Digital Commons Network^™

Pharmacological Management Of Fragile X Syndrome: A Systematic Review And Narrative Summary Of The Current Evidence, Lance V. Watkins, Seungyoun Moon, Lisa Burrows, Samuel Tromans, Julian Barwell, Rohit Shankar

Peninsula Medical School

Introduction: Fragile X syndrome (FXS) is the most common inherited cause of Intellectual Disability. There is a broad phenotype that includes deficits in cognition and behavioral changes, alongside physical characteristics. Phenotype depends upon the level of mutation in the FMR1 (fragile X messenger ribonucleoprotein 1) gene. The molecular understanding of the impact of the FMR1 gene mutation provides an opportunity to target treatment not only at symptoms but also on a molecular level. Methods: We conducted a systematic review to provide an up-to-date narrative summary of the current evidence for pharmacological treatment in FXS. The review was restricted to randomized, …

Investigations Of The Eutectic Formation And Skin Rejuvenation By Hyaluronan - Kojic Acid Dipalmitate System, Syed Waqar Hussain Shah, Sumbal Imran, Iram Bibi, Kashif Ali, Nadia Bashir

Karbala International Journal of Modern Science

Eutectic phenomenon has been investigated in binary system based on biopolymer hyaluronan (HN) and kojic acid dipalmitate (KAD). Solid-liquid phase diagram showed a significant dependence of melting points on weight fraction of KAD up to KAD < 0.5. A negligible regain to melting temperature of pure KAD occurred later. Simulations of molecular mechanics using a four-unit segment of HN and KAD revealed the interaction between carbonyl of KAD with 4-OH on N-acetylglucosamine unit of oligomer. Infrared vibrational spectroscopy also endorsed the existence of a weakly interacting system. Such behavior was expected due to steric hinderance and rigidity of biopolymer. The thermal decomposition temperature of HN (i.e., 215 °C) was increased to 322 °C in HK50 having HN and KAD in 1:50 w/w. Bioelectric impedance analysis revealed that these green materials could promote skin health in humans.

Synthesis And Characterization Of Renewable Heterogeneous Catalyst Zno Supported Biogenic Silica From Pineapple Leaves Ash For Sustainable Biodiesel Conversion, Nadila Pratiwi, Suriati Eka Putri, Yulia Shinta, Arya Ibnu Batara, Diana Eka Pratiwi, Abd Rahman, Nur Ahmad, Heryanto Heryanto

Karbala International Journal of Modern Science

This study reports on the first case of the low-cost and environmentally friendly ZnO/SiO2 heterogeneous catalyst from pineapple leaves ash (PLA). Catalyst shows excellent performance in catalyzing the transesterification of waste cooking oil (WCO) with methanol for biodiesel conversion. This study focuses on assessing the influence of Zn content on physicochemical characteristics, using XRD, FTIR, SEM, and N2 adsorption-desorption methods. In addition, three different Zn content levels (20, 25, and 30 %wt) were applied. The results showed that all ZnO/SiO2 samples exhibited characteristics suitable for use as catalyst with an average crystallite size of 31.83-34.15 nm, and a surface area …

On Achieving Strategic Fit For Suvidha Sanitary Napkins Distributed Under Pradhan Mantri Janaushadhi Program In India, Priyank Sinha, Romi Sainy, Chandra Prakash Garg

Management Dynamics

In this research paper, we discuss the transformation of India's menstrual hygiene product (MHP) market and the challenges faced in achieving a strategic fit for the Suvidha scheme within the Pradhan Mantri JanAushadhi program. The paper analyzes the misalignment in marketing and supply chain strategies with respect to the overall competitive strategy, and proposes optimal strategies for different consumer segments. It draws insights from Roger's diffusion model to target various adopter categories effectively. The paper emphasizes the need for continuous assessment, collaboration with stakeholders, and adaptation to ensure the scheme's success in providing affordable and eco-friendly sanitary napkins.

How Much Grammar Do Students Appreciate? A Case Study Of A Middle School Dual Immersion Program In San Antonio., Esther Hur, Rocio Ocon-Garrido

11th National Symposium on Spanish as a Heritage Language (Archived)

No abstract provided.

Translation In The Linguistic Landscape Along The Us Border With Mexico, Gabriel González Núñez

11th National Symposium on Spanish as a Heritage Language (Archived)

Cities are the hubs of the modern world, and in border towns between states with different languages, these hubs are bilingual. Such bilingual towns offer opportunities to examine the extent to which translation, including the decision to not translate, plays a role in shaping the public spaces of cities (see González Núñez & Meylaerts). This presentation seeks to do that by relying on the methods developed for the study of the linguistic landscape (e.g., Landry & Bourhis). It will report on such a study as carried out in Brownsville, a city that sits on the Texas border with Mexico. The …

Miscellaneous, Bruce R. Johnson

Sehnsucht: The C. S. Lewis Journal

Announcements:

Call for papers (The Abolition of Man 80 Years On)

The C. S. Lewis Correspondence Project

The Inaugural Undiscovered C.S. Lewis Conference (George Fox University, Newberg, Oregon September 5-8, 2024)

Submission guidelines, style guide, copyright notice, and order form.

Review Of The Nature Of Middle-Earth, Brenton D.G. Dickieson

Sehnsucht: The C. S. Lewis Journal

Review of J. R. R. Tolkien, The Nature of Middle-earth, ed. by Carl Hostetter (New York: Mariner Books, 2021). 464 pages, including appendices and index. $32.00. ISBN 9780358454601.

What And Why (Plague Poem, March 2021), Joe Ricke

Sehnsucht: The C. S. Lewis Journal

No abstract provided.

Desidero, Educáre: At The Winter Zoo, Mary Giudice

Sehnsucht: The C. S. Lewis Journal

No abstract provided.

Surprised By Similarity: C.S. Lewis And Thomas Merton On The Self, John M. Gillespie

Sehnsucht: The C. S. Lewis Journal

Although they never corresponded, and they never met, the Anglican professor C.S. Lewis and the Trappist monk Thomas Merton nevertheless wrote in strikingly similar terms of the “true self,” or a person redeemed by Christ, and a “false self,” the rebellious person one believes themselves to be, but is not. There is very little academic work on the confluence of Lewis and Merton, and none thus far that specifically addresses their shared concept of the self. The aim of this paper is to address this gap in scholarship and, through an intertextual investigation of each man’s major works, fill it. …

“A Noise Of Great Good Coming”: C. S. Lewis’S Dymer As A Spiritual Autobiography, Norbert Feinendegen

Sehnsucht: The C. S. Lewis Journal

C. S. Lewis is no doubt one of the most recognized Christian prose writers of the twentieth century. The same, however, cannot be said about his pre-Christian attempts to make a name for himself as a poet. His two volumes of poetry, Spirits in Bondage (1919) and Dymer (1926), received few positive reviews and found even fewer readers at the time of publication, and sadly they didn’t receive much attention after Lewis became famous as a Christian apologist and novelist.

I am going to argue that Dymer is a symbolic narrative in which every event on the level of the …

Frontmatter (Volume 17, Issue 1), Bruce R. Johnson

Sehnsucht: The C. S. Lewis Journal

General Editor's Note:

This year’s Table of Contents requires some explanation. As a young man, C. S. Lewis aspired to make his mark as a poet. His first two books remain testaments to that unrealized dream: Spirits in Bondage: A Cycle of Lyrics (1919) and his narrative poem, Dymer (1926). Don King has done much to refocus scholarly attention on the poetry of Lewis through C. S. Lewis, Poet: The Legacy of His Poetic Impulse (2001) and more recently in The Collected Poems of C. S. Lewis: A Critical Edition (2015). Jerry Root first advanced his own theory regarding the …

Recursos Educativos Abiertos (Rea) Para La Enseñanza De Español Como Lengua De Herencia: De La Búsqueda A La Creación, Jocelly G. Meiners, Flavia Belpoliti

11th National Symposium on Spanish as a Heritage Language (Archived)

En este taller, los participantes aprenderán sobre el valor y la utilidad de los REA y desarrollarán habilidades para identificar, evaluar e integrar distintos REA en sus cursos de español como lengua de herencia. El taller se enfocará en el proceso de búsqueda e implementación para finalizar con la creación de REA propios.

No Soy Intrusa: Testimonios Of Latina Doctoral Students, Maryann Rocha

11th National Symposium on Spanish as a Heritage Language (Archived)

The number of Latinas who earn a doctoral degree has increased steadily in the United States, however, the numbers fail to describe the experiences of doctoral Latina students.

The qualitative pilot study was conceived from a graduate Mexican American Studies course project. The study collected testimonio of three Latina doctoral students enrolled in a counseling program at a public university in Texas. Platica was utilized in the research methodology and design, a mutualistic approach that honors the participants testimonio instead of the classic approach of extracting information from the participants.

Latino Critical Theory and Theory in the Flesh were used …

Invasive Annual Grass Issues In Canadian Rangelands, V. Maloney

IGC Proceedings (1977-2023)

It has been understood for several years now that Canadian grasslands are among the world’s most endangered ecosystems. While the endangerment of the world’s coral reefs and rainforests may make the news more often, the increasingly fast decline of native Canadian grasslands is having a major impact on species diversity as well as global carbon supplies. In this paper, I will discuss the impact invasive annual grasses have had on two important rangeland ecosystems in Canada. Furthermore, strategies for protecting and restoring these invaluable lands will be discussed.

Guidelines For Optimal Use Of Near Infrared Spectroscopy (Nirs) With Sample Preparation And Presentation Across Instrument Platforms, D. W. Mcintosh

IGC Proceedings (1977-2023)

Guidelines for optimal use of near infrared spectroscopy (NIRS) with sample preparation and presentation across instrument platforms will cover methods and resources specifically for NIRS analysis. Recommendations for sample preprocessing and scanning required to ensure compatibility across calibrations will be highlighted. Proper calibration determinations, monitoring, and performance will be demonstrated to create a baseline for correct use. Additional materials about the use and reporting of nutritive content predictions for publication will be discussed. Goals of this topic session are to develop an understanding of the basics of NIRS technology and provide the basics to what a laboratory is required to …

Observing And Simulating Temperate Grasslands In Central Europe, C. Nendel

IGC Proceedings (1977-2023)

This presentation summarises recent activities to observe grassland features using remote sensing and uses this data to feed mechanistic simulation models for temperate grassland vegetation in Central Europe, in order to assess underlying processes that are difficult to observe. Public interest has recently focused on grassland ecosystem services, such as carbon stocks, nitrate retention and greenhouse gas emissions; variables that in principle can be simulated using models. However, current grassland models suffer from the fact that species dynamics in grasslands are very active, and may change in response to water supply and management. As different species come with different traits, …

The Effect Of Nitrogen Rates And Plant Density On Grain Yield Components And Persistence In Intermediate Wheatgrass (Thinopyrum Intermedium) And Mountain Rye (Secale Strictum), M. T. Newell, N. Munday, R. C. Hayes

IGC Proceedings (1977-2023)

Intermediate wheatgrass (IWG; Thinopyrum intermedium) and Mountain Rye (Mtn Rye; Secale strictum) have potential for release as dual-purpose (grazing and grain production) perennial grains in Australia due to their superior longevity compared to hybrid perennial wheats. Initially developed as perennial forage grasses, few management guidelines exist to inform agronomic practices to maximise grain yields and profitability in Australian environments. An experiment was established in 2020 to examine the effect of plant density and nitrogen rates on grain yield components. The experiment compared the two species (IWG, Mtn Rye) sown at three plant densities (50, 100 and 200 plants/m2) …

Participatory Evaluation Of Urochloa (Brachiaria) Grasses In The Cool Highlands Of Central Kenya, Elkana Nyambati, W. Ayako, S. K. Mailu

IGC Proceedings (1977-2023)

Grasslands are increasingly threatened by over exploitation, degradation and climate change that has undermined their productive capacity, leading led to inadequate quantity and quality feed. Urochloa grass, a native of eastern Africa has been widely improved and adapted as livestock forage. A farmer participatory study was conducted to evaluate productivity of eight Urochloa grasses (Urochloa brizantha cv. Marandu, U. brizantha cv. Xareas, U. brizantha cv. Piata, U. brizantha cv. MG4, U. decumbens cv. Basilisk, U. humidicola cv. Humidicola, U. humidicola cv. Llanero and Urochloa hybrid Mulato II) compared to controls of Pennisetum purpureum (Napier grass cv. Kakamega 1 …

Is There A Need For Tailored Graduate Programs For International Students?, K. T. Oduor, Lynn E. Sollenberger, J. Dubeux, L. M. D. Queiroz

IGC Proceedings (1977-2023)

International studies often present opportunities for capacity development and mentorship for students to equip them with the knowledge and skills to address the challenges in their home countries. Typically, international graduate students are drawn from diverse educational and cultural backgrounds different from those in their host countries. Adjusting to these changes might be challenging and time-consuming, thus influencing their academic journey. Understanding these challenges might provide international students the opportunity to address them in time and, where possible, seek help. In this paper, we discuss some graduate program-related challenges international students face and provide potential recommendations that might result in …

Differences In Carbon Sequestration And Water Use Between A Semi-Arid Native Grassland And Encroaching Vachellia Karroo Woodland, C. Weideman, A. R. Palmer, G. Carolyn, Kathleen Smart

IGC Proceedings (1977-2023)

Tree and shrub encroachment and proliferation in global grasslands and savannas is widely considered to imply a trade-off between ecosystem C and H2O regulating functions, based on the premise that increased C sequestration associated with higher woody biomass ostensibly drive declines in water production through concomitant increases in evapotranspiration (ET), but evidence for this across climatic and environmental gradients is equivocal. To evaluate these claims, we ran a paired eddy covariance experiment in a native semi-arid C4 grassland and adjacent encroaching Vachellia karroo woodland on the eastern seaboard of South Africa and compared ecosystem C and H2O budgets over nearly …

Soil Carbon Monitoring Program For Ranches In Dryland Ecosystems, David E. Prado-Tarango, S. Ates, J. Talbot

IGC Proceedings (1977-2023)

Implementation of ranching practices that lead to greater soil carbon sequestration has become increasingly important due to rising atmospheric CO2 levels. Sustainable ranching practices are suggested to improve soil health and sequester more carbon in the soil. However, there is a paucity of measured data from replicated on-farm studies to support this premise. Thus, we developed a soil carbon monitoring program for a ranch located in the state of Oregon. Our monitoring program is focused on measuring the net carbon budget and the soil carbon sequestration totals. To achieve this goal, we combined field-sampling data with the COMET-Farm model. A …

Answering Complex Questions As We Make Headway On Annual Grasses And Fire, T. Prather, L. Jones, E. Strand, G. Harrison, K. Johnston

IGC Proceedings (1977-2023)

Annual grasses challenge our ability to meet forage production and plant community conservation objectives. Direct competition, potential mutualism, and shortened fire return interval interplay resulting in complexity of how to meet challenges we face. Bromus tectorum presents challenges to sagebrush dominated plant communities with shortened fire return intervals and the advancing invasion of Ventenata dubia poses threats to forage production through competitive interactions that may involve mutualism to enhance V. dubia’s invasion of annual and perennial grass dominated plant communities. Use of fuel breaks can reduce the extent of fires and their proper function hinges on their reduced plant biomass …

Using Recurrent Phenotypical Selection To Improve Drought Tolerance Of Red Clover, M. Sahin, S. Reid, E. Sahin, S. Ates, S. Elias, David B. Hannaway

IGC Proceedings (1977-2023)

Red clover is one of the most important forage legumes in the world. It is utilized extensively in European and North American farming systems. Approximately, 4 million hectares of red clover are grown globally each year for forage production, soil improvement, and as a pollen and nectar source for pollinators (Riday, 2010). In North America, red clover is widely used in temperate regions for pasture, hay, and silage in combination with grasses for soil improvement and as a pollen and nectar source for bumblebees (Bombus). In the northwest, it is also grown for seed production (Anderson et al., 2016) with …

Legumes As A Biological Tool To Address The Sustainability Of Ruminant Production Systems, H. Sheridan, M. B. Lynch

IGC Proceedings (1977-2023)

Growing public concern regarding accelerated rates of climate change, the depletion and degradation of natural resources such as biodiversity water and soils, coupled with policy commitments to address these challenges, are placing increasing pressures to enhance sustainability metrics associated with agriculture in general, and ruminant production systems in particular. At EU and indeed global scale, there has probably never before been so many potentially conflicting challenges for agriculture. On one hand, agricultural systems need to produce more, to feed the increasing global human population, while at the same time being much less reliant on economically and environmentally costly chemical inputs …

How Do Artemisia Capillaris Population Respond To Grazing Management And Rain Reduction?, Li-Yuan Shi, Fu-Jiang Hou, Zhen Wang

IGC Proceedings (1977-2023)

Climate and human activities, such as drought event and livestock grazing, generally coupled to influence the structure and function of grassland ecosystems. However, most of previous studies focused on the isolated effects of grazing or drought on grassland ecosystems, with little attention paid to the combined effects of them. Further, we know little about how plants respond to grazing and drought at the population level. We conducted a grazing regime (enclosure, stop grazing, and heavy grazing) and drought manipulation experiment in a typical steppe to explore how grassland plants response to ongoing drought and grazing regimes at the population level. …

Development Of Forage Curriculum For Extension Educators In The Southeast Usa, L. S. Silva, L. Dillard, K. Mullenix, M. Wallau, J. J. Tucker, C. Vasco

IGC Proceedings (1977-2023)

In the Southeast USA, livestock production is one of the largest agricultural activities, and forages are the primary feed source. Most livestock systems are highly dependent on off-farm inputs to support forage production and animal performance, which elevates production costs and the activity's carbon footprint. There is a strong need to develop forage educational resources to enhance productivity, environmental sustainability, resilience, and profitability of agricultural systems in the region. This multi-disciplinary initiative was a collaboration among several land-grant Universities across the region. The objective was to develop decision tools and provide in-classroom training associated with hands-on demonstrations to Extension agents …

Photo Essays: Multimodal Competence In The Shl Classroom, Flavia Belpoliti

11th National Symposium on Spanish as a Heritage Language (Archived)

No abstract provided.

Biographical Indexicality In Comunidades Hispanas, Whitney Chappell

11th National Symposium on Spanish as a Heritage Language (Archived)

No abstract provided.