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Articles 179251 - 179280 of 1740949

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X-Ray Polarimetry Of The Dipping Accreting Neutron Star 4u 1624–49, M Lynne Saade, Philip Kaaret, Andrea Gnarini, Juri Poutanen, Francesco Ursini, Stefano Bianchi, Anna Bobrikova, Fabio La Monaca, Alessandro Di Marco, Fiamma Capitanio, Alexandra Veledina, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. García, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Tsunefumi Mizuno, Fabio Muleri, Michela Negro, Chi-Yung Ng, Stephen L. O'Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie, Silvia Zane Mar 2024

X-Ray Polarimetry Of The Dipping Accreting Neutron Star 4u 1624–49, M Lynne Saade, Philip Kaaret, Andrea Gnarini, Juri Poutanen, Francesco Ursini, Stefano Bianchi, Anna Bobrikova, Fabio La Monaca, Alessandro Di Marco, Fiamma Capitanio, Alexandra Veledina, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. García, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Tsunefumi Mizuno, Fabio Muleri, Michela Negro, Chi-Yung Ng, Stephen L. O'Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie, Silvia Zane

Faculty Publications

We present the first X-ray polarimetric study of the dipping accreting neutron star 4U 1624−49 with the Imaging X-ray Polarimetry Explorer. We report a detection of polarization in the nondip time intervals with a confidence level of 99.99%. We find an average polarization degree (PD) of 3.1% ± 0.7% and a polarization angle of 81° ± 6° east of north in the 2–8 keV band. We report an upper limit on the PD of 22% during the X-ray dips with 95% confidence. The PD increases with energy, reaching from 3.0% ± 0.9% in the 4–6 keV band to 6% ± …

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X-Ray Polarization Of The Black Hole X-Ray Binary 4u 1630–47 Challenges The Standard Thin Accretion Disk Scenario, Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra, Alexandra Veledina, Valery F. Suleimanov, Nicole Rodriguez Cavero, James F. Steiner, Jiří Svoboda, Andrea Marinucci, Stefano Bianchi, Michela Negro, Giorgio Matt, Francesco Tombesi, Juri Poutanen, Adam Ingram, Roberto Taverna, Andrew West, Vladimir Karas, Francesco Ursini, Paolo Soffitta, Fiamma Capitanio, Domenico Viscolo, Alberto Manfreda, Fabio Muleri, Maxime Parra, Banafsheh Beheshtipour, Sohee Chun, Nicolò Cibrario, Niccolò Di Lalla, Sergio Fabiani, Kun Hu, Philip Kaaret, Vladislav Loktev, Romana Mikušincová, Tsunefumi Mizuno, Nicola Omodei, Pierre-Olivier Petrucci, Simonetta Puccetti, John Rankin, Silvia Zane, Sixuan Zhang, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Alessandro Di Marco, Immacolata Donnarumma, Victor Doroshenko, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Fabio La Monaca, Luca Latronico, Ioannis Liodakis, Simone Maldera, Frédéric Marin, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Ikuyuki Mitsuishi, Stephen C.-Y. Ng, Stephen L. O'Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Maura Pilia, Andrea Possenti, Brian D. Ramsey, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie Mar 2024

X-Ray Polarization Of The Black Hole X-Ray Binary 4u 1630–47 Challenges The Standard Thin Accretion Disk Scenario, Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra, Alexandra Veledina, Valery F. Suleimanov, Nicole Rodriguez Cavero, James F. Steiner, Jiří Svoboda, Andrea Marinucci, Stefano Bianchi, Michela Negro, Giorgio Matt, Francesco Tombesi, Juri Poutanen, Adam Ingram, Roberto Taverna, Andrew West, Vladimir Karas, Francesco Ursini, Paolo Soffitta, Fiamma Capitanio, Domenico Viscolo, Alberto Manfreda, Fabio Muleri, Maxime Parra, Banafsheh Beheshtipour, Sohee Chun, Nicolò Cibrario, Niccolò Di Lalla, Sergio Fabiani, Kun Hu, Philip Kaaret, Vladislav Loktev, Romana Mikušincová, Tsunefumi Mizuno, Nicola Omodei, Pierre-Olivier Petrucci, Simonetta Puccetti, John Rankin, Silvia Zane, Sixuan Zhang, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Alessandro Di Marco, Immacolata Donnarumma, Victor Doroshenko, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Fabio La Monaca, Luca Latronico, Ioannis Liodakis, Simone Maldera, Frédéric Marin, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Ikuyuki Mitsuishi, Stephen C.-Y. Ng, Stephen L. O'Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Maura Pilia, Andrea Possenti, Brian D. Ramsey, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie

Faculty Publications

A large energy-dependent X-ray polarization degree is detected by the Imaging X-ray Polarimetry Explorer (IXPE) in the high-soft emission state of the black hole X-ray binary 4U 1630–47. The highly significant detection (at ≈50σ confidence level) of an unexpectedly high polarization, rising from ∼6% at 2 keV to ∼10% at 8 keV, cannot be easily reconciled with standard models of thin accretion disks. In this work, we compare the predictions of different theoretical models with the IXPE data and conclude that the observed polarization properties are compatible with a scenario in which matter accretes onto the black hole through a …

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Regulation Of Normal And Aberrant Heterochromatic Gene Silencing In Yeast, Anabelle Acosta Mar 2024

Regulation Of Normal And Aberrant Heterochromatic Gene Silencing In Yeast, Anabelle Acosta

Honors Capstones

No abstract provided.

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Do Nitrogen And Phosphorus Influence Channel Catfish Growth In A Great Plains River?, Camden E. Oathout, Mark A. Pegg Mar 2024

Do Nitrogen And Phosphorus Influence Channel Catfish Growth In A Great Plains River?, Camden E. Oathout, Mark A. Pegg

International Journal of Undergraduate Research and Creative Activities

Evaluating abiotic environmental factors that influence growth of sportfish is key to understanding population dynamics and making appropriate management decisions. This is especially true in river systems where primary and secondary productivity can vary across temporal and spatial scales. In this study, we assessed fish responses to ambient nutrient levels (total nitrogen and total phosphorus) using growth rates determined from age-1 Channel Catfish, Ictalurus punctatus, in Platte River, Nebraska. Water quality and growth data were collected from sites across the central and lower Platte River from 2007 to 2013. We analyzed Platte River water quality data to find yearly average …

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Embodied Action In Remote Online Interaction: A Preliminary Investigation Of Hand Raising Gestures In A Zoom Meeting, Angela Garcia Mar 2024

Embodied Action In Remote Online Interaction: A Preliminary Investigation Of Hand Raising Gestures In A Zoom Meeting, Angela Garcia

Natural & Applied Sciences Faculty Publications

In this paper I use a conversation analytic approach to investigate how participants in a meeting held remotely via Zoom use embodied action to solicit selection as next speaker. When hand raising is not immediately successful, participants use embodied actions to withdraw, modify, upgrade, downgrade or reissue gestures in pursuit of selection as next speaker. Due to the technological affordances and limitations of the remote meeting environment, participants’ gestures and hand positions differ from what would typically occur in face-to-face interaction, resulting in frequent gestures near the face that provide for both visibility to the Zoom audience and easy transition …

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Considering Returns On Federal Investment In The Negotiated “Maximum Fair Price” Of Drugs Under The Inflation Reduction Act: An Analysis, Edward W. Zhou, Paula G. Chaves Da Silva, Debbie Quijada, Fred D. Ledley Mar 2024

Considering Returns On Federal Investment In The Negotiated “Maximum Fair Price” Of Drugs Under The Inflation Reduction Act: An Analysis, Edward W. Zhou, Paula G. Chaves Da Silva, Debbie Quijada, Fred D. Ledley

Natural & Applied Sciences Faculty Publications

The Inflation Reduction Act (IRA) of 2022 contained landmark provisions authorizing government to negotiate a “maximum fair price” for selected Medicare Part D drugs considering the manufacturer’s research and development costs, federal support for discovery and development, the extent to which the drugs address unmet medical needs, and other factors. This working paper describes federal investment in the discovery and development of the ten drugs selected for price negotiation in the first year of the IRA as well as the health value created through Medicare Part D spending on these drugs. We identified $11.7 billion in NIH funding for basic …

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Speculating About Genocide: The Queensland Frontier 1859–1897, Mark Finnane, Jonathan Richards Mar 2024

Speculating About Genocide: The Queensland Frontier 1859–1897, Mark Finnane, Jonathan Richards

Faculty Publications

In the colonisation of Queensland, Australia it is commonly accepted that large numbers of Indigenous people were killed in the second half of the nineteenth century. Calculations of violent mortality have recently been revised radically upwards. We suggest that the methodology deployed in these new studies is unreliable, reflecting errors in counting and calculation, as well as underestimating the selection bias of the samples. We caution against projecting aggregate violent mortality where the underlying data are so imperfect and emphasise the value of more detailed local and regional studies to inform better understanding of colonisation's impact on First Peoples.

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Influence Of Hesperidin On The Physico-Chemical, Microbiological And Sensory Characteristics Of Frozen Yogurt †, Roberto Cedillos, Ricardo S. Aleman, Ryan Page, Douglas W. Olson, Charles Boeneke, Witoon Prinyawiwatkul, Kayanush Aryana Mar 2024

Influence Of Hesperidin On The Physico-Chemical, Microbiological And Sensory Characteristics Of Frozen Yogurt †, Roberto Cedillos, Ricardo S. Aleman, Ryan Page, Douglas W. Olson, Charles Boeneke, Witoon Prinyawiwatkul, Kayanush Aryana

Faculty Publications

Frozen yogurts contain yogurt culture bacteria, which might impart health benefits to their consumers. Global frozen yogurt market sales are expected to grow by 4.8% by 2028, which represents an important opportunity for the industry, consumers and researchers. Polyphenols are metabolites found in plants which have antioxidant and anti-inflammatory properties and might prevent chronic diseases such as cancer, diabetes and cardiovascular diseases. The objective of this study was to elucidate the effect of the polyphenol hesperidin on the physico-chemical, microbiological and sensory characteristics of frozen yogurts. Hesperidin was incorporated into frozen yogurt at three concentrations (125, 250 and 500 mg/90 …

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Transformative Insights: Break Up With Salt (Buws) Program’S Short-Term Influence On Hypertension Risk Factors, Jean Pierre Enriquez, Helena Salgado, Christopher Kuetsinya, Li Hsiang Lin, Elizabeth Gollub Mar 2024

Transformative Insights: Break Up With Salt (Buws) Program’S Short-Term Influence On Hypertension Risk Factors, Jean Pierre Enriquez, Helena Salgado, Christopher Kuetsinya, Li Hsiang Lin, Elizabeth Gollub

Faculty Publications

Break Up with Salt (BUWS) is a four-session community-based nutrition education program aimed at reducing key controllable hypertension risk factors. This pilot study utilized a pre-post survey design to assess short-term outcomes on food behaviors (including DASH diet eating patterns), physical activity, and overall well-being, in two groups of participants. The first “pilot” group (n = 25) completed a comprehensive, 16-item survey; the second “abbreviated” group (n = 27) completed a 5-item survey. The pilot group experienced improvements in whole grain (p = 0.04), sweetened beverage consumption, watching/reducing sodium (p = 0.04) and fat (p = 0.05) consumption, and time …

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Seven-Year Prospective Study On Yearly Incidence Of Orbivirus Infection Of Captive White-Tailed Deer And Potential Culicoides Vectors, Michael Becker, Glen Gentry, Claudia Husseneder, Lane Foil Mar 2024

Seven-Year Prospective Study On Yearly Incidence Of Orbivirus Infection Of Captive White-Tailed Deer And Potential Culicoides Vectors, Michael Becker, Glen Gentry, Claudia Husseneder, Lane Foil

Faculty Publications

Bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) are arthropod-borne viruses that are transmitted by biting midges in the genus Culicoides (Diptera: Ceratopogonidae) and can cause hemorrhagic disease in certain ruminants. The objectives of this study were to measure the incidence of BTV and EHDV infections in captive white-tailed deer herd as well as tissues and corresponding presence of Culicoides midges at a location near Clinton, LA. During a 7-yr study with yearly outbreaks of hemorrhagic disease in the deer herd, 15 species of Culicoides were captured using Centers for Disease Control (CDC) black light traps. Reverse transcriptase quantitative …

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Sustainable Sweetpotato Production In The United States: Current Status, Challenges, And Opportunities, Justin George, Gadi V.P. Reddy, Phillip A. Wadl, William Rutter, Julianna Culbreath, Pierre W. Lau, Tahir Rashid, Matthew C. Allan, Suzanne D. Johaningsmeier, Amanda M. Nelson, Ming Li Wang, Augustine Gubba, Kai Shu Ling, Yan Meng, Daniel J. Collins, Sathish K. Ponniah, Prasanna H. Gowda Mar 2024

Sustainable Sweetpotato Production In The United States: Current Status, Challenges, And Opportunities, Justin George, Gadi V.P. Reddy, Phillip A. Wadl, William Rutter, Julianna Culbreath, Pierre W. Lau, Tahir Rashid, Matthew C. Allan, Suzanne D. Johaningsmeier, Amanda M. Nelson, Ming Li Wang, Augustine Gubba, Kai Shu Ling, Yan Meng, Daniel J. Collins, Sathish K. Ponniah, Prasanna H. Gowda

Faculty Publications

Sweetpotato (Ipomoea batatas L.) is an important staple crop cultivated in over 100 countries, and the storage roots and vines provide food for humans and livestock. Sweetpotato consumption and demand for its value-added products have increased significantly in the last two decades and have led to new cultivar development, expansion in acreage, and increased demand in the United States and its export markets. Despite the known nutritional components and other health benefits, further research is needed to characterize the genetic diversity and chemical composition related to their storage root qualities, essential in developing consumer-preferred cultivars that offer host plant resistance …

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Two-Pore Potassium Channel Trek-1 (K2p2.1) Regulates Nlrp3 Inflammasome Activity In Macrophages, Camille N. Immanuel, Bin Teng, Brittany E. Dong, Elizabeth M. Gordon, Charlean Luellen, Benjamin Lopez, Jeffrey Harding, Stephania A. Cormier, Elizabeth A. Fitzpatrick, Andreas Schwingshackl, Christopher M. Waters Mar 2024

Two-Pore Potassium Channel Trek-1 (K2p2.1) Regulates Nlrp3 Inflammasome Activity In Macrophages, Camille N. Immanuel, Bin Teng, Brittany E. Dong, Elizabeth M. Gordon, Charlean Luellen, Benjamin Lopez, Jeffrey Harding, Stephania A. Cormier, Elizabeth A. Fitzpatrick, Andreas Schwingshackl, Christopher M. Waters

Division of Basic Science Faculty Publications

Because of the importance of potassium efflux in inflammasome activation, we investigated the role of the two-pore potassium (K2P) channel TREK-1 in macrophage inflammasome activity. Using primary alveolar macrophages (AMs) and bone marrow-derived macrophages (BMDMs) from wild-type (wt) and TREK-1–/– mice, we measured responses to inflammasome priming [using lipopolysaccharide (LPS)] and activation (LPS þ ATP). We measured IL-1b, caspase-1, and NLRP3 via ELISA and Western blot. A membrane-permeable potassium indicator was used to measure potassium efflux during ATP exposure, and a fluorescence-based assay was used to assess changes in membrane potential. Inflammasome activation induced by LPS þ ATP increased IL-1b …

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Growing The Next Generation Of Horticulture Customers And Stakeholders Through Industry And Extension Outreach Collaborations1, Natalie Bumgarner, Alicia Rihn, Julie Campbell, Sheri Dorn, Heather Kirk-Ballard Mar 2024

Growing The Next Generation Of Horticulture Customers And Stakeholders Through Industry And Extension Outreach Collaborations1, Natalie Bumgarner, Alicia Rihn, Julie Campbell, Sheri Dorn, Heather Kirk-Ballard

Faculty Publications

As the horticulture consumer base transitions to younger generations, educational outreach collaborations between Extension and industry could be a mutually beneficial way to serve an increasingly diverse customer audience. A recent study investigated drivers of, and opportunities for, increased participation in plant-related activities using an online survey of 2,134 respondents. Both participants and non-participants in plant-related activities were surveyed. Some of the commonly cited reasons for non-participation were a lack of knowledge and overall success, illustrating an opportunity for education to be beneficial. While many plant retailers may not have the personnel or resources to engage widely in education, collaborations …

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An Island ‘Endemic’ Born Out Of Hybridization Between Introduced Lineages, Jessie F. Salter, Robb T. Brumfield, Brant C. Faircloth Mar 2024

An Island ‘Endemic’ Born Out Of Hybridization Between Introduced Lineages, Jessie F. Salter, Robb T. Brumfield, Brant C. Faircloth

Faculty Publications

Humans have profoundly impacted the distribution of plant and animal species over thousands of years. The most direct example of these effects is human-mediated movement of individuals, either through translocation of individuals within their range or through the introduction of species to new habitats. While human involvement may be suspected in species with obvious range disjunctions, it can be difficult to detect natural versus human-mediated dispersal events for populations at the edge of a species' range, and this uncertainty muddles how we understand the evolutionary history of populations and broad biogeographical patterns. Studies combining genetic data with archaeological, linguistic and …

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Identification Of A Chondrocyte-Specific Enhancer In The Hoxc8 Gene, Stephania A. Cormier, Claudia Kappen Mar 2024

Identification Of A Chondrocyte-Specific Enhancer In The Hoxc8 Gene, Stephania A. Cormier, Claudia Kappen

Division of Basic Science Faculty Publications

Hox genes encode transcription factors whose roles in patterning animal body plans during embryonic development are well-documented. Multiple studies demonstrate that Hox genes continue to act in adult cells, in normal differentiation, in regenerative processes, and, with abnormal expression, in diverse types of cancers. However, surprisingly little is known about the regulatory mechanisms that govern Hox gene expression in specific cell types, as they differentiate during late embryonic development, and in the adult organism. The murine Hoxc8 gene determines the identity of multiple skeletal elements in the lower thoracic and lumbar region and continues to play a role in the …

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Response To “The Importance Of Diversity In Obesity Articles”, Michael Jensen, Leanne Redman Mar 2024

Response To “The Importance Of Diversity In Obesity Articles”, Michael Jensen, Leanne Redman

Clinical Research Faculty Publications

No abstract provided.

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Harmonized Multisite Mri-Based Quantification Of Human Liver Fat And Stiffness: A Pilot Study, Owen T. Carmichael, Maninder Singh, Adil Bashir, Anne M. Russell, Mark Bolding, David T. Redden, Judd Storrs, William R. Willoughby, Candace Howard-Claudio, Daniel S. Hsia, Robert P. Kimberly, Meagan E. Gray, Eric Ravussin, Thomas S. Denney Mar 2024

Harmonized Multisite Mri-Based Quantification Of Human Liver Fat And Stiffness: A Pilot Study, Owen T. Carmichael, Maninder Singh, Adil Bashir, Anne M. Russell, Mark Bolding, David T. Redden, Judd Storrs, William R. Willoughby, Candace Howard-Claudio, Daniel S. Hsia, Robert P. Kimberly, Meagan E. Gray, Eric Ravussin, Thomas S. Denney

Clinical Research Faculty Publications

Background: Nonalcoholic fatty liver disease (NAFLD) is a leading cause of end-stage liver disease. NAFLD diagnosis and follow-up relies on a combination of clinical data, liver imaging, and/or liver biopsy. However, intersite imaging differences impede diagnostic consistency and reduce the repeatability of the multisite clinical trials necessary to develop effective treatments. Purpose/Hypothesis: The goal of this pilot study was to harmonize commercially available 3 T magnetic resonance imaging (MRI) measurements of liver fat and stiffness in human participants across academic sites and MRI vendors. Study Type: Cohort. Subjects: Four community-dwelling adults with obesity. Field strength/Sequence: 1.5 and 3 T, multiecho …

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Exercise-Induced Changes In Central Adiposity During An Rct: Effect Of Exercise Dose And Associations With Compensation, James L. Dorling, John W. Apolzan, Neil M. Johannsen, Diana M. Thomas, Christoph Höchsmann, Daniel S. Hsia, Corby K. Martin Mar 2024

Exercise-Induced Changes In Central Adiposity During An Rct: Effect Of Exercise Dose And Associations With Compensation, James L. Dorling, John W. Apolzan, Neil M. Johannsen, Diana M. Thomas, Christoph Höchsmann, Daniel S. Hsia, Corby K. Martin

Clinical Research Faculty Publications

Context: Exercise can decrease central adiposity, but the effect of exercise dose and the relationship between central adiposity and exercise-induced compensation is unclear. Objective: Test the effect of exercise dose on central adiposity change and the association between central adiposity and exercise-induced weight compensation. Methods: In this ancillary analysis of a 6-month randomized controlled trial, 170 participants with overweight or obesity (mean ± SD body mass index: 31.5 ± 4.7 kg/m2) were randomized to a control group or exercise groups that reflected exercise recommendations for health (8 kcal/kg/ week [KKW]) or weight loss and weight maintenance (20 KKW). Waist circumference …

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Genome-Wide Polygenic Risk Score For Ckd In Individuals With Apol1 High-Risk Genotypes, Ha My T. Vy, Steven G. Coca, Ashwin Sawant, Ankit Sakhuja, Orlando M. Gutierrez, Richard Cooper, Ruth J.F. Loos, Carol R. Horowitz, Ron Do, Girish N. Nadkarni Mar 2024

Genome-Wide Polygenic Risk Score For Ckd In Individuals With Apol1 High-Risk Genotypes, Ha My T. Vy, Steven G. Coca, Ashwin Sawant, Ankit Sakhuja, Orlando M. Gutierrez, Richard Cooper, Ruth J.F. Loos, Carol R. Horowitz, Ron Do, Girish N. Nadkarni

Faculty Publications

No abstract provided.

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Coastal Wetland Restoration Through The Lens Of Odum's Theory Of Ecosystem Development, Friedrich W. Keppeler, Annette S. Engel, Linda M. Hooper-Bùi, Paola C. López-Duarte, Charles W. Martin, Jill A. Olin, Katelyn J. Lamb, Michael J. Polito, Nancy N. Rabalais, Brian J. Roberts, Erick M. Swenson, Olaf P. Jensen Mar 2024

Coastal Wetland Restoration Through The Lens Of Odum's Theory Of Ecosystem Development, Friedrich W. Keppeler, Annette S. Engel, Linda M. Hooper-Bùi, Paola C. López-Duarte, Charles W. Martin, Jill A. Olin, Katelyn J. Lamb, Michael J. Polito, Nancy N. Rabalais, Brian J. Roberts, Erick M. Swenson, Olaf P. Jensen

Faculty Publications

Advancing ecological restoration assessments requires a more detailed consideration of species interactions and ecosystem processes. Most restoration projects rely on a few metrics not always directly linked with ecological theory. Here, we used Odum's theory of ecosystem development to assess and compare the ecosystem structure and services of created marshes (4–6 years old) with preexisting, reference marshes in a brackish water region of the Mississippi River Delta. We built ecosystem models for created and reference marshes that integrated large datasets of stomach contents, stable isotopes, and taxa abundances. Despite strong resemblance in community structure, created marshes were at an earlier …

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Evidence For Evolved Stellar Binary Mergers In Observed B-Type Blue Supergiants, Athira Menon, Andrea Ercolino, Miguel A. Urbaneja, Daniel J. Lennon, Artemio Herrero, Ryosuke Hirai, Norbert Langer, Abel Schootemeijer, Emmanouil Chatzopoulos, Juhan Frank, Sagiv Shiber Mar 2024

Evidence For Evolved Stellar Binary Mergers In Observed B-Type Blue Supergiants, Athira Menon, Andrea Ercolino, Miguel A. Urbaneja, Daniel J. Lennon, Artemio Herrero, Ryosuke Hirai, Norbert Langer, Abel Schootemeijer, Emmanouil Chatzopoulos, Juhan Frank, Sagiv Shiber

Faculty Publications

Blue supergiants are the brightest stars in their host galaxies, and yet their evolutionary status has been a long-standing problem in stellar astrophysics. In this pioneering work, we present a large sample of 59 early B-type supergiants in the Large Magellanic Cloud with newly derived stellar parameters and identify the signatures of stars born from binary mergers among them. We simulate novel 1D merger models of binaries consisting of post main-sequence giants with helium-rich cores (primaries) and main-sequence companions (secondaries), and consider the effects of interaction of the secondary with the core of the primary along with the mixing induced …

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Searches For Baryon Number Violation In Neutrino Experiments: A White Paper, P. S.B. Dev, L. W. Koerner, S. Saad, S. Antusch, M. Askins, K. S. Babu, J. L. Barrow, J. Chakrabortty, A. De Gouvêa, Z. Djurcic, S. Girmohanta, I. Gogoladze, M. C. Goodman, A. Higuera, D. Kalra, G. Karagiorgi, E. Kearns, V. A. Kudryavtsev, T. Kutter, M. Malinský, D. A. Martinez Caicedo, R. N. Mohapatra, P. Nath, S. Nussinov, J. P. Ochoa-Ricoux, V. Pec, A. Rafique, J. Rodriguez Rondon, R. Shrock, H. W. Sobel, T. Stokes, M. Strait, R. Svoboda Mar 2024

Searches For Baryon Number Violation In Neutrino Experiments: A White Paper, P. S.B. Dev, L. W. Koerner, S. Saad, S. Antusch, M. Askins, K. S. Babu, J. L. Barrow, J. Chakrabortty, A. De Gouvêa, Z. Djurcic, S. Girmohanta, I. Gogoladze, M. C. Goodman, A. Higuera, D. Kalra, G. Karagiorgi, E. Kearns, V. A. Kudryavtsev, T. Kutter, M. Malinský, D. A. Martinez Caicedo, R. N. Mohapatra, P. Nath, S. Nussinov, J. P. Ochoa-Ricoux, V. Pec, A. Rafique, J. Rodriguez Rondon, R. Shrock, H. W. Sobel, T. Stokes, M. Strait, R. Svoboda

Faculty Publications

Baryon number conservation is not guaranteed by any fundamental symmetry within the standard model, and therefore has been a subject of experimental and theoretical scrutiny for decades. So far, no evidence for baryon number violation has been observed. Large underground detectors have long been used for both neutrino detection and searches for baryon number violating processes. The next generation of large neutrino detectors will seek to improve upon the limits set by past and current experiments and will cover a range of lifetimes predicted by several Grand Unified Theories. In this White Paper, we summarize theoretical motivations and experimental aspects …

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X-Ray Polarimetry Of The Dipping Accreting Neutron Star 4u1624–49, M. Lynne Saade, Philip Kaaret, Andrea Gnarini, Juri Poutanen, Francesco Ursini, Stefano Bianchi, Anna Bobrikova, Fabio La Monaca, Alessandro Di Marco, Fiamma Capitanio, Alexandra Veledina, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak Mar 2024

X-Ray Polarimetry Of The Dipping Accreting Neutron Star 4u1624–49, M. Lynne Saade, Philip Kaaret, Andrea Gnarini, Juri Poutanen, Francesco Ursini, Stefano Bianchi, Anna Bobrikova, Fabio La Monaca, Alessandro Di Marco, Fiamma Capitanio, Alexandra Veledina, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak

Faculty Publications

We present the first X-ray polarimetric study of the dipping accreting neutron star 4U 1624−49 with the Imaging X-ray Polarimetry Explorer. We report a detection of polarization in the nondip time intervals with a confidence level of 99.99%. We find an average polarization degree (PD) of 3.1% ± 0.7% and a polarization angle of 81° ± 6° east of north in the 2–8 keV band. We report an upper limit on the PD of 22% during the X-ray dips with 95% confidence. The PD increases with energy, reaching from 3.0% ± 0.9% in the 4–6 keV band to 6% ± …

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Detection Of X-Ray Polarization From The Blazar 1es 1959+650 With The Imaging X-Ray Polarimetry Explorer, Manel Errando, Ioannis Liodakis, Alan P. Marscher, Herman L. Marshall, Riccardo Middei, Michela Negro, Abel Lawrence Peirson, Matteo Perri, Simonetta Puccetti, Pazit L. Rabinowitz, Iván Agudo, Svetlana G. Jorstad, Sergey S. Savchenko, Dmitry Blinov, Ioakeim G. Bourbah, Sebastian Kiehlmann, Evangelos Kontopodis, Nikos Mandarakas, Stylianos Romanopoulos, Raphael Skalidis, Anna Vervelaki, Francisco José Aceituno, Maria I. Bernardos, Giacomo Bonnoli, Víctor Casanova, Beatriz Agís-González, César Husillos, Alessandro Marchini, Alfredo Sota, Pouya M. Kouch, Elina Lindfors, Carolina Casadio, Juan Escudero Mar 2024

Detection Of X-Ray Polarization From The Blazar 1es 1959+650 With The Imaging X-Ray Polarimetry Explorer, Manel Errando, Ioannis Liodakis, Alan P. Marscher, Herman L. Marshall, Riccardo Middei, Michela Negro, Abel Lawrence Peirson, Matteo Perri, Simonetta Puccetti, Pazit L. Rabinowitz, Iván Agudo, Svetlana G. Jorstad, Sergey S. Savchenko, Dmitry Blinov, Ioakeim G. Bourbah, Sebastian Kiehlmann, Evangelos Kontopodis, Nikos Mandarakas, Stylianos Romanopoulos, Raphael Skalidis, Anna Vervelaki, Francisco José Aceituno, Maria I. Bernardos, Giacomo Bonnoli, Víctor Casanova, Beatriz Agís-González, César Husillos, Alessandro Marchini, Alfredo Sota, Pouya M. Kouch, Elina Lindfors, Carolina Casadio, Juan Escudero

Faculty Publications

Observations of linear polarization in the 2-8 keV energy range with the Imaging X-ray Polarimetry Explorer (IXPE) explore the magnetic field geometry and dynamics of the regions generating nonthermal radiation in relativistic jets of blazars. These jets, particularly in blazars whose spectral energy distribution peaks at X-ray energies, emit X-rays via synchrotron radiation from high-energy particles within the jet. IXPE observations of the X-ray-selected BL Lac-type blazar 1ES 1959+650 on 2022 May 3-4 showed a significant linear polarization degree of Πx = 8.0% ± 2.3% at an electric-vector position angle ψ x = 123° ± 8°. However, on 2022 June …

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Systematic Kmtnet Planetary Anomaly Search. X. Complete Sample Of 2017 Prime-Field Planets, Yoon Hyun Ryu, Andrzej Udalski, Jennifer C. Yee, Weicheng Zang, Yossi Shvartzvald, Cheongho Han, Andrew Gould, Michael D. Albrow, Sun Ju Chung, Kyu Ha Hwang, Youn Kil Jung, In Gu Shin, Hongjing Yang, Sang Mok Cha, Dong Jin Kim, Seung Lee Kim, Chung Uk Lee, Dong Joo Lee, Yongseok Lee, Byeong Gon Park, Richard W. Pogge, Hanyue Wang, Przemek Mróz, Michał K. Szymański, Jan Skowron, Radek Poleski, Igor Soszyński, Paweł Pietrukowicz, Szymon Kozłowski, Krzysztof Ulaczyk, Krzysztof A. Rybicki, Patryk Iwanek, Marcin Wrona Mar 2024

Systematic Kmtnet Planetary Anomaly Search. X. Complete Sample Of 2017 Prime-Field Planets, Yoon Hyun Ryu, Andrzej Udalski, Jennifer C. Yee, Weicheng Zang, Yossi Shvartzvald, Cheongho Han, Andrew Gould, Michael D. Albrow, Sun Ju Chung, Kyu Ha Hwang, Youn Kil Jung, In Gu Shin, Hongjing Yang, Sang Mok Cha, Dong Jin Kim, Seung Lee Kim, Chung Uk Lee, Dong Joo Lee, Yongseok Lee, Byeong Gon Park, Richard W. Pogge, Hanyue Wang, Przemek Mróz, Michał K. Szymański, Jan Skowron, Radek Poleski, Igor Soszyński, Paweł Pietrukowicz, Szymon Kozłowski, Krzysztof Ulaczyk, Krzysztof A. Rybicki, Patryk Iwanek, Marcin Wrona

Faculty Publications

We complete the analysis of planetary candidates found by the KMT AnomalyFinder for the 2017 prime fields that cover ∼13 deg2. We report three unambiguous planets: OGLE-2017-BLG-0640, OGLE-2017-BLG-1275, and OGLE-2017-BLG-1237. The first two of these were not previously identified, while the last was not previously published due to technical complications induced by a nearby variable. We further report that a fourth anomalous event, the previously recognized OGLE-2017-BLG-1777, is very likely to be planetary, although its light curve requires unusually complex modeling because the lens and source both have orbiting companions. One of the three unambiguous planets, OGLE-2017-BLG-1275, is …

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A Pragmatic Trial Of A Family-Centered Approach To Childhood Obesity Treatment: Rationale And Study Design, Amanda E. Staiano, Alyssa M. Button, Alison Baker, Robbie Beyl, Anne Marie Conn, Angela Lima, Jeanne Lindros, Robert L. Newton, Richard I. Stein, R. Robinson Welch, Stephen Cook, Denise E. Wilfley Mar 2024

A Pragmatic Trial Of A Family-Centered Approach To Childhood Obesity Treatment: Rationale And Study Design, Amanda E. Staiano, Alyssa M. Button, Alison Baker, Robbie Beyl, Anne Marie Conn, Angela Lima, Jeanne Lindros, Robert L. Newton, Richard I. Stein, R. Robinson Welch, Stephen Cook, Denise E. Wilfley

Population and Public Health Science Faculty Publications

Background: Family-based behavioral treatment (FBT) is an effective intensive health behavior and lifestyle treatment for obesity reduction in children and adolescents, but families have limited access. The purpose of this randomized, pragmatic, comparative effectiveness trial was to examine changes in child relative weight in a 12-month, enhanced standard of care (eSOC) intervention combined with FBT (eSOC+FBT) vs. eSOC alone. Methods: Children aged 6 to 15 years with obesity, and their primary caregiver, were recruited from primary care clinics. Families were randomized 1:1 to eSOC, a staged approach led by the primary care provider that gradually intensified dependent on a child's …

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Assembly And Repair Of Photosystem Ii In Chlamydomonas Reinhardtii, Himanshu S. Mehra, Xiaozhuo Wang, Brandon P. Russell, Nidhi Kulkarni, Nicholas Ferrari, Brent Larson, David J. Vinyard Mar 2024

Assembly And Repair Of Photosystem Ii In Chlamydomonas Reinhardtii, Himanshu S. Mehra, Xiaozhuo Wang, Brandon P. Russell, Nidhi Kulkarni, Nicholas Ferrari, Brent Larson, David J. Vinyard

Faculty Publications

Oxygenic photosynthetic organisms use Photosystem II (PSII) to oxidize water and reduce plastoquinone. Here, we review the mechanisms by which PSII is assembled and turned over in the model green alga Chlamydomonas reinhardtii. This species has been used to make key discoveries in PSII research due to its metabolic flexibility and amenability to genetic approaches. PSII subunits originate from both nuclear and chloroplastic gene products in Chlamydomonas. Nuclear-encoded PSII subunits are transported into the chloroplast and chloroplast-encoded PSII subunits are translated by a coordinated mechanism. Active PSII dimers are built from discrete reaction center complexes in a process facilitated by …

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Data Augmentation Enhances Plant-Genomic-Enabled Predictions, Osval A. Montesinos-López, Mario Alberto Solis-Camacho, Leonardo Crespo-Herrera, Carolina Saint Pierre, Gloria Isabel Huerta Prado, Sofia Ramos-Pulido, Khalid Al-Nowibet, Roberto Fritsche-Neto, Guillermo Gerard, Abelardo Montesinos-López, José Crossa Mar 2024

Data Augmentation Enhances Plant-Genomic-Enabled Predictions, Osval A. Montesinos-López, Mario Alberto Solis-Camacho, Leonardo Crespo-Herrera, Carolina Saint Pierre, Gloria Isabel Huerta Prado, Sofia Ramos-Pulido, Khalid Al-Nowibet, Roberto Fritsche-Neto, Guillermo Gerard, Abelardo Montesinos-López, José Crossa

Faculty Publications

Genomic selection (GS) is revolutionizing plant breeding. However, its practical implementation is still challenging, since there are many factors that affect its accuracy. For this reason, this research explores data augmentation with the goal of improving its accuracy. Deep neural networks with data augmentation (DA) generate synthetic data from the original training set to increase the training set and to improve the prediction performance of any statistical or machine learning algorithm. There is much empirical evidence of their success in many computer vision applications. Due to this, DA was explored in the context of GS using 14 real datasets. We …

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The Need And Impact Of Child Life Interventions And Support On Night Shift, Meranda Martin Rn, Elise Moloney Rn Bsn, Natani Condo Rn Bsn Mar 2024

The Need And Impact Of Child Life Interventions And Support On Night Shift, Meranda Martin Rn, Elise Moloney Rn Bsn, Natani Condo Rn Bsn

Nurse Residency

PICOT Question: For pediatric patients (P), how would having a Child Life resource available on night shift (I) improve (C) overall patient experience (O) during hospital stays (T)?

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Forging The Future: Strategic Approaches To Quantum Ai Integration For Industry Transformation, Meng Leong How, Sin Mei Cheah Mar 2024

Forging The Future: Strategic Approaches To Quantum Ai Integration For Industry Transformation, Meng Leong How, Sin Mei Cheah

CCX Research

The fusion of quantum computing and artificial intelligence (AI) heralds a transformative era for Industry 4.0, offering unprecedented capabilities and challenges. This paper delves into the intricacies of quantum AI, its potential impact on Industry 4.0, and the necessary change management and innovation strategies for seamless integration. Drawing from theoretical insights and real-world case studies, we explore the current landscape of quantum AI, its foreseeable influence, and the implications for organizational strategy. We further expound on traditional change management tactics, emphasizing the importance of continuous learning, ecosystem collaborations, and proactive approaches. By examining successful and failed quantum AI implementations, lessons …

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