leading some to suggest that enthusiasm for it might be misplaced. In this review, we argue that a core problem with most existing approaches to SP is that they lack …

Professionalism In Artificial Intelligence: The Link Between Technology And Ethics, Anton Klarin, Hossein Ali Abadi, Rifat Sharmelly

Research outputs 2022 to 2026

Ethical conduct of artificial intelligence (AI) is undoubtedly becoming an ever more pressing issue considering the inevitable integration of these technologies into our lives. The literature so far discussed the responsibility domains of AI; this study asks the question of how to instil ethicality into AI technologies. Through a three-step review of the AI ethics literature, we find that (i) the literature is weak in identifying solutions in ensuring ethical conduct of AI, (ii) the role of professional conduct is underexplored, and (iii) based on the values extracted from studies about AI ethical breaches, we thus propose a conceptual framework …

Staff Perceptions On The Effectiveness Of Grip-S, A New Approach To Clinical Supervision Incorporating Safewards: An Interpretive Phenomenological Analysis, Jennifer Hamilton, Amanda Cole, Richard Bostwick, Irene Ngune

Research outputs 2022 to 2026

This study explored the impact of an innovative approach to clinical supervision for mental health nurses which integrates Safewards, named Group Reflective integrated Practice with Safewards–GRiP-S. Qualitative data was collected through 10 individual semi-structured interviews with nursing staff who had participated within the clinical supervision approach. Interviews provided insights into the nursing staff’s perception and experience of the clinical supervision approach. Through interpretive phenomenological analysis six themes emerged (i) illuminating embodied practice of Safewards, (ii) building confidence through empowering connections, (iii) creating a culture of positive change, (iv) identifying internal motivation for and external barriers to supervision engagement, (v) navigating …

Does Intrauterine Exposure To Diabetes Impact Mental And Motor Skills? A Meta-Analysis Of The Bayley Scales Of Infant Development, Diana Arabiat, Mahammad Al Jabery, Lisa Whitehead

Research outputs 2022 to 2026

Background: Attempts to conduct meta-analyses of the association between child development and diabetes have been limited by the wide range of tools and definitions of developmental outcomes used in the literature. We aim to meta-analyze a widely used measure of child development, the Bayley Scales of Infant Development, with respect to exposure to diabetes and developmental scores. Methods: PsycINFO, MEDLINE/PubMed, EMBASE, Emcare, and Google Scholar databases were searched. Two independent reviewers screened, extracted, and quality-appraised the studies using JBI SUMARI software. Forest plots were created with the standardized mean difference using the random-effects model, and heterogeneity was assessed using I2. …

Pdf Malware Detection: Toward Machine Learning Modeling With Explainability Analysis, G. M.Sakhawat Hossain, Kaushik Deb, Helge Janicke, Iqbal H. Sarker

Research outputs 2022 to 2026

The Portable Document Format (PDF) is one of the most widely used file types, thus fraudsters insert harmful code into victims' PDF documents to compromise their equipment. Conventional solutions and identification techniques are often insufficient and may only partially prevent PDF malware because of their versatile character and excessive dependence on a certain typical feature set. The primary goal of this work is to detect PDF malware efficiently in order to alleviate the current difficulties. To accomplish the goal, we first develop a comprehensive dataset of 15958 PDF samples taking into account the non-malevolent, malicious, and evasive behaviors of the …

The Quest For Continuous Quality Improvement In Australian Long Day Care Services: Getting The Most Out Of The Assessment And Rating Process, Susan L. Irvine, Lennie Barblett, Manjula Waniganayake, Fay Hadley, Rebecca Andrews, Maria Hatzigianni, Hui Li, Leanne Lavina, Linda J. Harrison, Belinda Davis

Research outputs 2022 to 2026

The National Quality Framework (NQF) was intended to drive continuous improvement in education and care services in Australia. Ten years into implementation, the effectiveness of the NQF is demonstrated by steady improvements in quality as measured against the National Quality Standard (NQS). The process of assessing and rating services is a key element in the NQF, drawing together regulatory compliance and quality assurance. This paper draws on findings from a national Quality Improvement Research Project investigating the characteristics, processes, challenges and enablers of quality improvement in long day care services, concentrating on Quality Area 1 Educational program and practice and …

Navigating The Intersection Between Academic And Research Integrity For Investigations Involving Research Students. Practitioner Experiences At An Australian University, Marc Fellman

Research outputs 2022 to 2026

There is limited research on the intersection between research and academic integrity in scenarios concerning research students. In this commentary the experiences of a practitioner working in research governance, navigating the interstices between research integrity (RI) and academic integrity (AI) investigations, will be examined. With a view to promoting discussion on this aspect of research governance.

Empowering Pro-Environmental Potential Among Hotel Employees: Insights From Self-Determination Theory, Ataul K. Patwary, S. M. Rasoolimanesh, Mohd H. Hanafiah, Roslizawati C. Aziz, Ahmad E. Mohamed, Muhammad U. Ashraf, Nor R. A. N. Azam

Research outputs 2022 to 2026

Purpose: This research examines the role of green, inclusive leadership, corporate social responsibility, and pro-environmental attitudes on proactive pro-environmental behaviour among hotel employees. It further examines the indirect effects of pro-environmental attitudes between green inclusive leadership, corporate social responsibility, and proactive pro-environmental behaviour, as well as the moderating role of psychological contract breach between pro-environmental attitudes and proactive pro-environmental behaviour.

Design/methodology/approach: The participants of this cross-sectional study were employees in the Malaysian hotel industry, and 374 usable questionnaires were used for data analysis. The data were analysed using Partial Least Squares – Structural Equation Modelling.

Findings: This study found that …

First-Line Chemoimmunotherapy And Immunotherapy In Patients With Non-Small Cell Lung Cancer And Brain Metastases: A Registry Study, Lauren J. Brown, Victor Khou, Chris Brown, Marliese Alexander, Dasantha Jayamanne, Joe Wei, Lauren Gray, Wei Chan, Samuel Smith, Susan Harden, Antony Mersiades, Lydia Warburton, Malinda Itchins, Jenny H. Lee, Nick Pavlakis, Stephen J. Clarke, Michael Boyer, Adnan Nagrial, Eric Hau, Ines Pires Da Silva, Steven Kao, Benjamin Y. Kong

Research outputs 2022 to 2026

Introduction: Brain metastases commonly occur in patients with non-small cell lung cancer (NSCLC). Standard first-line treatment for NSCLC, without an EGFR, ALK or ROS1 mutation, is either chemoimmunotherapy or anti-PD-1 monotherapy. Traditionally, patients with symptomatic or untreated brain metastases were excluded from the pivotal clinical trials that established first-line treatment recommendations. The intracranial effectiveness of these treatment protocols has only recently been elucidated in small-scale prospective trials. Methods: Patients with NSCLC and brain metastases, treated with first-line chemoimmunotherapy or anti-PD-1 monotherapy were selected from the Australian Registry and biObank of thoracic cancers (AURORA) clinical database covering seven institutions. The primary …

A Comprehensive Multi-Omics Analysis Reveals Unique Signatures To Predict Alzheimer’S Disease, Michael Vacher, Rodrigo Canovas, Simon M. Laws, James D. Doecke

Research outputs 2022 to 2026

Background: Complex disorders, such as Alzheimer’s disease (AD), result from the combined influence of multiple biological and environmental factors. The integration of high-throughput data from multiple omics platforms can provide system overviews, improving our understanding of complex biological processes underlying human disease. In this study, integrated data from four omics platforms were used to characterise biological signatures of AD. Method: The study cohort consists of 455 participants (Control:148, Cases:307) from the Religious Orders Study and Memory and Aging Project (ROSMAP). Genotype (SNP), methylation (CpG), RNA and proteomics data were collected, quality-controlled and pre-processed (SNP = 130; CpG = 83; RNA …

Accelerating The Exploration Of High-Entropy Alloys: Synergistic Effects Of Integrating Computational Simulation And Experiments, Deyu Jiang, Yuhua Li, Liqiang Wang, Lai Chang Zhang

Research outputs 2022 to 2026

High-entropy alloys (HEAs) are novel materials composed of multiple elements with nearly equal concentrations and they exhibit exceptional properties such as high strength, ductility, thermal stability, and corrosion resistance. However, the intricate and diverse structures of HEAs pose significant challenges to understanding and predicting their behavior at different length scales. This review summarizes recent advances in computational simulations and experiments of structure-property relationships in HEAs at the nano/micro scales. Various methods such as first-principles calculations, molecular dynamics simulations, phase diagram calculations, and finite element simulations are discussed for revealing atomic/chemical and crystal structures, defect formation and migration, diffusion and phase …

Acidophile Microbiology: From Extreme Environments To Biotechnological Applications, Elizabeth L.J. Watkin, Ivan Nancucheo, Axel Schippers

Research outputs 2022 to 2026

No abstract provided.

Grain Boundary Engineering: An Emerging Pathway Toward Efficient Electrocatalysis, Xiaomin Xu, Yijun Zhong, Magdalena Wajrak, Tejas Bhatelia, San Ping Jiang, Zongping Shao

Research outputs 2022 to 2026

Electrochemical transformation processes involving carbon, hydrogen, oxygen, nitrogen, and small-molecule chemistries represent a promising means to store renewable energy sources in the form of chemical energy. However, their widespread deployment is hindered by a lack of efficient, selective, durable, and affordable electrocatalysts. Recently, grain boundary (GB) engineering as one category of defect engineering, has emerged as a viable and powerful pathway to achieve improved electrocatalytic performances. This review presents a timely and comprehensive overview of recent advances in GB engineering for efficient electrocatalysis. The beneficial effects of introducing GBs into electrocatalysts are discussed, followed by an overview of the synthesis …

It Takes It Out Of The Textbook: Benefits Of And Barriers To Expert By Experience Involvement In Pre-Registration Mental Health Nursing Education, Brenda Happell, Sarah Gordon, John Hurley, Kim Foster, Mike Hazelton, Richard Lakeman, Lorna Moxham, Terri Warner

Research outputs 2022 to 2026

What Is Known on the Subject?: Service user involvement in mental health nursing education is beneficial in terms of attitudinal change to reduce stigma, clinical skill development and enhancing understandings of recovery-oriented practice. Service users as experts by experience have not been embedded within pre-registration nursing programs. Consequently, they remain limited in number, ad hoc and frequently tokenistic. Nurse academics responsible for the design and delivery of pre-registration mental health nursing curricula have a potentially important role in facilitating expert by experience involvement in mental health nursing education. What this Paper Adds to Existing Knowledge: Nurse academics teaching mental health …

Psychedelic Trip Sitting, Dosages And Intensities: Supplementing Clinical Studies With Anecdotal Reports, Liam B. Engel, Sascha Thal, Stephen J. Bright, Mitchell Low

Research outputs 2022 to 2026

Background and aims: Online communities provide insights into psychedelic consumption, assisting in identification of trends, informing both harm reduction provisions and clinical research. This study extracts forum data on psychedelic substances, dosages, and administration routes, categorising and analysing self-reported consumption to inform care services and guide clinical work with psychedelics. Methods: Posts (n = 660) from online psychedelic forums (The Shroomery and DMT Nexus) on 'trip sitting' were analysed. Using a Delphi-style expert panel review facilitated by LE, we created drug weight and intensity charts (threshold, light, common, strong and heavy dosages) for psychedelics discussed in these posts. The psychedelic …

Rationale, Design, And Baseline Characteristics Of Participants In The Health@Nus Mhealth Augmented Cohort Study Examining Student-To-Work Life Transition: Protocol For A Prospective Cohort Study, Xin Hui Chua, Sarah Martine Edney, Andre Matthias Müller, Nicholas A. Petrunoff, Clare Whitton, Zoey Tay, Claire Marie Jie Lin Goh, Bozhi Chen, Su Hyun Park, Salome A. Rebello, Alicia Low, Janelle Chia, Daphne Koek, Karen Cheong, Rob M. Van Dam, Falk Müller-Riemenschneider

Research outputs 2022 to 2026

Background: Integration of mobile health data collection methods into cohort studies enables the collection of intensive longitudinal information, which gives deeper insights into individuals’ health and lifestyle behavioral patterns over time, as compared to traditional cohort methods with less frequent data collection. These findings can then fill the gaps that remain in understanding how various lifestyle behaviors interact as students graduate from university and seek employment (student-to-work life transition), where the inability to adapt quickly to a changing environment greatly affects the mental well-being of young adults. Objective: This paper aims to provide an overview of the study methodology and …

The Caregiving Role Influences Suboptimal Health Status And Psychological Symptoms In Unpaid Carers, Monique Garcia, Zheng Guo, Yulu Zheng, Zhiyuan Wu, Ethan Visser, Lois Balmer, Wei Wang

Research outputs 2022 to 2026

Background: Suboptimal Health Status (SHS) is the physical state between health and disease. This study aimed to fill in the knowledge gap by investigating the prevalence of SHS and psychological symptoms among unpaid carers and to identify SHS-risk factors from the perspective of predictive, preventive and personalised medicine (PPPM). Methods: A cross-sectional study was conducted among 368 participants who were enrolled from Australia, including 203 unpaid carers as cases and 165 individuals from the general population as controls. SHS scores were measured using SHSQ-25 (Suboptimal Health Status Questionnaire-25), whilst psychological symptoms were measured by DASS-21 (Depression, Anxiety and Stress Scale-21). …

Visitor Attitude To Tourism Destinations: A Critical Review And Future Research Agenda, Arghavan Hadinejad, Brent D. Moyle, Anna Kralj, Nick Noghan, Noel Scott, Sarah Gardiner

Research outputs 2022 to 2026

Visitor attitude is fundamental to destination selection in the tourism literature. Yet, there remains a notable dearth of critical reviews to assess the current status of knowledge on the topic. This study, therefore, seeks to map and critically evaluate the state of visitor attitudinal research to set the agenda for future scholarly enquiry. A review of journal articles on the topic in four leading tourism journals was undertaken. To critically explore the literature and identify research trends, a paradigm funnel approach was used. The findings demonstrate that most studies on the topic are based on empirical research and specific theories, …

Will Return-To-Office Mandates Prevent Proximity Bias For Employees Working From Home?, Sue Williamson, Uma Jogulu, Judy Lundy, Helen Taylor

Research outputs 2022 to 2026

This Practice and Policy article examines return-to-office mandates, the latest human resource controversy. These mandates are an organisational directive for employees who have been working from home to return to working in their employer's premise. Drawing on the literature and our research on working from home and hybrid working, we consider whether mandates may prevent proximity bias. We conclude that mandates requiring employees to return to the office or caps which limit working from home are not only unnecessary, but may have negative consequences. In particular, mandates may cause employee resentment, while caps limit flexibility and autonomy. We therefore do …

Uncovering The Green Procurement Knowledge Structure: A Systematic Citation Network Analysis, Abderahman Rejeb, Karim Rejeb, Andrea Appolloni, John G. Keogh, Mohammad Iranmanesh

Research outputs 2022 to 2026

Recently, academics and practitioners have devoted considerable attention to studying green procurement. Due to the growing number of articles in this fast-evolving domain, it is critical to examine the current body of knowledge thoroughly. The knowledge structure and dissemination channels in this field have been systematically examined for the first time. Four hundred fifty-two Scopus journal articles were analysed using keyword co-occurrence network and main path analysis (MPA) to identify the important research topics and historical evolution of green procurement research. The findings indicate that the literature focuses on multiple topics, including green supply chain management, sustainable public procurement, sustainability, …

From Grain To Malt: Tracking Changes Of Ultra-Low-Gluten Barley Storage Proteins After Malting, Mahya Bahmani, Angéla Juhász, Utpal Bos, Mitchell G. Nye-Wood, Malcolm Blundell, Crispin A. Howitt, Michelle L. Colgrave

Research outputs 2022 to 2026

Barley (Hordeum vulgare L.) is a major cereal crop produced globally. Hordeins, the major storage proteins in barley, can trigger immune responses leading to celiac disease or symptoms associated with food allergy. Here, proteomics approaches were employed to investigate the proteome level changes of grain and malt from the malting barley cultivar, Sloop, and single-, double- and triple hordein-reduced lines. The triple hordein-reduced line is an ultra-low gluten barley cultivar, Kebari®. Using discovery proteomics, 2,688 and 3,034 proteins in the barley and malt samples were detected respectively. Through the application of targeted proteomics, a significant reduction in the quantity …

Are We Talking About The Same Thing? The Case For Stronger Connections Between Graduate And Worker Employability Research, Jos Akkermans, William E. Donald, Denise Jackson, Anneleen Forrier

Research outputs 2022 to 2026

Purpose and approach: This article presents the case for creating stronger connections between research on graduate and worker employability. We offer a narrative review of commonalities and differences between these research streams and offer thoughts and suggestions for further integration and mutual learning. Findings: We outline some of the main theories and concepts in the graduate and worker employability domains. Furthermore, we analyze how these show considerable overlap, though they have barely connected with each other yet. We also formulate an agenda for future research that would spur stronger connections between the fields. Finally, we turn to our fellow authors, …

Blood Eosinophil-Guided Oral Prednisolone For Copd Exacerbations In Primary Care In The Uk (Starr2): A Non-Inferiority, Multicentre, Double-Blind, Placebo-Controlled, Randomised Controlled Trial, Sanjay Ramakrishnan, Helen Jeffers, Beverly Langford-Wiley, Joanne Davies, Samantha J. Thulborn, Mahdi Mahdi, Christine A'Court, Ian Binnian, Stephen Bright, Simon Cartwright, Victoria Glover, Alison Law, Robin Fox, Adam Jones, Christopher Davies, David Copping, Richard E. K. Russell, Mona Bafadhel

Research outputs 2022 to 2026

Background: Systemic glucocorticoids are recommended for use in chronic obstructive pulmonary disease (COPD) exacerbations; however, there is increased harm associated with their use. We hypothesised that the use of eosinophil biomarker-directed oral prednisolone therapy at the time of an exacerbation of COPD was effective at reducing prednisolone use without affecting adverse outcomes. Methods: The studying acute exacerbations and response (STARR2) study was a multicentre, randomised, double-blind, placebo-controlled trial conducted in 14 primary care practices in the UK. We included adults (aged ≥ 40 years), who were current or former smokers (with at least a 10 pack year smoking history) with …

Customer Experience Quality With Social Robots: Does Trust Matter?, Sanjit K. Roy, Gaganpreet Singh, Saalem Sadeque, Richard L. Gruner

Research outputs 2022 to 2026

Although service providers increasingly adopt social robots, much remains to be learned about what influences customers' experiences with robots. To address this issue, this study investigates the relationships among customer equity drivers (i.e., value equity, brand equity and relationship equity), trust in social robots, and trust in service providers. Specifically, we hypothesize that customer equity drivers influence trust in social robots and trust in service providers. We also propose that customer equity drivers influence customer experience quality in the context of social robots and that trust in social robots and trust in service providers mediate these relationships. The study used …

Economic Material For Large-Scale H2 Storage And H2-Co2 Separation, Hussein R. Abid, Alireza Keshavarz, Header Jaffer, Basim K. Nile, Stefan Iglauer

Research outputs 2022 to 2026

Hydrogen is a clean fuel that can potentially completely decarbonize the energy supply chain and mitigate global warming. Hydrogen – a highly volatile gas – however, needs to be separated from CO2 during H2 production, and also from cushion gas in H2 geo-storage projects; in addition, large-scale H2 storage is a key obstacle. We thus tested and chemically upgraded common sub-bituminous coal as a material for H2-CO2 separation and H2 storage. The coal adsorbed significant amounts of H2 and CO2 and demonstrated an excellent H2-CO2 separation efficiency if chemically modified. The work presented here thus provides fundamental data required for …

Hidden And Unacknowledged: The Mental Health And Psychosocial Interventions Delivered By School Nurses In Western Australia, Anita Moyes, Shirley Mcgough, Dianne Wynaden

Research outputs 2022 to 2026

Schools are an important setting for the early identification, assessment and intervention of mental health problems in children and young people. Internationally, many nurses work in schools, but the role of this group with young people experiencing mental health problems has had only limited investigation. This study explored the activities school nurses undertook with young people experiencing mental health problems in Australia. Reporting was guided by the COREQ checklist. Thirty-one nurses participated in a semi-structured interview. Data were analysed using the constant comparative method of analysis as developed by Glaser and Strauss (1967). The findings identified that nurses working in …

Quantitative Comparison Of Presenilin Protein Expression Reveals Greater Activity Of Ps2-Γ-Secretase, Melissa K. Eccles, Nathan Main, Rodrigo Carlessi, Ayeisha M. Armstrong, Miheer Sabale, Brigid Roberts-Mok, Janina E. E. Tirnitz-Parker, Mark Agostino, David Groth, Paul E. Fraser, Giuseppe Verdile

Research outputs 2022 to 2026

γ-secretase processing of amyloid precursor protein (APP) has long been of interest in the pathological progression of Alzheimer's disease (AD) due to its role in the generation of amyloid- . The catalytic component of the enzyme is the presenilins of which there are two homologues, Presenilin-1 (PS1) and Presenilin-2 (PS2). The field has focussed on the PS1 form of this enzyme, as it is typically considered the more active at APP processing. However, much of this work has been completed without appropriate consideration of the specific levels of protein expression of PS1 and PS2. We propose that expression is an …