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Articles 199501 - 199530 of 1740871
Full-Text Articles in Entire DC Network
Reimagining The Language Of Engagement In A Post-Stakeholder World, Mark S. Reed, Bethann G. Merkle, Elizabeth Cook, Caitlin Hafferty, Adam P. Hejnowicz, Richard Holliman, Ian D. Marder, Ursula Pool, Christopher M. Raymond, Kenneth E. Wallen, David Whyte, Marta Ballesteros, Sadiq Bhanbhro, Siniša Borota, Marnie L. Brennan, Esther Carmen, Elaine A. Conway, Rosie Everett, Fiona Armstrong-Gibbs, Eric Jensen, Gerbrand Koren, Jenny Lockett, Pedi Obani, Seb O'Connor, Laurie Prange, Jon Mason, Simon Robinson, Priya Shukla, Anna Tarrant, Alessandro Marchetti, Mascha Stroobant
Reimagining The Language Of Engagement In A Post-Stakeholder World, Mark S. Reed, Bethann G. Merkle, Elizabeth Cook, Caitlin Hafferty, Adam P. Hejnowicz, Richard Holliman, Ian D. Marder, Ursula Pool, Christopher M. Raymond, Kenneth E. Wallen, David Whyte, Marta Ballesteros, Sadiq Bhanbhro, Siniša Borota, Marnie L. Brennan, Esther Carmen, Elaine A. Conway, Rosie Everett, Fiona Armstrong-Gibbs, Eric Jensen, Gerbrand Koren, Jenny Lockett, Pedi Obani, Seb O'Connor, Laurie Prange, Jon Mason, Simon Robinson, Priya Shukla, Anna Tarrant, Alessandro Marchetti, Mascha Stroobant
Research outputs 2022 to 2026
Language matters in shaping perceptions and guiding behaviour. The term stakeholder is widely used, yet little attention is paid to the possibility that its use may inadvertently perpetuate colonial narratives and reinforce systemic inequities. In this article, we critically examine the limitations of the stakeholder concept and its ambiguity, normativity, and exclusionary implications. We emphasise the importance of using language that gives a voice to marginalised groups, promotes inclusion and equity, and fosters meaningful and reflexive participation in decision-making processes. In critiquing the use of the term and calling for alternative practices, we aim to contribute to the decolonisation of …
Consequences Of Group-Based Misperceptions Of Climate Concern For Efficacy And Action, Zoe Leviston, Tanvi Nangrani, Samantha K. Stanley, Iain Walker
Consequences Of Group-Based Misperceptions Of Climate Concern For Efficacy And Action, Zoe Leviston, Tanvi Nangrani, Samantha K. Stanley, Iain Walker
Research outputs 2022 to 2026
People tend to underestimate others’ environmental values, including when judging the values of minority-status groups. Using a large national sample (N = 5110), we test whether these misperceptions extend to concern about climate change in Australia, and differ depending on immigrant status, ethnicity, and where one is located (i.e., in or outside capital cities). We also examine the consequences of misperceptions for self-efficacy and pro-environmental behaviour. We find personal climate concern is high, but perceptions of others’ concern is lower. Immigrants and Australian-born participants have similarly high concern, but both groups underestimate how concerned immigrants are. Southern-Central-Asian identifiers are the …
De+D61:D80signing Bespoke Visual Mediation Tools Using 'Viscourse' For Intergenerational Research Visiblising Pedagogies, Amelia Ruscoe, Penny Baker
De+D61:D80signing Bespoke Visual Mediation Tools Using 'Viscourse' For Intergenerational Research Visiblising Pedagogies, Amelia Ruscoe, Penny Baker
Research outputs 2022 to 2026
Visual methods are an innovative design space for study methodologies with young children. The accessibility of visual media, and flexibility of their design and use, has spurred methodological innovations that stretch the boundaries of intergenerational research. This article explores the visual dialogic nexus in research methods tailored to investigate discourse. The research sought to uncover the perspectives of young children and their teachers about their discursive affordances in the first year of school. Employing an iterative design process, bespoke visual mediation tools were collaboratively created with a visual artist to capture the intergenerational viewpoints of the participants. This article reconceptualises …
Different Methods Of Winning, Losing, And Training In Combat Sports And Their Relationship With Overall Competitive Winningness, Oliver R. Barley, Craig A. Harms
Different Methods Of Winning, Losing, And Training In Combat Sports And Their Relationship With Overall Competitive Winningness, Oliver R. Barley, Craig A. Harms
Research outputs 2022 to 2026
This study aimed to investigate how overall competitive winningness in combat sports depended on patterns of victory and loss, as well as training habits. Competitors (N = 280) from several combat sports participated in the study. The online survey included questions on self-reported patterns of victory (and loss), training habits, general demographics (e.g., age), and sport-specific information (e.g., stage of career and competitive style). Overall, it was found across four models that reflected diversity of winningness in combat sports that the most important predictors of competitive winningness were loss by points (negative), loss by submission (negative), loss (negative) or victory …
Editorial - Contemporary Marine Science, Its Utility And Influence On Regulation And Government Policy, Piers Larcombe, Angus Morrison-Saunders, Peter V. Ridd
Editorial - Contemporary Marine Science, Its Utility And Influence On Regulation And Government Policy, Piers Larcombe, Angus Morrison-Saunders, Peter V. Ridd
Research outputs 2022 to 2026
The purpose of this Research Topic is to evaluate the quality of contemporary marine science and to examine relationships between science, regulation and government policy in the marine environment. The quality of marine science matters; not just to advance knowledge on understanding marine ecosystems, but also to guide marine management. ...
First-Line Chemoimmunotherapy And Immunotherapy In Patients With Non-Small Cell Lung Cancer And Brain Metastases: A Registry Study, Lauren J. Brown, Victor Khou, Chris Brown, Marliese Alexander, Dasantha Jayamanne, Joe Wei, Lauren Gray, Wei Chan, Samuel Smith, Susan Harden, Antony Mersiades, Lydia Warburton, Malinda Itchins, Jenny H. Lee, Nick Pavlakis, Stephen J. Clarke, Michael Boyer, Adnan Nagrial, Eric Hau, Ines Pires Da Silva, Steven Kao, Benjamin Y. Kong
First-Line Chemoimmunotherapy And Immunotherapy In Patients With Non-Small Cell Lung Cancer And Brain Metastases: A Registry Study, Lauren J. Brown, Victor Khou, Chris Brown, Marliese Alexander, Dasantha Jayamanne, Joe Wei, Lauren Gray, Wei Chan, Samuel Smith, Susan Harden, Antony Mersiades, Lydia Warburton, Malinda Itchins, Jenny H. Lee, Nick Pavlakis, Stephen J. Clarke, Michael Boyer, Adnan Nagrial, Eric Hau, Ines Pires Da Silva, Steven Kao, Benjamin Y. Kong
Research outputs 2022 to 2026
Introduction: Brain metastases commonly occur in patients with non-small cell lung cancer (NSCLC). Standard first-line treatment for NSCLC, without an EGFR, ALK or ROS1 mutation, is either chemoimmunotherapy or anti-PD-1 monotherapy. Traditionally, patients with symptomatic or untreated brain metastases were excluded from the pivotal clinical trials that established first-line treatment recommendations. The intracranial effectiveness of these treatment protocols has only recently been elucidated in small-scale prospective trials. Methods: Patients with NSCLC and brain metastases, treated with first-line chemoimmunotherapy or anti-PD-1 monotherapy were selected from the Australian Registry and biObank of thoracic cancers (AURORA) clinical database covering seven institutions. The primary …
Further Development Of The Reflective Practice Questionnaire, Shane L. Rogers, Lon Van Winkle, Nicole Michels, Cherie Lucas, Hassan Ziada, Eduardo J. Da Silva, Amit Jotangia, Sebastian Gabrielsson, Silje Gustafsson, Lynn Priddis
Further Development Of The Reflective Practice Questionnaire, Shane L. Rogers, Lon Van Winkle, Nicole Michels, Cherie Lucas, Hassan Ziada, Eduardo J. Da Silva, Amit Jotangia, Sebastian Gabrielsson, Silje Gustafsson, Lynn Priddis
Research outputs 2022 to 2026
Background: This article provides an update of the Reflective Practice Questionnaire (RPQ). The original RPQ consisted of 40-items with 10-sub-scales. In this article, the RPQ is streamlined into a 10-item single reflective practice construct, and a 30-item extended version that includes additional sub-scales of confidence, uncertainty/ stress, and work satisfaction. Methods: A total of 501 university students filled out an online questionnaire that contained the original Reflective Practice Questionnaire, and two general measures of reflection: The Self-Reflection and Insight Scale, and the Rumination-Reflection Questionnaire. Results: Based on factor analysis, the RPQ was streamlined into a brief 10-item version, and an …
How Have We Measured Trial Outcomes Of Asthma Attack Treatment? A Systematic Review, Imran Howell, Aleksandra Howell, Sanjay Ramakrishnan, Mona Bafadhel, Ian Pavord
How Have We Measured Trial Outcomes Of Asthma Attack Treatment? A Systematic Review, Imran Howell, Aleksandra Howell, Sanjay Ramakrishnan, Mona Bafadhel, Ian Pavord
Research outputs 2022 to 2026
Background Asthma attacks are a common problem for people with asthma and are responsible for significant healthcare costs. There is interest in a precision medicine approach to treatment. However, the choice of trial outcome measures for asthma attack treatment is hampered by the absence of a consensus on suitability. We carried out a systematic review to understand the characteristics of outcome measures used in randomised controlled trials of asthma attack treatment. Have randomised controlled trials of asthma attack treatment measured outcomes that are useful to patients and healthcare providers? Methods The protocol was registered on PROSPERO (CRD42022311479). We searched for …
Parent Self-Efficacy And Its Relationship With Children's Screen Viewing: A Scoping Review, Stephanie C. Milford, Lynette Vernon, Joseph J. Scott, Nicola F. Johnson
Parent Self-Efficacy And Its Relationship With Children's Screen Viewing: A Scoping Review, Stephanie C. Milford, Lynette Vernon, Joseph J. Scott, Nicola F. Johnson
Research outputs 2022 to 2026
This scoping review examines the relationship between parent self-efficacy and children's screen viewing, to provide context, identify gaps and limitations of the current body of literature, and provide recommendations for future research. We identified 111 studies from a search of four academic databases, of which sixteen were within scope and met inclusion criteria. This review found that parents who identified as more self-efficacious in task-specific areas related to screen time had children with less screen viewing time. This finding suggests that parents who identify as more self-efficacious in these areas may implement more mediation strategies, in line with current public …
Performance Of Gender Diversity On Board Of Directors: The Case Of Indonesia, Juniarti, Ferry Jie
Performance Of Gender Diversity On Board Of Directors: The Case Of Indonesia, Juniarti, Ferry Jie
Research outputs 2022 to 2026
This study further explores women’s role in top management in Indonesia, where men still dominate that position. This study underlines the role of women’s boards of commissioners in producing better financial performance in the specific sectors, manufacturing and service sectors, where the power of women to lead these sectors is more optimal. The sample is selected from the Indonesia Stock Exchange for the period 2009–2018. The final sample is 780 observations. This study applies panel data, which is more robust when controlling heterogeneity. Data panel regression is applied to analyze data. This study finds that gender diversity harms market-based performance, …
Source-Specific Nitrate And Nitrite Intakes And Associations With Sociodemographic Factors In The Danish Diet Cancer And Health Cohort, Dorit W. Erichsen, Pratik Pokharel, Cecilie Kyrø, Jörg Schullehner, Liezhou Zhong, Catherine P. Bondonno, Frederik Dalgaard, Peter Hendriksen, Torben Sigsgaard, Jonathan M. Hodgson, Anja Olsen, Anne Tjønneland, Nicola P. Bondonno
Source-Specific Nitrate And Nitrite Intakes And Associations With Sociodemographic Factors In The Danish Diet Cancer And Health Cohort, Dorit W. Erichsen, Pratik Pokharel, Cecilie Kyrø, Jörg Schullehner, Liezhou Zhong, Catherine P. Bondonno, Frederik Dalgaard, Peter Hendriksen, Torben Sigsgaard, Jonathan M. Hodgson, Anja Olsen, Anne Tjønneland, Nicola P. Bondonno
Research outputs 2022 to 2026
Background: The dietary source and intake levels of nitrate and nitrite may govern its deleterious versus beneficial effects on human health. Existing evidence on detailed source-specific intake is limited. The objectives of this study were to assess nitrate and nitrite intakes from different dietary sources (plant-based foods, animal-based foods, and water), characterize the background diets of participants with low and high intakes, and investigate how sociodemographic and lifestyle factors associate with intake levels. Methods: In the Danish Diet, Cancer and Health Cohort, sociodemographic and lifestyle information was obtained from participants at enrolment (1993–1997). Source-dependent nitrate and nitrite intakes were calculated …
Teaching Stare Decisis To First-Year Law Students In Higher Education: A Pedagogical Blind Alley?, Kenneth Yin, Carmela De Maio
Teaching Stare Decisis To First-Year Law Students In Higher Education: A Pedagogical Blind Alley?, Kenneth Yin, Carmela De Maio
Research outputs 2022 to 2026
The doctrine of stare decisis is often explained in first-year law studies as synonymous with the doctrine of precedent and dichotomised into ratio decidendi and obiter dicta. This explanation of stare decisis is frequently supplemented by an exercise where the novice law student is provided with a case and directed to identify the ratio decidendi of the case, and to appreciate the distinction between ratio and obiter dicta in it, the latter being persuasive only. It is argued that this pedagogy is limited and unrealistic because stare decisis is a dynamic process whereby, applying the precepts of formal legal logic, …
Developing A Novel Ontology For Cybersecurity In Internet Of Medical Things-Enabled Remote Patient Monitoring, Kulsoom S. Bughio, David M. Cook, Syed A. A. Shah
Developing A Novel Ontology For Cybersecurity In Internet Of Medical Things-Enabled Remote Patient Monitoring, Kulsoom S. Bughio, David M. Cook, Syed A. A. Shah
Research outputs 2022 to 2026
IoT has seen remarkable growth, particularly in healthcare, leading to the rise of IoMT. IoMT integrates medical devices for real-time data analysis and transmission but faces challenges in data security and interoperability. This research identifies a significant gap in the existing literature regarding a comprehensive ontology for vulnerabilities in medical IoT devices. This paper proposes a fundamental domain ontology named MIoT (Medical Internet of Things) ontology, focusing on cybersecurity in IoMT (Internet of Medical Things), particularly in remote patient monitoring settings. This research will refer to similar-looking acronyms, IoMT and MIoT ontology. It is important to distinguish between the two. …
A Charging Strategy For Large Commercial Electric Vehicle Fleets, Bassam Al-Hanahi, Iftekhar Ahmad, Daryoush Habibi, Pravakar Pradhan, Mohammad A. S. Masoum
A Charging Strategy For Large Commercial Electric Vehicle Fleets, Bassam Al-Hanahi, Iftekhar Ahmad, Daryoush Habibi, Pravakar Pradhan, Mohammad A. S. Masoum
Research outputs 2022 to 2026
The popularity of Commercial Electric Vehicles (CEVs) has experienced a surge in recent years, particularly in urban vocational contexts, as a means of advancing towards the goal of attaining net-zero emissions by 2050. The return-to-base charging strategy, which involves charging CEVs at depots, has become a prevalent practice for smaller CEV fleets. Nevertheless, for larger CEV fleets, the limited charging capacity at depots presents a significant challenge, leading to a reliance on both limited depot charging infrastructure and public charging infrastructure. This reliance can have a substantial impact on both the operational costs and the sustainability of logistics services. To …
A Systematic Review Of K-12 Cybersecurity Education Around The World, Ahmed Ibrahim, Marnie Mckee, Leslie F. Sikos, Nicola F. Johnson
A Systematic Review Of K-12 Cybersecurity Education Around The World, Ahmed Ibrahim, Marnie Mckee, Leslie F. Sikos, Nicola F. Johnson
Research outputs 2022 to 2026
This paper presents a systematic review of K-12 cybersecurity education literature from around the world. 24 academic papers dated from 2013-2023 were eligible for inclusion in the literature established within the research protocol. An additional 19 gray literature sources comprised the total. A range of recurring common topics deemed as aspects of cybersecurity behavior or practice were identified. A variety of cybersecurity competencies and skills are needed for K-12 students to apply their knowledge. As may be expected to be the case with interdisciplinary fields, studies are inherently unclear in the use of their terminology, and this is compounded in …
Advancing Sustainable Malting Practices: Aquaporins As Potential Breeding Targets For Improved Water Uptake During Controlled Germination Of Barley (Hordeum Vulgare L.), Clare E. O’Lone, Angéla Juhász, Mitchell Nye-Wood, David Moody, Hugh Dunn, Jean P. Ral, Michelle L. Colgrave
Advancing Sustainable Malting Practices: Aquaporins As Potential Breeding Targets For Improved Water Uptake During Controlled Germination Of Barley (Hordeum Vulgare L.), Clare E. O’Lone, Angéla Juhász, Mitchell Nye-Wood, David Moody, Hugh Dunn, Jean P. Ral, Michelle L. Colgrave
Research outputs 2022 to 2026
The conversion of raw barley (Hordeum vulgare L.) to malt requires a process of controlled germination, where the grain is submerged in water to raise the moisture content to > 40%. The transmembrane proteins, aquaporins, influence water uptake during the initial stage of controlled germination, yet little is known of their involvement in malting. With the current focus on sustainability, understanding the mechanisms of water uptake and usage during the initial stages of malting has become vital in improving efficient malting practices. In this study, we used quantitative proteomics analysis of two malting barley genotypes demonstrating differing water-uptake phenotypes in the …
Airway Epithelium Respiratory Illnesses And Allergy (Aerial) Birth Cohort: Study Protocol, Elizabeth Kicic-Starcevich, David G. Hancock, Thomas Iosifidis, Patricia Agudelo-Romero, Jose A. Caparros-Martin, Yuliya V. Karpievitch, Desiree Silva, Lidija Turkovic, Peter N. Le Souef, Anthony Bosco, David J. Martino, Anthony Kicic, Susan L. Prescott, Stephen M. Stick
Airway Epithelium Respiratory Illnesses And Allergy (Aerial) Birth Cohort: Study Protocol, Elizabeth Kicic-Starcevich, David G. Hancock, Thomas Iosifidis, Patricia Agudelo-Romero, Jose A. Caparros-Martin, Yuliya V. Karpievitch, Desiree Silva, Lidija Turkovic, Peter N. Le Souef, Anthony Bosco, David J. Martino, Anthony Kicic, Susan L. Prescott, Stephen M. Stick
Research outputs 2022 to 2026
Introduction: Recurrent wheezing disorders including asthma are complex and heterogeneous diseases that affect up to 30% of all children, contributing to a major burden on children, their families, and global healthcare systems. It is now recognized that a dysfunctional airway epithelium plays a central role in the pathogenesis of recurrent wheeze, although the underlying mechanisms are still not fully understood. This prospective birth cohort aims to bridge this knowledge gap by investigating the influence of intrinsic epithelial dysfunction on the risk for developing respiratory disorders and the modulation of this risk by maternal morbidities, in utero exposures, and respiratory exposures …
Characterizing The Extent And Nature Of Digital Food And Beverage Marketing In Singapore – A Descriptive Study, Xin Hui Chua, Clare Whitton, Stefanie Vandevijvere, Bridget Kelly, Rob M. Van Dam, Salome A. Rebello
Characterizing The Extent And Nature Of Digital Food And Beverage Marketing In Singapore – A Descriptive Study, Xin Hui Chua, Clare Whitton, Stefanie Vandevijvere, Bridget Kelly, Rob M. Van Dam, Salome A. Rebello
Research outputs 2022 to 2026
Objective: To characterize the nature of digital food and beverage advertising in Singapore Setting: Food and beverage advertisements within 20 clicks on top 12 non-food websites and all posts on Facebook and Instagram pages of 15 major food companies in Singapore were sampled from January 1 to June 30, 2018. Design: Advertised foods were classified as being core (healthier), non-core or mixed-dishes (example burger) using the WHO nutrient profile model and national guidelines. Marketing techniques were assessed using published coding frameworks. Participants: NA Results: Advertisements (n=117) on the 12 non-food websites were largely presented as editorial content. Food companies posted …
Bioactive Components In The Marsupial Pouch And Milk, Manujaya W. Jayamanna Mohottige, Chloe E. Gardner, Mitchell G. Nye-Wood, Katherine A. Farquharson, Angéla Juhász, Katherine Belov, Carolyn J. Hogg, Emma Peel, Michelle L. Colgrave
Bioactive Components In The Marsupial Pouch And Milk, Manujaya W. Jayamanna Mohottige, Chloe E. Gardner, Mitchell G. Nye-Wood, Katherine A. Farquharson, Angéla Juhász, Katherine Belov, Carolyn J. Hogg, Emma Peel, Michelle L. Colgrave
Research outputs 2022 to 2026
Marsupials give birth to immunologically naïve young after a relatively short gestation period compared to eutherians. Consequently, the joey significantly relies on maternal protection, which is the focus of the present review. The milk and the pouch environment are essential contributors to maternal protection for the healthy development of joeys. In this review, we discuss bioactive components found in the marsupial pouch and milk that form cornerstones of maternal protection. These bioactive components include immune cells, immunoglobulins, the s100 family of calcium-binding proteins, lysozymes, whey proteins, antimicrobial peptides and other immune proteins. Furthermore, we investigated the possibility of the presence …
Exploratory Analysis Of Fight-Ending Punches In The Ultimate Fighting Championship™ Mixed Martial Arts Promotion, Oliver R. Barley, Colin S. Doherty, Mark Scanlan, Liam C. Tapsell, Corey Wilson, Julian Giustiniano, Matthew G. Plush, Shayne Vial
Exploratory Analysis Of Fight-Ending Punches In The Ultimate Fighting Championship™ Mixed Martial Arts Promotion, Oliver R. Barley, Colin S. Doherty, Mark Scanlan, Liam C. Tapsell, Corey Wilson, Julian Giustiniano, Matthew G. Plush, Shayne Vial
Research outputs 2022 to 2026
Punching is a crucial element of mixed martial arts (MMA), often leading to knockouts (KO) or technical knockouts (TKOs). This study explored the relative foot positions of athletes, their stances, punch type executed, and the reliability of these variables to provide insights into effective punch application in MMA. We retrospectively examined MMA contests from the Ultimate Fighting Championship that ended via KO/TKO (2020 to 2022). Data were sourced from publicly available videos on the internet. Three analysts, each with at least three years of experience in striking combat sports and competitive MMA, conducted observations independently. Only critical strikes where all …
Impact Of Successful Recanalization And Clinical Outcomes Of Patients With Acute Ischemic Stroke With 5 Or More Thrombectomy Passes, Sameh Samir Elawady, Ali Alawieh, Conor Cunningham, Sami Al Kasab, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios-Nikos Psychogios, Amir Shaban, Adam Arthur, Hugo Cuellar, Jonathan A Grossberg, Daniele G Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Richard Williamson, Pedro Navia, Peter Kan, Reade De Leacy, Shakeel Chowdhry, Mohamad Ezzeldin, Shinichi Yoshimura, Alejandro M Spiotta, Stroke Thrombectomy And Aneurysm Registry (Star) Collaborators
Impact Of Successful Recanalization And Clinical Outcomes Of Patients With Acute Ischemic Stroke With 5 Or More Thrombectomy Passes, Sameh Samir Elawady, Ali Alawieh, Conor Cunningham, Sami Al Kasab, Ilko Maier, Pascal Jabbour, Joon-Tae Kim, Stacey Quintero Wolfe, Ansaar Rai, Robert M Starke, Marios-Nikos Psychogios, Amir Shaban, Adam Arthur, Hugo Cuellar, Jonathan A Grossberg, Daniele G Romano, Omar Tanweer, Justin Mascitelli, Isabel Fragata, Adam Polifka, Joshua Osbun, Roberto Crosa, Charles Matouk, Min S Park, Michael R Levitt, Waleed Brinjikji, Mark Moss, Richard Williamson, Pedro Navia, Peter Kan, Reade De Leacy, Shakeel Chowdhry, Mohamad Ezzeldin, Shinichi Yoshimura, Alejandro M Spiotta, Stroke Thrombectomy And Aneurysm Registry (Star) Collaborators
Faculty, Staff and Students Publications
Background: As the number of thrombectomy passes increases during endovascular therapy (EVT) for acute stroke, neurointerventionalists must weigh the risks of potential complications against the risk of failing to recanalize the affected vessel. Thus, we investigated the effectiveness and safety of EVT for patients with acute stroke in which ≥5 EVT passes were performed.
Methods: This retrospective cohort study from January 2013 to December 2022 included 31 thrombectomy-capable centers. Patients in whom ≥5 EVT passes were made were included in the analysis. The patients with successful recanalization defined as modified Thrombolysis in Cerebral Infarction ≥2b at 5, 6, 7, or …
Neutrophil-Derived Activin-A Moderates Their Pro-Netotic Activity And Attenuates Collateral Tissue Damage Caused By Influenza A Virus Infection, Ariana Gavriil, Christina C Giannouli, Anastasia Apostolidou, Martyn L Foster, Martin M Matzuk, Panagiotis Skendros, Ioanna-Evdokia Galani, Paschalis Sideras
Neutrophil-Derived Activin-A Moderates Their Pro-Netotic Activity And Attenuates Collateral Tissue Damage Caused By Influenza A Virus Infection, Ariana Gavriil, Christina C Giannouli, Anastasia Apostolidou, Martyn L Foster, Martin M Matzuk, Panagiotis Skendros, Ioanna-Evdokia Galani, Paschalis Sideras
Faculty, Staff and Students Publications
BACKGROUND: Pre-neutrophils, while developing in the bone marrow, transcribe the Inhba gene and synthesize Activin-A protein, which they store and release at the earliest stage of their activation in the periphery. However, the role of neutrophil-derived Activin-A is not completely understood.
METHODS:To address this issue, we developed a neutrophil-specific Activin-A-deficient animal model (S100a8-Cre/Inhba fl/fl mice) and analyzed the immune response to Influenza A virus (IAV) infection. More specifically, evaluation of body weight and lung mechanics, molecular and cellular analyses of bronchoalveolar lavage fluids, flow cytometry and cell sorting of lung cells, as well as histopathological analysis of lung tissues, …
Developing A Pathway To Clinical Trials For Cacna1a-Related Epilepsies: A Patient Organization Perspective, Elsa Rossignol, Jeffrey L Noebels
Developing A Pathway To Clinical Trials For Cacna1a-Related Epilepsies: A Patient Organization Perspective, Elsa Rossignol, Jeffrey L Noebels
Faculty, Staff and Students Publications
CACNA1A-related disorders are rare neurodevelopmental disorders linked to variants in the CACNA1A gene. This gene encodes the α1 subunit of the P/Q-type calcium channel Cav2.1, which is globally expressed in the brain and crucial for fast synaptic neurotransmission. The broad spectrum of CACNA1A-related neurological disorders includes developmental and epileptic encephalopathies, familial hemiplegic migraine type 1, episodic ataxia type 2, spinocerebellar ataxia type 6, together with unclassified presentations with developmental delay, ataxia, intellectual disability, autism spectrum disorder, and language impairment. The severity of each disorder is also highly variable. The spectrum of CACNA1A-related seizures is broad across both loss-of-function and gain-of-function …
A Two-Stage Machine Learning Approach For Fake News Detection And News Article Categorization, Snegdha Adusumilli
A Two-Stage Machine Learning Approach For Fake News Detection And News Article Categorization, Snegdha Adusumilli
Master's Projects
This project employs machine learning techniques to develop a sequential model for detecting and categorizing fake news, aiming to mitigate its proliferation in today's digital landscape. The model operates in two phases: in the first phase, the classification algorithms like Naïve Bayes, XGBoost and Random Forest are used to distinguish between true and false news stories and in the second phase the capabilities of Naïve Bayes, XGBoost, Random Forest, and the Transformer-based BERT (Bidirectional Encoder Representations from Transformers) model are leveraged to further categorize the news into specific topics.
The methodology encompasses several key steps: data acquisition, preprocessing, feature extraction, …
Tremor In Cervical Dystonia, Joel S Perlmutter, Stewart Factor, Tobias Bäumer, Jeanne Feurestein, Erika Shelton, Steven Bellows, Joseph Jankovic, Abhimanyu Mahajan, Tila Wamer-Rosen, Stephen G Reich, Aparna Wagle Shukla, Irene Malaty, Alberto Espay, Kevin Duque, Mark S Ledoux, Rachel Saunders-Pullman, Katherine Leaver, Samuel Frank, Alexander Pantelyat, Victor Fung, Sarah Pirio Richardson, Brian Berman, Natividad Stover, Andres Deik, William Ondo, Christopher Groth, Hyder A Jinnah, Aasef G Shaikh
Tremor In Cervical Dystonia, Joel S Perlmutter, Stewart Factor, Tobias Bäumer, Jeanne Feurestein, Erika Shelton, Steven Bellows, Joseph Jankovic, Abhimanyu Mahajan, Tila Wamer-Rosen, Stephen G Reich, Aparna Wagle Shukla, Irene Malaty, Alberto Espay, Kevin Duque, Mark S Ledoux, Rachel Saunders-Pullman, Katherine Leaver, Samuel Frank, Alexander Pantelyat, Victor Fung, Sarah Pirio Richardson, Brian Berman, Natividad Stover, Andres Deik, William Ondo, Christopher Groth, Hyder A Jinnah, Aasef G Shaikh
Faculty, Staff and Students Publications
BACKGROUND: Cervical dystonia (CD) is the most common form of focal dystonia encountered in the clinic. Approximately one-third of CD patients have co-existing tremor in the head and hands. Assessment of tremor as regular or irregular in context of its oscillation trajectory, frequency, and amplitude is a major clinical challenge and can confound the diagnosis of CD. The misdiagnosis may lead to therapeutic failures, poor quality of life, and poor utilization of medical and financial resources.
METHODS: We analyzed the largest cohort of CD patients (
RESULTS: Out of 3,117 CD patients, 1,367 had neck tremor. The neck tremor was …
Secured Data Storage Management With Deduplication In Cloud Computing, Ganesh Regoti
Secured Data Storage Management With Deduplication In Cloud Computing, Ganesh Regoti
Master's Projects
In the cloud era, cloud storage has become a major service and the security of data and user privacy algorithms are becoming of great importance. This way, we make sure that the encrypted data is kept in the cloud storage. But, the challenges follow: First, storing encrypted data may result in ineffective utilization of cloud resources as in the provision of encrypted data, redundancy cannot be provided. Access control to the encrypted data is difficult as the underlying data is hidden and there is no metric with which the decision to share among users can be easily taken. Deduplication is …
Enhancing Environmental Health And Safety: Fine-Tuning Large Language Models For Domain-Specific Applications, Mohammad Adil Ansari
Enhancing Environmental Health And Safety: Fine-Tuning Large Language Models For Domain-Specific Applications, Mohammad Adil Ansari
Master's Projects
This study aims to simplify Environmental Health and Safety (EHS) by leveraging the power of Large Language Models (LLMs). In this research, we focus on fine-tuning three LLMs — LLaMA, Mistral, and Falcon — using PEFT techniques such as QLoRA and SFT, to address domain-specific needs such as safety compliance, incident reporting, and knowledge dissemination. Our research methodology involves fine-tuning each LLM model on a custom dataset compiled from various regulatory agencies, supplemented by targeted web scraping and manual collection of questionnaires to capture and enrich the models with the latest regulations and guidelines. This study aims to compare the …
Parallel Powerplay: Optimizing Performance With Mapreduce And Kubernetes Fusion, Shradha Chaturvedi
Parallel Powerplay: Optimizing Performance With Mapreduce And Kubernetes Fusion, Shradha Chaturvedi
Master's Projects
The combination of MapReduce (MR) & Kubernetes (K8s) strengths is not explored, and this study leverages the synergy between the two frameworks to meet the growing demands of data-intensive applications. First, this report elaborates on the existing literature work to understand the pros and cons of using MR and K8s, in what use cases these frameworks come to use, and investigates the effectiveness of research studies that explore the combination. This study aims to research the efficacy of the fusion of MR and K8s, considering these factors - application use case, infrastructure design, resource allocation, load balancing, and hypertuning parameters …
Satellite Handover Optimization Using Predicted Satellite-To-Base-Station Proximity, Pranathi Kunadi
Satellite Handover Optimization Using Predicted Satellite-To-Base-Station Proximity, Pranathi Kunadi
Master's Projects
Modern telecommunications heavily rely on Satellite communication networks to provide global coverage, especially in remote areas which link the whole world in a loop. Conventional handover algorithms methods rely on fixed and predefined rules and thresholds predefined statically to make a handover decision. However, these static handover algorithms may become inefficient under the changing conditions of the network. Therefore, it would be useful to measure the proximity order of satellites to the specific base station. Consequently, the assessed relative proximity helps in optimizing the handovers proactively inside related coverage areas. This results in the service quality and the delays in …
Personalized Medical Predictions, Bhargavi Chevva
Personalized Medical Predictions, Bhargavi Chevva
Master's Projects
Over the past few years, personalized medicine has gained traction due to its ability to solve medical issues efficiently for a person based on their personal characteristics. This project aims to design a machine-learning model that can generate predictions of lab test scores in the future based on past medical history. The model is trained using the MIMIC-4 (Medical Information Mart for Intensive Care) dataset that consists of medical records of over 40,000 patients. The proposed model, MOE-BEHRT, consists of Bidirectional Encoder Representations from Transformers on Electronic Health Records (BEHRT) and Mixture of Experts (MOE). The BEHRT model was originally …